aminolevulinic acid has been researched along with HPV Infection in 62 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effect of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) combined with CO2 laser pretreatment (Laser+ALA-PDT) on patients with cervical high-grade squamous intraepithelial lesions (HSILs)." | 8.31 | Effect of topical 5-aminolevulinic acid photodynamic therapy versus therapy combined with CO2 laser pretreatment for patients with cervical high-grade squamous intraepithelial lesions. ( Feng, C; Gu, L; Hong, Z; Qiu, L; Wang, L; Wei, Y; Wu, D, 2023) |
| "To evaluate the efficacy of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) in the treatment of high-grade squamous intraepithelial lesions of the cervix (HSIL)." | 8.12 | Topical 5-aminolevulinic acid photodynamic therapy for cervical high-grade squamous intraepithelial lesions. ( Chen, J; Hu, Y; Li, Y; Ma, L; Teng, Y; Xu, Y, 2022) |
| "To explore the therapeutic effect of topical 5-Aminolevulinic Acid photodynamic therapy (ALA-PDT) on laryngeal papillomatosis (LP) treatment." | 7.91 | Topical 5-aminolevulinic acid photodynamic therapy for laryngeal papillomatosistosis treatment. ( Cai, Q; Chen, R; Han, P; Huang, X; Liang, F; Lin, P; Luo, M, 2019) |
| " The goal of this study is to investigate the usefulness of 5-aminolevulinic acid (ALA)-assisted in situ fluorescence diagnosis of subclinical lesion and latent HPV infection." | 7.74 | Aminolevulinic acid (ALA)-assisted photodynamic diagnosis of subclinical and latent HPV infection of external genital region. ( Guo, MX; Huang, Z; Wang, HW; Wang, XL; Zhang, LL, 2008) |
| "Patients with cervical LSIL and HPV infection were divided into 3 treatment groups based on their own choice." | 7.30 | The effect of aminolevulinic acid hydrochloride topical powder photodynamic therapy versus nocardia rubra cell wall skeleton and observers group in the treatment of cervical low-grade squamous intraepithelial lesions with human papillomavirus infection: A ( Gong, H; Jiang, S; Nan, X; Pan, X; Tang, L; Zhang, J, 2023) |
| "Genital HPV infections are widely prevalent." | 6.87 | Treatment of latent or subclinical Genital HPV Infection with 5-aminolevulinic acid-based photodynamic therapy. ( Hu, Z; Jiang, L; Li, J; Liu, H; Liu, L; Zeng, K, 2018) |
| "To evaluate the effect of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) combined with CO2 laser pretreatment (Laser+ALA-PDT) on patients with cervical high-grade squamous intraepithelial lesions (HSILs)." | 5.91 | Effect of topical 5-aminolevulinic acid photodynamic therapy versus therapy combined with CO2 laser pretreatment for patients with cervical high-grade squamous intraepithelial lesions. ( Feng, C; Gu, L; Hong, Z; Qiu, L; Wang, L; Wei, Y; Wu, D, 2023) |
| "Cervical high-grade squamous intraepithelial lesions (HSIL), as pre-cancerous lesions, have a 5% chance of progressing to invasive cancer." | 5.72 | The effect of high-risk HPV E6/E7 mRNA on the efficacy of topical photodynamic therapy with 5-aminolevulinic acid for cervical high-grade squamous intraepithelial lesions. ( Cao, L; Qin, L; Shen, Y; Su, Y; Tang, Y; Wang, B; Wang, L; Zhang, L; Zhang, M; Zhang, T; Zhang, Y; Zhou, Y, 2022) |
| "Multiple-type HPV infection were closely associated with CA recurrence after photodynamic therapy." | 5.62 | Multiple-type HPV infection predicting condyloma acuminatum recurrence after aminolevulinic acid photodynamic therapy. ( Gu, L; Hua, H; Shi, Z; Zhou, B; Zhou, S, 2021) |
| "Multiple human papillomavirus infections are commonly encountered in genital warts." | 5.62 | Patterns of multiple human papillomavirus clearance during 5-aminolevulinic acid-based photodynamic therapy in patients with genital warts. ( Hu, Z; Zeng, K; Zheng, H, 2021) |
| "Progression to high-grade squamous intraepithelial lesion warrants intervention." | 5.62 | The effect of local photodynamic therapy with 5-aminolevulinic acid for the treatment of cervical low-grade squamous intraepithelial lesions with high-risk HPV infection: A retrospective study. ( Cheng, M; Di, W; Gu, L; Hong, Z; Qiu, L, 2021) |
| "High-risk HPV infection is the main cause of cervical cancer and pre-cancerous lesions." | 5.62 | The effect of local photodynamic therapy with 5-aminolevulinic acid for the treatment of cervical low-grade squamous intraepithelial lesions with high-risk HPV infection: A retrospective study. ( Cheng, M; Di, W; Gu, L; Hong, Z; Qiu, L, 2021) |
