aminolevulinic acid has been researched along with Chronic Disease in 29 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Hexachlorobenzene porphyria in the rat provides a suitable experimental model of the stages of development of human chronic hepatic porphyria." | 7.65 | Hexachlorobenzene porphyria in rats as a model for human chronic hepatic porphyrias. ( Doss, M; Koss, G; Schermuly, E, 1976) |
| "The dynamics of conjugation of 14C-bilirubin injected intravenously during cholestasis is known from studies in rats and dogs." | 7.65 | Conjugation of non-erythroid bilirubin in chronic experimental cholestasis in the dog. ( Bergan, A; Gjelstad, N; Ostrem, T, 1975) |
| "Porphyrias are a group of eight rare inherited metabolic disorders of heme biosynthesis pathway." | 4.86 | Porphyrias at a glance: diagnosis and treatment. ( Brancaleoni, V; Cappellini, MD; Di Pierro, E; Graziadei, G; Tavazzi, D, 2010) |
| "Disturbances in the biosynthesis of porphyrins in erythrocytes were investigated in 50 patients with chronic nephritis after incubation with delta-aminolevulinic acid." | 3.66 | [Chronic nephritis--porphyrin biosynthesis and nephrogenic anemia]. ( Iwanov, E; Pisanets, M, 1983) |
| " Hexachlorobenzene porphyria in the rat provides a suitable experimental model of the stages of development of human chronic hepatic porphyria." | 3.65 | Hexachlorobenzene porphyria in rats as a model for human chronic hepatic porphyrias. ( Doss, M; Koss, G; Schermuly, E, 1976) |
| "The dynamics of conjugation of 14C-bilirubin injected intravenously during cholestasis is known from studies in rats and dogs." | 3.65 | Conjugation of non-erythroid bilirubin in chronic experimental cholestasis in the dog. ( Bergan, A; Gjelstad, N; Ostrem, T, 1975) |
| "Porphyrias are a group of eight rare inherited metabolic disorders of heme biosynthesis pathway." | 2.46 | Porphyrias at a glance: diagnosis and treatment. ( Brancaleoni, V; Cappellini, MD; Di Pierro, E; Graziadei, G; Tavazzi, D, 2010) |
| "Acne vulgaris is a common dermatological disorder." | 1.37 | Successful treatment of refractory facial acne using repeat short-cycle ALA-PDT: Case study. ( Ding, HL; Huang, Z; Wang, HW; Wang, XL, 2011) |
| "Cutaneous verrucous carcinoma is a low-grade and well-differentiated variant of squamous cell carcinoma." | 1.34 | Photodynamic therapy for cutaneous verrucous carcinoma. ( Nikkels, AF; Piérard, GE; Quatresooz, P; Thirion, L, 2007) |
| " The folliculitis had occurred in areas of acne-prone skin of the patients, mainly after long-term administration of antibiotics." | 1.34 | Topical methyl aminolevulinate photodynamic therapy for the treatment of folliculitis. ( Horn, M; Wolf, P, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (27.59) | 18.7374 |
| 1990's | 5 (17.24) | 18.2507 |
| 2000's | 10 (34.48) | 29.6817 |
| 2010's | 6 (20.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rakesh, N | 1 |
| Clint, JB | 1 |
| Reddy, SS | 1 |
| Nagi, R | 1 |
| Chauhan, P | 1 |
| Sharma, S | 1 |
| Sharma, P | 1 |
| Kaur, A | 1 |
| Shetty, B | 1 |
| Ashwini, S | 1 |
| Pavan Kumar, T | 1 |
| Vidya, GS | 1 |
| Liu, Y | 1 |
| Ma, Y | 1 |
| Xiang, LH | 1 |
| Patel, D | 1 |
| Alhawaj, R | 1 |
| Wolin, MS | 1 |
| Lei, X | 1 |
| Liu, B | 1 |
| Huang, Z | 2 |
| Wu, J | 1 |
| Sotiriou, E | 1 |
| Apalla, Z | 1 |
| Maliamani, F | 1 |
| Ioannides, D | 1 |
| Cappellini, MD | 1 |
| Brancaleoni, V | 1 |
| Graziadei, G | 1 |
| Tavazzi, D | 1 |
| Di Pierro, E | 1 |
| Ding, HL | 1 |
| Wang, XL | 1 |
| Wang, HW | 1 |
| Escudero, A | 1 |
| Nagore, E | 1 |
| Sevila, A | 1 |
| Sanmartin, O | 1 |
| Botella, R | 1 |
| Guillen, C | 1 |
| Endlicher, E | 1 |
| Rümmele, P | 1 |
| Hausmann, F | 1 |
| Rath, HC | 1 |
| Knüchel, R | 1 |
| Krieg, RC | 1 |
| Schölmerich, J | 2 |
| Messmann, H | 2 |
| Radakovic-Fijan, S | 2 |
| Blecha-Thalhammer, U | 1 |
| Schleyer, V | 2 |
| Szeimies, RM | 2 |
| Zwingers, T | 2 |
| Hönigsmann, H | 1 |
