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aminolevulinic acid and Local Neoplasm Recurrence

aminolevulinic acid has been researched along with Local Neoplasm Recurrence in 203 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Research Excerpts

ExcerptRelevanceReference
"OBJECT There is evidence that 5-aminolevulinic acid (ALA) facilitates greater extent of resection and improves 6-month progression-free survival in patients with high-grade gliomas."9.22A prospective Phase II clinical trial of 5-aminolevulinic acid to assess the correlation of intraoperative fluorescence intensity and degree of histologic cellularity during resection of high-grade gliomas. ( Berger, MS; Chang, S; Hervey-Jumper, SL; Lau, D; McDermott, MW; Molinaro, AM; Phillips, JJ, 2016)
"Several studies have shown that 5-aminolevulinic acid (5-ALA)-induced fluorescence cystoscopy improves the detection of superficial bladder cancer."9.12Clinically relevant reduction in risk of recurrence of superficial bladder cancer using 5-aminolevulinic acid-induced fluorescence diagnosis: 8-year results of prospective randomized study. ( Burger, M; Denzinger, S; Filbeck, T; Knuechel, R; Roessler, W; Walter, B; Wieland, WF, 2007)
" Search terms include "glioma" and "aminolevulinic acid"."9.055-Aminolevulinic acid for recurrent malignant gliomas: A systematic review. ( Broekx, S; De Vleeschouwer, S; Weyns, F, 2020)
"Fluorescence guided surgery (FGS) with five-aminolevulinic acid (5-ALA) is expected to revolutionize neurosurgical care of patients with high-grade gliomas (HGG)."9.015-Aminolevulinic acid fluorescence guided surgery for recurrent high-grade gliomas. ( Berger, MS; Chohan, MO, 2019)
"5-Aminolevulinic acid (5-ALA) has been approved as an intraoperative adjunct in glioma surgery in Europe, but not North America."8.93The role of 5-aminolevulinic acid in enhancing surgery for high-grade glioma, its current boundaries, and future perspectives: A systematic review. ( Bernstein, M; Hachem, LD; Klironomos, G; Mansouri, A; Mansouri, S; Vogelbaum, MA; Zadeh, G, 2016)
"We conducted a meta-analysis assessing the effect of photodynamic diagnosis (PDD) -guided transurethral resection of the bladder tumor (TURB) on the recurrence-free survival in patients with non-muscle invasive bladder cancer within prospective randomised trials that used 5-aminolevulinic acid as a photosensitizer."8.93[A systematic review and meta-analysis to assess the recurrence-free survival in non-muscle invasive bladder cancer after transurethral resection guided by 5-aminolevulinic acid-induced photodynamic diagnosis compared with white-light transurethral resect ( Evmenenko, AA; Rolevich, AI, 2016)
" This study investigated the efficacy of 5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) in destructing glioma stem cells (GSCs), including the mesenchymal subtype (MES-GSCs) demonstrated to have the lowest radio- and chemosensitivity."8.31Ablation efficacy of 5-aminolevulinic acid-mediated photodynamic therapy on human glioma stem cells. ( Fujishiro, T; Fukunaga, K; Furuse, M; Hiramatsu, R; Hosomi, R; Ikeda, N; Kajimoto, Y; Kawabata, S; Kuroiwa, T; Nakano, I; Nonoguchi, N; Omura, N; Park, Y; Wanibuchi, M; Yagi, R, 2023)
"Complete resection of glioblastoma via a supraorbital transciliary approach with 5-Aminolevulinic Acid use was performed without any complications, as demonstrated on postoperative MRI."8.31Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note. ( Aboukaïs, R; Bourgeois, P; Devalckeneer, A; Lejeune, JP; Reyns, N, 2023)
"Patient selection for transurethral resection of the bladder tumor using photodynamic diagnosis (PDD-TURBT) with oral 5-aminolevulinic acid (5-ALA) hydrochloride for non-muscle-invasive bladder cancer (NMIBC) is still unclear as to the best balance of risks (adverse events including hypotension) and benefits (reduction of intravesical recurrence)."8.31Risks and benefits of transurethral resection of the bladder tumor using photodynamic diagnosis with oral 5-aminolevulinic acid hydrochloride according to age and history of recurrence in patients with non-muscle invasive bladder cancer. ( Hirata, H; Hiroyoshi, T; Isoyama, N; Ito, H; Kobayashi, K; Matsumoto, H; Matsuyama, H; Misumi, T; Nakamura, K; Oka, S; Shiraishi, K, 2023)
"Photodynamic diagnosis (PDD) with administration of oral aminolevulinic acid (ALA) prior to transurethral resection of bladder tumor (TURBT) can now be used for non-muscle invasive bladder cancer (NMIBC) in clinical settings in Japan."8.12Real-world experience with 5-aminolevulinic acid for photodynamic diagnosis of bladder cancer (2nd report): Reduced bladder recurrence after PDD-TURBT. ( Fukuhara, H; Furihata, M; Inoue, K; Karashima, T; Kurabayashi, A; Lai, HW; Yamamoto, S, 2022)
"The aim of this study is to compare the use of 5-aminolevulinic acid (5-ALA) and sodium fluorescein (SF) in IV ventricular ependymoma (IVEP) surgical resection."8.125-aminolevulinic acid and sodium fluorescein in IV ventricle ependymoma surgery: preliminary experience comparing the two techniques. ( Becattini, E; Boschi, A; Buccoliero, A; Della Puppa, A; Lastrucci, G; Pisano, A, 2022)
"Introducing 5-aminolevulinic acid-photodynamic diagnosis into transurethral resection reduces residual bladder cancer and improves the cumulative intravesical recurrence-free survival in patients with non-muscle-invasive bladder cancer, indicating its possible therapeutic benefits."8.12Photodynamic diagnosis-assisted transurethral resection using oral 5-aminolevulinic acid decreases residual cancer and improves recurrence-free survival in patients with non-muscle-invasive bladder cancer. ( Harada, S; Honda, T; Kani, N; Kato, T; Matsuoka, Y; Okazoe, H; Sugimoto, M; Taoka, R; Tohi, Y; Tsunemori, H; Ueda, N; Yamasaki, M, 2022)
"To explore the therapeutic effect of topical 5-Aminolevulinic Acid photodynamic therapy (ALA-PDT) on laryngeal papillomatosis (LP) treatment."7.91Topical 5-aminolevulinic acid photodynamic therapy for laryngeal papillomatosistosis treatment. ( Cai, Q; Chen, R; Han, P; Huang, X; Liang, F; Lin, P; Luo, M, 2019)
"We determined whether photodynamic therapy after the oral administration of 5-aminolevulinic acid in patients with superficial bladder cancer that cannot be controlled by transurethral resection and intravesical bacillus Calmette-Guerin (BCG) immunotherapy would preserve the bladder, while stopping tumor progression."7.71Clinical experience with 5-aminolevulinic acid and photodynamic therapy for refractory superficial bladder cancer. ( Baumgartner, R; Hofstetter, A; Kriegmair, M; Stepp, H; Waidelich, R; Weninger, E, 2001)
"These initial clinical results suggest that photodynamic therapy with orally administered 5-aminolevulinic acid is effective as an organ preserving procedure for treating superficial bladder cancer even in patients with bacillus Calmette-Guerin refractory carcinoma."7.71Clinical experience with 5-aminolevulinic acid and photodynamic therapy for refractory superficial bladder cancer. ( Baumgartner, R; Hofstetter, A; Kriegmair, M; Stepp, H; Waidelich, R; Weninger, E, 2001)
"5-Aminolevulinic acid induced fluorescence endoscopy has outstanding sensitivity for detecting early stage bladder cancer."7.71Quantification of 5-aminolevulinic acid induced fluorescence improves the specificity of bladder cancer detection. ( Baumgartner, R; Frimberger, D; Hofstetter, A; Knüchel, R; Kriegmair, M; Schneede, P; Siebels, M; Stepp, H; Wagner, S; Zaak, D, 2001)
"In 25 cases (53 biopsies) of a history of or suspicion for bladder cancer 5-aminolevulinic acid induced fluorescence endoscopy and fluorescence image quantification were performed."7.71Quantification of 5-aminolevulinic acid induced fluorescence improves the specificity of bladder cancer detection. ( Baumgartner, R; Frimberger, D; Hofstetter, A; Knüchel, R; Kriegmair, M; Schneede, P; Siebels, M; Stepp, H; Wagner, S; Zaak, D, 2001)
"To report clinical experience with intravesical instillations of 5-aminolevulinic acid (ALA) for the photodynamic therapy of superficial bladder cancer and to assess any side-effects of the treatment."7.69Early clinical experience with 5-aminolevulinic acid for the photodynamic therapy of superficial bladder cancer. ( Baumgartner, R; Hofstetter, A; Kriegmair, M; Lumper, W; Waidelich, R, 1996)
"Evaluation of residual tumor rate and recurrence free survival were defined as the two primary study endpoints."6.71[Reducing the risk of superficial bladder cancer recurrence with 5-aminolevulinic acid-induced fluorescence diagnosis. Results of a 5-year study]. ( Filbeck, T; Knuechel, R; Pichlmeier, U; Rössler, W; Wieland, WF, 2003)
"5-Aminolevulinic acid (5-ALA) has been approved as an intraoperative adjunct in glioma surgery in Europe, but not North America."6.53The role of 5-aminolevulinic acid in enhancing surgery for high-grade glioma, its current boundaries, and future perspectives: A systematic review. ( Bernstein, M; Hachem, LD; Klironomos, G; Mansouri, A; Mansouri, S; Vogelbaum, MA; Zadeh, G, 2016)
"Gliomas are diffuse intra-axial lesions, which can be accessed by multiple surgical corridors for a same location depending on the surgeon's preference."5.91Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note. ( Aboukaïs, R; Bourgeois, P; Devalckeneer, A; Lejeune, JP; Reyns, N, 2023)
"This study compared tumor recurrence among NMIBC patients who underwent TURBT under either white light cystoscopy (WL) or PDD."5.72Real-world experience with 5-aminolevulinic acid for photodynamic diagnosis of bladder cancer (2nd report): Reduced bladder recurrence after PDD-TURBT. ( Fukuhara, H; Furihata, M; Inoue, K; Karashima, T; Kurabayashi, A; Lai, HW; Yamamoto, S, 2022)
"The frequency of recurrence in NMIBC patients (cumulative number of recurrences/cumulative number of follow-up days, number of recurrences/10,000 days), including progression to muscle-invasive bladder cancer (MIBC), was 12."5.72Real-world experience with 5-aminolevulinic acid for photodynamic diagnosis of bladder cancer (2nd report): Reduced bladder recurrence after PDD-TURBT. ( Fukuhara, H; Furihata, M; Inoue, K; Karashima, T; Kurabayashi, A; Lai, HW; Yamamoto, S, 2022)
"The frequency of recurrence was lower and the time to recurrence was longer in the PDD-TURBT group than in the WL-TURBT group."5.72Real-world experience with 5-aminolevulinic acid for photodynamic diagnosis of bladder cancer (2nd report): Reduced bladder recurrence after PDD-TURBT. ( Fukuhara, H; Furihata, M; Inoue, K; Karashima, T; Kurabayashi, A; Lai, HW; Yamamoto, S, 2022)
"5-aminolevulinic acid is a protoporphyrin IX precursor used for photodynamic diagnosis."5.72Photodynamic diagnosis-assisted transurethral resection using oral 5-aminolevulinic acid decreases residual cancer and improves recurrence-free survival in patients with non-muscle-invasive bladder cancer. ( Harada, S; Honda, T; Kani, N; Kato, T; Matsuoka, Y; Okazoe, H; Sugimoto, M; Taoka, R; Tohi, Y; Tsunemori, H; Ueda, N; Yamasaki, M, 2022)
"Cervical high-grade squamous intraepithelial lesions (HSIL), as pre-cancerous lesions, have a 5% chance of progressing to invasive cancer."5.72The effect of high-risk HPV E6/E7 mRNA on the efficacy of topical photodynamic therapy with 5-aminolevulinic acid for cervical high-grade squamous intraepithelial lesions. ( Cao, L; Qin, L; Shen, Y; Su, Y; Tang, Y; Wang, B; Wang, L; Zhang, L; Zhang, M; Zhang, T; Zhang, Y; Zhou, Y, 2022)
"Glioblastoma multiforme is a malignant neoplasia with a median survival of less than two years and without satisfactory therapeutic options."5.72The role of Shikonin in improving 5-aminolevulinic acid-based photodynamic therapy and chemotherapy on glioblastoma stem cells. ( Buchner, A; Lyu, C; Pohla, H; Schrader, I; Sroka, R; Stadlbauer, B; Stepp, H; Werner, M, 2022)
"Anal canal condylomata acuminata is a disease caused by the human papilloma virus."5.56Advanced application of holmium: YAG laser combined ALA-PDT for the treatment of refractory condylomata acuminata in anal canal. ( Liao, C; Sun, X; Wang, X; Zhang, G; Zhang, H; Zhang, L, 2020)
"A total of six cases of ulcerative squamous cell carcinoma were included in our study."5.56Efficacy and safety of 5-aminolevulinic acid photodynamic therapy for the treatment of ulcerative squamous cell carcinoma. ( Dong, L; Li, X; Lu, Y; Shen, X; Wang, Y; Zhang, J; Zhang, W, 2020)
"The detection rate of HPV infections was 76."5.51Topical 5-aminolevulinic acid photodynamic therapy for laryngeal papillomatosistosis treatment. ( Cai, Q; Chen, R; Han, P; Huang, X; Liang, F; Lin, P; Luo, M, 2019)
"To assess the efficacy of two treatment options for non-muscle-invasive bladder cancer (NMIBC): (1) transurethral resection (TUR) guided by fluorescence cystoscopy (FC) with the use of 5-aminolevulinic acid (5-ALA) and (2) single early instillation of doxorubicin in a single-center open-label prospective randomized study with a 2 × 2 factorial design."5.24Results of a prospective randomized study assessing the efficacy of fluorescent cystoscopy-assisted transurethral resection and single instillation of doxorubicin in patients with non-muscle-invasive bladder cancer. ( Krasny, SA; Minich, AA; Mokhort, AA; Polyakov, SL; Rolevich, AI; Sukonko, OG; Vasilevich, VY; Zhegalik, AG, 2017)
"OBJECT There is evidence that 5-aminolevulinic acid (ALA) facilitates greater extent of resection and improves 6-month progression-free survival in patients with high-grade gliomas."5.22A prospective Phase II clinical trial of 5-aminolevulinic acid to assess the correlation of intraoperative fluorescence intensity and degree of histologic cellularity during resection of high-grade gliomas. ( Berger, MS; Chang, S; Hervey-Jumper, SL; Lau, D; McDermott, MW; Molinaro, AM; Phillips, JJ, 2016)
"The benefits of fluorescent light (FL) cystoscopy with 5-aminolevulinic acid (5-ALA) or hexaminolevulinate (HAL) in non-muscle-invasive bladder cancer (NMIBC) have been mentioned in many trials."5.12Effects of fluorescent light cystoscopy in non-muscle-invasive bladder cancer: A systematic review and meta-analysis. ( Liu, B; Ma, X; Shen, H; Sun, J, 2021)
"Several studies have shown that 5-aminolevulinic acid (5-ALA)-induced fluorescence cystoscopy improves the detection of superficial bladder cancer."5.12Clinically relevant reduction in risk of recurrence of superficial bladder cancer using 5-aminolevulinic acid-induced fluorescence diagnosis: 8-year results of prospective randomized study. ( Burger, M; Denzinger, S; Filbeck, T; Knuechel, R; Roessler, W; Walter, B; Wieland, WF, 2007)
"To report a phase-1 study of patients with recurrent superficial bladder cancer treated with photodynamic therapy (PDT) using sequential mitomycin C and 5-aminolaevulinic acid (ALA)."5.11A phase-1 study of sequential mitomycin C and 5-aminolaevulinic acid-mediated photodynamic therapy in recurrent superficial bladder carcinoma. ( Allman, R; Datta, SN; French, AJ; Mason, MD; Matthews, PN; Skyrme, RJ, 2005)
"Photodynamic therapy (PDT) using topical delta-aminolevulinic acid (delta-ALA) is an effective treatment for Bowen disease and certain basal cell carcinomas (BCCs), but its place in clinical practice remains to be established."5.09Photodynamic therapy for large or multiple patches of Bowen disease and basal cell carcinoma. ( MacKie, RM; McColl, JH; Moore, JV; Morton, CA; Whitehurst, C, 2001)
"One of the most valuable innovations in high-grade glioma surgery is 5-aminolevulinic acid (5-ALA)."5.055-Aminolevulinic Acid False Positives in Cerebral Neuro-Oncology: Not All That Is Fluorescent Is Tumor. A Case-Based Update and Literature Review. ( Altieri, R; Barresi, V; Della Pepa, GM; Ius, T; La Rocca, G; Marchese, E; Menna, G; Olivi, A; Sabatino, G, 2020)
" Search terms include "glioma" and "aminolevulinic acid"."5.055-Aminolevulinic acid for recurrent malignant gliomas: A systematic review. ( Broekx, S; De Vleeschouwer, S; Weyns, F, 2020)
"Fluorescence guided surgery (FGS) with five-aminolevulinic acid (5-ALA) is expected to revolutionize neurosurgical care of patients with high-grade gliomas (HGG)."5.015-Aminolevulinic acid fluorescence guided surgery for recurrent high-grade gliomas. ( Berger, MS; Chohan, MO, 2019)
