Page last updated: 2024-10-16

aminolevulinic acid and Invasiveness, Neoplasm

aminolevulinic acid has been researched along with Invasiveness, Neoplasm in 68 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Research Excerpts

ExcerptRelevanceReference
"To examine the utility and safety of photodynamic diagnosis (PDD) after oral administration of 5-aminolevulinic acid (5-ALA) (ALA-PDD) of non-muscle-invasive bladder cancer (NMIBC) using fluorescent-light (FL)-cystoscopy."9.22The clinical trial on the safety and effectiveness of the photodynamic diagnosis of non-muscle-invasive bladder cancer using fluorescent light-guided cystoscopy after oral administration of 5-aminolevulinic acid (5-ALA). ( Azuma, H; Fujimoto, K; Hirao, Y; Inoue, K; Ito, YM; Matsubara, A; Matsuyama, H; Mimata, H; Nagase, Y; Oyama, M; Ozono, S; Shiina, H; Shuin, T; Sugimura, Y; Ueno, M; Watanabe, H, 2016)
"Patient selection for transurethral resection of the bladder tumor using photodynamic diagnosis (PDD-TURBT) with oral 5-aminolevulinic acid (5-ALA) hydrochloride for non-muscle-invasive bladder cancer (NMIBC) is still unclear as to the best balance of risks (adverse events including hypotension) and benefits (reduction of intravesical recurrence)."8.31Risks and benefits of transurethral resection of the bladder tumor using photodynamic diagnosis with oral 5-aminolevulinic acid hydrochloride according to age and history of recurrence in patients with non-muscle invasive bladder cancer. ( Hirata, H; Hiroyoshi, T; Isoyama, N; Ito, H; Kobayashi, K; Matsumoto, H; Matsuyama, H; Misumi, T; Nakamura, K; Oka, S; Shiraishi, K, 2023)
"Photodynamic diagnosis (PDD) with administration of oral aminolevulinic acid (ALA) prior to transurethral resection of bladder tumor (TURBT) can now be used for non-muscle invasive bladder cancer (NMIBC) in clinical settings in Japan."8.12Real-world experience with 5-aminolevulinic acid for photodynamic diagnosis of bladder cancer (2nd report): Reduced bladder recurrence after PDD-TURBT. ( Fukuhara, H; Furihata, M; Inoue, K; Karashima, T; Kurabayashi, A; Lai, HW; Yamamoto, S, 2022)
"5-Aminolevulinic acid-induced PpIX fluorescence was assessed in GL261-Luc2 cells in vitro and in vivo after implantation in mouse brains, at an invading glioma growth stage, simulating residual tumor."7.88Scanning Fiber Endoscope Improves Detection of 5-Aminolevulinic Acid-Induced Protoporphyrin IX Fluorescence at the Boundary of Infiltrative Glioma. ( Belykh, E; Byvaltsev, VA; Hu, D; Martirosyan, NL; Miller, EJ; Nakaji, P; Nelson, LY; Preul, MC; Scheck, AC; Seibel, EJ; Woolf, EC, 2018)
" SFE may allow accurate imaging of 5-aminolevulinic acid labeling of gliomas and other tumor types when current detection techniques have failed to provide reliable visualization."7.88Scanning Fiber Endoscope Improves Detection of 5-Aminolevulinic Acid-Induced Protoporphyrin IX Fluorescence at the Boundary of Infiltrative Glioma. ( Belykh, E; Byvaltsev, VA; Hu, D; Martirosyan, NL; Miller, EJ; Nakaji, P; Nelson, LY; Preul, MC; Scheck, AC; Seibel, EJ; Woolf, EC, 2018)
"Fluorescence-guided surgery with protoporphyrin IX (PpIX) as a photodiagnostic marker is gaining acceptance for resection of malignant gliomas."7.88Scanning Fiber Endoscope Improves Detection of 5-Aminolevulinic Acid-Induced Protoporphyrin IX Fluorescence at the Boundary of Infiltrative Glioma. ( Belykh, E; Byvaltsev, VA; Hu, D; Martirosyan, NL; Miller, EJ; Nakaji, P; Nelson, LY; Preul, MC; Scheck, AC; Seibel, EJ; Woolf, EC, 2018)
"This study was undertaken to evaluate the clinical value of photodynamic diagnosis (PDD) with intravesical and oral instillation of 5-aminolevulinic acid (ALA) (ALA-PDD), and transurethral resection of bladder tumor (TURBT) guided by ALA-PDD (PDD-TURBT) for nonmuscle invasive bladder cancer."7.78Comparison between intravesical and oral administration of 5-aminolevulinic acid in the clinical benefit of photodynamic diagnosis for nonmuscle invasive bladder cancer. ( Fukuhara, H; Furihata, M; Iiyama, T; Inoue, K; Kamada, M; Kurabayashi, A; Miyamura, M; Shimamoto, T; Shuin, T; Tanimura, M; Watanabe, H, 2012)
"ALA-PDD was shown to be safe and effective."6.82The clinical trial on the safety and effectiveness of the photodynamic diagnosis of non-muscle-invasive bladder cancer using fluorescent light-guided cystoscopy after oral administration of 5-aminolevulinic acid (5-ALA). ( Azuma, H; Fujimoto, K; Hirao, Y; Inoue, K; Ito, YM; Matsubara, A; Matsuyama, H; Mimata, H; Nagase, Y; Oyama, M; Ozono, S; Shiina, H; Shuin, T; Sugimura, Y; Ueno, M; Watanabe, H, 2016)
"Regarding safety, the adverse drug reactions were observed as grade 1 pruritus in 1 patient (0."6.82The clinical trial on the safety and effectiveness of the photodynamic diagnosis of non-muscle-invasive bladder cancer using fluorescent light-guided cystoscopy after oral administration of 5-aminolevulinic acid (5-ALA). ( Azuma, H; Fujimoto, K; Hirao, Y; Inoue, K; Ito, YM; Matsubara, A; Matsuyama, H; Mimata, H; Nagase, Y; Oyama, M; Ozono, S; Shiina, H; Shuin, T; Sugimura, Y; Ueno, M; Watanabe, H, 2016)
"The frequency of recurrence was lower and the time to recurrence was longer in the PDD-TURBT group than in the WL-TURBT group."5.72Real-world experience with 5-aminolevulinic acid for photodynamic diagnosis of bladder cancer (2nd report): Reduced bladder recurrence after PDD-TURBT. ( Fukuhara, H; Furihata, M; Inoue, K; Karashima, T; Kurabayashi, A; Lai, HW; Yamamoto, S, 2022)
"This study compared tumor recurrence among NMIBC patients who underwent TURBT under either white light cystoscopy (WL) or PDD."5.72Real-world experience with 5-aminolevulinic acid for photodynamic diagnosis of bladder cancer (2nd report): Reduced bladder recurrence after PDD-TURBT. ( Fukuhara, H; Furihata, M; Inoue, K; Karashima, T; Kurabayashi, A; Lai, HW; Yamamoto, S, 2022)
"The frequency of recurrence in NMIBC patients (cumulative number of recurrences/cumulative number of follow-up days, number of recurrences/10,000 days), including progression to muscle-invasive bladder cancer (MIBC), was 12."5.72Real-world experience with 5-aminolevulinic acid for photodynamic diagnosis of bladder cancer (2nd report): Reduced bladder recurrence after PDD-TURBT. ( Fukuhara, H; Furihata, M; Inoue, K; Karashima, T; Kurabayashi, A; Lai, HW; Yamamoto, S, 2022)
"Chordomas are very rare tumors of the skull base and the sacrum."5.465-Aminolevulinic acid-based photodynamic therapy of chordoma: In vitro experiments on a human tumor cell line. ( Cornelius, JF; Ebbert, L; Eismann, L; Kamp, MA; Petridis, AK; Senger, B; Sorg, RV; Steiger, HJ, 2017)
