aminolevulinic acid has been researched along with Peritoneal Carcinomatosis in 32 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
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"We conducted a phase I clinical trial to evaluate the sensitivity, specificity, and safety of cytoreductive surgery (CRS) under aminolevulinic acid-mediated photodynamic diagnosis (ALA-PDD) plus hyperthermic intraperitoneal chemotherapy (HIPEC) on 20 patients with peritoneal carcinomatosis (PC) from ovarian cancer and primary peritoneal carcinoma (PPC)." | 9.19 | Cytoreductive surgery under aminolevulinic acid-mediated photodynamic diagnosis plus hyperthermic intraperitoneal chemotherapy in patients with peritoneal carcinomatosis from ovarian cancer and primary peritoneal carcinoma: results of a phase I trial. ( Canbay, E; Endo, Y; Fujita, T; Ishibashi, H; Li, Y; Liu, Y; Nishioka, T; Ogura, S; Yonemura, Y, 2014) |
"5-aminolevulinic acid (5-ALA) is an intermediate substrate of heme metabolism." | 5.40 | Fluorescent detection of peritoneal metastasis in human colorectal cancer using 5-aminolevulinic acid. ( Fujiwara, H; Ichikawa, D; Ikoma, H; Inoue, K; Komatsu, S; Kondo, Y; Konishi, H; Kubota, T; Kuriu, Y; Morimura, R; Murayama, Y; Nakajima, M; Nakanishi, M; Okamoto, K; Otsuji, E; Sakakura, C; Shiozaki, A; Takahashi, K, 2014) |
"Twelve colorectal cancer patients suspected to have serosal invasion according to preoperative computed tomography (CT) were enrolled in this study." | 5.40 | Fluorescent detection of peritoneal metastasis in human colorectal cancer using 5-aminolevulinic acid. ( Fujiwara, H; Ichikawa, D; Ikoma, H; Inoue, K; Komatsu, S; Kondo, Y; Konishi, H; Kubota, T; Kuriu, Y; Morimura, R; Murayama, Y; Nakajima, M; Nakanishi, M; Okamoto, K; Otsuji, E; Sakakura, C; Shiozaki, A; Takahashi, K, 2014) |
"We conducted a phase I clinical trial to evaluate the sensitivity, specificity, and safety of cytoreductive surgery (CRS) under aminolevulinic acid-mediated photodynamic diagnosis (ALA-PDD) plus hyperthermic intraperitoneal chemotherapy (HIPEC) on 20 patients with peritoneal carcinomatosis (PC) from ovarian cancer and primary peritoneal carcinoma (PPC)." | 5.19 | Cytoreductive surgery under aminolevulinic acid-mediated photodynamic diagnosis plus hyperthermic intraperitoneal chemotherapy in patients with peritoneal carcinomatosis from ovarian cancer and primary peritoneal carcinoma: results of a phase I trial. ( Canbay, E; Endo, Y; Fujita, T; Ishibashi, H; Li, Y; Liu, Y; Nishioka, T; Ogura, S; Yonemura, Y, 2014) |
"Nude rats were used to create a model of peritoneal carcinomatosis resulting from ovarian cancer and the effectiveness of PDT with 5-aminolevulinic acid methyl ester hydrochloride (methyl-ALA-PDT) was determined." | 3.83 | A Strategy Using Photodynamic Therapy and Clofibric Acid to Treat Peritoneal Dissemination of Ovarian Cancer. ( Futagami, M; Kobayashi, A; Miura, R; Mizunuma, H; Mizunuma, M; Shigeto, T; Yamauchi, A; Yokoyama, Y, 2016) |
