aminolevulinic acid has been researched along with Carcinoma, Intraepithelial in 98 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To confirm the reproducibility of the effectiveness and safety in photodynamic diagnosis of non-muscle-invasive bladder cancer using 5-aminolevulinic acid in a prospective multicenter non-randomized phase III trial." | 9.27 | Oral 5-aminolevulinic acid-mediated photodynamic diagnosis using fluorescence cystoscopy for non-muscle-invasive bladder cancer: A multicenter phase III study. ( Fujimoto, K; Furuse, H; Inoue, K; Matsuyama, H; Miyake, M; Nagao, K; Nakai, Y; Oyama, M; Ozono, S; Shimamoto, T; Shuin, T; Tsuzuki, T, 2018) |
| "We determined whether neoplastic disease, which was missed under white light can be found during transurethral resection of bladder cancer by 5-aminolevulinic acid-induced porphyrin fluorescence." | 9.09 | Transurethral resection and surveillance of bladder cancer supported by 5-aminolevulinic acid-induced fluorescence endoscopy. ( Baumgartner, R; Hofstetter, A; Knuechel, R; Kriegmair, M; Stepp, H; Zaak, D, 1999) |
| "5-Aminolevulinic acid facilitates detection of neoplastic disease during transurethral resection of bladder cancer and increases the accuracy of diagnosis." | 9.09 | Transurethral resection and surveillance of bladder cancer supported by 5-aminolevulinic acid-induced fluorescence endoscopy. ( Baumgartner, R; Hofstetter, A; Knuechel, R; Kriegmair, M; Stepp, H; Zaak, D, 1999) |
| "5-aminolevulinic acid mediated changes in tissue specific fluorescence were studied in bladder cancer." | 7.72 | Fluorescence confocal microscopy and image analysis of bladder cancer using 5-aminolevulinic acid. ( Christopher, C; Hoon, TP; Lau, W; Manivasager, V; Olivo, M, 2003) |
| "We determined whether the sensitivity of detecting dysplasia or early bladder cancer can be improved by 5-aminolevulinic acid induced porphyrin fluorescence." | 7.69 | Detection of early bladder cancer by 5-aminolevulinic acid induced porphyrin fluorescence. ( Baumgartner, R; Hofstädter, F; Hofstetter, A; Knüchel, R; Kriegmair, M; Stepp, H, 1996) |
| "5-Aminolevulinic acid (20 mg/kg) was orally administered 3 h before transurethral resection of bladder tumors using white light or fluorescent light." | 6.87 | Oral 5-aminolevulinic acid-mediated photodynamic diagnosis using fluorescence cystoscopy for non-muscle-invasive bladder cancer: A multicenter phase III study. ( Fujimoto, K; Furuse, H; Inoue, K; Matsuyama, H; Miyake, M; Nagao, K; Nakai, Y; Oyama, M; Ozono, S; Shimamoto, T; Shuin, T; Tsuzuki, T, 2018) |
| "Evaluation of residual tumor rate and recurrence free survival were defined as the two primary study endpoints." | 6.71 | [Reducing the risk of superficial bladder cancer recurrence with 5-aminolevulinic acid-induced fluorescence diagnosis. Results of a 5-year study]. ( Filbeck, T; Knuechel, R; Pichlmeier, U; Rössler, W; Wieland, WF, 2003) |
| "Urine samples from 58 patients with bladder cancer were centrifuged, and urine sediments were then treated with ALA." | 5.40 | Diagnostic approach for cancer cells in urine sediments by 5-aminolevulinic acid-based photodynamic detection in bladder cancer. ( Anai, S; Chihara, Y; Fujimoto, K; Hirao, Y; Kuwada, M; Miyake, M; Nakai, Y; Onishi, S; Tanaka, N; Tatsumi, Y, 2014) |
| "Most lesions of superficial bladder cancer may be easily missed during conventional white light cystoscopy." | 5.31 | Significance of fluorescence cystoscopy for diagnosis of superficial bladder cancer after intravesical instillation of delta aminolevulinic acid. ( Ehsan, A; Engelmann, U; Haupt, G; Sommer, F, 2001) |
| "To confirm the reproducibility of the effectiveness and safety in photodynamic diagnosis of non-muscle-invasive bladder cancer using 5-aminolevulinic acid in a prospective multicenter non-randomized phase III trial." | 5.27 | Oral 5-aminolevulinic acid-mediated photodynamic diagnosis using fluorescence cystoscopy for non-muscle-invasive bladder cancer: A multicenter phase III study. ( Fujimoto, K; Furuse, H; Inoue, K; Matsuyama, H; Miyake, M; Nagao, K; Nakai, Y; Oyama, M; Ozono, S; Shimamoto, T; Shuin, T; Tsuzuki, T, 2018) |
| "5 hours after intravesical administration of 17% 5-aminolevulinic acid in 12 patients with recurring, multifocal, Stage pTa, grade I to III, urothelial tumors of the bladder and carcinoma in situ." | 5.10 | Whole bladder photodynamic therapy with 5-aminolevulinic acid using a white light source. ( Baumgartner, R; Beyer, W; Hofstetter, A; Knüchel, R; Kriegmair, M; Schröder, J; Stepp, H; Waidelich, R, 2003) |
| "Our preliminary data show that whole bladder photodynamic therapy with intravesically applied 5-aminolevulinic acid using a white light source is effective in destroying flat malignant lesions of the bladder such as carcinoma in situ." | 5.10 | Whole bladder photodynamic therapy with 5-aminolevulinic acid using a white light source. ( Baumgartner, R; Beyer, W; Hofstetter, A; Knüchel, R; Kriegmair, M; Schröder, J; Stepp, H; Waidelich, R, 2003) |
| "5-Aminolevulinic acid facilitates detection of neoplastic disease during transurethral resection of bladder cancer and increases the accuracy of diagnosis." | 5.09 | Transurethral resection and surveillance of bladder cancer supported by 5-aminolevulinic acid-induced fluorescence endoscopy. ( Baumgartner, R; Hofstetter, A; Knuechel, R; Kriegmair, M; Stepp, H; Zaak, D, 1999) |
| "We determined whether neoplastic disease, which was missed under white light can be found during transurethral resection of bladder cancer by 5-aminolevulinic acid-induced porphyrin fluorescence." | 5.09 | Transurethral resection and surveillance of bladder cancer supported by 5-aminolevulinic acid-induced fluorescence endoscopy. ( Baumgartner, R; Hofstetter, A; Knuechel, R; Kriegmair, M; Stepp, H; Zaak, D, 1999) |
| "Photodynamic therapy (PDT) has been reported as a treatment for cutaneous squamous cell carcinoma in situ (SCCis), but only limited data are available on the effectiveness of PDT with aminolevulinic acid (ALA-PDT)." | 3.96 | Photodynamic therapy for cutaneous squamous cell carcinoma in situ: Impact of anatomic location, tumor diameter, and incubation time on effectiveness. ( Christensen, SR; Kibbi, N; Leffell, DJ; Zhang, Y, 2020) |
