aminolevulinic acid has been researched along with Carcinoma, Anaplastic in 37 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We determined and evaluated the effect of photodynamic therapy (PDT) using topical 5-aminolevulinic acid (ALA) cream in treating human undifferentiated thyroid carcinoma (UTC)-bearing nude mice." | 7.73 | Photodynamic therapy of human undifferentiated thyroid carcinoma-bearing nude mice using topical 5-aminolevulinic acid. ( Al-Watban, FA; Zhang, XY, 2005) |
| "The purpose of this study was to investigate the potential use of 5-aminolevulinic acid (5-ALA, 5-amino-4-oxovaleric acid) induced protoporphyrin IX (PPIX) for photodynamic therapy (PDT) of nasopharyngeal carcinoma (NPC) and its related mechanisms of inducing cell death." | 7.71 | In vitro photodynamic therapy of nasopharyngeal carcinoma using 5-aminolevulinic acid. ( Baumgartner, R; Betz, CS; Heinrich, P; Janda, P; Lai, JP; Leunig, A; Stepp, H; Xiang, W, 2002) |
| "UTC constitutes almost 10% of thyroid cancers and shows a very poor response to chemotherapy." | 5.33 | Photodynamic therapy of human undifferentiated thyroid carcinoma-bearing nude mice using topical 5-aminolevulinic acid. ( Al-Watban, FA; Zhang, XY, 2005) |
| "Hexyl aminolevulinate, the hexyl ester of 5-aminolevulinic acid, is a photosensitising agent designed to enhance the detection of bladder cancer tumours, in particular highly malignant carcinoma in situ (CIS)." | 4.83 | Hexyl aminolevulinate: in the detection of bladder cancer. ( Frampton, JE; Plosker, GL, 2006) |
| " The use of paclitaxel is under clinical investigation; it shows about a 50% response rate, but it is not able to alter the fatal outcome for patients with anaplastic carcinoma." | 3.74 | High energy shock waves activate 5'-aminolevulinic Acid and increase permeability to Paclitaxel: antitumor effects of a new combined treatment on anaplastic thyroid cancer cells. ( Berta, L; Boccuzzi, G; Bosco, O; Catalano, MG; Costantino, L; Fortunati, N; Frairia, R; Pugliese, M, 2007) |
| "Laryngeal lesions (N = 39; 21 after administration of delta-aminolevulinic acid (ALA)) were investigated with laser-induced fluorescence, and the results correlated to histopathologic grading in 4 groups: non/mild dysplasia (I), moderate dysplasia (II), severe dysplasia/cancer in situ (III), and carcinoma." | 3.74 | Fluorescence investigations to classify malignant laryngeal lesions in vivo. ( Andersson-Engels, S; Eker, C; Krogdahl, A; Rydell, R; Svanberg, K; Wahlberg, P, 2008) |
| "We determined and evaluated the effect of photodynamic therapy (PDT) using topical 5-aminolevulinic acid (ALA) cream in treating human undifferentiated thyroid carcinoma (UTC)-bearing nude mice." | 3.73 | Photodynamic therapy of human undifferentiated thyroid carcinoma-bearing nude mice using topical 5-aminolevulinic acid. ( Al-Watban, FA; Zhang, XY, 2005) |
