aminolevulinic acid has been researched along with Keratoderma Blennorrhagicum in 115 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Photodynamic therapy using topical methyl 5-aminolevulinate (MAL) is a new treatment modality for basal cell carcinoma (BCC) and actinic keratosis (AK)." | 9.12 | Porphyrin formation in actinic keratosis and basal cell carcinoma after topical application of methyl 5-aminolevulinate. ( Angell-Petersen, E; Giercksky, KE; Moan, J; Peng, Q; Soler, AM; Sørensen, R; Warloe, T, 2006) |
| "Topical 5-aminolevulinic acid-based photodynamic therapy (ALA-PDT) has been established in recent years as an effective treatment for disseminated actinic keratosis (AK)." | 9.11 | Efficacy of 3 different light doses in the treatment of actinic keratosis with 5-aminolevulinic acid photodynamic therapy: a randomized, observer-blinded, intrapatient, comparison study. ( Blecha-Thalhammer, U; Hönigsmann, H; Kittler, H; Radakovic-Fijan, S; Tanew, A, 2005) |
| "Since its FDA approval in 1999, photodynamic therapy (PDT) with topical 5-aminolevulinic acid has become an increasingly popular modality for the treatment of actinic keratosis (AKs)." | 7.73 | Development of a keratoacanthoma after topical photodynamic therapy with 5-aminolevulinic acid. ( Goldman, MP; Maydan, E; Nootheti, PK, 2006) |
| "We report the case of a 82-year-old man who, after multiple treatments with aminolevulinic acid photodynamic therapy for solar keratoses and superficial squamous cell carcinomas, developed malignant melanoma at the exposed site on the scalp." | 7.69 | Development of malignant melanoma after repeated topical photodynamic therapy with 5-aminolevulinic acid at the exposed site. ( Fink-Puches, R; Kerl, H; Reimann-Weber, A; Wolf, P, 1997) |
| "Although PDT is a well-tolerated treatment, pain is the most severe side effect." | 6.72 | Photodynamic therapy induces less pain in patients treated with methyl aminolevulinate compared to aminolevulinic acid. ( Hein, R; Kasche, A; Luderschmidt, S; Ring, J, 2006) |
| "Pain was assessed pre-illumination, during, and immediately after illumination, using a numeric rating scale." | 6.72 | Morphine gel 0.3% does not relieve pain during topical photodynamic therapy: a randomized, double-blind, placebo-controlled study. ( Haedersdal, M; Philipsen, PA; Skiveren, J; Wiegell, SR; Wulf, HC, 2006) |
| "Photodynamic therapy using topical methyl 5-aminolevulinate (MAL) is a new treatment modality for basal cell carcinoma (BCC) and actinic keratosis (AK)." | 5.12 | Porphyrin formation in actinic keratosis and basal cell carcinoma after topical application of methyl 5-aminolevulinate. ( Angell-Petersen, E; Giercksky, KE; Moan, J; Peng, Q; Soler, AM; Sørensen, R; Warloe, T, 2006) |
| "Topical 5-aminolevulinic acid (ALA) and various light sources have been used to treat actinic keratoses and acne." | 5.12 | Efficacy of microdermabrasion preceding ALA application in reducing the incubation time of ALA in laser PDT. ( Frew, KE; George, D; Katz, BE; Maiwald, DC; Truong, S, 2007) |
| "Topical 5-aminolevulinic acid-based photodynamic therapy (ALA-PDT) has been established in recent years as an effective treatment for disseminated actinic keratosis (AK)." | 5.11 | Efficacy of 3 different light doses in the treatment of actinic keratosis with 5-aminolevulinic acid photodynamic therapy: a randomized, observer-blinded, intrapatient, comparison study. ( Blecha-Thalhammer, U; Hönigsmann, H; Kittler, H; Radakovic-Fijan, S; Tanew, A, 2005) |
| "Methyl aminolevulinate (MAL), an ester of aminolevulinic acid, has been used effectively as a topical photosensitizing agent in the photodynamic therapy (PDT) of epidermal lesions such as actinic keratosis (AK) and basal cell carcinoma (BCC)." | 4.82 | Topical methyl aminolevulinate. ( Perry, CM; Scott, LJ; Siddiqui, MA, 2004) |
| "A literature review and results of new clinical trials with regards to photorejuvenation and acne vulgaris treatments with 5-aminolevulinic acid photodynamic therapy are presented." | 4.82 | 5-aminolevulinic acid photodynamic therapy: where we have been and where we are going. ( Gold, MH; Goldman, MP, 2004) |
| "Short-contact, full-face 5-aminolevulinic acid photodynamic therapy treatments with a variety of lasers and light sources have shown to be successful in treating all facets of photorejuvenation and the associated actinic keratoses as well as disorders of sebaceous glands, including acne vulgaris." | 4.82 | 5-aminolevulinic acid photodynamic therapy: where we have been and where we are going. ( Gold, MH; Goldman, MP, 2004) |
| "Twelve actinic keratosis lesions in seven patients were treated with 5-aminolevulinic acid-PDT using intense pulsed light as a light source." | 3.73 | Topical photodynamic therapy using intense pulsed light for treatment of actinic keratosis: clinical and histopathologic evaluation. ( Cho, KH; Kim, HS; Kwon, OS; Moon, SE; Yoo, JY, 2005) |
| "To evaluate a novel light patch formulated for blue light delivery and topical activation of gamma-aminolevulinic acid (ALA) during photodynamic therapy for the treatment of actinic keratosis (AK)." | 3.73 | Light patch: preliminary report of a novel form of blue light delivery for the treatment of actinic keratosis. ( Coles, C; Counters, J; Selim, M; Zelickson, B, 2005) |
| "Since its FDA approval in 1999, photodynamic therapy (PDT) with topical 5-aminolevulinic acid has become an increasingly popular modality for the treatment of actinic keratosis (AKs)." | 3.73 | Development of a keratoacanthoma after topical photodynamic therapy with 5-aminolevulinic acid. ( Goldman, MP; Maydan, E; Nootheti, PK, 2006) |
