aminolevulinic acid has been researched along with Lung Neoplasms in 35 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Reduction of tumor stenosis, increase in quality of life, and phototoxicity were considered as primary objectives." | 2.70 | Comparison of 5-aminolaevulinic acid and porphyrin photosensitization for photodynamic therapy of malignant bronchial stenosis: a clinical pilot study. ( Anegg, U; Fell, B; Maier, A; Matzi, V; Pinter, H; Rehak, P; Smolle-Jüttner, FM; Tomaselli, F; Woltsche, M, 2002) |
| "Chemotherapy is one major treatment for lung cancer." | 1.56 | Chemo-photodynamic therapy by pulmonary delivery of gefitinib nanoparticles and 5-aminolevulinic acid for treatment of primary lung cancer of rats. ( Bao, J; Ge, Y; Jin, Y; Li, M; Li, Y; Wang, W; Wei, J; Zhang, M; Zhang, T, 2020) |
| "Lung cancer is a severe disease with high mortality." | 1.56 | Chemo-photodynamic therapy by pulmonary delivery of gefitinib nanoparticles and 5-aminolevulinic acid for treatment of primary lung cancer of rats. ( Bao, J; Ge, Y; Jin, Y; Li, M; Li, Y; Wang, W; Wei, J; Zhang, M; Zhang, T, 2020) |
| "5-Aminolevulinic acid (ALA) is a precursor of heme." | 1.39 | Antitumor effect of combination of hyperthermotherapy and 5-aminolevulinic acid (ALA). ( Abe, F; Hasegawa, T; Ishii, T; Kishi, A; Nakajima, M; Sadamoto, K; Suzuki, A; Takahashi, K; Tanaka, T; Uno, K; Yasuda, I, 2013) |
| "5-aminolevulinic acid (ALA) was used as a precursor of photosensitizer." | 1.37 | Evaluation of photodynamic therapy (PDT) procedures using microfluidic system. ( Brzozka, Z; Chudy, M; Dybko, A; Jedrych, E; Pawlicka, Z, 2011) |
| "The mean number of metastases detected by the PDD was significantly higher than that of white light for FT821 (p=0." | 1.37 | 5-Aminolevulinic acid-induced fluorescence diagnosis of pleural malignant tumor. ( Ali, AH; Kakiuchi, S; Kenzaki, K; Kondo, K; Matsuoka, H; Nakagawa, Y; Sakiyama, S; Sekido, Y; Sone, S; Takizawa, H; Tangoku, A; Toba, H, 2011) |
| " Lipophilicity is one of the key parameters defining the bioavailability of a topically applied drug." | 1.31 | 5-Aminolevulinic acid and its derivatives: physical chemical properties and protoporphyrin IX formation in cultured cells. ( Juillerat-Jeanneret, L; Lange, N; Uehlinger, P; van den Bergh, H; Wagnières, G; Zellweger, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (14.29) | 18.2507 |
| 2000's | 9 (25.71) | 29.6817 |
| 2010's | 16 (45.71) | 24.3611 |
| 2020's | 5 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Han, J | 1 |
| Yang, W | 1 |
| Li, Y | 2 |
| Li, J | 2 |
| Jiang, F | 1 |
| Xie, J | 1 |
| Huang, X | 1 |
| Yu, Y | 1 |
| Zou, Y | 1 |
| Yin, R | 1 |
