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aminolevulinic acid and Hand Dermatoses

aminolevulinic acid has been researched along with Hand Dermatoses in 17 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Hand Dermatoses: Skin diseases involving the HANDS.

Research Excerpts

ExcerptRelevanceReference
"We carried out a prospective, single-arm, phase II study of 5-aminolevulinic acid (5-ALA)-PDT in the treatment of recalcitrant viral warts in an Asian population."9.12Photodynamic therapy with 20% aminolevulinic acid for the treatment of recalcitrant viral warts in an Asian population. ( Kwok, C; Tan, E; Tay, YK; Wang, YS, 2007)
"We carried out a prospective, single-arm, phase II study of 5-aminolevulinic acid (5-ALA)-PDT in the treatment of recalcitrant viral warts in an Asian population."5.12Photodynamic therapy with 20% aminolevulinic acid for the treatment of recalcitrant viral warts in an Asian population. ( Kwok, C; Tan, E; Tay, YK; Wang, YS, 2007)
" Herein, we report one case of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) combined with antibiotics for the treatment of multiple skin abscesses in the hands caused by M."3.83ALA-PDT combined with antibiotics for the treatment of multiple skin abscesses caused by Mycobacterium fortuitum. ( Gong, N; Lei, X; Li, M; Lu, W; Tan, Y, 2016)
"Erythema was significantly more severe (P=0."2.76Effect of retinoid pretreatment on outcomes of patients treated by photodynamic therapy for actinic keratosis of the hand and forearm. ( Galitzer, BI, 2011)
" Herein, we report one case of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) combined with antibiotics for the treatment of multiple skin abscesses in the hands caused by M."1.43ALA-PDT combined with antibiotics for the treatment of multiple skin abscesses caused by Mycobacterium fortuitum. ( Gong, N; Lei, X; Li, M; Lu, W; Tan, Y, 2016)
"PDT can offer a good alternative for treating periungual warts of the hands."1.34Successful treatment of periungual warts using photodynamic therapy: a pilot study. ( Bos, PM; Kaas, L; Neumann, HA; Schroeter, CA; Waterval, JJ, 2007)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (11.76)18.2507
2000's8 (47.06)29.6817
2010's7 (41.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Togsverd-Bo, K1
Halldin, C1
Sandberg, C1
Gonzalez, H1
Wennberg, AM1
Sørensen, SS1
Wulf, HC4
Haedersdal, M1
Gong, N1
Tan, Y1
Li, M1
Lu, W1
Lei, X1
Kohl, E1
Popp, C1
Zeman, F1
Unger, P1
Koller, M1
Landthaler, M2
Karrer, S2
Szeimies, RM2
Nissen, CV1
Heerfordt, IM1
Wiegell, SR1
Mikkelsen, CS1
Fernández-Guarino, M1
Harto, A1
Sánchez-Ronco, M1
Pérez-García, B1
Marquet, A1
Jaén, P1
Van der Geer, S1
Krekels, GA1
Aspiroz, C2
Gilaberte, Y2
Paz-Cristóbal, P1
Rezusta, A2
Martes, MP1
Alcalde, V1
Espinel-Ingroff, A1
Galitzer, BI1
Escudero, A1
Nagore, E1
Sevila, A1
Sanmartin, O1
Botella, R1
Guillen, C1
Stender, IM2
Borgbjerg, FM1
Villumsen, J1
Lock-Andersen, J2
Kim, JY1
Kang, HY1
Lee, ES1
Kim, YC1
Schroeter, CA1
Kaas, L1
Waterval, JJ1
Bos, PM1
Neumann, HA1
Wang, YS1
Tay, YK1
Kwok, C1
Tan, E1
Abels, C1
Wlotzke, U1
Stolz, W1
Bastuji-Garin, S1
Laurent, R1
Basset-Seguin, N1
Bédane, C1
Combemale, P1
Dubertret, L1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Portable Measurement of Protoporphyrin IX in the Skin[NCT04223570]218 participants (Anticipated)Observational2022-12-01Enrolling by invitation
Topical Imiquimod 5% Cream Therapy Versus Photodynamic Therapy With Methyl-aminolaevulinate 16% Cream of Actinic Keratoses in Organ Transplant Recipients[NCT01538901]Phase 410 participants (Actual)Interventional2012-09-30Terminated (stopped due to prolonged recruitment phase)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

8 trials available for aminolevulinic acid and Hand Dermatoses

ArticleYear
Photodynamic therapy is more effective than imiquimod for actinic keratosis in organ transplant recipients: a randomized intraindividual controlled trial.
    The British journal of dermatology, 2018, Volume: 178, Issue:4

    Topics: Aged; Aminolevulinic Acid; Drug Eruptions; Facial Dermatoses; Female; Hand Dermatoses; Humans; Imiqu

2018
Photodynamic therapy using intense pulsed light for treating actinic keratoses and photoaged skin of the dorsal hands: a randomized placebo-controlled study.
    The British journal of dermatology, 2017, Volume: 176, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Double-Blind Method; Esthetics; Female; Hand De