"To assess the efficacy of two treatment options for non-muscle-invasive bladder cancer (NMIBC): (1) transurethral resection (TUR) guided by fluorescence cystoscopy (FC) with the use of 5-aminolevulinic acid (5-ALA) and (2) single early instillation of doxorubicin in a single-center open-label prospective randomized study with a 2 × 2 factorial design."5.24Results of a prospective randomized study assessing the efficacy of fluorescent cystoscopy-assisted transurethral resection and single instillation of doxorubicin in patients with non-muscle-invasive bladder cancer. ( Krasny, SA; Minich, AA; Mokhort, AA; Polyakov, SL; Rolevich, AI; Sukonko, OG; Vasilevich, VY; Zhegalik, AG, 2017)
"To examine the utility and safety of photodynamic diagnosis (PDD) after oral administration of 5-aminolevulinic acid (5-ALA) (ALA-PDD) of non-muscle-invasive bladder cancer (NMIBC) using fluorescent-light (FL)-cystoscopy."5.22The clinical trial on the safety and effectiveness of the photodynamic diagnosis of non-muscle-invasive bladder cancer using fluorescent light-guided cystoscopy after oral administration of 5-aminolevulinic acid (5-ALA). ( Azuma, H; Fujimoto, K; Hirao, Y; Inoue, K; Ito, YM; Matsubara, A; Matsuyama, H; Mimata, H; Nagase, Y; Oyama, M; Ozono, S; Shiina, H; Shuin, T; Sugimura, Y; Ueno, M; Watanabe, H, 2016)
"Controversy exists regarding the therapeutic benefit and cost effectiveness of photodynamic diagnosis (PDD) with 5-aminolevulinic acid (5-ALA) or hexyl aminolevulinate (HAL) in addition to white-light cystoscopy (WLC) in the management of non-muscle-invasive bladder cancer (NMIBC)."4.89Hexyl aminolevulinate-guided fluorescence cystoscopy in the diagnosis and follow-up of patients with non-muscle-invasive bladder cancer: a critical review of the current literature. ( Babjuk, M; Catto, JW; Jichlinski, P; Rink, M; Shariat, SF; Stenzl, A; Stepp, H; Witjes, JA; Zaak, D, 2013)
"The clinical benefit of photodynamic diagnosis (PDD) with 5-aminolevulinic acid or hexaminolevulinate in addition to white-light cystoscopy (WLC) in bladder cancer has been discussed controversially."4.86Photodynamic diagnosis in non-muscle-invasive bladder cancer: a systematic review and cumulative analysis of prospective studies. ( Jacqmin, D; Jichlinski, P; Jocham, D; Kausch, I; Montorsi, F; Sommerauer, M; Stenzl, A; Vonthein, R; Ziegler, A, 2010)
"Patient selection for transurethral resection of the bladder tumor using photodynamic diagnosis (PDD-TURBT) with oral 5-aminolevulinic acid (5-ALA) hydrochloride for non-muscle-invasive bladder cancer (NMIBC) is still unclear as to the best balance of risks (adverse events including hypotension) and benefits (reduction of intravesical recurrence)."4.31Risks and benefits of transurethral resection of the bladder tumor using photodynamic diagnosis with oral 5-aminolevulinic acid hydrochloride according to age and history of recurrence in patients with non-muscle invasive bladder cancer. ( Hirata, H; Hiroyoshi, T; Isoyama, N; Ito, H; Kobayashi, K; Matsumoto, H; Matsuyama, H; Misumi, T; Nakamura, K; Oka, S; Shiraishi, K, 2023)
"Photodynamic diagnosis (PDD) with administration of oral aminolevulinic acid (ALA) prior to transurethral resection of bladder tumor (TURBT) can now be used for non-muscle invasive bladder cancer (NMIBC) in clinical settings in Japan."4.12Real-world experience with 5-aminolevulinic acid for photodynamic diagnosis of bladder cancer (2nd report): Reduced bladder recurrence after PDD-TURBT. ( Fukuhara, H; Furihata, M; Inoue, K; Karashima, T; Kurabayashi, A; Lai, HW; Yamamoto, S, 2022)
"Photodynamic diagnosis (PDD) using 5-aminolevulinic acid (5-ALA) is expected to be useful in preventing oversight of non-muscle-invasive bladder cancer (NMIBC) and in reducing the intravesical recurrence rate after transurethral resection of bladder tumor (TURBT)."4.02[Initial Experience of Photodynamic Diagnosis-Assisted Transurethral Resection of Bladder Tumor (PDD-TURBT)]. ( Inoue, T; Kanda, H; Kato, M; Masui, S; Nishikawa, K; Sasaki, T; Sugimura, Y; Sugino, Y; Yoshio, Y, 2021)
"Photodynamic therapy (PDT) has been reported as a treatment for cutaneous squamous cell carcinoma in situ (SCCis), but only limited data are available on the effectiveness of PDT with aminolevulinic acid (ALA-PDT)."3.96Photodynamic therapy for cutaneous squamous cell carcinoma in situ: Impact of anatomic location, tumor diameter, and incubation time on effectiveness. ( Christensen, SR; Kibbi, N; Leffell, DJ; Zhang, Y, 2020)
"5-Aminolevulinic acid-induced PpIX fluorescence was assessed in GL261-Luc2 cells in vitro and in vivo after implantation in mouse brains, at an invading glioma growth stage, simulating residual tumor."3.88Scanning Fiber Endoscope Improves Detection of 5-Aminolevulinic Acid-Induced Protoporphyrin IX Fluorescence at the Boundary of Infiltrative Glioma. ( Belykh, E; Byvaltsev, VA; Hu, D; Martirosyan, NL; Miller, EJ; Nakaji, P; Nelson, LY; Preul, MC; Scheck, AC; Seibel, EJ; Woolf, EC, 2018)
" SFE may allow accurate imaging of 5-aminolevulinic acid labeling of gliomas and other tumor types when current detection techniques have failed to provide reliable visualization."3.88Scanning Fiber Endoscope Improves Detection of 5-Aminolevulinic Acid-Induced Protoporphyrin IX Fluorescence at the Boundary of Infiltrative Glioma. ( Belykh, E; Byvaltsev, VA; Hu, D; Martirosyan, NL; Miller, EJ; Nakaji, P; Nelson, LY; Preul, MC; Scheck, AC; Seibel, EJ; Woolf, EC, 2018)
"Fluorescence-guided surgery with protoporphyrin IX (PpIX) as a photodiagnostic marker is gaining acceptance for resection of malignant gliomas."3.88Scanning Fiber Endoscope Improves Detection of 5-Aminolevulinic Acid-Induced Protoporphyrin IX Fluorescence at the Boundary of Infiltrative Glioma. ( Belykh, E; Byvaltsev, VA; Hu, D; Martirosyan, NL; Miller, EJ; Nakaji, P; Nelson, LY; Preul, MC; Scheck, AC; Seibel, EJ; Woolf, EC, 2018)
"This study was undertaken to evaluate the clinical value of photodynamic diagnosis (PDD) with intravesical and oral instillation of 5-aminolevulinic acid (ALA) (ALA-PDD), and transurethral resection of bladder tumor (TURBT) guided by ALA-PDD (PDD-TURBT) for nonmuscle invasive bladder cancer."3.78Comparison between intravesical and oral administration of 5-aminolevulinic acid in the clinical benefit of photodynamic diagnosis for nonmuscle invasive bladder cancer. ( Fukuhara, H; Furihata, M; Iiyama, T; Inoue, K; Kamada, M; Kurabayashi, A; Miyamura, M; Shimamoto, T; Shuin, T; Tanimura, M; Watanabe, H, 2012)