| "To investigate the diagnostic accuracy of 5- aminolevulinic acid-mediated photodynamic diagnosis (ALA-PDD) for upper urinary tract tumor (UTUC) including carcinoma in situ (CIS) lesions using flexible fluorescence ureterorenoscopy." | 3.96 | 5-aminolevulinic acid-mediated photodynamic diagnosis using fluorescence ureterorenoscopy for urinary upper tract urothelial carcinoma ∼Preliminary prospective single centre trial∼. ( Fukuhara, H; Furihata, M; Inoue, K; Kurabayashi, A; Murakami, K; Setuda, S; Takahashi, K; Tanaka, T, 2020) |
| "Sixty specimens of bladder mucosa were collected from 20 patients who were suspected of having carcinoma in situ by fluorescence cystoscopy with 5-aminolevulinic acid." | 3.75 | Cytogenetic analysis of false-positive mucosa by photodynamic diagnosis using 5-aminolevulinic acid - possible existence of premalignant genomic alterations examined by in vitro experiment. ( Matsuyama, H; Nagao, K; Ohmi, C; Sakano, S; Sasaki, K; Yamamoto, Y, 2009) |
| "5-aminolevulinic acid mediated changes in tissue specific fluorescence were studied in bladder cancer." | 3.72 | Fluorescence confocal microscopy and image analysis of bladder cancer using 5-aminolevulinic acid. ( Christopher, C; Hoon, TP; Lau, W; Manivasager, V; Olivo, M, 2003) |
| "We determined whether the sensitivity of detecting dysplasia or early bladder cancer can be improved by 5-aminolevulinic acid induced porphyrin fluorescence." | 3.69 | Detection of early bladder cancer by 5-aminolevulinic acid induced porphyrin fluorescence. ( Baumgartner, R; Hofstädter, F; Hofstetter, A; Knüchel, R; Kriegmair, M; Stepp, H, 1996) |
| "Current treatments of high-grade squamous intraepithelial lesion (HSIL) of the cervix are based on invasive surgical interventions, compromising cervical competence and functionality." | 3.11 | Multicentre, prospective, randomised controlled trial to evaluate hexaminolevulinate photodynamic therapy (Cevira) as a novel treatment in patients with high-grade squamous intraepithelial lesion: APRICITY phase 3 study protocol. ( Chen, F; Dannecker, C; Han, L; Hillemanns, P; Lang, J; Mokráš, C; Novák, Z; Sui, L; You, Z; Zhang, Y, 2022) |
| "5-Aminolevulinic acid (20 mg/kg) was orally administered 3 h before transurethral resection of bladder tumors using white light or fluorescent light." | 2.87 | Oral 5-aminolevulinic acid-mediated photodynamic diagnosis using fluorescence cystoscopy for non-muscle-invasive bladder cancer: A multicenter phase III study. ( Fujimoto, K; Furuse, H; Inoue, K; Matsuyama, H; Miyake, M; Nagao, K; Nakai, Y; Oyama, M; Ozono, S; Shimamoto, T; Shuin, T; Tsuzuki, T, 2018) |
| " In this study, we evaluated the feasibility and efficacy of aminolevulinic acid (ALA) as a photosensitizer (ALA-PDT) in combination with CO2 laser in the treatment of Bowen's disease (BD; intraepithelial squamous cell carcinoma)." | 2.80 | Photodynamic therapy in combination with CO2 laser for the treatment of Bowen's disease. ( Cai, H; Li, Q; Li, YL; Liu, W; Liu, XY; Sun, P; Wang, YX; Yang, ZY; Zheng, JC, 2015) |
| "Recurrent bladder cancer was confirmed histologically in 14/18 (78%) patients." | 2.74 | Hexylaminolevulinate photodynamic diagnosis for multifocal recurrent nonmuscle invasive bladder cancer. ( Chandra, A; Chatterton, K; Khan, MS; O'Brien, TS; Ray, ER; Thomas, K, 2009) |
| "In patients with bladder cancer hexaminolevulinate fluorescence cystoscopy with blue light can diagnose carcinoma in situ that may be missed with white light cystoscopy." | 2.73 | A comparison of hexaminolevulinate fluorescence cystoscopy and white light cystoscopy for the detection of carcinoma in situ in patients with bladder cancer: a phase III, multicenter study. ( Albala, D; Cookson, M; Droller, MJ; Fradet, Y; Gomella, L; Grossman, HB; Lerner, S, 2007) |
| "5-Aminolevulinic acid (5-ALA) is a useful agent to enhance the detection of early epithelial lesions in head and neck cancers." | 2.71 | Excretion measurement of porphyrins and their precursors after topical administration of 5-aminolaevulinic acid for fluorescence endoscopy in head and neck cancer. ( Brossmann, P; Doss, MO; Gross, U; Klahr, N; Klein, M; Külkens, C; Lippert, BM; Ney, M; Teymoortash, A; Werner, JA, 2003) |
| "Evaluation of residual tumor rate and recurrence free survival were defined as the two primary study endpoints." | 2.71 | [Reducing the risk of superficial bladder cancer recurrence with 5-aminolevulinic acid-induced fluorescence diagnosis. Results of a 5-year study]. ( Filbeck, T; Knuechel, R; Pichlmeier, U; Rössler, W; Wieland, WF, 2003) |
| "A major problem diagnosing bladder cancer using conventional white-light cystoscopy is that flat and tiny papillary neoplasms can be overlooked." | 2.70 | Diagnostic efficacy of fluorescence cystoscopy for detection of urothelial neoplasms. ( Chai, SE; Choi, HY; Hong, JH; Jeon, SS; Kang, I, 2001) |
| "A series of 62 patients with suspected bladder cancer were investigated by fluorescence cystoscopy." | 2.70 | Diagnostic efficacy of fluorescence cystoscopy for detection of urothelial neoplasms. ( Chai, SE; Choi, HY; Hong, JH; Jeon, SS; Kang, I, 2001) |
| "Bladder cancer is the most common tumor of the urinary tract, with a worldwide incidence of 8." | 2.49 | Innovations in the endoscopic management of bladder cancer: is the era of white light cystoscopy over. ( Ambrosini, E; Frea, B; Giona, S; Gontero, P; Gurioli, A; Oderda, M; Peraldo, F; Soria, F, 2013) |
| "Bladder cancer is a frequent disease and represents the second most common genitourinary neoplasm." | 2.44 | [Fluorescence cystoscopy at bladder cancer: present trials]. ( Burger, M; Karl, A; Knuechel, R; Stepp, H; Stief, C; Tilki, D; Tritschler, S; Zaak, D, 2007) |
| "In flat bladder cancer and carcinoma in situ, and in multifocal papillary cancer, some smaller lesions may be overlooked at cystoscopy." | 2.44 | Recent developments in fluorescence cystoscopy: do novel agents bring a benefit? ( Marberger, M; Schmidbauer, J, 2007) |
