aminolevulinic acid has been researched along with Dermatitis, Contact, Phototoxic in 18 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
| Excerpt | Relevance | Reference |
|---|---|---|
| "On 21 patients, skin phototoxicity was determined prior to as well as 4, 8 and 28 h after intravesical instillation of a 3% ALA solution by exposing small skin areas to a progressively graded series of defined UVA-light doses (n = 9; 5-80 J/cm(2))." | 5.31 | No generalized skin phototoxicity after intravesical application of 5-aminolevulinic acid for fluorescence diagnosis of superficial bladder cancer. ( Filbeck, T; Karrer, S; Pichlmeier, U; Rössler, W; Szeimies, RM; Wieland, WF; Wimmershoff, MB, 2000) |
| "To verify if photodynamic therapy (PDT) could overcome multidrug resistance (MDR) when it it applied to eradicate minimal residual disease in patients with leukemia, we investigated the fluorescence kinetics of 5-aminolaevulinic acid (ALA)-induced protoporphyrin IX (PpIX) and the effect of subsequent photodynamic therapy on MDR leukemia cells, which express P-glycoprotein (P-gp), as well as on their parent cells." | 3.71 | 5-Aminolaevulinic acid-mediated photodynamic therapy in multidrug resistant leukemia cells. ( Hashimoto, K; Li, W; Ohnishi, K; Ohno, R; Yamada, I; Zhang, WJ, 2001) |
| "Improvement regarding dysphagia, stenosis diameter, and tumor length could be obtained in both treatment arms with a significant difference in favour of the Photosan-group, P = 0." | 2.70 | Does new photosensitizer improve photodynamic therapy in advanced esophageal carcinoma? ( Maier, A; Matzi, V; Pinter, H; Rehak, P; Smolle-Jüttner, FM; Tomaselli, F, 2001) |
| "On 21 patients, skin phototoxicity was determined prior to as well as 4, 8 and 28 h after intravesical instillation of a 3% ALA solution by exposing small skin areas to a progressively graded series of defined UVA-light doses (n = 9; 5-80 J/cm(2))." | 1.31 | No generalized skin phototoxicity after intravesical application of 5-aminolevulinic acid for fluorescence diagnosis of superficial bladder cancer. ( Filbeck, T; Karrer, S; Pichlmeier, U; Rössler, W; Szeimies, RM; Wieland, WF; Wimmershoff, MB, 2000) |
| "Assessment of phototoxicity of PDT using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay showed that PDT was effective in NB4, NB4/MDR, NOMO-1 and NOMO-1/ADR cells, which accumulated high levels of PpIX, but not effective in K562 and K562/ADR cell lines, which accumulated relatively low levels of PpIX." | 1.31 | 5-Aminolaevulinic acid-mediated photodynamic therapy in multidrug resistant leukemia cells. ( Hashimoto, K; Li, W; Ohnishi, K; Ohno, R; Yamada, I; Zhang, WJ, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 12 (66.67) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Hassoun, LA | 1 |
| Shi, VY | 1 |
| Sivamani, RK | 1 |
| Stevenson, ML | 1 |
| Karen, JK | 1 |
| Hale, EK | 1 |
| Ortner, VK | 1 |
| Haedersdal, M | 1 |
| Wulf, HC | 1 |
| Togsverd-Bo, K | 1 |
| Toll, A | 1 |
| Parera, ME | 1 |
| Vélez, M | 1 |
| Pujol, RM | 1 |
| Neumann, NJ | 1 |
| Hanneken, S | 1 |
| Ruzicka, T | 1 |
| Lehmann, P | 1 |
| McCarron, PA | 1 |
| Donnelly, RF | 1 |
| Gilmore, BF | 1 |
| Woolfson, AD | 1 |
| McClelland, R | 1 |
| Zawislak, A | 1 |
| Price, JH | 1 |
| Angell-Petersen, E | 1 |
| Christensen, C | 1 |
| Müller, CR | 1 |
| Warloe, T | 2 |
| Stepp, H | 1 |
| Waidelich, R | 1 |
| Boiy, A | 1 |
| Roelandts, R | 1 |
| van den Oord, J | 1 |
| de Witte, PA | 1 |
| Redbord, KP | 1 |
| Hanke, CW | 1 |
| Fink-Puches, R | 1 |
| Soyer, HP | 1 |
| Hofer, A | 1 |
| Kerl, H | 1 |
| Wolf, P | 1 |
| Iinuma, S | 1 |
| Schomacker, KT | 1 |
| Wagnieres, G | 1 |
| Rajadhyaksha, M | 1 |
| Bamberg, M | 1 |
| Momma, T | 1 |
| Hasan, T | 1 |
| Liang, H | 1 |
| Do, T | 1 |
| Kasravi, S | 1 |
| Aurasteh, P | 1 |
| Nguyen, A | 1 |
| Huang, A | 1 |
| Wang, Z | 1 |
| Berns, MW | 1 |
| Filbeck, T | 1 |
| Wimmershoff, MB | 1 |
| Pichlmeier, U | 1 |
| Karrer, S | 1 |
| Wieland, WF | 1 |
| Szeimies, RM | 1 |
| Rössler, W | 1 |
| Li, W | 1 |
| Zhang, WJ | 1 |
| Ohnishi, K | 1 |
| Yamada, I | 1 |
| Ohno, R | 1 |
| Hashimoto, K | 1 |
| Maier, A | 1 |
| Tomaselli, F | 1 |
| Matzi, V | 1 |
| Rehak, P | 1 |
| Pinter, H | 1 |
| Smolle-Jüttner, FM | 1 |
| Peng, Q | 1 |
| Moan, J | 1 |
| Nesland, JM | 1 |
| Rimington, C | 1 |
1 review available for aminolevulinic acid and Dermatitis, Contact, Phototoxic
| Article | Year |
|---|---|
[Fluorescence diagnosis and photodynamic therapy in urology].