| "80 patients with CINI and HR-HPV infection were selected for the study." | 5.56 | Treatment of HPV Infection-Associated Low Grade Cervical Intraepithelial Neoplasia with 5-Aminolevulinic Acid-Mediated Photodynamic Therapy. ( Cai, Q; Li, D; Lin, L; Shi, L; Xu, Y; Zhang, F, 2020) |
| "The detection rate of HPV infections was 76." | 5.51 | Topical 5-aminolevulinic acid photodynamic therapy for laryngeal papillomatosistosis treatment. ( Cai, Q; Chen, R; Han, P; Huang, X; Liang, F; Lin, P; Luo, M, 2019) |
| "Latent HPV infections at 0." | 5.35 | Aminolevulinic acid (ALA)-assisted photodynamic diagnosis of subclinical and latent HPV infection of external genital region. ( Guo, MX; Huang, Z; Wang, HW; Wang, XL; Zhang, LL, 2008) |
| "The relatively high recurrence rate of genital warts can be attributed to the unsuccessful elimination of viruses in areas of subclinical and latent infection." | 5.35 | Aminolevulinic acid (ALA)-assisted photodynamic diagnosis of subclinical and latent HPV infection of external genital region. ( Guo, MX; Huang, Z; Wang, HW; Wang, XL; Zhang, LL, 2008) |
| "To evaluate the effect of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) combined with CO2 laser pretreatment (Laser+ALA-PDT) on patients with cervical high-grade squamous intraepithelial lesions (HSILs)." | 4.31 | Effect of topical 5-aminolevulinic acid photodynamic therapy versus therapy combined with CO2 laser pretreatment for patients with cervical high-grade squamous intraepithelial lesions. ( Feng, C; Gu, L; Hong, Z; Qiu, L; Wang, L; Wei, Y; Wu, D, 2023) |
| "Podophyllotoxin -combined ALA-PDT inhibited the proliferation and promoted apoptosis and necrosis more effectively than the single treatment at the same intensity and concentration." | 4.12 | Podophyllotoxin-combined 5-aminolevulinic acid photodynamic therapy significantly promotes HR-HPV-infected cell death. ( Chen, P; Li, C; Li, Q; Li, Z; Wang, J; Wang, Q; Xu, M; Zeng, K, 2022) |
| "To evaluate the efficacy of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) in the treatment of high-grade squamous intraepithelial lesions of the cervix (HSIL)." | 4.12 | Topical 5-aminolevulinic acid photodynamic therapy for cervical high-grade squamous intraepithelial lesions. ( Chen, J; Hu, Y; Li, Y; Ma, L; Teng, Y; Xu, Y, 2022) |
| " 5-aminolevulinic acid-mediated PDT (ALA-PDT) has been used in a variety of HR-HPV infection-related diseases." | 4.02 | Dihydroartemisinin administration improves the effectiveness of 5-aminolevulinic acid-mediated photodynamic therapy for the treatment of high-risk human papillomavirus infection. ( Feng, Y; Hu, H; Li, C; Li, Z; Lu, Y; Teng, M; Wang, Q; Wang, Y; Xiao, Z; Yang, B; Zeng, K, 2021) |
| "To explore the therapeutic effect of topical 5-Aminolevulinic Acid photodynamic therapy (ALA-PDT) on laryngeal papillomatosis (LP) treatment." | 3.91 | Topical 5-aminolevulinic acid photodynamic therapy for laryngeal papillomatosistosis treatment. ( Cai, Q; Chen, R; Han, P; Huang, X; Liang, F; Lin, P; Luo, M, 2019) |
| " The goal of this study is to investigate the usefulness of 5-aminolevulinic acid (ALA)-assisted in situ fluorescence diagnosis of subclinical lesion and latent HPV infection." | 3.74 | Aminolevulinic acid (ALA)-assisted photodynamic diagnosis of subclinical and latent HPV infection of external genital region. ( Guo, MX; Huang, Z; Wang, HW; Wang, XL; Zhang, LL, 2008) |
| "Patients with cervical LSIL and HPV infection were divided into 3 treatment groups based on their own choice." | 3.30 | The effect of aminolevulinic acid hydrochloride topical powder photodynamic therapy versus nocardia rubra cell wall skeleton and observers group in the treatment of cervical low-grade squamous intraepithelial lesions with human papillomavirus infection: A ( Gong, H; Jiang, S; Nan, X; Pan, X; Tang, L; Zhang, J, 2023) |
| "Current treatments of high-grade squamous intraepithelial lesion (HSIL) of the cervix are based on invasive surgical interventions, compromising cervical competence and functionality." | 3.11 | Multicentre, prospective, randomised controlled trial to evaluate hexaminolevulinate photodynamic therapy (Cevira) as a novel treatment in patients with high-grade squamous intraepithelial lesion: APRICITY phase 3 study protocol. ( Chen, F; Dannecker, C; Han, L; Hillemanns, P; Lang, J; Mokráš, C; Novák, Z; Sui, L; You, Z; Zhang, Y, 2022) |
| "Genital HPV infections are widely prevalent." | 2.87 | Treatment of latent or subclinical Genital HPV Infection with 5-aminolevulinic acid-based photodynamic therapy. ( Hu, Z; Jiang, L; Li, J; Liu, H; Liu, L; Zeng, K, 2018) |