| "With regard to bladder cancer, advances in drug development and modern light delivery techniques mean that photodynamic therapy shows promise in the treatment of superficial bladder cancer resistant to conventional treatments." | 2.41 | Photodynamic therapy for superficial bladder cancer. ( Betts, CD; Briggs, C; Clarke, NW; Moore, JV; O'Flynn, KJ; Shackley, DC; Whitehurst, C, 2001) |
| "It was also observed that persistent HPV infection is a major risk factor for persistent disease." | 1.72 | Comparative study of topical 5-aminolevulinic acid photodynamic therapy (5-ALA-PDT) and surgery for the treatment of high-grade vaginal intraepithelial neoplasia. ( Cao, L; Qin, L; Shen, Y; Su, Y; Tang, Y; Wang, B; Zhang, M; Zhang, T; Zhang, Y; Zhou, M; Zhou, Y, 2022) |
| " The most common adverse event was increased vaginal discharge, other side effects include abdominal pain, vulvar pruritus, and vaginal bleeding." | 1.72 | Efficacy and safety of photodynamic therapy mediatied by 5-aminolevulinic acid for the treatment of vaginal high-grade intraepithelial lesions. ( Guo, H; Han, Q; Wu, Z; Zhang, X, 2022) |
| "Photodynamic therapy mediatied by 5-aminolevulinic acid is an effective and safe treatment for vaginal HSIL with minimal side effects." | 1.72 | Efficacy and safety of photodynamic therapy mediatied by 5-aminolevulinic acid for the treatment of vaginal high-grade intraepithelial lesions. ( Guo, H; Han, Q; Wu, Z; Zhang, X, 2022) |
| "To evaluate the residual tumor rate, the bladder was inspected after its removal and normal appearing mucosa sampled for histologic analysis." | 1.46 | Diagnostic Accuracy of Hexaminolevulinate in a Cohort of Patients Undergoing Radical Cystectomy. ( Alba, S; Buscarini, M; Carrieri, G; Cormio, L; Di Stasi, S; Gallone, MF; Minafra, P; Pagliarulo, V; Petitti, T, 2017) |
| "Urine samples from 58 patients with bladder cancer were centrifuged, and urine sediments were then treated with ALA." | 1.40 | Diagnostic approach for cancer cells in urine sediments by 5-aminolevulinic acid-based photodynamic detection in bladder cancer. ( Anai, S; Chihara, Y; Fujimoto, K; Hirao, Y; Kuwada, M; Miyake, M; Nakai, Y; Onishi, S; Tanaka, N; Tatsumi, Y, 2014) |
| "ALA-PDT can ablate anal mucosa and peri-anal skin with safe healing and no underlying damage." | 1.39 | Safe ablation of the anal mucosa and perianal skin in rats using Photodynamic Therapy--a promising approach for treating Anal Intraepithelial Neoplasia. ( Abbasakoor, F; Boulos, P; Bown, S; Farooqui, N; MacRobert, A; Novelli, M; Woodhams, J, 2013) |
| " Photodynamic Therapy (PDT) is promising as it is known to ablate more proximal gastrointestinal mucosa with safe healing, without damage to underlying muscle." | 1.39 | Safe ablation of the anal mucosa and perianal skin in rats using Photodynamic Therapy--a promising approach for treating Anal Intraepithelial Neoplasia. ( Abbasakoor, F; Boulos, P; Bown, S; Farooqui, N; MacRobert, A; Novelli, M; Woodhams, J, 2013) |
| "In patients with non-muscle invasive bladder cancer, fluorescence cystoscopy can improve the detection and ablation of bladder tumors." | 1.38 | Blue light cystoscopy for detection and treatment of non-muscle invasive bladder cancer. ( Gelpi-Hammerschmidt, F; Gomella, LG; Mark, JR; Trabulsi, EJ, 2012) |
| "PDD during initial TUR-BT in T1G3 bladder cancer seems to reduce significantly the rate of recurrence in our study population." | 1.36 | Photodynamic diagnosis in patients with T1G3 bladder cancer: influence on recurrence rate. ( Karl, A; Knüchel, R; Stadler, T; Stanislaus, P; Stief, CG; Tritschler, S; Zaak, D, 2010) |
| "In conclusion, photodynamic therapy for extramammary Paget's disease is not recommended as the first option except for scrotal cases or lesions < 4 cm in diameter." | 1.36 | Long-term follow-up of in situ extramammary Paget's disease in Asian skin types IV/V treated with photodynamic therapy. ( Gao, T; Hu, X; Jiao, B; Li, C; Li, Q; Liao, W; Long, HA; Lv, Y; Qi, X; Qiao, H; Wang, L; Wang, S, 2010) |
| "We evaluated the clinical response, recurrence and adverse events of photodynamic therapy for in situ extramammary Paget's disease in 14 male and 3 female Chinese patients with 21 lesions." | 1.36 | Long-term follow-up of in situ extramammary Paget's disease in Asian skin types IV/V treated with photodynamic therapy. ( Gao, T; Hu, X; Jiao, B; Li, C; Li, Q; Liao, W; Long, HA; Lv, Y; Qi, X; Qiao, H; Wang, L; Wang, S, 2010) |
| "Vulvar cancer is a rare (accounting for about 2,5-5% of all malignant neoplasms), female genital organs cancer." | 1.35 | [Photodynamic therapy in vulvar intraepithelial neoplasia]. ( Biniszkiewicz, T; Kellas-Sleczka, S; Kozak-Darmas, I; Olejek, A; Sieroń, A, 2008) |
| " This approach makes ALA dosing difficult and delivery to demanding areas, such as the vulval, perineal and perianal skin, are seldom possible." | 1.33 | Design and evaluation of a water-soluble bioadhesive patch formulation for cutaneous delivery of 5-aminolevulinic acid to superficial neoplastic lesions. ( Donnelly, RF; McCarron, PA; Woolfson, AD; Zawislak, A, 2006) |
| "Barrett's esophagus is strongly associated with adenocarcinoma." | 1.32 | Endoscopic fluorescence detection of intraepithelial neoplasia in Barrett's esophagus after oral administration of aminolevulinic acid. ( Dorta, G; Felley, C; Fontolliet, C; Gabrecht, T; Grosjean, P; Jornod, P; Lange, N; Monnier, P; Stepinac, T; van den Bergh, H; vanMelle, G; Wagnières, G, 2003) |
| "A total of 279 patients with suspected bladder tumors underwent transurethral resection using FD in addition to WL cystoscopy." | 1.31 | Do patients profit from 5-aminolevulinic acid-induced fluorescence diagnosis in transurethral resection of bladder carcinoma? ( Filbeck, T; Knuechel, R; Pichlmeier, U; Roessler, W; Wieland, WF, 2002) |
| "This was first shown for cancer of the bladder." | 1.31 | [Fluorescent endoscopy superior to white light endoscopy. Detecting cancers of the urinary bladder earlier]. ( Zaak, D, 2002) |