| "The purpose of this study was to investigate the potential use of 5-aminolevulinic acid (5-ALA, 5-amino-4-oxovaleric acid) induced protoporphyrin IX (PPIX) for photodynamic therapy (PDT) of nasopharyngeal carcinoma (NPC) and its related mechanisms of inducing cell death." | 3.71 | In vitro photodynamic therapy of nasopharyngeal carcinoma using 5-aminolevulinic acid. ( Baumgartner, R; Betz, CS; Heinrich, P; Janda, P; Lai, JP; Leunig, A; Stepp, H; Xiang, W, 2002) |
| "Eleven patients with high-grade mucosal dysplasia in a columnar-lined oesophagus and 2 patients with a squamous carcinoma (uT1) underwent photodynamic therapy (PDT) and argon-plasma coagulation (APC)." | 3.70 | [Photodynamic ablation and argon-plasma coagulation of premalignant and early-stage malignant lesions of the oesophagus--an alternative to surgery?]. ( Beger, HG; Orth, K; Rück, A; Russ, D; Stanescu, A, 1999) |
| "The drugs used in the treatment of bladder cancer are represented by the products referred to diagnosis (hexyl aminolevulinate), the intravesical instillations for the treatment of tumors not infiltrating the muscle and the infiltrating tumor chemotherapy (neo-adjuvant treatment or metastatic tumors)." | 2.49 | [Medical treatment of bladder carcinoma]. ( Bastide, C; Bay, JO; Bruyere, F; Guy, L; Karsenty, G; Mahammedi, H, 2013) |
| "The mean number of metastases detected by the PDD was significantly higher than that of white light for FT821 (p=0." | 1.37 | 5-Aminolevulinic acid-induced fluorescence diagnosis of pleural malignant tumor. ( Ali, AH; Kakiuchi, S; Kenzaki, K; Kondo, K; Matsuoka, H; Nakagawa, Y; Sakiyama, S; Sekido, Y; Sone, S; Takizawa, H; Tangoku, A; Toba, H, 2011) |
| "UTC constitutes almost 10% of thyroid cancers and shows a very poor response to chemotherapy." | 1.33 | Photodynamic therapy of human undifferentiated thyroid carcinoma-bearing nude mice using topical 5-aminolevulinic acid. ( Al-Watban, FA; Zhang, XY, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (10.81) | 18.2507 |
| 2000's | 13 (35.14) | 29.6817 |
| 2010's | 14 (37.84) | 24.3611 |
| 2020's | 6 (16.22) | 2.80 |
| Authors | Studies |
|---|---|
| Eskiler, GG | 1 |
| Turna, O | 1 |
| Ozkan, AD | 1 |
| Baykal, A | 1 |
| Gurgen, HO | 1 |
| Erk, B | 1 |
| Armutak, EI | 1 |
| Lim, HS | 1 |
| Hoogeveen, F | 1 |
| Blanker, MH | 1 |
| Cauberg, E | 1 |
| Steffens, MG | 1 |
| Bernad, I | 1 |
| Aguado, L | 1 |
| Núñez-Córdoba, JM | 1 |
| Redondo, P | 1 |
| Zduniak, K | 1 |
| Gdesz-Birula, K | 1 |
| Woźniak, M | 1 |
| Duś-Szachniewicz, K | 1 |
| Ziółkowski, P | 1 |
| Todenhöfer, T | 1 |
| Maas, M | 1 |
| Ketz, M | 1 |
| Kossack, N | 1 |
| Colling, C | 1 |
| Qvick, B | 1 |
| Stenzl, A | 3 |
| Gierth, M | 1 |
| Breyer, J | 1 |
| Zeman, F | 1 |
| Fritsche, HM | 1 |
| Cordes, J | 1 |
| Karl, A | 1 |
