aminolevulinic acid has been researched along with Pituitary Neoplasms in 5 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
Pituitary Neoplasms: Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Incomplete resection of pituitary adenomas may result in recurrence." | 5.43 | Efficacy of 5-aminolevulinic acid based photodynamic therapy in pituitary adenomas-experimental study on rat and human cell cultures. ( Beseoglu, K; Cornelius, JF; Hänggi, D; Kamp, MA; Neumann, LM; Senger, B; Slotty, PJ; Steiger, HJ, 2016) |
| "In Group II human pituitary adenoma cell cultures were obtained from surgically resected adenoma tissue (n=15)." | 5.43 | Efficacy of 5-aminolevulinic acid based photodynamic therapy in pituitary adenomas-experimental study on rat and human cell cultures. ( Beseoglu, K; Cornelius, JF; Hänggi, D; Kamp, MA; Neumann, LM; Senger, B; Slotty, PJ; Steiger, HJ, 2016) |
| "Human pituitary adenoma cells could also be killed by 5-ALA PDT, however this required higher 5-ALA concentrations." | 5.43 | Efficacy of 5-aminolevulinic acid based photodynamic therapy in pituitary adenomas-experimental study on rat and human cell cultures. ( Beseoglu, K; Cornelius, JF; Hänggi, D; Kamp, MA; Neumann, LM; Senger, B; Slotty, PJ; Steiger, HJ, 2016) |
| "A total of 39 patients with pituitary adenomas were enrolled between June 2015 and January 2018 in 2, sequential, IRB-approved studies." | 1.48 | Intraoperative near-infrared imaging with receptor-specific versus passive delivery of fluorescent agents in pituitary adenomas. ( Buch, L; Cho, SS; Grady, MS; Jeon, J; Lee, JYK; Low, PS; Nag, S; Nasrallah, M; Singhal, S, 2018) |
| "Incomplete resection of pituitary adenomas may result in recurrence." | 1.43 | Efficacy of 5-aminolevulinic acid based photodynamic therapy in pituitary adenomas-experimental study on rat and human cell cultures. ( Beseoglu, K; Cornelius, JF; Hänggi, D; Kamp, MA; Neumann, LM; Senger, B; Slotty, PJ; Steiger, HJ, 2016) |
| "In Group II human pituitary adenoma cell cultures were obtained from surgically resected adenoma tissue (n=15)." | 1.43 | Efficacy of 5-aminolevulinic acid based photodynamic therapy in pituitary adenomas-experimental study on rat and human cell cultures. ( Beseoglu, K; Cornelius, JF; Hänggi, D; Kamp, MA; Neumann, LM; Senger, B; Slotty, PJ; Steiger, HJ, 2016) |
| "Human pituitary adenoma cells could also be killed by 5-ALA PDT, however this required higher 5-ALA concentrations." | 1.43 | Efficacy of 5-aminolevulinic acid based photodynamic therapy in pituitary adenomas-experimental study on rat and human cell cultures. ( Beseoglu, K; Cornelius, JF; Hänggi, D; Kamp, MA; Neumann, LM; Senger, B; Slotty, PJ; Steiger, HJ, 2016) |
| "But, the role of PDT for unresectable pituitary adenomas deserves further investigations." | 1.43 | 5-ALA Fluorescence in Native Pituitary Adenoma Cell Lines: Resection Control and Basis for Photodynamic Therapy (PDT)? ( Ewelt, C; Fortmann, T; Greve, B; Nemes, A; Poeschke, S; Prevedello, D; Santacroce, A; Senner, V; Stummer, W, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, SW | 1 |
| Donoho, DA | 1 |
| Zada, G | 1 |
| Cho, SS | 1 |
| Jeon, J | 1 |
| Buch, L | 1 |
| Nag, S | 1 |
| Nasrallah, M | 1 |
| Low, PS | 1 |
| Grady, MS | 1 |
| Singhal, S | 1 |
| Lee, JYK | 1 |
| Neumann, LM | 1 |
| Beseoglu, K | 1 |
| Slotty, PJ | 1 |
| Senger, B | 1 |
| Kamp, MA | 1 |
| Hänggi, D | 1 |
| Steiger, HJ | 1 |
| Cornelius, JF | 1 |
| Nemes, A | 1 |
| Fortmann, T | 1 |
| Poeschke, S | 1 |
| Greve, B | 1 |
| Prevedello, D | 1 |
| Santacroce, A | 1 |
| Stummer, W | 1 |
| Senner, V | 1 |
| Ewelt, C | 1 |
| Eljamel, MS | 1 |
| Leese, G | 1 |
| Moseley, H | 1 |
1 review available for aminolevulinic acid and Pituitary Neoplasms
| Article | Year |
|---|---|
Use of optical fluorescence agents during surgery for pituitary adenomas: current state of the field.
Topics: Adenoma; Aminolevulinic Acid; Fluorescent Dyes; Humans; Optical Imaging; Pituitary Neoplasms; Surger | 2019 |
1 trial available for aminolevulinic acid and Pituitary Neoplasms
| Article | Year |
|---|---|
Intraoperative optical identification of pituitary adenomas.
Topics: Adenoma; Aminolevulinic Acid; Diagnostic Imaging; False Negative Reactions; False Positive Reactions | 2009 |
3 other studies available for aminolevulinic acid and Pituitary Neoplasms
| Article | Year |
|---|---|
Intraoperative near-infrared imaging with receptor-specific versus passive delivery of fluorescent agents in pituitary adenomas.
Topics: Adenoma; Adult; Aged; Aminolevulinic Acid; Drug Delivery Systems; Female; Fluorescent Dyes; Folate R | 2018 |
Efficacy of 5-aminolevulinic acid based photodynamic therapy in pituitary adenomas-experimental study on rat and human cell cultures.
Topics: Adenoma; Aminolevulinic Acid; Animals; Biological Assay; Cell Line, Tumor; Cell Survival; Colorimetr | 2016 |
5-ALA Fluorescence in Native Pituitary Adenoma Cell Lines: Resection Control and Basis for Photodynamic Therapy (PDT)?
Topics: Adenoma; Aminolevulinic Acid; Cell Line, Tumor; Flow Cytometry; Fluorescence; Humans; Photochemother | 2016 |