| "24 patients suffering from oral cancer were included in this investigation." | 1.31 | Fluorescence staining of oral cancer using a topical application of 5-aminolevulinic acid: fluorescence microscopic studies. ( Arbogast, S; Baumgartner, R; Betz, C; Grevers, G; Leunig, A; Mehlmann, M; Stepp, H, 2001) |
| "Most lesions of superficial bladder cancer may be easily missed during conventional white light cystoscopy." | 1.31 | Significance of fluorescence cystoscopy for diagnosis of superficial bladder cancer after intravesical instillation of delta aminolevulinic acid. ( Ehsan, A; Engelmann, U; Haupt, G; Sommer, F, 2001) |
| "Sixteen patients with papillary bladder cancer, and CIS and dysplasia were given low-dose ALA." | 1.30 | Fluorescence detection of flat transitional cell carcinoma after intravesical instillation of aminolevulinic acid. ( Baert, L; D'Hallewin, MA; Vanherzeele, H, 1998) |
| "Erythroplasia of Queyrat (EQ) is an intraepithelial carcinoma in situ affecting the mucosal surfaces of the penis, with a significant risk of invasion and metastasis." | 1.30 | Erythroplasia of Queyrat treated by topical aminolaevulinic acid photodynamic therapy. ( Ash, DV; Robinson, DJ; Stables, GI; Stringer, MR, 1999) |
| "The prognosis of superficial bladder cancer in terms of local recurrence and transformation into invasive cancer is related to the multiplicity of tumor sites and the concomitant presence of "flat" tumours, such as dysplasia and carcinoma in situ." | 1.30 | [The clinical value of fluorescence cystoscopy in the detection of superficial transitional epithelial cell carcinoma of the bladder]. ( Forrer, M; Graber, P; Guillou, L; Jichlinski, P; Leisinger, HJ; Mizeret, J; Schmidlin, F; Van den Bergh, H; Wagniéres, G, 1997) |
| "Following transurethral resection of bladder cancer, the fate of patients is clearly related to the presence or absence of precancerous or malignant lesions in the remaining mucosa." | 1.29 | [Photodynamic diagnosis of urothelial neoplasms after intravesicular instillation of 5-aminolevulinic acid]. ( Baumgartner, R; Ehsan, A; Hofstädter, F; Hofstetter, A; Knüchel, R; Kriegmair, M; Lumper, W; Steinbach, P, 1994) |
| "5-Aminolevulinic acid was instilled prior to cystoscopy and biopsies were taken of lesions that were either fluorescing or nonfluorescing." | 1.29 | Intravesical instillation of 5-aminolevulinic acid: the fluorescent metabolite is limited to urothelial cells. ( Baumgartner, R; Hofstädter, F; Knüchel, R; Kriegmair, M; Steinbach, P, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (11.22) | 18.2507 |
| 2000's | 52 (53.06) | 29.6817 |
| 2010's | 24 (24.49) | 24.3611 |
| 2020's | 11 (11.22) | 2.80 |
| Authors | Studies |
|---|---|
| Han, Q | 1 |
| Wu, Z | 1 |
| Guo, H | 1 |
| Zhang, X | 1 |
| Chen, F | 1 |
| Novák, Z | 1 |
| Dannecker, C | 3 |
| Mokráš, C | 1 |
| Sui, L | 1 |
| Zhang, Y | 4 |
| You, Z | 1 |
| Han, L | 1 |
| Lang, J | 1 |
| Hillemanns, P | 4 |
| Su, Y | 1 |
| Tang, Y | 1 |
| Qin, L | 1 |
| Shen, Y | 1 |
| Wang, B | 1 |
| Zhou, M | 1 |
| Zhou, Y | 1 |
| Cao, L | 1 |
| Zhang, T | 1 |
| Zhang, M | 2 |
| Hu, X | 2 |
| He, Y | 1 |
| Lin, L | 1 |
| Li, X | 1 |
| Luo, X | 1 |
| Wang, L | 2 |
| Xu, C | 1 |
| Wu, D | 1 |
| Wang, S | 2 |
| Zuo, M | 1 |
| Li, D | 1 |
| Chen, W | 1 |
| Sha, M | 1 |
| Yuan, L | 1 |
| Qin, N | 1 |
| Zhao, S | 2 |
| Liu, D | 2 |
| Shi, W | 2 |
| Kang, Y | 1 |
| Li, Q | 3 |
| Liu, Q | 1 |
| Chen, M | 2 |
| Li, F | 1 |
| Su, J | 2 |
| Wu, L | 2 |
| Kibbi, N | 1 |
| Leffell, DJ | 1 |
| Christensen, SR | 1 |
| Drejer, D | 1 |
| Moltke, AL | 1 |
| Nielsen, AM | 1 |
| Lam, GW | 1 |
| Jensen, JB | 1 |
| Fukuhara, H | 1 |
| Kurabayashi, A | 1 |
| Furihata, M | 1 |
| Setuda, S | 1 |
| Takahashi, K | 1 |
| Murakami, K | 1 |
| Tanaka, T | 1 |
| Inoue, K | 2 |
| Yu, N | 1 |
| Huang, K | 1 |
| Zhou, Q | 1 |
| Lu, L | 1 |
| Andersson, M | 1 |
| Berger, M | 1 |
| Zieger, K | 1 |
| Malmström, PU | 2 |
| Bläckberg, M | 1 |
| Nakai, Y | 2 |
| Tsuzuki, T | 1 |
| Shimamoto, T | 1 |
| Shuin, T | 1 |
| Nagao, K | 2 |
| Matsuyama, H | 3 |
| Oyama, M | 1 |
| Furuse, H | 1 |
| Ozono, S | 1 |
| Miyake, M | 2 |
| Fujimoto, K | 2 |
| Konecki, T | 1 |
| Kutwin, P | 1 |
| Łowicki, R | 1 |
| Juszczak, AB | 1 |
| Jabłonowski, Z | 1 |
| Burger, M | 3 |
| Grossman, HB | 3 |
| Droller, M | 1 |
| Schmidbauer, J | 3 |
| Hermann, G | 1 |
| Drăgoescu, O | 1 |
| Ray, E | 1 |
| Fradet, Y | 3 |
| Karl, A | 3 |
| Burgués, JP | 1 |
| Witjes, JA | 1 |
| Stenzl, A | 1 |
| Jichlinski, P | 4 |
| Jocham, D | 2 |
| Cinotti, E | 1 |
| Perrot, JL | 1 |
| Labeille, B | 1 |
| Douchet, C | 1 |
| Mottet, N | 1 |
| Cambazard, F | 1 |
| Soria, F | 1 |
| Gurioli, A | 1 |
| Peraldo, F | 1 |
| Oderda, M | 1 |
| Giona, S | 1 |
| Ambrosini, E | 1 |
| Frea, B | 1 |
| Gontero, P | 1 |
| Welbourn, H | 1 |
| Duthie, G | 1 |
| Powell, J | 1 |
| Moghissi, K | 1 |
| Abbasakoor, F | 1 |
| Woodhams, J | 1 |
| Farooqui, N | 1 |
| Novelli, M | 1 |
| Bown, S | 1 |
| MacRobert, A | 1 |
| Boulos, P | 1 |
| Anai, S | 1 |
| Tatsumi, Y | 1 |
| Kuwada, M | 1 |
| Onishi, S | 1 |
| Chihara, Y | 1 |
| Tanaka, N | 1 |
| Hirao, Y | 1 |
| Cai, H | 1 |
| Wang, YX | 1 |
| Zheng, JC | 1 |
| Sun, P | 1 |
| Yang, ZY | 1 |
| Li, YL | 1 |
| Liu, XY | 1 |
| Liu, W | 1 |
| Sfetsas, K | 1 |
| Mitropoulos, D | 1 |
| Bach, T | 1 |
| Bastian, PJ | 1 |
| Blana, A | 1 |
| Kaminsky, A | 1 |
| Keller, S | 1 |
| Knoll, T | 1 |
| Lang, C | 1 |
| Promnitz, S | 1 |
| Ubrig, B | 1 |
| Keller, T | 1 |
| Qvick, B | 1 |
| Pagliarulo, V | 1 |
| Alba, S | 1 |
| Gallone, MF | 1 |
| Di Stasi, S | 1 |
| Cormio, L | 1 |
| Petitti, T | 1 |
| Buscarini, M | 1 |
| Minafra, P | 1 |
| Carrieri, G | 1 |
| Olejek, A | 2 |
| Kozak-Darmas, I | 1 |
| Biniszkiewicz, T | 2 |
| Kellas-Sleczka, S | 1 |
| Sieroń, A | 2 |
| Ray, ER | 2 |
| Chatterton, K | 2 |
| Khan, MS | 2 |
| Thomas, K | 2 |
| Chandra, A | 2 |
| O'Brien, TS | 2 |
| Calista, D | 1 |
| Coccia, L | 1 |
| Yamamoto, Y | 1 |
| Ohmi, C | 1 |
| Sakano, S | 1 |
| Sasaki, K | 1 |
| Gomella, LG | 2 |
| Mostafid, H | 1 |
| Bunce, C | 1 |
| Gao, T | 1 |
| Jiao, B | 1 |
| Qi, X | 1 |
| Long, HA | 1 |
| Qiao, H | 1 |
| Lv, Y | 1 |
| Liao, W | 1 |
| Li, C | 1 |