| "The safety and efficacy of treating individuals who presented with multiple actinic keratosis (AK) lesions with 5-aminolevulinic acid (ALA) in combination with photodynamic therapy (PDT) were documented in a phase III trial." | 3.71 | Aminolevulinic acid hydrochloride with photodynamic therapy: efficacy outcomes and recurrence 4 years after treatment. ( Fowler, JF; Zax, RH, 2002) |
| "The safety and efficacy of treating individuals who presented with multiple actinic keratosis (AK) lesions with 5-aminolevulinic acid (ALA) in combination with photodynamic therapy (PDT) were documented in a phase III trial." | 3.71 | The evolving role of aminolevulinic acid hydrochloride with photodynamic therapy in photoaging. ( Gold, MH, 2002) |
| "We report the case of a 82-year-old man who, after multiple treatments with aminolevulinic acid photodynamic therapy for solar keratoses and superficial squamous cell carcinomas, developed malignant melanoma at the exposed site on the scalp." | 3.69 | Development of malignant melanoma after repeated topical photodynamic therapy with 5-aminolevulinic acid at the exposed site. ( Fink-Puches, R; Kerl, H; Reimann-Weber, A; Wolf, P, 1997) |
| "Pain was assessed by the patient using a visual analog scale directly after treatment." | 2.73 | Effect of subcutaneous infiltration anesthesia on pain in photodynamic therapy: a controlled open pilot trial. ( Berking, C; Borelli, C; Degitz, K; Herzinger, T; Kunte, C; Merk, K; Plewig, G, 2007) |
| "Pain was assessed using a visual analogue scale at 3, 6, 12 and 16 min." | 2.73 | Randomized, double-blind, prospective study to compare topical 5-aminolaevulinic acid methylester with topical 5-aminolaevulinic acid photodynamic therapy for extensive scalp actinic keratosis. ( Collins, P; Moloney, FJ, 2007) |
| "Although PDT is a well-tolerated treatment, pain is the most severe side effect." | 2.72 | Photodynamic therapy induces less pain in patients treated with methyl aminolevulinate compared to aminolevulinic acid. ( Hein, R; Kasche, A; Luderschmidt, S; Ring, J, 2006) |
| "Pain was assessed pre-illumination, during, and immediately after illumination, using a numeric rating scale." | 2.72 | Morphine gel 0.3% does not relieve pain during topical photodynamic therapy: a randomized, double-blind, placebo-controlled study. ( Haedersdal, M; Philipsen, PA; Skiveren, J; Wiegell, SR; Wulf, HC, 2006) |
| "The response rate of Bowen's disease to MAL-PDT is also at least equivalent to cryotherapy and 5-fluorouracil, again with superior cosmesis." | 2.44 | Methyl aminolevulinate: actinic keratoses and Bowen's disease. ( Morton, CA, 2007) |
| "Aminolevulinic acid (ALA) has been shown to be the drug with most experimental and clinical use in the past." | 2.43 | Fluorescence diagnosis and photodynamic therapy in dermatology from experimental state to clinic standard methods. ( Fritsch, C; Ruzicka, T, 2006) |
| "Actinic keratosis is currently believed to be an early stage in the evolution of squamous cell carcinoma." | 2.42 | Topical and light-based treatments for actinic keratoses. ( Alam, M; Goldberg, LH; Silapunt, S, 2003) |
| "As the first stage of squamous cell carcinoma, actinic keratosis is worthy of prompt evaluation and active treatment." | 2.42 | Topical and light-based treatments for actinic keratoses. ( Alam, M; Goldberg, LH; Silapunt, S, 2003) |
| " The studies investigated the influence of patch application duration on PPIX-specific fluorescence and the pharmacokinetic properties of the 5-ALA patch." | 1.35 | Fluorescence characteristics and pharmacokinetic properties of a novel self-adhesive 5-ALA patch for photodynamic therapy of actinic keratoses. ( Ackermann, G; Birkel, M; Breuer, M; Ebeling, A; Fauteck, JD; Moor, AC; Ortland, C, 2008) |
| "The concept of skin cancer prevention with photodynamic therapy has evolved over the past few years to include large surface application of aminolevulinic acid or methyl aminolevulinate followed by light exposure to prevent the development of new lesions." | 1.34 | Chemopreventative thoughts for photodynamic therapy. ( Bissonnette, R, 2007) |
| "Aminolevulinic acid (ALA) has demonstrated highest efficacy in topical PDT, and has become the most clinically useful." | 1.31 | Aminolevulinic acid (Levulan) in photodynamic therapy of actinic keratoses. ( Fritsch, C; Lang, K; Ruzicka, T; Schulte, KW, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (10.43) | 18.2507 |
| 2000's | 100 (86.96) | 29.6817 |
| 2010's | 3 (2.61) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Braathen, LR | 2 |
| Muñoz-Martínez, R | 1 |
| Santamarina-Albertos, A | 1 |
| Sanz-Muñoz, C | 1 |
| Miranda-Romero, A | 1 |
| Chopra, S | 1 |
| Downs, A | 1 |
| Perris, R | 1 |
| Toll, A | 1 |
| Parera, ME | 1 |
| Vélez, M | 1 |
| Pujol, RM | 1 |
| Wennberg, AM | 5 |
| Stenquist, B | 2 |
| Stockfleth, E | 1 |
| Keohane, S | 2 |
| Lear, JT | 1 |
| Jemec, G | 1 |
| Mork, C | 1 |
| Christensen, E | 1 |
| Kapp, A | 1 |
| Solvsten, H | 1 |
| Talme, T | 1 |
| Berne, B | 2 |
| Forschner, T | 1 |
| Pariser, D | 2 |
| Loss, R | 1 |
| Jarratt, M | 1 |
| Abramovits, W | 1 |
| Spencer, J | 1 |
| Geronemus, R | 1 |
| Bailin, P | 1 |
| Bruce, S | 1 |
| McLoone, N | 1 |
| Donnelly, RF | 1 |
| Walsh, M | 1 |
| Dolan, OM | 1 |
| McLoone, S | 1 |
| McKenna, K | 2 |
| McCarron, PA | 1 |
| Gerritsen, MJ | 2 |
| Smits, T | 2 |
| Kleinpenning, MM | 1 |