"The current study examined the effectiveness of concurrent therapy using photodynamic therapy (PDT) and clofibric acid (CA) to treat peritoneal carcinomatosis resulting from ovarian cancer." | 3.83 | A Strategy Using Photodynamic Therapy and Clofibric Acid to Treat Peritoneal Dissemination of Ovarian Cancer. ( Futagami, M; Kobayashi, A; Miura, R; Mizunuma, H; Mizunuma, M; Shigeto, T; Yamauchi, A; Yokoyama, Y, 2016) |
"5-Aminolevulinic acid was orally administered 3-14 hours before surgery using a dosage of 1 mg/kg, 4-9 hours using 10 mg/kg, and 9-16 hours using 10 mg/kg, respectively." | 2.84 | Photodynamic diagnosis with 5-aminolevulinic acid for intraoperative detection of peritoneal metastases of ovarian cancer: A feasibility and dose finding study. ( Hillemanns, P; Klapdor, R; Reif, J; Stepp, H; Wimberger, P, 2017) |
"With a prospective feasibility study, we aimed to analyse the effect of different time points for application and dosage of preoperative oral 5-aminolevulinic acid administration for photodynamic diagnosis of peritoneal metastases in ovarian cancer patients." | 2.84 | Photodynamic diagnosis with 5-aminolevulinic acid for intraoperative detection of peritoneal metastases of ovarian cancer: A feasibility and dose finding study. ( Hillemanns, P; Klapdor, R; Reif, J; Stepp, H; Wimberger, P, 2017) |
" 5-Aminolevulinic acid was orally administered 3-14 hours before surgery using a dosage of 1 mg/kg, 4-9 hours using 10 mg/kg, and 9-16 hours using 10 mg/kg, respectively." | 2.84 | Photodynamic diagnosis with 5-aminolevulinic acid for intraoperative detection of peritoneal metastases of ovarian cancer: A feasibility and dose finding study. ( Hillemanns, P; Klapdor, R; Reif, J; Stepp, H; Wimberger, P, 2017) |
" Orally applied 5-aminolevulinic acid with a dosage of 1 mg/kg revealed no detectable fluorescence." | 2.84 | Photodynamic diagnosis with 5-aminolevulinic acid for intraoperative detection of peritoneal metastases of ovarian cancer: A feasibility and dose finding study. ( Hillemanns, P; Klapdor, R; Reif, J; Stepp, H; Wimberger, P, 2017) |
" 5-Aminolevulinic acid should be used at a dosage of at least 10 mg/kg 4-9 hours preoperatively." | 2.84 | Photodynamic diagnosis with 5-aminolevulinic acid for intraoperative detection of peritoneal metastases of ovarian cancer: A feasibility and dose finding study. ( Hillemanns, P; Klapdor, R; Reif, J; Stepp, H; Wimberger, P, 2017) |
"In total, 26 patients suspected for ovarian cancer underwent intraoperative photodynamic diagnosis with 5-aminolevulinic acid." | 2.84 | Photodynamic diagnosis with 5-aminolevulinic acid for intraoperative detection of peritoneal metastases of ovarian cancer: A feasibility and dose finding study. ( Hillemanns, P; Klapdor, R; Reif, J; Stepp, H; Wimberger, P, 2017) |
"5-aminolevulinic acid (ALA) is a naturally occurring amino acid that is a protoporphyrin IX (PpIX) precursor and a next-generation photosensitive substance." | 2.52 | Clinical applications of 5-aminolevulinic acid-mediated fluorescence for gastric cancer. ( Hanazaki, K; Inoue, K; Namikawa, T; Shuin, T; Yatabe, T, 2015) |
