aminolevulinic acid has been researched along with Fifth Phacomatosis in 17 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
| Excerpt | Relevance | Reference |
|---|---|---|
| " To prevent treatment discomfort, analgesics and/or cooling by sprayed water were most often provided, and occasionally 1% lidocaine local anesthesia." | 3.79 | Treatment of Gorlin syndrome (nevoid basal cell carcinoma syndrome) with methylaminolevulinate photodynamic therapy in seven patients, including two children: interest of tumescent anesthesia for pain control in children. ( Bessis, D; Blatière, V; Debu, A; Dereure, O; Girard, C; Guillot, B, 2013) |
| "No new basal cell carcinomas were observed during the 8-month follow-up period in areas treated with a broad application technique." | 2.42 | delta-Aminolevulinic acid and blue light photodynamic therapy for treatment of multiple basal cell carcinomas in two patients with nevoid basal cell carcinoma syndrome. ( Gilchrest, BA; Itkin, A, 2004) |
| "Patients with nevoid basal cell carcinoma syndrome suffer from multiple basal cell carcinomas, requiring numerous surgical procedures that over time leave them with multiple disfiguring scars." | 2.42 | delta-Aminolevulinic acid and blue light photodynamic therapy for treatment of multiple basal cell carcinomas in two patients with nevoid basal cell carcinoma syndrome. ( Gilchrest, BA; Itkin, A, 2004) |
| "We report treatment of two nevoid basal cell carcinoma syndrome patients, women aged 21 and 47, with 20%delta-aminolevulinic acid solution and 417-nm blue light source (irradiance 10 mW/cm(2))." | 2.42 | delta-Aminolevulinic acid and blue light photodynamic therapy for treatment of multiple basal cell carcinomas in two patients with nevoid basal cell carcinoma syndrome. ( Gilchrest, BA; Itkin, A, 2004) |
| "Patients with Gorlin syndrome develop multiple basal cell carcinomas (BCC), for which treatment is often difficult." | 1.40 | Consensus recommendations for the treatment of basal cell carcinomas in Gorlin syndrome with topical methylaminolaevulinate-photodynamic therapy. ( Basset-Seguin, N; Bissonnette, R; Girard, C; Haedersdal, M; Lear, JT; Paul, C; Piaserico, S, 2014) |
| " For laser treatments, a sigmoidal light dose-response relationship predicted more than 85% initial response rates for light doses 150 J/cm(2) or more." | 1.33 | Treatment of diffuse basal cell carcinomas and basaloid follicular hamartomas in nevoid basal cell carcinoma syndrome by wide-area 5-aminolevulinic acid photodynamic therapy. ( Bellnier, DA; Blumenson, LE; Cheney, R; Frawley, NP; Oseroff, AR; Pivnick, EK; Shieh, S, 2005) |
| "Exclusion of unilateral nevoid basal cell carcinoma syndrome is indicated." | 1.33 | Unilateral Basal cell carcinomas: an unusual entity treated with photodynamic therapy. ( Allen, JH; Lane, JE; Lane, TN; Lesher, JL, 2005) |
| "Like nevoid basal cell carcinoma syndrome, unilateral basal cell carcinomas poses a therapeutic challenge with the sheer number of cutaneous tumors." | 1.33 | Unilateral Basal cell carcinomas: an unusual entity treated with photodynamic therapy. ( Allen, JH; Lane, JE; Lane, TN; Lesher, JL, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 7 (41.18) | 29.6817 |