"5-Aminolevulinic acid (5-ALA) has been approved as an intraoperative adjunct in glioma surgery in Europe, but not North America."4.93The role of 5-aminolevulinic acid in enhancing surgery for high-grade glioma, its current boundaries, and future perspectives: A systematic review. ( Bernstein, M; Hachem, LD; Klironomos, G; Mansouri, A; Mansouri, S; Vogelbaum, MA; Zadeh, G, 2016)
"We conducted a meta-analysis assessing the effect of photodynamic diagnosis (PDD) -guided transurethral resection of the bladder tumor (TURB) on the recurrence-free survival in patients with non-muscle invasive bladder cancer within prospective randomised trials that used 5-aminolevulinic acid as a photosensitizer."4.93[A systematic review and meta-analysis to assess the recurrence-free survival in non-muscle invasive bladder cancer after transurethral resection guided by 5-aminolevulinic acid-induced photodynamic diagnosis compared with white-light transurethral resect ( Evmenenko, AA; Rolevich, AI, 2016)
"The clinical benefit of photodynamic diagnosis (PDD) with 5-aminolevulinic acid or hexaminolevulinate in addition to white-light cystoscopy (WLC) in bladder cancer has been discussed controversially."4.86Photodynamic diagnosis in non-muscle-invasive bladder cancer: a systematic review and cumulative analysis of prospective studies. ( Jacqmin, D; Jichlinski, P; Jocham, D; Kausch, I; Montorsi, F; Sommerauer, M; Stenzl, A; Vonthein, R; Ziegler, A, 2010)
" This study investigated the efficacy of 5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) in destructing glioma stem cells (GSCs), including the mesenchymal subtype (MES-GSCs) demonstrated to have the lowest radio- and chemosensitivity."4.31Ablation efficacy of 5-aminolevulinic acid-mediated photodynamic therapy on human glioma stem cells. ( Fujishiro, T; Fukunaga, K; Furuse, M; Hiramatsu, R; Hosomi, R; Ikeda, N; Kajimoto, Y; Kawabata, S; Kuroiwa, T; Nakano, I; Nonoguchi, N; Omura, N; Park, Y; Wanibuchi, M; Yagi, R, 2023)
"Complete resection of glioblastoma via a supraorbital transciliary approach with 5-Aminolevulinic Acid use was performed without any complications, as demonstrated on postoperative MRI."4.31Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note. ( Aboukaïs, R; Bourgeois, P; Devalckeneer, A; Lejeune, JP; Reyns, N, 2023)
"Patient selection for transurethral resection of the bladder tumor using photodynamic diagnosis (PDD-TURBT) with oral 5-aminolevulinic acid (5-ALA) hydrochloride for non-muscle-invasive bladder cancer (NMIBC) is still unclear as to the best balance of risks (adverse events including hypotension) and benefits (reduction of intravesical recurrence)."4.31Risks and benefits of transurethral resection of the bladder tumor using photodynamic diagnosis with oral 5-aminolevulinic acid hydrochloride according to age and history of recurrence in patients with non-muscle invasive bladder cancer. ( Hirata, H; Hiroyoshi, T; Isoyama, N; Ito, H; Kobayashi, K; Matsumoto, H; Matsuyama, H; Misumi, T; Nakamura, K; Oka, S; Shiraishi, K, 2023)
"Photodynamic diagnosis (PDD) with administration of oral aminolevulinic acid (ALA) prior to transurethral resection of bladder tumor (TURBT) can now be used for non-muscle invasive bladder cancer (NMIBC) in clinical settings in Japan."4.12Real-world experience with 5-aminolevulinic acid for photodynamic diagnosis of bladder cancer (2nd report): Reduced bladder recurrence after PDD-TURBT. ( Fukuhara, H; Furihata, M; Inoue, K; Karashima, T; Kurabayashi, A; Lai, HW; Yamamoto, S, 2022)
"The aim of this study is to compare the use of 5-aminolevulinic acid (5-ALA) and sodium fluorescein (SF) in IV ventricular ependymoma (IVEP) surgical resection."4.125-aminolevulinic acid and sodium fluorescein in IV ventricle ependymoma surgery: preliminary experience comparing the two techniques. ( Becattini, E; Boschi, A; Buccoliero, A; Della Puppa, A; Lastrucci, G; Pisano, A, 2022)
"Introducing 5-aminolevulinic acid-photodynamic diagnosis into transurethral resection reduces residual bladder cancer and improves the cumulative intravesical recurrence-free survival in patients with non-muscle-invasive bladder cancer, indicating its possible therapeutic benefits."4.12Photodynamic diagnosis-assisted transurethral resection using oral 5-aminolevulinic acid decreases residual cancer and improves recurrence-free survival in patients with non-muscle-invasive bladder cancer. ( Harada, S; Honda, T; Kani, N; Kato, T; Matsuoka, Y; Okazoe, H; Sugimoto, M; Taoka, R; Tohi, Y; Tsunemori, H; Ueda, N; Yamasaki, M, 2022)
"5-aminolevulinic acid photodynamic therapy (ALA-PDT) is not only the first-line treatment for actinic keratosis (AK), but also demonstrated to improve photoaging during AK field treatment."4.02Long-term improvement on photoaging after ALA photodynamic therapy for actinic keratosis: A retrospective study. ( Liu, X; Shi, L; Wang, B; Wang, P; Wang, X; Zhang, G; Zhang, L; Zhao, Z; Zhou, Z, 2021)
"Photodynamic diagnosis (PDD) using 5-aminolevulinic acid (5-ALA) is expected to be useful in preventing oversight of non-muscle-invasive bladder cancer (NMIBC) and in reducing the intravesical recurrence rate after transurethral resection of bladder tumor (TURBT)."4.02[Initial Experience of Photodynamic Diagnosis-Assisted Transurethral Resection of Bladder Tumor (PDD-TURBT)]. ( Inoue, T; Kanda, H; Kato, M; Masui, S; Nishikawa, K; Sasaki, T; Sugimura, Y; Sugino, Y; Yoshio, Y, 2021)
"5-aminolevulinic acid (ALA)-mediated photodynamic therapy (PDT) is a reliable treatment for actinic keratosis (AK), though the concentration of 20 % is applied in most ALA-PDT for the treatment of AK, it was found that 10 % ALA could achieve similar outcome during clinical practice."3.96Comparison of efficacy, adverse effects and costs between 20 % ALA-PDT and 10 % ALA-PDT for the treatment of actinic keratosis in Chinese patients. ( Cao, Z; Shi, L; Wang, P; Wang, X; Zhang, G; Zhang, L; Zho, Z; Zhu, L, 2020)
"To explore the therapeutic effect of topical 5-Aminolevulinic Acid photodynamic therapy (ALA-PDT) on laryngeal papillomatosis (LP) treatment."3.91Topical 5-aminolevulinic acid photodynamic therapy for laryngeal papillomatosistosis treatment. ( Cai, Q; Chen, R; Han, P; Huang, X; Liang, F; Lin, P; Luo, M, 2019)
"Fluorescence-guided resection with 5-aminolevulinic acid (5-ALA), which has shown promising results in the resection of malignant gliomas, has been used for meningioma resection in an attempt to more clearly delineate the tumor margin."3.77Confocal microscopy for the histological fluorescence pattern of a recurrent atypical meningioma: case report. ( Harris, BT; Paulsen, KD; Roberts, DW; Valdes, PA; Whitson, WJ, 2011)
"We determined whether photodynamic therapy after the oral administration of 5-aminolevulinic acid in patients with superficial bladder cancer that cannot be controlled by transurethral resection and intravesical bacillus Calmette-Guerin (BCG) immunotherapy would preserve the bladder, while stopping tumor progression."3.71Clinical experience with 5-aminolevulinic acid and photodynamic therapy for refractory superficial bladder cancer. ( Baumgartner, R; Hofstetter, A; Kriegmair, M; Stepp, H; Waidelich, R; Weninger, E, 2001)
"These initial clinical results suggest that photodynamic therapy with orally administered 5-aminolevulinic acid is effective as an organ preserving procedure for treating superficial bladder cancer even in patients with bacillus Calmette-Guerin refractory carcinoma."3.71Clinical experience with 5-aminolevulinic acid and photodynamic therapy for refractory superficial bladder cancer. ( Baumgartner, R; Hofstetter, A; Kriegmair, M; Stepp, H; Waidelich, R; Weninger, E, 2001)
"5-Aminolevulinic acid induced fluorescence endoscopy has outstanding sensitivity for detecting early stage bladder cancer."3.71Quantification of 5-aminolevulinic acid induced fluorescence improves the specificity of bladder cancer detection. ( Baumgartner, R; Frimberger, D; Hofstetter, A; Knüchel, R; Kriegmair, M; Schneede, P; Siebels, M; Stepp, H; Wagner, S; Zaak, D, 2001)
"In 25 cases (53 biopsies) of a history of or suspicion for bladder cancer 5-aminolevulinic acid induced fluorescence endoscopy and fluorescence image quantification were performed."3.71Quantification of 5-aminolevulinic acid induced fluorescence improves the specificity of bladder cancer detection. ( Baumgartner, R; Frimberger, D; Hofstetter, A; Knüchel, R; Kriegmair, M; Schneede, P; Siebels, M; Stepp, H; Wagner, S; Zaak, D, 2001)
"The safety and efficacy of treating individuals who presented with multiple actinic keratosis (AK) lesions with 5-aminolevulinic acid (ALA) in combination with photodynamic therapy (PDT) were documented in a phase III trial."3.71Aminolevulinic acid hydrochloride with photodynamic therapy: efficacy outcomes and recurrence 4 years after treatment. ( Fowler, JF; Zax, RH, 2002)
"To report clinical experience with intravesical instillations of 5-aminolevulinic acid (ALA) for the photodynamic therapy of superficial bladder cancer and to assess any side-effects of the treatment."3.69Early clinical experience with 5-aminolevulinic acid for the photodynamic therapy of superficial bladder cancer. ( Baumgartner, R; Hofstetter, A; Kriegmair, M; Lumper, W; Waidelich, R, 1996)
" Any adverse event occurring during/after ALA application/irradiation as well as pain intensity were recorded at each visit."2.94Efficacy and safety of conventional versus daylight photodynamic therapy in children affected by multiple facial flat warts. ( Borgia, F; Cannavò, SP; Coppola, M; Giuffrida, R; Guarneri, F; Princiotta, R; Vaccaro, M, 2020)
"ALA-PDT is effective and safe for FFWs, with striking cosmetic results and no recurrence."2.94Efficacy and safety of conventional versus daylight photodynamic therapy in children affected by multiple facial flat warts. ( Borgia, F; Cannavò, SP; Coppola, M; Giuffrida, R; Guarneri, F; Princiotta, R; Vaccaro, M, 2020)
" None of the 12 adverse events during surveillance were serious."2.87Efficacy and Safety of Blue Light Flexible Cystoscopy with Hexaminolevulinate in the Surveillance of Bladder Cancer: A Phase III, Comparative, Multicenter Study. ( Bivalacqua, T; Daneshmand, S; DeCastro, J; Downs, T; Huang, W; Jones, J; Jones, JS; Kamat, A; Konety, B; Lotan, Y; O'Donnell, M; Patel, S; Pohar, K; Resnick, M; Schoenberg, M; Steinberg, G; Trabulsi, E; Woods, M, 2018)
"Office based blue light flexible cystoscopy significantly improves the detection of patients with recurrent bladder cancer and it is safe when used for surveillance."2.87Efficacy and Safety of Blue Light Flexible Cystoscopy with Hexaminolevulinate in the Surveillance of Bladder Cancer: A Phase III, Comparative, Multicenter Study. ( Bivalacqua, T; Daneshmand, S; DeCastro, J; Downs, T; Huang, W; Jones, J; Jones, JS; Kamat, A; Konety, B; Lotan, Y; O'Donnell, M; Patel, S; Pohar, K; Resnick, M; Schoenberg, M; Steinberg, G; Trabulsi, E; Woods, M, 2018)
"BACKGROUND Squamous cell carcinoma (SCC) is the second most common type of skin cancer, for which non- or mini-invasive treatment is of critical importance."2.84A Clinical Trial Using Attrition Combined with 5-Aminolevulinic Acids Based Photodynamic Therapy in Treating Squamous Cell Carcinoma. ( Dai, Y; Feng, W; Luo, X; Peng, J; Wang, T; Xiang, W; Zheng, J; Zhu, J, 2017)
"Diagnosis of bladder cancer is based on urine cytology and white-light cystoscopy (WLC) performed for patients with suspected bladder mass and÷or hematuria."2.84Improved diagnosis and long-term recurrence rate reduction for non-muscle-invasive bladder cancer patients undergoing fluorescent hexylaminolevulinate photodynamic diagnosis. ( Drăgoescu, NAM; Drăgoescu, PO; Drocaş, AI; Meşină, C; Mititelu, CD; Mitroi, G; Mohamed, G; Pănuş, A; Stănculescu, AD; Tomescu, PI; Tudorache, Ş, 2017)
"Patients with a history of bladder cancer were excluded."2.78Prospective randomized trial of hexylaminolevulinate photodynamic-assisted transurethral resection of bladder tumour (TURBT) plus single-shot intravesical mitomycin C vs conventional white-light TURBT plus mitomycin C in newly presenting non-muscle-invasi ( Chandra, A; Chatterton, K; Khan, MS; O'Brien, T; Ray, E; Thomas, K, 2013)
"Plaque-phase mycosis fungoides is among the most promising possibilities for the use of this treatment."2.75[Plaque-phase mycosis fungoides treated with photodynamic therapy: results from 12 patients]. ( De Las Heras, E; Fernández-Guarino, M; Harto, A; Jaén, P; Montull, C; Pérez-García, B, 2010)
"Evaluation of residual tumor rate and recurrence free survival were defined as the two primary study endpoints."2.71[Reducing the risk of superficial bladder cancer recurrence with 5-aminolevulinic acid-induced fluorescence diagnosis. Results of a 5-year study]. ( Filbeck, T; Knuechel, R; Pichlmeier, U; Rössler, W; Wieland, WF, 2003)
"Pain was assessed using a linear analogue scale from 0 to 10."2.70Photodynamic therapy for superficial bladder cancer under local anaesthetic. ( Betts, CD; Briggs, C; Clarke, NW; Gilhooley, A; Moore, JV; O'Flynn, KJ; Shackley, DC; Whitehurst, C, 2002)
"After a single treatment, 47 (85%) basal cell carcinomas showed a complete response at a follow-up time of at least 6 months."2.69Photodynamic therapy of superficial basal cell carcinomas using topical 5-aminolevulinic acid in a nanocolloid lotion. ( Hänggi, G; Hürlimann, AF; Panizzon, RG, 1998)
"5-Aminolevulinic acid (5-ALA) has been approved as an intraoperative adjunct in glioma surgery in Europe, but not North America."2.53The role of 5-aminolevulinic acid in enhancing surgery for high-grade glioma, its current boundaries, and future perspectives: A systematic review. ( Bernstein, M; Hachem, LD; Klironomos, G; Mansouri, A; Mansouri, S; Vogelbaum, MA; Zadeh, G, 2016)
"Erythroplasia of Queyrat (EOQ) is a squamous cell carcinoma in situ most commonly located on the glans penis or prepuce."2.53Erythroplasia of Queyrat treated by laser and light modalities: a systematic review. ( Jimenez, JJ; Lim, VM; Maranda, EL; Nguyen, AH; Shah, VV, 2016)
"Surgical excision (SE) is a first-line treatment for basal cell carcinoma (BCC)."2.53Photodynamic therapy versus surgical excision to basal cell carcinoma: meta-analysis. ( Han, J; Li, J; Lin, H; Luo, X; Ye, Z; Yu, J; Zhao, Y; Zou, Y, 2016)
"Non-muscle-invasive bladder cancer (NMIBC) is associated with a high recurrence risk, partly because of the persistence of lesions following transurethral resection of bladder tumour (TURBT) due to the presence of multiple lesions and the difficulty in identifying the exact extent and location of tumours using standard white-light cystoscopy (WLC)."2.50Clinical and cost effectiveness of hexaminolevulinate-guided blue-light cystoscopy: evidence review and updated expert recommendations. ( Babjuk, M; Gontero, P; Jacqmin, D; Karl, A; Kruck, S; Mariappan, P; Palou Redorta, J; Stenzl, A; van Velthoven, R; Witjes, JA; Zaak, D, 2014)
"In general, people with Bowen's disease have an excellent prognosis because the disease is typically slow-growing and responds favourably to treatment."2.49Interventions for cutaneous Bowen's disease. ( Bath-Hextall, FJ; Leonardi-Bee, J; Matin, RN; Wilkinson, D, 2013)
"Bowen's disease is the clinical term for in situ squamous cell carcinoma of the skin."2.49Interventions for cutaneous Bowen's disease. ( Bath-Hextall, FJ; Leonardi-Bee, J; Matin, RN; Wilkinson, D, 2013)
"Bladder cancer is the most common tumor of the urinary tract, with a worldwide incidence of 8."2.49Innovations in the endoscopic management of bladder cancer: is the era of white light cystoscopy over. ( Ambrosini, E; Frea, B; Giona, S; Gontero, P; Gurioli, A; Oderda, M; Peraldo, F; Soria, F, 2013)
"Residual tumour was significantly less often found after PDD (odds ratio: 0."2.46Photodynamic diagnosis in non-muscle-invasive bladder cancer: a systematic review and cumulative analysis of prospective studies. ( Jacqmin, D; Jichlinski, P; Jocham, D; Kausch, I; Montorsi, F; Sommerauer, M; Stenzl, A; Vonthein, R; Ziegler, A, 2010)
