aminolevulinic acid has been researched along with Osteogenic Sarcoma in 8 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to test the efficacy of aminolevulinic acid-mediated photodynamic therapy (PDT) against the human osteosarcoma cell line MG-63." | 7.83 | Aminolevulinic Acid-Mediated Photodynamic Therapy Causes Cell Death in MG-63 Human Osteosarcoma Cells. ( Baugher, PJ; Rossi, V; White, B, 2016) |
| "We investigated the killing effect of low-intensity ultrasound combined with 5-aminolevulinic acid (5-ALA) on the rat osteosarcoma cell line UMR-106." | 7.81 | Mechanism of rat osteosarcoma cell apoptosis induced by a combination of low-intensity ultrasound and 5-aminolevulinic acid in vitro. ( Cao, WW; Hu, Z; Li, QS; Li, YN; Wang, JH; Yang, B; Zhou, Q, 2015) |
| "We observed that two osteosarcoma cell lines from the same tumor displayed marked differences in their sensitivities to photodynamic therapy (PDT) with aminolevulinic acid hexyl ester (hALA-PDT)." | 7.75 | Synergistic increase in osteosarcoma cell sensitivity to photodynamic therapy with aminolevulinic acid hexyl ester in the presence of hyperthermia. ( Matsumura, Y; Nomura, J; Tagawa, T; Watanabe, Y; Yanase, S, 2009) |
| "Flow cytometry was used to evaluate the intracellular accumulation of protoporphyrin IX (PpIX), a metabolic product of aminolevulinic acid, in two human mandibular osteosarcoma cell lines (HOSM-1 and HOSM-2) treated with HT, hALA-PDT, or hALA-PDT combined with HT (PDT + HT)." | 7.75 | Synergistic increase in osteosarcoma cell sensitivity to photodynamic therapy with aminolevulinic acid hexyl ester in the presence of hyperthermia. ( Matsumura, Y; Nomura, J; Tagawa, T; Watanabe, Y; Yanase, S, 2009) |
| "In this study, the effectiveness and mechanism of combination therapy of 5-aminolevulinic acid-based photodynamic therapy (ALA-PDT) with simultaneous hyperthermia (HT) on human-derived osteosarcoma in vivo were examined." | 7.73 | Synergistic interaction of 5-aminolevulinic acid-based photodynamic therapy with simultaneous hyperthermia in an osteosarcoma tumor model. ( Fujii, T; Matsumura, Y; Nagata, T; Nomura, J; Tagawa, T; Yanase, S, 2006) |
| "Osteosarcoma is the most common type of primary malignant bone tumor diagnosed in the United States among adolescents and children." | 5.43 | Aminolevulinic Acid-Mediated Photodynamic Therapy Causes Cell Death in MG-63 Human Osteosarcoma Cells. ( Baugher, PJ; Rossi, V; White, B, 2016) |
| "The aim of this study was to test the efficacy of aminolevulinic acid-mediated photodynamic therapy (PDT) against the human osteosarcoma cell line MG-63." | 3.83 | Aminolevulinic Acid-Mediated Photodynamic Therapy Causes Cell Death in MG-63 Human Osteosarcoma Cells. ( Baugher, PJ; Rossi, V; White, B, 2016) |
| "We investigated the killing effect of low-intensity ultrasound combined with 5-aminolevulinic acid (5-ALA) on the rat osteosarcoma cell line UMR-106." | 3.81 | Mechanism of rat osteosarcoma cell apoptosis induced by a combination of low-intensity ultrasound and 5-aminolevulinic acid in vitro. ( Cao, WW; Hu, Z; Li, QS; Li, YN; Wang, JH; Yang, B; Zhou, Q, 2015) |
| "We observed that two osteosarcoma cell lines from the same tumor displayed marked differences in their sensitivities to photodynamic therapy (PDT) with aminolevulinic acid hexyl ester (hALA-PDT)." | 3.75 | Synergistic increase in osteosarcoma cell sensitivity to photodynamic therapy with aminolevulinic acid hexyl ester in the presence of hyperthermia. ( Matsumura, Y; Nomura, J; Tagawa, T; Watanabe, Y; Yanase, S, 2009) |
| "Flow cytometry was used to evaluate the intracellular accumulation of protoporphyrin IX (PpIX), a metabolic product of aminolevulinic acid, in two human mandibular osteosarcoma cell lines (HOSM-1 and HOSM-2) treated with HT, hALA-PDT, or hALA-PDT combined with HT (PDT + HT)." | 3.75 | Synergistic increase in osteosarcoma cell sensitivity to photodynamic therapy with aminolevulinic acid hexyl ester in the presence of hyperthermia. ( Matsumura, Y; Nomura, J; Tagawa, T; Watanabe, Y; Yanase, S, 2009) |
