aminolevulinic acid has been researched along with Precancerous Conditions in 111 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
Precancerous Conditions: Pathological conditions that tend eventually to become malignant.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our recent studies showed that a new topical 5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) protocol using a light-emitting diode (LED) light source is an effective and successful treatment modality for five cases of oral verrucous hyperplasia (OVH) and one case of verrucous carcinoma." | 7.73 | Successful treatment of oral verrucous hyperplasia and oral leukoplakia with topical 5-aminolevulinic acid-mediated photodynamic therapy. ( Chen, HM; Chiang, CP; Tsai, T; Tu, PC; Yeh, CY; Yu, CH, 2005) |
| "Surveillance of patients with Barrett's esophagus or ulcerative colitis for dysplasia is confined to biopsy specimens taken randomly during endoscopy because dysplasia remains undetectable by visual inspection." | 5.30 | Endoscopic fluorescence detection of dysplasia in patients with Barrett's esophagus, ulcerative colitis, or adenomatous polyps after 5-aminolevulinic acid-induced protoporphyrin IX sensitization. ( Bäumler, W; Holstege, A; Knüchel, R; Messmann, H; Schölmerich, J, 1999) |
| "Laser therapy appears the best option among nonsurgical approaches for actinic cheilitis, and PDT showed higher efficacy when sequentially combined with 5% imiquimod." | 5.05 | Treatments of actinic cheilitis: A systematic review of the literature. ( Cornacchia, L; Lai, M; Longo, C; Pampena, R; Pellacani, G; Peris, K, 2020) |
| "Laryngeal lesions (N = 39; 21 after administration of delta-aminolevulinic acid (ALA)) were investigated with laser-induced fluorescence, and the results correlated to histopathologic grading in 4 groups: non/mild dysplasia (I), moderate dysplasia (II), severe dysplasia/cancer in situ (III), and carcinoma." | 3.74 | Fluorescence investigations to classify malignant laryngeal lesions in vivo. ( Andersson-Engels, S; Eker, C; Krogdahl, A; Rydell, R; Svanberg, K; Wahlberg, P, 2008) |
| "Our previous studies showed that oral verrucous hyperplasia (OVH) lesions can be successfully treated with a topical 5-aminolevulinic acid-mediated photodynamic therapy (topical ALA-PDT) protocol using a 635-nm light-emitting diode light source." | 3.74 | Photodynamic therapy outcome for oral verrucous hyperplasia depends on the clinical appearance, size, color, epithelial dysplasia, and surface keratin thickness of the lesion. ( Chen, HM; Cheng, SJ; Chiang, CP; Hung, HY; Tsai, T; Yu, CH, 2008) |
| "Our recent studies showed that a new topical 5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) protocol using a light-emitting diode (LED) light source is an effective and successful treatment modality for five cases of oral verrucous hyperplasia (OVH) and one case of verrucous carcinoma." | 3.73 | Successful treatment of oral verrucous hyperplasia and oral leukoplakia with topical 5-aminolevulinic acid-mediated photodynamic therapy. ( Chen, HM; Chiang, CP; Tsai, T; Tu, PC; Yeh, CY; Yu, CH, 2005) |
| "Eleven patients with high-grade mucosal dysplasia in a columnar-lined oesophagus and 2 patients with a squamous carcinoma (uT1) underwent photodynamic therapy (PDT) and argon-plasma coagulation (APC)." | 3.70 | [Photodynamic ablation and argon-plasma coagulation of premalignant and early-stage malignant lesions of the oesophagus--an alternative to surgery?]. ( Beger, HG; Orth, K; Rück, A; Russ, D; Stanescu, A, 1999) |
| "Four patients with known gastric adenoma (n = 1), macroscopically undetected but histologically proven esophageal squamous cell cancer (n = 1), suspected early cancer of the esophagus (n = 1), and multiple duodenal adenomas (n = 1) were sensitized with 5-aminolevulinic acid administered orally (15 mg/kg body weight)." | 3.70 | Endoscopic photodynamic diagnosis: oral aminolevulinic acid is a marker of GI cancer and dysplastic lesions. ( Hahn, EG; Hochberger, J; Mayinger, B; Reh, H, 1999) |
| "Fluorescence spectroscopy combined with 5-aminolevulinic acid-induced protoporphyrin IX was found as a valuable tool in the diagnosis of oral premalignancy." | 2.72 | Fluorescence spectroscopy combined with 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in detecting oral premalignancy. ( El-Maaytah, M; Hopper, C; Jerjes, W; Khalil, HS; MacRobert, AJ; Salih, V; Sharwani, A, 2006) |
| "Actinic cheilitis is difficult to treat because surgical treatments have significant adverse effects whereas less invasive procedures have uncertain efficacy." | 2.52 | Photodynamic therapy for actinic cheilitis: a systematic review. ( Falto-Aizpurua, L; Griffith, RD; Nouri, K; Yazdani Abyaneh, MA, 2015) |
| "Actinic keratosis is currently believed to be an early stage in the evolution of squamous cell carcinoma." | 2.42 | Topical and light-based treatments for actinic keratoses. ( Alam, M; Goldberg, LH; Silapunt, S, 2003) |