"ALA-PDD was shown to be safe and effective."2.82The clinical trial on the safety and effectiveness of the photodynamic diagnosis of non-muscle-invasive bladder cancer using fluorescent light-guided cystoscopy after oral administration of 5-aminolevulinic acid (5-ALA). ( Azuma, H; Fujimoto, K; Hirao, Y; Inoue, K; Ito, YM; Matsubara, A; Matsuyama, H; Mimata, H; Nagase, Y; Oyama, M; Ozono, S; Shiina, H; Shuin, T; Sugimura, Y; Ueno, M; Watanabe, H, 2016)
"Regarding safety, the adverse drug reactions were observed as grade 1 pruritus in 1 patient (0."2.82The clinical trial on the safety and effectiveness of the photodynamic diagnosis of non-muscle-invasive bladder cancer using fluorescent light-guided cystoscopy after oral administration of 5-aminolevulinic acid (5-ALA). ( Azuma, H; Fujimoto, K; Hirao, Y; Inoue, K; Ito, YM; Matsubara, A; Matsuyama, H; Mimata, H; Nagase, Y; Oyama, M; Ozono, S; Shiina, H; Shuin, T; Sugimura, Y; Ueno, M; Watanabe, H, 2016)
"Non-muscle-invasive bladder cancer (NMIBC) is associated with a high recurrence risk, partly because of the persistence of lesions following transurethral resection of bladder tumour (TURBT) due to the presence of multiple lesions and the difficulty in identifying the exact extent and location of tumours using standard white-light cystoscopy (WLC)."2.50Clinical and cost effectiveness of hexaminolevulinate-guided blue-light cystoscopy: evidence review and updated expert recommendations. ( Babjuk, M; Gontero, P; Jacqmin, D; Karl, A; Kruck, S; Mariappan, P; Palou Redorta, J; Stenzl, A; van Velthoven, R; Witjes, JA; Zaak, D, 2014)
"Residual tumour was significantly less often found after PDD (odds ratio: 0."2.46Photodynamic diagnosis in non-muscle-invasive bladder cancer: a systematic review and cumulative analysis of prospective studies. ( Jacqmin, D; Jichlinski, P; Jocham, D; Kausch, I; Montorsi, F; Sommerauer, M; Stenzl, A; Vonthein, R; Ziegler, A, 2010)
"Non-muscle invasive bladder cancer is the most expensive cancer to manage on a per patient basis due to the high recurrence rate, low mortality and the need for long term, often lifelong surveillance."2.44The economic benefit of photodynamic diagnosis in non-muscle invasive bladder cancer. ( Bunce, CJ; Dindyal, S; Nitkunan, T, 2008)
"This study compared tumor recurrence among NMIBC patients who underwent TURBT under either white light cystoscopy (WL) or PDD."1.72Real-world experience with 5-aminolevulinic acid for photodynamic diagnosis of bladder cancer (2nd report): Reduced bladder recurrence after PDD-TURBT. ( Fukuhara, H; Furihata, M; Inoue, K; Karashima, T; Kurabayashi, A; Lai, HW; Yamamoto, S, 2022)
"The frequency of recurrence was lower and the time to recurrence was longer in the PDD-TURBT group than in the WL-TURBT group."1.72Real-world experience with 5-aminolevulinic acid for photodynamic diagnosis of bladder cancer (2nd report): Reduced bladder recurrence after PDD-TURBT. ( Fukuhara, H; Furihata, M; Inoue, K; Karashima, T; Kurabayashi, A; Lai, HW; Yamamoto, S, 2022)
"The frequency of recurrence in NMIBC patients (cumulative number of recurrences/cumulative number of follow-up days, number of recurrences/10,000 days), including progression to muscle-invasive bladder cancer (MIBC), was 12."1.72Real-world experience with 5-aminolevulinic acid for photodynamic diagnosis of bladder cancer (2nd report): Reduced bladder recurrence after PDD-TURBT. ( Fukuhara, H; Furihata, M; Inoue, K; Karashima, T; Kurabayashi, A; Lai, HW; Yamamoto, S, 2022)
"Chordomas are very rare tumors of the skull base and the sacrum."1.465-Aminolevulinic acid-based photodynamic therapy of chordoma: In vitro experiments on a human tumor cell line. ( Cornelius, JF; Ebbert, L; Eismann, L; Kamp, MA; Petridis, AK; Senger, B; Sorg, RV; Steiger, HJ, 2017)
"Mean residual tumor volume (range) after iMRI-assisted surgery [0."1.40Maximizing the extent of resection and survival benefit of patients in glioblastoma surgery: high-field iMRI versus conventional and 5-ALA-assisted surgery. ( Bisdas, S; Ebner, FH; Ernemann, U; Honegger, J; Naegele, T; Roder, C; Tatagiba, M, 2014)
"Five-aminolevulinic acid (ALA) has received much attention recently as a new-generation photosensitive substance for photodynamic diagnosis (PDD)."1.40Photodynamic diagnosis using 5-aminolevulinic acid during gastrectomy for gastric cancer. ( Fukuhara, H; Hanazaki, K; Inoue, K; Kitagawa, H; Kobayashi, M; Maeda, H; Namikawa, T; Shiga, M; Shuin, T; Uemura, S, 2014)
"Analysis of residual tumor volumes, total resections and neurological outcomes demonstrate that iMRI may be significantly superior to 5-ALA and white-light surgery for glioblastomas at comparable peri- and postoperative morbidities."1.40Maximizing the extent of resection and survival benefit of patients in glioblastoma surgery: high-field iMRI versus conventional and 5-ALA-assisted surgery. ( Bisdas, S; Ebner, FH; Ernemann, U; Honegger, J; Naegele, T; Roder, C; Tatagiba, M, 2014)
"5-aminolevulinic acid (5-ALA) has gained importance as an intraoperative photodynamic diagnostic agent for the extirpation of malignant gliomas."1.36Intraoperative 5-aminolevulinic-acid-induced fluorescence in meningiomas. ( Coluccia, D; Cordovi, S; Fandino, J; Fujioka, M; Landolt, H; Muroi, C, 2010)
"It has a tendency to metastasise to regional or distant sites after incomplete treatment."1.34Photodynamic therapy suppresses the migration and invasion of head and neck cancer cells in vitro. ( Chen, CT; Lou, PJ; Wang, CP; Yang, TH, 2007)
"Head and neck cancer is highly invasive."1.34Photodynamic therapy suppresses the migration and invasion of head and neck cancer cells in vitro. ( Chen, CT; Lou, PJ; Wang, CP; Yang, TH, 2007)
"High-grade gliomas are characterized by rapid proliferation, angiogenesis, and invasive growth."1.33Effects of ALA-mediated photodynamic therapy on the invasiveness of human glioma cells. ( Hirschberg, H; Krasieva, T; Madsen, SJ; Sun, CH, 2006)
"The prognosis of superficial bladder cancer in terms of local recurrence and transformation into invasive cancer is related to the multiplicity of tumor sites and the concomitant presence of "flat" tumours, such as dysplasia and carcinoma in situ."1.30[The clinical value of fluorescence cystoscopy in the detection of superficial transitional epithelial cell carcinoma of the bladder]. ( Forrer, M; Graber, P; Guillou, L; Jichlinski, P; Leisinger, HJ; Mizeret, J; Schmidlin, F; Van den Bergh, H; Wagniéres, G, 1997)

