Page last updated: 2024-10-16

aminolevulinic acid and Facial Neoplasms

aminolevulinic acid has been researched along with Facial Neoplasms in 30 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Facial Neoplasms: New abnormal growth of tissue in the FACE.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study is to investigate the clinical efficacy of Mohs surgery in combination with topical photodynamic therapy (PDT) for facial basal cell carcinoma."1.56Clinical efficacy of Mohs surgery combined with topical photodynamic therapy for facial basal cell carcinoma. ( Kou, H; Lu, Y; Wang, Y; Yang, Y; Zhang, J; Zhang, X, 2020)
"The facial angiofbromas due to tuberous sclerosis complex produced significant social and emotional distress for affected individuals, but there is no specific therapeutic strategy up to now."1.51Photodynamic therapy in a patient with facial angiofibromas due to tuberous sclerosis complex. ( Chen, P; Guo, J; He, S; Jiang, L; Li, C; Li, Q; Li, S; Peng, X; Shi, M; Wang, Q; Zeng, K; Zhu, M, 2019)
"Referral skin cancer centre in Australia."1.42Post procedural pain with photodynamic therapy is more severe than skin surgery. ( Anderson, SJ; Dixon, AJ; Dixon, JB; Dixon, MP, 2015)
"Cutaneous squamous cell carcinoma (cSCC) usually has ill-defined margins because of its irregular invasive patterns."1.39Efficacy of photodynamic diagnosis-guided Mohs micrographic surgery in primary squamous cell carcinoma. ( Jeon, SY; Kim, KH; Song, KH, 2013)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (13.33)18.2507
2000's6 (20.00)29.6817
2010's19 (63.33)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Shi, M1
He, S1
Chen, P1
Li, Q2
Zhu, M1
Guo, J1
Jiang, L1
Wang, Q1
Peng, X1
Li, S1
Li, C2
Zeng, K1
Zhang, J1
Lu, Y1
Zhang, X2
Yang, Y1
Kou, H1
Wang, Y1
Vrani, F1
Sotiriou, E2
Lazaridou, E1
Vakirlis, E1
Sideris, N1
Kirmanidou, E1
Apalla, Z2
Lallas, A1
Ioannides, D2
Dixon, AJ2
Anderson, SJ2
Dixon, MP1
Dixon, JB1
Jeon, SY1
Kim, KH1
Song, KH1
Mazzurco, JD1
Steinman, HK1
Liang, WM1
Theng, TS1
Lim, KS1
Tan, WP1
Haak, CS1
Togsverd-Bo, K1
Thaysen-Petersen, D1
Wulf, HC2
Paasch, U1
Anderson, RR1
Haedersdal, M1
Kluger, N2
Jeskanen, L1
Höök-Nikanne, J1
Weinberger, CH1
Endrizzi, B1
Hook, KP1
Lee, PK1
Chovarda, E1
Lefaki, I1
Devliotou-Panagiotidou, D1
Debu, A1
Girard, C1
Guillot, B1
Dereure, O1
Xia, Y1
Xu, S1
Liu, X1
Chen, AC1
Gao, T1
Jiao, B1
Hu, X1
Luan, Q1
Li, K1
Ma, C1
Wang, S1
Torres, T1
Fernandes, I1
Costa, V1
Selores, M1
Szeimies, RM2
Torezan, L1
Niwa, A1
Valente, N1
Unger, P1
Kohl, E1
Schreml, S1
Babilas, P1
Karrer, S2
Festa-Neto, C1
Chen, J1
Luo, Y1
Zhang, L1
Luo, R1
Li, L1
Requena, C1
Messeguer, F1
Llombart, B1
Serra-Guillén, C1
Guillén, C1
Goldberg, LH1
Landau, JM1
Moody, MN1
Marquez, D1
Jih, M1
Kimyai-Asadi, A1
Friedman, PM1
Busch, A1
Vergilis-Kalner, IJ1
Morton, CA2
Wiegell, SR1
Skødt, V1
Ericson, MB2
Sandberg, C1
Gudmundson, F1
Rosén, A2
Larkö, O2
Wennberg, AM2
Schleier, P1
Hyckel, P1
Berndt, A1
Bode, HP1
Albrecht, V1
Hindermann, W1
Kosmehl, H1
Zenk, W1
Schumann, D1
Stenquist, B1
Strandeberg, C1
Mölne, L1
Won, Y1
Hong, SH1
Yu, HY1
Kwon, YH1
Yun, SJ1
Lee, SC1
Lee, JB1
Calzavara-Pinton, PG1
Orenstein, A1
Kostenich, G1
Tsur, H1
Kogan, L1
Malik, Z1
Lang, S1
Baumgartner, R1
Struck, R1
Leunig, A1
Gutmann, R1
Feyh, J1
Abels, C1
Wlotzke, U1
Stolz, W1
Landthaler, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Aminolevulinic Acid-photodynamic Therapy for Facial Actinic Keratosis Treatment and Prevention: A Long-term (3 Years) Follow-up of Prospective, Randomized, Multicenter-clinical Trial[NCT03642535]Phase 4300 participants (Anticipated)Interventional2018-08-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