| "As the first stage of squamous cell carcinoma, actinic keratosis is worthy of prompt evaluation and active treatment." | 2.42 | Topical and light-based treatments for actinic keratoses. ( Alam, M; Goldberg, LH; Silapunt, S, 2003) |
| " The most common adverse event was increased vaginal discharge, other side effects include abdominal pain, vulvar pruritus, and vaginal bleeding." | 1.72 | Efficacy and safety of photodynamic therapy mediatied by 5-aminolevulinic acid for the treatment of vaginal high-grade intraepithelial lesions. ( Guo, H; Han, Q; Wu, Z; Zhang, X, 2022) |
| "Photodynamic therapy mediatied by 5-aminolevulinic acid is an effective and safe treatment for vaginal HSIL with minimal side effects." | 1.72 | Efficacy and safety of photodynamic therapy mediatied by 5-aminolevulinic acid for the treatment of vaginal high-grade intraepithelial lesions. ( Guo, H; Han, Q; Wu, Z; Zhang, X, 2022) |
| "The cost of topical treatments for actinic keratosis (AK) has historically been evaluated in relation to the number of lesions requiring treatment or simply by the price of a single tube/sachet of the drug used." | 1.51 | Evaluation of the treatment costs and duration of topical treatments for multiple actinic keratosis based on the area of the cancerization field and not on the number of lesions. ( Calzavara-Pinton, P; Hamon, P; Tanova, N, 2019) |
| "Oral cancer is a common cancer with a high mortality rate." | 1.51 | MAL-PDT inhibits oral precancerous cells and lesions via autophagic cell death. ( Chen, YK; Cheng, KH; Chi, TC; Hu, CS; Huang, WL; Wang, YM; Wang, YY; Xiao, LY; Yuan, SF, 2019) |
| "Actinic keratosis is one of the most commonly treated skin conditions." | 1.38 | The interpretation of clinical studies on the photodynamic treatment of actinic keratosis. ( Kelleher, DK; Piazena, H, 2012) |
| "They included squamous cell carcinoma (SCC), basal cell carcinoma (BCC), Bowen's disease (BD), mammary and extramammary Paget disease, actinic keratosis (AK) and erythroplasia of Queyrat." | 1.35 | Treatment of skin cancer and pre-cancer using topical ALA-PDT--a single hospital experience. ( Guo, MX; Wang, HW; Wang, XL; Xu, SZ, 2008) |
| "So far, we have treated 76 cases of skin cancer and pre-cancer using topical ALA-PDT." | 1.35 | Treatment of skin cancer and pre-cancer using topical ALA-PDT--a single hospital experience. ( Guo, MX; Wang, HW; Wang, XL; Xu, SZ, 2008) |
| "Early diagnosis of laryngeal cancer and its precursor lesions is simplified." | 1.34 | Indirect fluorescence laryngoscopy in the diagnosis of precancerous and cancerous laryngeal lesions. ( Arens, C; Betz, CS; Glanz, H; Leunig, A; Reussner, D; Woenkhaus, J, 2007) |
| "14 patients with histologically proven Barrett's esophagus, seven of whom had evidence of low-grade dysplasia, underwent endoscopic treatment with topical delta-ALA." | 1.31 | Is topical delta-aminolevulinic acid adequate for photodynamic therapy in Barrett's esophagus? A pilot study. ( Dietel, M; Ebert, B; Fleige, B; Liebetruth, J; Lochs, H; Ortner, M-; Zumbusch, K, 2002) |
| "It will be the aim of further investigations to verify the optimal time of incubation and dosing of systemical 5-ALA application to enhance fluorescence contrasts and set the basis for fluorescence guided resections." | 1.31 | [Fluorescence staining of oral and laryngeal cancer after application of 5-aminolevulinic acid]. ( Baumgartner, R; Betz, CS; Heinrich, P; Janda, P; Leunig, A, 2002) |
| "Eight patients with Barrett's esophagus and/or early cancer were treated." | 1.31 | [Photodynamic therapy of dysplasias and early carcinomas in Barrett esophagus with a diode laser system--a pilot study]. ( Apel, D; Arnold, JC; Jakobs, R; Riemann, JF; Rosenbaum, A; Zöpf, T, 2001) |
| "Surveillance of patients with Barrett's esophagus or ulcerative colitis for dysplasia is confined to biopsy specimens taken randomly during endoscopy because dysplasia remains undetectable by visual inspection." | 1.30 | Endoscopic fluorescence detection of dysplasia in patients with Barrett's esophagus, ulcerative colitis, or adenomatous polyps after 5-aminolevulinic acid-induced protoporphyrin IX sensitization. ( Bäumler, W; Holstege, A; Knüchel, R; Messmann, H; Schölmerich, J, 1999) |
| "Following transurethral resection of bladder cancer, the fate of patients is clearly related to the presence or absence of precancerous or malignant lesions in the remaining mucosa." | 1.29 | [Photodynamic diagnosis of urothelial neoplasms after intravesicular instillation of 5-aminolevulinic acid]. ( Baumgartner, R; Ehsan, A; Hofstädter, F; Hofstetter, A; Knüchel, R; Kriegmair, M; Lumper, W; Steinbach, P, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 18 (16.22) | 18.2507 |
| 2000's | 53 (47.75) | 29.6817 |
| 2010's | 29 (26.13) | 24.3611 |
| 2020's | 11 (9.91) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, X | 4 |
| Yuan, Z | 1 |
| Tao, A | 1 |
| Wang, P | 1 |
| Xie, W | 1 |
| Yang, S | 1 |
| Huang, J | 1 |
| Wen, N | 1 |
| Han, Q | 1 |
| Wu, Z | 1 |
| Guo, H | 1 |
| Zhang, X | 1 |
| Mendonca, P | 1 |
| Sunny, SP | 1 |
| Mohan, U | 1 |
| Birur N, P | 1 |
| Suresh, A | 1 |
| Kuriakose, MA | 1 |