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (2.94)18.2507
2000's15 (22.06)29.6817
2010's44 (64.71)24.3611
2020's7 (10.29)2.80

Authors

AuthorsStudies
Fukuhara, H4
Inoue, K5
Yamamoto, S1
Lai, HW1
Karashima, T1
Kurabayashi, A2
Furihata, M2
Kobayashi, K1
Matsuyama, H2
Oka, S1
Nakamura, K1
Misumi, T1
Hiroyoshi, T1
Ito, H1
Isoyama, N1
Hirata, H1
Matsumoto, H1
Shiraishi, K1
Kibbi, N1
Zhang, Y1
Leffell, DJ1
Christensen, SR1
Williams, SB1
Gavaghan, MB1
Fernandez, A1
Daneshmand, S3
Kamat, AM3
Sugino, Y1
Nishikawa, K1
Kato, M2
Sasaki, T1
Masui, S1
Yoshio, Y1
Kanda, H1
Sugimura, Y2
Inoue, T1
Jacqmin, D5
Jichlinski, P6
Molinier, L2
de la Taille, A1
Irani, J1
Malavaud, B2
Gallagher, KM1
Gray, K1
Anderson, CH1
Lee, H1
Stewart, S1
Donat, R1
Mariappan, P2
Yagi, R1
Kawabata, S1
Ikeda, N1
Nonoguchi, N1
Furuse, M1
Katayama, Y2
Kajimoto, Y2
Kuroiwa, T2
Belykh, E1
Miller, EJ1
Hu, D1
Martirosyan, NL1
Woolf, EC1
Scheck, AC1
Byvaltsev, VA1
Nakaji, P1
Nelson, LY1
Seibel, EJ1
Preul, MC1
Rioli, DI1
Samimi, M1
Beneton, N1
Hainaut, E1
Martin, L1
Misery, L1
Quereux, G1
Safar, R1
Alkhars, A1
Tallegas, M1
Korsaga-Some, N1
Machet, L1
Lotan, Y1
Bivalacqua, TJ1
Downs, T1
Huang, W1
Jones, J1
Konety, B1
Malmström, PU2
McKiernan, J1
O'Donnell, M1
Patel, S1
Pohar, K1
Resnick, M1
Sankin, A1
Smith, A1
Steinberg, G1
Trabulsi, E1
Woods, M1
Renninger, M1
Fahmy, O1
Schubert, T1
Schmid, MA1
Hassan, F1
Stenzl, A7
Gakis, G1
Konecki, T1
Kutwin, P1
Łowicki, R1
Juszczak, AB1
Jabłonowski, Z1
Cage, TA1
Pekmezci, M1
Prados, M1
Berger, MS1
Ferré, A1
Cordonnier, C1
Demailly, M1
Hakami, F1
Sevestre, H1
Saint, F1
Roozeboom, MH1
Aardoom, MA1
Nelemans, PJ1
Thissen, MR1
Kelleners-Smeets, NW1
Kuijpers, DI1
Mosterd, K2
Burger, M4
Grossman, HB3
Droller, M1
Schmidbauer, J1
Hermann, G1
Drăgoescu, O2
Ray, E1
Fradet, Y2
Karl, A3
Burgués, JP1
Witjes, JA6
Jocham, D4
Lippert, J1
Smucler, R1
Vlk, M1
Rink, M1
Babjuk, M3
Catto, JW1
Shariat, SF1
Stepp, H2
Zaak, D4
Namikawa, T1
Uemura, S1
Shiga, M1
Maeda, H1
Kitagawa, H1
Kobayashi, M1
Shuin, T3
Hanazaki, K1
Gkritsios, P1
Hatzimouratidis, K1
Kazantzidis, S1
Dimitriadis, G1
Ioannidis, E1
Katsikas, V1
Roder, C1
Bisdas, S1
Ebner, FH1
Honegger, J1
Naegele, T1
Ernemann, U1
Tatagiba, M1
Gilaberte, Y1
Milla, L1
Salazar, N1
Vera-Alvarez, J1
Kourani, O1
Damian, A1
Rivarola, V1
Roca, MJ1
Espada, J1
González, S1
Juarranz, A1
Fargnoli, MC1
Kostaki, D1
Piccioni, A1
Di Stefani, A1
Peris, K1
Gontero, P1
Kruck, S1
Palou Redorta, J1
van Velthoven, R1
Schuckman, AK1
Bochner, BH1
Cookson, MS1
Downs, TM1
Gomella, LG1
Konety, BR1
Lee, CT1
Pohar, KS1
Pruthi, RS1
Resnick, MJ1
Smith, ND1
Schoenberg, MP1
Steinberg, GD1
Rouprêt, M1
Leleu, H1
Blachier, M1
Marteau, F1
Li, PT1
Tsai, YJ1
Lee, MJ1
Chen, CT3
Fujimoto, K1
Hirao, Y1
Watanabe, H2
Ozono, S1
Oyama, M1
Ueno, M1
Shiina, H1
Mimata, H1
Azuma, H1
Nagase, Y1
Matsubara, A1
Ito, YM1
Kessels, J1
Hendriks, J1
Nelemans, P1
Kelleners-Smeets, N1
Bach, T1
Bastian, PJ1
Blana, A1
Kaminsky, A1
Keller, S1
Knoll, T1
Lang, C1
Promnitz, S1
Ubrig, B1
Keller, T1
Qvick, B1
Rolevich, AI1
Zhegalik, AG1
Mokhort, AA1
Minich, AA1
Vasilevich, VY1
Polyakov, SL1
Krasny, SA1
Sukonko, OG1
Filonenko, EV1
Kaprin, AD1
Alekseev, BY1
Apolikhin, OI1
Slovokhodov, EK1
Ivanova-Radkevich, VI1
Urlova, AN1
Fahey, JM1
Girotti, AW1
Choi, SH1
Kim, KH1
Song, KH1
Madsen, SJ2
Mathews, MS1
Angell-Petersen, E1
Sun, CH2
Vo, V1
Sanchez, R1
Hirschberg, H2
Tsai, T1
Ji, HT1
Chiang, PC1
Chou, RH1
Chang, WS1
Dindyal, S1
Nitkunan, T1
Bunce, CJ1
Draga, RO1
Bosch, JL1
Grimbergen, MC1
Kausch, I2
Sommerauer, M2
Montorsi, F3
Ziegler, A2
Vonthein, R2
Bunce, C1
Ayres, BE1
Griffiths, TR1
Mostafid, H1
Kelly, J1
Persad, R1
Kockelbergh, R1
Redorta, JP1
Sofras, F1
Riedl, C1
Conti, G1
Arentsen, HC1
Mostafid, AH1
Park, JH1
Moon, YH1
Kim, DJ1
