aminolevulinic acid has been researched along with Di Guglielmo Disease in 24 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In somatic cell hybrids formed by the fusion of mouse erythroleukemic cells with cultured mouse lymphoma cells, retention of the X chromosome donated by the lymphoma parent is correlated with inhibition of hemoglobin accumulation in response to dimethyl sulfoxide." | 3.66 | X-linked control of globin mRNA and hemoglobin production in erythroleukemia-lymphoma cell hybrids. ( Benoff, S; Bruce, SA; Skoultchi, AI, 1980) |
| "ALA-induced PPIX accumulation in erythroleukemia cells (UT-7 and K562) was impaired by PK 11195, a competitive inhibitor of both transmembrane proteins TSPO (1 and 2)." | 1.56 | TSPO2 translocates 5-aminolevulinic acid into human erythroleukemia cells. ( Gouya, L; Hattab, C; Lacapere, JJ; Lefevre, SD; Manceau, H; Mirmiran, A; Ostuni, MA; Peoc'h, K; Puy, H; Schmitt, C; Sugier, HR, 2020) |
| "Murine erythroleukemia cells rendered deficient in cAMP-dependent protein kinase (A-kinase) activity by gene transfection are severely impaired in hexamethylene bisacetamide (HMBA)-induced differentiation (Pilz, R." | 1.29 | Impaired erythroid-specific gene expression in cAMP-dependent protein kinase-deficient murine erythroleukemia cells. ( Pilz, RB, 1993) |
| "Thymidine incorporation was inhibited by the photodynamic effect depending on porphyrin concentration." | 1.28 | Inactivation of erythrocytic, lymphocytic and myelocytic leukemic cells by photoexcitation of endogenous porphyrins. ( Ehrenberg, B; Faraggi, A; Malik, Z, 1989) |
| "The properties of erythroleukemia x lymphoma cell hybrids are compared with those of a series of erythroleukemia x bone marrow cell hybrids." | 1.26 | X-linked control of globin mRNA and hemoglobin production in erythroleukemia-lymphoma cell hybrids. ( Benoff, S; Bruce, SA; Skoultchi, AI, 1980) |
| "Dimethyl sulfoxide-treated hybrid cells accumulate polyribosomal globin mRNA to levels comparable to those of the parental erythroleukemic cells under the same conditions." | 1.26 | Negative control of hemoglobin production in somatic cell hybrids due to heme deficiency. ( Benoff, S; Bruce, SA; Skoultchi, AI, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (45.83) | 18.7374 |
| 1990's | 6 (25.00) | 18.2507 |
| 2000's | 4 (16.67) | 29.6817 |
| 2010's | 2 (8.33) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Feuerstein, T | 2 |
| Schauder, A | 2 |
| Malik, Z | 8 |
| Berkovitch-Luria, G | 1 |
| Yakobovitch, S | 1 |
| Weitman, M | 1 |
| Nudelman, A | 1 |
| Rozic, G | 1 |
| Rephaeli, A | 1 |
| Benoff, S | 2 |
| Bruce, SA | 2 |
| Skoultchi, AI | 2 |
| Pilz, RB | 1 |
| Hoang, T | 1 |
| Paradis, E | 1 |
| Brady, G | 1 |
| Billia, F | 1 |
| Nakahara, K | 1 |
| Iscove, NN | 1 |
| Kirsch, IR | 1 |
| Picard, V | 1 |
| Renaudie, F | 1 |
| Porcher, C | 1 |
| Hentze, MW | 1 |
| Grandchamp, B | 1 |
| Beaumont, C | 1 |
| Kawasaki, N | 1 |
| Morimoto, K | 1 |
| Tanimoto, T | 1 |
| Hayakawa, T | 1 |
| Rafferty, SP | 1 |
| Domachowske, JB | 1 |
| Malech, HL | 1 |