| "To evaluate the effect of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) combined with CO2 laser pretreatment (Laser+ALA-PDT) on patients with cervical high-grade squamous intraepithelial lesions (HSILs)." | 1.91 | Effect of topical 5-aminolevulinic acid photodynamic therapy versus therapy combined with CO2 laser pretreatment for patients with cervical high-grade squamous intraepithelial lesions. ( Feng, C; Gu, L; Hong, Z; Qiu, L; Wang, L; Wei, Y; Wu, D, 2023) |
| "Comprehensive evaluation of HPV infection state helps to individualize ALA-PDT treatment scheme for CA patients and predict the therapeutic efficacy." | 1.91 | Evaluation of HPV infection helps to direct ALA-PDT of condyloma acuminata. ( Feng, S; Huang, X; Li, J; Liu, H; Peng, X; Song, W; Wei, J; Xu, M; Zeng, K; Zhong, M; Zhong, Y, 2023) |
| "A total of 227 CA patients with HPV infection and visible warts were recruited." | 1.91 | Evaluation of HPV infection helps to direct ALA-PDT of condyloma acuminata. ( Feng, S; Huang, X; Li, J; Liu, H; Peng, X; Song, W; Wei, J; Xu, M; Zeng, K; Zhong, M; Zhong, Y, 2023) |
| " The adverse reactions after PDT were mild, mainly manifested as increased vaginal secretions or burning/tingling." | 1.72 | Evaluation of the efficacy and safety of 5-aminolevulinic acid-mediated photodynamic therapy in women with high-risk HPV persistent infection after cervical conization. ( Huang, Y; Jia, L; Liu, X; Liu, Y; Wang, L; Zhang, J; Zhang, Y, 2022) |
| " These treatment methods involvevarious adverse reactions; therefore, it remains necessary to explore new treatment methods." | 1.72 | Enhancement of the cytotoxic effect of dihydroartemisinin in high-risk human papillomavirus-infected cells by aminolevulinic acid via the Bax/Bcl-2-caspase pathway. ( Che, Q; Li, C; Lu, H; Wang, Q; Zeng, K, 2022) |
| "Cervical high-grade squamous intraepithelial lesions (HSIL), as pre-cancerous lesions, have a 5% chance of progressing to invasive cancer." | 1.72 | The effect of high-risk HPV E6/E7 mRNA on the efficacy of topical photodynamic therapy with 5-aminolevulinic acid for cervical high-grade squamous intraepithelial lesions. ( Cao, L; Qin, L; Shen, Y; Su, Y; Tang, Y; Wang, B; Wang, L; Zhang, L; Zhang, M; Zhang, T; Zhang, Y; Zhou, Y, 2022) |
| "It was also observed that persistent HPV infection is a major risk factor for persistent disease." | 1.72 | Comparative study of topical 5-aminolevulinic acid photodynamic therapy (5-ALA-PDT) and surgery for the treatment of high-grade vaginal intraepithelial neoplasia. ( Cao, L; Qin, L; Shen, Y; Su, Y; Tang, Y; Wang, B; Zhang, M; Zhang, T; Zhang, Y; Zhou, M; Zhou, Y, 2022) |
| "Photodynamic therapy mediatied by 5-aminolevulinic acid is an effective and safe treatment for vaginal HSIL with minimal side effects." | 1.72 | Efficacy and safety of photodynamic therapy mediatied by 5-aminolevulinic acid for the treatment of vaginal high-grade intraepithelial lesions. ( Guo, H; Han, Q; Wu, Z; Zhang, X, 2022) |
| " The most common adverse event was increased vaginal discharge, other side effects include abdominal pain, vulvar pruritus, and vaginal bleeding." | 1.72 | Efficacy and safety of photodynamic therapy mediatied by 5-aminolevulinic acid for the treatment of vaginal high-grade intraepithelial lesions. ( Guo, H; Han, Q; Wu, Z; Zhang, X, 2022) |
| "High-risk HPV infection is the main cause of cervical cancer and pre-cancerous lesions." | 1.62 | The effect of local photodynamic therapy with 5-aminolevulinic acid for the treatment of cervical low-grade squamous intraepithelial lesions with high-risk HPV infection: A retrospective study. ( Cheng, M; Di, W; Gu, L; Hong, Z; Qiu, L, 2021) |
| "Progression to high-grade squamous intraepithelial lesion warrants intervention." | 1.62 | The effect of local photodynamic therapy with 5-aminolevulinic acid for the treatment of cervical low-grade squamous intraepithelial lesions with high-risk HPV infection: A retrospective study. ( Cheng, M; Di, W; Gu, L; Hong, Z; Qiu, L, 2021) |
| "ALA-PDT is effective on treating hrHPV infection in patients with no cervical lesions." | 1.62 | Effectiveness of photodynamic therapy with 5-aminolevulinic acid on HPV clearance in women without cervical lesions. ( Cang, W; Di, W; Gu, L; Hong, Z; Qiu, L; Wu, A, 2021) |
| "Multiple-type HPV infection were closely associated with CA recurrence after photodynamic therapy." | 1.62 | Multiple-type HPV infection predicting condyloma acuminatum recurrence after aminolevulinic acid photodynamic therapy. ( Gu, L; Hua, H; Shi, Z; Zhou, B; Zhou, S, 2021) |