| 2010's | 6 (35.29) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Thompson, A | 1 |
| Mattia, A | 1 |
| Green, WH | 2 |
| Cognetta, AB | 2 |
| Li, C | 1 |
| Chen, P | 1 |
| Li, Z | 1 |
| Wang, Y | 1 |
| He, S | 1 |
| Shi, M | 1 |
| Wang, Q | 1 |
| Xu, M | 1 |
| Li, Q | 1 |
| Chen, H | 1 |
| Zeng, K | 1 |
| Liang, J | 1 |
| Zhang, X | 1 |
| Maytin, EV | 1 |
| Kaw, U | 1 |
| Ilyas, M | 1 |
| Mack, JA | 1 |
| Hu, B | 1 |
| Basset-Seguin, N | 3 |
| Bissonnette, R | 2 |
| Girard, C | 2 |
| Haedersdal, M | 1 |
| Lear, JT | 1 |
| Paul, C | 2 |
| Piaserico, S | 1 |
| Miguélez, A | 1 |
| Martín-Santiago, A | 1 |
| Bauzá, A | 1 |
| Gilaberte, Y | 1 |
| Mougel, F | 1 |
| Debarbieux, S | 1 |
| Ronger-Savlé, S | 1 |
| Dalle, S | 1 |
| Thomas, L | 1 |
| Gilchrest, BA | 2 |
| Brightman, LA | 1 |
| Thiele, JJ | 1 |
| Wasserman, DI | 1 |
| Pauwels, C | 1 |
| Mazereeuw-Hautier, J | 1 |
| Livideanu, C | 1 |
| Viraben, R | 1 |
| Meyer, N | 1 |
| Debu, A | 1 |
| Bessis, D | 1 |
| Blatière, V | 1 |
| Dereure, O | 1 |
| Guillot, B | 1 |
| Wolfe, CM | 1 |
| Hatfield, HK | 1 |
| Haylett, AK | 1 |
| Ward, TH | 1 |
| Moore, JV | 1 |
| Itkin, A | 1 |
| Oseroff, AR | 1 |
| Shieh, S | 1 |
| Frawley, NP | 1 |
| Cheney, R | 1 |
| Blumenson, LE | 1 |
| Pivnick, EK | 1 |
| Bellnier, DA | 1 |
| Lane, JE | 1 |
| Allen, JH | 1 |
| Lane, TN | 1 |
| Lesher, JL | 1 |
| Braathen, LR | 1 |
| Szeimies, RM | 2 |
| Foley, P | 1 |
| Pariser, D | 1 |
| Roelandts, R | 1 |
| Wennberg, AM | 1 |
| Morton, CA | 1 |
| Wolf, P | 1 |
| Kerl, H | 1 |
| Karrer, S | 1 |
| Hohenleutner, U | 1 |
| Heine, A | 1 |
| Landthaler, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Formulation of 5-aminolevulinic Acid With Dimethylsulfoxide in Photodynamic Therapy for Treatment of Actinic Keratosis[NCT01459393] | Phase 3 | 137 participants (Actual) | Interventional | 2010-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for aminolevulinic acid and Fifth Phacomatosis
| Article | Year |
|---|---|
delta-Aminolevulinic acid and blue light photodynamic therapy for treatment of multiple basal cell carcinomas in two patients with nevoid basal cell carcinoma syndrome.
Topics: Adult; Aminolevulinic Acid; Basal Cell Nevus Syndrome; Carcinoma, Basal Cell; Female; Humans; Middle | 2004 |
Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: an international consensus. International Society for Photodynamic Therapy in Dermatology, 2005.
Topics: Aminolevulinic Acid; Australia; Basal Cell Nevus Syndrome; Bowen's Disease; Carcinoma, Basal Cell; C | 2007 |
1 trial available for aminolevulinic acid and Fifth Phacomatosis
| Article | Year |
|---|---|
Blue light versus red light for photodynamic therapy of basal cell carcinoma in patients with Gorlin syndrome: A bilaterally controlled comparison study.
Topics: Adult; Aminolevulinic Acid; Basal Cell Nevus Syndrome; Carcinoma, Basal Cell; Female; Humans; Light; | 2018 |
14 other studies available for aminolevulinic acid and Fifth Phacomatosis
| Article | Year |
|---|---|
A 10-year follow-up on the chemopreventive role of photodynamic therapy in a Gorlin syndrome patient.
