aminolevulinic acid has been researched along with Cancer of Liver in 37 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
| Excerpt | Reference |
|---|---|
| "The exact mechanism of carcinogenesis of this rare tumor is unknown, however." | ( Beykirch, MK; Bronisch, O; Haverkamp, T; Knösel, T; Mogler, C; Petrides, PE; Rummeny, C; Schmid, C; Stauch, T; Weichert, W, 2023) |
| "One patient had developed hepatocellular carcinoma (HCC), the other intrahepatic cholangiocarcinoma (CCA)." | ( Beykirch, MK; Bronisch, O; Haverkamp, T; Knösel, T; Mogler, C; Petrides, PE; Rummeny, C; Schmid, C; Stauch, T; Weichert, W, 2023) |
| "The acute hepatic porphyrias (AHP) are rare, inborn errors of heme-metabolism and include acute intermittent porphyria, hereditary coproporphyria, variegate porphyria, and porphyria due to severe deficiency of 5-aminolevulinic acid dehydratase." | ( Balwani, M; Bonkovsky, HL; Lim, JK; Wang, B, 2023) |
| "An increased incidence of hepatocellular carcinoma (HCC) has been reported as a long-term manifestation in symptomatic AIP patients." | ( Lichtenstein, F; Menezes, PR; Onuki, J; Pellegrina, DVDS; Reis, EM; Trufen, CEM, 2023) |
| "5-ALA fluorescence was detected in all hepatocellular carcinoma cases with serosa invasion." | ( Hayashi, M; Hirokawa, F; Inoue, Y; Komeda, K; Tanaka, R; Uchiyama, K, 2014) |
| "In liver metastasis from colorectal cancer cases with serosa invasion, 18 patients (85." | ( Hayashi, M; Hirokawa, F; Inoue, Y; Komeda, K; Tanaka, R; Uchiyama, K, 2014) |
| "Backgtound/Aim: Since hepatocellular carcinoma (HCC) has a high recurrence rate, accurate diagnosis of its location and curative resection is important to improve survival." | ( Fujiwara, H; Harada, K; Ichikawa, D; Ikoma, H; Kamada, Y; Morimura, R; Murayama, Y; Nishimura, M; Okamoto, K; Otsuji, E, 2016) |
| "We used two human hepatoma cell lines (HuH-7 and Hep G2)." | ( Fujiwara, H; Harada, K; Ichikawa, D; Ikoma, H; Kamada, Y; Morimura, R; Murayama, Y; Nishimura, M; Okamoto, K; Otsuji, E, 2016) |
| "Precise staging of gastric cancer is essential when selecting for the appropriate treatment approach." | ( Fujiwara, H; Harada, Y; Ichikawa, D; Ikoma, H; Koizumi, N; Kokuba, Y; Komatsu, S; Kubota, T; Kuriu, Y; Murayama, Y; Nakanishi, M; Ochiai, T; Okamoto, K; Otsuji, E; Shiozaki, A; Takamatsu, T, 2012) |
| "The main tumor and the satellite metastases clearly showed intense fluorescence compared with unaffected liver parenchyma and other abdominal organs." | ( Arnold, JC; Riemann, JF; Schneider, AR; Zöpf, T, 2002) |
| "In 15 patients with hepatocellular carcinoma (HCC) and 14 patients with liver cirrhosis (LC), urinary excretions of delta-aminolevulinic acid (ALA), porphobilinogen (PBG), uroporphyrin (UP), coproporphyrin (CP), and erythrocyte contents of CP and protoporphyrin (PP) were examined." | ( Hirayama, C; Horie, Y; Udagawa, M, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (5.41) | 18.7374 |