| "Multiple human papillomavirus infections are commonly encountered in genital warts." | 1.62 | Patterns of multiple human papillomavirus clearance during 5-aminolevulinic acid-based photodynamic therapy in patients with genital warts. ( Hu, Z; Zeng, K; Zheng, H, 2021) |
| "80 patients with CINI and HR-HPV infection were selected for the study." | 1.56 | Treatment of HPV Infection-Associated Low Grade Cervical Intraepithelial Neoplasia with 5-Aminolevulinic Acid-Mediated Photodynamic Therapy. ( Cai, Q; Li, D; Lin, L; Shi, L; Xu, Y; Zhang, F, 2020) |
| "One hundred thirty-eight patients with HPV infection and visible anogenital warts were enrolled." | 1.51 | Evaluation of human papillomavirus DNA detection-guided aminolaevulinic acid-mediated photodynamic therapy for the treatment of condyloma acuminata. ( Che, Q; Jiang, L; Li, J; Li, S; Li, Z; Liu, H; Peng, X; Shi, M; Wang, J; Wang, Q; Zeng, K, 2019) |
| "Patients with non-high-risk (HR)-HPV infection required fewer PDT sessions than did those with HR-HPV infection by the end of treatment." | 1.51 | Evaluation of human papillomavirus DNA detection-guided aminolaevulinic acid-mediated photodynamic therapy for the treatment of condyloma acuminata. ( Che, Q; Jiang, L; Li, J; Li, S; Li, Z; Liu, H; Peng, X; Shi, M; Wang, J; Wang, Q; Zeng, K, 2019) |
| "Patients with multisite and multitype HPV infection required more PDT sessions to eliminate the virus." | 1.51 | Evaluation of human papillomavirus DNA detection-guided aminolaevulinic acid-mediated photodynamic therapy for the treatment of condyloma acuminata. ( Che, Q; Jiang, L; Li, J; Li, S; Li, Z; Liu, H; Peng, X; Shi, M; Wang, J; Wang, Q; Zeng, K, 2019) |
| "The detection rate of HPV infections was 76." | 1.51 | Topical 5-aminolevulinic acid photodynamic therapy for laryngeal papillomatosistosis treatment. ( Cai, Q; Chen, R; Han, P; Huang, X; Liang, F; Lin, P; Luo, M, 2019) |
| "Specimens from 41 patients with HPV infection were obtained, and the HPV genotypes and viral load were analyzed using real-time polymerase chain reaction (PCR) assays." | 1.48 | Dynamics of HPV viral loads reflect the treatment effect of photodynamic therapy in genital warts. ( Hu, Z; Jiang, L; Li, J; Liu, H; Liu, L; Zeng, K; Zhang, W, 2018) |
| "Patients with single type HPV infection had significantly higher rates of negative HPV DNA test results, as compared with patients with multiple infections after six rounds of PDT treatment; however, there was no difference in recurrence rates between the two groups." | 1.48 | Dynamics of HPV viral loads reflect the treatment effect of photodynamic therapy in genital warts. ( Hu, Z; Jiang, L; Li, J; Liu, H; Liu, L; Zeng, K; Zhang, W, 2018) |
| "Latent HPV infections at 0." | 1.35 | Aminolevulinic acid (ALA)-assisted photodynamic diagnosis of subclinical and latent HPV infection of external genital region. ( Guo, MX; Huang, Z; Wang, HW; Wang, XL; Zhang, LL, 2008) |
| "The relatively high recurrence rate of genital warts can be attributed to the unsuccessful elimination of viruses in areas of subclinical and latent infection." | 1.35 | Aminolevulinic acid (ALA)-assisted photodynamic diagnosis of subclinical and latent HPV infection of external genital region. ( Guo, MX; Huang, Z; Wang, HW; Wang, XL; Zhang, LL, 2008) |
| "In this study, we have assessed: (a) HPV infection; (b) HLA expression; and (c) immune infiltrating cells in VIN biopsies from responders and nonresponders to determine whether these factors may limit response to topical 5-aminolevulinic acid-based PDT." | 1.31 | Immunological and viral factors associated with the response of vulval intraepithelial neoplasia to photodynamic therapy. ( Abdel-Hady, ES; Corbitt, G; Duggan-Keen, M; Hampson, IN; Kitchener, HC; Martin-Hirsch, P; Moore, JV; Stern, PL, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (1.61) | 18.2507 |
| 2000's | 5 (8.06) | 29.6817 |
| 2010's | 14 (22.58) | 24.3611 |
| 2020's | 42 (67.74) | 2.80 |
| Authors | Studies |
|---|---|
| Hua, H | 1 |
| Zhou, S | 1 |
| Gu, L | 8 |
| Shi, Z | 1 |
| Zhou, B | 1 |
| Wang, J | 4 |
| Wang, Q | 5 |
| Chen, P | 1 |
| Li, Q | 1 |
| Li, Z | 5 |
| Xu, M | 2 |
| Zeng, K | 12 |
| Li, C | 6 |
| Su, Y | 7 |
| Zhang, Y | 10 |
| Tong, Y | 1 |
| Zhang, L | 7 |
| Li, P | 1 |
| Zhang, H | 1 |
| Zhang, X | 2 |
| Tang, Y | 7 |
| Qin, L | 6 |
| Shen, Y | 6 |
| Wang, B | 6 |
| Zhou, Y | 7 |
| Cao, L | 6 |
| Zhang, M | 9 |
| Zhang, T | 7 |
| Hu, R | 1 |
| Romero, MP | 1 |
| Jibaja, I | 1 |
| Bucheli, J | 1 |
| Inada, N | 1 |
| Bagnato, V | 1 |
| Wang, X | 3 |
| You, L | 1 |
| Zhang, W | 2 |
| Ma, Y | 1 |
| Xu, W | 1 |
| Xu, Y | 3 |
| Han, Q | 1 |
| Wu, Z | 1 |
| Guo, H | 1 |
| Cai, H | 2 |