"Although bladder cancer occurs frequently, early diagnosis and complete removal of malignant lesions usually lead to good clinical outcomes."2.45Hexyl aminolevulinate fluorescence cystoscopy in bladder cancer. ( Kruck, S; Sievert, KD, 2009)
"Gliomas are diffuse intra-axial lesions, which can be accessed by multiple surgical corridors for a same location depending on the surgeon's preference."1.91Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note. ( Aboukaïs, R; Bourgeois, P; Devalckeneer, A; Lejeune, JP; Reyns, N, 2023)
"This study compared tumor recurrence among NMIBC patients who underwent TURBT under either white light cystoscopy (WL) or PDD."1.72Real-world experience with 5-aminolevulinic acid for photodynamic diagnosis of bladder cancer (2nd report): Reduced bladder recurrence after PDD-TURBT. ( Fukuhara, H; Furihata, M; Inoue, K; Karashima, T; Kurabayashi, A; Lai, HW; Yamamoto, S, 2022)
"The frequency of recurrence in NMIBC patients (cumulative number of recurrences/cumulative number of follow-up days, number of recurrences/10,000 days), including progression to muscle-invasive bladder cancer (MIBC), was 12."1.72Real-world experience with 5-aminolevulinic acid for photodynamic diagnosis of bladder cancer (2nd report): Reduced bladder recurrence after PDD-TURBT. ( Fukuhara, H; Furihata, M; Inoue, K; Karashima, T; Kurabayashi, A; Lai, HW; Yamamoto, S, 2022)
"The frequency of recurrence was lower and the time to recurrence was longer in the PDD-TURBT group than in the WL-TURBT group."1.72Real-world experience with 5-aminolevulinic acid for photodynamic diagnosis of bladder cancer (2nd report): Reduced bladder recurrence after PDD-TURBT. ( Fukuhara, H; Furihata, M; Inoue, K; Karashima, T; Kurabayashi, A; Lai, HW; Yamamoto, S, 2022)
"5-aminolevulinic acid is a protoporphyrin IX precursor used for photodynamic diagnosis."1.72Photodynamic diagnosis-assisted transurethral resection using oral 5-aminolevulinic acid decreases residual cancer and improves recurrence-free survival in patients with non-muscle-invasive bladder cancer. ( Harada, S; Honda, T; Kani, N; Kato, T; Matsuoka, Y; Okazoe, H; Sugimoto, M; Taoka, R; Tohi, Y; Tsunemori, H; Ueda, N; Yamasaki, M, 2022)
"Cervical high-grade squamous intraepithelial lesions (HSIL), as pre-cancerous lesions, have a 5% chance of progressing to invasive cancer."1.72The effect of high-risk HPV E6/E7 mRNA on the efficacy of topical photodynamic therapy with 5-aminolevulinic acid for cervical high-grade squamous intraepithelial lesions. ( Cao, L; Qin, L; Shen, Y; Su, Y; Tang, Y; Wang, B; Wang, L; Zhang, L; Zhang, M; Zhang, T; Zhang, Y; Zhou, Y, 2022)
"Glioblastoma multiforme is a malignant neoplasia with a median survival of less than two years and without satisfactory therapeutic options."1.72The role of Shikonin in improving 5-aminolevulinic acid-based photodynamic therapy and chemotherapy on glioblastoma stem cells. ( Buchner, A; Lyu, C; Pohla, H; Schrader, I; Sroka, R; Stadlbauer, B; Stepp, H; Werner, M, 2022)
" We investigated the effects of aminolevulinic acid-based photodynamic therapy (ALA-PDT) combined with oral acitretin during therapy of refractory CA in the anal canal."1.72ALA-PDT combined with oral acitretin in the treatment of refractory condyloma acuminatum in anal canal. ( Chen, N; Cheng, Q; Lei, X; Li, J; Tang, H; Wu, J; Zeng, Q; Zhang, L, 2022)
" ALA-PDT group with 51 patients was given ALA-PDT treatment, and ALA-PDT plus acitretin group with 50 patients was given ALA-PDT treatment combined with oral acitretin."1.72ALA-PDT combined with oral acitretin in the treatment of refractory condyloma acuminatum in anal canal. ( Chen, N; Cheng, Q; Lei, X; Li, J; Tang, H; Wu, J; Zeng, Q; Zhang, L, 2022)
"ALA-PDT combined with oral acitretin is effective and safe in the treatment of refractory CA in anal canal, and with further study may become an option for these patients."1.72ALA-PDT combined with oral acitretin in the treatment of refractory condyloma acuminatum in anal canal. ( Chen, N; Cheng, Q; Lei, X; Li, J; Tang, H; Wu, J; Zeng, Q; Zhang, L, 2022)
" The adverse reactions after PDT were mild, mainly manifested as increased vaginal secretions or burning/tingling."1.72Evaluation of the efficacy and safety of 5-aminolevulinic acid-mediated photodynamic therapy in women with high-risk HPV persistent infection after cervical conization. ( Huang, Y; Jia, L; Liu, X; Liu, Y; Wang, L; Zhang, J; Zhang, Y, 2022)
"Complete neurosurgical resection of intracranial meningiomas is essential to avoid residual tumor tissue and thus minimize the risk of tumor recurrence."1.62High Diagnostic Accuracy of Visible 5-ALA Fluorescence in Meningioma Surgery According to Histopathological Analysis of Tumor Bulk and Peritumoral Tissue. ( Kiesel, B; Knosp, E; Makolli, J; Mercea, PA; Millesi, M; Mischkulnig, M; Roetzer, T; Rössler, K; Wadiura, LI; Wais, J; Widhalm, G, 2021)
"Glioblastoma is the most severe form of brain cancer."1.62Isolation and initial characterization of human glioblastoma cells resistant to photodynamic therapy. ( Caputto, BL; Caverzán, MD; Milla Sanabria, LN; Palacios, RE; Prucca, CG; Rivarola, VA; Rodríguez, LB; Vilchez, ML, 2021)
" This study aimed to evaluate the efficacy and adverse effects of 5-aminolevulinic acid (ALA)-PDT in VEN treatment with a long-term follow-up."1.62Safety and effectiveness of 5-aminolevulinic acid photodynamic therapy combined with fractional micro-plasma radio-frequency treatment for verrucous epidermal nevus: A retrospective study with long-term follow-up. ( Chen, P; Dai, S; Guo, J; He, S; Huang, X; Li, Q; Shen, J; Zeng, K; Zhu, M, 2021)
"To evaluate the value of Wood's lamp examination combined with 5-aminolevulinic acid (5-ALA) photodynamic therapy (PDT) to determine positive tumor margins in patients with extramammary Paget's disease (EMPD) before surgery."1.62The application of Wood's lamp combined with 5-aminolevulinic acid for defining tumor margins in patients with extramammary Paget's disease. ( Fu, B; Li, J; Lou, Y; Song, C; Zhou, P, 2021)
" In the 5-ALA-PDT group, Wood's lamp examination combined with 5-ALA-PDT was used to trace the fluorescence range, and multipoint biopsy was performed according to the pathology to determine the final excision scope."1.62The application of Wood's lamp combined with 5-aminolevulinic acid for defining tumor margins in patients with extramammary Paget's disease. ( Fu, B; Li, J; Lou, Y; Song, C; Zhou, P, 2021)
"Wood's lamp examination combined with 5-ALA-PDT may predict tumor margins in EMPD."1.62The application of Wood's lamp combined with 5-aminolevulinic acid for defining tumor margins in patients with extramammary Paget's disease. ( Fu, B; Li, J; Lou, Y; Song, C; Zhou, P, 2021)
"Protoporphyrin IX (PpIX) is an endogenous photosensitizer (PS) widely used, obtained by the administration of precursors such as aminolevulinic acid and methyl aminolevulinate."1.56Use of dermograph for improvement of PpIX precursor's delivery in photodynamic therapy: Experimental and clinical pilot studies. ( Bagnato, VS; Fortunato, TC; Pratavieira, S; Requena, MB; Russignoli, PE; Salvio, AG; Vollet-Filho, JD, 2020)
"This study was designed to compare the efficacy, the adverse effects and the costs of 10 % and 20 % ALA-PDT for AK treatment."1.56Comparison of efficacy, adverse effects and costs between 20 % ALA-PDT and 10 % ALA-PDT for the treatment of actinic keratosis in Chinese patients. ( Cao, Z; Shi, L; Wang, P; Wang, X; Zhang, G; Zhang, L; Zho, Z; Zhu, L, 2020)
"We reviewed the records of patients who had received ALA-PDT in our department between January 1, 2012, and April 30, 2017, the efficacy, the adverse effects were recorded, and the costs were analyzed."1.56Comparison of efficacy, adverse effects and costs between 20 % ALA-PDT and 10 % ALA-PDT for the treatment of actinic keratosis in Chinese patients. ( Cao, Z; Shi, L; Wang, P; Wang, X; Zhang, G; Zhang, L; Zho, Z; Zhu, L, 2020)
"A total of 59 AK patients' records were analyzed for the efficacy, the adverse events, the recurrence and the costs."1.56Comparison of efficacy, adverse effects and costs between 20 % ALA-PDT and 10 % ALA-PDT for the treatment of actinic keratosis in Chinese patients. ( Cao, Z; Shi, L; Wang, P; Wang, X; Zhang, G; Zhang, L; Zho, Z; Zhu, L, 2020)
"10 % ALA-PDT has similar efficacy and adverse effects as 20 % ALA-PDT with lower costs."1.56Comparison of efficacy, adverse effects and costs between 20 % ALA-PDT and 10 % ALA-PDT for the treatment of actinic keratosis in Chinese patients. ( Cao, Z; Shi, L; Wang, P; Wang, X; Zhang, G; Zhang, L; Zho, Z; Zhu, L, 2020)
"Anal canal condylomata acuminata is a disease caused by the human papilloma virus."1.56Advanced application of holmium: YAG laser combined ALA-PDT for the treatment of refractory condylomata acuminata in anal canal. ( Liao, C; Sun, X; Wang, X; Zhang, G; Zhang, H; Zhang, L, 2020)
"A total of six cases of ulcerative squamous cell carcinoma were included in our study."1.56Efficacy and safety of 5-aminolevulinic acid photodynamic therapy for the treatment of ulcerative squamous cell carcinoma. ( Dong, L; Li, X; Lu, Y; Shen, X; Wang, Y; Zhang, J; Zhang, W, 2020)
"Bladder cancer is the eleventh most commonly diagnosed cancer worldwide."1.56Hexaminolevulinate blue light cystoscopy (Hal) assisted transurethral resection of the bladder tumour vs white light transurethral resection of the bladder tumour in non-muscle invasive bladder cancer (NMIBC) : a retrospective analysis. ( Bracale, U; Buonopane, R; Califano, G; Capece, M; Creta, M; Crocetto, F; Di Meo, S; Fusco, F; Imbimbo, C; Imperatore, V; La Rocca, R; Longo, N; Mirone, V; Napolitano, L; Palmieri, A; Sodo, M; Spirito, L; Verze, P, 2020)
"The purpose of this study is to investigate the clinical efficacy of Mohs surgery in combination with topical photodynamic therapy (PDT) for facial basal cell carcinoma."1.56Clinical efficacy of Mohs surgery combined with topical photodynamic therapy for facial basal cell carcinoma. ( Kou, H; Lu, Y; Wang, Y; Yang, Y; Zhang, J; Zhang, X, 2020)
"The detection rate of HPV infections was 76."1.51Topical 5-aminolevulinic acid photodynamic therapy for laryngeal papillomatosistosis treatment. ( Cai, Q; Chen, R; Han, P; Huang, X; Liang, F; Lin, P; Luo, M, 2019)
" The purpose of this article was to study the anti-tumor effect of ALA-PDT combined with limited excision in periocular basal cell carcinoma (BCC) and its role in improving the effect of the operation."1.51Ocular preservation through limited tumor excision combined with ALA-PDT in patients with periocular basal cell carcinoma. ( Kou, H; Li, G; Li, X; Lu, Y; Tan, L; Wang, Y; Zhang, J, 2019)
"In our study, 8 patients with periocular basal cell carcinoma were treated with topical aminolevulinic acid photodynamic therapy (ALA-PDT) combined with surgery."1.51Ocular preservation through limited tumor excision combined with ALA-PDT in patients with periocular basal cell carcinoma. ( Kou, H; Li, G; Li, X; Lu, Y; Tan, L; Wang, Y; Zhang, J, 2019)
"PDT in combination with limited surgery is a safe, effective and minimally-invasive approach for treating orbital BCC."1.51Ocular preservation through limited tumor excision combined with ALA-PDT in patients with periocular basal cell carcinoma. ( Kou, H; Li, G; Li, X; Lu, Y; Tan, L; Wang, Y; Zhang, J, 2019)
"Superficial basal cell carcinoma is a type of keratinocyte carcinoma that has increasing incidence and substantial morbidity."1.48Comparing Topical Treatments for Basal Cell Carcinoma. ( Shaw, FM; Weinstock, MA, 2018)
"5-aminolevulinic acid (5-ALA) is a natural precursor of protoporphyrin IX (PP IX), which possesses fluorescent properties and is more intensively accumulated in tumor cells than in normal tissue."1.43Laser biospectroscopy and 5-ALA fluorescence navigation as a helpful tool in the meningioma resection. ( Chumakova, AP; Golbin, DA; Goldberg, MF; Goryaynov, SA; Loschenov, VB; Okhlopkov, VA; Potapov, AA; Savelieva, TA; Shishkina, LV; Spallone, A; Varyukhina, MD, 2016)
"Mean residual tumor volume (range) after iMRI-assisted surgery [0."1.40Maximizing the extent of resection and survival benefit of patients in glioblastoma surgery: high-field iMRI versus conventional and 5-ALA-assisted surgery. ( Bisdas, S; Ebner, FH; Ernemann, U; Honegger, J; Naegele, T; Roder, C; Tatagiba, M, 2014)
"Analysis of residual tumor volumes, total resections and neurological outcomes demonstrate that iMRI may be significantly superior to 5-ALA and white-light surgery for glioblastomas at comparable peri- and postoperative morbidities."1.40Maximizing the extent of resection and survival benefit of patients in glioblastoma surgery: high-field iMRI versus conventional and 5-ALA-assisted surgery. ( Bisdas, S; Ebner, FH; Ernemann, U; Honegger, J; Naegele, T; Roder, C; Tatagiba, M, 2014)
"RESULTS Recurrent bladder cancer was detected in 11 of the 32 (34%) examinations."1.36Hexylaminolaevulinate fluorescence cystoscopy in patients previously treated with intravesical bacille Calmette-Guérin. ( Chandra, A; Chatterton, K; Dasgupta, P; Khan, MS; O'Brien, TS; Ray, ER; Thomas, K, 2010)
"5-aminolevulinic acid (5-ALA) has gained importance as an intraoperative photodynamic diagnostic agent for the extirpation of malignant gliomas."1.36Intraoperative 5-aminolevulinic-acid-induced fluorescence in meningiomas. ( Coluccia, D; Cordovi, S; Fandino, J; Fujioka, M; Landolt, H; Muroi, C, 2010)
"PDD during initial TUR-BT in T1G3 bladder cancer seems to reduce significantly the rate of recurrence in our study population."1.36Photodynamic diagnosis in patients with T1G3 bladder cancer: influence on recurrence rate. ( Karl, A; Knüchel, R; Stadler, T; Stanislaus, P; Stief, CG; Tritschler, S; Zaak, D, 2010)
"Five-aminolevulinic acid (ALA) is a drug which induces protoporphyrin IX accumulation in malignant gliomas and has been explored for fluorescence-guided resections of these tumors."1.35Long-sustaining response in a patient with non-resectable, distant recurrence of glioblastoma multiforme treated by interstitial photodynamic therapy using 5-ALA: case report. ( Baumgartner, R; Beck, T; Beyer, W; Etminan, N; Herms, J; Kreth, FW; Mehrkens, JH; Obermeier, A; Stepp, H; Stummer, W; Tonn, JC, 2008)
"A total of 279 patients with suspected bladder tumors underwent transurethral resection using FD in addition to WL cystoscopy."1.31Do patients profit from 5-aminolevulinic acid-induced fluorescence diagnosis in transurethral resection of bladder carcinoma? ( Filbeck, T; Knuechel, R; Pichlmeier, U; Roessler, W; Wieland, WF, 2002)
"A total of 13 squamous cell carcinomas were treated, including 10 nasal planum lesions, two pinnal lesions and one eyelid lesion."1.31Photodynamic therapy of feline superficial squamous cell carcinoma using topical 5-aminolaevulinic acid. ( Dobson, JM; Langmack, K; Stell, AJ, 2001)
"This was first shown for cancer of the bladder."1.31[Fluorescent endoscopy superior to white light endoscopy. Detecting cancers of the urinary bladder earlier]. ( Zaak, D, 2002)
"The prognosis of superficial bladder cancer in terms of local recurrence and transformation into invasive cancer is related to the multiplicity of tumor sites and the concomitant presence of "flat" tumours, such as dysplasia and carcinoma in situ."1.30[The clinical value of fluorescence cystoscopy in the detection of superficial transitional epithelial cell carcinoma of the bladder]. ( Forrer, M; Graber, P; Guillou, L; Jichlinski, P; Leisinger, HJ; Mizeret, J; Schmidlin, F; Van den Bergh, H; Wagniéres, G, 1997)
"Following transurethral resection of bladder cancer, the fate of patients is clearly related to the presence or absence of precancerous or malignant lesions in the remaining mucosa."1.29[Photodynamic diagnosis of urothelial neoplasms after intravesicular instillation of 5-aminolevulinic acid]. ( Baumgartner, R; Ehsan, A; Hofstädter, F; Hofstetter, A; Knüchel, R; Kriegmair, M; Lumper, W; Steinbach, P, 1994)