| Kawamura, K | 1 |
| Matsushima, H | 1 |
| Sakai, H | 1 |
| Iwashima, A | 1 |
| Nakamura, S | 1 |
| Kojima, T | 1 |
| Sasaki, S | 1 |
| Shigenaga, T | 1 |
| Natsume, I | 1 |
| Sasaki, T | 1 |
| Ohsaki, Y | 3 |
| Iwanaga, K | 1 |
| Nishi, K | 1 |
| Mitsuishi, Y | 1 |
| Taniguchi, H | 1 |
| Sato, K | 1 |
| Yamauchi, M | 1 |
| Nakajima, M | 2 |
| Takahashi, K | 2 |
| Zhang, T | 1 |
| Bao, J | 1 |
| Zhang, M | 1 |
| Ge, Y | 1 |
| Wei, J | 1 |
| Wang, W | 1 |
| Li, M | 2 |
| Jin, Y | 2 |
| Xiao, Z | 1 |
| Zhuang, B | 1 |
| Zhang, G | 1 |
| Zuchowska, A | 1 |
| Jastrzebska, E | 1 |
| Chudy, M | 2 |
| Dybko, A | 2 |
| Brzozka, Z | 2 |
| Omoto, K | 1 |
| Matsuda, R | 1 |
| Nakai, Y | 1 |
| Tatsumi, Y | 1 |
| Nakazawa, T | 1 |
| Tanaka, Y | 1 |
| Shida, Y | 1 |
| Murakami, T | 1 |
| Nishimura, F | 1 |
| Nakagawa, I | 1 |
| Motoyama, Y | 1 |
| Nakamura, M | 1 |
| Fujimoto, K | 1 |
| Hiroyuki, N | 1 |
| Predina, JD | 1 |
| Runge, J | 1 |
| Newton, A | 1 |
| Mison, M | 1 |
| Xia, L | 1 |
| Corbett, C | 1 |
| Shin, M | 1 |
| Sulyok, LF | 1 |
| Durham, A | 1 |
| Nie, S | 1 |
| Singhal, S | 1 |
| Holt, D | 1 |
| Hasegawa, T | 1 |
| Ishii, T | 1 |
| Suzuki, A | 1 |
| Uno, K | 1 |
| Yasuda, I | 1 |
| Kishi, A | 1 |
| Sadamoto, K | 1 |
| Abe, F | 1 |
| Tanaka, T | 1 |
| Postiglione, I | 2 |
| Chiaviello, A | 1 |
| Aloj, SM | 2 |
| Palumbo, G | 2 |
| Penjweini, R | 1 |
| Loew, HG | 1 |
| Breit, P | 1 |
| Kratky, KW | 1 |
| Kitada, M | 2 |
| Matsuda, Y | 1 |
| Hayashi, S | 2 |
| Ishibashi, K | 2 |
| Hooda, J | 1 |
| Alam, M | 1 |
| Zhang, L | 1 |
| Barra, F | 1 |
| Casas, A | 1 |
| Di Venosa, G | 1 |
| Vanzulli, S | 1 |
| Perotti, C | 1 |
| Mamome, L | 1 |
| Rodriguez, L | 1 |
| Simian, M | 1 |
| Juarranz, A | 1 |
| Pontiggia, O | 1 |
| Hasan, T | 1 |
| Batlle, A | 1 |
| Tsai, T | 1 |
| Ji, HT | 1 |
| Chiang, PC | 1 |
| Chou, RH | 1 |
| Chang, WS | 1 |
| Chen, CT | 1 |
| Takizawa, H | 2 |
| Kondo, K | 2 |
| Toba, H | 2 |
| Kenzaki, K | 2 |
| Sakiyama, S | 2 |
| Tangoku, A | 2 |
| Čunderlíková, B | 1 |
| Vasovič, V | 1 |
| Sieber, F | 1 |
| Furre, T | 1 |
| Borgen, E | 1 |
| Nesland, JM | 1 |
| Peng, Q | 1 |
| Jedrych, E | 1 |
| Pawlicka, Z | 1 |
| Ali, AH | 1 |
| Matsuoka, H | 1 |
| Nakagawa, Y | 1 |
| Kakiuchi, S | 1 |
| Sekido, Y | 1 |
| Sone, S | 1 |
| Wu, RW | 1 |
| Yow, CM | 1 |
| Wong, CK | 1 |
| Lam, YH | 1 |
| Shrestha, TB | 1 |
| Seo, GM | 1 |
| Basel, MT | 1 |
| Kalita, M | 1 |
| Wang, H | 1 |
| Villanueva, D | 1 |
| Pyle, M | 1 |
| Balivada, S | 1 |
| Rachakatla, RS | 1 |
| Shinogle, H | 1 |
| Thapa, PS | 1 |
| Moore, D | 1 |
| Troyer, DL | 1 |
| Bossmann, SH | 1 |
| Sakai, M | 1 |
| Fujimoto, N | 1 |
| Ishii, K | 1 |