| Che, Y | 2 |
| Sun, X | 1 |
| Yu, X | 1 |
| Yu, F | 1 |
| Hou, F | 1 |
| Wang, Y | 4 |
| Ma, T | 2 |
| Che, Q | 3 |
| Huang, X | 4 |
| Li, J | 6 |
| Jiang, L | 5 |
| Chen, F | 1 |
| Novák, Z | 1 |
| Dannecker, C | 2 |
| Mokráš, C | 1 |
| Sui, L | 1 |
| You, Z | 1 |
| Han, L | 1 |
| Lang, J | 1 |
| Hillemanns, P | 5 |
| Zhou, M | 2 |
| Wang, L | 5 |
| Liu, X | 2 |
| Zhang, J | 3 |
| Jia, L | 3 |
| Hu, Y | 1 |
| Li, Y | 3 |
| Teng, Y | 1 |
| Chen, J | 2 |
| Ma, L | 1 |
| Lu, H | 1 |
| Qu, Z | 1 |
| Wang, Z | 1 |
| Qiu, S | 1 |
| Cui, G | 1 |
| Huang, Y | 2 |
| Liu, Y | 1 |
| Zhang, C | 1 |
| Yuan, S | 1 |
| Huang, J | 1 |
| Wei, Y | 2 |
| Di, W | 3 |
| Hong, Z | 5 |
| Qiu, L | 5 |
| Hu, X | 1 |
| He, Y | 1 |
| Lin, L | 2 |
| Li, X | 2 |
| Luo, X | 1 |
| Xu, C | 1 |
| Chen, Y | 1 |
| Mei, Y | 1 |
| Guo, P | 1 |
| Chen, L | 1 |
| He, D | 1 |
| Hua, C | 1 |
| Zhao, X | 1 |
| Song, S | 1 |
| Mu, X | 1 |
| Hisamatsu, Y | 1 |
| Kita, M | 1 |
| Yokoe, T | 1 |
| Butsuhara, Y | 1 |
| Okada, H | 1 |
| Jiang, S | 1 |
| Nan, X | 1 |
| Pan, X | 1 |
| Tang, L | 1 |
| Gong, H | 1 |
| Liu, H | 6 |
| Wei, J | 1 |
| Zhong, M | 1 |
| Feng, S | 1 |
| Peng, X | 3 |
| Song, W | 1 |
| Zhong, Y | 1 |
| Feng, C | 1 |
| Wu, D | 1 |
| Wu, A | 2 |
| Niu, J | 1 |
| Liang, F | 1 |
| Han, P | 1 |
| Chen, R | 1 |
| Lin, P | 1 |
| Luo, M | 1 |
| Cai, Q | 2 |
| Li, S | 3 |
| Shi, M | 1 |
| Stringasci, MD | 3 |
| Buzzá, HH | 2 |
| de Arruda, SS | 2 |
| Schiavone Crestana, RH | 1 |
| Bagnato, VS | 3 |
| Inada, NM | 3 |
| Yan, L | 1 |
| Ding, Z | 1 |
| Sun, H | 1 |
| de Castro, CA | 2 |
| Lombardi, W | 1 |
| Li, D | 1 |
| Zhang, F | 2 |
| Shi, L | 1 |
| Teng, M | 2 |
| Feng, Y | 2 |
| Xiao, Z | 2 |
| Hu, H | 1 |
| Lu, Y | 1 |
| Yang, B | 1 |
| Cheng, M | 1 |
| Kechichian, E | 1 |
| Helou, E | 1 |
| Sarkis, J | 1 |
| Hayek, C | 1 |
| Labaki, C | 1 |
| Nemr, E | 1 |
| Tomb, R | 1 |
| Cang, W | 1 |
| Hu, Z | 4 |
| Zheng, H | 2 |
| Crestana, RHS | 1 |
| Maldonado Alvarado, E | 1 |
| Osorio Peralta, MO | 1 |
| Moreno Vázquez, A | 1 |
| Martínez Guzmán, LA | 1 |
| Melo Petrone, ME | 1 |
| Enriquez Mar, ZI | 1 |
| Jovel Galdamez, DE | 1 |
| Carrión Solana, B | 1 |
| Balderas Martínez, G | 1 |
| Parra, E | 1 |
| Castellanos Oliveros, RI | 1 |
| Bello Leiva, RL | 1 |
| Espinosa Montesinos, A | 1 |
| Barrera Mendoza, C | 1 |
| Medina García, SE | 1 |
| Ramón Gallegos, E | 1 |
| Liu, L | 2 |
| Meng, X | 1 |
| Shi, X | 1 |
| Luan, H | 1 |
| Liu, W | 1 |
| Hu, S | 1 |
| Yang, Y | 1 |
| Jiang, B | 1 |
| Su, D | 1 |
| Huang, Z | 2 |
| Jin, J | 1 |
| Zhiyue, L | 1 |
| Einstein, MH | 1 |
| Iversen, OE | 1 |
| Fu, Y | 1 |
| Bao, Y | 1 |
| Hui, Y | 1 |
| Gao, X | 1 |
| Yang, M | 1 |
| Chang, J | 1 |
| Soergel, P | 2 |
| Stepp, H | 1 |
| Hertel, H | 1 |
| Wang, HW | 1 |
| Wang, XL | 1 |
| Zhang, LL | 1 |
| Guo, MX | 1 |
| Xu, J | 1 |
| He, Q | 1 |
| Xiang, L | 1 |
| Ding, G | 1 |
| Xu, S | 1 |
| Daayana, S | 1 |
| Winters, U | 1 |
| Stern, PL | 2 |
| Kitchener, HC | 2 |
| Dahl, GF | 1 |
| Onsrud, M | 1 |
| Staehle, S | 1 |
| Michels, W | 1 |
| Wierrani, F | 1 |
| Kubin, A | 1 |
| Jindra, R | 1 |
| Henry, M | 1 |
| Gharehbaghi, K | 1 |
| Grin, W | 1 |
| Söltz-Szötz, J | 1 |
| Alth, G | 1 |
| Grünberger, W | 1 |
| Abdel-Hady, ES | 1 |
| Martin-Hirsch, P | 1 |
| Duggan-Keen, M | 1 |
| Moore, JV | 1 |
| Corbitt, G | 1 |
| Hampson, IN | 1 |
| Szeimies, RM | 1 |
| Landthaler, M | 1 |
| Karrer, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of 5-aminolaevulinic Acid Photodynamic Therapy Versus C02 Laser in the Treatment of Persistent Cervical Low-grade Squamous Intraepithelial Lesions With High-risk HPV Infection:A Non-randomized Controlled Trail Study[NCT06052033] | 40 participants (Anticipated) | Interventional | 2023-09-11 | Recruiting | |||
| A Double Blind, Prospective, Randomized, Placebo Controlled, Multi-center Phase 3 Study to Evaluate Efficacy and Safety of Cevira® in Patients With Cervical Histologic High-grade Squamous Intraepithelial Lesions (HSIL)[NCT04484415] | Phase 3 | 402 participants (Actual) | Interventional | 2020-11-10 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for aminolevulinic acid and HPV Infection
| Article | Year |
|---|---|
Efficacy of non-invasive photodynamic therapy for female lower reproductive tract diseases associated with HPV infection: a comprehensive meta-analysis.
Topics: Aminolevulinic Acid; China; Female; Humans; Papillomavirus Infections; Photochemotherapy; Photosensi | 2023 |
The place of 5-aminolaevulinic acid-photodynamic therapy in the treatment landscape of urethral warts: A systematic review.