Research

Studies (203)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (4.93)18.2507
2000's51 (25.12)29.6817
2010's81 (39.90)24.3611
2020's61 (30.05)2.80

Authors

AuthorsStudies
Zhang, T4
Hu, R1
Tang, Y3
Zhang, Y5
Qin, L3
Shen, Y4
Wang, B5
Zhang, L8
Cao, L3
Zhou, Y4
Su, Y4
Zhang, M5
Fukuhara, H2
Yamamoto, S1
Lai, HW1
Karashima, T2
Kurabayashi, A1
Furihata, M2
Inoue, K3
Boschi, A1
Lastrucci, G1
Pisano, A1
Becattini, E1
Buccoliero, A1
Della Puppa, A1
Taoka, R1
Matsuoka, Y1
Yamasaki, M1
Kani, N1
Honda, T1
Harada, S1
Tohi, Y1
Kato, T1
Okazoe, H1
Tsunemori, H1
Ueda, N1
Sugimoto, M1
Wang, L2
Werner, M1
Lyu, C1
Stadlbauer, B1
Schrader, I1
Buchner, A1
Stepp, H8
Sroka, R3
Pohla, H1
Zeng, Q2
Li, J4
Chen, N1
Tang, H1
Lei, X1
Wu, J1
Cheng, Q1
Liu, X2
Zhang, J5
Huang, Y1
Liu, Y1
Jia, L2
Omura, N1
Nonoguchi, N1
Fujishiro, T1
Park, Y1
Ikeda, N1
Kajimoto, Y2
Hosomi, R1
Yagi, R1
Hiramatsu, R1
Furuse, M1
Kawabata, S1
Fukunaga, K1
Kuroiwa, T2
Nakano, I1
Wanibuchi, M1
Zhang, C1
Zhou, M1
Yuan, S1
Shim, PJ3
Zeitouni, NC3
Zhao, H3
Peng, P3
Luo, Z3
Liu, H3
Sun, J4
Wang, X9
Jia, Q3
Yang, Z3
Devalckeneer, A2
Aboukaïs, R2
Bourgeois, P2
Reyns, N3
Lejeune, JP2
Kobayashi, K1
Matsuyama, H1
Oka, S1
Nakamura, K1
Misumi, T1
Hiroyoshi, T1
Ito, H1
Isoyama, N1
Hirata, H1
Matsumoto, H1
Shiraishi, K1
Bickels, J1
Gortzak, Y1
Sternheim, A1
Hoogeveen, F1
Blanker, MH1
Cauberg, E1
Steffens, MG1
Liang, F1
Han, P1
Chen, R1
Lin, P1
Luo, M1
Cai, Q1
Huang, X2
Yao, Y1
Shen, X2
Shi, L5
Tang, G1
Wu, L3
Requena, MB2
Russignoli, PE1
Vollet-Filho, JD1
Salvio, AG3
Fortunato, TC1
Pratavieira, S1
Bagnato, VS4
Zhang, G5
Cao, Z1
Wang, P4
Zhu, L2
Zho, Z1
Drejer, D1
Moltke, AL1
Nielsen, AM1
Lam, GW1
Jensen, JB1
Cai, H2
Ma, T2
Che, Y2
Wang, Y5
Wang, C1
Yin, G1
Radakovic, S1
Dangl, M1
Tanew, A1
Logan, IT1
Kulakov, EL1
Perrett, CM1
Chaabani, M1
Ben Lagha, I1
Ben Tanfous, A1
Koubaa, W1
Ben Brahim, E1
Fenniche, S1
Zaouak, A1
Hammami-Ghorbel, H1
La Rocca, G1
Sabatino, G1
Menna, G1
Altieri, R2
Ius, T1
Marchese, E1
Olivi, A1
Barresi, V1
Della Pepa, GM1
Liao, C2
Sun, X2
Zhang, H1
Stringasci, MD3
Barreto Requena, M1
Dong, L1
Li, X4
Zhang, W1
Lu, Y5
Pohar, KS1
Capece, M1
Spirito, L1
La Rocca, R1
Napolitano, L1
Buonopane, R1
Di Meo, S1
Sodo, M1
Bracale, U1
Longo, N1
Palmieri, A1
Fusco, F1
Verze, P1
Califano, G1
Crocetto, F1
Imbimbo, C1
Mirone, V1
Imperatore, V1
Creta, M1
Warsi, NM1
Zewude, R1
Karmur, B1
Pirouzmand, N1
Hachem, L1
Mansouri, A2
Broekx, S1
Weyns, F1
De Vleeschouwer, S1
Borgia, F1
Giuffrida, R1
Coppola, M1
Princiotta, R1
Vaccaro, M1
Guarneri, F1
Cannavò, SP1
Yan, L1
Ding, Z1
Sun, H1
Wadiura, LI1
Millesi, M1
Makolli, J1
Wais, J1
Kiesel, B1
Mischkulnig, M1
Mercea, PA1
Roetzer, T1
Knosp, E1
Rössler, K1
Widhalm, G1
Lotan, Y5
Chaplin, I1
Ahmadi, H1
Meng, X1
Roberts, S1
Ladi-Seyedian, S1
Bagrodia, A1
Margulis, V1
Woldu, S1
Daneshmand, S3
de Castro, CA1
Lombardi, W1
Inada, NM1
Zhang, GL1
Keyal, U1
Wang, PR1
Zhang, LL1
Bhatta, AK1
Wu, YH1
Fang, S1
Wang, XL1
Kremer, N1
Sherman, S1
Lapidoth, M1
Enk, CD1
Leshem, YA1
Mimouni, T1
Dudkiewicz, D1
Hodak, E1
Levi, A1
Zhang, X3
Yang, Y4
Kou, H3
Mizuno, M1
Mitsui, H1
Kajiyama, H1
Teshigawara, T1
Takahashi, K1
Ishii, T1
Ishizuka, M1
Nakajima, M1
Kikkawa, F1
Thomson, J1
Hogan, S1
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Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Blue Light Cystoscopy With Cysview® Registry[NCT02660645]4,400 participants (Anticipated)Observational [Patient Registry]2014-04-30Recruiting
A Prospective, Open, Comparative, Within Patient Controlled Multicenter Phase 3 Study of Blue Light Cystoscopy With Cysview and White Light Cystoscopy Using KARL STORZ D-Light C PDD Flexible Videoscope System in Detection of Bladder Cancer in Patients Wit[NCT02560584]Phase 3304 participants (Actual)Interventional2015-10-01Completed
Surgical Excision Versus Photodynamic Therapy and Topical 5-fluorouracil in Treatment of Bowen's Disease: a Multicenter Randomized Controlled Trial[NCT03909646]Phase 4250 participants (Anticipated)Interventional2019-05-27Recruiting
5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas[NCT05850377]90 participants (Anticipated)Observational2023-06-01Not yet recruiting
Efficacy of Atezolizumab Concurrent With Radiotherapy in Patients With Muscle-invasive Bladder cáncer (Study ATEZOBLADDERPRESERVE)[NCT04186013]Phase 239 participants (Anticipated)Interventional2019-09-18Active, not recruiting
A Randomized, Comparative, Controlled Phase III, Multicenter Study of Hexvix Fluorescence Cystoscopy and White Light Cystoscopy in the Detection Of Papillary Bladder Cancer and the Early Recurrence Rate in Patients With Bladder Cancer[NCT00233402]Phase 3789 participants (Actual)Interventional2005-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Proportion of Patients With Adverse Events Considered Causally Related to Cysview and/or Blue Light in the Surveillance Examination Compared With the OR Examination

(NCT02560584)
Timeframe: At time of cystoscopy procedure

InterventionParticipants (Count of Participants)
Surveillance Examination6
Surveillance + OR Examination3

Proportion of Patients With Histologically Confirmed Malignancy Where Malignancy is Only Detected With Blue Light Cystoscopy With Cysview and Not White Light Cystoscopy

In the subsection of patients with histologically confirmed malignancy, the proportion of patients detected only by the use of blue light cystoscopy with Cysview is measured. (NCT02560584)
Timeframe: At time of cystoscopy procedure

InterventionParticipants (Count of Participants)
Cysview Arm13

Proportion of Patients With One or More Carcinoma in Situ (CIS) Lesions Detected With Blue Light Cystoscopy With Cysview and None With White Light Cystoscopy

In the subsection of patients with histologically confirmed CIS, the proportion of patients detected only by blue light cystoscopy with Cysview is measured. (NCT02560584)
Timeframe: At time of cystoscopy procedure

InterventionParticipants (Count of Participants)
Cysview Arm9

Comparison of the Proportions of Patients in the White Light Cystoscopy and Hexvix Groups Who Underwent TURB for a Histologically-confirmed Ta or T1 Tumor Who Had a Recurrence ( CIS, Ta, T1 or T2-T4 Tumor) Within 9 Months.

(NCT00233402)
Timeframe: 9 months

Interventionpercentage of participants (Number)
Hexvix Group47.2
White Light Group56.1

Proportion of False Positive Lesions of Hexvix Cystoscopy and White Light Cystoscopy.

"The false detection rate for Hexvix cystoscopy was calculated as the total number of false positive lesions (i.e. lesions that were suspected with blue light but had negative histology according to the Standard of Truth central panel read) divided by the total number of lesions that were suspected with blue light (i.e., false positive divided by false positive plus true positive).~The corresponding false detection rates were also calculated for white light cystoscopy for the two groups separately." (NCT00233402)
Timeframe: Day 0

InterventionPercetange of lesion (Number)
Hexvix Group12
White Light Group10

Proportion of Patients With >= 1 Ta or T1 Tumor Detected With Blue Light and Not White Light

(NCT00233402)
Timeframe: Day 0

Interventionpercentage of participants (Number)
Hexvix Group16.4

Proportion of Patients With at Least One CIS Lesion Detected With Blue Light and None Seen With White Light.

