aminolevulinic acid has been researched along with Hyperplasia in 26 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our recent studies showed that a new topical 5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) protocol using a light-emitting diode (LED) light source is an effective and successful treatment modality for five cases of oral verrucous hyperplasia (OVH) and one case of verrucous carcinoma." | 7.73 | Successful treatment of oral verrucous hyperplasia and oral leukoplakia with topical 5-aminolevulinic acid-mediated photodynamic therapy. ( Chen, HM; Chiang, CP; Tsai, T; Tu, PC; Yeh, CY; Yu, CH, 2005) |
| "Our previous studies showed that topical 5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) is very effective for oral verrucous hyperplasia (OVH) and relatively less effective for oral leukoplakia (OL) lesions." | 3.79 | Expression of Bak and Bak/Mcl-1 ratio can predict photodynamic therapy outcome for oral verrucous hyperplasia and leukoplakia. ( Chen, HM; Chiang, CP; Lin, HP; Yu, CH, 2013) |
| "Our previous studies showed that oral verrucous hyperplasia (OVH) lesions can be successfully treated with a topical 5-aminolevulinic acid-mediated photodynamic therapy (topical ALA-PDT) protocol using a 635-nm light-emitting diode light source." | 3.74 | Photodynamic therapy outcome for oral verrucous hyperplasia depends on the clinical appearance, size, color, epithelial dysplasia, and surface keratin thickness of the lesion. ( Chen, HM; Cheng, SJ; Chiang, CP; Hung, HY; Tsai, T; Yu, CH, 2008) |
| "Our recent studies showed that a new topical 5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) protocol using a light-emitting diode (LED) light source is an effective and successful treatment modality for five cases of oral verrucous hyperplasia (OVH) and one case of verrucous carcinoma." | 3.73 | Successful treatment of oral verrucous hyperplasia and oral leukoplakia with topical 5-aminolevulinic acid-mediated photodynamic therapy. ( Chen, HM; Chiang, CP; Tsai, T; Tu, PC; Yeh, CY; Yu, CH, 2005) |
| "The reported numbers of PMDS and HNSCC ranged between 5 and 225." | 2.58 | Photodynamic treatment outcomes of potentially-malignant lesions and malignancies of the head and neck region: A systematic review. ( Choudhary, MG; Gadbail, AR; Gondivkar, SM; Likhitkar, MS; Vedpathak, PR, 2018) |
| "Early diagnosis of laryngeal cancer and its precursor lesions is simplified." | 1.34 | Indirect fluorescence laryngoscopy in the diagnosis of precancerous and cancerous laryngeal lesions. ( Arens, C; Betz, CS; Glanz, H; Leunig, A; Reussner, D; Woenkhaus, J, 2007) |
| "5-Aminolevulinic acid was instilled prior to cystoscopy and biopsies were taken of lesions that were either fluorescing or nonfluorescing." | 1.29 | Intravesical instillation of 5-aminolevulinic acid: the fluorescent metabolite is limited to urothelial cells. ( Baumgartner, R; Hofstädter, F; Knüchel, R; Kriegmair, M; Steinbach, P, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (11.54) | 18.2507 |
| 2000's | 12 (46.15) | 29.6817 |
| 2010's | 9 (34.62) | 24.3611 |
| 2020's | 2 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Ou, J | 1 |
| Gao, Y | 1 |
| Li, H | 1 |
| Ling, T | 1 |
| Xie, X | 1 |
| Jin, Q | 1 |
| Li, W | 1 |
| Wu, W | 1 |
| Zhang, H | 1 |
| Zhao, F | 1 |
| Zhang, Q | 1 |
| Zhang, C | 1 |
| Gondivkar, SM | 1 |
| Gadbail, AR | 1 |
| Choudhary, MG | 1 |
| Vedpathak, PR | 1 |
| Likhitkar, MS | 1 |
| Kohoutova, D | 1 |
| Haidry, R | 1 |
| Banks, M | 1 |
| Butt, MA | 1 |
| Dunn, J | 1 |
| Thorpe, S | 1 |
| Lovat, L | 1 |
| Chen, HM | 6 |
| Cheng, SJ | 2 |
| Chiang, CP | 6 |
| Rosin, FC | 1 |
| Barcessat, AR | 1 |
| Borges, GG | 1 |
| Corrêa, L | 1 |
| Wang, X | 1 |
| Cao, P | 1 |
| Liu, J | 1 |
| Du, P | 1 |
| Wang, Z | 1 |