Topics: Aminolevulinic Acid; Humans; Neoplasm Recurrence, Local; Papillomavirus Infections; Photochemotherap | 2021 |
Topical hexaminolevulinate photodynamic therapy for the treatment of persistent human papilloma virus infections and cervical intraepithelial neoplasia.
Topics: Aminolevulinic Acid; Female; Humans; Papillomavirus Infections; Photochemotherapy; Photosensitizing | 2015 |
Clinical and immunological response to photodynamic therapy in the treatment of vulval intraepithelial neoplasia.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Female; Humans; Papillomaviridae; Papillomavirus Infections; | 2011 |
Non-oncologic indications for ALA-PDT.
Topics: Aminolevulinic Acid; Humans; Lichen Sclerosus et Atrophicus; Papillomavirus Infections; Photochemoth | 2002 |
9 trials available for aminolevulinic acid and HPV Infection
| Article | Year |
|---|---|
Multicentre, prospective, randomised controlled trial to evaluate hexaminolevulinate photodynamic therapy (Cevira) as a novel treatment in patients with high-grade squamous intraepithelial lesion: APRICITY phase 3 study protocol.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Clinical Trials, Phase III as Topic; Female; Humans; Multice | 2022 |
The effect of aminolevulinic acid hydrochloride topical powder photodynamic therapy versus nocardia rubra cell wall skeleton and observers group in the treatment of cervical low-grade squamous intraepithelial lesions with human papillomavirus infection: A
Topics: Aminolevulinic Acid; Cell Wall Skeleton; Female; Human Papillomavirus Viruses; Humans; Papillomaviru | 2023 |
HPV-induced condylomata acuminata treated by Photodynamic Therapy in comparison with trichloroacetic acid: A randomized clinical trial.
Topics: Aminolevulinic Acid; Brazil; Condylomata Acuminata; Female; Humans; Papillomavirus Infections; Photo | 2021 |
Treatment of condyloma acuminatum using the combination of laser ablation and ALA-PDT.
Topics: Adult; Aminolevulinic Acid; Combined Modality Therapy; Condylomata Acuminata; Female; Humans; Laser | 2019 |
Topical photodynamic therapy with 5-aminolevulinic acid for cervical high-risk HPV infection.
Topics: Administration, Topical; Adult; Aminolevulinic Acid; Female; Humans; Middle Aged; Papillomavirus Inf | 2016 |
Photodynamic therapy of cervical intraepithelial neoplasia with hexaminolevulinate.
Topics: Adult; Aminolevulinic Acid; Feasibility Studies; Female; Humans; Papillomavirus Infections; Photoche | 2008 |
Photodynamic therapy of cervical intraepithelial neoplasia 1-3 and human papilloma virus (HMV) infection with methylaminolevulinate and hexaminolevulinate--a double-blind, dose-finding study.
Topics: Adult; Aminolevulinic Acid; Double-Blind Method; Female; Humans; Papillomavirus Infections; Photoche | 2012 |
5-aminolevulinic acid-mediated photodynamic therapy of intraepithelial neoplasia and human papillomavirus of the uterine cervix--a new experimental approach.
Topics: Administration, Intravaginal; Adolescent; Adult; Aminolevulinic Acid; Combined Modality Therapy; Dru | 1999 |
Treatment of latent or subclinical Genital HPV Infection with 5-aminolevulinic acid-based photodynamic therapy.
Topics: Adult; Aminolevulinic Acid; Asymptomatic Infections; Condylomata Acuminata; Humans; Infant; Levulini | 2018 |
48 other studies available for aminolevulinic acid and HPV Infection
| Article | Year |
|---|---|
Multiple-type HPV infection predicting condyloma acuminatum recurrence after aminolevulinic acid photodynamic therapy.
Topics: Aminolevulinic Acid; Humans; Papillomavirus Infections; Photochemotherapy; Photosensitizing Agents; | 2021 |
Podophyllotoxin-combined 5-aminolevulinic acid photodynamic therapy significantly promotes HR-HPV-infected cell death.
Topics: Aminolevulinic Acid; Apoptosis; Cell Death; Condylomata Acuminata; Humans; Necrosis; Papillomavirus | 2022 |
Effect and rational application of topical photodynamic therapy (PDT) with 5-aminolevulinic acid (5-ALA) for treatment of cervical intraepithelial neoplasia with vaginal intraepithelial neoplasia.
Topics: Aminolevulinic Acid; Female; Human papillomavirus 16; Human papillomavirus 18; Humans; Papillomaviru | 2022 |
The effect of local photodynamic therapy with 5-aminolevulinic acid in the treatment of vaginal intraepithelial lesions with high-risk HPV infection.
Topics: Aminolevulinic Acid; Female; Human papillomavirus 16; Human papillomavirus 18; Humans; Neoplasm Recu | 2022 |
Clinical study of anogenital condyloma acuminata treatment with photodynamic therapy including immunocompromised conditions.
Topics: Aminolevulinic Acid; Condylomata Acuminata; Humans; Papillomavirus Infections; Photochemotherapy; Ph | 2022 |
Evaluation of 5-aminolevulinic acid-mediated photodynamic therapy on cervical low-grade squamous intraepithelial lesions with high-risk HPV infection.
Topics: Aminolevulinic Acid; Cervix Uteri; Ectropion; Female; Humans; Papillomavirus Infections; Photochemot | 2022 |
Therapeutic effects of topical photodynamic therapy with 5-aminolevulinic acid on cervical high-grade squamous intraepithelial lesions.
Topics: Adolescent; Adult; Aminolevulinic Acid; Carcinoma, Squamous Cell; Female; Humans; Middle Aged; Papil | 2022 |
Efficacy and safety of photodynamic therapy mediatied by 5-aminolevulinic acid for the treatment of vaginal high-grade intraepithelial lesions.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Female; Humans; Papillomaviridae; Papillomavirus Infections; | 2022 |
Clinical outcome of photodynamic therapy for the treatment of cervical intraepithelial neoplasia grade 2.
