Page last updated: 2024-10-16

aminolevulinic acid and Disease Exacerbation

aminolevulinic acid has been researched along with Disease Exacerbation in 34 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Research Excerpts

ExcerptRelevanceReference
"Introducing 5-aminolevulinic acid-photodynamic diagnosis into transurethral resection reduces residual bladder cancer and improves the cumulative intravesical recurrence-free survival in patients with non-muscle-invasive bladder cancer, indicating its possible therapeutic benefits."8.12Photodynamic diagnosis-assisted transurethral resection using oral 5-aminolevulinic acid decreases residual cancer and improves recurrence-free survival in patients with non-muscle-invasive bladder cancer. ( Harada, S; Honda, T; Kani, N; Kato, T; Matsuoka, Y; Okazoe, H; Sugimoto, M; Taoka, R; Tohi, Y; Tsunemori, H; Ueda, N; Yamasaki, M, 2022)
" Mild or moderate adverse effects were similar for both groups."6.87Effectiveness and safety of 0·5% colchicine cream vs. photodynamic therapy with methyl aminolaevulinate in the treatment of actinic keratosis and skin field cancerization of the forearms: a randomized controlled trial. ( Abbade, LPF; Ferreira, ER; Lima, TRR; Miola, AC; Miot, HA; Schmitt, JV, 2018)
"COL 0·5% cream and MAL-PDT are safe and effective for treating SFC."6.87Effectiveness and safety of 0·5% colchicine cream vs. photodynamic therapy with methyl aminolaevulinate in the treatment of actinic keratosis and skin field cancerization of the forearms: a randomized controlled trial. ( Abbade, LPF; Ferreira, ER; Lima, TRR; Miola, AC; Miot, HA; Schmitt, JV, 2018)
"5-aminolevulinic acid is a protoporphyrin IX precursor used for photodynamic diagnosis."5.72Photodynamic diagnosis-assisted transurethral resection using oral 5-aminolevulinic acid decreases residual cancer and improves recurrence-free survival in patients with non-muscle-invasive bladder cancer. ( Harada, S; Honda, T; Kani, N; Kato, T; Matsuoka, Y; Okazoe, H; Sugimoto, M; Taoka, R; Tohi, Y; Tsunemori, H; Ueda, N; Yamasaki, M, 2022)
" No severe adverse effects were reported."5.43Safety and Efficacy of 5-Aminolevulinic Acid for High Grade Glioma in Usual Clinical Practice: A Prospective Cohort Study. ( Arráez, MÁ; Garcia, R; González, JJ; Montané, E; Rimbau, J; Tardáguila, M; Teixidor, P; Vidal, X; Villalba, G, 2016)
"High-grade gliomas are aggressive, incurable tumors characterized by extensive diffuse invasion of the normal brain parenchyma."5.42A pilot cost-effectiveness analysis of treatments in newly diagnosed high-grade gliomas: the example of 5-aminolevulinic Acid compared with white-light surgery. ( Alves, M; Castel-Branco, M; Esteves, S; Stummer, W, 2015)
"Laser therapy appears the best option among nonsurgical approaches for actinic cheilitis, and PDT showed higher efficacy when sequentially combined with 5% imiquimod."5.05Treatments of actinic cheilitis: A systematic review of the literature. ( Cornacchia, L; Lai, M; Longo, C; Pampena, R; Pellacani, G; Peris, K, 2020)
"Introducing 5-aminolevulinic acid-photodynamic diagnosis into transurethral resection reduces residual bladder cancer and improves the cumulative intravesical recurrence-free survival in patients with non-muscle-invasive bladder cancer, indicating its possible therapeutic benefits."4.12Photodynamic diagnosis-assisted transurethral resection using oral 5-aminolevulinic acid decreases residual cancer and improves recurrence-free survival in patients with non-muscle-invasive bladder cancer. ( Harada, S; Honda, T; Kani, N; Kato, T; Matsuoka, Y; Okazoe, H; Sugimoto, M; Taoka, R; Tohi, Y; Tsunemori, H; Ueda, N; Yamasaki, M, 2022)
" Assessment of the VEGF-secreting activity of resistant colon cancer cells in different degree of malignancy: SW480 and SW620 under hypoxia-like conditions during δ- aminolevulinic acid (ALA) PDT was the objective of our study."3.88Secretion of the angiogenic factor VEGF after photodynamic therapy with ALA under hypoxia-like conditions in colon cancer cells. ( Czuba, ZP; Kawczyk-Krupka, A; Krammer, B; Kwiatek, B; Latos, W; Mertas, A; Sieroń, A; Verwanger, T, 2018)
"Week 52 lesion recurrence rates were 7."2.94A Randomized Trial of Broad Area ALA-PDT for Field Cancerization Mitigation in High-Risk Patients. ( Berg, JE; Ferdon, MB; Houlihan, A; Marcus, SL; Piacquadio, D, 2020)