Topics: Aminolevulinic Acid; Carcinoma in Situ; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II | 2007 |
4 trials available for aminolevulinic acid and Dermatitis, Contact, Phototoxic
| Article | Year |
|---|---|
Phototoxic reaction and porphyrin fluorescence in skin after topical application of methyl aminolaevulinate.
Topics: Administration, Topical; Adult; Aminolevulinic Acid; Dermatitis, Phototoxic; Double-Blind Method; Fe | 2007 |
Topical photodynamic therapy for dermatologic disorders: results and complications.
Topics: Administration, Cutaneous; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Dermatitis, Phototox | 2007 |
Long-term follow-up and histological changes of superficial nonmelanoma skin cancers treated with topical delta-aminolevulinic acid photodynamic therapy.
Topics: Administration, Topical; Aged; Aged, 80 and over; Aminolevulinic Acid; Antineoplastic Agents; Carcin | 1998 |
Does new photosensitizer improve photodynamic therapy in advanced esophageal carcinoma?
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Squamous Cell; Deglutition | 2001 |
13 other studies available for aminolevulinic acid and Dermatitis, Contact, Phototoxic
| Article | Year |
|---|---|
Phototoxicity Secondary to Home Fireplace Exposure After Photodynamic Therapy for Actinic Keratosis.
Topics: Aminolevulinic Acid; Dermatitis, Phototoxic; Humans; Keratosis, Actinic; Photochemotherapy | 2021 |
Laser-Assisted Photodynamic Therapy: Two Novel Protocols for Enhanced Treatment Results.
Topics: Administration, Cutaneous; Aged; Aminolevulinic Acid; Clinical Protocols; Dermatitis, Phototoxic; Fe | 2017 |
Intense phototoxic reactions to photodynamic therapy in immunosuppressed renal transplant patients.
Topics: Aminolevulinic Acid; Dermatitis, Phototoxic; Female; Humans; Immunocompromised Host; Kidney Transpla | 2018 |
Letter: photodynamic therapy with methyl aminolevulinate induces phototoxic reactions on areas of the nose adjacent to basal cell carcinomas and actinic keratoses.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Dermatitis, Phototoxic; Humans; | 2008 |
Drug-induced photosensitivity.
Topics: Aminolevulinic Acid; Amiodarone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Ca | 2009 |
Phototoxicity of exogenous protoporphyrin IX and delta-aminolevulinic acid in the photo hen's egg test.
Topics: Aminolevulinic Acid; Animals; Chick Embryo; Dermatitis, Phototoxic; Disease Models, Animal; Forecast | 2004 |
Phototoxicity of 5-aminolevulinic acid in the HeLa cell line as an indicative measure of photodynamic effect after topical administration to gynecological lesions of intraepithelial form.
Topics: Aminolevulinic Acid; Cell Death; Cell Survival; Dermatitis, Phototoxic; Diffusion Chambers, Culture; | 2004 |
Photosensitizing activity of hypericin and hypericin acetate after topical application on normal mouse skin.
Topics: Administration, Topical; Aminolevulinic Acid; Animals; Anthracenes; Dermatitis, Phototoxic; Female; | 2008 |
In vivo fluence rate and fractionation effects on tumor response and photobleaching: photodynamic therapy with two photosensitizers in an orthotopic rat tumor model.
Topics: Aminolevulinic Acid; Animals; Dermatitis, Phototoxic; Disease Models, Animal; Female; Light; Microsc | 1999 |
Chromosomes are target sites for photodynamic therapy as demonstrated by subcellular laser microirradiation.
Topics: Aminolevulinic Acid; Animals; Cell Line; Chromosomes, Human; Dermatitis, Phototoxic; Fluorescence; H | 2000 |
No generalized skin phototoxicity after intravesical application of 5-aminolevulinic acid for fluorescence diagnosis of superficial bladder cancer.
Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Dermatitis, Photo | 2000 |
5-Aminolaevulinic acid-mediated photodynamic therapy in multidrug resistant leukemia cells.
Topics: Aminolevulinic Acid; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Dermatitis, | 2001 |
Distribution and photosensitizing efficiency of porphyrins induced by application of exogenous 5-aminolevulinic acid in mice bearing mammary carcinoma.
Topics: Aminolevulinic Acid; Animals; Dermatitis, Phototoxic; Female; Mammary Neoplasms, Experimental; Mice; | 1992 |