(NCT00233402)
Timeframe: Day 0

Interventionpercentage of participants (Number)
Hexvix Fluorescence Cystoscopy31.7

Reviews

29 reviews available for aminolevulinic acid and Local Neoplasm Recurrence

ArticleYear
Comparison of hexaminolevulinate (HAL) -guided versus white light transurethral resection for NMIBC: A systematic review and meta-analysis of randomized controlled trials.
    Photodiagnosis and photodynamic therapy, 2023, Volume: 41

    Topics: Aminolevulinic Acid; Cystoscopy; Humans; Neoplasm Recurrence, Local; Neoplasm, Residual; Photochemot

2023
Comparison of hexaminolevulinate (HAL) -guided versus white light transurethral resection for NMIBC: A systematic review and meta-analysis of randomized controlled trials.
    Photodiagnosis and photodynamic therapy, 2023, Volume: 41

    Topics: Aminolevulinic Acid; Cystoscopy; Humans; Neoplasm Recurrence, Local; Neoplasm, Residual; Photochemot

2023
Comparison of hexaminolevulinate (HAL) -guided versus white light transurethral resection for NMIBC: A systematic review and meta-analysis of randomized controlled trials.
    Photodiagnosis and photodynamic therapy, 2023, Volume: 41

    Topics: Aminolevulinic Acid; Cystoscopy; Humans; Neoplasm Recurrence, Local; Neoplasm, Residual; Photochemot

2023
Comparison of hexaminolevulinate (HAL) -guided versus white light transurethral resection for NMIBC: A systematic review and meta-analysis of randomized controlled trials.
    Photodiagnosis and photodynamic therapy, 2023, Volume: 41

    Topics: Aminolevulinic Acid; Cystoscopy; Humans; Neoplasm Recurrence, Local; Neoplasm, Residual; Photochemot

2023
5-Aminolevulinic Acid False Positives in Cerebral Neuro-Oncology: Not All That Is Fluorescent Is Tumor. A Case-Based Update and Literature Review.
    World neurosurgery, 2020, Volume: 137

    Topics: Aminolevulinic Acid; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Diagnostic Errors; False Positive

2020
Blue Light Cystoscopy: Indications and Outcomes.
    Current urology reports, 2020, Apr-04, Volume: 21, Issue:5

    Topics: Administration, Intravesical; Aminolevulinic Acid; Cystoscopy; Disease Progression; Humans; Light; N

2020
The Cost-Effectiveness of 5-ALA in High-Grade Glioma Surgery: A Quality-Based Systematic Review.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2020, Volume: 47, Issue:6

    Topics: Aminolevulinic Acid; Brain Neoplasms; Canada; Cost-Benefit Analysis; Glioma; Humans; Neoplasm Recurr

2020
5-Aminolevulinic acid for recurrent malignant gliomas: A systematic review.
    Clinical neurology and neurosurgery, 2020, Volume: 195

    Topics: Aminolevulinic Acid; Brain Neoplasms; Glioma; Humans; Neoplasm Recurrence, Local; Neuronavigation; N

2020
Interventions for basal cell carcinoma of the skin.
    The Cochrane database of systematic reviews, 2020, 11-17, Volume: 11

    Topics: Adult; Aminolevulinic Acid; Antineoplastic Agents; Carcinoma, Basal Cell; Cryotherapy; Female; Human

2020
The application of physical pretreatment in photodynamic therapy for skin diseases.
    Lasers in medical science, 2021, Volume: 36, Issue:7

    Topics: Aminolevulinic Acid; Humans; Keratosis, Actinic; Neoplasm Recurrence, Local; Photochemotherapy; Phot

2021
The place of 5-aminolaevulinic acid-photodynamic therapy in the treatment landscape of urethral warts: A systematic review.
    Photodiagnosis and photodynamic therapy, 2021, Volume: 33

    Topics: Aminolevulinic Acid; Humans; Neoplasm Recurrence, Local; Papillomavirus Infections; Photochemotherap

2021
Effects of fluorescent light cystoscopy in non-muscle-invasive bladder cancer: A systematic review and meta-analysis.
    Photodiagnosis and photodynamic therapy, 2021, Volume: 34

    Topics: Aminolevulinic Acid; China; Cystoscopy; Humans; Neoplasm Recurrence, Local; Photochemotherapy; Photo

2021
Is interstitial photodynamic therapy for brain tumors ready for clinical practice? A systematic review.
    Photodiagnosis and photodynamic therapy, 2021, Volume: 36

    Topics: Aminolevulinic Acid; Brain Neoplasms; Humans; Neoplasm Recurrence, Local; Photochemotherapy; Photose

2021
[Progression of basic research, clinical application of photodynamic therapy and fluorescence-guided surgery in glioma treatment].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2018, Apr-28, Volume: 43, Issue:4

    Topics: Aminolevulinic Acid; Biomedical Research; Brain Neoplasms; Chemotherapy, Adjuvant; Fluorescence; Gli

2018
5-Aminolevulinic acid fluorescence guided surgery for recurrent high-grade gliomas.
    Journal of neuro-oncology, 2019, Volume: 141, Issue:3

    Topics: Aminolevulinic Acid; Brain Neoplasms; Fluorescent Dyes; Glioma; Humans; Neoplasm Grading; Neoplasm R

2019
Photodynamic diagnosis of non-muscle-invasive bladder cancer with hexaminolevulinate cystoscopy: a meta-analysis of detection and recurrence based on raw data.
    European urology, 2013, Volume: 64, Issue:5

    Topics: Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Humans; Kaplan-Meier Estimate; Neoplasm Invasive

2013
Interventions for cutaneous Bowen's disease.
    The Cochrane database of systematic reviews, 2013, Jun-24, Issue:6

    Topics: Aminolevulinic Acid; Aminoquinolines; Antineoplastic Agents; Bowen's Disease; Cryotherapy; Fluoroura

2013
Innovations in the endoscopic management of bladder cancer: is the era of white light cystoscopy over.
    Urologia, 2013, Volume: 80 Spec No 1

    Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell; Cystoscopy; False Negative Rea

2013
Hexaminolevulinate blue light cystoscopy: a review of its use in the diagnosis of bladder cancer.
    Molecular diagnosis & therapy, 2014, Volume: 18, Issue:1

    Topics: Aminolevulinic Acid; Clinical Trials as Topic; Cystoscopy; Humans; Meta-Analysis as Topic; Microscop

2014
Clinical and cost effectiveness of hexaminolevulinate-guided blue-light cystoscopy: evidence review and updated expert recommendations.
    European urology, 2014, Volume: 66, Issue:5

    Topics: Aminolevulinic Acid; Cost-Benefit Analysis; Cystectomy; Cystoscopy; Disease Progression; Disease-Fre

2014
The role of 5-aminolevulinic acid in enhancing surgery for high-grade glioma, its current boundaries, and future perspectives: A systematic review.
    Cancer, 2016, Aug-15, Volume: 122, Issue:16

    Topics: Aminolevulinic Acid; Brain Neoplasms; Glioma; Humans; Intraoperative Care; Magnetic Resonance Imagin

2016
Erythroplasia of Queyrat treated by laser and light modalities: a systematic review.
    Lasers in medical science, 2016, Volume: 31, Issue:9

    Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Humans; Lasers, Gas; Lasers, Solid-State; Low-Level L

2016
Photodynamic therapy versus surgical excision to basal cell carcinoma: meta-analysis.
    Journal of cosmetic dermatology, 2016, Volume: 15, Issue:4

    Topics: Aminolevulinic Acid; Carcinoma, Basal Cell; Humans; Neoplasm Recurrence, Local; Photochemotherapy; P

2016
[A systematic review and meta-analysis to assess the recurrence-free survival in non-muscle invasive bladder cancer after transurethral resection guided by 5-aminolevulinic acid-induced photodynamic diagnosis compared with white-light transurethral resect
    Urologiia (Moscow, Russia : 1999), 2016, Issue:4

    Topics: Aminolevulinic Acid; Cystectomy; Disease-Free Survival; Humans; Neoplasm Recurrence, Local; Photosen

2016
Hexyl aminolevulinate fluorescence cystoscopy in bladder cancer.
    Expert review of anticancer therapy, 2009, Volume: 9, Issue:8

    Topics: Aminolevulinic Acid; Clinical Trials as Topic; Cystoscopy; Fluorescent Dyes; Humans; Neoplasm Recurr

2009
Photodynamic diagnosis in non-muscle-invasive bladder cancer: a systematic review and cumulative analysis of prospective studies.
    European urology, 2010, Volume: 57, Issue:4

    Topics: Aminolevulinic Acid; Cystectomy; Cystoscopy; Disease-Free Survival; Evidence-Based Medicine; Humans;

2010
The role of hexylaminolaevulinate in the diagnosis and follow-up of non-muscle-invasive bladder cancer.
    BJU international, 2010, Volume: 105 Suppl 2

    Topics: Aminolevulinic Acid; Cystoscopy; Humans; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Photosen

2010
Hexaminolevulinate-guided fluorescence cystoscopy in the diagnosis and follow-up of patients with non-muscle-invasive bladder cancer: review of the evidence and recommendations.
    European urology, 2010, Volume: 57, Issue:4

    Topics: Aminolevulinic Acid; Cystectomy; Cystoscopy; Disease-Free Survival; Evidence-Based Medicine; Humans;

2010
Management of recurrent malignant glioma--neurosurgical strategies.
    Wiener medizinische Wochenschrift (1946), 2011, Volume: 161, Issue:1-2

    Topics: Aminolevulinic Acid; Brain Neoplasms; Combined Modality Therapy; Glioblastoma; Humans; Microscopy, F

2011
A review of laser and photodynamic therapy for the treatment of nonmelanoma skin cancer.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2004, Volume: 30, Issue:2 Pt 2

    Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Basal Cell; Clinical Trials as Topic; Humans; Ker

2004
["... The better to see you with"--phothodynamic diagnostic in superficial bladder cancer].
    Praxis, 2007, Oct-17, Volume: 96, Issue:42

    Topics: Administration, Intravesical; Aminolevulinic Acid; Animals; Carcinoma in Situ; Carcinoma, Papillary;

2007
[Fluorescence diagnosis and photodynamic therapy in urology].
    Aktuelle Urologie, 2007, Volume: 38, Issue:6

    Topics: Aminolevulinic Acid; Carcinoma in Situ; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II

2007

Trials

44 trials available for aminolevulinic acid and Local Neoplasm Recurrence

ArticleYear
DaBlaCa-11: Photodynamic Diagnosis in Flexible Cystoscopy-A Randomized Study With Focus on Recurrence.
    Urology, 2020, Volume: 137

    Topics: Aged; Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Female; Humans; Image Enhancement; Male; N

2020
Efficacy and safety of conventional versus daylight photodynamic therapy in children affected by multiple facial flat warts.
    Photodiagnosis and photodynamic therapy, 2020, Volume: 31

    Topics: Aged; Aminolevulinic Acid; Child; Humans; Neoplasm Recurrence, Local; Photochemotherapy; Photosensit

2020
A Clinical Trial Using Attrition Combined with 5-Aminolevulinic Acids Based Photodynamic Therapy in Treating Squamous Cell Carcinoma.
    Medical science monitor : international medical journal of experimental and clinical research, 2017, Mar-18, Volume: 23

    Topics: Aged; Aminolevulinic Acid; Apoptosis; Carcinoma, Squamous Cell; Combined Modality Therapy; Female; H

2017
Long-term outcomes of the randomized controlled trial comparing 5-aminolaevulinic acid and Photofrin photodynamic therapy for Barrett's oesophagus related neoplasia.
    Scandinavian journal of gastroenterology, 2018, Volume: 53, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Catheter Ablation; Dihematoporp

2018
Efficacy and Safety of Blue Light Flexible Cystoscopy with Hexaminolevulinate in the Surveillance of Bladder Cancer: A Phase III, Comparative, Multicenter Study.
    The Journal of urology, 2018, Volume: 199, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cystoscopy; Female; Humans; Male; Middle Aged;

2018
Efficacy and Safety of Blue Light Flexible Cystoscopy with Hexaminolevulinate in the Surveillance of Bladder Cancer: A Phase III, Comparative, Multicenter Study.
    The Journal of urology, 2018, Volume: 199, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cystoscopy; Female; Humans; Male; Middle Aged;

2018
Efficacy and Safety of Blue Light Flexible Cystoscopy with Hexaminolevulinate in the Surveillance of Bladder Cancer: A Phase III, Comparative, Multicenter Study.
    The Journal of urology, 2018, Volume: 199, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cystoscopy; Female; Humans; Male; Middle Aged;

2018
Efficacy and Safety of Blue Light Flexible Cystoscopy with Hexaminolevulinate in the Surveillance of Bladder Cancer: A Phase III, Comparative, Multicenter Study.
    The Journal of urology, 2018, Volume: 199, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cystoscopy; Female; Humans; Male; Middle Aged;

2018
Improved diagnosis and long-term recurrence rate reduction for non-muscle-invasive bladder cancer patients undergoing fluorescent hexylaminolevulinate photodynamic diagnosis.
    Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie, 2017, Volume: 58, Issue:4

    Topics: Aminolevulinic Acid; Female; Fluorescence; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Ph

2017
Ablative fractional laser-assisted photodynamic therapy provides superior long-term efficacy compared with standard methyl aminolevulinate photodynamic therapy for lower extremity Bowen disease.
    Journal of the American Academy of Dermatology, 2018, Volume: 79, Issue:5

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy, Needle; Bowen's Disease; Combined Modality The

2018
Patient-reported outcomes of blue-light flexible cystoscopy with hexaminolevulinate in the surveillance of bladder cancer: results from a prospective multicentre study.
    BJU international, 2019, Volume: 123, Issue:1

    Topics: Aged; Aminolevulinic Acid; Anxiety; Color; Cystoscopy; False Positive Reactions; Female; Fluorescent

2019
Fractionated 5-aminolevulinic acid photodynamic therapy after partial debulking versus surgical excision for nodular basal cell carcinoma: a randomized controlled trial with at least 5-year follow-up.
    Journal of the American Academy of Dermatology, 2013, Volume: 69, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Combined Modality Therap

2013
Prospective randomized trial of hexylaminolevulinate photodynamic-assisted transurethral resection of bladder tumour (TURBT) plus single-shot intravesical mitomycin C vs conventional white-light TURBT plus mitomycin C in newly presenting non-muscle-invasi
    BJU international, 2013, Volume: 112, Issue:8

    Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Antibiotics, Anti

2013
A randomized trial comparing methyl aminolaevulinate photodynamic therapy with and without Er:YAG ablative fractional laser treatment in Asian patients with lower extremity Bowen disease: results from a 12-month follow-up.
    The British journal of dermatology, 2014, Volume: 170, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Asian People; Bowen's Disease; Female; Follow-U

2014
Hexaminolevulinate-guided transurethral resection of non-muscle-invasive bladder cancer does not reduce the recurrence rates after a 2-year follow-up: a prospective randomized trial.
    International urology and nephrology, 2014, Volume: 46, Issue:5

    Topics: Aged; Aminolevulinic Acid; Color; Contrast Media; Cystoscopy; Disease-Free Survival; False Positive

2014
Optical coherence tomography imaging of non-melanoma skin cancer undergoing photodynamic therapy reveals subclinical residual lesions.
    Photodiagnosis and photodynamic therapy, 2014, Volume: 11, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Female; Humans; Keratosi

2014
Fractional laser-mediated photodynamic therapy of high-risk basal cell carcinomas--a randomized clinical trial.
    The British journal of dermatology, 2015, Volume: 172, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Combined Modality Therap

2015
A prospective Phase II clinical trial of 5-aminolevulinic acid to assess the correlation of intraoperative fluorescence intensity and degree of histologic cellularity during resection of high-grade gliomas.
    Journal of neurosurgery, 2016, Volume: 124, Issue:5

    Topics: Aminolevulinic Acid; Biopsy; Brain; Brain Neoplasms; Cell Count; Female; Glioblastoma; Glioma; Human

2016
Results of a prospective randomized study assessing the efficacy of fluorescent cystoscopy-assisted transurethral resection and single instillation of doxorubicin in patients with non-muscle-invasive bladder cancer.
    World journal of urology, 2017, Volume: 35, Issue:5

    Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Antibiotics, Anti

2017
Photodynamic diagnosis using 5-aminolevulinic acid for the detection of positive surgical margins during radical prostatectomy in patients with carcinoma of the prostate: a multicentre, prospective, phase 2 trial of a diagnostic procedure.
    European urology, 2009, Volume: 55, Issue:6

    Topics: Adenocarcinoma; Aged; Aminolevulinic Acid; Biopsy, Needle; Disease-Free Survival; Humans; Immunohist

2009
HAL blue-light cystoscopy in high-risk nonmuscle-invasive bladder cancer--re-TURBT recurrence rates in a prospective, randomized study.
    Urology, 2010, Volume: 76, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carbon Radioisotopes; Cystoscopy; Female; Human

2010
Hexaminolevulinate guided fluorescence cystoscopy reduces recurrence in patients with nonmuscle invasive bladder cancer.
    The Journal of urology, 2010, Volume: 184, Issue:5

    Topics: Aged; Aminolevulinic Acid; Carbon Radioisotopes; Cystoscopy; Female; Fluorescence; Humans; Male; Neo

2010
Hexaminolevulinate guided fluorescence cystoscopy reduces recurrence in patients with nonmuscle invasive bladder cancer.
    The Journal of urology, 2010, Volume: 184, Issue:5

    Topics: Aged; Aminolevulinic Acid; Carbon Radioisotopes; Cystoscopy; Female; Fluorescence; Humans; Male; Neo

2010
Hexaminolevulinate guided fluorescence cystoscopy reduces recurrence in patients with nonmuscle invasive bladder cancer.
    The Journal of urology, 2010, Volume: 184, Issue:5

    Topics: Aged; Aminolevulinic Acid; Carbon Radioisotopes; Cystoscopy; Female; Fluorescence; Humans; Male; Neo

2010
Hexaminolevulinate guided fluorescence cystoscopy reduces recurrence in patients with nonmuscle invasive bladder cancer.
    The Journal of urology, 2010, Volume: 184, Issue:5

    Topics: Aged; Aminolevulinic Acid; Carbon Radioisotopes; Cystoscopy; Female; Fluorescence; Humans; Male; Neo

2010
[Plaque-phase mycosis fungoides treated with photodynamic therapy: results from 12 patients].
    Actas dermo-sifiliograficas, 2010, Volume: 101, Issue:9