| van de Kerkhof, PC | 2 |
| van Erp, PE | 2 |
| Guarneri, C | 1 |
| Vaccaro, M | 1 |
| Szeimies, RM | 7 |
| Karrer, S | 4 |
| Radakovic-Fijan, S | 2 |
| Tanew, A | 2 |
| Calzavara-Pinton, PG | 1 |
| Zane, C | 2 |
| Sidoroff, A | 1 |
| Hempel, M | 1 |
| Ulrich, J | 1 |
| Proebstle, T | 1 |
| Meffert, H | 1 |
| Mulder, M | 1 |
| Salomon, D | 1 |
| Dittmar, HC | 1 |
| Bauer, JW | 1 |
| Kernland, K | 1 |
| Braathen, L | 1 |
| Ruiz-Rodriguez, R | 1 |
| Sanz-Sánchez, T | 1 |
| Córdoba, S | 1 |
| Pariser, DM | 3 |
| Lowe, NJ | 3 |
| Stewart, DM | 1 |
| Jarratt, MT | 1 |
| Lucky, AW | 1 |
| Pariser, RJ | 1 |
| Yamauchi, PS | 2 |
| Epstein, E | 1 |
| Freeman, M | 1 |
| Vinciullo, C | 1 |
| Francis, D | 1 |
| Spelman, L | 2 |
| Nguyen, R | 1 |
| Fergin, P | 2 |
| Thai, KE | 1 |
| Murrell, D | 1 |
| Weightman, W | 2 |
| Anderson, C | 1 |
| Reid, C | 1 |
| Watson, A | 1 |
| Foley, P | 3 |
| Zeitouni, NC | 1 |
| Oseroff, AR | 1 |
| Shieh, S | 1 |
| Goldman, M | 1 |
| Atkin, D | 2 |
| Touma, DJ | 1 |
| Gilchrest, BA | 2 |
| Clark, C | 1 |
| Bryden, A | 1 |
| Dawe, R | 1 |
| Moseley, H | 3 |
| Ferguson, J | 2 |
| Ibbotson, SH | 1 |
| Marcus, L | 1 |
| Silapunt, S | 1 |
| Goldberg, LH | 1 |
| Alam, M | 1 |
| Smith, S | 1 |
| Piacquadio, D | 1 |
| Morhenn, V | 1 |
| Fitzpatrick, R | 1 |
| Dragieva, G | 2 |
| Hafner, J | 2 |
| Dummer, R | 2 |
| Schmid-Grendelmeier, P | 1 |
| Roos, M | 1 |
| Prinz, BM | 2 |
| Burg, G | 2 |
| Binswanger, U | 2 |
| Kempf, W | 2 |
| Touma, D | 1 |
| Yaar, M | 1 |
| Whitehead, S | 1 |
| Konnikov, N | 1 |
| Piacquadio, DJ | 1 |
| Chen, DM | 1 |
| Farber, HF | 1 |
| Fowler, JF | 2 |
| Glazer, SD | 2 |
| Goodman, JJ | 1 |
| Hruza, LL | 1 |
| Jeffes, EW | 4 |
| Ling, MR | 1 |
| Phillips, TJ | 1 |
| Rallis, TM | 1 |
| Scher, RK | 1 |
| Taylor, CR | 1 |
| Weinstein, GD | 3 |
| Marmur, ES | 1 |
| Schmults, CD | 1 |
| Goldberg, DJ | 2 |
| Schleier, P | 1 |
| Hyckel, P | 1 |
| Berndt, A | 1 |
| Bode, HP | 1 |
| Albrecht, V | 1 |
| Hindermann, W | 1 |
| Kosmehl, H | 1 |
| Zenk, W | 1 |
| Schumann, D | 1 |
| Stiefelhagen, P | 1 |
| Siddiqui, MA | 1 |
| Perry, CM | 1 |
| Scott, LJ | 1 |
| Kormeili, T | 1 |
| Gold, MH | 6 |
| Goldman, MP | 4 |
| Akita, Y | 1 |
| Kozaki, K | 1 |
| Nakagawa, A | 1 |
| Saito, T | 1 |
| Ito, S | 1 |
| Tamada, Y | 1 |
| Fujiwara, S | 1 |
| Nishikawa, N | 1 |
| Uchida, K | 1 |
| Yoshikawa, K | 1 |
| Noguchi, T | 1 |
| Miyaishi, O | 1 |
| Shimozato, K | 1 |
| Saga, S | 1 |
| Matsumoto, Y | 1 |
| Ericson, MB | 2 |
| Sandberg, C | 2 |
| Gudmundson, F | 1 |
| Karlsson, M | 1 |
| Ros, AM | 1 |
| Rosén, A | 1 |
| Larkö, O | 1 |
| Rosdahl, I | 2 |
| Jorizzo, JL | 1 |
| Thissen, MR | 1 |
| Kuijpers, DI | 1 |
| Neumann, HA | 2 |
| Kim, HS | 1 |
| Yoo, JY | 1 |
| Cho, KH | 1 |
| Kwon, OS | 1 |
| Moon, SE | 1 |
| Zelickson, B | 1 |
| Counters, J | 1 |
| Coles, C | 1 |
| Selim, M | 1 |
| Tarstedt, M | 1 |
| Svanberg, K | 1 |
| Robles, CA | 1 |
| Garcia-Zuazaga, J | 1 |
| Cooper, KD | 1 |
| Baron, ED | 1 |
| Blecha-Thalhammer, U | 1 |
| Kittler, H | 1 |
| Hönigsmann, H | 2 |
| Kreutzer, K | 1 |
| Bonnekoh, B | 1 |
| Franke, I | 1 |
| Gollnick, H | 1 |
| Breuninger, H | 1 |
| Angell-Petersen, E | 1 |
| Sørensen, R | 1 |
| Warloe, T | 1 |
| Soler, AM | 1 |
| Moan, J | 1 |
| Peng, Q | 1 |
| Giercksky, KE | 1 |
| de Graaf, YG | 1 |
| Kennedy, C | 1 |
| Wolterbeek, R | 1 |
| Collen, AF | 1 |
| Willemze, R | 1 |
| Bouwes Bavinck, JN | 1 |
| Richey, DF | 2 |
| Nestor, MS | 2 |
| Kauvar, AN | 1 |
| Taub, AF | 1 |
| Geronemus, RG | 1 |
| Ritvo, EC | 1 |
| Gilbert, DJ | 1 |
| Alster, TS | 1 |
| Anderson, RR | 1 |
| Bank, DE | 1 |
| Carruthers, A | 1 |
| Carruthers, J | 1 |
| Hanke, CW | 2 |
| Rigel, DS | 1 |
| Robins, P | 1 |
| Spencer, JM | 1 |
| Zelickson, BD | 1 |
| Babilas, P | 2 |
| Kohl, E | 1 |
| Maisch, T | 1 |
| Bäcker, H | 1 |
| Gross, B | 1 |
| Branzan, AL | 1 |
| Bäumler, W | 2 |
| Landthaler, M | 4 |
| Fritsch, C | 5 |
| Ruzicka, T | 5 |
| Wulf, HC | 3 |
| Pavel, S | 1 |
| Stender, I | 1 |
| Bakker-Wensveen, CA | 1 |
| Kasche, A | 1 |
| Luderschmidt, S | 1 |
| Ring, J | 1 |
| Hein, R | 1 |
| Rivard, J | 1 |
| Ozog, D | 1 |
| Ibbotson, S | 2 |
| Woods, J | 1 |
| Brancaleon, L | 1 |
| Lesar, A | 1 |
| Goodman, C | 1 |
| Skiveren, J | 1 |
| Haedersdal, M | 2 |
| Philipsen, PA | 2 |
| Wiegell, SR | 2 |
| Caekelbergh, K | 1 |
| Annemans, L | 1 |
| Lambert, J | 1 |
| Roelandts, R | 2 |
| Maydan, E | 1 |
| Nootheti, PK | 2 |
| Morton, C | 1 |
| Campbell, S | 1 |
| Gupta, G | 1 |
| Lear, J | 1 |
| Zaki, I | 1 |
| Walton, S | 1 |
| Kerrouche, N | 2 |
| Thomas, G | 1 |
| Soto, P | 1 |
| Tschen, EH | 1 |
| Wong, DS | 1 |
| Dunlap, FE | 1 |
| Houlihan, A | 2 |
| Ferdon, MB | 1 |
| Kalisiak, MS | 1 |
| Rao, J | 1 |
| Alexiades-Armenakas, M | 1 |
| Morton, CA | 4 |
| Bissonnette, R | 2 |
| Basset-Seguin, N | 1 |
| Perrett, CM | 1 |
| McGregor, JM | 1 |
| Warwick, J | 1 |
| Karran, P | 1 |
| Leigh, IM | 1 |
| Proby, CM | 1 |
| Harwood, CA | 1 |
| Marcus, SL | 1 |
| Lundahl, S | 1 |
| Ferdon, ME | 1 |
| Batchelor, RJ | 1 |
| Stables, GI | 1 |
| Stringer, MR | 1 |
| Capezzera, R | 1 |
| Sala, R | 1 |
| Venturini, M | 1 |
| Calzavara-Pinton, P | 1 |
| Harvie, SE | 1 |
| Borelli, C | 1 |
| Herzinger, T | 1 |
| Merk, K | 1 |
| Berking, C | 1 |
| Kunte, C | 1 |
| Plewig, G | 1 |
| Degitz, K | 1 |
| Katz, BE | 1 |
| Truong, S | 1 |
| Maiwald, DC | 1 |
| Frew, KE | 1 |
| George, D | 1 |
| Lehmann, P | 2 |
| Moloney, FJ | 1 |
| Collins, P | 2 |
| Wolfe, CM | 1 |
| Hatfield, K | 1 |
| Cognetta, AB | 1 |
| Fauteck, JD | 1 |
