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aminolevulinic acid and Cancer of Nasopharynx

aminolevulinic acid has been researched along with Cancer of Nasopharynx in 8 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to investigate the potential use of 5-aminolevulinic acid (5-ALA, 5-amino-4-oxovaleric acid) induced protoporphyrin IX (PPIX) for photodynamic therapy (PDT) of nasopharyngeal carcinoma (NPC) and its related mechanisms of inducing cell death."7.71In vitro photodynamic therapy of nasopharyngeal carcinoma using 5-aminolevulinic acid. ( Baumgartner, R; Betz, CS; Heinrich, P; Janda, P; Lai, JP; Leunig, A; Stepp, H; Xiang, W, 2002)
"The purpose of this study was to investigate the potential use of 5-aminolevulinic acid (5-ALA, 5-amino-4-oxovaleric acid) induced protoporphyrin IX (PPIX) for photodynamic therapy (PDT) of nasopharyngeal carcinoma (NPC) and its related mechanisms of inducing cell death."3.71In vitro photodynamic therapy of nasopharyngeal carcinoma using 5-aminolevulinic acid. ( Baumgartner, R; Betz, CS; Heinrich, P; Janda, P; Lai, JP; Leunig, A; Stepp, H; Xiang, W, 2002)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (87.50)29.6817
2010's0 (0.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Wu, RWK1
Chu, ESM1
Yow, CMN1
Xie, Y1
Wei, ZB1
Zhang, Z1
Wen, W1
Huang, GW1
Manivasager, V2
Heng, PW2
Hao, J1
Zheng, W1
Soo, KC2
Olivo, M2
Betz, CS1
Lai, JP1
Xiang, W1
Janda, P1
Heinrich, P1
Stepp, H1
Baumgartner, R1
Leunig, A1
Chu, ES2
Wu, RW2
Yow, CM2
Wong, TK1
Chen, JY2
Wang, CP1
Chang, YL1
Chen, CT1
Yang, TH1
Lou, PJ1
Yee, KK1

Other Studies

8 other studies available for aminolevulinic acid and Cancer of Nasopharynx

ArticleYear
Evaluation of the effect of 5-aminolevulinic acid hexyl ester (H-ALA) PDT on EBV LMP1 protein expression in human nasopharyngeal cells.
    Photodiagnosis and photodynamic therapy, 2020, Volume: 30

    Topics: Aminolevulinic Acid; Cell Line, Tumor; Cell Survival; Herpesvirus 4, Human; Humans; Lasers, Semicond

2020
Effect of 5-ALA-PDT on VEGF and PCNA expression in human NPC-bearing nude mice.
    Oncology reports, 2009, Volume: 22, Issue:6

    Topics: Aminolevulinic Acid; Animals; Carcinoma; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; H

2009
Macro-microscopic fluorescence imaging of human NPC xenografts in a murine model using topical vs intravenous administration of 5-aminolevulinic acid.
    International journal of oncology, 2002, Volume: 21, Issue:5

    Topics: Administration, Topical; Aminolevulinic Acid; Animals; Fluorescence; Humans; Injections, Intravenous

2002
In vitro photodynamic therapy of nasopharyngeal carcinoma using 5-aminolevulinic acid.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2002, Volume: 1, Issue:5

    Topics: Aminolevulinic Acid; Apoptosis; Carcinoma; Cell Survival; Dose-Response Relationship, Drug; Drug Scr

2002
The cytotoxic and genotoxic potential of 5-aminolevulinic acid on lymphocytes: a comet assay study.
    Cancer chemotherapy and pharmacology, 2006, Volume: 58, Issue:3

    Topics: Aged; Aminolevulinic Acid; Cell Line, Tumor; Cell Survival; Comet Assay; DNA Damage; Humans; Lymphoc

2006
Photodynamic effects on nasopharyngeal carcinoma (NPC) cells with 5-aminolevulinic acid or its hexyl ester.
    Cancer letters, 2006, Oct-08, Volume: 242, Issue:1

    Topics: Aminolevulinic Acid; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Dose-Response Relat

2006
Photodynamic therapy with topical 5-aminolevulinic acid as a post-operative adjuvant therapy for an incompletely resected primary nasopharyngeal papillary adenocarcinoma: a case report.
    Lasers in surgery and medicine, 2006, Volume: 38, Issue:5

    Topics: Adenocarcinoma, Papillary; Administration, Topical; Adult; Aminolevulinic Acid; Combined Modality Th

2006
A study comparing endogenous protoporphyrin IX induced by 5-ALA and ALA-methyl ester with exogenous PpIX and PpIX dimethyl ester in photodynamic diagnosis of human nasopharyngeal carcinoma xenografts.
    International journal of oncology, 2006, Volume: 29, Issue:4

    Topics: Aminolevulinic Acid; Animals; Carcinoma; Humans; Male; Mice; Mice, Inbred Strains; Nasopharyngeal Ne

2006