| Stanislaus, P | 1 |
| Zaak, D | 7 |
| Stadler, T | 1 |
| Tritschler, S | 2 |
| Knüchel, R | 6 |
| Stief, CG | 1 |
| Lin, HP | 1 |
| Chen, HM | 1 |
| Yu, CH | 1 |
| Yang, H | 1 |
| Wang, YP | 1 |
| Chiang, CP | 1 |
| Ballester, I | 1 |
| Belinchón, I | 1 |
| Guijarro, J | 1 |
| Oltra, F | 1 |
| Toledo, F | 1 |
| Cuesta, L | 1 |
| Compérat, E | 1 |
| Conort, P | 1 |
| Rouprêt, M | 1 |
| Camparo, P | 1 |
| Mazerolles, C | 1 |
| Jerjes, W | 1 |
| Upile, T | 1 |
| Hamdoon, Z | 1 |
| Mosse, CA | 1 |
| Akram, S | 1 |
| Hopper, C | 1 |
| Daayana, S | 1 |
| Winters, U | 1 |
| Stern, PL | 1 |
| Kitchener, HC | 2 |
| Isfoss, BL | 1 |
| Vom Dorp, F | 1 |
| Tschirdewahn, S | 1 |
| Olbricht, T | 1 |
| Szarvas, T | 1 |
| Rübben, H | 1 |
| Kamradt, J | 1 |
| Ohlmann, CH | 1 |
| Stöckle, M | 1 |
| Mark, JR | 1 |
| Gelpi-Hammerschmidt, F | 1 |
| Trabulsi, EJ | 1 |
| Shackley, DC | 1 |
| Briggs, C | 1 |
| Whitehurst, C | 2 |
| Betts, CD | 1 |
| O'Flynn, KJ | 1 |
| Clarke, NW | 1 |
| Moore, JV | 2 |
| Marti, A | 1 |
| Leisinger, HJ | 3 |
| Hungerhuber, E | 2 |
| Schneede, P | 3 |
| Stepp, H | 10 |
| Frimberger, D | 1 |
| Corvin, S | 1 |
| Schmeller, N | 3 |
| Kriegmair, M | 6 |
| Hofstetter, A | 8 |
| Knuechel, R | 7 |
| Knöchel, R | 1 |
| D'Hallewin, MA | 2 |
| Bezdetnaya, L | 1 |
| Guillemin, F | 1 |
| Filbeck, T | 3 |
| Pichlmeier, U | 2 |
| Wieland, WF | 3 |
| Roessler, W | 2 |
| Olivo, M | 1 |
| Lau, W | 1 |
| Manivasager, V | 1 |
| Hoon, TP | 1 |
| Christopher, C | 1 |
| Waidelich, R | 3 |
| Beyer, W | 1 |
| Baumgartner, R | 8 |
| Schröder, J | 1 |
| Tauber, S | 3 |
| Liedl, B | 2 |
| Liesmann, F | 1 |
| Guillou, L | 2 |
| Karlsen, SJ | 1 |
| Brennhovd, B | 1 |
| Johansson, E | 1 |
| Gärtner, T | 1 |
| Lange, N | 2 |
| van den Bergh, H | 3 |
| Stepinac, T | 1 |
| Felley, C | 1 |
| Jornod, P | 1 |
| Gabrecht, T | 1 |
| Fontolliet, C | 1 |
| Grosjean, P | 1 |
| vanMelle, G | 1 |
| Monnier, P | 1 |
| Wagnières, G | 2 |
| Dorta, G | 1 |
| Rössler, W | 1 |
| Hamdan, KA | 1 |
| Tait, IS | 1 |
| Nadeau, V | 1 |
| Padgett, M | 1 |
| Carey, F | 1 |
| Steele, RJ | 1 |
| Witjes, F | 1 |
| Donat, R | 1 |
| Susani, M | 1 |
| Marberger, M | 2 |
| Akoel, KM | 1 |
| Welfel, J | 1 |
| Gottwald, L | 1 |
| Suzin, J | 1 |
| Marmur, ES | 1 |
| Schmults, CD | 1 |
| Goldberg, DJ | 1 |
| Endlicher, E | 1 |
| Gelbmann, CM | 1 |
| Fürst, A | 1 |
| Szeimies, RM | 1 |
| Gölder, SK | 1 |
| Schölmerich, J | 1 |
| Lottner, C | 1 |
| Messmann, H | 1 |
| Scholefield, JH | 1 |
| Lippert, BM | 1 |
| Gross, U | 1 |
| Klein, M | 1 |
| Külkens, C | 1 |
| Klahr, N | 1 |
| Brossmann, P | 1 |
| Teymoortash, A | 1 |
| Ney, M | 1 |
| Doss, MO | 1 |
| Werner, JA | 1 |
| Wang, X | 1 |
| Staehle, S | 1 |
| Michels, W | 1 |
| Daniltchenko, DI | 1 |
| Riedl, CR | 1 |
| Sachs, MD | 1 |
| Koenig, F | 1 |
| Daha, KL | 1 |
| Pflueger, H | 1 |
| Loening, SA | 1 |
| Schnorr, D | 1 |
| McCarron, PA | 2 |
| Donnelly, RF | 1 |
| Zawislak, A | 1 |
| Woolfson, AD | 1 |
| Ma, LW | 1 |
| Juzenas, P | 1 |
| Lani, V | 1 |
| Woolfson, A | 1 |
| Zawislak, AA | 1 |
| Moan, J | 1 |
| Frampton, JE | 1 |
| Plosker, GL | 1 |
| Perrett, CM | 1 |
| McGregor, JM | 1 |
| Warwick, J | 1 |
| Karran, P | 1 |
| Leigh, IM | 1 |
| Proby, CM | 1 |
| Harwood, CA | 1 |
| Gomella, L | 2 |
| Morales, A | 1 |
| Presti, J | 1 |
| Ritenour, C | 1 |
| Nseyo, U | 1 |
| Droller, MJ | 2 |
| Lerner, S | 1 |
| Cookson, M | 1 |
| Albala, D | 1 |
| Tilki, D | 1 |
| Stief, C | 1 |
| Forster, TH | 1 |
| Wyler, S | 1 |
| Ruszat, R | 1 |
| Gasser, TC | 1 |
| Bachmann, A | 1 |
| Hofstädter, F | 3 |
| Lui, H | 1 |
| Salasche, S | 1 |
| Kollias, N | 1 |
| Wimberly, J | 1 |
| Flotte, T | 1 |
| McLean, D | 1 |
| Anderson, RR | 1 |
| Ehsan, A | 2 |
| Steinbach, P | 2 |
| Lumper, W | 1 |
| Forrer, M | 1 |
| Mizeret, J | 1 |
| Schmidlin, F | 1 |
| Graber, P | 1 |
| Martin-Hirsch, PL | 1 |
| Buckley, CH | 1 |
| Vanherzeele, H | 1 |
| Baert, L | 1 |
| Petrík, R | 1 |
| Jirsa, M | 1 |
| Dvorák, E | 1 |
| Skoda, V | 1 |
| Stádník, B | 1 |
| Straub, M | 1 |
| Kiel, HJ | 1 |
| Stables, GI | 1 |
| Stringer, MR | 1 |
| Robinson, DJ | 1 |
| Ash, DV | 1 |
| Untch, M | 1 |
| Diebold, J | 1 |
| Weingandt, H | 2 |
| Pröve, F | 1 |
| Korell, M | 1 |
| Kurwa, HA | 1 |
| Barlow, RJ | 1 |
| Neill, S | 1 |
| Fehr, MK | 1 |
| Hornung, R | 1 |
| Schwarz, VA | 1 |
| Simeon, R | 1 |
| Haller, U | 1 |
| Wyss, P | 1 |
| Urban, A | 1 |
| Drebkowski, A | 1 |
| Guillen, C | 1 |
| Sanmartin, O | 1 |
| Escudero, A | 1 |
| Botella-Estrada, R | 1 |
| Sevila, A | 1 |
| Castejon, P | 1 |
| De Dominicis, C | 1 |
| Liberti, M | 1 |
| Perugia, G | 1 |
| De Nunzio, C | 1 |
| Sciobica, F | 1 |
| Zuccalà, A | 1 |
| Sarkozy, A | 1 |
| Iori, F | 1 |
| Leunig, A | 1 |
| Mehlmann, M | 1 |
| Betz, C | 1 |
| Arbogast, S | 1 |
| Grevers, G | 1 |
| Liessmann, F | 2 |
| Xiang, W | 1 |
| Klein, S | 1 |
| Jeon, SS | 1 |
| Kang, I | 1 |
| Hong, JH | 1 |
| Choi, HY | 1 |
| Chai, SE | 1 |
| Sommer, F | 1 |
| Haupt, G | 1 |
| Engelmann, U | 1 |
| Hartmann, A | 1 |
| Schlake, G | 1 |
| Hofstaedter, F | 1 |
| Pytel, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Double Blind, Prospective, Randomized, Placebo Controlled, Multi-center Phase 3 Study to Evaluate Efficacy and Safety of Cevira® in Patients With Cervical Histologic High-grade Squamous Intraepithelial Lesions (HSIL)[NCT04484415] | Phase 3 | 402 participants (Actual) | Interventional | 2020-11-10 | Active, not recruiting | ||
| The Correlation of Surgical Colorectal Cancer Specimen Pathology With the Fluorescence of Photodynamic Diagnostics (PDD): a Clinical Pilot Study[NCT03272659] | Phase 2 | 0 participants (Actual) | Interventional | 2018-04-01 | Withdrawn (stopped due to Long process and due to strict deadline, project was stopped.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
16 reviews available for aminolevulinic acid and Carcinoma, Intraepithelial
| Article | Year |
|---|---|
Hexaminolevulinate in the Management of Nonmuscle Invasive Bladder Cancer: A Meta-Analysis.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Humans; Neoplasm Invasiveness; Photosensitizing | 2019 |