| Ackermann, G | 1 |
| Birkel, M | 1 |
| Breuer, M | 1 |
| Moor, AC | 1 |
| Ebeling, A | 1 |
| Ortland, C | 1 |
| Travnik, R | 1 |
| Werner, A | 1 |
| de Haas, ER | 1 |
| de Vijlder, HC | 1 |
| Sterenborg, HJ | 1 |
| Robinson, DJ | 1 |
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| Sauerwald, A | 1 |
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| Reimann-Weber, A | 1 |
| Tosca, AD | 1 |
| Balas, CJ | 1 |
| Stefanidou, MP | 1 |
| Katsantonis, JC | 1 |
| Georgiou, SK | 1 |
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| Fergin, PE | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Formulation of 5-aminolevulinic Acid With Dimethylsulfoxide in Photodynamic Therapy for Treatment of Actinic Keratosis[NCT01459393] | Phase 3 | 137 participants (Actual) | Interventional | 2010-11-30 | Completed | ||
| A Multicenter, Double Blind, Vehicle-Controlled, Randomized Study of Photodynamic Therapy (PDT) With Metvix 160 Mg/g Cream and Aktilite CL128 LED Light in Patients With Multiple Actinic Keratosis on the Face and/or Scalp[NCT00306800] | Phase 3 | 80 participants (Anticipated) | Interventional | 2007-09-30 | Completed | ||
| A Multicenter, Double Blind, Vehicle-controlled, Randomized Study of Photodynamic Therapy (PDT) With Metvix 160 mg/g Cream and Aktilite CL128 LED Light in Patients With Multiple Actinic Keratosis on the Face and/or Scalp[NCT00304239] | Phase 3 | 131 participants (Actual) | Interventional | 2006-03-13 | Completed | ||
| A Clinical Trial of ALA Photodynamic Therapy for Treatment of Actinic Cheilitis in Patients With Squamous Cell Carcinoma of the Lip.[NCT00868088] | Phase 4 | 34 participants (Anticipated) | Interventional | 2009-07-31 | Completed | ||
| A Randomized Half-side Comparative Trial of Fractional Laser-assisted Daylight Photodynamic Therapy Versus Daylight Photodynamic Therapy in Organ Transplant Recipients With Multiple Actinic Keratoses of the Scalp or Forehead[NCT01898936] | 12 participants (Actual) | Interventional | 2013-08-31 | Completed | |||
| Topical Imiquimod 5% Cream Therapy Versus Photodynamic Therapy With Methyl-aminolaevulinate 16% Cream of Actinic Keratoses in Organ Transplant Recipients[NCT01538901] | Phase 4 | 10 participants (Actual) | Interventional | 2012-09-30 | Terminated (stopped due to prolonged recruitment phase) | ||
| Interferon Alpha Therapy for Cervical CIN I and HPV Infection[NCT06137950] | Phase 1 | 90 participants (Anticipated) | Interventional | 2023-11-07 | Recruiting | ||
| Photodynamic Therapy for Treatment of Cutaneous Squamous Cell Carcinoma in Situ[NCT03025724] | 40 participants (Anticipated) | Interventional | 2017-01-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
An AE was any untoward medical occurrence in a participant or clinical investigation participant administered a pharmaceutical product and which does not necessarily had a causal relationship with this treatment. An AE can therefore be any unfavorable and unintended sign (including an abnormal laboratory value), symptom, or disease temporally associated with the use of a medicinal (investigational) product, whether or not related to the medicinal (investigational) product. Number of participants with at least one treatment site adverse events were reported. (NCT00304239)
Timeframe: From start of study drug administration up to Week 13
| Intervention | Participants (Count of Participants) |
|---|---|
| Metvix-PDT | 61 |
| Vehicle-PDT | 27 |
Participant complete response rate was defined as the percentage of participants with complete response. Complete response was defined as the complete disappearance of the lesion determined by clinical assessment (visual inspection and palpation) by an investigator. (NCT00304239)
Timeframe: At Week 13
| Intervention | Percentage of participants (Number) |
|---|---|
| Metvix-PDT | 68.4 |
| Vehicle-PDT | 6.9 |
Lesion complete response rate was defined as the percentage of pre-existing and treated lesions at baseline that were assessed as clear (complete disappearance of the lesion, visually and by palpation) after treatment. Percentage of lesions reported by location. (NCT00304239)
Timeframe: At Week 13
| Intervention | Percentage of lesions (Number) | |
|---|---|---|
| Face | Scalp | |
| Metvix-PDT | 89 | 81 |
| Vehicle-PDT | 28 | 30 |
28 reviews available for aminolevulinic acid and Keratoderma Blennorrhagicum
| Article | Year |
|---|---|
Pretreatment to enhance protoporphyrin IX accumulation in photodynamic therapy.
Topics: Aminolevulinic Acid; Animals; Humans; Keratosis; Photochemotherapy; Photosensitizing Agents; Protopo | 2009 |
Photodynamic therapy for nonmelanoma skin cancers. Current review and update.
Topics: Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Dihematoporph | 2003 |
Topical photodynamic therapy: a new tool in cosmetic dermatology.
Topics: Acne Vulgaris; Administration, Topical; Aminolevulinic Acid; Hair Removal; Humans; Keratosis; Photoc | 2003 |
Topical and light-based treatments for actinic keratoses.
Topics: Adjuvants, Immunologic; Administration, Topical; Aminolevulinic Acid; Aminoquinolines; Antineoplasti | 2003 |
A review of laser and photodynamic therapy for the treatment of nonmelanoma skin cancer.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Basal Cell; Clinical Trials as Topic; Humans; Ker | 2004 |
Topical methyl aminolevulinate.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Carcinoma, Basal Cell; Humans; Keratosis; Photochemo | 2004 |
Topical photodynamic therapy in clinical dermatology.