Kim, SA1
Lee, JB1
Ahn, SG1
Yoon, JH1
Coluccia, D1
Fandino, J1
Fujioka, M1
Cordovi, S1
Muroi, C1
Landolt, H1
Li, Q1
Gao, T1
Long, HA1
Ujiie, H1
Hefti, M1
Tomescu, P1
Pănuş, A1
Enache, M1
Maria, C1
Stoica, L1
Pleşea, IE1
Shimamoto, T1
Kamada, M1
Iiyama, T1
Miyamura, M1
Tanimura, M1
Kishi, K1
Fujiwara, Y1
Yano, M1
Inoue, M1
Miyashiro, I1
Motoori, M1
Shingai, T1
Gotoh, K1
Takahashi, H1
Noura, S1
Yamada, T1
Ohue, M1
Ohigashi, H1
Ishikawa, O1
Mynderse, LA1
Kriegmair, M1
Soloway, MS1
Akoel, KM1
Welfel, J1
Gottwald, L1
Suzin, J1
Gamarra, F1
Lingk, P1
Marmarova, A1
Edelmann, M1
Hautmann, H1
Baumgartner, R1
Huber, RM1
Schleier, P1
Hyckel, P1
Berndt, A1
Bode, HP1
Albrecht, V1
Hindermann, W1
Kosmehl, H1
Zenk, W1
Schumann, D1
Arens, C1
Utsuki, S1
Oka, H1
Sato, S1
Suzuki, S1
Shimizu, S1
Tanaka, S1
Fujii, K1
Au, CM1
Luk, SK1
Jackson, CJ1
Ng, HK1
Yow, CM1
To, SS1
Yang, TH1
Wang, CP1
Lou, PJ1
Krasieva, T1
Ishihara, R1
Watanabe, T1
Yoshino, A1
Fukushima, T1
Sakatani, K1
Miyatake, S1
Ichioka, T1
Miyashita, M1
Tanaka, H1
Tsuji, M1
Denzinger, S1
Hartmann, A1
Hofstaedter, F1
Knuechel, R1
Wild, PJ1
Stief, C1
Wieland, WF1
Stoehr, R1
Lui, H1
Salasche, S1
Kollias, N1
Wimberly, J1
Flotte, T1
McLean, D1
Anderson, RR1
Wagniéres, G1
Forrer, M1
Mizeret, J1
Guillou, L1
Schmidlin, F1
Graber, P1
Van den Bergh, H1
Leisinger, HJ1
Kitada, M1
Ohsaki, Y1
Yasuda, S1
Abe, M1
Takahashi, N1
Okazaki, S1
Ishibashi, K1
Hayashi, S1
Cornelius, JF1
Eismann, L1
Ebbert, L1
Senger, B1
Petridis, AK1
Kamp, MA1
Sorg, RV1
Steiger, HJ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Safety Analysis and Oncological Outcomes in Endoscopic Bladder Tumor Resection With Laser Holmium Compared With Transurethral Resection: a Prospective and Randomized Study[NCT05833997]100 participants (Anticipated)Interventional2020-12-10Recruiting
A Randomised Trial Comparing Methyl Aminolaevulinate Photodynamic Therapy With and Without Ablative Fractional Laser Treatment in Patients With Microinvasive Squamous Cell Carcinoma: Results From a 24-month Follow-up[NCT02666534]Phase 145 participants (Actual)Interventional2012-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

12 reviews available for aminolevulinic acid and Invasiveness, Neoplasm

ArticleYear
Blue light flexible cystoscopy with hexaminolevulinate in non-muscle-invasive bladder cancer: review of the clinical evidence and consensus statement on optimal use in the USA - update 2018.
    Nature reviews. Urology, 2019, Volume: 16, Issue:6

    Topics: Aminolevulinic Acid; Consensus Development Conferences as Topic; Cystectomy; Cystoscopes; Cystoscopy

2019
Hexaminolevulinate in the Management of Nonmuscle Invasive Bladder Cancer: A Meta-Analysis.
    Photobiomodulation, photomedicine, and laser surgery, 2019, Volume: 37, Issue:9

    Topics: Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Humans; Neoplasm Invasiveness; Photosensitizing

2019
Photodynamic diagnosis of non-muscle-invasive bladder cancer with hexaminolevulinate cystoscopy: a meta-analysis of detection and recurrence based on raw data.
    European urology, 2013, Volume: 64, Issue:5

    Topics: Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Humans; Kaplan-Meier Estimate; Neoplasm Invasive

2013
Hexyl aminolevulinate-guided fluorescence cystoscopy in the diagnosis and follow-up of patients with non-muscle-invasive bladder cancer: a critical review of the current literature.
    European urology, 2013, Volume: 64, Issue:4

    Topics: Aminolevulinic Acid; Cost-Benefit Analysis; Cystectomy; Cystoscopy; Disease-Free Survival; Health Ca

2013
Photodynamic therapy for the treatment of microinvasive squamous cell carcinoma of the lower lip: a case report.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2015, Volume: 150, Issue:3

