aminolevulinic acid has been researched along with Inflammation in 22 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 72-year-old woman suffering from multiple actinic keratosis (AK) complicating steroid-induced rosacea received 5-aminolevulinic acid-photodynamic therapy (ALA-PDT) in our outpatient clinic." | 8.12 | Inflammation burst after 5-aminolevulinic acid-photodynamic therapy for the treatment of actinic keratosis complicating rosacea: A case report. ( Cao, Y; Hu, C; Liu, P; Liu, X; Wang, P; Wang, X; Yang, X; Zhang, L, 2022) |
| "Scleroderma or systemic sclerosis (SSc) is a clinically heterogeneous rheumatological autoimmune disease affecting the skin, internal organs and blood vessels." | 5.48 | Combination of 5-aminolevulinic acid and iron prevents skin fibrosis in murine sclerodermatous graft-versus-host disease. ( Fujino, M; Ito, H; Li, XK; Liu, C; Nakajima, M; Takahashi, K; Tanaka, T; Wang, J; Yang, X; Zhu, P; Zhuang, J; Zou, H, 2018) |
| "A 72-year-old woman suffering from multiple actinic keratosis (AK) complicating steroid-induced rosacea received 5-aminolevulinic acid-photodynamic therapy (ALA-PDT) in our outpatient clinic." | 4.12 | Inflammation burst after 5-aminolevulinic acid-photodynamic therapy for the treatment of actinic keratosis complicating rosacea: A case report. ( Cao, Y; Hu, C; Liu, P; Liu, X; Wang, P; Wang, X; Yang, X; Zhang, L, 2022) |
| "To study the differential effects of bacillus Calmette-Guérin (BCG) and mitomycin C (MMC) intravesical therapy on the false-positive rate of PDD of bladder cancer." | 3.76 | Photodynamic diagnosis (5-aminolevulinic acid) of transitional cell carcinoma after bacillus Calmette-Guérin immunotherapy and mitomycin C intravesical therapy. ( Bosch, JL; Draga, RO; Grimbergen, MC; Jonges, TN; Kok, ET; van Swol, CF, 2010) |
| "Acute skin inflammation occurs following topical aminolevulinic acid-photodynamic therapy (ALA-PDT), but its nature and mediation are ill defined." | 3.73 | Histamine is released following aminolevulinic acid-photodynamic therapy of human skin and mediates an aminolevulinic acid dose-related immediate inflammatory response. ( Brooke, RC; Church, MK; Clough, GF; Friedmann, PS; Rhodes, LE; Sidhu, MK; Sinha, A; Watson, RE, 2006) |
| "5-Aminolevulinic acid (5-ALA) is a naturally occurring amino acid and precursor of heme and protoporphyrin IX (PpIX)." | 2.53 | 5-Aminolevulinic acid regulates the inflammatory response and alloimmune reaction. ( Fujino, M; Ito, H; Li, XK; Nishio, Y; Tanaka, T, 2016) |
| "Severe acne vulgaris is a common chronic inflammatory skin disease worldwide." | 1.91 | ALA-PDT augments intense inflammation in the treatment of acne vulgaris by COX2/TREM1 mediated M1 macrophage polarization. ( Liu, P; Liu, X; Wang, P; Wang, X; Wu, Y; Xu, D; Yan, G; Zeng, Q; Zhang, G; Zhang, H; Zhang, L, 2023) |