| Yücesoy, B | 1 |
| Turhan, A | 1 |
| Mirshahidi, S | 1 |
| Ure, M | 1 |
| Imir, T | 1 |
| Karakaya, A | 1 |
| Belicková, M | 1 |
| Bruchová, H | 1 |
| Cajthamlová, H | 1 |
| Hrkal, Z | 1 |
| Brdicka, R | 1 |
| Taketani, S | 2 |
| Furukawa, T | 1 |
| Furuyama, K | 1 |
| Woodard, SI | 1 |
| Dailey, HA | 1 |
| Djaldetti, M | 2 |
| Halbrecht, I | 1 |
| Ehrenberg, B | 1 |
| Faraggi, A | 1 |
| Hradilek, A | 1 |
| Neuwirt, J | 1 |
| Stoeckert, CJ | 1 |
| Nicolaides, NC | 1 |
| Haines, KM | 1 |
| Lugaci, H | 2 |
| Hanania, J | 1 |
| Laskey, JD | 1 |
| Ponka, P | 1 |
| Schulman, HM | 1 |
| Kohno, H | 1 |
| Kinoshita, S | 1 |
| Tokunaga, R | 1 |
| Manceau, H | 1 |
| Lefevre, SD | 1 |
| Mirmiran, A | 1 |
| Hattab, C | 1 |
| Sugier, HR | 1 |
| Schmitt, C | 1 |
| Peoc'h, K | 1 |
| Puy, H | 1 |
| Ostuni, MA | 1 |
| Gouya, L | 1 |
| Lacapere, JJ | 1 |
24 other studies available for aminolevulinic acid and Di Guglielmo Disease
| Article | Year |
|---|---|
Silencing of ALA dehydratase affects ALA-photodynamic therapy efficacy in K562 erythroleukemic cells.
Topics: Aminolevulinic Acid; Cell Death; Gene Silencing; Humans; K562 Cells; Leukemia, Erythroblastic, Acute | 2009 |
The centrality of PBGD expression levels on ALA-PDT efficacy.
Topics: Aminolevulinic Acid; Apoptosis; Gene Expression Regulation, Neoplastic; Humans; Hydroxymethylbilane | 2011 |
A multifunctional 5-aminolevulinic acid derivative induces erythroid differentiation of K562 human erythroleukemic cells.
Topics: alpha-Globins; Aminolevulinic Acid; Butyric Acid; Cell Differentiation; Cell Proliferation; Erythroi | 2012 |
X-linked control of globin mRNA and hemoglobin production in erythroleukemia-lymphoma cell hybrids.
Topics: Aminolevulinic Acid; Animals; Dimethyl Sulfoxide; Female; Genetic Linkage; Globins; Hemin; Hemoglobi | 1980 |
Impaired erythroid-specific gene expression in cAMP-dependent protein kinase-deficient murine erythroleukemia cells.
Topics: 5-Aminolevulinate Synthetase; Acetamides; Aminolevulinic Acid; Animals; Blotting, Northern; Cell Dif | 1993 |
Opposing effects of the basic helix-loop-helix transcription factor SCL on erythroid and monocytic differentiation.
Topics: Adult; Aminolevulinic Acid; Base Sequence; Basic Helix-Loop-Helix Transcription Factors; Cell Differ | 1996 |
Overexpression of the ferritin H subunit in cultured erythroid cells changes the intracellular iron distribution.
Topics: Acetamides; Aminolevulinic Acid; Animals; Base Sequence; Cell Compartmentation; Cell Differentiation | 1996 |
Control of hemoglobin synthesis in erythroid differentiating K562 cells. I. Role of iron in erythroid cell heme synthesis.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Butyrates; Butyric Acid; Cell Differentiation; Ce | 1996 |
Inhibition of hemoglobin expression by heterologous production of nitric oxide synthase in the K562 erythroleukemic cell line.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Base Sequence; Butyrates; Butyric Acid; Gene Expr | 1996 |
Effects of high-level exposure to lead on NK cell activity and T-lymphocyte functions in workers.
