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aminolevulinic acid and Experimental Leukemia

aminolevulinic acid has been researched along with Experimental Leukemia in 7 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Research Excerpts

ExcerptRelevanceReference
"By determining cell viability using tetrazolium salt reduction (MTT), by flow cytometrypropidium iodide assay and by determining cell proliferation using bromodeoxyuridine incorporation we studied the effect of photodynamic therapy based on the application of 5-aminolevulinic acid on the cells of leukemic cell lines HL60 (human promyelocytic leukemia), HEL (erythroleukemia), DAUDI (B-cell leukemia), JURKAT (T-cell lymphoma), blast cells of patients with acute myelogenous leukemia as well as on normal lymphocytes and normal human bone marrow progenitors."3.70[Selective photodynamic destruction of leukemic cells]. ( Bartosová, J; Cajthamlová, H; Grebenová, D; Hrkal, Z; Klamová, H; Marinov, J, 2000)
"Murine erythroleukemia cells rendered deficient in cAMP-dependent protein kinase (A-kinase) activity by gene transfection are severely impaired in hexamethylene bisacetamide (HMBA)-induced differentiation (Pilz, R."1.29Impaired erythroid-specific gene expression in cAMP-dependent protein kinase-deficient murine erythroleukemia cells. ( Pilz, RB, 1993)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's1 (14.29)18.2507
2000's3 (42.86)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhang, SJ1
Zhang, ZX1
Pilz, RB1
Hrkal, Z1
Cajthamlová, H1
Grebenová, D1
Bartosová, J1
Klamová, H1
Marinov, J1
Chen, JY1
Mak, NQ1
Cheung, NH1
Leung, RN1
Peng, Q1
Malik, Z1
Halbrecht, I1
Djaldetti, M1
Taketani, S1
Kohno, H1
Kinoshita, S1
Tokunaga, R1
Goldenberg, GJ1

Other Studies

7 other studies available for aminolevulinic acid and Experimental Leukemia

ArticleYear
5-aminolevulinic acid-based photodynamic therapy in leukemia cell HL60.
    Photochemistry and photobiology, 2004, Volume: 79, Issue:6

    Topics: Aminolevulinic Acid; Annexins; Cell Death; Cell Survival; Dose-Response Relationship, Drug; Flow Cyt

2004
Impaired erythroid-specific gene expression in cAMP-dependent protein kinase-deficient murine erythroleukemia cells.
    The Journal of biological chemistry, 1993, Sep-25, Volume: 268, Issue:27

    Topics: 5-Aminolevulinate Synthetase; Acetamides; Aminolevulinic Acid; Animals; Blotting, Northern; Cell Dif

1993
[Selective photodynamic destruction of leukemic cells].
    Casopis lekaru ceskych, 2000, Mar-15, Volume: 139, Issue:5

    Topics: Aminolevulinic Acid; Animals; Bone Marrow Purging; Bone Marrow Transplantation; Humans; Leukemia, Ex

2000
Endogenous production of protoporphyrin IX induced by 5-aminolevulinic acid in leukemia cells.
    Acta pharmacologica Sinica, 2001, Volume: 22, Issue:2

    Topics: Aminolevulinic Acid; Animals; Leukemia, Experimental; Leukemia, Myeloid; Mice; Photosensitizing Agen

2001
Regulation of hemoglobin synthesis, iron metabolism, and maturation of Friend leukemic cells by 5-amino levulinic acid and hemin.
    Differentiation; research in biological diversity, 1979, Volume: 13, Issue:2

    Topics: Aminolevulinic Acid; Animals; Cell Differentiation; Culture Media; Heme; Hemin; Hemoglobins; Iron; L

1979
The effects of lead on differentiation of the Friend leukemia cells and rat bone marrow cells.
    Toxicology and applied pharmacology, 1985, Mar-15, Volume: 77, Issue:3

    Topics: Aminolevulinic Acid; Animals; Bone Marrow; Cell Differentiation; Cells, Cultured; Coproporphyrins; E

1985
Drug-induced stimulation of nitrogen mustard and choline transport and other systems in L5178Y lymphoblasts in vitro.
    Cancer research, 1974, Volume: 34, Issue:10

    Topics: Amino Acids; Aminoisobutyric Acids; Aminolevulinic Acid; Animals; Atropine; Biological Transport; Ce

1974