Topics: Adult; Aminolevulinic Acid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Humans; Keratosis; Phot | 2004 |
5-aminolevulinic acid photodynamic therapy: where we have been and where we are going.
Topics: Acne Vulgaris; Administration, Cutaneous; Aminolevulinic Acid; Clinical Trials as Topic; Humans; Ker | 2004 |
Current and novel treatment options for actinic keratosis.
Topics: Aminolevulinic Acid; Aminoquinolines; Cryotherapy; Diclofenac; Fluorouracil; Gels; Humans; Imiquimod | 2004 |
[The wider application of photodynamic therapy in dermatology].
Topics: Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Dermatology; Humans; Keratosis; Photoch | 2005 |
Clinical efficacy of methyl aminolaevulinate photodynamic therapy in basal cell carcinoma and solar keratosis.
Topics: Adult; Aminolevulinic Acid; Carcinoma, Basal Cell; Humans; Keratosis; Photochemotherapy; Photosensit | 2005 |
Photodynamic therapy of dermatoses other than non-melanoma skin cancer.
Topics: Administration, Topical; Aminolevulinic Acid; Humans; Keratosis; Photochemotherapy; Photosensitizing | 2005 |
Photodynamic therapy in dermatology: current concepts in the treatment of skin cancer.
Topics: Aminolevulinic Acid; Carcinoma, Basal Cell; Clinical Trials as Topic; Humans; Keratosis; Photochemot | 2005 |
Current treatments of actinic keratosis.
Topics: Aminolevulinic Acid; Clinical Trials as Topic; Cryosurgery; Humans; Keratosis; Photochemotherapy; Ph | 2006 |
Fluorescence diagnosis and photodynamic therapy in dermatology from experimental state to clinic standard methods.
Topics: Aminolevulinic Acid; Fluorescence; Humans; Keratosis; Light; Photochemotherapy; Photosensitizing Age | 2006 |
Photodynamic therapy for actinic keratoses.
Topics: Aminolevulinic Acid; Humans; Keratosis; Photochemotherapy; Photosensitizing Agents; Ultraviolet Rays | 2007 |
Aminolevulinic acid photodynamic therapy for actinic keratoses/actinic cheilitis/acne: vascular lasers.
Topics: Acne Vulgaris; Aminolevulinic Acid; Cheilitis; Humans; Keratosis; Low-Level Light Therapy; Photochem | 2007 |
Methyl aminolevulinate: actinic keratoses and Bowen's disease.
Topics: Aminolevulinic Acid; Bowen's Disease; Facial Dermatoses; Humans; Keratosis; Photochemotherapy; Photo | 2007 |
Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: an international consensus. International Society for Photodynamic Therapy in Dermatology, 2005.
Topics: Aminolevulinic Acid; Australia; Basal Cell Nevus Syndrome; Bowen's Disease; Carcinoma, Basal Cell; C | 2007 |
Aminolevulinic acid and photodynamic combination therapy in the treatment of actinic keratoses: caring for the patient.
Topics: Aminolevulinic Acid; Heme; Humans; Keratosis; Nurse's Role; Nursing Assessment; Photochemotherapy; P | 2007 |
Methyl aminolaevulinate-photodynamic therapy: a review of clinical trials in the treatment of actinic keratoses and nonmelanoma skin cancer.
Topics: Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Humans; Keratosis; Photochemotherapy; P | 2007 |
Photodynamic therapy update 2007.
Topics: Acne Vulgaris; Administration, Topical; Aminolevulinic Acid; Animals; Clinical Trials as Topic; Fema | 2007 |
ALA and its clinical impact, from bench to bedside.
Topics: Aminolevulinic Acid; Dendritic Cells; Fluorescence; Humans; Keratosis; Lymphocytes; Macrophages; Neo | 2008 |
Photodynamic therapy in dermatology.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cel | 1998 |
Topical 5-aminolevulinic acid and photodynamic therapy in dermatology: a minireview.
Topics: Administration, Topical; Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Clinical Trial | 2001 |
Guidelines for topical photodynamic therapy: report of a workshop of the British Photodermatology Group.
Topics: Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Health Care Costs; Humans; Keratosis; L | 2002 |
Levulan: the first approved topical photosensitizer for the treatment of actinic keratosis.
Topics: Aminolevulinic Acid; Clinical Trials as Topic; Humans; Keratosis; Photochemotherapy; Photosensitizin | 2002 |
The emerging role of 5-ALA-PDT in dermatology: is PDT superior to standard treatments?
Topics: Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Humans; Keratosis; Photochemotherapy; P | 2002 |
40 trials available for aminolevulinic acid and Keratoderma Blennorrhagicum
| Article | Year |
|---|---|
Photodynamic therapy with methyl aminolevulinate for prevention of new skin lesions in transplant recipients: a randomized study.
Topics: Administration, Topical; Adult; Aged; Aminolevulinic Acid; Cryotherapy; Europe; Female; Humans; Immu | 2008 |
Topical methyl-aminolevulinate photodynamic therapy using red light-emitting diode light for treatment of multiple actinic keratoses: A randomized, double-blind, placebo-controlled study.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Double-Blind Method; F | 2008 |
Photodynamic therapy using topical methyl 5-aminolevulinate compared with cryotherapy for actinic keratosis: A prospective, randomized study.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cryotherapy; Female; H | 2002 |
Photodynamic therapy with topical methyl aminolevulinate for actinic keratosis: results of a prospective randomized multicenter trial.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Double-Blind Method; F | 2003 |
Photodynamic therapy with topical methyl aminolevulinate for actinic keratosis: results of a prospective randomized multicenter trial.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Double-Blind Method; F | 2003 |
Photodynamic therapy with topical methyl aminolevulinate for actinic keratosis: results of a prospective randomized multicenter trial.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Double-Blind Method; F | 2003 |
Photodynamic therapy with topical methyl aminolevulinate for actinic keratosis: results of a prospective randomized multicenter trial.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Double-Blind Method; F | 2003 |
A comparison of photodynamic therapy using topical methyl aminolevulinate (Metvix) with single cycle cryotherapy in patients with actinic keratosis: a prospective, randomized study.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cryosurgery; Double- | 2003 |
A comparison of photodynamic therapy using topical methyl aminolevulinate (Metvix) with single cycle cryotherapy in patients with actinic keratosis: a prospective, randomized study.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cryosurgery; Double- | 2003 |
A comparison of photodynamic therapy using topical methyl aminolevulinate (Metvix) with single cycle cryotherapy in patients with actinic keratosis: a prospective, randomized study.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cryosurgery; Double- | 2003 |
A comparison of photodynamic therapy using topical methyl aminolevulinate (Metvix) with single cycle cryotherapy in patients with actinic keratosis: a prospective, randomized study.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cryosurgery; Double- | 2003 |
A comparison of photodynamic therapy using topical methyl aminolevulinate (Metvix) with single cycle cryotherapy in patients with actinic keratosis: a prospective, randomized study.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cryosurgery; Double- | 2003 |
A comparison of photodynamic therapy using topical methyl aminolevulinate (Metvix) with single cycle cryotherapy in patients with actinic keratosis: a prospective, randomized study.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cryosurgery; Double- | 2003 |
A comparison of photodynamic therapy using topical methyl aminolevulinate (Metvix) with single cycle cryotherapy in patients with actinic keratosis: a prospective, randomized study.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cryosurgery; Double- | 2003 |
A comparison of photodynamic therapy using topical methyl aminolevulinate (Metvix) with single cycle cryotherapy in patients with actinic keratosis: a prospective, randomized study.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cryosurgery; Double- | 2003 |
A comparison of photodynamic therapy using topical methyl aminolevulinate (Metvix) with single cycle cryotherapy in patients with actinic keratosis: a prospective, randomized study.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cryosurgery; Double- | 2003 |
Short incubation PDT versus 5-FU in treating actinic keratoses.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Antimetabolites, Antineoplastic; Face; Female; Fluor | 2003 |
Topical photodynamic therapy in the treatment of actinic keratoses and Bowen's disease in transplant recipients.