Photodynamic diagnosis of non-muscle-invasive bladder cancer with hexaminolevulinate cystoscopy: a meta-analysis of detection and recurrence based on raw data.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Humans; Kaplan-Meier Estimate; Neoplasm Invasive | 2013 |
Innovations in the endoscopic management of bladder cancer: is the era of white light cystoscopy over.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell; Cystoscopy; False Negative Rea | 2013 |
[Pathologic diagnosis and management of flat lesions of urothelium detected with aminolevulinic acid (Hexvix®)].
Topics: Aminolevulinic Acid; Carcinoma in Situ; Humans; Metaplasia; Urinary Bladder; Urinary Bladder Neoplas | 2011 |
Clinical and immunological response to photodynamic therapy in the treatment of vulval intraepithelial neoplasia.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Female; Humans; Papillomaviridae; Papillomavirus Infections; | 2011 |
The sensitivity of fluorescent-light cystoscopy for the detection of carcinoma in situ (CIS) of the bladder: a meta-analysis with comments on gold standard.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Fluorescence; Humans; Lighting; Photosensitizing | 2011 |
[Photodynamic diagnostics of bladder carcinoma].
Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell; Cystoscopy; Fluorescence; Huma | 2011 |
[Current developments in the diagnostics and therapy of bladder carcinoma].
Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell; Chemotherapy, Adjuvant; Combin | 2011 |
Photodynamic therapy for superficial bladder cancer.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Dose-Response Relationship, Radiation; Hematoporphyrins; Hum | 2001 |
Fluorescence detection of bladder cancer: a review.
Topics: Administration, Intravesical; Aminolevulinic Acid; Anthracenes; Carcinoma in Situ; Cystoscopy; Dihem | 2002 |
A review of laser and photodynamic therapy for the treatment of nonmelanoma skin cancer.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Basal Cell; Clinical Trials as Topic; Humans; Ker | 2004 |
Recent developments in fluorescence cystoscopy: do novel agents bring a benefit?
Topics: Aminolevulinic Acid; Anthracenes; Carcinoma in Situ; Cystoscopy; Fluorescence; Fluorescent Dyes; Hum | 2007 |
[Fluorescence cystoscopy at bladder cancer: present trials].
Topics: Aminolevulinic Acid; Biopsy; Carcinoma in Situ; Carcinoma, Transitional Cell; Cystoscopy; Fluorescen | 2007 |
["... The better to see you with"--phothodynamic diagnostic in superficial bladder cancer].
Topics: Administration, Intravesical; Aminolevulinic Acid; Animals; Carcinoma in Situ; Carcinoma, Papillary; | 2007 |
[Fluorescence diagnosis and photodynamic therapy in urology].
Topics: Aminolevulinic Acid; Carcinoma in Situ; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II | 2007 |
[Use of photodynamic methods in diagnosis and therapy of epithelial vulvar diseases].
Topics: Aminolevulinic Acid; Carcinoma in Situ; Condylomata Acuminata; Female; Humans; Photochemotherapy; Ph | 2000 |
19 trials available for aminolevulinic acid and Carcinoma, Intraepithelial
| Article | Year |
|---|---|
Multicentre, prospective, randomised controlled trial to evaluate hexaminolevulinate photodynamic therapy (Cevira) as a novel treatment in patients with high-grade squamous intraepithelial lesion: APRICITY phase 3 study protocol.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Clinical Trials, Phase III as Topic; Female; Humans; Multice | 2022 |
DaBlaCa-11: Photodynamic Diagnosis in Flexible Cystoscopy-A Randomized Study With Focus on Recurrence.
Topics: Aged; Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Female; Humans; Image Enhancement; Male; N | 2020 |
Oral 5-aminolevulinic acid-mediated photodynamic diagnosis using fluorescence cystoscopy for non-muscle-invasive bladder cancer: A multicenter phase III study.
Topics: Administration, Oral; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; F | 2018 |
Photodynamic therapy in combination with CO2 laser for the treatment of Bowen's disease.
Topics: Administration, Topical; Adult; Aged; Aminolevulinic Acid; Bowen's Disease; Carcinoma in Situ; Doubl | 2015 |
Hexylaminolevulinate photodynamic diagnosis for multifocal recurrent nonmuscle invasive bladder cancer.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma in Situ; Cystoscopy; Demograp | 2009 |
Photodynamic therapy outcome for oral dysplasia.
Topics: Aged; Aminolevulinic Acid; Carcinoma in Situ; Drug Administration Schedule; Female; Humans; Lasers, | 2011 |
Whole bladder photodynamic therapy with 5-aminolevulinic acid using a white light source.
Topics: Administration, Intravesical; Aminolevulinic Acid; Biopsy; Carcinoma in Situ; Carcinoma, Transitiona | 2003 |
Hexyl aminolevulinate fluorescence cystoscopy: new diagnostic tool for photodiagnosis of superficial bladder cancer--a multicenter study.
Topics: Aged; Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Female; Humans; Male; Middle Aged; Neoplas | 2003 |
[Reducing the risk of superficial bladder cancer recurrence with 5-aminolevulinic acid-induced fluorescence diagnosis. Results of a 5-year study].
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell | 2003 |
Excretion measurement of porphyrins and their precursors after topical administration of 5-aminolaevulinic acid for fluorescence endoscopy in head and neck cancer.
Topics: Administration, Topical; Aged; Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Squamous Cell; Fec | 2003 |
Long-term benefit of 5-aminolevulinic acid fluorescence assisted transurethral resection of superficial bladder cancer: 5-year results of a prospective randomized study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Austria; Carcinoma in Situ; Cystect | 2005 |
Facilitated delivery of ALA to inaccessible regions via bioadhesive patch systems.
Topics: Administration, Topical; Aminolevulinic Acid; Carcinoma in Situ; Drug Delivery Systems; Female; Herp | 2006 |
Treatment of post-transplant premalignant skin disease: a randomized intrapatient comparative study of 5-fluorouracil cream and topical photodynamic therapy.