| Zaak, D | 1 |
| von Schmeling, IK | 1 |
| Sommerhuber, A | 1 |
| Zierer, T | 1 |
| Burger, M | 2 |
| Mayr, R | 1 |
| Papanikolaou, M | 1 |
| Tsianou, Z | 1 |
| Skellett, AM | 1 |
| Murphy, J | 1 |
| Millington, GWM | 1 |
| Guy, L | 1 |
| Mahammedi, H | 1 |
| Bastide, C | 1 |
| Bruyere, F | 1 |
| Karsenty, G | 1 |
| Bay, JO | 1 |
| Terada, Y | 1 |
| Inoue, K | 2 |
| Matsumoto, T | 1 |
| Ishihara, M | 1 |
| Hamada, K | 1 |
| Shimamura, Y | 1 |
| Ogata, K | 1 |
| Taniguchi, Y | 1 |
| Horino, T | 1 |
| Karashima, T | 1 |
| Tamura, K | 1 |
| Fukuhara, H | 1 |
| Fujimoto, S | 1 |
| Tsuda, M | 1 |
| Shuin, T | 1 |
| Lerner, SP | 1 |
| Goh, A | 1 |
| Lane, GI | 1 |
| Downs, TM | 1 |
| Soubra, A | 1 |
| Rao, A | 1 |
| Hemsley, L | 1 |
| Laylan, C | 1 |
| Shi, F | 1 |
| Konety, B | 1 |
| Alvarez, MG | 1 |
| Milanesio, M | 1 |
| Rivarola, V | 1 |
| Durantini, E | 1 |
| Batlle, A | 1 |
| Fukuda, H | 1 |
| Xie, Y | 1 |
| Wei, ZB | 1 |
| Zhang, Z | 1 |
| Wen, W | 1 |
| Huang, GW | 1 |
| Engh, JA | 1 |
| Fasanmade, A | 1 |
| Milne, J | 1 |
| Taylor, D | 1 |
| Godden, D | 1 |
| Penkoff, H | 1 |
| Dajc-Sommerer, E | 1 |
| Zumbraegel, A | 1 |
| Hoeltl, L | 1 |
| Scholz, M | 1 |
| Riedl, C | 1 |
| Bugelnig, J | 1 |
| Hobisch, A | 1 |
| Mikuz, G | 1 |
| Pichlmeier, U | 1 |
| Ali, AH | 1 |
| Takizawa, H | 1 |
| Kondo, K | 1 |
| Matsuoka, H | 1 |
| Toba, H | 1 |
| Nakagawa, Y | 1 |
| Kenzaki, K | 1 |
| Sakiyama, S | 1 |
| Kakiuchi, S | 1 |
| Sekido, Y | 1 |
| Sone, S | 1 |
| Tangoku, A | 1 |
| Ewelt, C | 1 |
| Floeth, FW | 1 |
| Felsberg, J | 2 |
| Steiger, HJ | 2 |
| Sabel, M | 2 |
| Langen, KJ | 1 |
| Stoffels, G | 1 |
| Stummer, W | 1 |
| Kamp, MA | 1 |
| Grosser, P | 1 |
| Slotty, PJ | 1 |
| Reifenberger, G | 1 |
| van der Beek, N | 1 |
| de Leeuw, J | 1 |
| Demmendal, C | 1 |
| Bjerring, P | 1 |
| Neumann, HA | 1 |
| Kriz, M | 1 |
| Hegyi, J | 1 |
| Ruzicka, T | 1 |
| Berking, C | 1 |
| Gravas, S | 1 |
| Efstathiou, K | 1 |
| Zachos, I | 1 |
| Melekos, MD | 1 |
| Tzortzis, V | 1 |
| Manivasager, V | 2 |
| Heng, PW | 2 |
| Hao, J | 1 |
| Zheng, W | 1 |
| Soo, KC | 2 |
| Olivo, M | 2 |
| Betz, CS | 1 |
| Lai, JP | 1 |
| Xiang, W | 1 |
| Janda, P | 1 |
| Heinrich, P | 1 |
| Stepp, H | 1 |
| Baumgartner, R | 2 |
| Leunig, A | 1 |
| Bogaards, A | 1 |
| Varma, A | 1 |
| Zhang, K | 1 |
| Zach, D | 1 |
| Bisland, SK | 1 |
| Moriyama, EH | 1 |
| Lilge, L | 1 |
| Muller, PJ | 1 |
| Wilson, BC | 1 |
| Al-Watban, FA | 1 |
| Zhang, XY | 1 |
| Wu, RW | 1 |
| Chu, ES | 1 |
| Yow, CM | 1 |
| Chen, JY | 1 |
| Shahzidi, S | 1 |
| Stokke, T | 1 |
| Soltani, H | 1 |
| Nesland, JM | 1 |
| Peng, Q | 1 |
| Frampton, JE | 1 |
| Plosker, GL | 1 |
| Yee, KK | 1 |
| Catalano, MG | 1 |
| Costantino, L | 1 |
| Fortunati, N | 1 |
| Bosco, O | 1 |
| Pugliese, M | 1 |
| Boccuzzi, G | 1 |
| Berta, L | 1 |
| Frairia, R | 1 |
| Rydell, R | 1 |