Topics: Administration, Topical; Adult; Aged; Aminolevulinic Acid; Bowen's Disease; Case-Control Studies; Fe | 2004 |
A trial of short incubation, broad-area photodynamic therapy for facial actinic keratoses and diffuse photodamage.
Topics: Administration, Topical; Adult; Aged; Aminolevulinic Acid; Anesthetics, Local; Facial Dermatoses; Fe | 2004 |
Photodynamic therapy with aminolevulinic acid topical solution and visible blue light in the treatment of multiple actinic keratoses of the face and scalp: investigator-blinded, phase 3, multicenter trials.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Facial Dermatoses; Fem | 2004 |
A randomized controlled clinical trial of topical photodynamic therapy with methyl aminolaevulinate in the treatment of actinic keratoses in transplant recipients.
Topics: Adult; Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Female; Follow-Up Studies; Heart Transplant | 2004 |
A randomized controlled clinical trial of topical photodynamic therapy with methyl aminolaevulinate in the treatment of actinic keratoses in transplant recipients.
Topics: Adult; Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Female; Follow-Up Studies; Heart Transplant | 2004 |
A randomized controlled clinical trial of topical photodynamic therapy with methyl aminolaevulinate in the treatment of actinic keratoses in transplant recipients.
Topics: Adult; Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Female; Follow-Up Studies; Heart Transplant | 2004 |
A randomized controlled clinical trial of topical photodynamic therapy with methyl aminolaevulinate in the treatment of actinic keratoses in transplant recipients.
Topics: Adult; Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Female; Follow-Up Studies; Heart Transplant | 2004 |
Photodynamic therapy of actinic keratosis at varying fluence rates: assessment of photobleaching, pain and primary clinical outcome.
Topics: Aged; Aminolevulinic Acid; Dose-Response Relationship, Radiation; Female; Humans; Keratosis; Male; M | 2004 |
A randomized multicenter study to compare two treatment regimens of topical methyl aminolevulinate (Metvix)-PDT in actinic keratosis of the face and scalp.
Topics: Administration, Topical; Aged; Aminolevulinic Acid; Facial Dermatoses; Female; Humans; Keratosis; Ma | 2005 |
Efficacy of 3 different light doses in the treatment of actinic keratosis with 5-aminolevulinic acid photodynamic therapy: a randomized, observer-blinded, intrapatient, comparison study.
Topics: Aminolevulinic Acid; Female; Humans; Keratosis; Male; Photochemotherapy; Photosensitivity Disorders; | 2005 |
[Photodynamic therapy with methylaminooxopentanoate (Metvix) and a broad band light source (PhotoDyn 501): practical experiences in problem-patients with actinic keratoses and basal cell carcinomas].
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Female; Humans; Keratosis; Ligh | 2004 |
Porphyrin formation in actinic keratosis and basal cell carcinoma after topical application of methyl 5-aminolevulinate.
Topics: Administration, Topical; Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Double-Blind Method; Fema | 2006 |
Photodynamic therapy does not prevent cutaneous squamous-cell carcinoma in organ-transplant recipients: results of a randomized-controlled trial.
Topics: Adult; Aged; Aminolevulinic Acid; Carcinoma, Squamous Cell; Female; Humans; Keratosis; Male; Middle | 2006 |
In vitro and in vivo comparison of two different light sources for topical photodynamic therapy.
Topics: Adult; Aged; Aminolevulinic Acid; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; | 2006 |
Topical photodynamic therapy for prevention of new skin lesions in renal transplant recipients.
Topics: Administration, Topical; Adult; Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Female; Humans; Im | 2006 |
Photodynamic therapy induces less pain in patients treated with methyl aminolevulinate compared to aminolevulinic acid.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Keratosis; Male; Middle Aged; Ointment | 2006 |
Morphine gel 0.3% does not relieve pain during topical photodynamic therapy: a randomized, double-blind, placebo-controlled study.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Double-Blind Method; Gel | 2006 |
Economic evaluation of methyl aminolaevulinate-based photodynamic therapy in the management of actinic keratosis and basal cell carcinoma.
Topics: Aminolevulinic Acid; Belgium; Carcinoma, Basal Cell; Cost-Benefit Analysis; Cryosurgery; Decision Ma | 2006 |
Intraindividual, right-left comparison of topical methyl aminolaevulinate-photodynamic therapy and cryotherapy in subjects with actinic keratoses: a multicentre, randomized controlled study.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Cryosurgery; Esthetics; Facial Dermatoses; Female; Hum | 2006 |
Photodynamic therapy using aminolaevulinic acid for patients with nonhyperkeratotic actinic keratoses of the face and scalp: phase IV multicentre clinical trial with 12-month follow up.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Facial Dermatoses; Fem | 2006 |
Photodynamic therapy using aminolaevulinic acid for patients with nonhyperkeratotic actinic keratoses of the face and scalp: phase IV multicentre clinical trial with 12-month follow up.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Facial Dermatoses; Fem | 2006 |
Photodynamic therapy using aminolaevulinic acid for patients with nonhyperkeratotic actinic keratoses of the face and scalp: phase IV multicentre clinical trial with 12-month follow up.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Facial Dermatoses; Fem | 2006 |
Photodynamic therapy using aminolaevulinic acid for patients with nonhyperkeratotic actinic keratoses of the face and scalp: phase IV multicentre clinical trial with 12-month follow up.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Facial Dermatoses; Fem | 2006 |
Treatment of post-transplant premalignant skin disease: a randomized intrapatient comparative study of 5-fluorouracil cream and topical photodynamic therapy.
Topics: Administration, Topical; Aged; Aminolevulinic Acid; Antimetabolites, Antineoplastic; Bowen's Disease | 2007 |
Does ambient light contribute to the therapeutic effects of topical photodynamic therapy (PDT) using aminolevulinic acid HCl (ALA)?