    Topics: Adrenal Cortex Hormones; Adult; Aminolevulinic Acid; Combined Modality Therapy; Female; Fluorescence

2010
Treatment changes and long-term recurrence rates after hexaminolevulinate (HAL) fluorescence cystoscopy: does it really make a difference in patients with non-muscle-invasive bladder cancer (NMIBC)?
    BJU international, 2012, Volume: 109, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Contrast Media; Cystoscopy; Disease Progression

2012
Long-term follow-up of metil aminolevulinate (MAL)-PDT in difficult-to-treat cutaneous Bowen's disease.
    International journal of dermatology, 2011, Volume: 50, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Bowen's Disease; Female; Follow-Up Studies; Hum

2011
The application of Levulan-based photodynamic therapy with imiquimod in the treatment of recurrent basal cell carcinoma.
    Medical science monitor : international medical journal of experimental and clinical research, 2012, Volume: 18, Issue:2

    Topics: Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Female; Humans; Male; Middle Aged; Neoplasm Recurr

2012
Photodynamic therapy of bladder cancer - a phase I study using hexaminolevulinate (HAL).
    Urologic oncology, 2013, Volume: 31, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cystoscopy; Dose-Response Relationship, Drug; D

2013
Long-term decrease in bladder cancer recurrence with hexaminolevulinate enabled fluorescence cystoscopy.
    The Journal of urology, 2012, Volume: 188, Issue:1

    Topics: Aged; Aminolevulinic Acid; Canada; Carbon Radioisotopes; Cystoscopy; Diagnosis, Differential; Europe

2012
Hexaminolevulinate-induced fluorescence versus white light during transurethral resection of noninvasive bladder tumor: does it reduce recurrences?
    Urology, 2012, Volume: 80, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cystectomy; Female; Fluorescence; Humans; Light

2012
Comparison of aminolevulinic acid and hexylester aminolevulinate induced protoporphyrin IX distribution in human bladder cancer.
    The Journal of urology, 2003, Volume: 170, Issue:2 Pt 1

    Topics: Administration, Intravesical; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Transitional

2003
[Reducing the risk of superficial bladder cancer recurrence with 5-aminolevulinic acid-induced fluorescence diagnosis. Results of a 5-year study].
    Der Urologe. Ausg. A, 2003, Volume: 42, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell

2003
[The impact of ALA (5-aminolevulinic acid)-fluorescence detection on the prognosis of superficial bladder cancer].
    Aktuelle Urologie, 2004, Volume: 35, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cystoscopy; Female; Fluorescence; Follow-Up Stu

2004
A phase-1 study of sequential mitomycin C and 5-aminolaevulinic acid-mediated photodynamic therapy in recurrent superficial bladder carcinoma.
    BJU international, 2005, Volume: 95, Issue:9

    Topics: Aged; Aminolevulinic Acid; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional C

2005
Photodynamic therapy for bladder cancer.
    The Lancet. Oncology, 2005, Volume: 6, Issue:8

    Topics: Aminolevulinic Acid; Antineoplastic Combined Chemotherapy Protocols; Humans; Mitomycin; Neoplasm Rec

2005
5-aminolaevulinic acid-induced fluorescence cystoscopy during transurethral resection reduces the risk of recurrence in stage Ta/T1 bladder cancer.
    BJU international, 2005, Volume: 96, Issue:6

    Topics: Aged; Aminolevulinic Acid; Carcinoma, Transitional Cell; Cystoscopy; Disease-Free Survival; Female;

2005
[Fluorescence cystoscopy in the diagnostics and treatment of superficial urinary bladder tumors].
    Casopis lekaru ceskych, 2005, Volume: 144 Suppl 2

    Topics: Aged; Aminolevulinic Acid; Carcinoma, Transitional Cell; Cystoscopy; Female; Fluorescence; Humans; M

2005
Long-term benefit of 5-aminolevulinic acid fluorescence assisted transurethral resection of superficial bladder cancer: 5-year results of a prospective randomized study.
    The Journal of urology, 2005, Volume: 174, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Austria; Carcinoma in Situ; Cystect

2005
Photodynamic therapy using a methyl ester of 5-aminolevulinic acid in recurrent Paget's disease of the vulva: a pilot study.
    Gynecologic oncology, 2006, Volume: 103, Issue:2

    Topics: Aged; Aminolevulinic Acid; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Paget Disease, E

2006
Clinically relevant reduction in risk of recurrence of superficial bladder cancer using 5-aminolevulinic acid-induced fluorescence diagnosis: 8-year results of prospective randomized study.
    Urology, 2007, Volume: 69, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Fluorescence; Follow-Up Studies; Humans

2007
Five-year follow-up of a randomized, prospective trial of topical methyl aminolevulinate photodynamic therapy vs surgery for nodular basal cell carcinoma.
    Archives of dermatology, 2007, Volume: 143, Issue:9

    Topics: Administration, Topical; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Female

2007
Photodynamic therapy of superficial basal cell carcinomas using topical 5-aminolevulinic acid in a nanocolloid lotion.
    Dermatology (Basel, Switzerland), 1998, Volume: 197, Issue:3

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma, Bas

1998
Photodynamic cystoscopy for detection of bladder tumors.
    Seminars in laparoscopic surgery, 1999, Volume: 6, Issue:2

    Topics: Adenocarcinoma, Papillary; Administration, Intravesical; Aminolevulinic Acid; Biopsy; Cystoscopy; Di

1999
Comparison of red and green light in the treatment of Bowen's disease by photodynamic therapy.
    The British journal of dermatology, 2000, Volume: 143, Issue:4

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Bowen's Disease; Follow-Up Studies; Humans; Middle Age

2000
Photodynamic therapy of residual or recurrent basal cell carcinoma after radiotherapy using topical 5-aminolevulinic acid or methylester aminolevulinic acid.
    Acta oncologica (Stockholm, Sweden), 2000, Volume: 39, Issue:5

    Topics: Administration, Topical; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Female

2000
Photodynamic therapy for large or multiple patches of Bowen disease and basal cell carcinoma.
    Archives of dermatology, 2001, Volume: 137, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Female;

2001
Fluorescence endoscopy with 5-aminolevulinic acid reduces early recurrence rate in superficial bladder cancer.
    The Journal of urology, 2001, Volume: 165, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Endoscopy; Female; Fluorescence; Humans; Male;

2001
Photodynamic therapy for superficial bladder cancer under local anaesthetic.
    BJU international, 2002, Volume: 89, Issue:7

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Anesthesia, Local; Anesthetics, Local; Carcinoma, Tran

2002

Other Studies

130 other studies available for aminolevulinic acid and Local Neoplasm Recurrence

ArticleYear
The effect of local photodynamic therapy with 5-aminolevulinic acid in the treatment of vaginal intraepithelial lesions with high-risk HPV infection.
    Photodiagnosis and photodynamic therapy, 2022, Volume: 37

    Topics: Aminolevulinic Acid; Female; Human papillomavirus 16; Human papillomavirus 18; Humans; Neoplasm Recu

2022
Real-world experience with 5-aminolevulinic acid for photodynamic diagnosis of bladder cancer (2nd report): Reduced bladder recurrence after PDD-TURBT.
    Photodiagnosis and photodynamic therapy, 2022, Volume: 38

    Topics: Aminolevulinic Acid; Cystoscopy; Humans; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Photoche

2022
5-aminolevulinic acid and sodium fluorescein in IV ventricle ependymoma surgery: preliminary experience comparing the two techniques.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2022, Volume: 43, Issue:8

    Topics: Adult; Aminolevulinic Acid; Brain Neoplasms; Ependymoma; Female; Fluorescein; Humans; Male; Neoplasm

2022
Photodynamic diagnosis-assisted transurethral resection using oral 5-aminolevulinic acid decreases residual cancer and improves recurrence-free survival in patients with non-muscle-invasive bladder cancer.
    Photodiagnosis and photodynamic therapy, 2022, Volume: 38

    Topics: Aminolevulinic Acid; Disease Progression; Humans; Neoplasm Recurrence, Local; Neoplasm, Residual; Ph

2022
The effect of high-risk HPV E6/E7 mRNA on the efficacy of topical photodynamic therapy with 5-aminolevulinic acid for cervical high-grade squamous intraepithelial lesions.
    Photodiagnosis and photodynamic therapy, 2022, Volume: 39

    Topics: Aminolevulinic Acid; Female; Human papillomavirus 16; Human papillomavirus 18; Humans; Neoplasm Recu

2022
The role of Shikonin in improving 5-aminolevulinic acid-based photodynamic therapy and chemotherapy on glioblastoma stem cells.
    Photodiagnosis and photodynamic therapy, 2022, Volume: 39

    Topics: Aminolevulinic Acid; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Naphthoquinones; Neopl

2022
Management of patients with positive margin after conization for high-grade cervical intraepithelial lesions.
    Lasers in surgery and medicine, 2022, Volume: 54, Issue:8

    Topics: Aminolevulinic Acid; Conization; Female; Humans; Margins of Excision; Neoplasm Recurrence, Local; Pa

2022
ALA-PDT combined with oral acitretin in the treatment of refractory condyloma acuminatum in anal canal.
    Photodiagnosis and photodynamic therapy, 2022, Volume: 40

    Topics: Acitretin; Aminolevulinic Acid; Anal Canal; Anus Diseases; Condylomata Acuminata; Humans; Neoplasm R

2022
Evaluation of the efficacy and safety of 5-aminolevulinic acid-mediated photodynamic therapy in women with high-risk HPV persistent infection after cervical conization.
    Photodiagnosis and photodynamic therapy, 2022, Volume: 40

    Topics: Aminolevulinic Acid; Conization; Female; Human papillomavirus 16; Human papillomavirus 18; Humans; M

2022
Ablation efficacy of 5-aminolevulinic acid-mediated photodynamic therapy on human glioma stem cells.
    Photodiagnosis and photodynamic therapy, 2023, Volume: 41

    Topics: Aminolevulinic Acid; Animals; Cell Line, Tumor; Glioma; Humans; Mice; Neoplasm Recurrence, Local; Ne

2023
The effect of local photodynamic therapy with 5-aminolevulinic acid in treating different grades of cervical intraepithelial neoplasia.
    Photodiagnosis and photodynamic therapy, 2022, Volume: 40

    Topics: Aminolevulinic Acid; Female; Humans; Neoplasm Recurrence, Local; Papillomavirus Infections; Photoche

2022
Long-term follow up of ALA 10% gel and red-light photodynamic therapy for the treatment of squamous cell carcinoma in situ.
    Photodiagnosis and photodynamic therapy, 2023, Volume: 41

    Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Follow-Up Studies; Humans; Neoplasm Recurrence, Local

2023
Long-term follow up of ALA 10% gel and red-light photodynamic therapy for the treatment of squamous cell carcinoma in situ.
    Photodiagnosis and photodynamic therapy, 2023, Volume: 41

    Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Follow-Up Studies; Humans; Neoplasm Recurrence, Local

2023
Long-term follow up of ALA 10% gel and red-light photodynamic therapy for the treatment of squamous cell carcinoma in situ.
    Photodiagnosis and photodynamic therapy, 2023, Volume: 41

    Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Follow-Up Studies; Humans; Neoplasm Recurrence, Local

2023
Long-term follow up of ALA 10% gel and red-light photodynamic therapy for the treatment of squamous cell carcinoma in situ.
    Photodiagnosis and photodynamic therapy, 2023, Volume: 41

    Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Follow-Up Studies; Humans; Neoplasm Recurrence, Local

2023
Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note.
    Neuro-Chirurgie, 2023, Volume: 69, Issue:1

    Topics: Aminolevulinic Acid; Brain Neoplasms; Glioblastoma; Glioma; Humans; Neoplasm Recurrence, Local; Temo

2023
Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note.
    Neuro-Chirurgie, 2023, Volume: 69, Issue:1

    Topics: Aminolevulinic Acid; Brain Neoplasms; Glioblastoma; Glioma; Humans; Neoplasm Recurrence, Local; Temo

2023
Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note.
    Neuro-Chirurgie, 2023, Volume: 69, Issue:1

    Topics: Aminolevulinic Acid; Brain Neoplasms; Glioblastoma; Glioma; Humans; Neoplasm Recurrence, Local; Temo

2023
Supraorbital transciliary approach as primary route to fronto-basal high grade glioma resection with 5-Aminolevulinic Acid use: Technical note.
    Neuro-Chirurgie, 2023, Volume: 69, Issue:1

    Topics: Aminolevulinic Acid; Brain Neoplasms; Glioblastoma; Glioma; Humans; Neoplasm Recurrence, Local; Temo

2023
Risks and benefits of transurethral resection of the bladder tumor using photodynamic diagnosis with oral 5-aminolevulinic acid hydrochloride according to age and history of recurrence in patients with non-muscle invasive bladder cancer.
    Photodiagnosis and photodynamic therapy, 2023, Volume: 41

    Topics: Aminolevulinic Acid; Cystectomy; Humans; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Non-Musc

2023
5-ALA photodynamic ablation of fibroblastic soft-tissue tumors.
    Photodiagnosis and photodynamic therapy, 2023, Volume: 42

    Topics: Aminolevulinic Acid; Fibromatosis, Aggressive; Humans; Neoplasm Recurrence, Local; Photochemotherapy

2023
Recurrence of non-muscle invasive bladder carcinoma after transurethral resection with hexaminolevulinate photodynamic diagnosis or regular cystoscopy.
    Scandinavian journal of urology, 2023, Dec-06, Volume: 58

    Topics: Aminolevulinic Acid; Carcinoma; Cystoscopy; Humans; Neoplasm Recurrence, Local; Retrospective Studie

2023
Topical 5-aminolevulinic acid photodynamic therapy for laryngeal papillomatosistosis treatment.
    Photodiagnosis and photodynamic therapy, 2019, Volume: 28

    Topics: Administration, Topical; Adult; Aminolevulinic Acid; Child; Child, Preschool; Female; Humans; Infant

2019
The combination of photodynamic therapy and fractional CO
    Photodiagnosis and photodynamic therapy, 2020, Volume: 29

    Topics: Aminolevulinic Acid; Carbon Dioxide; Humans; Laser Therapy; Leukoplakia, Oral; Neoplasm Recurrence,

2020
Use of dermograph for improvement of PpIX precursor's delivery in photodynamic therapy: Experimental and clinical pilot studies.
    Photodiagnosis and photodynamic therapy, 2020, Volume: 29

    Topics: Aminolevulinic Acid; Animals; Neoplasm Recurrence, Local; Photochemotherapy; Photosensitizing Agents

2020
Comparison of efficacy, adverse effects and costs between 20 % ALA-PDT and 10 % ALA-PDT for the treatment of actinic keratosis in Chinese patients.
    Photodiagnosis and photodynamic therapy, 2020, Volume: 31

    Topics: Aminolevulinic Acid; China; Humans; Keratosis, Actinic; Neoplasm Recurrence, Local; Photochemotherap

2020
Loop electrosurgical excision procedure followed by 5-aminolevulinic acid photodynamic therapy for cervical intraepithelial neoplasia, a report of six cases.
    Photodiagnosis and photodynamic therapy, 2020, Volume: 29

    Topics: Adult; Aminolevulinic Acid; Combined Modality Therapy; Electrosurgery; Female; Humans; Middle Aged;

2020
5-Aminolevulinic acid patch (Alacare) photodynamic therapy for actinic cheilitis: data from a prospective 12-month follow-up study on 21 patients.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2020, Volume: 34, Issue:9

    Topics: Aminolevulinic Acid; Cheilitis; Follow-Up Studies; Humans; Keratosis, Actinic; Neoplasm Recurrence,

2020
Sequential Treatment of Superficial Basal Cell Carcinomas With Topical Methyl Aminolevulinate Photodynamic Therapy and Imiquimod 5% Cream: A Retrospective Study of Clinical and Cosmetic Outcomes.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2020, Volume: 46, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Antineoplastic Combined Chemotherapy Protocols;

2020
Contribution of conventional photodynamic therapy in the treatment of primary cutaneous follicle center lymphoma.
    International journal of dermatology, 2020, Volume: 59, Issue:6

    Topics: Administration, Cutaneous; Aminolevulinic Acid; Back; Humans; Lymphoma, Follicular; Male; Middle Age