| "5-aminolevulinic acid (ALA) is a natural amino acid and a product of the first heme synthesis pathway in mitochondria." | 1.72 | The effect of 5-aminolevulinic acid on canine peripheral blood mononuclear cells. ( Igase, M; Iwatani, N; Mizukami, Y; Mizuno, T; Sakai, A; Watanabe, K, 2022) |
| "Scleroderma or systemic sclerosis (SSc) is a clinically heterogeneous rheumatological autoimmune disease affecting the skin, internal organs and blood vessels." | 1.48 | Combination of 5-aminolevulinic acid and iron prevents skin fibrosis in murine sclerodermatous graft-versus-host disease. ( Fujino, M; Ito, H; Li, XK; Liu, C; Nakajima, M; Takahashi, K; Tanaka, T; Wang, J; Yang, X; Zhu, P; Zhuang, J; Zou, H, 2018) |
| "The inflamed atherosclerotic plaque in the common carotid artery was produced by combination of balloon denudation injury and high cholesterol diet." | 1.37 | Detection and photodynamic therapy of inflamed atherosclerotic plaques in the carotid artery of rabbits. ( Cao, W; Cheng, J; Guo, Y; Li, Q; Li, Y; Li, Z; Liang, H; Peng, C; Sun, X; Tian, Y; Tian, Z; Wang, F; Yang, L; Zhang, Z, 2011) |
| " In 13 healthy volunteers, we assessed the time course and dose-response of the acute cutaneous response(s) to ALA-PDT, the impact of H(1) antihistamine blockade, and measured dermal histamine release." | 1.33 | Histamine is released following aminolevulinic acid-photodynamic therapy of human skin and mediates an aminolevulinic acid dose-related immediate inflammatory response. ( Brooke, RC; Church, MK; Clough, GF; Friedmann, PS; Rhodes, LE; Sidhu, MK; Sinha, A; Watson, RE, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (18.18) | 29.6817 |
| 2010's | 12 (54.55) | 24.3611 |
| 2020's | 6 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Saunders, MJ | 1 |
| Edwards, BS | 1 |
| Zhu, J | 1 |
| Sklar, LA | 1 |
| Graves, SW | 1 |
| Li, L | 1 |
| Yang, Y | 1 |
| Yang, Z | 1 |
| Zheng, M | 1 |
| Luo, G | 1 |
| He, W | 1 |
| Yin, R | 1 |
| Liu, P | 2 |
| Liu, X | 2 |
| Wang, P | 2 |
| Zhang, L | 2 |
| Hu, C | 1 |
| Yang, X | 2 |
| Cao, Y | 1 |
| Wang, X | 2 |
| Igase, M | 1 |
| Iwatani, N | 1 |
| Sakai, A | 1 |
| Watanabe, K | 1 |
| Mizukami, Y | 1 |
| Mizuno, T | 1 |
| Wulf, HC | 2 |
| Heerfordt, IM | 1 |
| Yan, G | 1 |
| Zhang, H | 1 |
| Xu, D | 1 |
| Wu, Y | 1 |
| Zhang, G | 1 |
| Zeng, Q | 1 |
| Otaka, Y | 1 |
| Kanai, K | 1 |
| Mori, A | 1 |
| Okada, D | 1 |
| Nagai, N | 1 |
| Yamashita, Y | 1 |
| Ichikawa, Y | 1 |
| Tajima, K | 1 |
| Suárez-Valladares, MJ | 1 |
| Calleja-Antolín, SM | 1 |
| García Ruíz de Morales, JM | 1 |
| Rodríguez Prieto, MA | 1 |
| Vega-Gutierrez, J | 1 |
| Zhao, M | 1 |
| Yang, M | 1 |
| Que, W | 1 |
| Zhong, L | 1 |
| Fujino, M | 4 |
| Li, XK | 4 |
| Nakanishi, T | 1 |
| Kuragano, T | 1 |
| Nanami, M | 1 |
| Nagasawa, Y | 1 |
| Hasuike, Y | 1 |
| Liu, C | 2 |
| Zhu, P | 2 |
| Ito, H | 3 |
| Takahashi, K | 3 |
| Nakajima, M | 2 |
| Tanaka, T | 3 |
| Wang, J | 1 |
| Zhuang, J | 2 |
| Zou, H | 1 |
| Lerche, CM | 1 |
| Fabricius, S | 1 |