Topics: Aminolevulinic Acid; Humans; Keratosis; Laser Therapy; Photochemotherapy; Photosensitizing Agents | 2007 |
Clinical and echographic analysis of photodynamic therapy using methylaminolevulinate as sensitizer in the treatment of photodamaged facial skin.
Topics: Aged; Aminolevulinic Acid; Female; Humans; Hyperpigmentation; Keratosis; Male; Middle Aged; Patient | 2007 |
Effect of subcutaneous infiltration anesthesia on pain in photodynamic therapy: a controlled open pilot trial.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Anesthesia, Local; Female; Gels; Humans; Keratosis; Ma | 2007 |
Efficacy of microdermabrasion preceding ALA application in reducing the incubation time of ALA in laser PDT.
Topics: Acne Vulgaris; Administration, Topical; Adult; Aminolevulinic Acid; Erythema; Humans; Keratosis; Las | 2007 |
Randomized, double-blind, prospective study to compare topical 5-aminolaevulinic acid methylester with topical 5-aminolaevulinic acid photodynamic therapy for extensive scalp actinic keratosis.
Topics: Administration, Topical; Aged; Aged, 80 and over; Aminolevulinic Acid; Double-Blind Method; Humans; | 2007 |
Split-face-study using two different light sources for topical PDT of actinic keratoses:non-inferiority of the LED system.
Topics: Administration, Topical; Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Keratosis; Li | 2008 |
Topical photodynamic therapy for dermatologic disorders: results and complications.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Dermatitis, Phototox | 2007 |
Continuous activation of PpIX by daylight is as effective as and less painful than conventional photodynamic therapy for actinic keratoses; a randomized, controlled, single-blinded study.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Dose-Response Relationship, Drug; Facial Dermatoses; F | 2008 |
Multicentre intraindividual randomized trial of topical methyl aminolaevulinate-photodynamic therapy vs. cryotherapy for multiple actinic keratoses on the extremities.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cryosurgery; Female; | 2008 |
Photodynamic therapy with topical application of 5-aminolevulinic acid in the treatment of actinic keratoses: an initial clinical study.
Topics: Administration, Topical; Adult; Aminolevulinic Acid; Female; Humans; Keratosis; Male; Photochemother | 1996 |
Photodynamic therapy of actinic keratosis with topical 5-aminolevulinic acid. A pilot dose-ranging study.
Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Aminolevulinic Acid; Dose-Response Relationship, | 1997 |
Long-pulse dye laser for photodynamic therapy: investigations in vitro and in vivo.
Topics: Adolescent; Adult; Aged; Aminolevulinic Acid; Cells, Cultured; Female; Follow-Up Studies; Humans; In | 1999 |
Topical delta-aminolevulinic acid-based photodynamic therapy for Japanese actinic keratoses.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Arm; Asian People; Carcinoma, Squamous Cell; Facial De | 2000 |
Photodynamic therapy of actinic keratoses with topical aminolevulinic acid hydrochloride and fluorescent blue light.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Kerato | 2001 |
Photodynamic therapy with violet light and topical 6-aminolaevulinic acid in the treatment of actinic keratosis, Bowen's disease and basal cell carcinoma.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Bowen's Disease; Carci | 2001 |
Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experience.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Humans; Keratosis; Ph | 1990 |
47 other studies available for aminolevulinic acid and Keratoderma Blennorrhagicum
| Article | Year |
|---|---|
Long methylaminolaevulinate application does not increase clinical efficacy of photodynamic therapy in actinic keratosis, but leads to collateral damage.
Topics: Aminolevulinic Acid; Humans; Keratosis; Keratosis, Actinic; Photochemotherapy; Photosensitizing Agen | 2017 |
Milia en plaque.
Topics: Aminolevulinic Acid; Biopsy; Diagnosis, Differential; Ear Diseases; Ear, External; Epithelial Cells; | 2013 |
Intense pulsed light combined with methyl aminolaevulinate for treating actinic keratoses and photoaged skin of the dorsal hands has considerable advantages. However, is it worth the extra expense?
Topics: Aminolevulinic Acid; Humans; Keratosis; Keratosis, Actinic; Photochemotherapy | 2017 |
Letter: photodynamic therapy with methyl aminolevulinate induces phototoxic reactions on areas of the nose adjacent to basal cell carcinomas and actinic keratoses.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Dermatitis, Phototoxic; Humans; | 2008 |
Aminolaevulinic acid diffusion characteristics in 'in vitro' normal human skin and actinic keratosis: implications for topical photodynamic therapy.
Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Aminolevulinic Acid; Analysis of Variance; Carbo | 2008 |
Erosive pustular dermatosis of the scalp following topical methylaminolaevulinate photodynamic therapy.
Topics: Administration, Topical; Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Keratosis; Photoche | 2009 |
Photodynamic photorejuvenation.
Topics: Administration, Topical; Aminolevulinic Acid; Female; Humans; Keratosis; Male; Middle Aged; Photoche | 2002 |
New treatments for actinic keratoses.
Topics: Administration, Topical; Aminolevulinic Acid; Aminoquinolines; Dermatologic Agents; Diclofenac; Fluo | 2002 |
Evidence-based evaluation of photodynamic therapy of actinic keratoses.
Topics: Aminolevulinic Acid; Clinical Trials, Phase II as Topic; Humans; Keratosis; Photochemotherapy; Photo | 2003 |
ALA/PDT in the treatment of actinic keratosis: spot versus confluent therapy.
Topics: Adult; Aged; Aminolevulinic Acid; Face; Female; Humans; Keratosis; Male; Middle Aged; Photochemother | 2003 |
Topical 5-aminolaevulinic acid photodynamic therapy for cutaneous lesions: outcome and comparison of light sources.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; England | 2003 |
Photodynamic therapy for actinic keratosis followed by 5-fluorouracil reaction.
Topics: Aminolevulinic Acid; Antimetabolites, Antineoplastic; Emollients; Female; Fluorouracil; Humans; Kera | 2003 |
Photodynamic therapy of virus-associated epithelial tumours of the face in organ transplant recipients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Facial Neoplasms; Humans; Keratosis | 2004 |
[In actinic keratosis and basal cell carcinoma. The power of light heals without scars].
Topics: Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Humans; Keratosis; Middle Aged; Ointments; Photoch | 2003 |
Cyclooxygenase-2 is a possible target of treatment approach in conjunction with photodynamic therapy for various disorders in skin and oral cavity.
Topics: Aminolevulinic Acid; Bowen's Disease; Carcinoma, Squamous Cell; Cell Division; Cell Line, Tumor; Cyc | 2004 |
Topical photodynamic therapy using intense pulsed light for treatment of actinic keratosis: clinical and histopathologic evaluation.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Keratosis; Male; Middle Aged; Photoche | 2005 |
Light patch: preliminary report of a novel form of blue light delivery for the treatment of actinic keratosis.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Humans; Keratosis; Male; Middle Aged; Photoche | 2005 |
Correlation between macroscopic fluorescence and protoporphyrin IX content in psoriasis and actinic keratosis following application of aminolevulinic acid.
