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aminolevulinic acid and Hamartoma Syndrome, Multiple

aminolevulinic acid has been researched along with Hamartoma Syndrome, Multiple in 5 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Hamartoma Syndrome, Multiple: A hereditary disease characterized by multiple ectodermal, mesodermal, and endodermal nevoid and neoplastic anomalies. Facial trichilemmomas and papillomatous papules of the oral mucosa are the most characteristic lesions. Individuals with this syndrome have a high risk of BREAST CANCER; THYROID CANCER; and ENDOMETRIAL CANCER. This syndrome is associated with mutations in the gene for PTEN PHOSPHATASE.

Research Excerpts

ExcerptRelevanceReference
" For laser treatments, a sigmoidal light dose-response relationship predicted more than 85% initial response rates for light doses 150 J/cm(2) or more."1.33Treatment of diffuse basal cell carcinomas and basaloid follicular hamartomas in nevoid basal cell carcinoma syndrome by wide-area 5-aminolevulinic acid photodynamic therapy. ( Bellnier, DA; Blumenson, LE; Cheney, R; Frawley, NP; Oseroff, AR; Pivnick, EK; Shieh, S, 2005)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Cao, D1
Zhu, W1
Kuang, Y1
Zhao, S1
Li, C1
Chen, P1
Li, Z1
Wang, Y1
He, S1
Shi, M1
Wang, Q1
Xu, M1
Li, Q1
Chen, H1
Zeng, K1
Liang, J1
Zhang, X1
Liao, C1
Zhang, G1
Wang, P1
Sun, X1
Wang, X1
Rizzo, JM1
Segal, RJ1
Zeitouni, NC1
Oseroff, AR1
Shieh, S1
Frawley, NP1
Cheney, R1
Blumenson, LE1
Pivnick, EK1
Bellnier, DA1

Trials

1 trial available for aminolevulinic acid and Hamartoma Syndrome, Multiple

ArticleYear
Combination vismodegib and photodynamic therapy for multiple basal cell carcinomas.
    Photodiagnosis and photodynamic therapy, 2018, Volume: 21

    Topics: Aged; Aminolevulinic Acid; Anilides; Antineoplastic Agents; Carcinoma, Basal Cell; Combined Modality

2018

Other Studies

4 other studies available for aminolevulinic acid and Hamartoma Syndrome, Multiple

ArticleYear
A safe and effective treatment: Surgery combined with photodynamic therapy for multiple basal cell carcinomas.
    Photodiagnosis and photodynamic therapy, 2019, Volume: 28

    Topics: Aminolevulinic Acid; Carcinoma, Basal Cell; Combined Modality Therapy; Hamartoma Syndrome, Multiple;

2019
5-aminolevulinic acid photodynamic therapy and excision surgery for nevoid basal cell carcinoma syndrome with multiple basal cell carcinomas and PTCH1 mutation.
    Photodiagnosis and photodynamic therapy, 2020, Volume: 32

    Topics: Aminolevulinic Acid; Basal Cell Nevus Syndrome; Carcinoma, Basal Cell; Hamartoma Syndrome, Multiple;

2020
Combination curettage and modified ALA-PDT for multiple basal cell carcinomas of the face and head.
    Photodiagnosis and photodynamic therapy, 2021, Volume: 35

    Topics: Aminolevulinic Acid; Carcinoma, Basal Cell; Curettage; Hamartoma Syndrome, Multiple; Humans; Neoplas

2021
Treatment of diffuse basal cell carcinomas and basaloid follicular hamartomas in nevoid basal cell carcinoma syndrome by wide-area 5-aminolevulinic acid photodynamic therapy.
    Archives of dermatology, 2005, Volume: 141, Issue:1

    Topics: Adolescent; Aminolevulinic Acid; Basal Cell Nevus Syndrome; Child; Female; Hamartoma Syndrome, Multi

2005