2020
Advanced application of holmium: YAG laser combined ALA-PDT for the treatment of refractory condylomata acuminata in anal canal.
    Photodiagnosis and photodynamic therapy, 2020, Volume: 30

    Topics: Aminolevulinic Acid; Anal Canal; Condylomata Acuminata; Holmium; Humans; Lasers, Solid-State; Neopla

2020
Photodynamic therapy in combination with surgery for the treatment of an extensive squamous cell carcinoma in situ - A case report.
    Photodiagnosis and photodynamic therapy, 2020, Volume: 30

    Topics: Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Humans; Neopl

2020
Efficacy and safety of 5-aminolevulinic acid photodynamic therapy for the treatment of ulcerative squamous cell carcinoma.
    Photodiagnosis and photodynamic therapy, 2020, Volume: 30

    Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Humans; Neoplasm Recurrence, Local; Photochemotherapy

2020
Hexaminolevulinate blue light cystoscopy (Hal) assisted transurethral resection of the bladder tumour vs white light transurethral resection of the bladder tumour in non-muscle invasive bladder cancer (NMIBC) : a retrospective analysis.
    Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica, 2020, Apr-06, Volume: 92, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cystoscopy; Disease-Free Survival; Female; Fluo

2020
Application of 5-aminolevulinic acid photodynamic therapy for vaginal intraepithelial neoplasia, a report of six cases.
    Photodiagnosis and photodynamic therapy, 2020, Volume: 31

    Topics: Aminolevulinic Acid; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Papillomavirus Infecti

2020
High Diagnostic Accuracy of Visible 5-ALA Fluorescence in Meningioma Surgery According to Histopathological Analysis of Tumor Bulk and Peritumoral Tissue.
    Lasers in surgery and medicine, 2021, Volume: 53, Issue:3

    Topics: Aminolevulinic Acid; Humans; Meningeal Neoplasms; Meningioma; Neoplasm Recurrence, Local; Retrospect

2021
Prospective evaluation of blue-light flexible cystoscopy with hexaminolevulinate in non-muscle-invasive bladder cancer.
    BJU international, 2021, Volume: 127, Issue:1

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Color; Cystoscopy; Disease Progression; Female

2021
High-risk HPV clearance and CIN 3 treated with MAL-PDT: A case report.
    Photodiagnosis and photodynamic therapy, 2020, Volume: 31

    Topics: Adult; Aminolevulinic Acid; Female; Humans; Neoplasm Recurrence, Local; Papillomavirus Infections; P

2020
Photodynamic therapy as an alternative treatment in patients with invasive cutaneous SCC where surgery is not feasible: Single center experience.
    Photodiagnosis and photodynamic therapy, 2020, Volume: 32

    Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Humans; Neoplasm Recurrence, Local; Photochemotherapy

2020
Self-administered daylight-activated photodynamic therapy for the treatment of hand eczema: A prospective proof-of-concept study.
    Dermatologic therapy, 2020, Volume: 33, Issue:6

    Topics: Adult; Aminolevulinic Acid; Eczema; Female; Humans; Keratosis, Actinic; Male; Neoplasm Recurrence, L

2020
Clinical efficacy of Mohs surgery combined with topical photodynamic therapy for facial basal cell carcinoma.
    Journal of cancer research and therapeutics, 2020, Volume: 16, Issue:5

    Topics: Adult; Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Combined Modality Therapy; Facial Neoplasms

2020
Efficacy of 5-aminolevulinic acid and LED photodynamic therapy in cervical intraepithelial neoplasia: A clinical trial.
    Photodiagnosis and photodynamic therapy, 2020, Volume: 32

    Topics: Aminolevulinic Acid; Female; Humans; Neoplasm Recurrence, Local; Photochemotherapy; Photosensitizing

2020
Isolation and initial characterization of human glioblastoma cells resistant to photodynamic therapy.
    Photodiagnosis and photodynamic therapy, 2021, Volume: 33

    Topics: Aminolevulinic Acid; Cell Line, Tumor; Glioblastoma; Humans; Neoplasm Recurrence, Local; Photochemot

2021
Photodynamic therapy as a treatment option for multiple pigmented basal cell carcinoma: Long-term follow-up results.
    Photodiagnosis and photodynamic therapy, 2021, Volume: 33

    Topics: Aminolevulinic Acid; Carcinoma, Basal Cell; Follow-Up Studies; Humans; Neoplasm Recurrence, Local; P

2021
Recurrent high-grade glioma surgery: a multimodal intraoperative protocol to safely increase extent of tumor resection and analysis of its impact on patient outcome.
    Neurosurgical focus, 2021, Volume: 50, Issue:1

    Topics: Aminolevulinic Acid; Brain Neoplasms; Glioma; Humans; Magnetic Resonance Imaging; Neoplasm Recurrenc

2021
Long-term improvement on photoaging after ALA photodynamic therapy for actinic keratosis: A retrospective study.
    Photodiagnosis and photodynamic therapy, 2021, Volume: 33

    Topics: Aminolevulinic Acid; Humans; Keratosis, Actinic; Neoplasm Recurrence, Local; Photochemotherapy; Phot

2021
Comparative histological and immunohistochemical changes in recurrent nodular basal cell carcinoma after photodynamic therapy.
    Dermatologic therapy, 2021, Volume: 34, Issue:2

    Topics: Aminolevulinic Acid; Carcinoma, Basal Cell; Humans; Neoplasm Recurrence, Local; Photochemotherapy; P

2021
Retrospective German claims data study on initial treatment of bladder carcinoma (BCa) by transurethral bladder resection (TURB): a comparative analysis of costs using standard white light- (WL-) vs. blue light- (BL-) TURB.
    World journal of urology, 2021, Volume: 39, Issue:8

    Topics: Aged; Aminolevulinic Acid; Carcinoma; Cystectomy; Cystoscopy; Female; Germany; Health Care Costs; He

2021
In vivo reflectance confocal microscopy for monitoring actinic keratosis treated with 5-aminolevulinic acid photodynamic therapy.
    Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 2021, Volume: 27, Issue:5

    Topics: Aminolevulinic Acid; Humans; Keratosis, Actinic; Microscopy, Confocal; Neoplasm Recurrence, Local; P

2021
Safety and effectiveness of 5-aminolevulinic acid photodynamic therapy combined with fractional micro-plasma radio-frequency treatment for verrucous epidermal nevus: A retrospective study with long-term follow-up.
    The Journal of dermatology, 2021, Volume: 48, Issue:8

    Topics: Aminolevulinic Acid; Follow-Up Studies; Humans; Neoplasm Recurrence, Local; Nevus, Sebaceous of Jada

2021
5-Aminolevulinic acid photodynamic therapy for early-stage lip squamous cell carcinoma.
    Photodiagnosis and photodynamic therapy, 2021, Volume: 35

    Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; China; Head and Neck Neoplasms; Humans; Lip; Neoplasm

2021
Combination curettage and modified ALA-PDT for multiple basal cell carcinomas of the face and head.
    Photodiagnosis and photodynamic therapy, 2021, Volume: 35

    Topics: Aminolevulinic Acid; Carcinoma, Basal Cell; Curettage; Hamartoma Syndrome, Multiple; Humans; Neoplas

2021
[Initial Experience of Photodynamic Diagnosis-Assisted Transurethral Resection of Bladder Tumor (PDD-TURBT)].
    Hinyokika kiyo. Acta urologica Japonica, 2021, Volume: 67, Issue:7

    Topics: Aged; Aminolevulinic Acid; Cystectomy; Cystoscopy; Humans; Neoplasm Invasiveness; Neoplasm Recurrenc

2021
The application of Wood's lamp combined with 5-aminolevulinic acid for defining tumor margins in patients with extramammary Paget's disease.
    Photodiagnosis and photodynamic therapy, 2021, Volume: 35

    Topics: Aminolevulinic Acid; Humans; Margins of Excision; Neoplasm Recurrence, Local; Paget Disease, Extrama

2021
Terapêutica Fotodinâmica com metil-aminolevulinato no tratamento de lesões refractárias de Micose Fungóide: resposta clínica e histológica mantida em dois doentes.
    Dermatology online journal, 2016, Sep-15, Volume: 22, Issue:9

    Topics: Administration, Cutaneous; Adrenal Cortex Hormones; Aged; Aminolevulinic Acid; Humans; Male; Mycosis

2016
Observational Studies Requested by European Health Authorities: Governmental Interference or an Enhancement of Everyday Urological Practice? The Hexvix® Observational Patients Evaluation Study as an Example of What to Expect.
    Urologia internationalis, 2017, Volume: 99, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cystectomy; Cystoscopy; Disease Progression; Di

2017
'Real-life experience': recurrence rate at 3 years with Hexvix
    World journal of urology, 2017, Volume: 35, Issue:12

    Topics: Administration, Intravesical; Aged; Aminolevulinic Acid; Cystectomy; Cystoscopy; Female; Humans; Kap

2017
5-Aminolevulinic Acid Guided Sampling of Glioblastoma Microenvironments Identifies Pro-Survival Signaling at Infiltrative Margins.
    Scientific reports, 2017, Nov-15, Volume: 7, Issue:1

    Topics: Adult; Aged; Aminolevulinic Acid; ErbB Receptors; Female; Fluorescence; Glioblastoma; Humans; Male;

2017
New combination strategy of photodynamic therapy and surgery in treating recurrent basal cell carcinoma, a case report.
    Photodiagnosis and photodynamic therapy, 2018, Volume: 21

    Topics: Aminolevulinic Acid; Carcinoma, Basal Cell; Humans; Male; Middle Aged; Mohs Surgery; Neoplasm Recurr

2018
Comparing Topical Treatments for Basal Cell Carcinoma.
    The Journal of investigative dermatology, 2018, Volume: 138, Issue:3

    Topics: Aminolevulinic Acid; Aminoquinolines; Carcinoma, Basal Cell; Fluorouracil; Humans; Imiquimod; Neopla

2018
Efficacy and tolerance of photodynamic therapy for vulvar Paget's disease: a multicentric retrospective study.
    European journal of dermatology : EJD, 2018, Jun-01, Volume: 28, Issue:3

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Follow-Up Studies; Humans; Middle Aged; Neopla

2018
Treatment of verrucous carcinoma in penis with topical aminolevulinic acid photodynamic therapy: An effective and safe treatment method.
    Photodiagnosis and photodynamic therapy, 2018, Volume: 24

    Topics: Adult; Aminolevulinic Acid; Carcinoma, Verrucous; Humans; Male; Middle Aged; Neoplasm Recurrence, Lo

2018
Is 5-ALA fluorescence of cerebral metastases a prognostic factor for local recurrence and overall survival?
    Journal of neuro-oncology, 2019, Volume: 141, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Brain Neoplasms; Female; Fluorescent Dyes; Foll

2019
High-Definition 3-Dimensional Exoscope for 5-ALA Glioma Surgery: 3-Dimensional Operative Video.
    Operative neurosurgery (Hagerstown, Md.), 2020, 03-01, Volume: 18, Issue:3

    Topics: Aminolevulinic Acid; Brain Neoplasms; Glioma; Humans; Japan; Male; Middle Aged; Neoplasm Recurrence,

2020
Ocular preservation through limited tumor excision combined with ALA-PDT in patients with periocular basal cell carcinoma.
    Photodiagnosis and photodynamic therapy, 2019, Volume: 27

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Combined Modality Therapy; Eye;

2019
Combination of electrocoagulation and photodynamic therapy for angiolymphoid hyperplasia with eosinophilia in the external ear.
    Photodiagnosis and photodynamic therapy, 2019, Volume: 27

    Topics: Aminolevulinic Acid; Angiolymphoid Hyperplasia with Eosinophilia; Combined Modality Therapy; Ear, Ex

2019
Subependymal spread of recurrent glioblastoma detected with the intraoperative use of 5-aminolevulinic acid: case report.
    Journal of neurosurgery, 2013, Volume: 118, Issue:6

    Topics: Aminolevulinic Acid; Diagnosis, Differential; Glioblastoma; Glioma, Subependymal; Humans; Intraopera

2013
Supraorbital trans-eyebrow craniotomy and fluorescence-guided resection of fronto-basal high grade gliomas.
    Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:9

    Topics: Aged; Aminolevulinic Acid; Basal Ganglia; Brain Neoplasms; Chemoradiotherapy, Adjuvant; Craniotomy;

2013
Fractional carbon dioxide laser improves nodular basal cell carcinoma treatment with photodynamic therapy with methyl 5-aminolevulinate.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2013, Volume: 39, Issue:8

    Topics: Aminolevulinic Acid; Carcinoma, Basal Cell; Combined Modality Therapy; Female; Humans; Lasers, Gas;

2013
Diffuse glioma detection.
    Journal of neurosurgery, 2013, Volume: 119, Issue:2

    Topics: Aminolevulinic Acid; Glioblastoma; Glioma, Subependymal; Humans; Male; Neoplasm Recurrence, Local; O

2013
Would the benefits of hexaminolevulinate fluorescence cystoscopy be eliminated if every patient received postoperative installation of intravesical chemotherapy?
    BJU international, 2013, Volume: 112, Issue:8

    Topics: Aminolevulinic Acid; Antibiotics, Antineoplastic; Cystoscopy; Female; Humans; Male; Mitomycin; Neopl

2013
Maximizing the extent of resection and survival benefit of patients in glioblastoma surgery: high-field iMRI versus conventional and 5-ALA-assisted surgery.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2014, Volume: 40, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Brain Neoplasms; Cohort Studies; Disease-Free S

2014
Complete remission of two patients with recurrent and wide spread extramammary Paget disease obtained from 5-aminolevulinic acid-based photodynamic therapy and imiquimod combination treatment.
    Photodiagnosis and photodynamic therapy, 2014, Volume: 11, Issue:3

    Topics: Aged; Aminolevulinic Acid; Aminoquinolines; Antineoplastic Agents; Drug Therapy, Combination; Genita

2014
No 5-ALA fluorescence seen in a recurrent papillary tumour of the pineal region (PTPR).
    Acta neurochirurgica, 2015, Volume: 157, Issue:2

    Topics: Adult; Aminolevulinic Acid; Brain Neoplasms; Female; Fluorescence; Humans; Neoplasm Recurrence, Loca

2015
5-ALA-induced fluorescence behavior of reactive tissue changes following glioblastoma treatment with radiation and chemotherapy.
    Acta neurochirurgica, 2015, Volume: 157, Issue:2

    Topics: Aged; Aminolevulinic Acid; Brain Neoplasms; Disease Progression; Female; Fluorescence; Glioblastoma;

2015
Feasibility of fluorescence-guided resection of recurrent gliomas using five-aminolevulinic acid: retrospective analysis of surgical and neurological outcome in 58 patients.
    Journal of neuro-oncology, 2015, Volume: 122, Issue:1

    Topics: Adult; Aged; Aminolevulinic Acid; Brain Neoplasms; Case-Control Studies; Feasibility Studies; Female

2015
Budget impact of incorporating one instillation of hexaminolevulinate hydrochloride blue-light cytoscopy in transurethral bladder tumour resection for patients with non-muscle-invasive bladder cancer in Sweden.
    BJU international, 2016, Volume: 117, Issue:6B

    Topics: Aminolevulinic Acid; Budgets; Costs and Cost Analysis; Cystoscopy; Disease Progression; Humans; Neop

2016
Two-fold illumination in topical 5-aminolevulinic acid (ALA)-mediated photodynamic therapy (PDT) for superficial basal cell carcinoma (sBCC): A retrospective case series and cohort study.
    Journal of the American Academy of Dermatology, 2016, Volume: 74, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Cohort Studies; Confiden

2016
Laser biospectroscopy and 5-ALA fluorescence navigation as a helpful tool in the meningioma resection.
    Neurosurgical review, 2016, Volume: 39, Issue:3

    Topics: Adult; Aged; Aminolevulinic Acid; Female; Fluorescence; Humans; Male; Meningeal Neoplasms; Meningiom

2016
Blue Light Cystoscopy Should be Used Routinely for Bladder Cancer Detection: Pro.
    The Journal of urology, 2016, Volume: 195, Issue:6

    Topics: Aminolevulinic Acid; Cystectomy; Cystoscopy; Fluorescence; Humans; Neoplasm Recurrence, Local; Urina