| Philipsen, PA | 1 |
| Nishio, Y | 1 |
| Prignano, F | 1 |
| Lotti, T | 1 |
| Spallanzani, A | 1 |
| Berti, S | 1 |
| de Giorgi, V | 1 |
| Moretti, S | 1 |
| Draga, RO | 1 |
| Grimbergen, MC | 1 |
| Kok, ET | 1 |
| Jonges, TN | 1 |
| van Swol, CF | 1 |
| Bosch, JL | 1 |
| Peng, C | 1 |
| Li, Y | 1 |
| Liang, H | 1 |
| Cheng, J | 1 |
| Li, Q | 1 |
| Sun, X | 1 |
| Li, Z | 1 |
| Wang, F | 1 |
| Guo, Y | 1 |
| Tian, Z | 1 |
| Yang, L | 1 |
| Tian, Y | 1 |
| Zhang, Z | 1 |
| Cao, W | 1 |
| Sato, K | 1 |
| Matsushita, K | 1 |
| Aoki, M | 1 |
| Fuziwara, J | 1 |
| Miyanari, S | 1 |
| Kamada, T | 1 |
| Németh, IB | 1 |
| Zsíros, O | 1 |
| Koreck, A | 1 |
| Bella, Z | 1 |
| Kiricsi, Á | 1 |
| Ignácz, F | 1 |
| Kadocsa, E | 1 |
| Kemény, L | 1 |
| Brooke, RC | 1 |
| Sinha, A | 1 |
| Sidhu, MK | 1 |
| Watson, RE | 1 |
| Church, MK | 1 |
| Friedmann, PS | 1 |
| Clough, GF | 1 |
| Rhodes, LE | 1 |
| Ghaffarifar, F | 1 |
| Jorjani, O | 1 |
| Mirshams, M | 1 |
| Miranbaygi, MH | 1 |
| Hosseini, ZK | 1 |
| Ruiz-Rodriguez, R | 1 |
| López, L | 1 |
| Candelas, D | 1 |
| Zelickson, B | 1 |
| Isaka, Y | 1 |
4 reviews available for aminolevulinic acid and Inflammation
| Article | Year |
|---|---|
Counteracting Side-effects of Photodynamic Therapy for Actinic Keratoses.
Topics: Aminolevulinic Acid; Drug-Related Side Effects and Adverse Reactions; Humans; Inflammation; Keratosi | 2022 |
Myeloid heme oxygenase-1: a new therapeutic target in anti-inflammation.
Topics: Aminolevulinic Acid; Animals; Cytoprotection; Enzyme Induction; Heme Oxygenase-1; Humans; Inflammati | 2018 |
Misdistribution of iron and oxidative stress in chronic kidney disease.
Topics: Aminolevulinic Acid; Anemia; Hematinics; Heme; Hepcidins; Humans; Inflammation; Iron; Iron Overload; | 2019 |
5-Aminolevulinic acid regulates the inflammatory response and alloimmune reaction.
Topics: Aminolevulinic Acid; Heme; Heme Oxygenase-1; Histocompatibility; Humans; Immunity; Immunologic Facto | 2016 |
3 trials available for aminolevulinic acid and Inflammation
| Article | Year |
|---|---|
Dietary supplementation with 5-aminolevulinic acid modulates growth performance and inflammatory responses in broiler chickens.
Topics: Aminolevulinic Acid; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; CD3 Complex; | 2012 |
Photodynamic therapy as a new treatment of cutaneous leishmaniasis.
Topics: Aminolevulinic Acid; Drug Administration Schedule; Drug Monitoring; Humans; Hyperpigmentation; Infla | 2006 |
Enhanced efficacy of photodynamic therapy after fractional resurfacing: fractional photodynamic rejuvenation.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Cosmetic Techniques; Edema; Erythema; Female; Follow | 2007 |
15 other studies available for aminolevulinic acid and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr | 2010 |
Effects of ALA-PDT on the macrophages in wound healing and its related mechanisms in vivo and in vitro.