7 trials available for aminolevulinic acid and Facial Neoplasms

ArticleYear
Short incubation fractional CO
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2019, Volume: 33, Issue:1

    Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Carc

2019
Novel photodynamic therapy does not prevent new skin cancers--randomized controlled trial.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2014, Volume: 40, Issue:4

    Topics: Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Facial Neoplasms; Female

2014
Fractional laser-mediated photodynamic therapy of high-risk basal cell carcinomas--a randomized clinical trial.
    The British journal of dermatology, 2015, Volume: 172, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Combined Modality Therap

2015
Skin cancer: preventive photodynamic therapy in patients with face and scalp cancerization. A randomized placebo-controlled study.
    The British journal of dermatology, 2010, Volume: 162, Issue:1

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Facia

2010
Clinical, histopathological and immunohistochemical assessment of human skin field cancerization before and after photodynamic therapy.
    The British journal of dermatology, 2012, Volume: 167, Issue:1

    Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Clinical Protocols;

2012
Fluorescence contrast and threshold limit: implications for photodynamic diagnosis of basal cell carcinoma.
    Journal of photochemistry and photobiology. B, Biology, 2003, Volume: 69, Issue:2

    Topics: Administration, Topical; Aminolevulinic Acid; Carcinoma, Basal Cell; Facial Neoplasms; Humans; Image

2003
Repetitive photodynamic therapy with topical delta-aminolaevulinic acid as an appropriate approach to the routine treatment of superficial non-melanoma skin tumours.
    Journal of photochemistry and photobiology. B, Biology, 1995, Volume: 29, Issue:1

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell;

1995

Other Studies

23 other studies available for aminolevulinic acid and Facial Neoplasms

ArticleYear
Photodynamic therapy in a patient with facial angiofibromas due to tuberous sclerosis complex.
    Photodiagnosis and photodynamic therapy, 2019, Volume: 28

    Topics: Adolescent; Aminolevulinic Acid; Angiofibroma; Facial Neoplasms; Humans; Male; Microwaves; Photochem

2019
Clinical efficacy of Mohs surgery combined with topical photodynamic therapy for facial basal cell carcinoma.
    Journal of cancer research and therapeutics, 2020, Volume: 16, Issue:5

    Topics: Adult; Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Combined Modality Therapy; Facial Neoplasms

2020
Post procedural pain with photodynamic therapy is more severe than skin surgery.
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2015, Volume: 68, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Analgesics; Facial Neoplasms; Female; Humans; M

2015
Efficacy of photodynamic diagnosis-guided Mohs micrographic surgery in primary squamous cell carcinoma.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2013, Volume: 39, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma, Squamous Cell; Facial Neopla

2013
Rapid development of squamous cell carcinoma after photodynamic therapy.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2014, Volume: 40, Issue:5

    Topics: Aged; Aminolevulinic Acid; Bowen's Disease; Carcinoma, Squamous Cell; Disease Progression; Facial Ne

2014
Photodynamic therapy-triggered bullous pemphigoid.
    International journal of dermatology, 2017, Volume: 56, Issue:2

    Topics: Aged, 80 and over; Aminolevulinic Acid; Bowen's Disease; Drug Eruptions; Facial Neoplasms; Humans; M

2017
Treatment of angiofibromas of tuberous sclerosis with 5-aminolevulinic acid blue light photodynamic therapy followed by immediate pulsed dye laser.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2009, Volume: 35, Issue:11

    Topics: Adolescent; Adult; Aminolevulinic Acid; Angiofibroma; Child; Combined Modality Therapy; Facial Neopl

2009
Topical methyl aminolaevulinate-photodynamic therapy in erosive facial mycosis fungoides.
    The British journal of dermatology, 2010, Volume: 163, Issue:4

    Topics: Aged, 80 and over; Aminolevulinic Acid; Facial Neoplasms; Humans; Male; Mycosis Fungoides; Photochem