| Nakamura, H | 1 |
| Kaneda, Y | 1 |
| Awazu, K | 1 |
| Gamarra, F | 4 |
| Wagner, S | 1 |
| Al-Batran, S | 1 |
| Maier, I | 1 |
| Castro, M | 1 |
| Hautmann, H | 2 |
| Bergner, A | 1 |
| Baumgartner, R | 3 |
| Huber, RM | 4 |
| Prosst, RL | 1 |
| Winkler, S | 1 |
| Boehm, E | 1 |
| Gahlen, J | 1 |
| Lingk, P | 1 |
| Marmarova, A | 1 |
| Edelmann, M | 1 |
| Stepp, H | 2 |
| Robey, RW | 1 |
| Steadman, K | 1 |
| Polgar, O | 1 |
| Bates, SE | 1 |
| Campbell, DL | 2 |
| Fisher, ME | 1 |
| Johnson, JG | 2 |
| Rossi, FM | 1 |
| Campling, BG | 1 |
| Pottier, RH | 3 |
| Kennedy, JC | 3 |
| Gudgin-Dickson, EF | 1 |
| Forkert, PG | 1 |
| Schulz, H | 1 |
| Rick, K | 1 |
| Leberig, A | 1 |
| Roth, C | 1 |
| Li, G | 1 |
| Szewczuk, MR | 1 |
| Raptis, L | 1 |
| Weagle, GE | 1 |
| Al-Batran, SE | 1 |
| Astner, ST | 1 |
| Supthut, M | 1 |
| Brueckner, K | 1 |
| Welsch, U | 1 |
| Knuechel, R | 1 |
| Uehlinger, P | 1 |
| Zellweger, M | 1 |
| Wagnières, G | 1 |
| Juillerat-Jeanneret, L | 1 |
| van den Bergh, H | 1 |
| Lange, N | 1 |
| Maier, A | 1 |
| Tomaselli, F | 1 |
| Matzi, V | 1 |
| Woltsche, M | 1 |
| Anegg, U | 1 |
| Fell, B | 1 |
| Rehak, P | 1 |
| Pinter, H | 1 |
| Smolle-Jüttner, FM | 1 |
| Yasuda, S | 1 |
| Abe, M | 1 |
| Takahashi, N | 1 |
| Okazaki, S | 1 |
2 trials available for aminolevulinic acid and Lung Neoplasms
| Article | Year |
|---|---|
A Randomized Phase 2 Study of 5-Aminolevulinic Acid Hydrochloride and Sodium Ferrous Citrate for the Prevention of Nephrotoxicity Induced by Cisplatin-Based Chemotherapy of Lung Cancer.
Topics: Adult; Aged; Aminolevulinic Acid; Cisplatin; Citric Acid; Female; Humans; Lung Neoplasms; Male; Midd | 2022 |
Comparison of 5-aminolaevulinic acid and porphyrin photosensitization for photodynamic therapy of malignant bronchial stenosis: a clinical pilot study.
Topics: Adenocarcinoma; Aged; Aminolevulinic Acid; Bronchial Diseases; Carcinoma, Squamous Cell; Constrictio | 2002 |
33 other studies available for aminolevulinic acid and Lung Neoplasms
| Article | Year |
|---|---|
Combining Doxorubicin-Conjugated Polymeric Nanoparticles and 5-Aminolevulinic Acid for Enhancing Radiotherapy against Lung Cancer.
Topics: Aminolevulinic Acid; Cell Line, Tumor; Doxorubicin; Humans; Hydrogen-Ion Concentration; Lung Neoplas | 2022 |
5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) for acneform rash induced by erlotinib: A case report.
Topics: Acne Vulgaris; Aminolevulinic Acid; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Erlotinib Hydroc | 2022 |
Chemo-photodynamic therapy by pulmonary delivery of gefitinib nanoparticles and 5-aminolevulinic acid for treatment of primary lung cancer of rats.