Topics: Aminolevulinic Acid; Animals; Disease Models, Animal; Inflammation; Macrophages; Mice; Photochemothe | 2022 |
Inflammation burst after 5-aminolevulinic acid-photodynamic therapy for the treatment of actinic keratosis complicating rosacea: A case report.
Topics: Aged; Aminolevulinic Acid; Female; Humans; Hyperpigmentation; Inflammation; Keratosis, Actinic; Phot | 2022 |
The effect of 5-aminolevulinic acid on canine peripheral blood mononuclear cells.
Topics: Aminolevulinic Acid; Animals; Dog Diseases; Dogs; Heme; Humans; Inflammation; Leukocytes, Mononuclea | 2022 |
ALA-PDT augments intense inflammation in the treatment of acne vulgaris by COX2/TREM1 mediated M1 macrophage polarization.
Topics: Acne Vulgaris; Aminolevulinic Acid; Animals; Cyclooxygenase 2; Dinoprostone; Inflammation; Macrophag | 2023 |
5-ALA/SFC Ameliorates Endotoxin-Induced Ocular Inflammation in Rats by Inhibiting the NF-κB Signaling Pathway and Activating the HO-1/Nrf2 Signaling Pathway.
Topics: Aminolevulinic Acid; Animals; Endotoxins; Inflammation; Lipopolysaccharides; NF-E2-Related Factor 2; | 2023 |
Inflammatory response and cytokine levels induced by intralesional photodynamic therapy and 630-nm laser in a case series of basal cell carcinoma.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Combined Modality Therapy; Cyto | 2018 |
Combination of 5-aminolevulinic acid and iron prevents skin fibrosis in murine sclerodermatous graft-versus-host disease.
Topics: Aminolevulinic Acid; Animals; Collagen Type I; Cytokines; Disease Models, Animal; Drug Therapy, Comb | 2018 |
Correlation between treatment time, photobleaching, inflammation and pain after photodynamic therapy with methyl aminolevulinate on tape-stripped skin in healthy volunteers.
Topics: Adult; Aminolevulinic Acid; Erythema; Fluorescence; Forearm; Humans; Inflammation; Male; Middle Aged | 2015 |
Sequential effects of photodynamic treatment of basal cell carcinoma.
Topics: Aminolevulinic Acid; Apoptosis; Carcinoma, Basal Cell; Cytokines; Humans; Immunohistochemistry; In S | 2009 |
Photodynamic diagnosis (5-aminolevulinic acid) of transitional cell carcinoma after bacillus Calmette-Guérin immunotherapy and mitomycin C intravesical therapy.
Topics: Administration, Intravesical; Aminolevulinic Acid; Antibiotics, Antineoplastic; BCG Vaccine; Biopsy; | 2010 |
Detection and photodynamic therapy of inflamed atherosclerotic plaques in the carotid artery of rabbits.
Topics: Aminolevulinic Acid; Animals; Carotid Arteries; Inflammation; Macrophages; Male; Phagocytosis; Photo | 2011 |
Ultraviolet light and photodynamic therapy induce apoptosis in nasal polyps.
Topics: Adult; Aged; Aminolevulinic Acid; Apoptosis; Epithelial Cells; Female; Humans; Inflammation; Male; M | 2012 |
Histamine is released following aminolevulinic acid-photodynamic therapy of human skin and mediates an aminolevulinic acid dose-related immediate inflammatory response.
Topics: Adult; Aged; Aminolevulinic Acid; Cetirizine; Dose-Response Relationship, Drug; Erythema; Female; Hi | 2006 |
5-aminolaevulinic acid (ALA), enhances heme oxygenase (HO)-1 expression and attenuates tubulointerstitial fibrosis and renal apoptosis in chronic cyclosporine nephropathy.
Topics: Aminolevulinic Acid; Animals; Apoptosis; Atrophy; Cyclosporine; Cytokines; Drug Therapy, Combination | 2019 |