Topics: Aminolevulinic Acid; DNA; Humans; Keratosis; Protoporphyrins; Psoriasis; Spectrometry, Fluorescence | 2005 |
[Reader's letter concerning K. Kreutzer, B.Bonnekoh, I. Franke, H. Gollnick. Photodynamic therapy with methylaminooxopentanoate (Metvix) and a broad band light source (Photdyn 501): practical experiences in problem patients with actinic keratoses and basa
Topics: Aminolevulinic Acid; Carcinoma, Basal Cell; Humans; Keratosis; Photochemotherapy; Photosensitivity D | 2005 |
Implementing photodynamic therapy.
Topics: Acne Vulgaris; Aminolevulinic Acid; Attitude to Health; Humans; Keratosis; Photochemotherapy; Photos | 2006 |
The use of photodynamic therapy in dermatology: results of a consensus conference.
Topics: Aminolevulinic Acid; Carcinoma, Basal Cell; Clinical Trials as Topic; Humans; Keratosis; Photochemot | 2006 |
Henry Ford Hospital dermatology experience with Levulan Kerastick and blue light photodynamic therapy.
Topics: Acne Vulgaris; Adult; Aminolevulinic Acid; Female; Hidradenitis Suppurativa; Humans; Keratosis; Male | 2006 |
Clinical and research applications of photodynamic therapy in dermatology: experience of the Scottish PDT Centre.
Topics: Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Humans; Keratosis; Neoplasm Recurrence, | 2006 |
Development of a keratoacanthoma after topical photodynamic therapy with 5-aminolevulinic acid.
Topics: Administration, Topical; Aminolevulinic Acid; Humans; Keratoacanthoma; Keratosis; Male; Middle Aged; | 2006 |
Aminolevulinic acid-photodynamic therapy for photorejuvenation.
Topics: Adult; Aged; Aminolevulinic Acid; Female; Humans; Keratosis; Male; Middle Aged; Photochemotherapy; P | 2007 |
Chemopreventative thoughts for photodynamic therapy.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Humans; Keratosis; Mice; Neoplasms, Radiatio | 2007 |
Successful treatment of scalp actinic keratoses with photodynamic therapy using ambient light.
Topics: Aged, 80 and over; Aminolevulinic Acid; Humans; Keratosis; Male; Photochemotherapy; Photosensitizing | 2007 |
Cellulitis as a postprocedural complication of topical 5-aminolevulinic acid photodynamic therapy in the treatment of actinic keratosis.
Topics: Adult; Aged, 80 and over; Aminolevulinic Acid; Cellulitis; Face; Humans; Keratosis; Male; Middle Age | 2007 |
Fluorescence characteristics and pharmacokinetic properties of a novel self-adhesive 5-ALA patch for photodynamic therapy of actinic keratoses.
Topics: Adhesives; Administration, Cutaneous; Aged; Aged, 80 and over; Aminolevulinic Acid; Case-Control Stu | 2008 |
Fractionated aminolevulinic acid-photodynamic therapy provides additional evidence for the use of PDT for non-melanoma skin cancer.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Female; | 2008 |
Pharmacoeconomic analysis of the treatment of multiple actinic keratoses.
Topics: Aminolevulinic Acid; Aminoquinolines; Clinical Trials, Phase III as Topic; Combined Modality Therapy | 2008 |
Images in clinical medicine. Fluorescence diagnosis of subclinical actinic keratoses.
Topics: Aged; Aminolevulinic Acid; Fluorescence; Humans; Keratosis; Male; Ultraviolet Rays | 2008 |
Transcutaneous electrical nerve stimulation for pain relief during photodynamic therapy of actinic keratoses.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Humans; Keratosis; Male; Middle Aged; Pain; Pain Measu | 2008 |
Are cutaneous vessels one of the targets of resurfacing with photodynamic therapy?
Topics: Aminolevulinic Acid; Humans; Keratosis; Male; Photochemotherapy; Photosensitizing Agents; Skin; Tela | 2008 |
Keratosis lichenoides chronica: response to photodynamic therapy.
Topics: Aminolevulinic Acid; Chronic Disease; Female; Humans; Keratosis; Lichenoid Eruptions; Middle Aged; P | 2008 |
Photodynamic therapy of epithelial skin tumours using delta-aminolaevulinic acid and desferrioxamine.
Topics: Aminolevulinic Acid; Bowen's Disease; Carcinoma, Basal Cell; Deferoxamine; Female; Humans; Keratosis | 1995 |
Topical photodynamic therapy with endogenous porphyrins after application of 5-aminolevulinic acid. An alternative treatment modality for solar keratoses, superficial squamous cell carcinomas, and basal cell carcinomas?
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cel | 1993 |
Influence of topical photodynamic therapy with 5-aminolevulinic acid on porphyrin metabolism.
Topics: Administration, Topical; Aminolevulinic Acid; Carcinoma, Basal Cell; Humans; Keratosis; Photochemoth | 1996 |
Development of malignant melanoma after repeated topical photodynamic therapy with 5-aminolevulinic acid at the exposed site.
Topics: Aged; Aged, 80 and over; Alopecia; Aminolevulinic Acid; Carcinoma, Squamous Cell; Follow-Up Studies; | 1997 |
Photodynamic treatment of skin malignancies with aminolevulinic acid. Emphasis on anatomical observations and in vivo erythema visual assessment.
Topics: Aminolevulinic Acid; Antineoplastic Agents; Carcinoma, Basal Cell; Erythema; Female; Follow-Up Studi | 1996 |
Primary clinical response and long-term follow-up of solar keratoses treated with topically applied 5-aminolevulinic acid and irradiation by different wave bands of light.
Topics: Administration, Topical; Aged; Aged, 80 and over; Aminolevulinic Acid; Erythema; Female; Fluorescenc | 1997 |
Preferential relative porphyrin enrichment in solar keratoses upon topical application of delta-aminolevulinic acid methylester.
Topics: Administration, Topical; Aminolevulinic Acid; Animals; Humans; In Vitro Techniques; Keratosis; Photo | 1998 |
From the Food and Drug Administration.
Topics: Administration, Topical; Aminolevulinic Acid; Antidepressive Agents; Humans; Keratosis; Penicillin G | 2000 |
Topical 5-aminolaevulinic acid photodynamic therapy for extensive scalp actinic keratoses.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Follow-Up Studies; Humans; Keratosis; Male; Photochemo | 2001 |
Aminolevulinic acid (Levulan) in photodynamic therapy of actinic keratoses.
Topics: Administration, Topical; Aminolevulinic Acid; Contraindications; Humans; Keratosis; Photochemotherap | 2001 |
Aminolevulinic acid hydrochloride with photodynamic therapy: efficacy outcomes and recurrence 4 years after treatment.
Topics: Administration, Cutaneous; Adult; Aged; Aminolevulinic Acid; Clinical Trials, Phase II as Topic; Fac | 2002 |
The evolving role of aminolevulinic acid hydrochloride with photodynamic therapy in photoaging.
Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Aminolevulinic Acid; Clinical Trials, Phase III | 2002 |