| Che, Q | 1 |
| Huang, X | 1 |
| Li, C | 1 |
| Li, J | 1 |
| Jiang, L | 1 |
| Zeng, K | 1 |
| Jin, JQ | 1 |
| Wang, Q | 2 |
| Zhang, YX | 1 |
| Lu, ZY | 1 |
| Li, BW | 1 |
| Wu, M | 1 |
| Liao, C | 1 |
| Zhao, Z | 1 |
| Zhou, Z | 1 |
| Liu, Y | 1 |
| Zhang, G | 1 |
| Wu, D | 1 |
| Wang, S | 1 |
| Zuo, M | 1 |
| Zhang, M | 1 |
| Li, D | 1 |
| Chen, W | 1 |
| Sha, M | 1 |
| Yuan, L | 1 |
| Qin, N | 1 |
| Jin, X | 1 |
| Xu, H | 1 |
| Deng, J | 1 |
| Dan, H | 1 |
| Ji, P | 1 |
| Chen, Q | 1 |
| Zeng, X | 1 |
| Lai, M | 1 |
| Pampena, R | 1 |
| Cornacchia, L | 1 |
| Pellacani, G | 1 |
| Peris, K | 1 |
| Longo, C | 1 |
| Andreadis, D | 1 |
| Pavlou, A- | 1 |
| Vakirlis, E | 1 |
| Anagnostou, E | 1 |
| Vrani, F | 1 |
| Poulopoulos, A | 1 |
| Kolokotronis, A | 1 |
| Ioannidis, D | 1 |
| Sotiriou, E | 1 |
| Paasch, U | 1 |
| Said, T | 1 |
| Miola, AC | 1 |
| Ferreira, ER | 1 |
| Abbade, LPF | 1 |
| Schmitt, JV | 1 |
| Miot, HA | 1 |
| Jurczyszyn, K | 1 |
| Kazubowska, K | 1 |
| Kubasiewicz-Ross, P | 1 |
| Ziółkowski, P | 1 |
| Dominiak, M | 1 |
| Calzavara-Pinton, P | 1 |
| Tanova, N | 1 |
| Hamon, P | 1 |
| Reinhold, U | 1 |
| Petering, H | 1 |
| Dirschka, T | 1 |
| Rozsondai, A | 1 |
| Gille, J | 1 |
| Kurzen, H | 1 |
| Ostendorf, R | 1 |
| Ebeling, A | 1 |
| Stocker, M | 1 |
| Radny, P | 1 |
| Wang, YY | 1 |
| Chen, YK | 1 |
| Hu, CS | 1 |
| Xiao, LY | 1 |
| Huang, WL | 1 |
| Chi, TC | 1 |
| Cheng, KH | 1 |
| Wang, YM | 1 |
| Yuan, SF | 1 |
| Basset-Seguin, N | 1 |
| Yang, DF | 4 |
| Lee, JW | 4 |
| Chen, HM | 6 |
| Huang, Z | 2 |
| Hsu, YC | 4 |
| Dixon, AJ | 1 |
| Anderson, SJ | 1 |
| Mazzurco, JD | 1 |
| Steinman, HK | 1 |
| Chen, JH | 1 |
| Chiang, CP | 6 |
| Liu, CJ | 1 |
| Chang, JL | 1 |
| Yazdani Abyaneh, MA | 1 |
| Falto-Aizpurua, L | 1 |
| Griffith, RD | 1 |
| Nouri, K | 1 |
| Yeh, SC | 1 |
| Sahli, S | 1 |
| Andrews, DW | 1 |
| Patterson, MS | 1 |
| Armstrong, D | 1 |
| Provias, J | 1 |
| Fang, Q | 1 |
| Ahn, PH | 1 |
| Quon, H | 1 |
| O'Malley, BW | 1 |
| Weinstein, G | 1 |
| Chalian, A | 1 |
| Malloy, K | 1 |
| Atkins, JH | 1 |
| Sollecito, T | 1 |
| Greenberg, M | 1 |
| McNulty, S | 1 |
| Lin, A | 1 |
| Zhu, TC | 1 |
| Finlay, JC | 1 |
| Cengel, K | 1 |
| Livolsi, V | 1 |
| Feldman, M | 1 |
| Mick, R | 1 |
| Busch, TM | 1 |
| Lima, CA | 1 |
| Goulart, VP | 1 |
| Correa, L | 1 |
| Zezell, DM | 1 |
| Wang, XL | 1 |
| Wang, HW | 1 |
| Guo, MX | 1 |
| Xu, SZ | 1 |
| Kleinpenning, MM | 1 |
| van de Kerkhof, PC | 1 |
| Gerritsen, RM | 1 |
| Watanabe, K | 1 |
| Hida, N | 1 |
| Ajioka, Y | 1 |
| Hori, K | 1 |
| Kamata, N | 1 |
| Sogawa, M | 1 |
| Yamagami, H | 1 |
| Tominaga, K | 1 |
| Watanabe, T | 1 |
| Fujiwara, Y | 1 |
| Matsumoto, T | 1 |
| Arakawa, T | 1 |
| Liutkeviciūte-Navickiene, J | 1 |
| Mordas, A | 1 |
| Simkute, S | 1 |
| Bloznelyte-Plesniene, L | 1 |
| Tyrrell, JS | 2 |
| Campbell, SM | 2 |
| Curnow, A | 4 |
| Corti, MA | 1 |
| Mainetti, C | 1 |
| Lin, HP | 1 |
| Yu, CH | 3 |
| Yang, H | 2 |
| Wang, YP | 2 |
| Davila, ML | 1 |
| Tyrrell, J | 1 |
| Campbell, S | 1 |
| Daayana, S | 1 |
| Winters, U | 1 |
| Stern, PL | 1 |
| Kitchener, HC | 1 |
| Morton, C | 1 |
| Kraft, M | 1 |
| Betz, CS | 3 |
| Leunig, A | 3 |
| Arens, C | 3 |
| Togsverd-Bo, K | 1 |
| Lerche, CM | 1 |
| Philipsen, PA | 1 |
| Poulsen, T | 1 |
| Wulf, HC | 2 |
| Haedersdal, M | 1 |
| Blake, E | 1 |
| Allen, J | 1 |
| Thorn, C | 1 |
| Shore, A | 1 |
| Tseng, MK | 1 |
| Kelleher, DK | 1 |
| Piazena, H | 1 |
| Ortner, M- | 1 |
| Zumbusch, K | 2 |
| Liebetruth, J | 1 |
| Ebert, B | 2 |
| Fleige, B | 2 |
| Dietel, M | 2 |
| Lochs, H | 3 |
| Zaak, D | 2 |
| Hungerhuber, E | 2 |
| Schneede, P | 1 |
| Stepp, H | 3 |
| Frimberger, D | 1 |
| Corvin, S | 1 |
| Schmeller, N | 1 |
| Kriegmair, M | 2 |
| Hofstetter, A | 3 |
| Knuechel, R | 2 |
| Knöchel, R | 1 |
| Zheng, W | 2 |
| Soo, KC | 2 |
| Sivanandan, R | 1 |
| Olivo, M | 2 |
| Brand, S | 2 |
| Wang, TD | 1 |
| Schomacker, KT | 1 |
| Poneros, JM | 1 |
| Lauwers, GY | 1 |
| Compton, CC | 1 |
| Pedrosa, MC | 1 |
| Nishioka, NS | 2 |
| Heinrich, P | 1 |
| Janda, P | 1 |
| Baumgartner, R | 5 |
| Ortner, MA | 1 |
| Hein, E | 1 |
| Nolte, D | 1 |
| Sukowski, U | 1 |
| Weber-Eibel, J | 1 |
| Stolte, M | 4 |
| Oberhuber, G | 1 |
| Porschen, R | 1 |
| Klump, B | 1 |
| Hörtnagl, H | 1 |
| Rinneberg, H | 1 |
| Csanády, M | 1 |
| Kiss, JG | 1 |
| Iván, L | 1 |
| Jóri, J | 1 |
| Czigner, J | 1 |
| Marcus, L | 1 |
| Silapunt, S | 1 |
| Goldberg, LH | 1 |
| Alam, M | 1 |
| Akoel, KM | 1 |
| Welfel, J | 1 |
| Gottwald, L | 1 |
| Suzin, J | 1 |
| Yang, CH | 1 |
| Lee, JC | 1 |
| Chen, CH | 1 |
| Hui, CY | 1 |
| Hong, HS | 1 |
| Kuo, HW | 1 |
| van den Akker, JT | 1 |
| Holroyd, JA | 1 |
| Vernon, DI | 1 |
| Sterenborg, HJ | 1 |
| Brown, SB | 2 |
| Chen, CT | 1 |
| Kuo, MY | 1 |
| Kuo, YS | 1 |
| Lan, WH | 1 |
| Tsai, T | 3 |
| Stiefelhagen, P | 1 |
| Endlicher, E | 3 |
| Messmann, H | 6 |
| Podda, M | 1 |
| Gelbmann, CM | 1 |
| Knüchel, R | 4 |
| Fürst, A | 1 |
| Szeimies, RM | 3 |
| Gölder, SK | 1 |
| Schölmerich, J | 3 |
| Lottner, C | 1 |
| Dragieva, G | 1 |