" Mild or moderate adverse effects were similar for both groups."2.87Effectiveness and safety of 0·5% colchicine cream vs. photodynamic therapy with methyl aminolaevulinate in the treatment of actinic keratosis and skin field cancerization of the forearms: a randomized controlled trial. ( Abbade, LPF; Ferreira, ER; Lima, TRR; Miola, AC; Miot, HA; Schmitt, JV, 2018)
"COL 0·5% cream and MAL-PDT are safe and effective for treating SFC."2.87Effectiveness and safety of 0·5% colchicine cream vs. photodynamic therapy with methyl aminolaevulinate in the treatment of actinic keratosis and skin field cancerization of the forearms: a randomized controlled trial. ( Abbade, LPF; Ferreira, ER; Lima, TRR; Miola, AC; Miot, HA; Schmitt, JV, 2018)
"Non-muscle-invasive bladder cancer (NMIBC) is associated with a high recurrence risk, partly because of the persistence of lesions following transurethral resection of bladder tumour (TURBT) due to the presence of multiple lesions and the difficulty in identifying the exact extent and location of tumours using standard white-light cystoscopy (WLC)."2.50Clinical and cost effectiveness of hexaminolevulinate-guided blue-light cystoscopy: evidence review and updated expert recommendations. ( Babjuk, M; Gontero, P; Jacqmin, D; Karl, A; Kruck, S; Mariappan, P; Palou Redorta, J; Stenzl, A; van Velthoven, R; Witjes, JA; Zaak, D, 2014)
"5-aminolevulinic acid is a protoporphyrin IX precursor used for photodynamic diagnosis."1.72Photodynamic diagnosis-assisted transurethral resection using oral 5-aminolevulinic acid decreases residual cancer and improves recurrence-free survival in patients with non-muscle-invasive bladder cancer. ( Harada, S; Honda, T; Kani, N; Kato, T; Matsuoka, Y; Okazoe, H; Sugimoto, M; Taoka, R; Tohi, Y; Tsunemori, H; Ueda, N; Yamasaki, M, 2022)
"The challenge in the treatment of glioblastoma is the failure to identify the cancer invasive area outside the contrast-enhancing tumour which leads to the high local progression rate."1.56A Neural Network Approach to Identify the Peritumoral Invasive Areas in Glioblastoma Patients by Using MR Radiomics. ( Boonzaier, NR; Li, C; Matys, T; Price, SJ; van der Hoorn, A; Yan, JL, 2020)
"Currently, efficient regimens to reverse atherosclerotic plaques are not available in the clinic."1.51Rapid inhibition of atherosclerotic plaque progression by sonodynamic therapy. ( Cao, W; Cao, Z; Chen, X; Cheng, J; Gao, W; Guo, S; Jiang, Y; Li, B; Li, M; Li, Q; Li, X; Li, Z; Peng, C; Shen, J; Sun, J; Sun, X; Tian, F; Tian, Y; Tian, Z; Wang, H; Wang, P; Wang, T; Wang, W; Wang, Y; Yang, J; Yang, Y; Yao, J; Zhang, Z; Zhao, X; Zhou, Q, 2019)
"The shrunken atherosclerotic plaques displayed compositional alterations, with a reduction in lesional macrophages and lipids."1.51Rapid inhibition of atherosclerotic plaque progression by sonodynamic therapy. ( Cao, W; Cao, Z; Chen, X; Cheng, J; Gao, W; Guo, S; Jiang, Y; Li, B; Li, M; Li, Q; Li, X; Li, Z; Peng, C; Shen, J; Sun, J; Sun, X; Tian, F; Tian, Y; Tian, Z; Wang, H; Wang, P; Wang, T; Wang, W; Wang, Y; Yang, J; Yang, Y; Yao, J; Zhang, Z; Zhao, X; Zhou, Q, 2019)
"Human colorectal cancer cells of different malignant potential SW480 and SW620 were used in the experiment."1.46The effect of ALA-PDT under normoxia and cobalt chloride (CoCl ( Czuba, ZP; Kawczyk-Krupka, A; Krupka, M; Kwiatek, B; Kwiatek, S; Sieroń, K, 2017)
" No severe adverse effects were reported."1.43Safety and Efficacy of 5-Aminolevulinic Acid for High Grade Glioma in Usual Clinical Practice: A Prospective Cohort Study. ( Arráez, MÁ; Garcia, R; González, JJ; Montané, E; Rimbau, J; Tardáguila, M; Teixidor, P; Vidal, X; Villalba, G, 2016)
"High-grade gliomas are aggressive, incurable tumors characterized by extensive diffuse invasion of the normal brain parenchyma."1.42A pilot cost-effectiveness analysis of treatments in newly diagnosed high-grade gliomas: the example of 5-aminolevulinic Acid compared with white-light surgery. ( Alves, M; Castel-Branco, M; Esteves, S; Stummer, W, 2015)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (11.76)29.6817
2010's23 (67.65)24.3611
2020's7 (20.59)2.80

