aminolevulinic acid has been researched along with Lymph Node Metastasis in 19 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-aminolevulinic acid (5-ALA)-based fluorescence diagnosis is now clinically applied for accurate and ultrarapid diagnosis of malignant lesions such as lymph node metastasis during surgery." | 3.83 | Simplified and optimized multispectral imaging for 5-ALA-based fluorescence diagnosis of malignant lesions. ( Harada, Y; Kato, Y; Matsuo, H; Minamikawa, T; Otsuji, E; Takamatsu, T; Tanaka, H; Yanagisawa, A, 2016) |
| "5-aminolevulinic acid (5-ALA) has been utilized for cancer diagnosis as a fluorescence probe." | 1.56 | 5-ALA-assistant automated detection of lymph node metastasis in gastric cancer patients. ( Harada, Y; Koshiishi, N; Matsumoto, T; Matsuo, H; Murayama, Y; Okochi, K; Otsuji, E; Takamatsu, T; Tanaka, H, 2020) |
| "Five-aminolevulinic acid (ALA) has received much attention recently as a new-generation photosensitive substance for photodynamic diagnosis (PDD)." | 1.40 | Photodynamic diagnosis using 5-aminolevulinic acid during gastrectomy for gastric cancer. ( Fukuhara, H; Hanazaki, K; Inoue, K; Kitagawa, H; Kobayashi, M; Maeda, H; Namikawa, T; Shiga, M; Shuin, T; Uemura, S, 2014) |
| "An orthotopic colon cancer model was prepared by inoculating the cecal wall of nude mice with HCA7, a human colon adenocarcinoma cell line." | 1.38 | Fluorescence diagnosis of metastatic lymph nodes using 5-aminolevulinic acid (5-ALA) in a mouse model of colon cancer. ( Hasegawa, S; Kato, S; Kawada, K; Kawamura, J; Sakai, Y, 2012) |
| "Lymph node metastasis is one of the most critical prognostic factors in patients with colorectal cancer." | 1.38 | Fluorescence diagnosis of metastatic lymph nodes using 5-aminolevulinic acid (5-ALA) in a mouse model of colon cancer. ( Hasegawa, S; Kato, S; Kawada, K; Kawamura, J; Sakai, Y, 2012) |
| "Aminolevulinic acid was administered at a concentration of 40 mg kg(-1)bodyweight 150-420 min prior to tumourectomy." | 1.31 | Photodynamic diagnosis of breast tumours after oral application of aminolevulinic acid. ( Allemann, J; Haller, U; Ladner, DP; Steiner, RA; Walt, H, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 7 (36.84) | 29.6817 |
| 2010's | 10 (52.63) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Naidoo, C | 1 |
| Kruger, CA | 1 |
| Abrahamse, H | 1 |
| Matsumoto, T | 1 |
| Murayama, Y | 5 |
| Matsuo, H | 2 |
| Okochi, K | 1 |
| Koshiishi, N | 1 |
| Harada, Y | 8 |
| Tanaka, H | 4 |
| Takamatsu, T | 8 |
| Otsuji, E | 7 |
| Koizumi, N | 4 |
| Harada, K | 2 |
| Beika, M | 4 |
| Yamaoka, Y | 3 |
| Dai, P | 4 |
| Komatsu, S | 1 |
| Kubota, T | 1 |
| Ichikawa, D | 1 |
| Okamoto, K | 2 |
| Yanagisawa, A | 4 |
| Namikawa, T | 1 |
| Inoue, K | 2 |
| Uemura, S | 1 |
| Shiga, M | 1 |
| Maeda, H | 1 |
| Kitagawa, H | 1 |
| Fukuhara, H | 1 |
| Kobayashi, M | 1 |
| Shuin, T | 1 |
| Hanazaki, K | 1 |
| Kuriu, Y | 1 |
| Nakanishi, M | 1 |
| Minamikawa, T | 4 |
| Asai, J | 1 |
| Takenaka, H | 1 |
| Katoh, N | 1 |
| Kato, Y | 1 |
| Ushimaru, Y | 1 |
| Fujiwara, Y | 1 |
| Kishi, K | 1 |
| Sugimura, K | 1 |
| Omori, T | 1 |
| Moon, JH | 1 |
| Yanagimoto, Y | 1 |
| Ohue, M | 1 |
| Yasui, M | 1 |
| Takahashi, H | 1 |
| Kobayashi, S | 1 |
| Akita, H | 1 |
| Miyoshi, N | 1 |
| Tomokuni, A | 1 |
| Sakon, M | 1 |
| Yano, M | 1 |
| Takizawa, H | 1 |
| Kondo, K | 1 |
| Toba, H | 1 |
| Kenzaki, K | 1 |
| Sakiyama, S | 1 |
| Tangoku, A | 1 |
| Imaizumi, K | 1 |
| Nakano, K | 1 |
| Kato, S | 1 |
| Kawamura, J | 1 |
| Kawada, K | 1 |
| Hasegawa, S | 1 |
| Sakai, Y | 1 |
| Frei, KA | 1 |
| Bonel, HM | 1 |
| Frick, H | 1 |
| Walt, H | 2 |
| Steiner, RA | 2 |
| Karl, A | 1 |
| Zaak, D | 1 |
| Tilki, D | 1 |
| Hungerhuber, E | 1 |
| Staehler, M | 1 |
| Denzinger, S | 1 |
| Stanislaus, P | 1 |
| Tritschler, S | 1 |
| Strittmatter, F | 1 |
| Stief, C | 1 |
| Burger, M | 1 |
| van Hillegersberg, R | 1 |
| Hekking-Weijma, JM | 1 |
| Wilson, JH | 1 |
| Edixhoven-Bosdijk, A | 1 |
| Kort, WJ | 1 |
| Itoh, Y | 1 |
| Ninomiya, Y | 1 |
| Henta, T | 1 |
| Tajima, S | 1 |
| Ishibashi, A | 1 |
| Moesta, KT | 1 |
| Ebert, B | 1 |
| Handke, T | 1 |
| Rinneberg, H | 1 |
| Schlag, PM | 1 |
| Ladner, DP | 1 |
| Allemann, J | 1 |
| Haller, U | 1 |
3 reviews available for aminolevulinic acid and Lymph Node Metastasis
| Article | Year |
|---|---|
Simultaneous Photodiagnosis and Photodynamic Treatment of Metastatic Melanoma.