2016
Long-term follow-up of patients with basal cell carcinoma after successful treatment with intralesional photodynamic therapy.
    Journal of the American Academy of Dermatology, 2016, Volume: 75, Issue:6

    Topics: Aminolevulinic Acid; Carcinoma, Basal Cell; Disease-Free Survival; Follow-Up Studies; Humans; Inject

2016
Treatment of Sweat gland carcinoma with Topical Aminolevulinic Acid Photodynamic therapy: An effective treatment method to improve surgical outcomes.
    Photodiagnosis and photodynamic therapy, 2017, Volume: 17

    Topics: Aminolevulinic Acid; Foot; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Photochemotherapy;

2017
Methyl-aminolevulinate photodynamic therapy for the treatment of actinic keratoses and non-melanoma skin cancers: a retrospective analysis of response in 462 patients.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2009, Volume: 144, Issue:3

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Carcinoma, Squ

2009
Improved detection and reduced early recurrence of non-muscle-invasive bladder cancer using hexaminolaevulinate fluorescence cystoscopy: results of a multicentre prospective randomized study (PC B305).
    BJU international, 2009, Volume: 104, Issue:7

    Topics: Aminolevulinic Acid; Carcinoma in Situ; Clinical Trials, Phase III as Topic; Cystoscopy; Humans; Mic

2009
Blue-sky thinking about blue-light cystoscopy.
    BJU international, 2009, Volume: 104, Issue:7

    Topics: Aminolevulinic Acid; Cystoscopy; Humans; Microscopy, Fluorescence; Neoplasm Recurrence, Local; Photo

2009
Methylaminolaevulinate photodynamic therapy in patients with multiple basal cell carcinomas in the setting of Gorlin-Goltz syndrome or after radiotherapy.
    Dermatology (Basel, Switzerland), 2009, Volume: 219, Issue:2

    Topics: Adult; Aged; Aminolevulinic Acid; Basal Cell Nevus Syndrome; Cohort Studies; Combined Modality Thera

2009
Hexaminolevulinate is equal to 5-aminolevulinic acid concerning residual tumor and recurrence rate following photodynamic diagnostic assisted transurethral resection of bladder tumors.
    Urology, 2009, Volume: 74, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carbon Radioisotopes; Cystectomy; Cystoscopy; F

2009
Hexylaminolaevulinate fluorescence cystoscopy in patients previously treated with intravesical bacille Calmette-Guérin.
    BJU international, 2010, Volume: 105, Issue:6

    Topics: Administration, Intravesical; Aged; Aged, 80 and over; Aminolevulinic Acid; Antineoplastic Agents; B

2010
Editorial comment.
    Urology, 2009, Volume: 74, Issue:6

    Topics: Aminolevulinic Acid; Carbon Radioisotopes; Cystectomy; Cystoscopy; Humans; Neoplasm Recurrence, Loca

2009
[Clinical experience with transurethral resection of bladder tumor (TUR-Bt) guided by photodynamic diagnosis (PDD)].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 2009, Volume: 100, Issue:7

    Topics: Administration, Intravesical; Aged; Aged, 80 and over; Aminolevulinic Acid; Disease-Free Survival; F

2009
New bladder cancer removal technique reduces recurrence.
    Mayo Clinic health letter (English ed.), 2010, Volume: 28, Issue:2

    Topics: Aminolevulinic Acid; Humans; Neoplasm Recurrence, Local; Urinary Bladder Neoplasms

2010
Intraoperative 5-aminolevulinic-acid-induced fluorescence in meningiomas.
    Acta neurochirurgica, 2010, Volume: 152, Issue:10

    Topics: Adult; Aged; Aminolevulinic Acid; Female; Fluorescence; Humans; Male; Meningeal Neoplasms; Meningiom

2010
Photodynamic diagnosis in patients with T1G3 bladder cancer: influence on recurrence rate.
    World journal of urology, 2010, Volume: 28, Issue:4

    Topics: Aged; Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Female; Follow-Up Studies; Humans; Kaplan-

2010
Confocal microscopy for the histological fluorescence pattern of a recurrent atypical meningioma: case report.
    Neurosurgery, 2011, Volume: 68, Issue:6

    Topics: Aminolevulinic Acid; Diagnostic Imaging; Female; Fluorescent Antibody Technique; Humans; Meningeal N

2011
Tumor thickness predicts long-term complete response of facial basal cell carcinomas in Asian skin types iv/v treated with methyl aminolaevulinate photodynamic therapy.
    Photomedicine and laser surgery, 2011, Volume: 29, Issue:7

    Topics: Aminolevulinic Acid; Biopsy; Carcinoma, Basal Cell; Chi-Square Distribution; China; Facial Neoplasms

2011
Evaluation of recurrence after photodynamic therapy with topical methylaminolaevulinate for 157 basal cell carcinomas in 90 patients.
    Acta dermato-venereologica, 2012, Volume: 92, Issue:2

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Female; Hum

2012
High and sustained efficacy after two sessions of topical 5-aminolaevulinic acid photodynamic therapy for basal cell carcinoma: a prospective, clinical and histological 10-year follow-up study.
    The British journal of dermatology, 2012, Volume: 166, Issue:6

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cel

2012
Facial extensive recurrent basal cell carcinoma: successful treatment with photodynamic therapy and imiquimod 5% cream.
    International journal of dermatology, 2012, Volume: 51, Issue:4

    Topics: Aged, 80 and over; Aminolevulinic Acid; Aminoquinolines; Antineoplastic Agents; Carcinoma, Basal Cel

2012
Editorial comment.
    The Journal of urology, 2012, Volume: 188, Issue:1

    Topics: Aminolevulinic Acid; Cystoscopy; Female; Humans; Male; Neoplasm Recurrence, Local; Neoplasm Staging;

2012
Cost-effectiveness of fluorescent cystoscopy for noninvasive papillary tumors: con.
    The Journal of urology, 2012, Volume: 187, Issue:5

    Topics: Aminolevulinic Acid; Carbon Radioisotopes; Carcinoma, Papillary; Cost-Benefit Analysis; Cystoscopy;

2012
Fluorescence-guided operation in recurrent glioblastoma multiforme treated with bevacizumab-fluorescence of the noncontrast enhancing tumor tissue?
    Journal of neurological surgery. Part A, Central European neurosurgery, 2012, Volume: 73, Issue:6

    Topics: Adult; Aminolevulinic Acid; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab;

2012
Editorial comment.
    Urology, 2012, Volume: 80, Issue:2

    Topics: Aminolevulinic Acid; Cystectomy; Female; Humans; Light; Male; Neoplasm Recurrence, Local; Radionucli

2012
Reflectance confocal microscopy allows in vivo real-time noninvasive assessment of the outcome of methyl aminolaevulinate photodynamic therapy of basal cell carcinoma.
    The British journal of dermatology, 2013, Volume: 168, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Dermoscopy; Female; Foll

2013
Daylight-mediated photodynamic therapy of basal cell carcinomas - an explorative study.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2014, Volume: 28, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Back; Carcinoma, Basal Cell; Facial Neoplasms;

2014
Do patients profit from 5-aminolevulinic acid-induced fluorescence diagnosis in transurethral resection of bladder carcinoma?
    Urology, 2002, Volume: 60, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma in Situ; Fluorescence; Humans

2002
Ultraviolet-excited (308 nm) autofluorescence for bladder cancer detection.
    Urology, 2002, Volume: 60, Issue:6

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Transitional Cell; Cystoscopy; False Positi

2002
Photodynamic therapy with intravesical instillation of 5-aminolevulinic acid for patients with recurrent superficial bladder cancer: a single-center study.
    Urology, 2003, Volume: 61, Issue:2

    Topics: Administration, Intravesical; Adult; Aged; Aminolevulinic Acid; Female; Follow-Up Studies; Humans; I

2003
Repetitive 5-aminolevulinic acid-mediated photodynamic therapy on human glioma spheroids.
    Journal of neuro-oncology, 2003, Volume: 62, Issue:3

    Topics: Aminolevulinic Acid; Brain Neoplasms; Combined Modality Therapy; Glioblastoma; Humans; Microscopy, F

2003
Topical 5-aminolaevulinic acid photodynamic therapy for cutaneous lesions: outcome and comparison of light sources.
    Photodermatology, photoimmunology & photomedicine, 2003, Volume: 19, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; England

2003
Recurrence rate of basal cell carcinoma after topical aminolevulinic acid-based photodynamic therapy.
    Acta dermatovenerologica Croatica : ADC, 2004, Volume: 12, Issue:3

    Topics: Administration, Topical; Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Female; Humans; Male; Neo

2004
5-Aminolevulinic acid-based photodynamic therapy for the treatment of two patients with extramammary Paget's disease.
    The Journal of dermatology, 2005, Volume: 32, Issue:2

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Genital Neoplasms, Female; Genital Neoplasms,

2005
Evaluation of different treatment modalities for vulvar intraepithelial neoplasia (VIN): CO(2) laser vaporization, photodynamic therapy, excision and vulvectomy.
    Gynecologic oncology, 2006, Volume: 100, Issue:2

    Topics: Adult; Aminolevulinic Acid; Carcinoma in Situ; Female; Gynecologic Surgical Procedures; Humans; Lase

2006
Clinical and research applications of photodynamic therapy in dermatology: experience of the Scottish PDT Centre.
    Lasers in surgery and medicine, 2006, Volume: 38, Issue:5

    Topics: Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Humans; Keratosis; Neoplasm Recurrence,

2006
Aminolevulinic acid 585 nm pulsed dye laser photodynamic treatment of laryngeal keratosis with atypia.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2007, Volume: 136, Issue:6

    Topics: Administration, Topical; Aged; Ambulatory Care; Aminolevulinic Acid; Biopsy; Cell Transformation, Ne

2007
Use of 5-aminolevulinic acid in fluorescence-guided resection of meningioma with high risk of recurrence. Case report.
    Journal of neurosurgery, 2007, Volume: 106, Issue:6

    Topics: Aged; Aminolevulinic Acid; Craniotomy; Female; Fluorescence; Humans; Magnetic Resonance Imaging; Men

2007
Interstitial photodynamic therapy of nonresectable malignant glioma recurrences using 5-aminolevulinic acid induced protoporphyrin IX.
    Lasers in surgery and medicine, 2007, Volume: 39, Issue:5

    Topics: Adult; Aged; Aminolevulinic Acid; Brain Neoplasms; Feasibility Studies; Glioma; Humans; Magnetic Res

2007
Preliminary results of intraoperative photodynamic therapy with 5-aminolevulinic acid in dogs with prostate carcinoma.
    Veterinary journal (London, England : 1997), 2008, Volume: 178, Issue:2

    Topics: Aminolevulinic Acid; Animals; Combined Modality Therapy; Dog Diseases; Dogs; Intraoperative Care; Ma

2008
Long-sustaining response in a patient with non-resectable, distant recurrence of glioblastoma multiforme treated by interstitial photodynamic therapy using 5-ALA: case report.
    Journal of neuro-oncology, 2008, Volume: 87, Issue:1

    Topics: Adult; Aminolevulinic Acid; Brain Neoplasms; Combined Modality Therapy; Female; Glioblastoma; Humans

2008
Thioredoxin upregulation by 5-aminolaevulinic acid-based photodynamic therapy in human skin squamous cell carcinoma cell line.
    Photodermatology, photoimmunology & photomedicine, 2008, Volume: 24, Issue:3

    Topics: Aminolevulinic Acid; Analysis of Variance; Blotting, Western; Carcinoma, Squamous Cell; Caspase 3; C

2008
Unilateral localized basaliomatosis: treatment with topical photodynamic therapy after application of 5-aminolevulinic acid.
    Dermatology (Basel, Switzerland), 1995, Volume: 190, Issue:3

    Topics: Administration, Cutaneous; Aged; Aminolevulinic Acid; Basal Cell Nevus Syndrome; Carcinoma, Basal Ce

1995
[Use of photodynamic laser therapy in gynecology].
    Gynakologisch-geburtshilfliche Rundschau, 1995, Volume: 35, Issue:2

    Topics: Adult; Aged; Aminolevulinic Acid; Female; Follow-Up Studies; Genital Neoplasms, Female; Genitalia, F

1995
Adjuvant intraoperative photodynamic therapy diminishes the rate of local recurrence in a rat mammary tumour model.
    British journal of cancer, 1995, Volume: 71, Issue:4

    Topics: Adenocarcinoma; Aminolevulinic Acid; Analysis of Variance; Animals; Chemotherapy, Adjuvant; Female;

1995
[Photodynamic diagnosis of urothelial neoplasms after intravesicular instillation of 5-aminolevulinic acid].
    Der Urologe. Ausg. A, 1994, Volume: 33, Issue:4

    Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma

1994
Early clinical experience with 5-aminolevulinic acid for the photodynamic therapy of superficial bladder cancer.
    British journal of urology, 1996, Volume: 77, Issue:5

    Topics: Administration, Intravesical; Adult; Aged; Aminolevulinic Acid; Female; Follow-Up Studies; Humans; M

1996
[The clinical value of fluorescence cystoscopy in the detection of superficial transitional epithelial cell carcinoma of the bladder].
    Annales d'urologie, 1997, Volume: 31, Issue:1

    Topics: Administration, Intravesical; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Carci

1997
[Fluorescence--endoscopy in carcinoma of the urinary bladder].
    Biomedizinische Technik. Biomedical engineering, 1998, Volume: 43 Suppl

    Topics: Aminolevulinic Acid; Cystoscopes; Humans; Neoplasm Recurrence, Local; Precancerous Conditions; Urina

1998
Clinical results of the transurethreal resection and evaluation of superficial bladder carcinomas by means of fluorescence diagnosis after intravesical instillation of 5-aminolevulinic acid.
    Journal of endourology, 1999, Volume: 13, Issue:2

    Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma

1999
Photodynamic therapy of feline superficial squamous cell carcinoma using topical 5-aminolaevulinic acid.
    The Journal of small animal practice, 2001, Volume: 42, Issue:4

    Topics: Administration, Topical; Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Cat Diseases; Cats;

2001
Clinical experience with 5-aminolevulinic acid and photodynamic therapy for refractory superficial bladder cancer.
    The Journal of urology, 2001, Volume: 165, Issue:6 Pt 1

    Topics: Adult; Aged; Aminolevulinic Acid; Carcinoma, Transitional Cell; Female; Humans; Male; Middle Aged; N

2001
A follow-up study of recurrence and cosmesis in completely responding superficial and nodular basal cell carcinomas treated with methyl 5-aminolaevulinate-based photodynamic therapy alone and with prior curettage.
    The British journal of dermatology, 2001, Volume: 145, Issue:3

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Combined Modality Therapy; Esth

2001
Quantification of 5-aminolevulinic acid induced fluorescence improves the specificity of bladder cancer detection.
    The Journal of urology, 2001, Volume: 166, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Transitional Cell; Cystoscopy; Femal

2001
Photodynamic therapy of premalignant lesions and local recurrence of laryngeal and hypopharyngeal cancers.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2001, Volume: 258, Issue:7

    Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Female; Humans; Hypopharyngeal Neoplasms; Laryngeal N

2001
Comparison of the bladder tumour antigen test with photodynamic diagnosis in patients with pathologically confirmed recurrent superficial urinary bladder tumours.
    BJU international, 2002, Volume: 89, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Antigens, Neoplasm; Biomarkers, Tumor; Cystosco

2002
[Fluorescent endoscopy superior to white light endoscopy. Detecting cancers of the urinary bladder earlier].
    MMW Fortschritte der Medizin, 2002, Mar-28, Volume: 144, Issue:13

    Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell; Cystoscopy; Fluorescence; Huma

2002
Aminolevulinic acid hydrochloride with photodynamic therapy: efficacy outcomes and recurrence 4 years after treatment.
    Cutis, 2002, Volume: 69, Issue:6 Suppl

    Topics: Administration, Cutaneous; Adult; Aged; Aminolevulinic Acid; Clinical Trials, Phase II as Topic; Fac

2002
5-Aminolevulinic Acid-Guided Surgery for Recurrent Supratentorial Pediatric Neoplasms.
    World neurosurgery, 2020, Volume: 141

    Topics: Aminolevulinic Acid; Brain Neoplasms; Child; Child, Preschool; Female; Fluorescent Dyes; Humans; Lev

2020