Topics: Aminolevulinic Acid; Female; Humans; Papillomavirus Infections; Photochemotherapy; Photosensitizing | 2022 |
Effectiveness of photodynamic therapy with 5-aminolevulinic acid for Bowenoid papulosis: A retrospective study with long-term follow-up.
Topics: Adolescent; Aminolevulinic Acid; Carcinoma, Squamous Cell; Condylomata Acuminata; Follow-Up Studies; | 2022 |
Comparative study of topical 5-aminolevulinic acid photodynamic therapy (5-ALA-PDT) and surgery for the treatment of high-grade vaginal intraepithelial neoplasia.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Female; Humans; Middle Aged; Papillomavirus Infections; Phot | 2022 |
The effect of high-risk HPV E6/E7 mRNA on the efficacy of topical photodynamic therapy with 5-aminolevulinic acid for cervical high-grade squamous intraepithelial lesions.
Topics: Aminolevulinic Acid; Female; Human papillomavirus 16; Human papillomavirus 18; Humans; Neoplasm Recu | 2022 |
Management of patients with positive margin after conization for high-grade cervical intraepithelial lesions.
Topics: Aminolevulinic Acid; Conization; Female; Humans; Margins of Excision; Neoplasm Recurrence, Local; Pa | 2022 |
Evaluation of 5-aminolevulinic acid-mediated photodynamic therapy in postmenopausal women with persistent HPV infection with or without cervical and vaginal low-grade squamous intraepithelial lesions (CIN1/VaIN1).
Topics: Aminolevulinic Acid; Female; Humans; Papillomaviridae; Papillomavirus Infections; Photochemotherapy; | 2022 |
Topical 5-aminolevulinic acid photodynamic therapy for cervical high-grade squamous intraepithelial lesions.
Topics: Aminolevulinic Acid; Female; Humans; Papillomaviridae; Papillomavirus Infections; Photochemotherapy; | 2022 |
Enhancement of the cytotoxic effect of dihydroartemisinin in high-risk human papillomavirus-infected cells by aminolevulinic acid via the Bax/Bcl-2-caspase pathway.
Topics: Aminolevulinic Acid; Apoptosis; Caspases; Cell Line, Tumor; HeLa Cells; Heme; Human Papillomavirus V | 2022 |
Efficacy of photodynamic therapy with 5-aminolevulinic acid for the treatment of cervical high-grade squamous intraepithelial lesions with high-risk HPV infection: A retrospective study.
Topics: Aminolevulinic Acid; Female; Humans; Papillomavirus Infections; Photochemotherapy; Retrospective Stu | 2022 |
Evaluation of the efficacy and safety of 5-aminolevulinic acid-mediated photodynamic therapy in women with high-risk HPV persistent infection after cervical conization.
Topics: Aminolevulinic Acid; Conization; Female; Human papillomavirus 16; Human papillomavirus 18; Humans; M | 2022 |
The effect of local photodynamic therapy with 5-aminolevulinic acid in treating different grades of cervical intraepithelial neoplasia.
Topics: Aminolevulinic Acid; Female; Humans; Neoplasm Recurrence, Local; Papillomavirus Infections; Photoche | 2022 |
Feasibility study of 5-aminolevulinic acid mediated photodynamic therapy of persistent vaginal high-risk HPV infection of post-hysterectomy patients.
Topics: Adult; Aged; Aminolevulinic Acid; Feasibility Studies; Female; Humans; Hysterectomy; Middle Aged; Pa | 2023 |
5-aminolevulinic acid photodynamic therapy combined with carbon dioxide laser therapy is a safe and effective treatment for vaginal intraepithelial neoplasia.
Topics: Aminolevulinic Acid; Carbon Dioxide; Carcinoma in Situ; Female; Humans; Laser Therapy; Lasers, Gas; | 2023 |
A novel PDT: 5-aminolevulinic acid combined 450 nm blue laser photodynamic therapy significantly promotes cell death of HR-HPV infected cells.
Topics: Aminolevulinic Acid; Apoptosis; Cell Death; Cell Line, Tumor; HeLa Cells; Human Papillomavirus Virus | 2023 |
Effects of photodynamic therapy in the treatment of high-grade vaginal intraepithelial lesions following hysterectomy and HPV infection.
Topics: Aminolevulinic Acid; Female; Humans; Hysterectomy; Papillomavirus Infections; Photochemotherapy; Pho | 2023 |
A pilot study of repeated 5-aminolevulinic acid photodynamic therapy for cervical intraepithelial neoplasia by a newly developed intravaginal irradiation system.
Topics: Aminolevulinic Acid; Female; Humans; Papillomavirus Infections; Photochemotherapy; Photosensitizing | 2023 |
Evaluation of HPV infection helps to direct ALA-PDT of condyloma acuminata.
Topics: Aminolevulinic Acid; Condylomata Acuminata; DNA; Humans; Papillomaviridae; Papillomavirus Infections | 2023 |
Effect of topical 5-aminolevulinic acid photodynamic therapy versus therapy combined with CO2 laser pretreatment for patients with cervical high-grade squamous intraepithelial lesions.
Topics: Aminolevulinic Acid; Human papillomavirus 16; Human papillomavirus 18; Humans; Lasers, Gas; Papillom | 2023 |
The effects of 5-aminolevulinic acid photodynamic therapy on the local immune response of women with cervical intraepithelial neoplasia grade 2.
Topics: Aminolevulinic Acid; CD8-Positive T-Lymphocytes; Female; Humans; Papillomavirus Infections; Photoche | 2023 |
Topical 5-aminolevulinic acid photodynamic therapy for laryngeal papillomatosistosis treatment.
