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aminolevulinic acid and Leishmaniasis, Cutaneous

aminolevulinic acid has been researched along with Leishmaniasis, Cutaneous in 18 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Leishmaniasis, Cutaneous: An endemic disease that is characterized by the development of single or multiple localized lesions on exposed areas of skin that typically ulcerate. The disease has been divided into Old and New World forms. Old World leishmaniasis is separated into three distinct types according to epidemiology and clinical manifestations and is caused by species of the L. tropica and L. aethiopica complexes as well as by species of the L. major genus. New World leishmaniasis, also called American leishmaniasis, occurs in South and Central America and is caused by species of the L. mexicana or L. braziliensis complexes.

Research Excerpts

ExcerptRelevanceReference
"Cutaneous leishmaniasis is one of the most common travel dermatoses in Germany, which can be acquired not only in Africa, Asia or the American continent, but also in southern European countries."1.72[Successful treatment of Old World cutaneous leishmaniasis with red or green light photodynamic therapy]. ( Balakirski, G; Burmann, SN; Hofmann, SC; Kreuter, A; Lehmann, P; Oellig, F; Paschos, A, 2022)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (38.89)29.6817
2010's6 (33.33)24.3611
2020's5 (27.78)2.80

Authors

AuthorsStudies
Burmann, SN1
Oellig, F1
Paschos, A1
Hofmann, SC1
Lehmann, P1
Kreuter, A1
Balakirski, G1
Liu, L1
He, Y1
Chang, J1
Khan, K1
Khan, AU1
Khan, A1
Khan, M1
Ahmad, I1
Sharma, R1
Viana, SM1
Ng, DKP1
Kolli, BK1
Chang, KP1
de Oliveira, CI1
Hobelsberger, S1
Krauß, MP1
Bogdan, C1
Aschoff, R1
Slape, DR1
Kim, EN1
Weller, P1
Gupta, M1
Johansen, MB1
Jemec, GBE1
Fabricius, S1
Souza, DM1
Alves, PM1
Silva, ML1
Paulino, TP1
Coraspe, HO1
Mendonça, MM1
Ribeiro, BM1
da Silva, MV1
Rodrigues Júnior, V1
Rodrigues, DB1
van der Snoek, EM1
Robinson, DJ1
van Hellemond, JJ1
Neumann, HA1
Kluger, N1
Girard, C1
Debu, A1
Guillot, B1
Evangelou, G1
Krasagakis, K1
Giannikaki, E1
Kruger-Krasagakis, S1
Tosca, A1
Lee, Y1
Baron, ED1
Enk, CD2
Fritsch, C2
Jonas, F1
Nasereddin, A1
Ingber, A1
Jaffe, CL1
Ruzicka, T3
Gardlo, K2
Horska, Z1
Rauch, L1
Megahed, M1
Hanneken, S1
Neumann, NJ1
Kosaka, S2
Akilov, OE2
O'Riordan, K2
Hasan, T2
Ghaffarifar, F1
Jorjani, O1
Mirshams, M1
Miranbaygi, MH1
Hosseini, ZK1

Reviews

3 reviews available for aminolevulinic acid and Leishmaniasis, Cutaneous

ArticleYear
Efficacy of photodynamic therapy in cutaneous leishmaniasis: A systematic review.
    Photodiagnosis and photodynamic therapy, 2023, Volume: 43

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Child; Child, Preschool; Humans; In

2023
A review of photodynamic therapy in cutaneous leishmaniasis.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2008, Volume: 22, Issue:8

    Topics: Aminolevulinic Acid; Humans; Leishmaniasis, Cutaneous; Photochemotherapy; Photosensitizing Agents; P

2008
Photodynamic therapy: current evidence and applications in dermatology.
    Seminars in cutaneous medicine and surgery, 2011, Volume: 30, Issue:4

    Topics: Acne Vulgaris; Aminolevulinic Acid; Bowen's Disease; Candidiasis; Carcinoma, Basal Cell; Humans; Ker

2011

Trials

2 trials available for aminolevulinic acid and Leishmaniasis, Cutaneous

ArticleYear
Fractionated illumination improves the treatment outcomes of photodynamic therapy for high grade cutaneous leishmaniasis.
    Photodiagnosis and photodynamic therapy, 2020, Volume: 29

    Topics: Aminolevulinic Acid; Female; Humans; Leishmaniasis, Cutaneous; Male; Pain Measurement; Pakistan; Pho

2020
Photodynamic therapy as a new treatment of cutaneous leishmaniasis.
    Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit, 2006, Volume: 12, Issue:6

