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aminolevulinic acid and Neoplasm Metastasis

aminolevulinic acid has been researched along with Neoplasm Metastasis in 17 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Neoplasm Metastasis: The transfer of a neoplasm from one organ or part of the body to another remote from the primary site.

Research Excerpts

ExcerptRelevanceReference
"Urine samples from 58 patients with bladder cancer were centrifuged, and urine sediments were then treated with ALA."5.40Diagnostic approach for cancer cells in urine sediments by 5-aminolevulinic acid-based photodynamic detection in bladder cancer. ( Anai, S; Chihara, Y; Fujimoto, K; Hirao, Y; Kuwada, M; Miyake, M; Nakai, Y; Onishi, S; Tanaka, N; Tatsumi, Y, 2014)
"A photodynamic technique for human breast cancer detection founded upon the ability of tumour cells to rapidly accumulate the fluorescent product protoporphyrin IX (PpIX) has been applied to transgenic mouse models of mammary tumorigenesis."3.73Early neoplastic and metastatic mammary tumours of transgenic mice detected by 5-aminolevulinic acid-stimulated protoporphyrin IX accumulation. ( Beamer, WG; Dorward, AM; Duffy, TM; Fancher, KS; Walt, H, 2005)
"With regard to squamous cell carcinoma, treatment with 5-fluorouracil, methotrexate, interferon, and bleomycin are reviewed."2.47Intralesional agents in the management of cutaneous malignancy: a review. ( Good, LM; High, WA; Miller, MD, 2011)
"Urine samples from 58 patients with bladder cancer were centrifuged, and urine sediments were then treated with ALA."1.40Diagnostic approach for cancer cells in urine sediments by 5-aminolevulinic acid-based photodynamic detection in bladder cancer. ( Anai, S; Chihara, Y; Fujimoto, K; Hirao, Y; Kuwada, M; Miyake, M; Nakai, Y; Onishi, S; Tanaka, N; Tatsumi, Y, 2014)
"The mean number of metastases detected by the PDD was significantly higher than that of white light for FT821 (p=0."1.375-Aminolevulinic acid-induced fluorescence diagnosis of pleural malignant tumor. ( Ali, AH; Kakiuchi, S; Kenzaki, K; Kondo, K; Matsuoka, H; Nakagawa, Y; Sakiyama, S; Sekido, Y; Sone, S; Takizawa, H; Tangoku, A; Toba, H, 2011)
"Changes in the metastasis phenotypes previously found are likely to be ascribed to these differences."1.35Disorganisation of cytoskeleton in cells resistant to photodynamic treatment with decreased metastatic phenotype. ( Batlle, A; Blázquez, A; Casas, A; Di Venosa, G; Jaén, P; Juarranz, A; Mamone, L; Rodriguez, L; Sanz-Rodriguez, F; Stockert, JC, 2008)
"Head and neck cancer is highly invasive."1.34Photodynamic therapy suppresses the migration and invasion of head and neck cancer cells in vitro. ( Chen, CT; Lou, PJ; Wang, CP; Yang, TH, 2007)