| Eker, C | 1 |
| Andersson-Engels, S | 1 |
| Krogdahl, A | 1 |
| Wahlberg, P | 1 |
| Svanberg, K | 1 |
| Kriegmair, M | 1 |
| Riesenberg, R | 1 |
| Jocham, D | 1 |
| Sassy, T | 1 |
| Stocker, S | 1 |
| Lumper, W | 1 |
| Unsöld, E | 1 |
| Hofstetter, A | 1 |
| Messmann, H | 1 |
| Geisler, M | 1 |
| Gross, U | 1 |
| Abels, C | 1 |
| Szeimies, RM | 1 |
| Steinbach, P | 1 |
| Knüchel, R | 1 |
| Doss, M | 1 |
| Schölmerich, J | 1 |
| Holstege, A | 1 |
| Revenga Arranz, F | 1 |
| Orth, K | 1 |
| Stanescu, A | 1 |
| Rück, A | 1 |
| Russ, D | 1 |
| Beger, HG | 1 |
| Tunstall, RG | 1 |
| Barnett, AA | 1 |
| Schofield, J | 1 |
| Griffiths, J | 1 |
| Vernon, DI | 1 |
| Brown, SB | 1 |
| Roberts, DJ | 1 |
4 reviews available for aminolevulinic acid and Carcinoma, Anaplastic
| Article | Year |
|---|---|
[Medical treatment of bladder carcinoma].
Topics: Aminolevulinic Acid; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; BC | 2013 |
Novel endoscopic diagnosis for bladder cancer.
Topics: Aminolevulinic Acid; Carcinoma; Carcinoma, Papillary; Clinical Trials, Phase III as Topic; Cystoscop | 2015 |
Hexyl aminolevulinate: in the detection of bladder cancer.
Topics: Aminolevulinic Acid; Animals; Carcinoma; Cystoscopy; Humans; Photosensitizing Agents; Urinary Bladde | 2006 |
[Medical treatment of epitheliomas].
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Antineoplastic Agents; Bowen's Disease; Carcinoma; Car | 1997 |
4 trials available for aminolevulinic acid and Carcinoma, Anaplastic
| Article | Year |
|---|---|
Daylight photodynamic therapy for prevention of new actinic keratosis and keratinocyte carcinomas in organ transplants. A cryotherapy-controlled randomized clinical trial.
Topics: Aged; Aminolevulinic Acid; Carcinoma; Cryotherapy; Humans; Keratinocytes; Keratosis, Actinic; Male; | 2020 |
The HELENA study: Hexvix
Topics: Administration, Intravesical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Antineoplastic Ag | 2021 |
Detection and clinical outcome of urinary bladder cancer with 5-aminolevulinic acid-induced fluorescence cystoscopy : A multicenter randomized, double-blind, placebo-controlled trial.
Topics: Administration, Intravesical; Aged; Algorithms; Aminolevulinic Acid; Carcinoma; Cystoscopy; Disease- | 2011 |
PpIX fluorescence combined with auto-fluorescence is more accurate than PpIX fluorescence alone in fluorescence detection of non-melanoma skin cancer: an intra-patient direct comparison study.
Topics: Aminolevulinic Acid; Biomarkers, Tumor; Bowen's Disease; Carcinoma; Carcinoma, Basal Cell; False Neg | 2012 |
29 other studies available for aminolevulinic acid and Carcinoma, Anaplastic
| Article | Year |
|---|---|
The response of the canine mammary simple carcinoma and carcinosarcoma cells to 5-aminolaevulinic acid-based photodynamic therapy: An in vitro study.