Topics: Adult; Aminolevulinic Acid; Cell Division; Humans; Killer Cells, Natural; Lead; Leukemia, Erythrobla | 1997 |
Genes involved in the destruction of leukaemic cells by induced photosensitivity.
Topics: Aminolevulinic Acid; Apoptosis; Cell Survival; DNA, Complementary; Gene Expression Profiling; Gene E | 2000 |
Expression of coproporphyrinogen oxidase and synthesis of hemoglobin in human erythroleukemia K562 cells.
Topics: Aminolevulinic Acid; Animals; Base Sequence; Coproporphyrinogen Oxidase; DNA Primers; Gene Expressio | 2001 |
Multiple regulatory steps in erythroid heme biosynthesis.
Topics: Aminolevulinic Acid; Animals; Enzyme Inhibitors; Erythroid Precursor Cells; Erythropoiesis; Heme; He | 2000 |
Negative control of hemoglobin production in somatic cell hybrids due to heme deficiency.
Topics: Aminolevulinic Acid; Bone Marrow; Cell Line; Dimethyl Sulfoxide; Female; Genetic Linkage; Heme; Hemi | 1978 |
5-Aminolevulinic acid stimulation of porphyrin and hemoglobin synthesis by uninduced Friend erythroleukemic cells.
Topics: Aminolevulinic Acid; Animals; Cell Line; Hemoglobins; Iron; Kinetics; Leukemia, Erythroblastic, Acut | 1979 |
Regulation of hemoglobin synthesis, iron metabolism, and maturation of Friend leukemic cells by 5-amino levulinic acid and hemin.
Topics: Aminolevulinic Acid; Animals; Cell Differentiation; Culture Media; Heme; Hemin; Hemoglobins; Iron; L | 1979 |
Inactivation of erythrocytic, lymphocytic and myelocytic leukemic cells by photoexcitation of endogenous porphyrins.
Topics: Aminolevulinic Acid; Animals; Cell Survival; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leuk | 1989 |
Inhibition of cellular iron uptake by haem in mouse erythroleukaemia cells.
Topics: Acetamides; Aminolevulinic Acid; Animals; Cell Differentiation; Cells, Cultured; Glycine; Heme; Hemi | 1989 |
Cytosine arabinoside plus hemin treatment of a human erythroid cell line, KMOE, strongly induces embryonic, fetal, and adult beta-like globin genes.
Topics: Aminolevulinic Acid; Cytarabine; Dimethyl Sulfoxide; Drug Synergism; Erythroid Precursor Cells; Eryt | 1989 |
Stimulation of Friend erythroleukemic cell cytodifferentiation by 5-amino levulinic acid; porphyrins, cell size, segregation of sialoglycoproteins, and nuclear translocation.
Topics: Aminolevulinic Acid; Animals; Cell Differentiation; Cell Line; Cell Nucleus; Dimethyl Sulfoxide; Flo | 1988 |
Control of heme synthesis during Friend cell differentiation: role of iron and transferrin.
Topics: Aminolevulinic Acid; Animals; Cell Differentiation; Friend murine leukemia virus; Glycine; Heme; Hum | 1986 |
Destruction of erythroleukaemic cells by photoactivation of endogenous porphyrins.
Topics: Aminolevulinic Acid; Animals; Cell Survival; Coproporphyrins; Friend murine leukemia virus; Leukemia | 1987 |
The effects of lead on differentiation of the Friend leukemia cells and rat bone marrow cells.
Topics: Aminolevulinic Acid; Animals; Bone Marrow; Cell Differentiation; Cells, Cultured; Coproporphyrins; E | 1985 |
TSPO2 translocates 5-aminolevulinic acid into human erythroleukemia cells.
Topics: Aminolevulinic Acid; Biological Transport; Cell Membrane; Green Fluorescent Proteins; Humans; Isoqui | 2020 |