"It has a tendency to metastasise to regional or distant sites after incomplete treatment."1.34Photodynamic therapy suppresses the migration and invasion of head and neck cancer cells in vitro. ( Chen, CT; Lou, PJ; Wang, CP; Yang, TH, 2007)
"A photodynamic technique for human breast cancer detection founded upon the ability of tumour cells to rapidly accumulate the fluorescent product protoporphyrin IX (PpIX) has been applied to transgenic mouse models of mammary tumorigenesis."1.33Early neoplastic and metastatic mammary tumours of transgenic mice detected by 5-aminolevulinic acid-stimulated protoporphyrin IX accumulation. ( Beamer, WG; Dorward, AM; Duffy, TM; Fancher, KS; Walt, H, 2005)
"Hepatocellular carcinoma was confirmed by the histological examination of several biopsies drawn from suspicious areas."1.31Feasibility and diagnostic impact of fluorescence-based diagnostic laparoscopy in hepatocellular carcinoma: a case report. ( Arnold, JC; Riemann, JF; Schneider, AR; Zöpf, T, 2002)
"The main tumor and the satellite metastases clearly showed intense fluorescence compared with unaffected liver parenchyma and other abdominal organs."1.31Feasibility and diagnostic impact of fluorescence-based diagnostic laparoscopy in hepatocellular carcinoma: a case report. ( Arnold, JC; Riemann, JF; Schneider, AR; Zöpf, T, 2002)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.88)18.2507
2000's10 (58.82)29.6817
2010's6 (35.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Omoto, K1
Matsuda, R1
Nakai, Y2
Tatsumi, Y2
Nakazawa, T1
Tanaka, Y1
Shida, Y1
Murakami, T1
Nishimura, F1
Nakagawa, I1
Motoyama, Y1
Nakamura, M1
Fujimoto, K2
Hiroyuki, N1
Suero Molina, EJ1
Ardon, H1
Schroeteler, J1
Klingenhöfer, M1
Holling, M1
Wölfer, J1
Fischer, B1
Stummer, W1
Ewelt, C1
Miyake, M1
Anai, S1
Kuwada, M1
Onishi, S1
Chihara, Y1
Tanaka, N1
Hirao, Y1
Casas, A2
Sanz-Rodriguez, F1
Di Venosa, G2
Rodriguez, L2
Mamone, L1
Blázquez, A1
Jaén, P1
Batlle, A2
Stockert, JC1
Juarranz, A2
Vanzulli, S1
Perotti, C1
Mamome, L1
Simian, M1
Pontiggia, O1
Hasan, T1
Good, LM1
Miller, MD1
High, WA1
Ali, AH1
Takizawa, H1
Kondo, K1
Matsuoka, H1
Toba, H1
Nakagawa, Y1
Kenzaki, K1
Sakiyama, S1
Kakiuchi, S1
Sekido, Y1
Sone, S1
Tangoku, A1
Cogno, IS1
Vittar, NB1
Lamberti, MJ1
Rivarola, VA1
Schneider, AR1
Zöpf, T1
Arnold, JC1
Riemann, JF1
Chan, JK1
Monk, BJ1
Cuccia, D1
Pham, H1
Kimel, S1
Gu, M1
Hammer-Wilson, MJ1
Liaw, LH1
Osann, K1
DiSaia, PJ1
Berns, M1
Tromberg, B1
Tadir, Y1
Córdoba, F1
Braathen, LR1
Weissenberger, J1
Vallan, C1
Kato, M1
Nakashima, I1
Weis, J1
von Felbert, V1
Dorward, AM1
Fancher, KS1
Duffy, TM1
Beamer, WG1
Walt, H1
Lisnjak, IO1
Kutsenok, VV1
Polyschuk, LZ1
Gorobets, OB1
Gamaleia, NF1
Wu, RW1
Chu, ES1
Yow, CM1
Chen, JY1
Yang, TH1
Chen, CT1
Wang, CP1
Lou, PJ1
Revenga Arranz, F1
Koenig, F1
Knittel, J1
Stepp, H1