| Schärer, L | 1 |
| Dummer, R | 1 |
| Kempf, W | 1 |
| Nowakowski, Z | 1 |
| Stelmachów, J | 1 |
| Spiewankiewicz, B | 1 |
| Gerulewicz, G | 1 |
| Pech, O | 1 |
| Gossner, L | 4 |
| May, A | 4 |
| Rabenstein, T | 1 |
| Vieth, M | 1 |
| Berres, M | 1 |
| Ell, C | 4 |
| Tu, PC | 1 |
| Yeh, CY | 1 |
| Sharwani, A | 1 |
| Jerjes, W | 1 |
| Salih, V | 1 |
| MacRobert, AJ | 1 |
| El-Maaytah, M | 1 |
| Khalil, HS | 1 |
| Hopper, C | 1 |
| Pavel, S | 1 |
| Stender, I | 1 |
| Bakker-Wensveen, CA | 1 |
| Gilaberte, Y | 1 |
| Serra-Guillén, C | 1 |
| de las Heras, ME | 1 |
| Ruiz-Rodríguez, R | 1 |
| Fernández-Lorente, M | 1 |
| Benvenuto-Andrade, C | 1 |
| González-Rodríguez, S | 1 |
| Guillén-Barona, C | 1 |
| Ochsenkühn, T | 1 |
| Tillack, C | 1 |
| Diebold, J | 2 |
| Ott, SJ | 1 |
| Göke, B | 1 |
| Sackmann, M | 1 |
| Smolka, J | 1 |
| Mateasik, A | 1 |
| Cunderlikova, B | 1 |
| Sanislo, L | 1 |
| Mlkvy, P | 1 |
| Perrett, CM | 1 |
| McGregor, JM | 1 |
| Warwick, J | 1 |
| Karran, P | 1 |
| Leigh, IM | 1 |
| Proby, CM | 1 |
| Harwood, CA | 1 |
| Reussner, D | 1 |
| Woenkhaus, J | 1 |
| Glanz, H | 1 |
| Harvie, SE | 1 |
| Franco, RA | 1 |
| Rydell, R | 1 |
| Eker, C | 2 |
| Andersson-Engels, S | 2 |
| Krogdahl, A | 1 |
| Wahlberg, P | 1 |
| Svanberg, K | 2 |
| Mayinger, B | 2 |
| Neumann, F | 1 |
| Kastner, C | 1 |
| Degitz, K | 1 |
| Hahn, EG | 4 |
| Schwab, D | 1 |
| Hung, HY | 1 |
| Cheng, SJ | 1 |
| Korell, M | 2 |
| Untch, M | 2 |
| Abels, C | 1 |
| Dellian, M | 1 |
| Kirschstein, M | 1 |
| Beyer, W | 1 |
| Goetz, AE | 1 |
| Ehsan, A | 1 |
| Steinbach, P | 1 |
| Lumper, W | 1 |
| Hofstädter, F | 1 |
| Sroka, R | 2 |
| Rick, K | 1 |
| Ortner, M | 1 |
| Hauser, T | 1 |
| Kullmann, F | 1 |
| Bäumler, W | 2 |
| Hinnen, P | 1 |
| de Rooij, FW | 1 |
| van Velthuysen, ML | 1 |
| Edixhoven, A | 1 |
| van Hillegersberg, R | 2 |
| Tilanus, HW | 1 |
| Wilson, JH | 1 |
| Siersema, PD | 2 |
| Grob, M | 1 |
| Schmid-Grendelmeier, P | 1 |
| Petrík, R | 2 |
| Jirsa, M | 2 |
| Dvorák, E | 2 |
| Skoda, V | 2 |
| Stádník, B | 2 |
| Holstege, A | 1 |
| Montán, S | 1 |
| Jaramillo, E | 1 |
| Koizumi, K | 1 |
| Rubio, C | 1 |
| Svanberg, S | 1 |
| Slezak, P | 1 |
| Ma, G | 1 |
| Ikeda, H | 1 |
| Inokuchi, T | 1 |
| Sano, K | 1 |
| Orth, K | 1 |
| Stanescu, A | 1 |
| Rück, A | 1 |
| Russ, D | 1 |
| Beger, HG | 1 |
| Reh, H | 1 |
| Hochberger, J | 1 |
| Keller, R | 1 |
| Fischbach, W | 1 |
| van den Boogert, J | 1 |
| van Staveren, HJ | 1 |
| de Bruin, RW | 1 |
| Eikelaar, JH | 1 |
| Hillemanns, P | 1 |
| Dannecker, C | 1 |
| Weingandt, H | 1 |
| Pröve, F | 1 |
| Itoh, Y | 1 |
| Ninomiya, Y | 1 |
| Henta, T | 1 |
| Tajima, S | 1 |
| Ishibashi, A | 1 |
| Zöpf, T | 1 |
| Rosenbaum, A | 1 |
| Apel, D | 1 |
| Jakobs, R | 1 |
| Arnold, JC | 1 |
| Riemann, JF | 1 |
| Morton, CA | 2 |
| Sieron, A | 1 |
| Namyslowski, G | 1 |
| Misiolek, M | 1 |
| Adamek, M | 1 |
| Kawczyk-Krupka, A | 1 |
| Karrer, S | 1 |
| Hohenleutner, U | 1 |
| Landthaler, M | 1 |
| Cappugi, P | 1 |
| Campolmi, P | 1 |
| Mavilia, L | 1 |
| Prignano, F | 1 |
| Rossi, R | 1 |
| Hartmann, A | 1 |
| Schlake, G | 1 |
| Hofstaedter, F | 1 |
| Eisendrath, P | 1 |
| Van Laethem, JL | 1 |
| Fehr, MK | 1 |
| Hornung, R | 1 |
| Degen, A | 1 |
| Schwarz, VA | 1 |
| Fink, D | 1 |
| Haller, U | 1 |
| Wyss, P | 1 |
| Collins, S | 1 |
| Ibbotson, S | 1 |
| Jenkinson, H | 1 |
| Kurwa, H | 1 |
| Langmack, K | 1 |
| McKenna, K | 1 |
| Moseley, H | 1 |
| Pearse, AD | 1 |
| Stringer, M | 1 |
| Taylor, DK | 1 |
| Wong, G | 1 |
| Rhodes, LE | 1 |
| Hellmig, S | 1 |
| Fölsch, UR | 1 |
| Jin, J | 1 |
| Li, W | 1 |
| Han, Y | 1 |
| Liu, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Indoor Daylight Photo Dynamic Therapy (PDT) for Actinic Keratosis[NCT03805737] | 43 participants (Actual) | Interventional | 2019-11-01 | Completed | |||
| Portable Measurement of Protoporphyrin IX in the Skin[NCT04223570] | 218 participants (Anticipated) | Observational | 2022-12-01 | Enrolling by invitation | |||
| The Correlation of Surgical Colorectal Cancer Specimen Pathology With the Fluorescence of Photodynamic Diagnostics (PDD): a Clinical Pilot Study[NCT03272659] | Phase 2 | 0 participants (Actual) | Interventional | 2018-04-01 | Withdrawn (stopped due to Long process and due to strict deadline, project was stopped.) | ||
| [NCT01344902] | Phase 1/Phase 2 | 13 participants (Actual) | Interventional | 2009-02-28 | Terminated (stopped due to The study was stopped due to inadequate efficacy after 13 patients were evaluated.) | ||
| A Randomized Half-side Comparative Trial of Fractional Laser-assisted Daylight Photodynamic Therapy Versus Daylight Photodynamic Therapy in Organ Transplant Recipients With Multiple Actinic Keratoses of the Scalp or Forehead[NCT01898936] | 12 participants (Actual) | Interventional | 2013-08-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
19 reviews available for aminolevulinic acid and Precancerous Conditions
| Article | Year |
|---|---|
Non-invasive imaging of oral potentially malignant and malignant lesions: A systematic review and meta-analysis.
Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Humans; Mouth Diseases; Mouth Neoplasms; Narrow Band | 2022 |
Photodynamic therapy for oral potentially malignant disorders.
Topics: Aminolevulinic Acid; Humans; Lasers, Semiconductor; Methylene Blue; Mouth Diseases; Mouth Neoplasms; | 2019 |
Treatments of actinic cheilitis: A systematic review of the literature.
Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Cheilitis; Combined Modality Therapy; Dermabrasion; D | 2020 |
[PDT panoramic view. Principle, photosensitizers, light sources and validated indications in dermatology].
Topics: Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Clinical Trials as Topic; Humans; Kerat | 2013 |
Photodynamic therapy for actinic cheilitis: a systematic review.
Topics: Aminolevulinic Acid; Cheilitis; Esthetics; Humans; Pain; Photochemotherapy; Photosensitizing Agents; | 2015 |
Photodynamic therapy.
Topics: Adenocarcinoma; Aminolevulinic Acid; Barrett Esophagus; Dihematoporphyrin Ether; Esophageal Neoplasm | 2011 |
Clinical and immunological response to photodynamic therapy in the treatment of vulval intraepithelial neoplasia.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Female; Humans; Papillomaviridae; Papillomavirus Infections; | 2011 |
Value of fluorescence endoscopy for the early diagnosis of laryngeal cancer and its precursor lesions.
Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Early Detection of Cancer; Endoscopy; Fluorescence; H | 2011 |
Topical and light-based treatments for actinic keratoses.
Topics: Adjuvants, Immunologic; Administration, Topical; Aminolevulinic Acid; Aminoquinolines; Antineoplasti | 2003 |
Photodynamic diagnosis in the gastrointestinal tract.
Topics: Aminolevulinic Acid; Endoscopy, Gastrointestinal; Fluorescence; Gastrointestinal Neoplasms; Humans; | 2004 |
Photodynamic therapy--a new treatment option for epithelial malignancies of the skin.
Topics: Aminolevulinic Acid; Humans; Neoplasms, Glandular and Epithelial; Photochemotherapy; Precancerous Co | 2004 |
[Photodynamic therapy in dermatology].
Topics: Aminolevulinic Acid; Esthetics; Forecasting; Humans; Infrared Rays; Low-Level Light Therapy; Photoch | 2006 |
Aminolevulinic acid and photodynamic combination therapy in the treatment of actinic keratoses: caring for the patient.
Topics: Aminolevulinic Acid; Heme; Humans; Keratosis; Nurse's Role; Nursing Assessment; Photochemotherapy; P | 2007 |
[Topical photodynamic therapy in dermatology].
Topics: Aminolevulinic Acid; Humans; Photochemotherapy; Precancerous Conditions; Skin Neoplasms; Treatment O | 1998 |
[Fluorescence endoscopy in gastroenterology].
Topics: Aminolevulinic Acid; Barrett Esophagus; Colitis, Ulcerative; Colonic Neoplasms; Endoscopy, Gastroint | 2000 |
5-Aminolevulinic acid-induced protoporphyrin IX for the detection of gastrointestinal dysplasia.
Topics: Aminolevulinic Acid; Animals; Endoscopy, Gastrointestinal; Gastrointestinal Neoplasms; Humans; Intes | 2000 |
Role of lasers and photodynamic therapy in the treatment of cutaneous malignancy.
Topics: Aged; Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Clinica | 2001 |
Topical 5-aminolevulinic acid and photodynamic therapy in dermatology: a minireview.
Topics: Administration, Topical; Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Clinical Trial | 2001 |
Guidelines for topical photodynamic therapy: report of a workshop of the British Photodermatology Group.
Topics: Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Health Care Costs; Humans; Keratosis; L | 2002 |
12 trials available for aminolevulinic acid and Precancerous Conditions
| Article | Year |
|---|---|
Daylight photodynamic therapy for the management of actinic cheilitis.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Squamous Cell; Cheilitis; Female; Follow-Up | 2020 |
Novel photodynamic therapy does not prevent new skin cancers--randomized controlled trial.
Topics: Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Facial Neoplasms; Female | 2014 |
Toxicities and early outcomes in a phase 1 trial of photodynamic therapy for premalignant and early stage head and neck tumors.
Topics: Aged; Aminolevulinic Acid; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; | 2016 |
Protoporphyrin IX photobleaching during the light irradiation phase of standard dermatological methyl-aminolevulinate photodynamic therapy.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Male; Photobleaching; Photochemotherap | 2010 |
Comparison of protoporphyrin IX accumulation and destruction during methylaminolevulinate photodynamic therapy of skin tumours located at acral and nonacral sites.
Topics: Adult; Aged; Aminolevulinic Acid; Analysis of Variance; Extremities; Facial Dermatoses; Female; Fluo | 2011 |
Comparison of protoporphyrin IX accumulation and destruction during methylaminolevulinate photodynamic therapy of skin tumours located at acral and nonacral sites.
Topics: Adult; Aged; Aminolevulinic Acid; Analysis of Variance; Extremities; Facial Dermatoses; Female; Fluo | 2011 |
Comparison of protoporphyrin IX accumulation and destruction during methylaminolevulinate photodynamic therapy of skin tumours located at acral and nonacral sites.
Topics: Adult; Aged; Aminolevulinic Acid; Analysis of Variance; Extremities; Facial Dermatoses; Female; Fluo | 2011 |
Comparison of protoporphyrin IX accumulation and destruction during methylaminolevulinate photodynamic therapy of skin tumours located at acral and nonacral sites.
Topics: Adult; Aged; Aminolevulinic Acid; Analysis of Variance; Extremities; Facial Dermatoses; Female; Fluo | 2011 |
Effect of an oxygen pressure injection (OPI) device on the oxygen saturation of patients during dermatological methyl aminolevulinate photodynamic therapy.
Topics: Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Humans; Keratosis, Actinic; Oxygen; Pho | 2013 |
Fluorescence spectroscopy combined with 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in detecting oral premalignancy.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Humans; Middle Aged; Mouth Neoplasms; P | 2006 |
Topical photodynamic therapy for prevention of new skin lesions in renal transplant recipients.
Topics: Administration, Topical; Adult; Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Female; Humans; Im | 2006 |
In vivo fluorescence diagnostics and photodynamic therapy of gastrointestinal superficial polyps with aminolevulinic acid. A clinical and spectroscopic study.
Topics: Aminolevulinic Acid; Endoscopy, Gastrointestinal; Esophageal Diseases; Female; Humans; Intestinal Po | 2006 |
Treatment of post-transplant premalignant skin disease: a randomized intrapatient comparative study of 5-fluorouracil cream and topical photodynamic therapy.