Topics: Administration, Topical; Aged; Aminolevulinic Acid; Antimetabolites, Antineoplastic; Bowen's Disease | 2007 |
A phase III, multicenter comparison of hexaminolevulinate fluorescence cystoscopy and white light cystoscopy for the detection of superficial papillary lesions in patients with bladder cancer.
Topics: Aged; Aminolevulinic Acid; Carbon Radioisotopes; Carcinoma in Situ; Carcinoma, Transitional Cell; Cy | 2007 |
A comparison of hexaminolevulinate fluorescence cystoscopy and white light cystoscopy for the detection of carcinoma in situ in patients with bladder cancer: a phase III, multicenter study.
Topics: Aged; Aminolevulinic Acid; Carbon Radioisotopes; Carcinoma in Situ; Cystoscopy; Female; Humans; Male | 2007 |
Transurethral resection and surveillance of bladder cancer supported by 5-aminolevulinic acid-induced fluorescence endoscopy.
Topics: Adenocarcinoma, Papillary; Adolescent; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinom | 1999 |
Photodynamic therapy of vulvar intraepithelial neoplasia using 5-aminolevulinic acid.
Topics: Adult; Aged; Aminolevulinic Acid; Carcinoma in Situ; Female; Humans; Middle Aged; Photochemotherapy; | 2000 |
Photodynamic therapy of vulvar intraepithelial neoplasia III using topically applied 5-aminolevulinic acid.
Topics: Administration, Topical; Adult; Aminolevulinic Acid; Carcinoma in Situ; Disease-Free Survival; Feasi | 2001 |
Diagnostic efficacy of fluorescence cystoscopy for detection of urothelial neoplasms.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Female; Fluoresc | 2001 |
63 other studies available for aminolevulinic acid and Carcinoma, Intraepithelial
| Article | Year |
|---|---|
Efficacy and safety of photodynamic therapy mediatied by 5-aminolevulinic acid for the treatment of vaginal high-grade intraepithelial lesions.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Female; Humans; Papillomaviridae; Papillomavirus Infections; | 2022 |
Comparative study of topical 5-aminolevulinic acid photodynamic therapy (5-ALA-PDT) and surgery for the treatment of high-grade vaginal intraepithelial neoplasia.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Female; Humans; Middle Aged; Papillomavirus Infections; Phot | 2022 |
5-aminolevulinic acid photodynamic therapy combined with carbon dioxide laser therapy is a safe and effective treatment for vaginal intraepithelial neoplasia.
Topics: Aminolevulinic Acid; Carbon Dioxide; Carcinoma in Situ; Female; Humans; Laser Therapy; Lasers, Gas; | 2023 |
Er: YAG laser assisted photodynamic therapy for the management of severe oral epithelial dysplasia with innate and adaptive immune responses.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Humans; Immunity; Laser Therapy; Lasers, Solid-State; Photoc | 2023 |
Efficacy of a New Therapeutic Option for Vulvar Intraepithelial Neoplasia: Superficial Shaving Combined With Photodynamic Therapy.
Topics: Adult; Aminolevulinic Acid; Carcinoma in Situ; Female; Humans; Middle Aged; Patient Satisfaction; Ph | 2020 |
Photodynamic therapy for cutaneous squamous cell carcinoma in situ: Impact of anatomic location, tumor diameter, and incubation time on effectiveness.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Analysis of Variance; Biopsy, Needle; Carcinoma in Sit | 2020 |
5-aminolevulinic acid-mediated photodynamic diagnosis using fluorescence ureterorenoscopy for urinary upper tract urothelial carcinoma ∼Preliminary prospective single centre trial∼.
Topics: Administration, Oral; Aged; Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Female; Fluorescence | 2020 |
A case of carcinoma in situ of the lower lip successfully treated with shaving and photodynamic therapy.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Humans; Lip; Photochemotherapy; Photosensitizing Agents | 2021 |
The diagnostic challenge of suspicious or positive malignant urine cytology findings when cystoscopy findings are normal: an outpatient blue-light flexible cystoscopy may solve the problem.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell; Cystoscopy; Humans; Outpatient | 2021 |
Laser photodynamic treatment for in situ squamous cell carcinoma of the glans monitored by reflectance confocal microscopy.
Topics: Aged; Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Squamous Cell; Humans; Laser Therapy; Male; | 2014 |
Can photodynamic therapy be the preferred treatment option for anal intraepithelial neoplasia? Initial results of a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Anus Neoplasms; Carcinoma in Situ; Dihematoporp | 2014 |
Safe ablation of the anal mucosa and perianal skin in rats using Photodynamic Therapy--a promising approach for treating Anal Intraepithelial Neoplasia.
Topics: Aminolevulinic Acid; Animals; Anus Neoplasms; Carcinoma in Situ; Female; Intestinal Mucosa; Photoche | 2013 |
Diagnostic approach for cancer cells in urine sediments by 5-aminolevulinic acid-based photodynamic detection in bladder cancer.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Cell Line, Tumor; Cytologica | 2014 |
Reducing understaging of bladder cancer with the aid of photodynamic cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Female; Fluoresc | 2016 |
Optimised photodynamic diagnosis for transurethral resection of the bladder (TURB) in German clinical practice: results of the noninterventional study OPTIC III.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell; Cysto | 2017 |
Diagnostic Accuracy of Hexaminolevulinate in a Cohort of Patients Undergoing Radical Cystectomy.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell | 2017 |
[Photodynamic therapy in vulvar intraepithelial neoplasia].
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Dis | 2008 |
Hexylaminolaevulinate 'blue light' fluorescence cystoscopy in the investigation of clinically unconfirmed positive urine cytology.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell | 2009 |
Photodynamic therapy for the treatment of in situ squamous cell carcinoma of the left eyelid.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Squamous Cell; Eyelid Neoplasms; Humans; Male; Mi | 2008 |
Cytogenetic analysis of false-positive mucosa by photodynamic diagnosis using 5-aminolevulinic acid - possible existence of premalignant genomic alterations examined by in vitro experiment.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Chromosome Aberrations; Cytogenetic | 2009 |
Editorial comment on: A new generation of optical diagnostics for bladder cancer: technology, diagnostic accuracy, and future applications.
Topics: Aminolevulinic Acid; Carbon Radioisotopes; Carcinoma in Situ; Diagnostic Techniques, Urological; For | 2009 |
Improved detection and reduced early recurrence of non-muscle-invasive bladder cancer using hexaminolaevulinate fluorescence cystoscopy: results of a multicentre prospective randomized study (PC B305).
Topics: Aminolevulinic Acid; Carcinoma in Situ; Clinical Trials, Phase III as Topic; Cystoscopy; Humans; Mic | 2009 |
Long-term follow-up of in situ extramammary Paget's disease in Asian skin types IV/V treated with photodynamic therapy.
Topics: Administration, Cutaneous; Aged; Aged, 80 and over; Aminolevulinic Acid; Asian People; Carcinoma in | 2010 |
Photodynamic diagnosis in patients with T1G3 bladder cancer: influence on recurrence rate.
Topics: Aged; Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Female; Follow-Up Studies; Humans; Kaplan- | 2010 |
Topical photodynamic therapy is very effective for oral verrucous hyperplasia and oral erythroleukoplakia.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma in Situ; Erythroplasia; Femal | 2010 |
Photodynamic therapy of vulvar intraepithelial neoplasia using methyl aminolevulinate.