Topics: Aminolevulinic Acid; Animals; Apoptosis; Carcinoma; Carcinosarcoma; Cell Line, Tumor; Dogs; Humans; | 2022 |
Recurrence of non-muscle invasive bladder carcinoma after transurethral resection with hexaminolevulinate photodynamic diagnosis or regular cystoscopy.
Topics: Aminolevulinic Acid; Carcinoma; Cystoscopy; Humans; Neoplasm Recurrence, Local; Retrospective Studie | 2023 |
The Assessment of the Combined Treatment of 5-ALA Mediated Photodynamic Therapy and Thalidomide on 4T1 Breast Carcinoma and 2H11 Endothelial Cell Line.
Topics: Aminolevulinic Acid; Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Cell Line, Tumor; Endothe | 2020 |
Retrospective German claims data study on initial treatment of bladder carcinoma (BCa) by transurethral bladder resection (TURB): a comparative analysis of costs using standard white light- (WL-) vs. blue light- (BL-) TURB.
Topics: Aged; Aminolevulinic Acid; Carcinoma; Cystectomy; Cystoscopy; Female; Germany; Health Care Costs; He | 2021 |
Radiotherapy-induced morphoea of the breast responding to photodynamic therapy.
Topics: Aged; Aminolevulinic Acid; Breast Neoplasms; Carcinoma; Female; Humans; Photochemotherapy; Photosens | 2018 |
5-Aminolevulinic acid protects against cisplatin-induced nephrotoxicity without compromising the anticancer efficiency of cisplatin in rats in vitro and in vivo.
Topics: Acute Kidney Injury; Aminolevulinic Acid; Animals; Antineoplastic Agents; Apoptosis; Carcinoma; Casp | 2013 |
Tolerability of Repeat Use of Blue Light Cystoscopy with Hexaminolevulinate for Patients with Urothelial Cell Carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma; Cystoscopy; Female; Humans; Male; Mi | 2017 |
Endogenous and exogenous porphyrins as photosensitizers in the Hep-2 human carcinoma cell line.
Topics: Aminolevulinic Acid; Carcinoma; Cell Line, Tumor; Cell Survival; Fullerenes; Humans; Laryngeal Neopl | 2009 |
Effect of 5-ALA-PDT on VEGF and PCNA expression in human NPC-bearing nude mice.
Topics: Aminolevulinic Acid; Animals; Carcinoma; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; H | 2009 |
Improving intraoperative visualization of anaplastic foci within gliomas.
Topics: Aminolevulinic Acid; Biopsy; Brain Neoplasms; Carcinoma; Fluorescence; Glioma; Humans; Protoporphyri | 2010 |
Pre-surgical mapping of cutaneous non-melanoma carcinoma using topical methyl aminolevulinic acid.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Carcinoma; Carcinoma, Basal Cell; Carcinoma, Squamou | 2011 |
5-Aminolevulinic acid-induced fluorescence diagnosis of pleural malignant tumor.
Topics: Aminolevulinic Acid; Animals; Carcinoma; Cell Line, Tumor; Fluorescence; Humans; Lung Neoplasms; Mes | 2011 |
Finding the anaplastic focus in diffuse gliomas: the value of Gd-DTPA enhanced MRI, FET-PET, and intraoperative, ALA-derived tissue fluorescence.
Topics: Adult; Aminolevulinic Acid; Biopsy; Brain Neoplasms; Carcinoma; Contrast Media; Female; Fluorescence | 2011 |
5-aminolevulinic acid (5-ALA)-induced fluorescence in intracerebral metastases: a retrospective study.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Aminolevulinic Acid; Brain Neoplasms; Carcinoma; Female; Fl | 2012 |
Fluorescence diagnostics as a guide for demarcation and biopsy of suspected anal cancer.