Authors

AuthorsStudies
Taoka, R1
Matsuoka, Y1
Yamasaki, M1
Kani, N1
Honda, T1
Harada, S1
Tohi, Y1
Kato, T1
Okazoe, H1
Tsunemori, H1
Ueda, N1
Sugimoto, M1
Lai, M1
Pampena, R1
Cornacchia, L1
Pellacani, G1
Peris, K1
Longo, C1
Pohar, KS1
Piacquadio, D1
Houlihan, A1
Ferdon, MB1
Berg, JE1
Marcus, SL1
Yan, JL1
Li, C1
van der Hoorn, A1
Boonzaier, NR1
Matys, T1
Price, SJ1
Cerovac, A1
Brigic, A1
Softic, D1
Barakovic, A1
Adzajlic, S1
Lotan, Y1
Chaplin, I1
Ahmadi, H1
Meng, X1
Roberts, S1
Ladi-Seyedian, S1
Bagrodia, A1
Margulis, V1
Woldu, S1
Daneshmand, S1
Kawczyk-Krupka, A2
Czuba, ZP2
Kwiatek, B2
Kwiatek, S1
Krupka, M1
Sieroń, K1
Jacqmin, D2
Jichlinski, P1
Molinier, L1
de la Taille, A1
Irani, J1
Malavaud, B1
Mertas, A1
Latos, W1
Verwanger, T1
Krammer, B1
Sieroń, A1
Kohoutova, D1
Haidry, R2
Banks, M1
Butt, MA1
Dunn, J1
Thorpe, S2
Lovat, L1
Miola, AC1
Ferreira, ER1
Lima, TRR1
Schmitt, JV1
Abbade, LPF1
Miot, HA1
Sun, X1
Guo, S1
Yao, J1
Wang, H1
Peng, C1
Li, B1
Wang, Y1
Jiang, Y1
Wang, T1
Yang, Y1
Cheng, J1
Wang, W1
Cao, Z1
Zhao, X1
Li, X1
Sun, J1
Yang, J1
Tian, F1
Chen, X1
Li, Q1
Gao, W1
Shen, J1
Zhou, Q1
Wang, P1
Li, Z1
Tian, Z1
Zhang, Z1
Cao, W1
Li, M1
Tian, Y1
Jia, QN1
Nguyen, GH1
Fang, K1
Jin, HZ1
Zeng, YP1
Reinhold, U1
Petering, H1
Dirschka, T1
Rozsondai, A1
Gille, J1
Kurzen, H1
Ostendorf, R1
Ebeling, A1
Stocker, M1
Radny, P1
Lee, PK1
Kloser, A1
Liang, WM1
Theng, TS1
Lim, KS1
Tan, WP1
Witjes, JA1
Babjuk, M1
Gontero, P1
Karl, A1
Kruck, S1
Mariappan, P1
Palou Redorta, J1
Stenzl, A1
van Velthoven, R1
Zaak, D2
Kamp, MA2
Felsberg, J1
Sadat, H1
Kuzibaev, J1
Steiger, HJ2
Rapp, M2
Reifenberger, G1
Dibué, M1
Sabel, M2
Esteves, S1
Alves, M1
Castel-Branco, M1
Stummer, W1
Rose, JB1
Armstrong, S1
Hermann, GG1
Kjellberg, J1
Malmström, PU2
Teixidor, P1
Arráez, MÁ1
Villalba, G1
Garcia, R1
Tardáguila, M1
González, JJ1
Rimbau, J1
Vidal, X1
Montané, E1
Dansk, V1
Bläckberg, M1
Malmenäs, M1
Fischer, I1
Bühner, J1
Turowski, B1
Cornelius, JF1
Slotty, PJ1
Toda, M1
Karen, JK1
Hale, EK1
Yeon, JH1
Jung, JY1
Choi, JW1
Kim, BJ1
Lee, JH1
Youn, SW1
Park, KC1
Huh, CH1
Geavlete, B1
Multescu, R1
Georgescu, D1
Jecu, M1
Stanescu, F1
Geavlete, P1
Surong, Z1
Chuanyu, L1
Shizheng, X1
Alloo, A1
Garibyan, L1
LeBoeuf, N1
Lin, G1
Werchniak, A1
Hodi, FS1
Flaherty, KT1
Lawrence, DP1
Lin, JY1
Dunn, JM1
Mackenzie, GD1
Banks, MR1
Mosse, CA1
Green, S1
Rodriguez-Justo, M1
Winstanley, A1
Novelli, MR1
Bown, SG1
Lovat, LB1
Jain, S1
Kockelbergh, RC1
Burger, M1
Stief, CG1
Filbeck, T1
Wieland, WF1
Roessler, W1
Denzinger, S1
Eljamel, MS1
Goodman, C1
Moseley, H1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas[NCT05850377]90 participants (Anticipated)Observational2023-06-01Not yet recruiting
A Single Center Phase II Trial of Vemurafenib (R05185426) in Poor Performance Status Patients With Unresectable Locally Advanced or Metastatic Melanoma Harboring a V600E/K Mutation[NCT01474551]Phase 22 participants (Actual)Interventional2011-11-30Terminated (stopped due to Lack of accrual)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Overall Objective Response

The Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 will be used to determine treatment response. In order to be considered evaluable for response, a patient must have completed at least 1 cycle of therapy. Patients who do not complete a cycle of therapy can be replaced. (NCT01474551)
Timeframe: 2 years

Interventionparticipants (Number)
Stable DiseaseComplete ResponsePartial ResponseProgression of Disease
Vemurafenib1000

Reviews

5 reviews available for aminolevulinic acid and Disease Exacerbation

ArticleYear
Treatments of actinic cheilitis: A systematic review of the literature.
    Journal of the American Academy of Dermatology, 2020, Volume: 83, Issue:3

    Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Cheilitis; Combined Modality Therapy; Dermabrasion; D

2020
Blue Light Cystoscopy: Indications and Outcomes.
    Current urology reports, 2020, Apr-04, Volume: 21, Issue:5

    Topics: Administration, Intravesical; Aminolevulinic Acid; Cystoscopy; Disease Progression; Humans; Light; N

2020
Current methods for photodynamic therapy in the US: comparison of MAL/PDT and ALA/PDT.
    Journal of drugs in dermatology : JDD, 2013, Volume: 12, Issue:8

    Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Disease Progression; Humans; Keratosis, Actinic; Phot

2013
Clinical and cost effectiveness of hexaminolevulinate-guided blue-light cystoscopy: evidence review and updated expert recommendations.
    European urology, 2014, Volume: 66, Issue:5

    Topics: Aminolevulinic Acid; Cost-Benefit Analysis; Cystectomy; Cystoscopy; Disease Progression; Disease-Fre

2014
The role of photodynamic diagnosis in the contemporary management of superficial bladder cancer.
    BJU international, 2005, Volume: 96, Issue:1

    Topics: Aminolevulinic Acid; Anthracenes; Antineoplastic Agents; Carcinoma, Transitional Cell; Cystoscopy; D

2005

Trials

8 trials available for aminolevulinic acid and Disease Exacerbation

ArticleYear
A Randomized Trial of Broad Area ALA-PDT for Field Cancerization Mitigation in High-Risk Patients.
    Journal of drugs in dermatology : JDD, 2020, May-01, Volume: 19, Issue:5

    Topics: Aged; Aminolevulinic Acid; Combined Modality Therapy; Cryotherapy; Disease Progression; Female; Huma

2020
Long-term outcomes of the randomized controlled trial comparing 5-aminolaevulinic acid and Photofrin photodynamic therapy for Barrett's oesophagus related neoplasia.
    Scandinavian journal of gastroenterology, 2018, Volume: 53, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Catheter Ablation; Dihematoporp