    Topics: Aged; Aminolevulinic Acid; Carcinoma, Squamous Cell; Cheilitis; Dermoscopy; Humans; Lip Neoplasms; M

2015
Clinical and cost effectiveness of hexaminolevulinate-guided blue-light cystoscopy: evidence review and updated expert recommendations.
    European urology, 2014, Volume: 66, Issue:5

    Topics: Aminolevulinic Acid; Cost-Benefit Analysis; Cystectomy; Cystoscopy; Disease Progression; Disease-Fre

2014
Hexaminolevulinate blue-light cystoscopy in non-muscle-invasive bladder cancer: review of the clinical evidence and consensus statement on appropriate use in the USA.
    Nature reviews. Urology, 2014, Volume: 11, Issue:10

    Topics: Aminolevulinic Acid; Carcinoma, Transitional Cell; Consensus; Cystoscopy; Humans; Neoplasm Invasiven

2014
The economic benefit of photodynamic diagnosis in non-muscle invasive bladder cancer.
    Photodiagnosis and photodynamic therapy, 2008, Volume: 5, Issue:2

    Topics: Aminolevulinic Acid; Carcinoma, Transitional Cell; Fluorescence; Humans; Neoplasm Invasiveness; Phot

2008
Photodynamic diagnosis in non-muscle-invasive bladder cancer: a systematic review and cumulative analysis of prospective studies.
    European urology, 2010, Volume: 57, Issue:4

    Topics: Aminolevulinic Acid; Cystectomy; Cystoscopy; Disease-Free Survival; Evidence-Based Medicine; Humans;

2010
The role of hexylaminolaevulinate in the diagnosis and follow-up of non-muscle-invasive bladder cancer.
    BJU international, 2010, Volume: 105 Suppl 2

    Topics: Aminolevulinic Acid; Cystoscopy; Humans; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Photosen

2010
Hexaminolevulinate-guided fluorescence cystoscopy in the diagnosis and follow-up of patients with non-muscle-invasive bladder cancer: review of the evidence and recommendations.
    European urology, 2010, Volume: 57, Issue:4

    Topics: Aminolevulinic Acid; Cystectomy; Cystoscopy; Disease-Free Survival; Evidence-Based Medicine; Humans;

2010
[Fluorescence diagnosis in patients with non-muscle invasive bladder cancer: results of a metaanalysis].
    Aktuelle Urologie, 2010, Volume: 41, Issue:3

    Topics: Aminolevulinic Acid; Cystoscopy; Disease-Free Survival; Fluorescence; Humans; Neoplasm Invasiveness;

2010

Trials

8 trials available for aminolevulinic acid and Invasiveness, Neoplasm

ArticleYear
Fractionated 5-aminolevulinic acid photodynamic therapy after partial debulking versus surgical excision for nodular basal cell carcinoma: a randomized controlled trial with at least 5-year follow-up.
    Journal of the American Academy of Dermatology, 2013, Volume: 69, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Combined Modality Therap

2013
Hexaminolevulinate-guided transurethral resection of non-muscle-invasive bladder cancer does not reduce the recurrence rates after a 2-year follow-up: a prospective randomized trial.
    International urology and nephrology, 2014, Volume: 46, Issue:5

    Topics: Aged; Aminolevulinic Acid; Color; Contrast Media; Cystoscopy; Disease-Free Survival; False Positive

2014
The clinical trial on the safety and effectiveness of the photodynamic diagnosis of non-muscle-invasive bladder cancer using fluorescent light-guided cystoscopy after oral administration of 5-aminolevulinic acid (5-ALA).
    Photodiagnosis and photodynamic therapy, 2016, Volume: 13

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Contrast Media; Cystoscop

2016
Results of a prospective randomized study assessing the efficacy of fluorescent cystoscopy-assisted transurethral resection and single instillation of doxorubicin in patients with non-muscle-invasive bladder cancer.
    World journal of urology, 2017, Volume: 35, Issue:5

    Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Antibiotics, Anti

2017
5-Aminolevulinic acid in intraoperative photodynamic therapy of bladder cancer (results of multicenter trial).
    Photodiagnosis and photodynamic therapy, 2016, Volume: 16

    Topics: Adult; Aged; Aminolevulinic Acid; Combined Modality Therapy; Cystectomy; Female; Humans; Male; Middl

2016
Effect of Methyl Aminolevulinate Photodynamic Therapy With and Without Ablative Fractional Laser Treatment in Patients With Microinvasive Squamous Cell Carcinoma: A Randomized Clinical Trial.
    JAMA dermatology, 2017, 03-01, Volume: 153, Issue:3

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Squamous Cell; Female; Humans; Lasers, Soli

2017
Photodynamic diagnosis of non-muscle invasive bladder cancer using hexaminolevulinic acid.
    Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie, 2011, Volume: 52, Issue:1

    Topics: Aminolevulinic Acid; Cystoscopy; Female; Humans; Kaplan-Meier Estimate; Light; Male; Middle Aged; Mu

2011
Long-term decrease in bladder cancer recurrence with hexaminolevulinate enabled fluorescence cystoscopy.
    The Journal of urology, 2012, Volume: 188, Issue:1

    Topics: Aged; Aminolevulinic Acid; Canada; Carbon Radioisotopes; Cystoscopy; Diagnosis, Differential; Europe

2012

Other Studies

48 other studies available for aminolevulinic acid and Invasiveness, Neoplasm

ArticleYear
[Ⅰ. Diagnosis and Therapy for Non-Muscle Invasive Bladder Cancer Using Photodynamic Technique].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2022, Volume: 49, Issue:1

    Topics: Aminolevulinic Acid; Humans; Neoplasm Invasiveness; Photochemotherapy; Photosensitizing Agents; Urin

2022
Real-world experience with 5-aminolevulinic acid for photodynamic diagnosis of bladder cancer (2nd report): Reduced bladder recurrence after PDD-TURBT.
    Photodiagnosis and photodynamic therapy, 2022, Volume: 38

    Topics: Aminolevulinic Acid; Cystoscopy; Humans; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Photoche

2022
Risks and benefits of transurethral resection of the bladder tumor using photodynamic diagnosis with oral 5-aminolevulinic acid hydrochloride according to age and history of recurrence in patients with non-muscle invasive bladder cancer.
    Photodiagnosis and photodynamic therapy, 2023, Volume: 41

    Topics: Aminolevulinic Acid; Cystectomy; Humans; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Non-Musc

2023
Photodynamic therapy for cutaneous squamous cell carcinoma in situ: Impact of anatomic location, tumor diameter, and incubation time on effectiveness.
    Journal of the American Academy of Dermatology, 2020, Volume: 82, Issue:5

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Analysis of Variance; Biopsy, Needle; Carcinoma in Sit

2020
Macro and microeconomics of blue light cystoscopy with CYSVIEW® in non-muscle invasive bladder cancer.
    Urologic oncology, 2022, Volume: 40, Issue:1