| Tanew, A | 2 |
| Yim, YC | 1 |
| Lee, ES | 1 |
| Chung, PS | 1 |
| Rhee, CK | 1 |
| Karrer, S | 1 |
| Landthaler, M | 1 |
| Clayton, TH | 1 |
| Harrison, PV | 1 |
| Nikkels, AF | 1 |
| Thirion, L | 1 |
| Quatresooz, P | 1 |
| Piérard, GE | 1 |
| Horn, M | 1 |
| Wolf, P | 1 |
| Lopez-Navarro, N | 1 |
| Alcaraz, I | 1 |
| Bosch, RJ | 1 |
| Tejera, A | 1 |
| Herrera, E | 1 |
| Iwanov, E | 1 |
| Pisanets, M | 1 |
| Sada-Cieślar, M | 1 |
| Mazur, B | 1 |
| Buszman, Z | 1 |
| Cieślar, G | 1 |
| Boehncke, WH | 1 |
| Sterry, W | 1 |
| Kaufmann, R | 1 |
| Soldatovic, D | 1 |
| Vujanovic, D | 1 |
| Matovic, V | 1 |
| Plamenac, Z | 1 |
| Collins, P | 1 |
| Robinson, DJ | 1 |
| Stringer, MR | 1 |
| Stables, GI | 1 |
| Sheehan-Dare, RA | 1 |
| Kullmann, F | 1 |
| Wild, T | 1 |
| Knüchel-Clarke, R | 1 |
| Rüschoff, J | 1 |
| Gross, V | 1 |
| Holstege, A | 1 |
| Petryka, ZJ | 1 |
| Doss, M | 2 |
| Schermuly, E | 1 |
| Koss, G | 1 |
| Schwanitz, G | 1 |
| Gebhart, E | 1 |
| Rott, HD | 1 |
| Schaller, KH | 1 |
| Essing, HG | 1 |
| Lauer, O | 1 |
| Prestele, H | 1 |
| Bergan, A | 1 |
| Ostrem, T | 1 |
| Gjelstad, N | 1 |
| Dhawan, M | 1 |
| Flora, SJ | 1 |
| Tandon, SK | 1 |
| Bartlett, RS | 1 |
| Rousseau, JE | 1 |
| Frier, HI | 1 |
| Hall, RC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Oral Lichen Planus Photodynamic Treatment[NCT05127083] | 60 participants (Actual) | Interventional | 2018-06-04 | Completed | |||
| Efficacy and Safety of Methylene Blue -Mediated Photodynamic Therapy for Diabetic Lower Limb Ulcer : a Randomized Controlled Study[NCT03222544] | 60 participants (Anticipated) | Interventional | 2019-04-29 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for aminolevulinic acid and Chronic Disease
| Article | Year |
|---|---|
Successful treatment of recalcitrant dissecting cellulitis of the scalp with ALA-PDT: case report and literature review.
Topics: Administration, Topical; Adult; Aminolevulinic Acid; Cellulitis; Chronic Disease; Female; Humans; Ph | 2013 |
Porphyrias at a glance: diagnosis and treatment.
Topics: Acute Disease; Aminolevulinic Acid; Chronic Disease; Genetic Testing; Heme; Humans; Porphobilinogen; | 2010 |
[Pathobiochemistry of porphyrias].
Topics: Acute Disease; Aminolevulinic Acid; Catalase; Chronic Disease; Cytochrome P-450 Enzyme System; Heme; | 1977 |
4 trials available for aminolevulinic acid and Chronic Disease
| Article | Year |
|---|---|
A clinical study of photodynamic therapy for chronic skin ulcers in lower limbs infected with Pseudomonas aeruginosa.
Topics: Adult; Aged; Aminolevulinic Acid; Bacterial Load; China; Chronic Disease; Colony Count, Microbial; F | 2015 |
Topical aminolaevulinic acid-based photodynamic therapy as a treatment option for psoriasis? Results of a randomized, observer-blinded study.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Chronic Disease; Female; Humans; Male; Middle A | 2005 |
Disappointing results and low tolerability of photodynamic therapy with topical 5-aminolaevulinic acid in psoriasis. A randomized, double-blind phase I/II study.
Topics: Administration, Topical; Adult; Aminolevulinic Acid; Chronic Disease; Double-Blind Method; Female; H | 2006 |
The variable response of plaque psoriasis after a single treatment with topical 5-aminolaevulinic acid photodynamic therapy.
Topics: Aminolevulinic Acid; Chronic Disease; Dose-Response Relationship, Radiation; Humans; Photochemothera | 1997 |
22 other studies available for aminolevulinic acid and Chronic Disease
| Article | Year |
|---|---|
Clinical evaluation of photodynamic therapy for the treatment of refractory oral Lichen planus - A case series.
Topics: Adult; Aged; Aminolevulinic Acid; Chronic Disease; Female; Humans; Lichen Planus, Oral; Male; Middle | 2018 |
Exposure of mice to chronic hypoxia attenuates pulmonary arterial contractile responses to acute hypoxia by increases in extracellular hydrogen peroxide.