Reviews

2 reviews available for aminolevulinic acid and Neoplasm Metastasis

ArticleYear
Intralesional agents in the management of cutaneous malignancy: a review.
    Journal of the American Academy of Dermatology, 2011, Volume: 64, Issue:2

    Topics: Aminolevulinic Acid; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Bleomycin; Carci

2011
[Medical treatment of epitheliomas].
    Revista clinica espanola, 1997, Volume: 197, Issue:12

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Antineoplastic Agents; Bowen's Disease; Carcinoma; Car

1997

Other Studies

15 other studies available for aminolevulinic acid and Neoplasm Metastasis

ArticleYear
Expression of peptide transporter 1 has a positive correlation in protoporphyrin IX accumulation induced by 5-aminolevulinic acid with photodynamic detection of non-small cell lung cancer and metastatic brain tumor specimens originating from non-small cel
    Photodiagnosis and photodynamic therapy, 2019, Volume: 25

    Topics: Aminolevulinic Acid; ATP Binding Cassette Transporter, Subfamily G, Member 2; Blotting, Western; Bra

2019
Aquaporin-4 in glioma and metastatic tissues harboring 5-aminolevulinic acid-induced porphyrin fluorescence.
    Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:10

    Topics: Adolescent; Adult; Aged; Aminolevulinic Acid; Animals; Aquaporin 1; Aquaporin 4; Brain Neoplasms; Fe

2013
Diagnostic approach for cancer cells in urine sediments by 5-aminolevulinic acid-based photodynamic detection in bladder cancer.
    Cancer science, 2014, Volume: 105, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Cell Line, Tumor; Cytologica

2014
Disorganisation of cytoskeleton in cells resistant to photodynamic treatment with decreased metastatic phenotype.
    Cancer letters, 2008, Oct-18, Volume: 270, Issue:1

    Topics: Actins; Aminolevulinic Acid; Animals; beta Catenin; Cadherins; Cell Adhesion; Cytoskeleton; Drug Res

2008
Decreased metastatic phenotype in cells resistant to aminolevulinic acid-photodynamic therapy.
    Cancer letters, 2008, Nov-28, Volume: 271, Issue:2

    Topics: Aminolevulinic Acid; Animals; Cell Adhesion; Drug Resistance, Neoplasm; Lung Neoplasms; Male; Mice;

2008
5-Aminolevulinic acid-induced fluorescence diagnosis of pleural malignant tumor.
    Lung cancer (Amsterdam, Netherlands), 2011, Volume: 74, Issue:1

    Topics: Aminolevulinic Acid; Animals; Carcinoma; Cell Line, Tumor; Fluorescence; Humans; Lung Neoplasms; Mes

2011
Optimization of photodynamic therapy response by survivin gene knockdown in human metastatic breast cancer T47D cells.
    Journal of photochemistry and photobiology. B, Biology, 2011, Sep-02, Volume: 104, Issue:3

    Topics: Aminolevulinic Acid; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Breast Neoplasms; Caspas

2011
Feasibility and diagnostic impact of fluorescence-based diagnostic laparoscopy in hepatocellular carcinoma: a case report.
    Endoscopy, 2002, Volume: 34, Issue:10

    Topics: Aged; Aminolevulinic Acid; Carcinoma, Hepatocellular; Female; Fluorescence; Humans; Laparoscopy; Lig

2002
Laparoscopic photodynamic diagnosis of ovarian cancer using 5-aminolevulinic acid in a rat model.
    Gynecologic oncology, 2002, Volume: 87, Issue:1

    Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Female; Fluorescence; Laparoscopy; Neoplasm Metastasis

2002
5-aminolaevulinic acid photodynamic therapy in a transgenic mouse model of skin melanoma.
    Experimental dermatology, 2005, Volume: 14, Issue:6

    Topics: Aminolevulinic Acid; Animals; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Fibrosis; Flo

2005
Early neoplastic and metastatic mammary tumours of transgenic mice detected by 5-aminolevulinic acid-stimulated protoporphyrin IX accumulation.
    British journal of cancer, 2005, Nov-14, Volume: 93, Issue:10

    Topics: Aminolevulinic Acid; Animals; Breast Neoplasms; Mice; Mice, Transgenic; Neoplasm Metastasis; Protopo

2005
Effect of photodynamic therapy on tumor angiogenesis and metastasis in mice bearing Lewis lung carcinoma.
    Experimental oncology, 2005, Volume: 27, Issue:4

    Topics: Aminolevulinic Acid; Animals; Carcinoma, Lewis Lung; Enzyme-Linked Immunosorbent Assay; Mice; Neopla

2005
Photodynamic effects on nasopharyngeal carcinoma (NPC) cells with 5-aminolevulinic acid or its hexyl ester.
    Cancer letters, 2006, Oct-08, Volume: 242, Issue:1

    Topics: Aminolevulinic Acid; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Dose-Response Relat

2006
Photodynamic therapy suppresses the migration and invasion of head and neck cancer cells in vitro.
    Oral oncology, 2007, Volume: 43, Issue:4

    Topics: Aminolevulinic Acid; Cell Line, Tumor; Cell Movement; Cell Survival; Collagen; Drug Combinations; Ex

2007
Diagnosing cancer in vivo.
    Science (New York, N.Y.), 2001, May-18, Volume: 292, Issue:5520

    Topics: Aminolevulinic Acid; Automation; Biopsy; Colonic Neoplasms; Endoscopy; Humans; Microscopy, Confocal;

2001