"Ovarian cancer is among the deadliest in women." | 2.48 | Photodiagnosis and photodynamic therapy of peritoneal metastasis of ovarian cancer. ( Ascencio, M; Collinet, P; Guyon, L; Mordon, S, 2012) |
"As a peritoneal surface malignancy, primary peritoneal papillary serous carcinoma (PPPSC) almost always occurs in women." | 1.40 | Photodynamic detection and management of intraperitoneal spreading of primary peritoneal papillary serous carcinoma in a man: report of a case. ( Canbay, E; Endo, Y; Hirano, M; Ishibashi, H; Kitai, T; Mizumoto, A; Nishino, E; Ogura, S; Sako, S; Yonemura, Y, 2014) |
"5-aminolevulinic acid (5-ALA) is an intermediate substrate of heme metabolism." | 1.40 | Fluorescent detection of peritoneal metastasis in human colorectal cancer using 5-aminolevulinic acid. ( Fujiwara, H; Ichikawa, D; Ikoma, H; Inoue, K; Komatsu, S; Kondo, Y; Konishi, H; Kubota, T; Kuriu, Y; Morimura, R; Murayama, Y; Nakajima, M; Nakanishi, M; Okamoto, K; Otsuji, E; Sakakura, C; Shiozaki, A; Takahashi, K, 2014) |
"Twelve colorectal cancer patients suspected to have serosal invasion according to preoperative computed tomography (CT) were enrolled in this study." | 1.40 | Fluorescent detection of peritoneal metastasis in human colorectal cancer using 5-aminolevulinic acid. ( Fujiwara, H; Ichikawa, D; Ikoma, H; Inoue, K; Komatsu, S; Kondo, Y; Konishi, H; Kubota, T; Kuriu, Y; Morimura, R; Murayama, Y; Nakajima, M; Nakanishi, M; Okamoto, K; Otsuji, E; Sakakura, C; Shiozaki, A; Takahashi, K, 2014) |
"A 35-year-old female with scirrhous stomach cancer (stage IV) was treated with a combination of 5-aminolevulinic acid (ALA), sodium dichloroacetate (DCA), hyperthermotherapy, and immunotherapy as terminal care." | 1.39 | A patient with scirrhous stomach cancer treated with combination of hyperthermotherapy and 5-aminolevulinic acid (ALA). ( Goto, S; Kamigaki, T; Saito, M; Yano, K, 2013) |
"Precise staging of gastric cancer is essential when selecting for the appropriate treatment approach." | 1.38 | Staging fluorescence laparoscopy for gastric cancer by using 5-aminolevulinic acid. ( Fujiwara, H; Harada, Y; Ichikawa, D; Ikoma, H; Koizumi, N; Kokuba, Y; Komatsu, S; Kubota, T; Kuriu, Y; Murayama, Y; Nakanishi, M; Ochiai, T; Okamoto, K; Otsuji, E; Shiozaki, A; Takamatsu, T, 2012) |
"Peritoneal carcinomatosis was induced by intraperitoneal 5×10(6)NuTu-19 cells injection in 60 female rats Fisher 344." | 1.36 | Continuous or fractionated photodynamic therapy? Comparison of three PDT schemes for ovarian peritoneal micrometastasis treatment in a rat model. ( Ascencio, M; Colin, P; Collinet, P; Estevez, JP; Farine, MO; Mordon, S, 2010) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (9.38) | 18.2507 |
2000's | 9 (28.13) | 29.6817 |
2010's | 18 (56.25) | 24.3611 |
2020's | 2 (6.25) | 2.80 |
Authors | Studies |
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Saito, T | 1 |
Ebihara, Y | 1 |
Li, L | 1 |
Shirosaki, T | 1 |
Iijima, H | 1 |
Tanaka, K | 1 |
Nakanishi, Y | 1 |
Asano, T | 1 |
Noji, T | 1 |
Kurashima, Y | 1 |