Topics: Administration, Topical; Aged; Aminolevulinic Acid; Antimetabolites, Antineoplastic; Bowen's Disease | 2007 |
Photodynamic therapy of vulvar intraepithelial neoplasia using 5-aminolevulinic acid.
Topics: Adult; Aged; Aminolevulinic Acid; Carcinoma in Situ; Female; Humans; Middle Aged; Photochemotherapy; | 2000 |
Topical delta-aminolevulinic acid-based photodynamic therapy for Japanese actinic keratoses.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Arm; Asian People; Carcinoma, Squamous Cell; Facial De | 2000 |
80 other studies available for aminolevulinic acid and Precancerous Conditions
| Article | Year |
|---|---|
Hydrogel-based patient-friendly photodynamic therapy of oral potentially malignant disorders.
Topics: Aminolevulinic Acid; Animals; Cricetinae; Humans; Hydrogels; Photochemotherapy; Photosensitizing Age | 2022 |
Efficacy and safety of photodynamic therapy mediatied by 5-aminolevulinic acid for the treatment of vaginal high-grade intraepithelial lesions.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Female; Humans; Papillomaviridae; Papillomavirus Infections; | 2022 |
Effectiveness of photodynamic therapy with 5-aminolevulinic acid for Bowenoid papulosis: A retrospective study with long-term follow-up.
Topics: Adolescent; Aminolevulinic Acid; Carcinoma, Squamous Cell; Condylomata Acuminata; Follow-Up Studies; | 2022 |
Effect of ALA-PDT on inhibition of oral precancerous cell growth and its related mechanisms.
Topics: Aminolevulinic Acid; Carcinogenesis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Humans; Photo | 2022 |
Local narrow margin excision sequential with modified ALA-PDT for successful treatment of an 86-year-old patient with malignant proliferating trichilemmal tumor.
Topics: Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Photochemotherapy; Photosensitizing Agents; | 2023 |
Er: YAG laser assisted photodynamic therapy for the management of severe oral epithelial dysplasia with innate and adaptive immune responses.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Humans; Immunity; Laser Therapy; Lasers, Solid-State; Photoc | 2023 |
Treating Field Cancerization by Ablative Fractional Laser and Indoor Daylight: Assessment of Efficacy and Tolerability.
Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Aminolevulinic Acid; Combined Modality Therapy; | 2020 |
Randomized clinical trial testing the efficacy and safety of 0.5% colchicine cream versus photodynamic therapy with methyl aminolevulinate in the treatment of skin field cancerization: study protocol.
Topics: Aminolevulinic Acid; Clinical Protocols; Colchicine; Humans; Keratosis, Actinic; Photochemotherapy; | 2018 |
Application of fractal dimension analysis and photodynamic diagnosis in the case of differentiation between lichen planus and leukoplakia: A preliminary study.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Fractals; Humans; Leuk | 2018 |
Evaluation of the treatment costs and duration of topical treatments for multiple actinic keratosis based on the area of the cancerization field and not on the number of lesions.
Topics: Administration, Topical; Aminolevulinic Acid; Cohort Studies; Cost of Illness; Diclofenac; Diterpene | 2019 |
Photodynamic therapy with a 5-ALA patch does not increase the risk of conversion of actinic keratoses into squamous cell carcinoma: Results of a multicentre non-interventional study.
Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Disease Progression; DNA Damage; Humans; Keratosis, A | 2018 |
MAL-PDT inhibits oral precancerous cells and lesions via autophagic cell death.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminolevulinic Acid; Animals; Autophagosomes; Autophagy; Body Weig | 2019 |
Methotrexate enhances 5-aminolevulinic acid-mediated photodynamic therapy-induced killing of human SCC4 cells by upregulation of coproporphyrinogen oxidase.
Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Coproporphyrinogen Oxidase; Humans; Methotrexate; Mou | 2014 |
Topical methotrexate pretreatment enhances the therapeutic effect of topical 5-aminolevulinic acid-mediated photodynamic therapy on hamster buccal pouch precancers.
Topics: Administration, Topical; Aminolevulinic Acid; Animals; Cricetinae; Immunosuppressive Agents; Male; M | 2014 |
Improve efficacy of topical ALA-PDT by calcipotriol through up-regulation of coproporphyrinogen oxidase.
Topics: Administration, Topical; Aminolevulinic Acid; Animals; Calcitriol; Cell Line, Tumor; Cheek; Cricetin | 2014 |
5-Aminolevulinic acid induced protoporphyrin IX as a fluorescence marker for quantitative image analysis of high-grade dysplasia in Barrett's esophagus cellular models.
Topics: Adenocarcinoma; Algorithms; Aminolevulinic Acid; Barrett Esophagus; Biomarkers; Esophageal Neoplasms | 2015 |
Using Fourier transform infrared spectroscopy to evaluate biological effects induced by photodynamic therapy.
Topics: Aminolevulinic Acid; Animals; Biomarkers, Tumor; Carcinoma, Squamous Cell; Discriminant Analysis; Fe | 2016 |
Treatment of skin cancer and pre-cancer using topical ALA-PDT--a single hospital experience.
Topics: Administration, Topical; Adult; Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Carcinoma, Squamou | 2008 |
The clinical efficacy of topical methyl-aminolevulinate photodynamic therapy in moderate to severe actinic keratoses of the face and scalp.
Topics: Administration, Topical; Aged; Aged, 80 and over; Aminolevulinic Acid; Analysis of Variance; Carcino | 2010 |
Photodynamic diagnosis of endoscopically invisible flat dysplasia in patients with ulcerative colitis by visualization using local 5-aminolevulinic acid-induced photosensitization.
Topics: Adult; Aged; Aminolevulinic Acid; Colitis, Ulcerative; Colonoscopy; Humans; Male; Photosensitizing A | 2010 |
[Fluorescence diagnostics of skin tumors using 5-aminolevulinic acid and its methyl ester].
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell | 2009 |
The relationship between protoporphyrin IX photobleaching during real-time dermatological methyl-aminolevulinate photodynamic therapy (MAL-PDT) and subsequent clinical outcome.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Female; Humans | 2010 |
Methylaminolevulinic acid-based photodynamic therapy: the patient's view.
Topics: Adult; Aged; Aminolevulinic Acid; Chi-Square Distribution; Female; Follow-Up Studies; Humans; Male; | 2010 |
Topical photodynamic therapy is very effective for oral verrucous hyperplasia and oral erythroleukoplakia.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma in Situ; Erythroplasia; Femal | 2010 |
Porphyrin biodistribution in UV-exposed murine skin after methyl- and hexyl-aminolevulinate incubation.
Topics: Administration, Topical; Aminolevulinic Acid; Animals; Biological Availability; Female; Humans; Mice | 2012 |
Successful treatment of 7,12-dimethylbenz(a)anthracene-induced hamster buccal pouch precancerous lesions by topical 5-aminolevulinic acid-mediated photodynamic therapy.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminolevulinic Acid; Animals; Cheek; Cricetinae; Male; Mesocricetu | 2012 |
The interpretation of clinical studies on the photodynamic treatment of actinic keratosis.
Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Clinical Trials as Topic; Humans; Keratosis, Actinic; | 2012 |
Is topical delta-aminolevulinic acid adequate for photodynamic therapy in Barrett's esophagus? A pilot study.
Topics: Aminolevulinic Acid; Barrett Esophagus; Esophageal Neoplasms; Female; Humans; Male; Middle Aged; Pho | 2002 |
Role of 5-aminolevulinic acid in the detection of urothelial premalignant lesions.
Topics: Aminolevulinic Acid; Biomarkers, Tumor; Biopsy; Carcinoma in Situ; Carcinoma, Transitional Cell; End | 2002 |
Detection of squamous cell carcinomas and pre-cancerous lesions in the oral cavity by quantification of 5-aminolevulinic acid induced fluorescence endoscopic images.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Aminolevulinic Acid; Carcinoma, Squamous Cell; Diagnosti | 2002 |
Detection of high-grade dysplasia in Barrett's esophagus by spectroscopy measurement of 5-aminolevulinic acid-induced protoporphyrin IX fluorescence.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Esophageal Neoplasms; Esopha | 2002 |
[Fluorescence staining of oral and laryngeal cancer after application of 5-aminolevulinic acid].
Topics: Administration, Inhalation; Administration, Oral; Aminolevulinic Acid; Biopsy; Carcinoma, Squamous C | 2002 |
Time gated fluorescence spectroscopy in Barrett's oesophagus.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Biomarkers, | 2003 |
[An unsurpassed duo in control of skin cancer. Metvix and Aktilite].
Topics: Administration, Topical; Aminolevulinic Acid; Carcinoma, Basal Cell; Cell Survival; Hematoporphyrin | 2003 |
ALA (5-aminolevulinic acid)-induced protoporphyrin IX fluorescence in the endoscopic diagnostic and control of pharyngo-laryngeal cancer.
Topics: Adult; Aged; Aminolevulinic Acid; Diagnosis, Differential; Female; Fluorescence; Humans; Laryngeal N | 2004 |
Photodynamic therapy for actinic keratosis followed by 5-fluorouracil reaction.
Topics: Aminolevulinic Acid; Antimetabolites, Antineoplastic; Emollients; Female; Fluorouracil; Humans; Kera | 2003 |
[Photodynamic diagnosis of vulvar precancerous conditions and invasive cancers using 5-aminolevulinic acid].
Topics: Aminolevulinic Acid; Carcinoma in Situ; Diagnostic Techniques, Obstetrical and Gynecological; Female | 2003 |
Photodynamic therapy for bowenoid papulosis using a novel incoherent light-emitting diode device.
Topics: Adult; Aminolevulinic Acid; Bowen's Disease; Electronics; Humans; Male; Penile Neoplasms; Photochemo | 2003 |
Chronic UVB exposure enhances in vitro percutaneous penetration of 5-aminulevulinic acid in hairless mouse skin.
Topics: Aminolevulinic Acid; Animals; Disease Models, Animal; Female; In Vitro Techniques; Mice; Mice, Hairl | 2004 |
Successful treatment of oral verrucous hyperplasia with topical 5-aminolevulinic acid-mediated photodynamic therapy.
Topics: Adult; Aminolevulinic Acid; Humans; Hyperplasia; Male; Middle Aged; Mouth Diseases; Mouth Neoplasms; | 2004 |
The use of digitized endoscopic imaging of 5-ALA-induced PPIX fluorescence to detect and diagnose oral premalignant and malignant lesions in vivo.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Diagnostic Imaging; Endoscopy; Female; Fluoresc | 2004 |
[In actinic keratosis and basal cell carcinoma. The power of light heals without scars].
Topics: Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Humans; Keratosis; Middle Aged; Ointments; Photoch | 2003 |
[Eliminating light-induced skin cancer without operation].
Topics: Administration, Topical; Aminolevulinic Acid; Carcinoma, Basal Cell; Hematoporphyrin Photoradiation; | 2004 |
Hexaminolevulinate-induced fluorescence endoscopy in patients with rectal adenoma and cancer: a pilot study.
Topics: Adenoma; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma in Situ; Cell Transformatio | 2004 |
[Early diagnosis of laryngeal cancer].
Topics: Aminolevulinic Acid; Diagnosis, Differential; Early Diagnosis; Fluorescence; Humans; Laryngeal Neopl | 2004 |
Diagnostic value of the PDD method in evaluation of vulvar lesions.
Topics: Adult; Aged; Aminolevulinic Acid; Female; Humans; Microscopy; Middle Aged; Photochemotherapy; Photos | 2005 |
Long-term results of photodynamic therapy with 5-aminolevulinic acid for superficial Barrett's cancer and high-grade intraepithelial neoplasia.
Topics: Adenocarcinoma; Aged; Aminolevulinic Acid; Barrett Esophagus; Disease-Free Survival; Esophageal Neop | 2005 |
Successful treatment of oral verrucous hyperplasia and oral leukoplakia with topical 5-aminolevulinic acid-mediated photodynamic therapy.
Topics: Administration, Topical; Adult; Aged; Aminolevulinic Acid; Carcinoma, Verrucous; Drug Administration | 2005 |
Low frequency of colorectal dysplasia in patients with long-standing inflammatory bowel disease colitis: detection by fluorescence endoscopy.
Topics: Administration, Oral; Adult; Aged; Aminolevulinic Acid; Biopsy; Colitis; Colonoscopy; Colorectal Neo | 2006 |
Indirect fluorescence laryngoscopy in the diagnosis of precancerous and cancerous laryngeal lesions.
Topics: Aminolevulinic Acid; Diagnosis, Differential; Fluorescence; Humans; Hyperplasia; Laryngeal Diseases; | 2007 |
Aminolevulinic acid 585 nm pulsed dye laser photodynamic treatment of laryngeal keratosis with atypia.
Topics: Administration, Topical; Aged; Ambulatory Care; Aminolevulinic Acid; Biopsy; Cell Transformation, Ne | 2007 |
Fluorescence investigations to classify malignant laryngeal lesions in vivo.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma; Female; Humans; Laryngeal Ne | 2008 |
Early detection of premalignant conditions in the colon by fluorescence endoscopy using local sensitization with hexaminolevulinate.
Topics: Aged; Aminolevulinic Acid; Biopsy, Needle; Colonic Neoplasms; Colonic Polyps; Colonoscopy; Early Dia | 2008 |
Early detection of premalignant conditions in the colon by fluorescence endoscopy using local sensitization with hexaminolevulinate.
Topics: Aged; Aminolevulinic Acid; Biopsy, Needle; Colonic Neoplasms; Colonic Polyps; Colonoscopy; Early Dia | 2008 |
Early detection of premalignant conditions in the colon by fluorescence endoscopy using local sensitization with hexaminolevulinate.