Topics: Aged; Aminolevulinic Acid; Anus Neoplasms; Biopsy; Carcinoma; Eczema; Female; Fluorescence; Humans; | 2012 |
Is there a learning curve for photodynamic diagnosis of bladder cancer with hexaminolevulinate hydrochloride?
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma; Clinical Competence; Cystoscopy; False Posi | 2012 |
A study of 5-aminolevulinic acid and its methyl ester used in in vitro and in vivo systems of human bladder cancer.
Topics: Administration, Topical; Aminolevulinic Acid; Animals; Biological Transport, Active; Carcinoma; Cyst | 2003 |
In vitro photodynamic therapy of nasopharyngeal carcinoma using 5-aminolevulinic acid.
Topics: Aminolevulinic Acid; Apoptosis; Carcinoma; Cell Survival; Dose-Response Relationship, Drug; Drug Scr | 2002 |
Fluorescence image-guided brain tumour resection with adjuvant metronomic photodynamic therapy: pre-clinical model and technology development.
Topics: Aminolevulinic Acid; Animals; Apoptosis; Brain Neoplasms; Carcinoma; Diagnostic Imaging; Disease Mod | 2005 |
Photodynamic therapy of human undifferentiated thyroid carcinoma-bearing nude mice using topical 5-aminolevulinic acid.
Topics: Administration, Topical; Aminolevulinic Acid; Animals; Carcinoma; Humans; Mice; Mice, Nude; Neoplasm | 2005 |
Photodynamic effects on nasopharyngeal carcinoma (NPC) cells with 5-aminolevulinic acid or its hexyl ester.
Topics: Aminolevulinic Acid; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Dose-Response Relat | 2006 |
Induction of apoptosis by hexaminolevulinate-mediated photodynamic therapy in human colon carcinoma cell line 320DM.
Topics: Aminolevulinic Acid; Apoptosis; Carcinoma; Caspase 3; Caspase 9; Caspases; Cell Line, Tumor; Cell Su | 2006 |
A study comparing endogenous protoporphyrin IX induced by 5-ALA and ALA-methyl ester with exogenous PpIX and PpIX dimethyl ester in photodynamic diagnosis of human nasopharyngeal carcinoma xenografts.
Topics: Aminolevulinic Acid; Animals; Carcinoma; Humans; Male; Mice; Mice, Inbred Strains; Nasopharyngeal Ne | 2006 |
High energy shock waves activate 5'-aminolevulinic Acid and increase permeability to Paclitaxel: antitumor effects of a new combined treatment on anaplastic thyroid cancer cells.
Topics: Aminolevulinic Acid; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma; Cell Line, Tumor; Cell | 2007 |
Fluorescence investigations to classify malignant laryngeal lesions in vivo.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma; Female; Humans; Laryngeal Ne | 2008 |
Photodynamic diagnosis following topical application of delta-aminolevulinic acid in a rat bladder tumor model.
Topics: Administration, Intravesical; Aminolevulinic Acid; Animals; Butylhydroxybutylnitrosamine; Carcinoma; | 1994 |
Influence of a haematoporphyrin derivative on the protoporphyrin IX synthesis and photodynamic effect after 5-aminolaevulinic acid sensitization in human colon carcinoma cells.
Topics: Aminolevulinic Acid; Carcinoma; Colonic Neoplasms; Hematoporphyrins; Humans; Photochemotherapy; Phot | 1997 |
[Photodynamic ablation and argon-plasma coagulation of premalignant and early-stage malignant lesions of the oesophagus--an alternative to surgery?].
Topics: Aged; Aminolevulinic Acid; Argon; Barrett Esophagus; Carcinoma; Esophageal Neoplasms; Female; Humans | 1999 |
Porphyrin accumulation induced by 5-aminolaevulinic acid esters in tumour cells growing in vitro and in vivo.
Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Antineoplastic Agents; Carboxylesterase; Ca | 2002 |