Murakami, S | 1 |
Nakamura, T | 1 |
Tsuchikawa, T | 1 |
Okamura, K | 1 |
Shichinohe, T | 1 |
Hirano, S | 1 |
Luan, S | 1 |
Tran, NT | 1 |
Xue, HY | 1 |
Wong, HL | 1 |
Canbay, E | 3 |
Ishibashi, H | 3 |
Sako, S | 2 |
Kitai, T | 1 |
Nishino, E | 2 |
Hirano, M | 1 |
Mizumoto, A | 1 |
Endo, Y | 2 |
Ogura, S | 3 |
Yonemura, Y | 3 |
Saito, M | 1 |
Yano, K | 1 |
Kamigaki, T | 1 |
Goto, S | 1 |
Guyon, L | 3 |
Farine, MO | 2 |
Lesage, JC | 2 |
Gevaert, AM | 1 |
Simonin, S | 1 |
Schmitt, C | 1 |
Collinet, P | 3 |
Mordon, S | 4 |
Kondo, Y | 1 |
Murayama, Y | 2 |
Konishi, H | 1 |
Morimura, R | 1 |
Komatsu, S | 2 |
Shiozaki, A | 2 |
Kuriu, Y | 2 |
Ikoma, H | 2 |
Kubota, T | 2 |
Nakanishi, M | 2 |
Ichikawa, D | 2 |
Fujiwara, H | 2 |
Okamoto, K | 2 |
Sakakura, C | 1 |
Takahashi, K | 1 |
Inoue, K | 2 |
Nakajima, M | 1 |
Otsuji, E | 3 |
Liu, Y | 1 |
Fujita, T | 1 |
Nishioka, T | 1 |
Li, Y | 1 |
Kishi, K | 4 |
Fujiwara, Y | 4 |
Yano, M | 4 |
Motoori, M | 3 |
Sugimura, K | 3 |
Ohue, M | 4 |
Noura, S | 2 |
Marubashi, S | 1 |
Takahashi, H | 4 |
Sakon, M | 3 |
Namikawa, T | 1 |
Yatabe, T | 1 |
Shuin, T | 1 |
Hanazaki, K | 1 |
Koizumi, N | 2 |
Harada, Y | 2 |
Minamikawa, T | 1 |
Tanaka, H | 1 |
Takamatsu, T | 2 |
Yokoyama, Y | 1 |
Shigeto, T | 1 |
Miura, R | 1 |
Kobayashi, A | 1 |
Mizunuma, M | 1 |
Yamauchi, A | 1 |
Futagami, M | 1 |
Mizunuma, H | 1 |
Endou, Y | 1 |
Ushimaru, Y | 1 |
Omori, T | 1 |
Moon, JH | 1 |
Yanagimoto, Y | 1 |
Yasui, M | 1 |
Kobayashi, S | 1 |
Akita, H | 1 |
Miyoshi, N | 1 |
Tomokuni, A | 1 |
Hillemanns, P | 1 |
Wimberger, P | 1 |
Reif, J | 1 |
Stepp, H | 1 |
Klapdor, R | 1 |
Estevez, JP | 1 |
Ascencio, M | 2 |
Colin, P | 1 |
Inoue, M | 1 |
Miyashiro, I | 1 |
Shingai, T | 1 |
Gotoh, K | 1 |
Yamada, T | 1 |
Ohigashi, H | 1 |
Ishikawa, O | 1 |
Betrouni, N | 1 |
Ochiai, T | 1 |
Kokuba, Y | 1 |
Lüdicke, F | 2 |
Gabrecht, T | 1 |
Lange, N | 1 |
Wagnières, G | 1 |
Van Den Bergh, H | 1 |
Berclaz, L | 1 |
Major, AL | 4 |
Löning, M | 1 |
Diddens, H | 1 |
Küpker, W | 1 |
Diedrich, K | 1 |
Hüttmann, G | 1 |
Zöpf, T | 1 |
Schneider, AR | 1 |
Weickert, U | 1 |
Riemann, JF | 1 |
Arnold, JC | 1 |
Till, H | 1 |
Bergmann, F | 1 |
Metzger, R | 1 |
Haeberle, B | 1 |
von Schweinitz, D | 1 |
Prosst, R | 1 |
Rose, GS | 1 |
Chapman, CF | 1 |
Hiserodt, JC | 1 |
Tromberg, BJ | 2 |
Krasieva, TB | 1 |
Tadir, Y | 2 |
Haller, U | 1 |
DiSaia, PJ | 1 |
Berns, MW | 2 |
Hornung, R | 1 |
McHale, M | 1 |
Liaw, LH | 1 |
Sabiniano, LA | 1 |
Gahlen, J | 3 |
Stern, J | 2 |
Laubach, HH | 1 |
Pietschmann, M | 3 |
Herfarth, C | 3 |
Orth, K | 1 |
Russ, D | 1 |
Steiner, R | 1 |
Beger, HG | 1 |
Prosst, RL | 2 |
Canis, M | 1 |
Botchorishvili, R | 1 |
Berreni, N | 1 |
Manhes, H | 1 |
Wattiez, A | 1 |
Mage, G | 1 |
Pouly, JL | 1 |
Bruhat, MA | 1 |
Haase, T | 1 |
Rheinwald, M | 1 |
Skopp, G | 1 |
Campana, A | 1 |
Campand, A | 1 |
3 reviews available for aminolevulinic acid and Peritoneal Carcinomatosis
Article | Year |
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Clinical applications of 5-aminolevulinic acid-mediated fluorescence for gastric cancer.
