aminolevulinic acid has been researched along with Port-Wine Stain in 5 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
Port-Wine Stain: A vascular malformation of developmental origin characterized pathologically by ectasia of superficial dermal capillaries, and clinically by persistent macular erythema. In the past, port wine stains have frequently been termed capillary hemangiomas, which they are not; unfortunately this confusing practice persists: HEMANGIOMA, CAPILLARY is neoplastic, a port-wine stain is non-neoplastic. Port-wine stains vary in color from fairly pale pink to deep red or purple and in size from a few millimeters to many centimeters in diameter. The face is the most frequently affected site and they are most often unilateral. (From Rook et al., Textbook of Dermatology, 5th ed, p483)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effectiveness and safety of topical application of 5-aminolevulinic acid (ALA) followed by pulsed dye laser (PDL) irradiation for the treatment of recalcitrant port-wine stain (PWS)." | 9.16 | Topical application of 5-aminolevulinic acid followed by 595-nm pulsed dye laser irradiation for the treatment of recalcitrant port-wine stains: a primary study. ( Liu, S; Luo, D; Wang, Z; Yang, C; Yang, S; Zhang, X, 2012) |
| "To evaluate the effectiveness and safety of topical application of 5-aminolevulinic acid (ALA) followed by pulsed dye laser (PDL) irradiation for the treatment of recalcitrant port-wine stain (PWS)." | 5.16 | Topical application of 5-aminolevulinic acid followed by 595-nm pulsed dye laser irradiation for the treatment of recalcitrant port-wine stains: a primary study. ( Liu, S; Luo, D; Wang, Z; Yang, C; Yang, S; Zhang, X, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wen, X | 1 |
| Li, Y | 1 |
| Hamblin, MR | 1 |
| Huang, N | 1 |
| Zeng, J | 1 |
| Liang, J | 1 |
| Qiu, H | 1 |
| Wang, Y | 1 |
| Gu, Y | 1 |
| Li, W | 1 |
| Yamada, I | 1 |
| Masumoto, K | 1 |
| Ueda, Y | 1 |
| Hashimoto, K | 1 |
| Liu, S | 1 |
| Yang, C | 1 |
| Yang, S | 1 |
| Wang, Z | 1 |
| Luo, D | 1 |
| Zhang, X | 1 |
| Evans, AV | 1 |
| Robson, A | 1 |
| Barlow, RJ | 1 |
| Kurwa, HA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Treatment of Port-wine Mark in Sturge-Weber Syndrome Using Topical Timolol[NCT01533376] | Phase 1 | 3 participants (Actual) | Interventional | 2012-02-29 | Terminated | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for aminolevulinic acid and Port-Wine Stain
| Article | Year |
|---|---|
Photodynamic therapy in dermatology beyond non-melanoma cancer: An update.
Topics: Acne Vulgaris; Aminolevulinic Acid; Collagen; Humans; Photochemotherapy; Photosensitizing Agents; Po | 2017 |
3 trials available for aminolevulinic acid and Port-Wine Stain
| Article | Year |
|---|---|
A randomized, double-blind, placebo-controlled study of oral oxycodone plus acetaminophen for the treatment of pain in photodynamic therapy on port wine stains.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aminolevulinic Acid; Analgesics, Non-Narcoti | 2014 |
Topical application of 5-aminolevulinic acid followed by 595-nm pulsed dye laser irradiation for the treatment of recalcitrant port-wine stains: a primary study.
Topics: Administration, Cutaneous; Adolescent; Adult; Aminolevulinic Acid; Child; Cosmetic Techniques; Femal | 2012 |
Treatment of port wine stains with photodynamic therapy, using pulsed dye laser as a light source, compared with pulsed dye laser alone: a pilot study.
Topics: Adult; Aminolevulinic Acid; Female; Humans; Laser Coagulation; Photochemotherapy; Photosensitizing A | 2005 |
1 other study available for aminolevulinic acid and Port-Wine Stain
| Article | Year |
|---|---|
Photodynamic therapy with intradermal administration of 5-aminolevulinic acid for port-wine stains.
Topics: Aminolevulinic Acid; Animals; Chickens; Disease Models, Animal; Female; Injections, Intradermal; Inj | 2010 |