| Chen, W | 1 |
| Liu, C | 1 |
| Wu, Y | 1 |
| Zawislak, AA | 1 |
| McCluggage, WG | 1 |
| Donnelly, RF | 1 |
| Maxwell, P | 1 |
| Price, JH | 1 |
| Dobbs, SP | 1 |
| McClelland, HR | 1 |
| Woolfson, AD | 1 |
| Mccarron, PA | 1 |
| Kim, HS | 1 |
| Lee, HJ | 1 |
| Lee, JY | 1 |
| Kim, HO | 1 |
| Park, YM | 1 |
| Li, Q | 1 |
| Jiao, B | 1 |
| Long, HA | 1 |
| Lin, HP | 2 |
| Yu, CH | 4 |
| Yang, H | 2 |
| Wang, YP | 2 |
| Gabeler, EE | 2 |
| van Hillegersberg, R | 2 |
| Statius van Eps, RG | 2 |
| Sluiter, W | 2 |
| Mulder, P | 1 |
| van Urk, H | 2 |
| Horio, T | 1 |
| Horio, O | 1 |
| Miyauchi-Hashimoto, H | 1 |
| Ohnuki, M | 1 |
| Isei, T | 1 |
| Kliffen, M | 1 |
| Honkoop, J | 1 |
| Carlier, SG | 1 |
| Alster, TS | 1 |
| Tanzi, EL | 1 |
| Chen, CT | 1 |
| Kuo, MY | 1 |
| Kuo, YS | 1 |
| Lan, WH | 1 |
| Tsai, T | 3 |
| Tu, PC | 1 |
| Yeh, CY | 1 |
| Perrett, CM | 1 |
| McGregor, J | 1 |
| Barlow, RJ | 1 |
| Karran, P | 1 |
| Proby, C | 1 |
| Harwood, CA | 1 |
| Richey, DF | 1 |
| Arens, C | 1 |
| Reussner, D | 1 |
| Woenkhaus, J | 1 |
| Leunig, A | 1 |
| Betz, CS | 1 |
| Glanz, H | 1 |
| Kim, SK | 1 |
| Do, JE | 1 |
| Kang, HY | 1 |
| Lee, ES | 1 |
| Kim, YC | 1 |
| Hung, HY | 1 |
| Nyamekye, I | 1 |
| Anglin, S | 1 |
| McEwan, J | 1 |
| MacRobert, A | 1 |
| Bown, S | 1 |
| Bishop, C | 1 |
| Steinbach, P | 1 |
| Kriegmair, M | 1 |
| Baumgartner, R | 1 |
| Hofstädter, F | 1 |
| Knüchel, R | 1 |
| Eker, C | 1 |
| Montán, S | 1 |
| Jaramillo, E | 1 |
| Koizumi, K | 1 |
| Rubio, C | 1 |
| Andersson-Engels, S | 1 |
| Svanberg, K | 1 |
| Svanberg, S | 1 |
| Slezak, P | 1 |
2 reviews available for aminolevulinic acid and Hyperplasia
| Article | Year |
|---|---|
Photodynamic treatment outcomes of potentially-malignant lesions and malignancies of the head and neck region: A systematic review.
Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Chlorophyllides; Databases, Factual; Dihematoporphyri | 2018 |
Aminolevulinic acid photodynamic therapy for sebaceous gland hyperplasia.
Topics: Aminolevulinic Acid; Facial Dermatoses; Humans; Hyperplasia; Photochemotherapy; Photosensitizing Age | 2007 |
3 trials available for aminolevulinic acid and Hyperplasia
| Article | Year |
|---|---|
Long-term outcomes of the randomized controlled trial comparing 5-aminolaevulinic acid and Photofrin photodynamic therapy for Barrett's oesophagus related neoplasia.
Topics: Adenocarcinoma; Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Catheter Ablation; Dihematoporp | 2018 |
Response of vulval lichen sclerosus and squamous hyperplasia to photodynamic treatment using sustained topical delivery of aminolevulinic acid from a novel bioadhesive patch system.
Topics: Adhesiveness; Administration, Cutaneous; Aminolevulinic Acid; Female; Humans; Hyperplasia; Photochem | 2009 |
Photodynamic therapy with topical aminolevulinic acid and pulsed dye laser irradiation for sebaceous hyperplasia.
Topics: Administration, Cutaneous; Adult; Aminolevulinic Acid; Female; Humans; Hyperplasia; Low-Level Light | 2003 |
21 other studies available for aminolevulinic acid and Hyperplasia
| Article | Year |
|---|---|
Application of 5-aminolevulinic acid-mediated Waterlase-assisted photodynamic therapy in the treatment of oral leukoplakia.
Topics: Aminolevulinic Acid; Humans; Hyperplasia; Leukoplakia, Oral; Photochemotherapy; Photosensitizing Age | 2022 |
Assessment of 5-Aminolaevulinic Acid Photodynamic Therapy (ALA-PDT) in Chinese patients with actinic keratosis: Correlation of dermoscopic features with histopathology.
Topics: Aminolevulinic Acid; Blood Vessels; China; Dermoscopy; Humans; Hyperplasia; Keratosis, Actinic; Phot | 2020 |
Topical photodynamic therapy is the first-line treatment of choice for oral erythroleukoplakia and oral verrucous hyperplasia.