    Topics: Aminolevulinic Acid; Cystoscopy; Humans; Neoplasm Invasiveness; Population Surveillance; Urinary Bla

2022
[Initial Experience of Photodynamic Diagnosis-Assisted Transurethral Resection of Bladder Tumor (PDD-TURBT)].
    Hinyokika kiyo. Acta urologica Japonica, 2021, Volume: 67, Issue:7

    Topics: Aged; Aminolevulinic Acid; Cystectomy; Cystoscopy; Humans; Neoplasm Invasiveness; Neoplasm Recurrenc

2021
Observational Studies Requested by European Health Authorities: Governmental Interference or an Enhancement of Everyday Urological Practice? The Hexvix® Observational Patients Evaluation Study as an Example of What to Expect.
    Urologia internationalis, 2017, Volume: 99, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cystectomy; Cystoscopy; Disease Progression; Di

2017
'Real-life experience': recurrence rate at 3 years with Hexvix
    World journal of urology, 2017, Volume: 35, Issue:12

    Topics: Administration, Intravesical; Aged; Aminolevulinic Acid; Cystectomy; Cystoscopy; Female; Humans; Kap

2017
Intraoperative 5-aminolevulinic acid-induced photodynamic diagnosis of metastatic brain tumors with histopathological analysis.
    World journal of surgical oncology, 2017, Sep-29, Volume: 15, Issue:1

    Topics: Adult; Aged; Aminolevulinic Acid; Brain; Brain Neoplasms; Female; Fluorescence; Humans; Intraoperati

2017
Scanning Fiber Endoscope Improves Detection of 5-Aminolevulinic Acid-Induced Protoporphyrin IX Fluorescence at the Boundary of Infiltrative Glioma.
    World neurosurgery, 2018, Volume: 113

    Topics: Administration, Oral; Aminolevulinic Acid; Animals; Biotransformation; Brain Neoplasms; Cell Line, T

2018
Efficacy and tolerance of photodynamic therapy for vulvar Paget's disease: a multicentric retrospective study.
    European journal of dermatology : EJD, 2018, Jun-01, Volume: 28, Issue:3

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Follow-Up Studies; Humans; Middle Aged; Neopla

2018
Successful Treatment for Extensive Bowen's Disease using Daylight-mediated Photodynamic Therapy.
    Acta dermato-venereologica, 2019, Jun-01, Volume: 99, Issue:7

    Topics: Aged, 80 and over; Aminolevulinic Acid; Biopsy, Needle; Bowen's Disease; Follow-Up Studies; Humans;

2019
The prognostic impact of hexaminolevulinate-based bladder tumor resection in patients with primary non-muscle invasive bladder cancer treated with radical cystectomy.
    World journal of urology, 2020, Volume: 38, Issue:2

    Topics: Administration, Intravesical; Aged; Aminolevulinic Acid; Antineoplastic Agents; Cystectomy; Female;

2020
Subependymal spread of recurrent glioblastoma detected with the intraoperative use of 5-aminolevulinic acid: case report.
    Journal of neurosurgery, 2013, Volume: 118, Issue:6

    Topics: Aminolevulinic Acid; Diagnosis, Differential; Glioblastoma; Glioma, Subependymal; Humans; Intraopera

2013
[Bladder tumor targeting by Hexvix(®) fluorescence: 4 years results after prospective monocentric evaluation].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2013, Volume: 23, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cystoscopy; Female; Fluorescence; France; Human

2013
Fractional carbon dioxide laser improves nodular basal cell carcinoma treatment with photodynamic therapy with methyl 5-aminolevulinate.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2013, Volume: 39, Issue:8

    Topics: Aminolevulinic Acid; Carcinoma, Basal Cell; Combined Modality Therapy; Female; Humans; Lasers, Gas;

2013
Photodynamic diagnosis using 5-aminolevulinic acid during gastrectomy for gastric cancer.
    Journal of surgical oncology, 2014, Volume: 109, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Feasibility Studies; Female; Fluorescence; Gast

2014
Maximizing the extent of resection and survival benefit of patients in glioblastoma surgery: high-field iMRI versus conventional and 5-ALA-assisted surgery.
    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2014, Volume: 40, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Brain Neoplasms; Cohort Studies; Disease-Free S

2014
Cellular intrinsic factors involved in the resistance of squamous cell carcinoma to photodynamic therapy.
    The Journal of investigative dermatology, 2014, Volume: 134, Issue:9

    Topics: Aged, 80 and over; Aminolevulinic Acid; Animals; Biopsy; Cell Line, Tumor; Comparative Genomic Hybri

2014
[Cost-effectiveness of transurethral resection of the bladder with blue light in patients with non muscle invasive bladder cancer in France].
    Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2015, Volume: 25, Issue:5

    Topics: Administration, Intravesical; Aged; Aminolevulinic Acid; Carcinoma, Transitional Cell; Cost Savings;

2015
Increased Histone Deacetylase Activity Involved in the Suppressed Invasion of Cancer Cells Survived from ALA-Mediated Photodynamic Treatment.
    International journal of molecular sciences, 2015, Oct-10, Volume: 16, Issue:10

    Topics: Acetylation; Aminolevulinic Acid; Azacitidine; Cell Line, Tumor; Cell Movement; Chromatin Immunoprec

2015
Two-fold illumination in topical 5-aminolevulinic acid (ALA)-mediated photodynamic therapy (PDT) for superficial basal cell carcinoma (sBCC): A retrospective case series and cohort study.
    Journal of the American Academy of Dermatology, 2016, Volume: 74, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Cohort Studies; Confiden

2016
Optimised photodynamic diagnosis for transurethral resection of the bladder (TURB) in German clinical practice: results of the noninterventional study OPTIC III.
    World journal of urology, 2017, Volume: 35, Issue:5

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell; Cysto

2017
Nitric oxide-mediated resistance to photodynamic therapy in a human breast tumor xenograft model: Improved outcome with NOS2 inhibitors.
    Nitric oxide : biology and chemistry, 2017, Jan-30, Volume: 62

    Topics: Amidines; Aminolevulinic Acid; Animals; Apoptosis; Apoptosis Regulatory Proteins; Benzoates; Benzyla

2017
Motexafin gadolinium enhances the efficacy of aminolevulinic acid mediated-photodynamic therapy in human glioma spheroids.
    Journal of neuro-oncology, 2009, Volume: 91, Issue:2

    Topics: Aminolevulinic Acid; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Dose-Response Relations

2009
ALA-PDT results in phenotypic changes and decreased cellular invasion in surviving cancer cells.
    Lasers in surgery and medicine, 2009, Volume: 41, Issue:4

    Topics: Adenocarcinoma; Aminolevulinic Acid; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Down-Regulat

2009
Noninvasive transitional cell carcinoma is associated with a high occurrence of false positives in photodynamic diagnosis.
    European urology, 2009, Volume: 56, Issue:6