| 1990's | 5 (13.51) | 18.2507 |
| 2000's | 10 (27.03) | 29.6817 |
| 2010's | 13 (35.14) | 24.3611 |
| 2020's | 7 (18.92) | 2.80 |
| Authors | Studies |
|---|---|
| Haverkamp, T | 1 |
| Bronisch, O | 1 |
| Knösel, T | 1 |
| Mogler, C | 1 |
| Weichert, W | 1 |
| Stauch, T | 1 |
| Schmid, C | 1 |
| Rummeny, C | 1 |
| Beykirch, MK | 1 |
| Petrides, PE | 1 |
| Wang, B | 1 |
| Bonkovsky, HL | 1 |
| Lim, JK | 1 |
| Balwani, M | 1 |
| Menezes, PR | 2 |
| Trufen, CEM | 1 |
| Lichtenstein, F | 1 |
| Pellegrina, DVDS | 1 |
| Reis, EM | 1 |
| Onuki, J | 4 |
| Kumar, A | 1 |
| Pecquenard, F | 1 |
| Baydoun, M | 1 |
| Quilbé, A | 1 |
| Moralès, O | 1 |
| Leroux, B | 1 |
| Aoudjehane, L | 1 |
| Conti, F | 1 |
| Boleslawski, E | 1 |
| Delhem, N | 1 |
| Shi, Y | 1 |
| Hu, F | 1 |
| Fu, H | 1 |
| Li, S | 1 |
| Lu, C | 1 |
| Hu, C | 1 |
| Lissing, M | 1 |
| Wester, A | 1 |
| Vassiliou, D | 1 |
| Floderus, Y | 1 |
| Harper, P | 1 |
| Sardh, E | 1 |
| Wahlin, S | 1 |
| Ozten, O | 1 |
| Guney Eskiler, G | 1 |
| Sonmez, F | 1 |
| Yıldız, MZ | 1 |
| Borgia, F | 1 |
| Saitta, C | 1 |
| Vaccaro, M | 1 |
| Franzè, MS | 1 |
| Lentini, M | 1 |
| Cannavò, SP | 1 |
| Abo-Zeid, MAM | 1 |
| Abo-Elfadl, MT | 1 |
| Mostafa, SM | 1 |
| Nakano, T | 1 |
| Moriya, K | 1 |
| Koike, K | 1 |
| Horie, T | 1 |
| González, CB | 1 |
| DeSouza, AO | 1 |
| Maria, DA | 1 |
| Maitra, D | 1 |
| Carter, EL | 1 |
| Richardson, R | 1 |
| Rittié, L | 1 |
| Basrur, V | 1 |
| Zhang, H | 1 |
| Nesvizhskii, AI | 1 |
| Osawa, Y | 1 |
| Wolf, MW | 1 |
| Ragsdale, SW | 1 |
| Lehnert, N | 1 |
| Herrmann, H | 1 |
| Omary, MB | 1 |
| Inoue, Y | 2 |
| Tanaka, R | 1 |
| Komeda, K | 1 |
| Hirokawa, F | 2 |
| Hayashi, M | 2 |
| Uchiyama, K | 2 |
| Laafi, J | 1 |
| Homedan, C | 1 |
| Jacques, C | 1 |
| Gueguen, N | 1 |
| Schmitt, C | 1 |
| Puy, H | 1 |
| Reynier, P | 1 |
| Carmen Martinez, M | 1 |
| Malthièry, Y | 1 |
| Kaibori, M | 1 |
| Matsui, K | 1 |
| Ishizaki, M | 1 |
| Iida, H | 1 |
| Okumura, T | 1 |
| Sakaguchi, T | 1 |
| Inoue, K | 1 |
| Ikeura, T | 1 |
| Asano, H | 1 |
| Kon, M | 1 |
| Nishimura, M | 1 |
| Murayama, Y | 2 |
| Harada, K | 1 |
| Kamada, Y | 1 |
| Morimura, R | 1 |
| Ikoma, H | 2 |
| Ichikawa, D | 2 |
| Fujiwara, H | 2 |
| Okamoto, K | 2 |
| Otsuji, E | 2 |
| Imai, Y | 1 |
| Fujii, K | 1 |
| Kishi, K | 1 |
| Fujiwara, Y | 1 |
| Yano, M | 1 |
| Inoue, M | 1 |
| Miyashiro, I | 1 |
| Motoori, M | 1 |
| Shingai, T | 1 |
| Gotoh, K | 1 |
| Takahashi, H | 1 |
| Noura, S | 1 |
| Yamada, T | 1 |
| Ohue, M | 1 |
| Ohigashi, H | 1 |
| Ishikawa, O | 1 |
| Koizumi, N | 1 |
| Komatsu, S | 1 |
| Shiozaki, A | 1 |
| Kuriu, Y | 1 |
| Kubota, T | 1 |
| Nakanishi, M | 1 |
| Harada, Y | 1 |
| Ochiai, T | 1 |
| Kokuba, Y | 1 |
| Takamatsu, T | 1 |
| Ren, QG | 1 |
| Wu, SM | 1 |