Topics: Aminolevulinic Acid; Carcinoma, Verrucous; Humans; Hyperplasia; Leukoplakia, Oral; Mouth; Photochemo | 2015 |
Effect of 5-ALA-mediated photodynamic therapy on mast cell and microvessels densities present in oral premalignant lesions induced in rats.
Topics: 4-Nitroquinoline-1-oxide; Aminolevulinic Acid; Animals; Antigens, CD34; Cell Degranulation; Female; | 2015 |
5-Aminolaevulinic Acid-Based Photodynamic Therapy Restrains Pathological Hyperplasia of Fibroblasts.
Topics: Adult; Aminolevulinic Acid; Apoptosis; Cell Differentiation; Cells, Cultured; Cicatrix; Collagen; Fe | 2017 |
Papular skin lesions in the retroauricular area: a quiz. Premature sebaceous hyperplasia en plaque.
Topics: Administration, Topical; Adolescent; Aminolevulinic Acid; Biopsy; Ear Auricle; Humans; Hyperplasia; | 2010 |
Pseudoepitheliomatous hyperplasia treated by photodynamic therapy with variable irradiation dose and concentration of photosensitizer.
Topics: Adult; Aminolevulinic Acid; Epidermis; Female; Humans; Hyperplasia; Middle Aged; Photochemotherapy; | 2011 |
Topical photodynamic therapy is very effective for oral verrucous hyperplasia and oral erythroleukoplakia.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma in Situ; Erythroplasia; Femal | 2010 |
Expression of Bak and Bak/Mcl-1 ratio can predict photodynamic therapy outcome for oral verrucous hyperplasia and leukoplakia.
Topics: Adult; Aged; Aminolevulinic Acid; bcl-2 Homologous Antagonist-Killer Protein; Biomarkers; Biopsy; Ca | 2013 |
Endovascular photodynamic therapy with aminolaevulinic acid prevents balloon induced intimal hyperplasia and constrictive remodelling.
Topics: Aminolevulinic Acid; Angioplasty, Balloon; Animals; Constriction, Pathologic; Disease Models, Animal | 2002 |
Photodynamic therapy of sebaceous hyperplasia with topical 5-aminolaevulinic acid and slide projector.
Topics: Aminolevulinic Acid; Facial Dermatoses; Humans; Hyperplasia; Male; Middle Aged; Photochemotherapy; P | 2003 |
Arterial wall strength after endovascular photodynamic therapy.
Topics: Aminolevulinic Acid; Angioplasty, Balloon; Animals; Disease Models, Animal; Hyperplasia; Iliac Arter | 2003 |
Successful treatment of oral verrucous hyperplasia with topical 5-aminolevulinic acid-mediated photodynamic therapy.
Topics: Adult; Aminolevulinic Acid; Humans; Hyperplasia; Male; Middle Aged; Mouth Diseases; Mouth Neoplasms; | 2004 |
Successful treatment of oral verrucous hyperplasia and oral leukoplakia with topical 5-aminolevulinic acid-mediated photodynamic therapy.
Topics: Administration, Topical; Adult; Aged; Aminolevulinic Acid; Carcinoma, Verrucous; Drug Administration | 2005 |
Topical photodynamic therapy with methyl aminolevulinate to treat sebaceous hyperplasia in an organ transplant recipient.
Topics: Administration, Cutaneous; Adult; Aminolevulinic Acid; Diagnosis, Differential; Humans; Hyperplasia; | 2006 |
Indirect fluorescence laryngoscopy in the diagnosis of precancerous and cancerous laryngeal lesions.
Topics: Aminolevulinic Acid; Diagnosis, Differential; Fluorescence; Humans; Hyperplasia; Laryngeal Diseases; | 2007 |
Combination of topical 5-aminolevulinic acid-photodynamic therapy with carbon dioxide laser for sebaceous hyperplasia.
Topics: Administration, Topical; Adolescent; Adult; Aminolevulinic Acid; Carbon Dioxide; Child; Child, Presc | 2007 |
Photodynamic therapy outcome for oral verrucous hyperplasia depends on the clinical appearance, size, color, epithelial dysplasia, and surface keratin thickness of the lesion.
Topics: Administration, Topical; Adult; Aged; Aminolevulinic Acid; Carcinoma, Verrucous; Female; Humans; Hyp | 2008 |
Photodynamic therapy of normal and balloon-injured rat carotid arteries using 5-amino-levulinic acid.
Topics: Aminolevulinic Acid; Angioplasty, Balloon; Animals; Carotid Arteries; Carotid Artery Diseases; Const | 1995 |
Intravesical instillation of 5-aminolevulinic acid: the fluorescent metabolite is limited to urothelial cells.
Topics: Administration, Intravesical; Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Papillary; Cell Lin | 1994 |
Clinical spectral characterisation of colonic mucosal lesions using autofluorescence and delta aminolevulinic acid sensitisation.
Topics: Adenoma; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Colon; Colonic Neoplasms; Colonoscopy; | 1999 |