Topics: Aminolevulinic Acid; Fluorescent Dyes; Humans; Laparoscopy; Luminescent Measurements; Neoplasm Stagi | 2015 |
Recent advances in photodynamic diagnosis of gastric cancer using 5-aminolevulinic acid.
Topics: Aminolevulinic Acid; Animals; Biomarkers, Tumor; Humans; Intraoperative Care; Luminescent Measuremen | 2016 |
Photodiagnosis and photodynamic therapy of peritoneal metastasis of ovarian cancer.
Topics: Aminolevulinic Acid; Angiogenesis Inhibitors; Animals; Combined Modality Therapy; Female; Humans; Im | 2012 |
3 trials available for aminolevulinic acid and Peritoneal Carcinomatosis
26 other studies available for aminolevulinic acid and Peritoneal Carcinomatosis
Article | Year |
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A novel laparoscopic near-infrared fluorescence spectrum system for photodynamic diagnosis of peritoneal dissemination in pancreatic cancer.
Topics: Aminolevulinic Acid; Animals; Fluorescence; Humans; Laparoscopy; Mice; Pancreatic Neoplasms; Periton | 2021 |
Development of a high payload, cancer-targeting liposomes of methyl aminolevulinate for intraoperative photodynamic diagnosis/therapy of peritoneal carcinomatosis.
Topics: Aminolevulinic Acid; Humans; Liposomes; Peritoneal Neoplasms; Photochemotherapy; Photosensitizing Ag | 2021 |
Photodynamic detection and management of intraperitoneal spreading of primary peritoneal papillary serous carcinoma in a man: report of a case.
Topics: Administration, Oral; Aminolevulinic Acid; Combined Modality Therapy; Cystadenocarcinoma, Papillary; | 2014 |
A patient with scirrhous stomach cancer treated with combination of hyperthermotherapy and 5-aminolevulinic acid (ALA).
Topics: Adenocarcinoma, Scirrhous; Adult; Aminolevulinic Acid; Antineoplastic Combined Chemotherapy Protocol | 2013 |
Photodynamic therapy of ovarian cancer peritoneal metastasis with hexaminolevulinate: a toxicity study.
Topics: Aminolevulinic Acid; Animals; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Dose-Respons | 2014 |
Fluorescent detection of peritoneal metastasis in human colorectal cancer using 5-aminolevulinic acid.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Animals; Colorectal Neoplasms; HT29 Cells; Huma | 2014 |
Diagnostic laparoscopy with 5-aminolevulinic-acid-mediated photodynamic diagnosis enhances the detection of peritoneal micrometastases in advanced gastric cancer.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Laparoscopy; Male; Middle Aged; | 2014 |
A Strategy Using Photodynamic Therapy and Clofibric Acid to Treat Peritoneal Dissemination of Ovarian Cancer.
Topics: Aminolevulinic Acid; Animals; Clofibric Acid; Female; Hypolipidemic Agents; Light; Mice; Mice, Inbre | 2016 |
Usefulness of diagnostic laparoscopy with 5-aminolevulinic acid (ALA)-mediated photodynamic diagnosis for the detection of peritoneal micrometastasis in advanced gastric cancer after chemotherapy.
Topics: Adult; Aged; Aminolevulinic Acid; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cisp | 2016 |
5-Aminolevulinic Acid Fluorescence in Detection of Peritoneal Metastases.