    Topics: Aminolevulinic Acid; Drug Administration Schedule; Drug Monitoring; Humans; Hyperpigmentation; Infla

2006

Other Studies

13 other studies available for aminolevulinic acid and Leishmaniasis, Cutaneous

ArticleYear
[Successful treatment of Old World cutaneous leishmaniasis with red or green light photodynamic therapy].
    Dermatologie (Heidelberg, Germany), 2022, Volume: 73, Issue:12

    Topics: Aminolevulinic Acid; Humans; Leishmaniasis, Cutaneous; Photochemotherapy; Photosensitizing Agents

2022
Photodynamic inactivation of Leishmania braziliensis doubly sensitized with uroporphyrin and diamino-phthalocyanine activates effector functions of macrophages in vitro.
    Scientific reports, 2020, 10-13, Volume: 10, Issue:1

    Topics: Aminolevulinic Acid; Animals; Animals, Genetically Modified; Female; Humans; Immunity, Innate; In Vi

2020
[Successful treatment of cutaneous leishmaniasis with simulated daylight photodynamic therapy].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2022, Volume: 73, Issue:5

    Topics: Aminolevulinic Acid; Child, Preschool; Humans; Leishmania tropica; Leishmaniasis, Cutaneous; Male; P

2022
Leishmania tropica successfully treated with photodynamic therapy.
    The Australasian journal of dermatology, 2019, Volume: 60, Issue:1

    Topics: Adult; Aminolevulinic Acid; Facial Dermatoses; Humans; Leishmania tropica; Leishmaniasis, Cutaneous;

2019
Effective treatment with photodynamic therapy of cutaneous leishmaniasis: A case report.
    Dermatologic therapy, 2019, Volume: 32, Issue:5

    Topics: Adolescent; Aminolevulinic Acid; Follow-Up Studies; Humans; Leishmaniasis, Cutaneous; Male; Photoche

2019
5-ALA-mediated photodynamic therapy reduces the parasite load in mice infected with Leishmania braziliensis.
    Parasite immunology, 2017, Volume: 39, Issue:3

    Topics: Aminolevulinic Acid; Animals; Cytokines; Interferon-gamma; Leishmania braziliensis; Leishmaniasis, C

2017
Efficacy of photodynamic therapy in cutaneous leishmaniasis: a "hidden" local heat effect?
    Medical hypotheses, 2010, Volume: 75, Issue:6

    Topics: Aminolevulinic Acid; Hot Temperature; Humans; Leishmaniasis, Cutaneous; Light; Photochemotherapy

2010
Successful treatment of cutaneous leishmaniasis with intralesional aminolevulinic acid photodynamic therapy.
    Photodermatology, photoimmunology & photomedicine, 2011, Volume: 27, Issue:5

    Topics: Administration, Topical; Aged; Aminolevulinic Acid; Humans; Leishmaniasis, Cutaneous; Male; Photoche

2011
Treatment of cutaneous leishmaniasis with photodynamic therapy.
    Archives of dermatology, 2003, Volume: 139, Issue:4

    Topics: Adult; Aminolevulinic Acid; Female; Humans; Leishmaniasis, Cutaneous; Male; Middle Aged; Photochemot

2003
Treatment of cutaneous leishmaniasis by photodynamic therapy.
    Journal of the American Academy of Dermatology, 2003, Volume: 48, Issue:6

    Topics: Adult; Amebicides; Aminolevulinic Acid; Humans; Leishmaniasis, Cutaneous; Male; Ointments; Paromomyc

2003
[Photodynamic therapy of cutaneous leishmaniasis. A promising new therapeutic modality].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2004, Volume: 55, Issue:4

    Topics: Adult; Aminolevulinic Acid; Diagnosis, Differential; Humans; Leishmaniasis, Cutaneous; Male; Photoch

2004
A mechanistic study of delta-aminolevulinic acid-based photodynamic therapy for cutaneous leishmaniasis.
    The Journal of investigative dermatology, 2007, Volume: 127, Issue:6

    Topics: Aminolevulinic Acid; Animals; Cell Line, Transformed; Leishmania major; Leishmaniasis, Cutaneous; Ma

2007
Parasiticidal effect of delta-aminolevulinic acid-based photodynamic therapy for cutaneous leishmaniasis is indirect and mediated through the killing of the host cells.
    Experimental dermatology, 2007, Volume: 16, Issue:8

    Topics: Aminolevulinic Acid; Animals; Cell Line, Transformed; Disease Models, Animal; Ear, External; Interle

2007