| Peng, Q | 1 |
| Chen, JY | 1 |
| Schneider, AR | 2 |
| Zöpf, T | 2 |
| Arnold, JC | 2 |
| Riemann, JF | 2 |
| Weickert, U | 1 |
| Till, H | 1 |
| Bergmann, F | 1 |
| Metzger, R | 1 |
| Haeberle, B | 1 |
| von Schweinitz, D | 1 |
| Prosst, R | 1 |
| Yow, CM | 1 |
| Wong, CK | 1 |
| Huang, Z | 1 |
| Ho, RJ | 1 |
| Alvarez, MG | 1 |
| Lacelli, MS | 1 |
| Rivarola, V | 1 |
| Batlle, A | 1 |
| Fukuda, H | 1 |
| Takeda, O | 1 |
| Takechi, S | 1 |
| Ito, S | 1 |
| Omori, H | 1 |
| Katoh, T | 1 |
| Yamaguchi, T | 1 |
| Morofuji, Y | 1 |
| Matsuo, T | 1 |
| Toyoda, K | 1 |
| Takeshita, T | 1 |
| Hirose, M | 1 |
| Hirao, T | 1 |
| Hayashi, Y | 1 |
| Tsutsumi, K | 1 |
| Abe, K | 1 |
| Nagata, I | 1 |
| Udagawa, M | 1 |
| Horie, Y | 1 |
| Hirayama, C | 1 |
| Egger, NG | 1 |
| Schoenecker, JA | 1 |
| Gourley, WK | 1 |
| Motamedi, M | 1 |
| Anderson, KE | 1 |
| Weinman, SA | 1 |
| Liu, DL | 1 |
| Svanberg, K | 1 |
| Wang, I | 1 |
| Andersson-Engels, S | 1 |
| Svanberg, S | 1 |
| Douki, T | 2 |
| Medeiros, MH | 2 |
| Bechara, EJ | 1 |
| Cadet, J | 2 |
| Di Mascio, P | 2 |
| De Siervi, A | 1 |
| Vazquez, ES | 1 |
| Rezaval, C | 1 |
| Rossetti, MV | 1 |
| del Batlle, AM | 1 |
| Teixeira, PC | 1 |
| Dörnemann, D | 1 |
| Fisch, RO | 1 |
| McCabe, ER | 1 |
| Doeden, D | 1 |
| Koep, LJ | 1 |
| Kohlhoff, JG | 1 |
| Silverman, A | 1 |
| Starzl, TE | 1 |
| Wainstok de Calmanovici, R | 1 |
| Cochón, AC | 1 |
| Zenklusen, JC | 1 |
| Aldonatti, C | 1 |
| Cabral, JR | 1 |
| San Martín de Viale, LC | 1 |
| Visser, O | 1 |
| van den Berg, JW | 1 |
| Koole-Lesuis, H | 1 |
| Voortman, G | 1 |
| Wilson, JH | 1 |
| Xie, R | 1 |
| Xu, T | 1 |
| Zhu, J | 1 |
| Wei, X | 1 |
| Zhu, W | 1 |
| Li, L | 1 |
| Wang, Y | 1 |
| Han, Y | 1 |
| Zhou, J | 1 |
| Bai, Y | 1 |
2 review(s) available for aminolevulinic acid and Cancer of Liver
| Article | Year |
|---|---|
Heterogeneous molecular behavior in liver tumors (HCC and CCA) of two patients with acute intermittent porphyria.
Topics: Adult; Aminolevulinic Acid; Carcinogenesis; Carcinoma, Hepatocellular; Female; Flavoproteins; Humans; Liver Neoplasms; Mitochondrial Proteins; Porphyria, Acute Intermittent; Porphyrins; Protoporphyrinogen Oxidase | 2023 |
AGA Clinical Practice Update on Diagnosis and Management of Acute Hepatic Porphyrias: Expert Review.
Topics: Abdominal Pain; Aminolevulinic Acid; Antiemetics; Carcinoma, Hepatocellular; Creatinine; Female; Heme; Hemin; Humans; Hypertension; Liver Neoplasms; Middle Aged; Porphobilinogen; Porphobilinogen Synthase; Porphyria, Acute Intermittent; Porphyrias, Hepatic; Quality of Life; Renal Insufficiency, Chronic; United States | 2023 |
35 other study(ies) available for aminolevulinic acid and Cancer of Liver
| Article | Year |
|---|---|
Transcriptome profile analysis reveals putative molecular mechanisms of 5-aminolevulinic acid toxicity.