Topics: Aminolevulinic Acid; Animals; Cell Line, Tumor; Gefitinib; Lung; Lung Neoplasms; Nanoparticles; Phot | 2020 |
Pulmonary delivery of cationic liposomal hydroxycamptothecin and 5-aminolevulinic acid for chemo-sonodynamic therapy of metastatic lung cancer.
Topics: Aminolevulinic Acid; Animals; Camptothecin; Cell Line, Tumor; Lung Neoplasms; Mice; Reactive Oxygen | 2021 |
3D lung spheroid cultures for evaluation of photodynamic therapy (PDT) procedures in microfluidic Lab-on-a-Chip system.
Topics: A549 Cells; Aminolevulinic Acid; Humans; Lab-On-A-Chip Devices; Lung Neoplasms; Photochemotherapy; P | 2017 |
Expression of peptide transporter 1 has a positive correlation in protoporphyrin IX accumulation induced by 5-aminolevulinic acid with photodynamic detection of non-small cell lung cancer and metastatic brain tumor specimens originating from non-small cel
Topics: Aminolevulinic Acid; ATP Binding Cassette Transporter, Subfamily G, Member 2; Blotting, Western; Bra | 2019 |
Evaluation of Aminolevulinic Acid-Derived Tumor Fluorescence Yields Disparate Results in Murine and Spontaneous Large Animal Models of Lung Cancer.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Non-Small-Cell Lung; Cell Line; Cell Line, Tumor; Disease M | 2019 |
Antitumor effect of combination of hyperthermotherapy and 5-aminolevulinic acid (ALA).
Topics: Aminolevulinic Acid; Animals; Carcinoma, Lewis Lung; Combined Modality Therapy; Female; Hyperthermia | 2013 |
5-aminolaevulinic acid/photo-dynamic therapy and gefitinib in non-small cell lung cancer cell lines: a potential strategy to improve gefitinib therapeutic efficacy.
Topics: Aminolevulinic Acid; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Death; | 2013 |
Optimizing the antitumor selectivity of PVP-Hypericin re A549 cancer cells and HLF normal cells through pulsed blue light.
Topics: Aminolevulinic Acid; Anthracenes; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Color; Dose-Re | 2013 |
Photodynamic diagnosis of pleural malignant lesions with a combination of 5-aminolevulinic acid and intrinsic fluorescence observation systems.
Topics: Aged; Aminolevulinic Acid; Female; Humans; Lung Neoplasms; Male; Middle Aged; Optical Imaging; Photo | 2015 |
Measurement of Heme Synthesis Levels in Mammalian Cells.
Topics: Aminolevulinic Acid; Animals; Carbon Radioisotopes; Cell Line; Cell Line, Tumor; HeLa Cells; Heme; H | 2015 |
Photodynamic therapy with 5-aminolaevulinic acid and DNA damage: unravelling roles of p53 and ABCG2.
Topics: Aminolevulinic Acid; ATP Binding Cassette Transporter, Subfamily G, Member 2; Carcinoma, Non-Small-C | 2016 |
Decreased metastatic phenotype in cells resistant to aminolevulinic acid-photodynamic therapy.
Topics: Aminolevulinic Acid; Animals; Cell Adhesion; Drug Resistance, Neoplasm; Lung Neoplasms; Male; Mice; | 2008 |
ALA-PDT results in phenotypic changes and decreased cellular invasion in surviving cancer cells.
Topics: Adenocarcinoma; Aminolevulinic Acid; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Down-Regulat | 2009 |
Fluorescence diagnosis of lymph node metastasis of lung cancer in a mouse model.
Topics: Administration, Oral; Aminolevulinic Acid; Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor | 2009 |
Hexaminolevulinate-mediated photodynamic purging of marrow grafts with murine breast carcinoma.
Topics: Aminolevulinic Acid; Animals; Bone Marrow; Bone Marrow Purging; Cell Line, Tumor; Female; Hematopoie | 2011 |
Evaluation of photodynamic therapy (PDT) procedures using microfluidic system.