    Topics: Aminolevulinic Acid; Carcinoma, Transitional Cell; Cystoscopy; False Positive Reactions; Female; Flu

2009
Photodynamic therapy with hexenyl ester of 5-aminolevulinic acid induces necrotic cell death in salivary gland adenocarcinoma cells.
    Oncology reports, 2010, Volume: 24, Issue:1

    Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; C

2010
Intraoperative 5-aminolevulinic-acid-induced fluorescence in meningiomas.
    Acta neurochirurgica, 2010, Volume: 152, Issue:10

    Topics: Adult; Aged; Aminolevulinic Acid; Female; Fluorescence; Humans; Male; Meningeal Neoplasms; Meningiom

2010
Clearance of a thick invasive squamous cell carcinoma after multiple treatments with topical photodynamic therapy.
    Photomedicine and laser surgery, 2010, Volume: 28, Issue:5

    Topics: Administration, Topical; Aminolevulinic Acid; Biopsy, Needle; Carcinoma, Squamous Cell; Female; Foll

2010
Comment concerning: Intraoperative 5-aminolevulinic-acid-induced fluorescence in meningiomas, Acta Neurochir DOl 1O.1007/s00701-010-0708-4, Intratumoral heterogeneity and fluorescence intensity in meningioma after 5-ALA pretreatment.
    Acta neurochirurgica, 2011, Volume: 153, Issue:4

    Topics: Aminolevulinic Acid; Chromosome Aberrations; Fluorescence; Genetic Heterogeneity; Humans; Intraopera

2011
Comparison between intravesical and oral administration of 5-aminolevulinic acid in the clinical benefit of photodynamic diagnosis for nonmuscle invasive bladder cancer.
    Cancer, 2012, Feb-15, Volume: 118, Issue:4

    Topics: Administration, Intravesical; Administration, Oral; Adult; Aged; Aged, 80 and over; Aminolevulinic A

2012
Staging laparoscopy using ALA-mediated photodynamic diagnosis improves the detection of peritoneal metastases in advanced gastric cancer.
    Journal of surgical oncology, 2012, Sep-01, Volume: 106, Issue:3

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Animals; Disease Models, Animal; Female; Fluorescence;

2012
[Photodynamic diagnosis of vulvar precancerous conditions and invasive cancers using 5-aminolevulinic acid].
    Ginekologia polska, 2003, Volume: 74, Issue:9

    Topics: Aminolevulinic Acid; Carcinoma in Situ; Diagnostic Techniques, Obstetrical and Gynecological; Female

2003
5-Aminolevulinic acid-induced fluorescence in bronchial tumours: dependency on the patterns of tumour invasion.
    Journal of photochemistry and photobiology. B, Biology, 2004, Jan-23, Volume: 73, Issue:1-2

    Topics: Aminolevulinic Acid; Bronchial Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Fluoresc

2004
Photodynamic therapy of virus-associated epithelial tumours of the face in organ transplant recipients.
    Journal of cancer research and clinical oncology, 2004, Volume: 130, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Facial Neoplasms; Humans; Keratosis

2004
[Early diagnosis of laryngeal cancer].
    Laryngo- rhino- otologie, 2004, Volume: 83, Issue:11

    Topics: Aminolevulinic Acid; Diagnosis, Differential; Early Diagnosis; Fluorescence; Humans; Laryngeal Neopl

2004
Possibility of using laser spectroscopy for the intraoperative detection of nonfluorescing brain tumors and the boundaries of brain tumor infiltrates. Technical note.
    Journal of neurosurgery, 2006, Volume: 104, Issue:4

    Topics: Adult; Aminolevulinic Acid; Astrocytoma; Brain; Brain Neoplasms; Female; Humans; Lasers; Male; Middl

2006
Differential effects of photofrin, 5-aminolevulinic acid and calphostin C on glioma cells.
    Journal of photochemistry and photobiology. B, Biology, 2006, Nov-01, Volume: 85, Issue:2

    Topics: Aminolevulinic Acid; Cell Adhesion; Cell Adhesion Molecules; Cell Line, Tumor; Cell Proliferation; D

2006
Photodynamic therapy suppresses the migration and invasion of head and neck cancer cells in vitro.
    Oral oncology, 2007, Volume: 43, Issue:4

    Topics: Aminolevulinic Acid; Cell Line, Tumor; Cell Movement; Cell Survival; Collagen; Drug Combinations; Ex

2007
Effects of ALA-mediated photodynamic therapy on the invasiveness of human glioma cells.
    Lasers in surgery and medicine, 2006, Volume: 38, Issue:10

    Topics: Aminolevulinic Acid; Brain Neoplasms; Cell Physiological Phenomena; Dose-Response Relationship, Drug

2006
Quantitative spectroscopic analysis of 5-aminolevulinic acid-induced protoporphyrin IX fluorescence intensity in diffusely infiltrating astrocytomas.
    Neurologia medico-chirurgica, 2007, Volume: 47, Issue:2

    Topics: Aged; Aminolevulinic Acid; Astrocytoma; Brain Neoplasms; Female; Humans; Male; Middle Aged; Neoplasm

2007
Use of 5-aminolevulinic acid in fluorescence-guided resection of meningioma with high risk of recurrence. Case report.
    Journal of neurosurgery, 2007, Volume: 106, Issue:6

    Topics: Aged; Aminolevulinic Acid; Craniotomy; Female; Fluorescence; Humans; Magnetic Resonance Imaging; Men

2007
[Interdisciplinary networking for clinical and molecular questions in non-muscle invasive urothelial carcinoma of the bladder].
    Der Urologe. Ausg. A, 2007, Volume: 46, Issue:9

    Topics: Aminolevulinic Acid; Biomarkers, Tumor; Carcinoma, Transitional Cell; Cooperative Behavior; Cystosco

2007
Photodynamic therapy of nonmelanoma skin cancer with topical aminolevulinic acid: a clinical and histologic study.
    Archives of dermatology, 1995, Volume: 131, Issue:6

    Topics: Administration, Cutaneous; Aged; Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Basal Cell; Carc

1995
[The clinical value of fluorescence cystoscopy in the detection of superficial transitional epithelial cell carcinoma of the bladder].
    Annales d'urologie, 1997, Volume: 31, Issue:1

    Topics: Administration, Intravesical; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Carci

1997
Photodynamic diagnosis of visceral pleural invasion of lung cancer with a combination of 5-aminolevulinic acid and autofluorescence observation systems.
    Photodiagnosis and photodynamic therapy, 2017, Volume: 20

    Topics: Aminolevulinic Acid; Female; Humans; Levulinic Acids; Lung Neoplasms; Male; Neoplasm Invasiveness; O

2017
5-Aminolevulinic acid-based photodynamic therapy of chordoma: In vitro experiments on a human tumor cell line.
    Photodiagnosis and photodynamic therapy, 2017, Volume: 20

    Topics: Aminolevulinic Acid; Cell Line, Tumor; Chordoma; Dose-Response Relationship, Drug; Humans; Levulinic

2017