Page last updated: 2024-10-16

aminolevulinic acid and Lichen Sclerosus et Atrophicus

aminolevulinic acid has been researched along with Lichen Sclerosus et Atrophicus in 9 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Lichen Sclerosus et Atrophicus: A chronic inflammatory mucocutaneous disease usually affecting the female genitalia (VULVAR LICHEN SCLEROSUS) and BALANITIS XEROTICA OBLITERANS in males. It is also called white spot disease and Csillag's disease.

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's3 (33.33)29.6817
2010's3 (33.33)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Hao, J1
Liu, J1
Monfrecola, G1
Megna, M1
Rovati, C1
Arisi, M1
Rossi, M1
Calzavara-Pinton, I1
Fabbrocini, G1
Calzavara-Pinton, P1
Criscuolo, AA1
Schipani, C1
Cannizzaro, MV1
Messinese, S1
Chimenti, S1
Piccione, E1
Saraceno, R1
Olejek, A2
Gabriel, I1
Bilska-Janosik, A1
Kozak-Darmas, I2
Kawczyk-Krupka, A1
Passeron, T1
Lacour, JP1
Ortonne, JP1
Kellas-Sleczka, S1
Steplewska, K1
Biniszkiewicz, T1
Birkner, B1
Jarek, A1
Nowak, L1
Stencel-Gabriel, K1
Sieron, A1
Hillemanns, P1
Untch, M1
Pröve, F1
Baumgartner, R1
Hillemanns, M1
Korell, M1
Szeimies, RM1
Landthaler, M1
Karrer, S1
Lan, T1
Zou, Y1
Hamblin, MR1
Yin, R1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Vulvar Lichen Sclerosus: Therapeutic Comparison Between Clobetasol Propionate, Photodynamic Therapy and Low-Intensity Laser[NCT02416531]30 participants (Actual)Interventional2015-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for aminolevulinic acid and Lichen Sclerosus et Atrophicus

ArticleYear
A Critical Reappraisal of Off-Label Use of Photodynamic Therapy for the Treatment of Non-Neoplastic Skin Conditions.
    Dermatology (Basel, Switzerland), 2021, Volume: 237, Issue:2

    Topics: Acne Vulgaris; Aminolevulinic Acid; Cosmetic Techniques; Humans; Lichen Sclerosus et Atrophicus; Off

2021
Non-oncologic indications for ALA-PDT.
    The Journal of dermatological treatment, 2002, Volume: 13 Suppl 1

    Topics: Aminolevulinic Acid; Humans; Lichen Sclerosus et Atrophicus; Papillomavirus Infections; Photochemoth

2002

Trials

3 trials available for aminolevulinic acid and Lichen Sclerosus et Atrophicus

ArticleYear
ALA-Photodynamic treatment in Lichen sclerosus-clinical and immunological outcome focusing on the assesment of antinuclear antibodies.
    Photodiagnosis and photodynamic therapy, 2017, Volume: 18

    Topics: Aminolevulinic Acid; Antibodies, Antinuclear; Cytokines; Dose-Response Relationship, Drug; Dose-Resp

2017
Effectiveness of photodynamic therapy in the treatment of lichen sclerosus: cell changes in immunohistochemistry.
    Neuro endocrinology letters, 2009, Volume: 30, Issue:4

    Topics: Adult; Aged; Aminolevulinic Acid; Antigens, CD34; Biopsy; CD3 Complex; Dermis; Epidermis; Female; Hu

2009
Photodynamic therapy of vulvar lichen sclerosus with 5-aminolevulinic acid.
    Obstetrics and gynecology, 1999, Volume: 93, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Lichen Sclerosus et Atrophicus;

1999

Other Studies

4 other studies available for aminolevulinic acid and Lichen Sclerosus et Atrophicus

ArticleYear
Feasibility of 5-aminolevulinic acid mediated photodynamic therapy for male genital lichen sclerosus.
    Photodiagnosis and photodynamic therapy, 2020, Volume: 29

    Topics: Adult; Aminolevulinic Acid; Genital Diseases, Male; Humans; Lichen Sclerosus et Atrophicus; Male; Ph

2020
New therapeutic approaches in the treatment of anogenital lichen sclerosus: does photodynamic therapy represent a novel option?
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2017, Volume: 152, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Aminolevulinic Acid; Anus Diseases; Calcineurin Inhibito

2017
Comparative treatment of extragenital lichen sclerosus with methylaminolevulinic Acid pulsed dye laser-mediated photodynamic therapy or pulsed dye laser alone.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2009, Volume: 35, Issue:5

    Topics: Abdominal Wall; Aminolevulinic Acid; Female; Follow-Up Studies; Humans; Laser Therapy; Lasers, Dye;

2009
5-Aminolevulinic acid photodynamic therapy in refractory vulvar lichen sclerosus et atrophicus: Series of ten cases.
    Photodiagnosis and photodynamic therapy, 2018, Volume: 21

    Topics: Adult; Aminolevulinic Acid; Female; Humans; Levulinic Acids; Lichen Sclerosus et Atrophicus; Middle

2018