Topics: Administration, Topical; Adult; Aminolevulinic Acid; Child; Child, Preschool; Female; Humans; Infant | 2019 |
Evaluation of human papillomavirus DNA detection-guided aminolaevulinic acid-mediated photodynamic therapy for the treatment of condyloma acuminata.
Topics: Adolescent; Adult; Aged; Aminolevulinic Acid; Condylomata Acuminata; DNA, Viral; Female; Humans; Mal | 2019 |
HPV condylomatosis region treated with multiple sessions of MAL-PDT: A case report.
Topics: Aminolevulinic Acid; Humans; Papillomavirus Infections; Photochemotherapy; Photosensitizing Agents | 2020 |
Application of 5-aminolevulinic acid photodynamic therapy for vaginal intraepithelial neoplasia, a report of six cases.
Topics: Aminolevulinic Acid; Female; Humans; Middle Aged; Neoplasm Recurrence, Local; Papillomavirus Infecti | 2020 |
High-risk HPV clearance and CIN 3 treated with MAL-PDT: A case report.
Topics: Adult; Aminolevulinic Acid; Female; Humans; Neoplasm Recurrence, Local; Papillomavirus Infections; P | 2020 |
Treatment of HPV Infection-Associated Low Grade Cervical Intraepithelial Neoplasia with 5-Aminolevulinic Acid-Mediated Photodynamic Therapy.
Topics: Adult; Aminolevulinic Acid; Female; Humans; Papillomavirus Infections; Photochemotherapy; Photosensi | 2020 |
Dihydroartemisinin administration improves the effectiveness of 5-aminolevulinic acid-mediated photodynamic therapy for the treatment of high-risk human papillomavirus infection.
Topics: Aminolevulinic Acid; Apoptosis; Artemisinins; Cell Line, Tumor; Female; HeLa Cells; Humans; Papillom | 2021 |
The effect of local photodynamic therapy with 5-aminolevulinic acid for the treatment of cervical low-grade squamous intraepithelial lesions with high-risk HPV infection: A retrospective study.
Topics: Adult; Aged; Aminolevulinic Acid; Female; Human papillomavirus 16; Human papillomavirus 18; Humans; | 2021 |
The mechanism of 5-aminolevulinic acid photodynamic therapy in promoting endoplasmic reticulum stress in the treatment of HR-HPV-infected HeLa cells.
Topics: Aminolevulinic Acid; AMP-Activated Protein Kinases; Apoptosis; Calcium; Calcium-Calmodulin-Dependent | 2021 |
Effectiveness of photodynamic therapy with 5-aminolevulinic acid on HPV clearance in women without cervical lesions.
Topics: Aminolevulinic Acid; Female; Human papillomavirus 16; Human papillomavirus 18; Humans; Papillomaviru | 2021 |
Predictors of human papillomavirus persistence or clearance after 5-aminolevulinic acid-based photodynamic therapy in patients with genital warts.
Topics: Alphapapillomavirus; Aminolevulinic Acid; Condylomata Acuminata; Humans; Papillomaviridae; Papilloma | 2021 |
Patterns of multiple human papillomavirus clearance during 5-aminolevulinic acid-based photodynamic therapy in patients with genital warts.
Topics: Alphapapillomavirus; Aminolevulinic Acid; Condylomata Acuminata; Humans; Papillomaviridae; Papilloma | 2021 |
Effectiveness of Photodynamic Therapy in Elimination of HPV-16 and HPV-18 Associated with CIN I in Mexican Women.
Topics: Adult; Aminolevulinic Acid; Female; Human papillomavirus 16; Human papillomavirus 18; Humans; Mexico | 2017 |
Dynamics of HPV viral loads reflect the treatment effect of photodynamic therapy in genital warts.
Topics: Adult; Aminolevulinic Acid; Condylomata Acuminata; Female; Genotype; Humans; Male; Middle Aged; Papi | 2018 |
LEEP/Cone combined with photodynamic therapy for successful treatment of high-grade squamous intraepithelial lesion.
Topics: Adult; Aminolevulinic Acid; Combined Modality Therapy; Conization; Electrosurgery; Female; Humans; P | 2019 |
Human papillomavirus DNA detection-guided ALA-photodynamic therapy for anogenital condyloma acuminata: A report of two cases.
Topics: Adult; Aminolevulinic Acid; Condylomata Acuminata; DNA, Viral; Genotype; Humans; Lasers, Gas; Male; | 2019 |
Successful treatment of oral human papilloma by local injection 5-aminolevulinic acid-mediated photodynamic therapy: A case report.
Topics: Aminolevulinic Acid; Humans; Male; Middle Aged; Mouth; Papillomavirus Infections; Photochemotherapy; | 2019 |
Aminolevulinic acid (ALA)-assisted photodynamic diagnosis of subclinical and latent HPV infection of external genital region.
Topics: Adult; Aminolevulinic Acid; Condylomata Acuminata; Dermoscopy; Female; Humans; Image Enhancement; Ma | 2008 |
Successful photodynamic therapy with topical 5-aminolevulinic acid for five cases of cervical intraepithelial neoplasia.
Topics: Administration, Topical; Adult; Aminolevulinic Acid; Female; Humans; Middle Aged; Papillomavirus Inf | 2010 |
Evaluation of different treatment modalities for vulvar intraepithelial neoplasia (VIN): CO(2) laser vaporization, photodynamic therapy, excision and vulvectomy.
Topics: Adult; Aminolevulinic Acid; Carcinoma in Situ; Female; Gynecologic Surgical Procedures; Humans; Lase | 2006 |
Immunological and viral factors associated with the response of vulval intraepithelial neoplasia to photodynamic therapy.
Topics: Adolescent; Adult; Aged; Aminolevulinic Acid; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes | 2001 |