aminolevulinic acid has been researched along with Hyperpigmentation in 12 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
Hyperpigmentation: Excessive pigmentation of the skin, usually as a result of increased epidermal or dermal melanin pigmentation, hypermelanosis. Hyperpigmentation can be localized or generalized. The condition may arise from exposure to light, chemicals or other substances, or from a primary metabolic imbalance.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Aminolevulinic acid (ALA) photodynamic therapy (PDT) is an established treatment option for actinic keratosis (AK), and recently fractional carbon dioxide (CO2) laser was shown to improve outcomes; but studies of short incubation photosensitizer are lacking." | 9.24 | Randomized, Controlled Trial of Fractional Carbon Dioxide Laser Resurfacing Followed by Ultrashort Incubation Aminolevulinic Acid Blue Light Photodynamic Therapy for Actinic Keratosis. ( Alexiades, M, 2017) |
| "A 72-year-old woman suffering from multiple actinic keratosis (AK) complicating steroid-induced rosacea received 5-aminolevulinic acid-photodynamic therapy (ALA-PDT) in our outpatient clinic." | 8.12 | Inflammation burst after 5-aminolevulinic acid-photodynamic therapy for the treatment of actinic keratosis complicating rosacea: A case report. ( Cao, Y; Hu, C; Liu, P; Liu, X; Wang, P; Wang, X; Yang, X; Zhang, L, 2022) |
| "Aminolevulinic acid (ALA) photodynamic therapy (PDT) is an established treatment option for actinic keratosis (AK), and recently fractional carbon dioxide (CO2) laser was shown to improve outcomes; but studies of short incubation photosensitizer are lacking." | 5.24 | Randomized, Controlled Trial of Fractional Carbon Dioxide Laser Resurfacing Followed by Ultrashort Incubation Aminolevulinic Acid Blue Light Photodynamic Therapy for Actinic Keratosis. ( Alexiades, M, 2017) |
| "A 72-year-old woman suffering from multiple actinic keratosis (AK) complicating steroid-induced rosacea received 5-aminolevulinic acid-photodynamic therapy (ALA-PDT) in our outpatient clinic." | 4.12 | Inflammation burst after 5-aminolevulinic acid-photodynamic therapy for the treatment of actinic keratosis complicating rosacea: A case report. ( Cao, Y; Hu, C; Liu, P; Liu, X; Wang, P; Wang, X; Yang, X; Zhang, L, 2022) |
| "Hyperpigmentation-melasma was treated in a 31-year-old female with the application of aminolevulinic acid HCL 20%-single use Levulan Kerastick followed by exposure to 10 J/cm2 of nonlaser blue light." | 3.73 | Treatment of hyperpigmentation-melasma with photodynamic therapy. ( Marcus, L, 2006) |
| "Hyperpigmentation was more common at higher doses of light, and pain was experienced more often by the patients when higher doses were used." | 2.73 | Photodynamic therapy for acne vulgaris: a pilot study of the dose-response and mechanism of action. ( Faergemann, J; Hörfelt, C; Larkö, O; Stenquist, B; Wennberg, AM, 2007) |
| "acnes was measured in a skin surface biopsy using a cyano-acrylate polymer to extract the content of the sebaceous follicles." | 2.73 | Photodynamic therapy for acne vulgaris: a pilot study of the dose-response and mechanism of action. ( Faergemann, J; Hörfelt, C; Larkö, O; Stenquist, B; Wennberg, AM, 2007) |
| "Acne vulgaris is a chronic inflammatory skin disease around pilosebaceous unit." | 1.72 | A prospective study of adverse reactions of ALA-PDT for acne vulgaris. ( Liu, X; Shi, L; Wang, P; Wang, X; Yan, G; Yang, J; Zhang, G; Zhang, H; Zhang, L; Zhang, Y; Zhou, Z, 2022) |
| "Hyperpigmentation was more likely to occur in skin appendage disorders (P<0." | 1.72 | Adverse reactions of ALA-PDT for the treatment of cutaneous diseases: A retrospective study. ( Shi, L; Wang, P; Wang, X; Yan, G; Yang, J; Zhang, G; Zhang, H; Zhang, L; Zhang, Y; Zhou, Z, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 8 (66.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 3 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shi, L | 2 |