Topics: Aminolevulinic Acid; Cell Line, Tumor; Dimethylpolysiloxanes; Humans; Lab-On-A-Chip Devices; Lung Ne | 2011 |
5-Aminolevulinic acid-induced fluorescence diagnosis of pleural malignant tumor.
Topics: Aminolevulinic Acid; Animals; Carcinoma; Cell Line, Tumor; Fluorescence; Humans; Lung Neoplasms; Mes | 2011 |
Photodynamic therapy (PDT) - Initiation of apoptosis via activation of stress-activated p38 MAPK and JNK signal pathway in H460 cell lines.
Topics: Aminolevulinic Acid; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Death; Cell | 2011 |
Stem cell-based photodynamic therapy.
Topics: Aminolevulinic Acid; Animals; Cell Line, Tumor; Cell Survival; Female; Fetal Blood; Imidazoles; Luci | 2012 |
In vitro investigation of efficient photodynamic therapy using a nonviral vector; hemagglutinating virus of Japan envelope.
Topics: Aminolevulinic Acid; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Delivery | 2012 |
Kinetics of 5-aminolevulinic acid-induced fluorescence in organ cultures of bronchial epithelium and tumor.
Topics: Aminolevulinic Acid; Analysis of Variance; Bronchi; Bronchial Neoplasms; Carcinoma, Non-Small-Cell L | 2002 |
Thoracoscopic fluorescence diagnosis (TFD) of pleural malignancies: experimental studies.
Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Female; Fluorescence; Humans; Lung Neoplasms; Mice; Mi | 2002 |
5-Aminolevulinic acid-induced fluorescence in bronchial tumours: dependency on the patterns of tumour invasion.
Topics: Aminolevulinic Acid; Bronchial Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Fluoresc | 2004 |
ABCG2-mediated transport of photosensitizers: potential impact on photodynamic therapy.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Aminolevulinic Acid; ATP Binding Cassette Transporter, Subfamil | 2005 |
Flow cytometric technique for quantitating cytotoxic response to photodynamic therapy.
Topics: Aminolevulinic Acid; Carcinoma, Small Cell; Cell Survival; Flow Cytometry; Humans; Lung Neoplasms; P | 1996 |
Detection of early stages of carcinogenesis in adenomas of murine lung by 5-aminolevulinic acid-induced protoporphyrin IX fluorescence.
Topics: Adenoma; Aminolevulinic Acid; Animals; Bronchoscopy; Fluorescence; Fluorometry; Lung; Lung Neoplasms | 1996 |
Inhalation of 5-aminolevulinic acid: a new technique for fluorescence detection of early stage lung cancer.
Topics: Administration, Inhalation; Aminolevulinic Acid; Animals; Dogs; Lung Neoplasms; Protoporphyrins; Spe | 1996 |
Rodent fibroblast model for studies of response of malignant cells to exogenous 5-aminolevulinic acid.
Topics: 3T3 Cells; Aminolevulinic Acid; Animals; Cell Line, Transformed; Cell Transformation, Neoplastic; Ce | 1999 |
Three-dimensional in vitro cocultivation of lung carcinoma cells with human bronchial organ culture as a model for bronchial carcinoma.
Topics: Aminolevulinic Acid; Bronchi; Bronchial Neoplasms; Carcinoma, Non-Small-Cell Lung; Coculture Techniq | 1999 |
5-Aminolevulinic acid and its derivatives: physical chemical properties and protoporphyrin IX formation in cultured cells.
Topics: Aminolevulinic Acid; Bronchi; Cell Line; Humans; Hydrogen-Ion Concentration; Kinetics; Lung Neoplasm | 2000 |
Photodynamic diagnosis of visceral pleural invasion of lung cancer with a combination of 5-aminolevulinic acid and autofluorescence observation systems.
Topics: Aminolevulinic Acid; Female; Humans; Levulinic Acids; Lung Neoplasms; Male; Neoplasm Invasiveness; O | 2017 |