Page last updated: 2024-10-16

aminolevulinic acid and Neoplasms, Skull Base

aminolevulinic acid has been researched along with Neoplasms, Skull Base in 9 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Research Excerpts

ExcerptRelevanceReference
"The first case was a small olfactory groove meningioma resected via a trans-eyebrow, subfrontal approach."5.51Surgery of Small Anterior Skull Base Meningiomas by Endoscopic 5-Aminolevulinic Acid Fluorescence Guidance: First Clinical Experience. ( Beez, T; Cornelius, JF; Kamp, MA; Knipps, J; Krause-Molle, Z; Petridis, AK; Sabel, M; Schipper, J; Steiger, HJ; Tortora, A, 2019)
"The patient harboring a sphenoid wing meningioma with intraorbital extension underwent radical resection of the tumor with both visibly and nonvisibly fluorescent regions."5.37Quantitative and qualitative 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in skull base meningiomas. ( Bekelis, K; Erkmen, K; Harris, BT; Kim, A; Leblond, F; Paulsen, KD; Roberts, DW; Valdés, PA; Wilson, BC, 2011)
"The first case was a small olfactory groove meningioma resected via a trans-eyebrow, subfrontal approach."1.51Surgery of Small Anterior Skull Base Meningiomas by Endoscopic 5-Aminolevulinic Acid Fluorescence Guidance: First Clinical Experience. ( Beez, T; Cornelius, JF; Kamp, MA; Knipps, J; Krause-Molle, Z; Petridis, AK; Sabel, M; Schipper, J; Steiger, HJ; Tortora, A, 2019)
"The patient harboring a sphenoid wing meningioma with intraorbital extension underwent radical resection of the tumor with both visibly and nonvisibly fluorescent regions."1.37Quantitative and qualitative 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in skull base meningiomas. ( Bekelis, K; Erkmen, K; Harris, BT; Kim, A; Leblond, F; Paulsen, KD; Roberts, DW; Valdés, PA; Wilson, BC, 2011)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (88.89)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Turcotte, EL1
Rahme, RJ1
Merrill, SA1
Hess, RA1
Lettieri, SC1
Bendok, BR1
Cornelius, JF2
Kamp, MA1
Tortora, A1
Knipps, J1
Krause-Molle, Z1
Beez, T1
Petridis, AK1
Sabel, M1
Schipper, J1
Steiger, HJ1
Rustemi, O3
Della Puppa, A4
Scienza, R2
Bekelis, K2
Roberts, DW2
Gioffrè, G2
Troncon, I1
Lombardi, G1
Rolma, G1
Sergi, M1
Munari, M1
Cecchin, D1
Gardiman, MP1
Slotty, PJ1
Valdés, PA1
Erkmen, K1
Leblond, F1
Kim, A1
Wilson, BC1
Harris, BT1
Paulsen, KD1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Computer Based Algorithm for Patient Specific Implants for Cranioplasty in Patients With Skull Defects: a Prospective Clinical Trial[NCT02828306]15 participants (Actual)Observational2016-09-30Completed
5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas[NCT05850377]90 participants (Anticipated)Observational2023-06-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

9 other studies available for aminolevulinic acid and Neoplasms, Skull Base

ArticleYear
The Utility of 5-Aminolevulinic Acid for Microsurgical Resection of Meningiomas.
    World neurosurgery, 2020, Volume: 139

    Topics: Aged; Aminolevulinic Acid; Female; Humans; Male; Meningeal Neoplasms; Meningioma; Microsurgery; Midd

2020
Surgery of Small Anterior Skull Base Meningiomas by Endoscopic 5-Aminolevulinic Acid Fluorescence Guidance: First Clinical Experience.
    World neurosurgery, 2019, Volume: 122

    Topics: Adult; Aged; Aminolevulinic Acid; Female; Humans; Male; Meningeal Neoplasms; Meningioma; Microsurger

2019
Hyperostosis and osteolysis in skull base meningiomas: are different nuances of 5-ALA fluorescence related to different invasion patterns?
    Journal of neurosurgical sciences, 2019, Volume: 63, Issue:4

    Topics: Aminolevulinic Acid; Fluorescence; Humans; Hyperostosis; Meningeal Neoplasms; Meningioma; Osteolysis

2019
5-Aminolevulinic acid-guided resection of bone-invasive meningiomas.
    Neurosurgical focus, 2013, Volume: 35, Issue:4

    Topics: Aminolevulinic Acid; Female; Humans; Meningeal Neoplasms; Photosensitizing Agents; Protoporphyrins;

2013
Response.
    Neurosurgical focus, 2013, Volume: 35, Issue:4

    Topics: Aminolevulinic Acid; Female; Humans; Meningeal Neoplasms; Photosensitizing Agents; Protoporphyrins;

2013
Predictive value of intraoperative 5-aminolevulinic acid-induced fluorescence for detecting bone invasion in meningioma surgery.
    Journal of neurosurgery, 2014, Volume: 120, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Male; Meningeal Neoplasms; Meni

2014
Predictive value of intraoperative 5-aminolevulinic acid-induced fluorescence for detecting bone invasion in meningioma surgery.
    Journal of neurosurgery, 2014, Volume: 120, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Male; Meningeal Neoplasms; Meni

2014
Predictive value of intraoperative 5-aminolevulinic acid-induced fluorescence for detecting bone invasion in meningioma surgery.
    Journal of neurosurgery, 2014, Volume: 120, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Male; Meningeal Neoplasms; Meni

2014
Predictive value of intraoperative 5-aminolevulinic acid-induced fluorescence for detecting bone invasion in meningioma surgery.
    Journal of neurosurgery, 2014, Volume: 120, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Male; Meningeal Neoplasms; Meni

2014
Meningioma surgery in the era of 5-aminolevulinic acid fluorescence-guided surgery.
    Journal of neurosurgery, 2014, Volume: 121, Issue:3

    Topics: Aminolevulinic Acid; Female; Humans; Male; Meningeal Neoplasms; Meningioma; Skull Base Neoplasms

2014
Response.
    Journal of neurosurgery, 2014, Volume: 121, Issue:3

    Topics: Aminolevulinic Acid; Female; Humans; Male; Meningeal Neoplasms; Meningioma; Skull Base Neoplasms

2014
Quantitative and qualitative 5-aminolevulinic acid-induced protoporphyrin IX fluorescence in skull base meningiomas.
    Neurosurgical focus, 2011, Volume: 30, Issue:5

    Topics: Aminolevulinic Acid; Diagnostic Imaging; Female; Humans; Meningeal Neoplasms; Meningioma; Middle Age

2011