2018
Effectiveness and safety of 0·5% colchicine cream vs. photodynamic therapy with methyl aminolaevulinate in the treatment of actinic keratosis and skin field cancerization of the forearms: a randomized controlled trial.
    The British journal of dermatology, 2018, Volume: 179, Issue:5

    Topics: Aged; Aminolevulinic Acid; Atrophy; Biopsy; Carcinoma, Squamous Cell; Colchicine; Disease Progressio

2018
Treatment changes and long-term recurrence rates after hexaminolevulinate (HAL) fluorescence cystoscopy: does it really make a difference in patients with non-muscle-invasive bladder cancer (NMIBC)?
    BJU international, 2012, Volume: 109, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Contrast Media; Cystoscopy; Disease Progression

2012
Photodynamic therapy for multiple eruptive keratoacanthomas associated with vemurafenib treatment for metastatic melanoma.
    Archives of dermatology, 2012, Volume: 148, Issue:3

    Topics: Aged; Aminolevulinic Acid; Antineoplastic Agents; Carcinoma, Squamous Cell; Disease Progression; Dru

2012
A randomised controlled trial of ALA vs. Photofrin photodynamic therapy for high-grade dysplasia arising in Barrett's oesophagus.
    Lasers in medical science, 2013, Volume: 28, Issue:3

    Topics: Adenocarcinoma; Aged; Aminolevulinic Acid; Barrett Esophagus; Dihematoporphyrin Ether; Disease Progr

2013
Photodynamic diagnostics and noninvasive bladder cancer: is it cost-effective in long-term application? A Germany-based cost analysis.
    European urology, 2007, Volume: 52, Issue:1

    Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cost-Benefit Anal

2007
ALA and Photofrin fluorescence-guided resection and repetitive PDT in glioblastoma multiforme: a single centre Phase III randomised controlled trial.
    Lasers in medical science, 2008, Volume: 23, Issue:4

    Topics: Aminolevulinic Acid; Dihematoporphyrin Ether; Disease Progression; Female; Glioblastoma; Humans; Kar

2008

Other Studies

21 other studies available for aminolevulinic acid and Disease Exacerbation

ArticleYear
Photodynamic diagnosis-assisted transurethral resection using oral 5-aminolevulinic acid decreases residual cancer and improves recurrence-free survival in patients with non-muscle-invasive bladder cancer.
    Photodiagnosis and photodynamic therapy, 2022, Volume: 38

    Topics: Aminolevulinic Acid; Disease Progression; Humans; Neoplasm Recurrence, Local; Neoplasm, Residual; Ph

2022
A Neural Network Approach to Identify the Peritumoral Invasive Areas in Glioblastoma Patients by Using MR Radiomics.
    Scientific reports, 2020, 06-16, Volume: 10, Issue:1

    Topics: Adult; Aged; Aminolevulinic Acid; Brain Neoplasms; Cohort Studies; Contrast Media; Diffusion Magneti

2020
Uncontrolled Acute Intermittent Porphyria as a Cause of Spontaneous Abortion.
    Medical archives (Sarajevo, Bosnia and Herzegovina), 2020, Volume: 74, Issue:2

    Topics: Abortion, Spontaneous; Adult; Aminolevulinic Acid; Contraceptives, Oral, Hormonal; Disease Progressi

2020
Prospective evaluation of blue-light flexible cystoscopy with hexaminolevulinate in non-muscle-invasive bladder cancer.
    BJU international, 2021, Volume: 127, Issue:1

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Color; Cystoscopy; Disease Progression; Female

2021
The effect of ALA-PDT under normoxia and cobalt chloride (CoCl
    Photodiagnosis and photodynamic therapy, 2017, Volume: 19

    Topics: Aminolevulinic Acid; Apoptosis; Cell Adhesion Molecules; Cell Count; Cell Line, Tumor; Cell Survival

2017
Observational Studies Requested by European Health Authorities: Governmental Interference or an Enhancement of Everyday Urological Practice? The Hexvix® Observational Patients Evaluation Study as an Example of What to Expect.
    Urologia internationalis, 2017, Volume: 99, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Cystectomy; Cystoscopy; Disease Progression; Di

2017
Secretion of the angiogenic factor VEGF after photodynamic therapy with ALA under hypoxia-like conditions in colon cancer cells.
    Photodiagnosis and photodynamic therapy, 2018, Volume: 21

    Topics: Aminolevulinic Acid; Apoptosis; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Disease Progress