Topics: Adult; Aminolevulinic Acid; Carcinoma in Situ; Female; Humans; Photochemotherapy; Photosensitizing A | 2012 |
Blue light cystoscopy for detection and treatment of non-muscle invasive bladder cancer.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Fluorescence; Humans; Patient Selection; Urinary | 2012 |
Could basic research shed light on false positivity in photodynamic diagnosis?
Topics: Aminolevulinic Acid; Carcinoma in Situ; Diagnostic Techniques, Urological; False Positive Reactions; | 2012 |
[Fluorescence cystoscopy in bladder cancer: what future?].
Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell; Cystoscopy; Diagnosis, Differe | 2002 |
Role of 5-aminolevulinic acid in the detection of urothelial premalignant lesions.
Topics: Aminolevulinic Acid; Biomarkers, Tumor; Biopsy; Carcinoma in Situ; Carcinoma, Transitional Cell; End | 2002 |
Do patients profit from 5-aminolevulinic acid-induced fluorescence diagnosis in transurethral resection of bladder carcinoma?
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma in Situ; Fluorescence; Humans | 2002 |
Fluorescence confocal microscopy and image analysis of bladder cancer using 5-aminolevulinic acid.
Topics: Administration, Intravesical; Aminolevulinic Acid; Biomarkers, Tumor; Carcinoma in Situ; Carcinoma, | 2003 |
Fluorescence cytology of the urinary bladder.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Trans | 2003 |
Endoscopic fluorescence detection of intraepithelial neoplasia in Barrett's esophagus after oral administration of aminolevulinic acid.
Topics: Administration, Oral; Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Carcinoma in Situ; Esopha | 2003 |
Treatment of grade III anal intraepithelial neoplasia with photodynamic therapy: report of a case.
Topics: Aminolevulinic Acid; Anus Neoplasms; Carcinoma in Situ; Female; Humans; Middle Aged; Neoplasm Stagin | 2003 |
Improved detection of urothelial carcinoma in situ with hexaminolevulinate fluorescence cystoscopy.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Female; Fluoresc | 2004 |
[Photodynamic diagnosis of vulvar precancerous conditions and invasive cancers using 5-aminolevulinic acid].
Topics: Aminolevulinic Acid; Carcinoma in Situ; Diagnostic Techniques, Obstetrical and Gynecological; Female | 2003 |
Hexaminolevulinate-induced fluorescence endoscopy in patients with rectal adenoma and cancer: a pilot study.
Topics: Adenoma; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma in Situ; Cell Transformatio | 2004 |
Treatment of grade III anal intraepithelial neoplasia with photodynamic therapy: report of a case. Dis Colon Rectum, 2003; 46(11):1555-1559.
Topics: Aminolevulinic Acid; Anus Neoplasms; Carcinoma in Situ; Female; Humans; Middle Aged; Neoplasm Stagin | 2004 |
Evaluation of different treatment modalities for vulvar intraepithelial neoplasia (VIN): CO(2) laser vaporization, photodynamic therapy, excision and vulvectomy.
Topics: Adult; Aminolevulinic Acid; Carcinoma in Situ; Female; Gynecologic Surgical Procedures; Humans; Lase | 2006 |
Design and evaluation of a water-soluble bioadhesive patch formulation for cutaneous delivery of 5-aminolevulinic acid to superficial neoplastic lesions.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Carcinoma in Situ; Drug Delivery Systems; F | 2006 |
Hexyl aminolevulinate in the detection of bladder cancer: profile report.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Clinical Trials as Topic; Cystoscopy; Humans; Male; Photosen | 2006 |
[Fluorescence cytology of the urinary bladder after instillation of 5-aminolevulinic acid].
Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell; Cell Division; Humans; Microsc | 2007 |
Detection of early bladder cancer by 5-aminolevulinic acid induced porphyrin fluorescence.
Topics: Administration, Intravesical; Aged; Aminolevulinic Acid; Biopsy; Carcinoma in Situ; Carcinoma, Trans | 1996 |
Photodynamic therapy of nonmelanoma skin cancer with topical aminolevulinic acid: a clinical and histologic study.
Topics: Administration, Cutaneous; Aged; Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Basal Cell; Carc | 1995 |
[Photodynamic diagnosis of urothelial neoplasms after intravesicular instillation of 5-aminolevulinic acid].
Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma | 1994 |
Intravesical instillation of 5-aminolevulinic acid: the fluorescent metabolite is limited to urothelial cells.
Topics: Administration, Intravesical; Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Papillary; Cell Lin | 1994 |
[The clinical value of fluorescence cystoscopy in the detection of superficial transitional epithelial cell carcinoma of the bladder].
Topics: Administration, Intravesical; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Carci | 1997 |
Photodynamic treatment for lower genital tract intraepithelial neoplasia.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Female; Humans; Photochemotherapy; Photosensitizing Agents; | 1998 |
Fluorescence detection of flat transitional cell carcinoma after intravesical instillation of aminolevulinic acid.
Topics: Administration, Intravesical; Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Papillary; Cystosco | 1998 |
Fluorescence cystoscopy in the diagnostics and treatment of bladder tumors.
Topics: Aminolevulinic Acid; Biopsy; Carcinoma in Situ; Carcinoma, Transitional Cell; Cystoscopes; Endoscope | 1998 |
Clinical results of the transurethreal resection and evaluation of superficial bladder carcinomas by means of fluorescence diagnosis after intravesical instillation of 5-aminolevulinic acid.
Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma | 1999 |
Erythroplasia of Queyrat treated by topical aminolaevulinic acid photodynamic therapy.
Topics: Administration, Topical; Aged; Aminolevulinic Acid; Carcinoma in Situ; Erythroplasia; Humans; Male; | 1999 |
Single-episode photodynamic therapy and vulval intraepithelial neoplasia type III resistant to conventional therapy.
Topics: Adult; Aminolevulinic Acid; Carcinoma in Situ; Female; Humans; Photochemotherapy; Photosensitizing A | 2000 |
Photodynamic therapy for in situ squamous cell carcinoma on chronic radiation dermatitis after photosensitization with 5-aminolaevulinic acid.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Squamous Cell; Fingers; Humans; Male; Middle Aged | 2000 |
Role of 5-aminolevulinic acid in the diagnosis and treatment of superficial bladder cancer: improvement in diagnostic sensitivity.
Topics: Adult; Aged; Aminolevulinic Acid; Carcinoma in Situ; Cystoscopy; Female; Fluorescence; Humans; Male; | 2001 |
Fluorescence staining of oral cancer using a topical application of 5-aminolevulinic acid: fluorescence microscopic studies.
Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Squamous Cell; Fluorescence; Humans; Microscopy, | 2001 |
[Fluorescence cytology of the urinary bladder].
Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell; Cystoscopy; Humans; Microscopy | 2001 |
Photodynamic effects induced by aminolevulinic acid esters on human cervical carcinoma cells in culture.
Topics: Aminolevulinic Acid; Annexin A5; Apoptosis; Carcinoma in Situ; Cell Membrane; Cell Survival; Dose-Re | 2001 |
Significance of fluorescence cystoscopy for diagnosis of superficial bladder cancer after intravesical instillation of delta aminolevulinic acid.
Topics: Adenocarcinoma; Administration, Intravesical; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; | 2001 |
Occurrence of chromosome 9 and p53 alterations in multifocal dysplasia and carcinoma in situ of human urinary bladder.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma in Situ; Chromosome Aberrations; Chromosomes | 2002 |
New aspect of photodynamic diagnosis of bladder tumors: fluorescence cytology.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Anthracenes; Carcinoma in Situ; Cystitis; Cytophotomet | 2002 |
[Fluorescent endoscopy superior to white light endoscopy. Detecting cancers of the urinary bladder earlier].
Topics: Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Transitional Cell; Cystoscopy; Fluorescence; Huma | 2002 |