Page last updated: 2024-10-16

aminolevulinic acid and Leg Ulcer

aminolevulinic acid has been researched along with Leg Ulcer in 5 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Leg Ulcer: Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Lin, MH1
Lee, JY1
Pan, SC1
Wong, TW1
Borgia, F1
Vaccaro, M1
Cantavenera, LG1
Aragona, E1
Cannavò, SP1
Lei, X1
Liu, B1
Huang, Z1
Wu, J1
Strauss, RM1
Ogden, S1
Sheehan-Dare, RA1
Goulden, V1
Clayton, TH1
Harrison, PV1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Safety of Methylene Blue -Mediated Photodynamic Therapy for Diabetic Lower Limb Ulcer : a Randomized Controlled Study[NCT03222544]60 participants (Anticipated)Interventional2019-04-29Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for aminolevulinic acid and Leg Ulcer

ArticleYear
Ulcerative necrobiosis lipoidica successfully treated with photodynamic therapy: case report and literature review.
    Photodiagnosis and photodynamic therapy, 2014, Volume: 11, Issue:4

    Topics: Adult; Aminolevulinic Acid; Female; Humans; Leg Ulcer; Necrobiosis Lipoidica; Photochemotherapy; Pho

2014

Trials

1 trial available for aminolevulinic acid and Leg Ulcer

ArticleYear
A clinical study of photodynamic therapy for chronic skin ulcers in lower limbs infected with Pseudomonas aeruginosa.
    Archives of dermatological research, 2015, Volume: 307, Issue:1

    Topics: Adult; Aged; Aminolevulinic Acid; Bacterial Load; China; Chronic Disease; Colony Count, Microbial; F

2015

Other Studies

3 other studies available for aminolevulinic acid and Leg Ulcer

ArticleYear
Enhancing wound healing in recalcitrant leg ulcers with aminolevulinic acid-mediated antimicrobial photodynamic therapy.
    Photodiagnosis and photodynamic therapy, 2021, Volume: 33

    Topics: Aminolevulinic Acid; Anti-Infective Agents; Humans; Leg Ulcer; Photochemotherapy; Photosensitizing A

2021
Leg ulceration after aminolaevulinic acid photodynamic therapy in a patient with peripheral vascular disease.
    Dermatology (Basel, Switzerland), 2003, Volume: 207, Issue:1

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Follow-Up Studies; Humans; Leg Ulcer; Peripher

2003
Photodynamic therapy for infected leg ulcers.
    The British journal of dermatology, 2007, Volume: 156, Issue:2

    Topics: Aged; Aminolevulinic Acid; Chronic Disease; Female; Humans; Leg Ulcer; Methicillin Resistance; Photo

2007