2018
Rapid inhibition of atherosclerotic plaque progression by sonodynamic therapy.
    Cardiovascular research, 2019, 01-01, Volume: 115, Issue:1

    Topics: Aminolevulinic Acid; Animals; Aortic Diseases; Apoptosis; Atorvastatin; Carotid Artery Diseases; Cel

2019
Development of squamous cell carcinoma from erythroplasia of Queyrat following photodynamic therapy.
    European journal of dermatology : EJD, 2018, Jun-01, Volume: 28, Issue:3

    Topics: Aged; Aminolevulinic Acid; Carcinoma, Squamous Cell; Disease Progression; Erythroplasia; Humans; Mal

2018
Photodynamic therapy with a 5-ALA patch does not increase the risk of conversion of actinic keratoses into squamous cell carcinoma: Results of a multicentre non-interventional study.
    Experimental dermatology, 2018, Volume: 27, Issue:12

    Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Disease Progression; DNA Damage; Humans; Keratosis, A

2018
Rapid development of squamous cell carcinoma after photodynamic therapy.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2014, Volume: 40, Issue:5

    Topics: Aged; Aminolevulinic Acid; Bowen's Disease; Carcinoma, Squamous Cell; Disease Progression; Facial Ne

2014
5-ALA-induced fluorescence behavior of reactive tissue changes following glioblastoma treatment with radiation and chemotherapy.
    Acta neurochirurgica, 2015, Volume: 157, Issue:2

    Topics: Aged; Aminolevulinic Acid; Brain Neoplasms; Disease Progression; Female; Fluorescence; Glioblastoma;

2015
A pilot cost-effectiveness analysis of treatments in newly diagnosed high-grade gliomas: the example of 5-aminolevulinic Acid compared with white-light surgery.
    Neurosurgery, 2015, Volume: 76, Issue:5

    Topics: Adult; Aged; Aminolevulinic Acid; Brain Neoplasms; Cost-Benefit Analysis; Disease Progression; Femal

2015
Budget impact of incorporating one instillation of hexaminolevulinate hydrochloride blue-light cytoscopy in transurethral bladder tumour resection for patients with non-muscle-invasive bladder cancer in Sweden.
    BJU international, 2016, Volume: 117, Issue:6B

    Topics: Aminolevulinic Acid; Budgets; Costs and Cost Analysis; Cystoscopy; Disease Progression; Humans; Neop

2016
Safety and Efficacy of 5-Aminolevulinic Acid for High Grade Glioma in Usual Clinical Practice: A Prospective Cohort Study.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Adult; Aged; Aminolevulinic Acid; Brain Neoplasms; Cohort Studies; Disease Progression; Disease-Free

2016
Hexaminolevulinate hydrochloride blue-light flexible cystoscopy in the detection and follow-up of nonmuscle-invasive bladder cancer: cost consequences during outpatient surveillance in Sweden.
    Future oncology (London, England), 2016, Volume: 12, Issue:8

    Topics: Aminolevulinic Acid; Costs and Cost Analysis; Cystectomy; Cystoscopy; Disease Progression; Follow-Up

2016
5-ALA fluorescence of cerebral metastases and its impact for the local-in-brain progression.
    Oncotarget, 2016, Oct-11, Volume: 7, Issue:41

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Brain; Brain Neoplasms; Disease Progression; Fe

2016
Intraoperative navigation and fluorescence imagings in malignant glioma surgery.
    The Keio journal of medicine, 2008, Volume: 57, Issue:3

    Topics: Aminolevulinic Acid; Brain; Brain Neoplasms; Disease Progression; Equipment Design; Fluorescent Dyes

2008
Rapid progression of a basal cell carcinoma after photodynamic therapy.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2010, Volume: 36, Issue:8

    Topics: Aminolevulinic Acid; Biopsy; Carcinoma, Basal Cell; Disease Progression; Humans; Keratosis, Actinic;

2010
Keratoacanthoma aggravated after photodynamic therapy.
    The Journal of dermatology, 2010, Volume: 37, Issue:8

    Topics: Aminolevulinic Acid; Disease Progression; Humans; Keratoacanthoma; Male; Middle Aged; Nose Neoplasms

2010
Experimental study of δ-ALA-PDT in the treatment in BXSB lupus-prone mice.
    Acta dermatovenerologica Croatica : ADC, 2011, Volume: 19, Issue:4

    Topics: Aminolevulinic Acid; Animals; Antibodies, Antinuclear; Disease Progression; Immune Complex Diseases;

2011