Topics: Aminolevulinic Acid; Anthracenes; Biopsy, Fine-Needle; Drug Carriers; Early Diagnosis; Humans; Indol | 2019 |
Recent advances in photodynamic diagnosis of gastric cancer using 5-aminolevulinic acid.
Topics: Aminolevulinic Acid; Animals; Biomarkers, Tumor; Humans; Intraoperative Care; Luminescent Measuremen | 2016 |
Fluorescence as a concept in colorectal lymph node diagnosis.
Topics: Aminolevulinic Acid; Colorectal Neoplasms; Dihematoporphyrin Ether; Fluorescent Dyes; Heme; Humans; | 2000 |
1 trial available for aminolevulinic acid and Lymph Node Metastasis
| Article | Year |
|---|---|
Photodynamic detection of diseased axillary sentinel lymph node after oral application of aminolevulinic acid in patients with breast cancer.
Topics: Administration, Oral; Adult; Aminolevulinic Acid; Axilla; Breast Neoplasms; Female; Humans; Light; L | 2004 |
15 other studies available for aminolevulinic acid and Lymph Node Metastasis
| Article | Year |
|---|---|
5-ALA-assistant automated detection of lymph node metastasis in gastric cancer patients.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Fluorescent Dyes; Follo | 2020 |
Detection of metastatic lymph nodes using 5-aminolevulinic acid in patients with gastric cancer.
Topics: Aminolevulinic Acid; Fluorescence; Humans; Lymph Nodes; Lymphatic Metastasis; Neoplasm Staging; Phot | 2013 |
Photodynamic diagnosis using 5-aminolevulinic acid during gastrectomy for gastric cancer.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Feasibility Studies; Female; Fluorescence; Gast | 2014 |
Detection of lymph node metastases in human colorectal cancer by using 5-aminolevulinic acid-induced protoporphyrin IX fluorescence with spectral unmixing.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Colorectal Neoplasms; Female; Fluorescence; Hum | 2013 |
Photodynamic diagnosis of metastatic lymph nodes using 5-aminolevulinic acid in mouse squamous cell carcinoma.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Feasibility Studies; Fluorescence; Lymph Nod | 2014 |
Highly sensitive fluorescence detection of metastatic lymph nodes of gastric cancer with photo-oxidation of protoporphyrin IX.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cell Line, Tumor; Female; Human | 2016 |
Simplified and optimized multispectral imaging for 5-ALA-based fluorescence diagnosis of malignant lesions.
Topics: Aminolevulinic Acid; Biotransformation; Cell Line, Tumor; Collagen; Colorectal Neoplasms; Flavins; F | 2016 |
Prognostic Significance of Basing Treatment Strategy on the Results of Photodynamic Diagnosis in Advanced Gastric Cancer.
Topics: Aged; Aminolevulinic Acid; Antineoplastic Combined Chemotherapy Protocols; Ascites; Female; Gastrect | 2017 |
Fluorescence diagnosis of lymph node metastasis of lung cancer in a mouse model.
Topics: Administration, Oral; Aminolevulinic Acid; Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor | 2009 |
Precise detection of lymph node metastases in mouse rectal cancer by using 5-aminolevulinic acid.
Topics: Aminolevulinic Acid; Animals; Female; Green Fluorescent Proteins; Humans; Lymph Nodes; Lymphatic Met | 2009 |
Fluorescence diagnosis of metastatic lymph nodes using 5-aminolevulinic acid (5-ALA) in a mouse model of colon cancer.
Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Cell Line, Tumor; Colonic Neoplasms; Female; Fluoresce | 2012 |
[Diagnosis of urothelial carcinoma].
Topics: Aminolevulinic Acid; Biomarkers, Tumor; Biopsy; Carcinoma, Transitional Cell; Cystoscopy; Diagnostic | 2008 |
Adjuvant intraoperative photodynamic therapy diminishes the rate of local recurrence in a rat mammary tumour model.
Topics: Adenocarcinoma; Aminolevulinic Acid; Analysis of Variance; Animals; Chemotherapy, Adjuvant; Female; | 1995 |
Intraoperative detection of 5-aminolaevulinic acid-induced protoporphyrin fluorescence in lymph node metastases after oral administration.
Topics: Aged; Aminolevulinic Acid; Carcinoma, Squamous Cell; Female; Fluorescence; Humans; Intraoperative Pe | 2000 |
Photodynamic diagnosis of breast tumours after oral application of aminolevulinic acid.
Topics: Administration, Oral; Aminolevulinic Acid; Axilla; Breast Neoplasms; Feasibility Studies; Female; Hu | 2001 |