2017
Increased protoporphyrin IX accumulation does not improve the effect of photodynamic therapy for actinic keratosis: a randomized controlled trial.
    The British journal of dermatology, 2017, Volume: 176, Issue:5

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Curettage; Drug Eruptions; Erythema; Female; Fluoresce

2017
Treatment of actinic keratoses on the dorsum of the hands: ALA-PDT versus diclofenac 3% gel followed by ALA-PDT. A placebo-controlled, double-blind, pilot study.
    The Journal of dermatological treatment, 2009, Volume: 20, Issue:5

    Topics: Administration, Cutaneous; Aged; Aminolevulinic Acid; Anti-Inflammatory Agents, Non-Steroidal; Diclo

2009
Effect of retinoid pretreatment on outcomes of patients treated by photodynamic therapy for actinic keratosis of the hand and forearm.
    Journal of drugs in dermatology : JDD, 2011, Volume: 10, Issue:10

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Aminolevulinic Acid; Dermatologic Agents; Erythe

2011
Pain induced by photodynamic therapy of warts.
    Photodermatology, photoimmunology & photomedicine, 2006, Volume: 22, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Foot Dermatoses; Hand Dermatoses; Human

2006
Photodynamic therapy with 20% aminolevulinic acid for the treatment of recalcitrant viral warts in an Asian population.
    International journal of dermatology, 2007, Volume: 46, Issue:11

    Topics: Adolescent; Adult; Aged; Aminolevulinic Acid; Female; Foot Dermatoses; Hand Dermatoses; Humans; Male

2007
Recalcitrant hand and foot warts successfully treated with photodynamic therapy with topical 5-aminolaevulinic acid: a pilot study.
    Clinical and experimental dermatology, 1999, Volume: 24, Issue:3

    Topics: Administration, Topical; Adult; Aged; Aminolevulinic Acid; Cryotherapy; Female; Foot Dermatoses; Han

1999

Other Studies

9 other studies available for aminolevulinic acid and Hand Dermatoses

ArticleYear
ALA-PDT combined with antibiotics for the treatment of multiple skin abscesses caused by Mycobacterium fortuitum.
    Photodiagnosis and photodynamic therapy, 2016, Volume: 15

    Topics: Abscess; Administration, Cutaneous; Adult; Aminolevulinic Acid; Anti-Bacterial Agents; Dose-Response

2016
[Retrospective, descriptive, observational study of treatment of multiple actinic keratoses with topical methyl aminolevulinate and red light: results in clinical practice and correlation with fluorescence imaging].
    Actas dermo-sifiliograficas, 2008, Volume: 99, Issue:10

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Aminolevulinic Acid; Facial Dermatoses; Female;

2008
[Distal onycholysis resolved with photodynamic therapy in an elderly patient on multiple medication].
    Enfermedades infecciosas y microbiologia clinica, 2011, Volume: 29, Issue:8

    Topics: Aged; Aminolevulinic Acid; Candidiasis, Cutaneous; Dermatomycoses; Hand Dermatoses; Humans; Malassez

2011
Treatment of refractory fingernail onychomycosis caused by nondermatophyte molds with methylaminolevulinate photodynamic therapy.
    Journal of the American Academy of Dermatology, 2011, Volume: 65, Issue:3

    Topics: Adult; Aminolevulinic Acid; Aspergillosis; Female; Fusarium; Hand Dermatoses; Humans; Middle Aged; O

2011
Chronic X-ray dermatitis treated by topical 5-aminolaevulinic acid-photodynamic therapy.
    The British journal of dermatology, 2002, Volume: 147, Issue:2

    Topics: Aged; Aminolevulinic Acid; Chronic Disease; Dermatitis, Occupational; Hand Dermatoses; Humans; Male;

2002
Topical 5-aminolaevulinic acid photodynamic therapy for intractable palmoplantar psoriasis.
    The Journal of dermatology, 2007, Volume: 34, Issue:1

    Topics: Adult; Aminolevulinic Acid; Foot Dermatoses; Hand Dermatoses; Humans; Male; Middle Aged; Photochemot

2007
Successful treatment of periungual warts using photodynamic therapy: a pilot study.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2007, Volume: 21, Issue:9

    Topics: Administration, Topical; Adolescent; Adult; Aminolevulinic Acid; Child; Female; Hand Dermatoses; Hum

2007
Epidermodysplasia verruciformis treated using topical 5-aminolaevulinic acid photodynamic therapy.
    The British journal of dermatology, 1999, Volume: 140, Issue:5

    Topics: Administration, Topical; Aged; Aminolevulinic Acid; Arm; DNA, Viral; Epidermodysplasia Verruciformis

1999
[Photodynamic therapy with 5-aminolevulinic acid or placebo for recalcitrant foot and hand warts: randomised double-blind trial].
    Annales de dermatologie et de venereologie, 2001, Volume: 128, Issue:10 Pt 1

    Topics: Aminolevulinic Acid; Double-Blind Method; Foot Dermatoses; Hand Dermatoses; Humans; Photochemotherap

2001