Topics: Aminolevulinic Acid; Carcinogenesis; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Porphyria, Acute Intermittent; Reactive Oxygen Species; Transcriptome | 2023 |
An Efficient 5-Aminolevulinic Acid Photodynamic Therapy Treatment for Human Hepatocellular Carcinoma.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Culture Media, Conditioned; Humans; Liver Neoplasms; Liver Transplantation; Living Donors; Mice; Mice, SCID; Photochemotherapy; Photosensitizing Agents; Protoporphyrins | 2023 |
Low Dose of 5-Aminolevulinic Acid Hydrochloride Alleviates the Damage in Cardiomyocytes Induced by Lenvatinib via PI3K/AKT Signaling Pathway.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Hepatocellular; Liver Neoplasms; Mammals; Mice; Myocytes, Cardiac; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction | 2023 |
Porphyrin precursors and risk of primary liver cancer in acute intermittent porphyria: A case-control study of 188 patients.
Topics: Aged; Aminolevulinic Acid; Case-Control Studies; Humans; Liver Neoplasms; Middle Aged; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrins | 2023 |
Investigation of the therapeutic effect of 5-aminolevulinic acid based photodynamic therapy on hepatocellular carcinoma.
Topics: Aminolevulinic Acid; Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Liver Neoplasms; Photochemotherapy; Photosensitizing Agents; Protoporphyrins | 2022 |
Nodular-cystic eruption in course of sorafenib administration for hepatocarcinoma: An unconventional skin reaction requiring unconventional treatment.
Topics: Aminolevulinic Acid; Antineoplastic Agents; Carcinoma, Hepatocellular; Drug Eruptions; Humans; Liver Neoplasms; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Photochemotherapy; Photosensitizing Agents; Protein Kinase Inhibitors; Sorafenib | 2017 |
Photodynamic therapy using 5-aminolevulinic acid triggered DNA damage of adenocarcinoma breast cancer and hepatocellular carcinoma cell lines.
Topics: Adenocarcinoma; Aminolevulinic Acid; Breast Neoplasms; Carcinoma, Hepatocellular; DNA Damage; Hep G2 Cells; Humans; Liver Neoplasms; MCF-7 Cells; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Singlet Oxygen | 2018 |
Hepatitis C virus core protein triggers abnormal porphyrin metabolism in human hepatocellular carcinoma cells.
Topics: Aminolevulinic Acid; Biosynthetic Pathways; Carcinoma, Hepatocellular; Cells, Cultured; Hep G2 Cells; Hepacivirus; Hepatitis C; Humans; Liver Neoplasms; Porphyrins | 2018 |
Effect of 5-aminolevulinic acid on the expression of carcinogenesis-related proteins in cultured primary hepatocytes.
Topics: Aminolevulinic Acid; Animals; Apoptosis; Carcinogenesis; Carcinoma, Hepatocellular; Cell Proliferation; DNA Repair; Gene Expression Regulation; Hepatocytes; Lipid Metabolism; Liver; Liver Neoplasms; Male; Oxidative Stress; Primary Cell Culture; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase | 2018 |
Oxygen and Conformation Dependent Protein Oxidation and Aggregation by Porphyrins in Hepatocytes and Light-Exposed Cells.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Hepatocellular; Cell Line; Deferoxamine; Heme; Hepatocytes; Humans; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Oxygen; Photosensitivity Disorders; Photosensitizing Agents; Porphyrias; Porphyrins; Protein Aggregates; Protein Conformation; Protoporphyrins | 2019 |
Fluorescence detection of malignant liver tumors using 5-aminolevulinic acid-mediated photodynamic diagnosis: principles, technique, and clinical experience.
Topics: Aged; Aminolevulinic Acid; Anastomotic Leak; Carcinoma, Hepatocellular; Color; Colorectal Neoplasms; Female; Fluorescence; Hepatectomy; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm, Residual; Operative Time; Photosensitizing Agents; Protoporphyrins | 2014 |
Pro-oxidant effect of ALA is implicated in mitochondrial dysfunction of HepG2 cells.