| "In the present study, we have investigated a combination of photodynamic therapy (PDT) using 5-aminolevulinic acid (ALA) and simultaneous hyperthermia (HT) on osteosarcoma (HOSM-1) cells, squamous cell carcinoma (KB) cells and fibroblasts (HF), including an assessment of the differences in the sensitivity of these cells to such treatment in vitro." | 3.73 | Enhancement of the effect of 5-aminolevulinic acid-based photodynamic therapy by simultaneous hyperthermia. ( Kinoshita, M; Matsumura, Y; Nagai, K; Nakanishi, H; Nomura, J; Ohnishi, Y; Tagawa, T; Tokuda, T; Yanase, S, 2005) |
| "In this study, the effectiveness and mechanism of combination therapy of 5-aminolevulinic acid-based photodynamic therapy (ALA-PDT) with simultaneous hyperthermia (HT) on human-derived osteosarcoma in vivo were examined." | 3.73 | Synergistic interaction of 5-aminolevulinic acid-based photodynamic therapy with simultaneous hyperthermia in an osteosarcoma tumor model. ( Fujii, T; Matsumura, Y; Nagata, T; Nomura, J; Tagawa, T; Yanase, S, 2006) |
| "Osteosarcoma is insensitive to radiation." | 1.62 | Using a Hybrid Radioenhancer to Discover Tumor Cell-targeted Treatment for Osteosarcoma: An In Vitro Study. ( Chen, LC; Chen, MH; Liu, TY; Shueng, PW; Tung, FI; Wang, YC, 2021) |
| "Osteosarcoma is the most common type of primary malignant bone tumor diagnosed in the United States among adolescents and children." | 1.43 | Aminolevulinic Acid-Mediated Photodynamic Therapy Causes Cell Death in MG-63 Human Osteosarcoma Cells. ( Baugher, PJ; Rossi, V; White, B, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Tung, FI | 1 |
| Chen, LC | 1 |
| Wang, YC | 1 |
| Chen, MH | 1 |
| Shueng, PW | 1 |
| Liu, TY | 1 |
| Li, Y | 1 |
| Zhou, Q | 2 |
| Hu, Z | 2 |
| Yang, B | 2 |
| Li, Q | 1 |
| Wang, J | 1 |
| Zheng, J | 1 |
| Cao, W | 1 |
| Li, YN | 1 |
| Wang, JH | 1 |
| Li, QS | 1 |
| Cao, WW | 1 |
| White, B | 1 |
| Rossi, V | 1 |
| Baugher, PJ | 1 |
| Yanase, S | 3 |
| Nomura, J | 3 |
| Matsumura, Y | 3 |
| Watanabe, Y | 1 |
| Tagawa, T | 3 |
| Coupienne, I | 1 |
| Fettweis, G | 1 |
| Piette, J | 1 |
| Nagai, K | 1 |
| Kinoshita, M | 1 |
| Nakanishi, H | 1 |
| Ohnishi, Y | 1 |
| Tokuda, T | 1 |
| Nagata, T | 1 |
| Fujii, T | 1 |
8 other studies available for aminolevulinic acid and Osteogenic Sarcoma
| Article | Year |
|---|---|
Using a Hybrid Radioenhancer to Discover Tumor Cell-targeted Treatment for Osteosarcoma: An In Vitro Study.
Topics: Aminolevulinic Acid; Apoptosis; Cell Line, Tumor; Cell Survival; Humans; Osteosarcoma; Reactive Oxyg | 2021 |
5-Aminolevulinic Acid-Based Sonodynamic Therapy Induces the Apoptosis of Osteosarcoma in Mice.
Topics: Aminolevulinic Acid; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Immunohistochemistry; | 2015 |
Mechanism of rat osteosarcoma cell apoptosis induced by a combination of low-intensity ultrasound and 5-aminolevulinic acid in vitro.
Topics: Aminolevulinic Acid; Apoptosis; Cell Line, Tumor; Flow Cytometry; Humans; Osteosarcoma; Reactive Oxy | 2015 |
Aminolevulinic Acid-Mediated Photodynamic Therapy Causes Cell Death in MG-63 Human Osteosarcoma Cells.
Topics: Aminolevulinic Acid; Bone Neoplasms; Cell Death; Cell Line, Tumor; Cell Survival; Humans; Osteosarco | 2016 |
Synergistic increase in osteosarcoma cell sensitivity to photodynamic therapy with aminolevulinic acid hexyl ester in the presence of hyperthermia.
Topics: Aminolevulinic Acid; Cell Line, Tumor; Combined Modality Therapy; Humans; Hyperthermia, Induced; Inf | 2009 |
RIP3 expression induces a death profile change in U2OS osteosarcoma cells after 5-ALA-PDT.
Topics: Aminolevulinic Acid; Apoptosis; Autophagy; Blotting, Western; Bone Neoplasms; Cell Line, Tumor; Cell | 2011 |
Enhancement of the effect of 5-aminolevulinic acid-based photodynamic therapy by simultaneous hyperthermia.
Topics: Aminolevulinic Acid; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Cell Separation; Ch | 2005 |
Synergistic interaction of 5-aminolevulinic acid-based photodynamic therapy with simultaneous hyperthermia in an osteosarcoma tumor model.
Topics: Aminolevulinic Acid; Animals; Antigens, Neoplasm; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell L | 2006 |