Topics: Aged; Aminolevulinic Acid; Biopsy, Needle; Colonic Neoplasms; Colonic Polyps; Colonoscopy; Early Dia | 2008 |
Early detection of premalignant conditions in the colon by fluorescence endoscopy using local sensitization with hexaminolevulinate.
Topics: Aged; Aminolevulinic Acid; Biopsy, Needle; Colonic Neoplasms; Colonic Polyps; Colonoscopy; Early Dia | 2008 |
Photodynamic therapy outcome for oral verrucous hyperplasia depends on the clinical appearance, size, color, epithelial dysplasia, and surface keratin thickness of the lesion.
Topics: Administration, Topical; Adult; Aged; Aminolevulinic Acid; Carcinoma, Verrucous; Female; Humans; Hyp | 2008 |
[Use of photodynamic laser therapy in gynecology].
Topics: Adult; Aged; Aminolevulinic Acid; Female; Follow-Up Studies; Genital Neoplasms, Female; Genitalia, F | 1995 |
[Photodynamic diagnosis of urothelial neoplasms after intravesicular instillation of 5-aminolevulinic acid].
Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma | 1994 |
Photodynamic ablation of high-grade dysplasia and early cancer in Barrett's esophagus by means of 5-aminolevulinic acid.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Esophageal Neoplasms; Female | 1998 |
Drug, light, and oxygen: a dynamic combination in the clinic.
Topics: Aminolevulinic Acid; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholangiocarcinoma; Esophageal N | 1998 |
[Photodynamic therapy of early squamous epithelial carcinomas and severe squamous epithelial dysplasias of the esophagus with 5-aminolevulinic acid].
Topics: Administration, Oral; Aged; Aminolevulinic Acid; Carcinoma, Squamous Cell; Esophageal Neoplasms; Eso | 1998 |
[Eradication of high-grade dysplasia in Barrett esophagus by photodynamic therapy with endogenously generated protoporphyrin IX].
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Esophageal Neoplasms; Esophagus; Fe | 1998 |
[Photodynamic diagnosis of gastrointestinal precancerous lesions after sensitization with 5-aminolevulinic acid. A pilot study].
Topics: Adenoma; Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Colitis, Ulcerative; Colorectal Neopla | 1998 |
Biochemical basis of 5-aminolaevulinic acid-induced protoporphyrin IX accumulation: a study in patients with (pre)malignant lesions of the oesophagus.
Topics: Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Esophageal Neoplasms; Esophagus; Female; Ferroc | 1998 |
[Fluorescence--endoscopy in carcinoma of the urinary bladder].
Topics: Aminolevulinic Acid; Cystoscopes; Humans; Neoplasm Recurrence, Local; Precancerous Conditions; Urina | 1998 |
Fluorescence cystoscopy in the diagnostics and treatment of bladder tumors.
Topics: Aminolevulinic Acid; Biopsy; Carcinoma in Situ; Carcinoma, Transitional Cell; Cystoscopes; Endoscope | 1998 |
Endoscopic fluorescence detection of dysplasia in patients with Barrett's esophagus, ulcerative colitis, or adenomatous polyps after 5-aminolevulinic acid-induced protoporphyrin IX sensitization.
Topics: Adenomatous Polyps; Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Biopsy; Colitis, Ulcerative | 1999 |
Clinical spectral characterisation of colonic mucosal lesions using autofluorescence and delta aminolevulinic acid sensitisation.
Topics: Adenoma; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Colon; Colonic Neoplasms; Colonoscopy; | 1999 |
Effect of photodynamic therapy using 5-aminolevulinic acid on 4-nitroquinoline-1-oxide-induced premalignant and malignant lesions of mouse tongue.
Topics: 4-Nitroquinoline-1-oxide; Aminolevulinic Acid; Animals; Carcinogens; Fluorescent Antibody Technique; | 1999 |
[Photodynamic ablation and argon-plasma coagulation of premalignant and early-stage malignant lesions of the oesophagus--an alternative to surgery?].
Topics: Aged; Aminolevulinic Acid; Argon; Barrett Esophagus; Carcinoma; Esophageal Neoplasms; Female; Humans | 1999 |
Endoscopic photodynamic diagnosis: oral aminolevulinic acid is a marker of GI cancer and dysplastic lesions.
Topics: Adenoma; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Duodenal Neoplasms; Endoscopy, Digesti | 1999 |
[Endoscopic fluorescence detection of dysplasia in patients with Barrett's esophagus, ulcerative colitis or colorectal adenomas].
Topics: Adenomatous Polyps; Aminolevulinic Acid; Barrett Esophagus; Biopsy; Colitis, Ulcerative; Colorectal | 1999 |
Photodynamic therapy for esophageal lesions: selectivity depends on wavelength, power, and light dose.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Esophageal Neoplasms; Esophagus; Hematoporph | 1999 |
[Photodynamic therapy of dysplasias and early carcinomas in Barrett esophagus with a diode laser system--a pilot study].
Topics: Adenocarcinoma; Aged; Aminolevulinic Acid; Barrett Esophagus; Cell Transformation, Neoplastic; Esoph | 2001 |
Topical photodynamic therapy in dermatology.
Topics: Administration, Topical; Aminolevulinic Acid; Facial Neoplasms; Hematoporphyrin Photoradiation; Huma | 2001 |
Photodynamic therapy of premalignant lesions and local recurrence of laryngeal and hypopharyngeal cancers.
Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Female; Humans; Hypopharyngeal Neoplasms; Laryngeal N | 2001 |
Occurrence of chromosome 9 and p53 alterations in multifocal dysplasia and carcinoma in situ of human urinary bladder.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Chromosome Aberrations; Chromosomes | 2002 |
Endoscopic fluorescence detection of low and high grade dysplasia in Barrett's oesophagus using systemic or local 5-aminolaevulinic acid sensitization.
Topics: Administration, Oral; Administration, Topical; Aminolevulinic Acid; Barrett Esophagus; Cell Transfor | 2002 |
Photodynamic therapy of vulvar and vaginal condyloma and intraepithelial neoplasia using topically applied 5-aminolevulinic acid.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aminolevulinic Acid; Condylomata Acuminata; Female | 2002 |
[Early detection of gastrointestinal tumors. Guided biopsy with fluorescence].
Topics: Aminolevulinic Acid; Biopsy; Diagnosis, Differential; Endoscopy, Gastrointestinal; Gastric Mucosa; G | 2002 |
[5-aminolevulinic acid induced fluorescence for the detection of oesophageal lesions].
Topics: Aminolevulinic Acid; Esophageal Neoplasms; Esophagoscopy; Esophagus; Fluorescence; Humans; Precancer | 2002 |
Differential in vitro sensitivity of oral precancerous and squamous cell carcinoma cell lines to 5-aminolevulinic acid-mediated photodynamic therapy.
Topics: Aminolevulinic Acid; Apoptosis; Carcinoma, Squamous Cell; Cell Line, Tumor; Dose-Response Relationsh | 2020 |