Topics: Aminolevulinic Acid; Basal Cell Nevus Syndrome; Carcinoma, Basal Cell; Follow-Up Studies; Humans; Ph | 2022 |
5-aminolevulinic acid photodynamic therapy and excision surgery for nevoid basal cell carcinoma syndrome with multiple basal cell carcinomas and PTCH1 mutation.
Topics: Aminolevulinic Acid; Basal Cell Nevus Syndrome; Carcinoma, Basal Cell; Hamartoma Syndrome, Multiple; | 2020 |
Consensus recommendations for the treatment of basal cell carcinomas in Gorlin syndrome with topical methylaminolaevulinate-photodynamic therapy.
Topics: Administration, Topical; Adult; Aged; Aminolevulinic Acid; Basal Cell Nevus Syndrome; Carcinoma, Bas | 2014 |
Urticaria-like reaction secondary to photodynamic therapy in 2 pediatric patients.
Topics: Aminolevulinic Acid; Basal Cell Nevus Syndrome; Child; Child, Preschool; Female; Humans; Neoplasms, | 2013 |
Methylaminolaevulinate photodynamic therapy in patients with multiple basal cell carcinomas in the setting of Gorlin-Goltz syndrome or after radiotherapy.
Topics: Adult; Aged; Aminolevulinic Acid; Basal Cell Nevus Syndrome; Cohort Studies; Combined Modality Thera | 2009 |
Photodynamic therapy for patients with Basal cell nevus syndrome.
Topics: Aged; Aminolevulinic Acid; Basal Cell Nevus Syndrome; Female; Humans; Male; Middle Aged; Photochemot | 2009 |
Topical methyl aminolevulinate photodynamic therapy for management of basal cell carcinomas in patients with basal cell nevus syndrome improves patient's satisfaction and reduces the need for surgical procedures.
Topics: Aminolevulinic Acid; Basal Cell Nevus Syndrome; Humans; Patient Satisfaction; Photochemotherapy; Ski | 2011 |
Treatment of Gorlin syndrome (nevoid basal cell carcinoma syndrome) with methylaminolevulinate photodynamic therapy in seven patients, including two children: interest of tumescent anesthesia for pain control in children.
Topics: Adolescent; Adult; Aminolevulinic Acid; Anesthesia; Basal Cell Nevus Syndrome; Child; Female; Humans | 2013 |
Urticaria after methyl aminolevulinate photodynamic therapy in a patient with nevoid basal cell carcinoma syndrome.
Topics: Aminolevulinic Acid; Basal Cell Nevus Syndrome; Carcinoma, Basal Cell; Female; Humans; Middle Aged; | 2012 |
DNA damage and repair in Gorlin syndrome and normal fibroblasts after aminolevulinic acid photodynamic therapy: a comet assay study.
Topics: Aminolevulinic Acid; Basal Cell Nevus Syndrome; Cell Survival; Comet Assay; DNA Damage; DNA Repair; | 2003 |
Treatment of diffuse basal cell carcinomas and basaloid follicular hamartomas in nevoid basal cell carcinoma syndrome by wide-area 5-aminolevulinic acid photodynamic therapy.
Topics: Adolescent; Aminolevulinic Acid; Basal Cell Nevus Syndrome; Child; Female; Hamartoma Syndrome, Multi | 2005 |
Unilateral Basal cell carcinomas: an unusual entity treated with photodynamic therapy.
Topics: Aminolevulinic Acid; Basal Cell Nevus Syndrome; Carcinoma, Basal Cell; Diagnosis, Differential; Foll | 2005 |
Photodynamic therapy with 5-aminolevulinic acid: a promising concept for the treatment of cutaneous tumors.
Topics: Administration, Cutaneous; Aged; Aminolevulinic Acid; Basal Cell Nevus Syndrome; Female; Humans; Las | 1995 |
Unilateral localized basaliomatosis: treatment with topical photodynamic therapy after application of 5-aminolevulinic acid.
Topics: Administration, Cutaneous; Aged; Aminolevulinic Acid; Basal Cell Nevus Syndrome; Carcinoma, Basal Ce | 1995 |