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aminolevulinic acid and Porphyria, Variegate

aminolevulinic acid has been researched along with Porphyria, Variegate in 2 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Porphyria, Variegate: An autosomal dominant porphyria that is due to a deficiency of protoporphyrinogen oxidase (EC 1.3.3.4) in the LIVER, the seventh enzyme in the 8-enzyme biosynthetic pathway of HEME. Clinical features include both neurological symptoms and cutaneous lesions. Patients excrete increased levels of porphyrin precursors, COPROPORPHYRINS and protoporphyrinogen.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Novakova, Z1
Milosevic, M1
Kutil, Z1
Ondrakova, M1
Havlinova, B1
Kasparek, P1
Sandoval-Acuña, C1
Korandova, Z1
Truksa, J1
Vrbacky, M1
Rohlena, J1
Barinka, C1
Di Pierro, E1
Ventura, P1
Brancaleoni, V1
Moriondo, V1
Marchini, S1
Tavazzi, D1
Nascimbeni, F1
Ferrari, MC1
Rocchi, E1
Cappellini, MD1

Other Studies

2 other studies available for aminolevulinic acid and Porphyria, Variegate

ArticleYear
Generation and characterization of human U-2 OS cell lines with the CRISPR/Cas9-edited protoporphyrinogen oxidase IX gene.
    Scientific reports, 2022, 10-12, Volume: 12, Issue:1

    Topics: Aminolevulinic Acid; Cell Line; CRISPR-Cas Systems; Heme; Humans; Oxidoreductases; Porphyria, Varieg

2022
Clinical, biochemical and genetic characteristics of Variegate Porphyria in Italy.
    Cellular and molecular biology (Noisy-le-Grand, France), 2009, Jul-01, Volume: 55, Issue:2

    Topics: Adult; Aged; Aminolevulinic Acid; Female; Flavoproteins; Genetic Association Studies; Genotype; Huma

2009