Topics: Aminolevulinic Acid; Cytoreduction Surgical Procedures; Female; Fluorescence; Follow-Up Studies; Hum | 2016 |
Prognostic Significance of Basing Treatment Strategy on the Results of Photodynamic Diagnosis in Advanced Gastric Cancer.
Topics: Aged; Aminolevulinic Acid; Antineoplastic Combined Chemotherapy Protocols; Ascites; Female; Gastrect | 2017 |
Continuous or fractionated photodynamic therapy? Comparison of three PDT schemes for ovarian peritoneal micrometastasis treatment in a rat model.
Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Disease Models, Animal; Female; Ovarian Neoplasms; Per | 2010 |
Staging laparoscopy using ALA-mediated photodynamic diagnosis improves the detection of peritoneal metastases in advanced gastric cancer.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Animals; Disease Models, Animal; Female; Fluorescence; | 2012 |
Development of a new illumination procedure for photodynamic therapy of the abdominal cavity.
Topics: Abdominal Cavity; Adenocarcinoma; Aminolevulinic Acid; Animals; Cell Line, Tumor; Female; Intestines | 2012 |
Staging fluorescence laparoscopy for gastric cancer by using 5-aminolevulinic acid.
Topics: Administration, Oral; Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Fluorescence; Humans; La | 2012 |
Photodynamic diagnosis of ovarian cancer using hexaminolaevulinate: a preclinical study.
Topics: Aminolevulinic Acid; Animals; Diagnostic Techniques and Procedures; Disease Models, Animal; Drug Eva | 2003 |
Improved preoperative tumor staging by 5-aminolevulinic acid induced fluorescence laparoscopy.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Digestive System Neoplasm | 2005 |
Laparoscopic fluorescence diagnosis of peritoneal metastases from human hepatoblastoma in nude rats.
Topics: Aminolevulinic Acid; Animals; Cell Line, Tumor; Disease Models, Animal; Fluorescence; Fluorescent Dy | 2006 |
In vivo fluorescence detection of ovarian cancer in the NuTu-19 epithelial ovarian cancer animal model using 5-aminolevulinic acid (ALA).
Topics: Aminolevulinic Acid; Animals; Disease Models, Animal; Epithelium; Feasibility Studies; Female; Fluor | 1997 |
In vivo detection of metastatic ovarian cancer by means of 5-aminolevulinic acid-induced fluorescence in a rat model.
Topics: Aminolevulinic Acid; Animals; Disease Models, Animal; Female; Fluorescence; Injections, Intravenous; | 1998 |
Improving diagnostic staging laparoscopy using intraperitoneal lavage of delta-aminolevulinic acid (ALA) for laparoscopic fluorescence diagnosis.
Topics: Aminolevulinic Acid; Animals; Colonic Neoplasms; Fluorescence; Gastrointestinal Neoplasms; Humans; L | 1999 |
Fluorescence detection of small gastrointestinal tumours: principles, technique, first clinical experience.
Topics: Aminolevulinic Acid; Endoscopy; Fluorescence; Gastrointestinal Neoplasms; Humans; Laparoscopy; Perit | 2000 |
Systemic vs local administration of delta-aminolevulinic acid for laparoscopic fluorescence diagnosis of malignant intra-abdominal tumors. Experimental study.
Topics: Aminolevulinic Acid; Animals; Disease Models, Animal; Fluorescence Polarization; Injections, Intrape | 2001 |
5-aminolevulinic acid-induced (ALA) fluorescence for the laparoscopic diagnosis of peritoneal metastasis. AST An experimental study.
Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Female; Fluorescence; Laparoscopy; Ovarian Neoplasms; | 2001 |
Laparoscopic fluorescence diagnosis for intraabdominal fluorescence targeting of peritoneal carcinosis experimental studies.
Topics: Aminolevulinic Acid; Animals; Colonic Neoplasms; Fluorescence; Laparoscopy; Neoplasm Staging; Perito | 2002 |
Feasibility study to detect ovarian cancer micrometastases by fluorescence photodetection.
Topics: Adenocarcinoma; Aminolevulinic Acid; Fear; Female; Fluorescence; Humans; Laparoscopy; Middle Aged; O | 2002 |