Topics: Adenosine Triphosphate; Aminolevulinic Acid; Antioxidants; Blotting, Western; Carcinoma, Hepatocellular; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electron Transport Complex I; Gene Expression; Hep G2 Cells; Humans; Ion Channels; Liver Neoplasms; Metalloporphyrins; Microscopy, Confocal; Mitochondria; Mitochondrial Proteins; Oxidants; Oxygen Consumption; Protoporphyrins; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Superoxide Dismutase; Transcription Factors; Uncoupling Protein 2 | 2014 |
Intraoperative Detection of Superficial Liver Tumors by Fluorescence Imaging Using Indocyanine Green and 5-aminolevulinic Acid.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Diagnostic Imaging; Female; Fluorescence; Fluorescent Dyes; Hepatectomy; Humans; Indocyanine Green; Liver Neoplasms; Male; Middle Aged; Sensitivity and Specificity; Ultrasonography | 2016 |
Photodynamic Diagnosis of Hepatocellular Carcinoma Using 5-Aminolevulinic Acid.
Topics: Aged; Aminolevulinic Acid; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Embolization, Therapeutic; Female; Hep G2 Cells; Humans; Liver; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Microscopy, Fluorescence; Middle Aged; Photochemotherapy; Photosensitizing Agents; Protoporphyrins | 2016 |
The utility of 5-aminolevulinic acid-mediated photodynamic diagnosis in the detection of intraoperative bile leakage.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Anastomotic Leak; Bile; Child; Child, Preschool; Female; Hepatectomy; Humans; Infant; Infant, Newborn; Intraoperative Care; Intraoperative Complications; Liver Neoplasms; Male; Middle Aged; Optical Imaging; Photosensitizing Agents; Retrospective Studies; Young Adult | 2017 |
Staging laparoscopy using ALA-mediated photodynamic diagnosis improves the detection of peritoneal metastases in advanced gastric cancer.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Animals; Disease Models, Animal; Female; Fluorescence; Humans; Laparoscopy; Light; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Middle Aged; Neoplasm Invasiveness; Neoplasm Staging; Peritoneal Neoplasms; Photosensitizing Agents; Serous Membrane; Stomach Neoplasms | 2012 |
Staging fluorescence laparoscopy for gastric cancer by using 5-aminolevulinic acid.
Topics: Administration, Oral; Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Fluorescence; Humans; Laparoscopy; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Peritoneal Neoplasms; Stomach Neoplasms | 2012 |
Comparison of 5-aminolevulinic acid and its hexylester mediated photodynamic action on human hepatoma cells.
Topics: Aminolevulinic Acid; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Tumor Cells, Cultured | 2002 |
Feasibility and diagnostic impact of fluorescence-based diagnostic laparoscopy in hepatocellular carcinoma: a case report.
Topics: Aged; Aminolevulinic Acid; Carcinoma, Hepatocellular; Female; Fluorescence; Humans; Laparoscopy; Light; Liver Neoplasms; Neoplasm Metastasis; Neoplasm Staging; Photosensitizing Agents | 2002 |
Improved preoperative tumor staging by 5-aminolevulinic acid induced fluorescence laparoscopy.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Digestive System Neoplasms; Female; Fluorescence; Humans; Laparoscopy; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging; Peritoneal Neoplasms | 2005 |
Laparoscopic fluorescence diagnosis of peritoneal metastases from human hepatoblastoma in nude rats.
Topics: Aminolevulinic Acid; Animals; Cell Line, Tumor; Disease Models, Animal; Fluorescence; Fluorescent Dyes; Hepatoblastoma; Humans; Laparoscopy; Liver Neoplasms; Neoplasm Transplantation; Peritoneal Neoplasms; Rats | 2006 |
Study of the efficacy and mechanism of ALA-mediated photodynamic therapy on human hepatocellular carcinoma cell.
Topics: Aminolevulinic Acid; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Drug Therapy, Combination; Humans; Liver Neoplasms; Photochemotherapy; Photosensitizing Agents; Protoporphyrins; Tissue Distribution; Treatment Outcome; Tumor Suppressor Protein p53 | 2007 |
5-aminolevulinic acid-mediated photodynamic therapy on Hep-2 and MCF-7c3 cells.
Topics: Adenocarcinoma; Aminolevulinic Acid; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Deferoxamine; Dose-Response Relationship, Drug; Drug Combinations; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Light; Liver Neoplasms; Microscopy, Fluorescence; Photochemotherapy; Photosensitizing Agents; Protoporphyrins | 2007 |
Effects of phenyl derivatives of dihydropyrazines with ability to generate radical species on Escherichia coli.
Topics: Aminolevulinic Acid; Copper; DNA; DNA Repair; Electron Spin Resonance Spectroscopy; Escherichia coli K12; Liver Neoplasms; Mutation; Phenyl Ethers; Pyrazines; Tetrazolium Salts | 2007 |
[Skull metastasis of hepatocellular carcinoma successfully treated by intraoperative photodynamic diagnosis using 5-aminolevulinic acid: case report].