| Yang, J | 4 |
| Zhang, L | 3 |
| Zhang, Y | 2 |
| Yan, G | 2 |
| Zhang, H | 2 |
| Liu, X | 2 |
| Wang, P | 3 |
| Zhang, G | 2 |
| Zhou, Z | 2 |
| Wang, X | 3 |
| Liu, P | 1 |
| Hu, C | 1 |
| Yang, X | 1 |
| Cao, Y | 1 |
| Alexiades, M | 1 |
| Terrell, S | 1 |
| Aires, D | 1 |
| Schweiger, ES | 1 |
| Monfrecola, G | 1 |
| Procaccini, EM | 1 |
| D'Onofrio, D | 1 |
| Roberti, G | 1 |
| Liuzzi, R | 1 |
| Staibano, S | 1 |
| Manco, A | 1 |
| De Rosa, G | 1 |
| Santoianni, P | 1 |
| Marcus, L | 1 |
| Zane, C | 1 |
| Capezzera, R | 1 |
| Sala, R | 1 |
| Venturini, M | 1 |
| Calzavara-Pinton, P | 1 |
| Ghaffarifar, F | 1 |
| Jorjani, O | 1 |
| Mirshams, M | 1 |
| Miranbaygi, MH | 1 |
| Hosseini, ZK | 1 |
| Hörfelt, C | 1 |
| Stenquist, B | 1 |
| Larkö, O | 1 |
| Faergemann, J | 1 |
| Wennberg, AM | 1 |
| Ruiz-Rodriguez, R | 1 |
| López, L | 1 |
| Candelas, D | 1 |
| Zelickson, B | 1 |
| Yung, A | 1 |
| Stables, GI | 1 |
| Fernandez, C | 1 |
| Williams, J | 1 |
| Bojar, RA | 1 |
| Goulden, V | 1 |
6 trials available for aminolevulinic acid and Hyperpigmentation
| Article | Year |
|---|---|
Randomized, Controlled Trial of Fractional Carbon Dioxide Laser Resurfacing Followed by Ultrashort Incubation Aminolevulinic Acid Blue Light Photodynamic Therapy for Actinic Keratosis.
Topics: Aminolevulinic Acid; Erythema; Esthetics; Follow-Up Studies; Humans; Hyperpigmentation; Keratosis, A | 2017 |
Clinical and echographic analysis of photodynamic therapy using methylaminolevulinate as sensitizer in the treatment of photodamaged facial skin.
Topics: Aged; Aminolevulinic Acid; Female; Humans; Hyperpigmentation; Keratosis; Male; Middle Aged; Patient | 2007 |
Photodynamic therapy as a new treatment of cutaneous leishmaniasis.
Topics: Aminolevulinic Acid; Drug Administration Schedule; Drug Monitoring; Humans; Hyperpigmentation; Infla | 2006 |
Photodynamic therapy for acne vulgaris: a pilot study of the dose-response and mechanism of action.
Topics: Acne Vulgaris; Adolescent; Adult; Aminolevulinic Acid; Female; Humans; Hyperpigmentation; Male; Pain | 2007 |
Enhanced efficacy of photodynamic therapy after fractional resurfacing: fractional photodynamic rejuvenation.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Cosmetic Techniques; Edema; Erythema; Female; Follow | 2007 |
Microbiological effect of photodynamic therapy (PDT) in healthy volunteers: a comparative study using methyl aminolaevulinate and hexyl aminolaevulinate cream.
Topics: Adolescent; Adult; Aminolevulinic Acid; Double-Blind Method; Erythema; Female; Humans; Hyperpigmenta | 2007 |
6 other studies available for aminolevulinic acid and Hyperpigmentation
| Article | Year |
|---|---|
A prospective study of adverse reactions of ALA-PDT for acne vulgaris.
Topics: Acne Vulgaris; Aminolevulinic Acid; China; Female; Humans; Hyperpigmentation; Male; Pain; Photochemo | 2022 |
Adverse reactions of ALA-PDT for the treatment of cutaneous diseases: A retrospective study.
Topics: Aged; Aminolevulinic Acid; China; Erythema; Female; Humans; Hyperpigmentation; Hypopigmentation; Pho | 2022 |
Inflammation burst after 5-aminolevulinic acid-photodynamic therapy for the treatment of actinic keratosis complicating rosacea: A case report.
Topics: Aged; Aminolevulinic Acid; Female; Humans; Hyperpigmentation; Inflammation; Keratosis, Actinic; Phot | 2022 |
Treatment of acne vulgaris using blue light photodynamic therapy in an African-American patient.
Topics: Acne Vulgaris; Adult; Aminolevulinic Acid; Black or African American; Female; Humans; Hydroquinones; | 2009 |
Hyperpigmentation induced by topical 5-aminolaevulinic acid plus visible light.
Topics: Administration, Topical; Adult; Aminolevulinic Acid; Colorimetry; Female; Humans; Hyperpigmentation; | 2002 |
Treatment of hyperpigmentation-melasma with photodynamic therapy.
Topics: Adult; Aminolevulinic Acid; Female; Humans; Hyperpigmentation; Melanosis; Photochemotherapy; Photose | 2006 |