2010
Photodynamic therapy as consolidation treatment for primary cutaneous adenoid cystic carcinoma: a case report.
    Photomedicine and laser surgery, 2010, Volume: 28, Issue:5

    Topics: Administration, Topical; Aminolevulinic Acid; Biopsy, Needle; Carcinoma, Adenoid Cystic; Chemotherap

2010
Tumor thickness predicts long-term complete response of facial basal cell carcinomas in Asian skin types iv/v treated with methyl aminolaevulinate photodynamic therapy.
    Photomedicine and laser surgery, 2011, Volume: 29, Issue:7

    Topics: Aminolevulinic Acid; Biopsy; Carcinoma, Basal Cell; Chi-Square Distribution; China; Facial Neoplasms

2011
Photodynamic therapy as adjunctive therapy for morpheaform basal cell carcinoma.
    Acta dermatovenerologica Alpina, Pannonica, et Adriatica, 2011, Volume: 20, Issue:1

    Topics: Aminolevulinic Acid; Carcinoma, Basal Cell; Chemotherapy, Adjuvant; Chromosomes, Artificial, Bacteri

2011
Fluorescence examination and photodynamic therapy of facial squamous cell carcinoma--a case report.
    Photodiagnosis and photodynamic therapy, 2012, Volume: 9, Issue:1

    Topics: Aged; Aminolevulinic Acid; Facial Neoplasms; Hematoporphyrins; Humans; Male; Neoplasms, Squamous Cel

2012
Facial extensive recurrent basal cell carcinoma: successful treatment with photodynamic therapy and imiquimod 5% cream.
    International journal of dermatology, 2012, Volume: 51, Issue:4

    Topics: Aged, 80 and over; Aminolevulinic Acid; Aminoquinolines; Antineoplastic Agents; Carcinoma, Basal Cel

2012
Evaluation of the chemopreventative effects of ALA PDT in patients with multiple actinic keratoses and a history of skin cancer.
    Journal of drugs in dermatology : JDD, 2012, Volume: 11, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Facial Neoplasms; Female; Follow-Up Studies; He

2012
Can photodynamic therapy reverse the signs of photoageing and field cancerization?
    The British journal of dermatology, 2012, Volume: 167, Issue:1

    Topics: Aminolevulinic Acid; Facial Neoplasms; Female; Humans; Keratosis, Actinic; Male; Photochemotherapy;

2012
Daylight-mediated photodynamic therapy of basal cell carcinomas - an explorative study.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2014, Volume: 28, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Back; Carcinoma, Basal Cell; Facial Neoplasms;

2014
Photodynamic therapy of virus-associated epithelial tumours of the face in organ transplant recipients.
    Journal of cancer research and clinical oncology, 2004, Volume: 130, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Facial Neoplasms; Humans; Keratosis

2004
Bispectral fluorescence imaging of aggressive basal cell carcinoma combined with histopathological mapping: a preliminary study indicating a possible adjunct to Mohs micrographic surgery.
    The British journal of dermatology, 2006, Volume: 154, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Facial Neoplasms; Female

2006
Photodetection of basal cell carcinoma using methyl 5-aminolaevulinate-induced protoporphyrin IX based on fluorescence image analysis.
    Clinical and experimental dermatology, 2007, Volume: 32, Issue:4

    Topics: Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Facial Neoplasms; Female; Humans; Male; Middle Age

2007
Temperature monitoring during photodynamic therapy of skin tumors with topical 5-aminolevulinic acid application.
    Cancer letters, 1995, Jul-13, Volume: 93, Issue:2

    Topics: Aminolevulinic Acid; Body Temperature; Carcinoma, Basal Cell; Facial Dermatoses; Facial Neoplasms; H

1995
[Photodynamic diagnosis and therapy of neoplasms of the facial skin after topical administration of 5-aminolevulinic acid].
    Laryngo- rhino- otologie, 1995, Volume: 74, Issue:2

    Topics: Administration, Topical; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Facial

1995
Epidermodysplasia verruciformis treated using topical 5-aminolaevulinic acid photodynamic therapy.
    The British journal of dermatology, 1999, Volume: 140, Issue:5

    Topics: Administration, Topical; Aged; Aminolevulinic Acid; Arm; DNA, Viral; Epidermodysplasia Verruciformis

1999
Topical photodynamic therapy in dermatology.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2001, Volume: 91, Issue:8

    Topics: Administration, Topical; Aminolevulinic Acid; Facial Neoplasms; Hematoporphyrin Photoradiation; Huma

2001