Topics: Aminolevulinic Acid; Carcinoma, Hepatocellular; Fluorescence; Humans; Intraoperative Period; Liver Neoplasms; Male; Middle Aged; Skull Neoplasms; Tomography, X-Ray Computed | 2007 |
Aberrant porphyrin metabolism in hepatocellular carcinoma.
Topics: Adult; Aged; Aminolevulinic Acid; Carcinoma, Hepatocellular; Erythrocytes; Female; Humans; Injections, Intravenous; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Porphyrins | 1984 |
Photosensitization of experimental hepatocellular carcinoma with protoporphyrin synthesized from administered delta-aminolevulinic acid: studies with cultured cells and implanted tumors.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Hepatocellular; In Vitro Techniques; Laser Therapy; Liver; Liver Neoplasms; Male; Necrosis; Neoplasm Transplantation; Photochemotherapy; Photolysis; Photosensitizing Agents; Protoporphyrins; Rats; Rats, Sprague-Dawley; Reference Values | 1997 |
Laser Doppler perfusion imaging: new technique for determination of perfusion and reperfusion of splanchnic organs and tumor tissue.
Topics: Aminolevulinic Acid; Animals; Azepines; Intestines; Ischemia; Laser-Doppler Flowmetry; Liver; Liver Neoplasms; Pancreas; Photochemotherapy; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Regional Blood Flow; Splanchnic Circulation; Spleen; Stomach; Triazoles | 1997 |
DNA alkylation by 4,5-dioxovaleric acid, the final oxidation product of 5-aminolevulinic acid.
Topics: Alkylation; Aminolevulinic Acid; DNA Adducts; DNA Damage; Guanine; Humans; Liver Neoplasms; Mutagenesis; Oxidation-Reduction; Porphyria, Acute Intermittent; Valerates | 1998 |
Delta-aminolevulinic acid cytotoxic effects on human hepatocarcinoma cell lines.
Topics: Aminolevulinic Acid; Carcinoma, Hepatocellular; Cell Cycle; DNA Fragmentation; DNA, Neoplasm; Dose-Response Relationship, Drug; Glucose; Hemin; Humans; Liver Neoplasms; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2002 |
Is 5-aminolevulinic acid involved in the hepatocellular carcinogenesis of acute intermittent porphyria?
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aminolevulinic Acid; Animals; Deoxyguanosine; DNA; DNA Damage; Liver Neoplasms; Metals; Plasmids; Porphyria, Acute Intermittent; Propionates; Pyrazines; Rats; Valerates | 2002 |
Homotransplantation of the liver in a patient with hepatoma and hereditary tyrosinemia.
Topics: Aminolevulinic Acid; Carcinoma, Hepatocellular; Child; Female; Fructose-Bisphosphate Aldolase; Humans; Liver Neoplasms; Liver Transplantation; Phenylalanine; Porphobilinogen Synthase; Transplantation, Homologous; Tyrosine; Zinc | 1978 |
Influence of hepatic tumors caused by diethylnitrosamine on hexachlorobenzene-induced porphyria in rats.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Carcinoma, Hepatocellular; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Female; Ferrochelatase; Hexachlorobenzene; Liver; Liver Neoplasms; Porphobilinogen; Porphyrias; Porphyrins; Rats | 1991 |
Porphyrin synthesis by human hepatocytes and HepG2 cells--effects of enzyme inducers and delta-aminolevulinic acid.
Topics: Aminolevulinic Acid; Carcinoma, Hepatocellular; Cells, Cultured; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Enzyme Induction; Hexachlorobenzene; Humans; Hydroxymethylbilane Synthase; Liver; Liver Neoplasms; Methylcholanthrene; Phenobarbital; Porphyrins; Tumor Cells, Cultured; Uroporphyrinogen Decarboxylase | 1991 |
The Combination of Glycolytic Inhibitor 2-Deoxyglucose and Microbubbles Increases the Effect of 5-Aminolevulinic Acid-Sonodynamic Therapy in Liver Cancer Cells.
Topics: Aminolevulinic Acid; Antimetabolites; Cell Line, Tumor; Cell Survival; Combined Modality Therapy; Deoxyglucose; Humans; Levulinic Acids; Liver Neoplasms; Microbubbles; Ultrasonic Therapy | 2017 |