Topics: Acute Disease; Aminolevulinic Acid; Animals; Antihypertensive Agents; Aorta; Cell Adhesion Molecules | 2014 |
Treatment of recalcitrant hidradenitis suppurativa with photodynamic therapy: report of five cases.
Topics: Adult; Aminolevulinic Acid; Chronic Disease; Female; Hidradenitis Suppurativa; Humans; Male; Photoch | 2009 |
Successful treatment of refractory facial acne using repeat short-cycle ALA-PDT: Case study.
Topics: Acne Vulgaris; Aminolevulinic Acid; Chronic Disease; Facial Dermatoses; Humans; Male; Photochemother | 2011 |
Chronic X-ray dermatitis treated by topical 5-aminolaevulinic acid-photodynamic therapy.
Topics: Aged; Aminolevulinic Acid; Chronic Disease; Dermatitis, Occupational; Hand Dermatoses; Humans; Male; | 2002 |
Detection of dysplastic lesions by fluorescence in a model of chronic colitis in rats after local application of 5-aminolevulinic acid and its esterified derivatives.
Topics: Administration, Topical; Aminolevulinic Acid; Animals; Biopsy; Chronic Disease; Colitis; Colon; Dise | 2004 |
Recalcitrant palmoplantar pustular psoriasis successfully treated with topical 5-aminolaevulinic acid photodynamic therapy.
Topics: Adult; Aminolevulinic Acid; Chronic Disease; Dose-Response Relationship, Radiation; Female; Humans; | 2005 |
Photodynamic therapy for infected leg ulcers.
Topics: Aged; Aminolevulinic Acid; Chronic Disease; Female; Humans; Leg Ulcer; Methicillin Resistance; Photo | 2007 |
Photodynamic therapy for cutaneous verrucous carcinoma.
Topics: Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Verrucous; Chronic Disease; Drug Administration S | 2007 |
Topical methyl aminolevulinate photodynamic therapy for the treatment of folliculitis.
Topics: Administration, Topical; Adult; Aminolevulinic Acid; Chronic Disease; Folliculitis; Humans; Male; Ph | 2007 |
Keratosis lichenoides chronica: response to photodynamic therapy.
Topics: Aminolevulinic Acid; Chronic Disease; Female; Humans; Keratosis; Lichenoid Eruptions; Middle Aged; P | 2008 |
[Chronic nephritis--porphyrin biosynthesis and nephrogenic anemia].
Topics: Adolescent; Adult; Aminolevulinic Acid; Anemia; Chronic Disease; Erythrocytes; Female; Humans; Male; | 1983 |
[Lead poisoning in children from the industrial region of Silesia--markers of chronic intoxication].
Topics: Adolescent; Aminolevulinic Acid; Biomarkers; Case-Control Studies; Child; Chronic Disease; Environme | 1994 |
Treatment of psoriasis by topical photodynamic therapy with polychromatic light.
Topics: Administration, Topical; Aminolevulinic Acid; Anthralin; Chronic Disease; Follow-Up Studies; Humans; | 1994 |
Compared effects of high oral Mg supplements and of EDTA chelating agent on chronic lead intoxication in rabbits.
Topics: Administration, Oral; Aminolevulinic Acid; Analysis of Variance; Animals; Chelating Agents; Chronic | 1997 |
Detection of dysplastic lesions by fluorescence in a model of colitis in rats after previous photosensitization with 5-aminolaevulinic acid.
Topics: Acute Disease; Aminolevulinic Acid; Animals; Chi-Square Distribution; Chronic Disease; Colitis; Colo | 1998 |
Enzyme abnormalities in the porphyrias.
Topics: Acute Disease; Aminolevulinic Acid; Chronic Disease; Humans; Hydroxymethylbilane Synthase; Porphyria | 1977 |
Hexachlorobenzene porphyria in rats as a model for human chronic hepatic porphyrias.
Topics: Aminolevulinic Acid; Animals; Chlorobenzenes; Chronic Disease; Coproporphyrins; Disease Models, Anim | 1976 |
[Chromosome investigations in subjects with occupational lead exposure (author's transl)].
Topics: Aminolevulinic Acid; Chromosome Aberrations; Chronic Disease; Culture Techniques; Humans; Lead; Lead | 1975 |
Conjugation of non-erythroid bilirubin in chronic experimental cholestasis in the dog.
Topics: Aminolevulinic Acid; Animals; Bilirubin; Cholestasis; Chronic Disease; Dogs; Liver; Lymph | 1975 |
Preventive and therapeutic role of vitamin E in chronic plumbism.
Topics: Aminolevulinic Acid; Animals; Biogenic Amines; Brain Chemistry; Chronic Disease; Lead; Lead Poisonin | 1989 |
Effect of vitamin E on delta-aminolevulinic acid dehydratase activity in weanling rabbits with chronic plumbism.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Chronic Disease; Dose-Response Relations | 1974 |