aminolevulinic acid has been researched along with Cancer of Head in 30 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This limits the treatment of basal cell carcinoma (non-melanoma skin cancer) to superficial forms and nodular therapy (only in aesthetically desired locations)." | 2.73 | Combination of Er:YAG laser and photodynamic therapy in the treatment of nodular basal cell carcinoma. ( Smucler, R; Vlk, M, 2008) |
| "5-Aminolevulinic acid (5-ALA) is a useful agent to enhance the detection of early epithelial lesions in head and neck cancers." | 2.71 | Excretion measurement of porphyrins and their precursors after topical administration of 5-aminolaevulinic acid for fluorescence endoscopy in head and neck cancer. ( Brossmann, P; Doss, MO; Gross, U; Klahr, N; Klein, M; Külkens, C; Lippert, BM; Ney, M; Teymoortash, A; Werner, JA, 2003) |
| "The reported numbers of PMDS and HNSCC ranged between 5 and 225." | 2.58 | Photodynamic treatment outcomes of potentially-malignant lesions and malignancies of the head and neck region: A systematic review. ( Choudhary, MG; Gadbail, AR; Gondivkar, SM; Likhitkar, MS; Vedpathak, PR, 2018) |
| "Additionally, a oral cancer Xenograft model of nude mice was built to test its inhibitive effect on the cancerous growth in vivo." | 1.62 | Co-delivery of chitosan nanoparticles of 5-aminolevulinic acid and shGBAS for improving photodynamic therapy efficacy in oral squamous cell carcinomas. ( Li, S; Liu, H; Wang, X, 2021) |
| "Human head and neck cancer cells AMC-HN3 were treated with cisplatin- and ALA-mediated PDT individually, and also in combination." | 1.40 | Cisplatin enhances the efficacy of 5-aminolevulinic acid mediated photodynamic therapy in human head and neck squamous cell carcinoma. ( Ahn, JC; Biswas, R; Chung, PS; Lee, YK; Mondal, A, 2014) |
| "Head and neck cancer (HNC) ranks the fourth leading malignancy and cancer death in male population in Taiwan." | 1.40 | Photodynamic therapy with 5-aminolevulinic acid (ALA) impairs tumor initiating and chemo-resistance property in head and neck cancer-derived cancer stem cells. ( Yu, CC; Yu, CH, 2014) |
| "Clear cell Bowen's disease (BD) is a rare histopathological subtype of BD, characterized by epidermal atypical keratinocytes with clear-cell changes exceeding 80% of the tumor population." | 1.36 | Warty and clear-cell Bowen's disease successfully treated with photodynamic treatment. ( Sezer, E; Yuksek, J, 2010) |
| "Head and neck cancer is highly invasive." | 1.34 | Photodynamic therapy suppresses the migration and invasion of head and neck cancer cells in vitro. ( Chen, CT; Lou, PJ; Wang, CP; Yang, TH, 2007) |
| "It has a tendency to metastasise to regional or distant sites after incomplete treatment." | 1.34 | Photodynamic therapy suppresses the migration and invasion of head and neck cancer cells in vitro. ( Chen, CT; Lou, PJ; Wang, CP; Yang, TH, 2007) |
| " We have investigated the effect of 5-ALA mediated PDT in combination with gamma-irradiation on the colony forming ability of several human head and neck tumour cell lines." | 1.31 | Effect of photodynamic therapy in combination with ionizing radiation on human squamous cell carcinoma cell lines of the head and neck. ( Allman, R; Cowburn, P; Mason, M, 2000) |
| "The two principal locations of the 10 Bowen's disease lesions were the leg (50%) and the trunk (40%)." | 1.29 | Photodynamic therapy of non-melanoma malignant tumours of the skin using topical delta-amino levulinic acid sensitization and laser irradiation. ( Andersson, T; Andersson-Engels, S; Berg, R; Johansson, J; Killander, D; Stenram, U; Svanberg, K; Svanberg, S; Wang, I, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (10.00) | 18.2507 |
| 2000's | 7 (23.33) | 29.6817 |
| 2010's | 16 (53.33) | 24.3611 |
| 2020's | 4 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, J | 1 |
| Wang, K | 1 |
| Liang, J | 1 |
| Jin, J | 1 |
| Wang, X | 4 |
| Yan, S | 1 |
| Yan, J | 1 |
| Wang, P | 2 |
| Li, L | 1 |
| Zhang, L | 2 |
| Zhang, G | 2 |
| Tang, Y | 1 |
| Li, S | 1 |
| Liu, H | 1 |
| Zhou, Z | 1 |
| Shi, L | 1 |
| Zeng, Q | 1 |
| Zhu, L | 1 |
| Gondivkar, SM | 1 |
| Gadbail, AR | 1 |
| Choudhary, MG | 1 |
| Vedpathak, PR | 1 |
| Likhitkar, MS | 1 |
| Shokrollahi, K | 1 |
| Javed, M | 1 |
| Aeuyung, K | 1 |
| Ghattaura, A | 1 |
| Whitaker, IS | 1 |
| O'Leary, B | 1 |
| James, W | 1 |
| Murison, M | 1 |
| Ahn, JC | 1 |
| Biswas, R | 1 |
| Mondal, A | 1 |
| Lee, YK | 1 |
| Chung, PS | 1 |
| Yu, CH | 1 |
| Yu, CC | 1 |
| Calista, D | 1 |
| Youssef, AA | 1 |
| Reygagne, P | 1 |
| Qiao, L | 1 |
| Mei, Z | 1 |
| Yang, Z | 1 |
| Li, X | 1 |
| Cai, H | 1 |
| Liu, W | 1 |
| Ahn, PH | 1 |
| Quon, H | 2 |
| O'Malley, BW | 1 |
| Weinstein, G | 1 |
| Chalian, A | 1 |
| Malloy, K | 2 |
| Atkins, JH | 1 |
| Sollecito, T | 1 |
| Greenberg, M | 1 |
| McNulty, S | 1 |
| Lin, A | 1 |
| Zhu, TC | 1 |
| Finlay, JC | 1 |
| Cengel, K | 1 |
| Livolsi, V | 1 |
| Feldman, M | 1 |
| Mick, R | 1 |
| Busch, TM | 2 |
| Hambly, RA | 1 |
| Mansoor, N | 1 |
| Quinlan, C | 1 |
| Shah, Z | 1 |
| Lenane, P | 1 |
| Ralph, N | 1 |
| Moloney, FJ | 1 |
| Apalla, Z | 1 |
| Sotiriou, E | 1 |
| Chovarda, E | 1 |
| Lefaki, I | 1 |
| Devliotou-Panagiotidou, D | 1 |
| Ioannides, D | 1 |
| Sezer, E | 1 |
| Yuksek, J | 1 |
| Liutkeviciūte-Navickiene, J | 1 |
| Mordas, A | 1 |
| Simkute, S | 1 |
| Bloznelyte-Plesniene, L | 1 |
| Fantini, F | 1 |
| Greco, A | 1 |
| Del Giovane, C | 1 |
| Cesinaro, AM | 1 |
| Venturini, M | 1 |
| Zane, C | 1 |
| Surrenti, T | 1 |
| Peris, K | 1 |
| Calzavara-Pinton, PG | 1 |
| Grossman, CE | 1 |
| King, RL | 1 |
| Putt, M | 1 |
| Donaldson, K | 1 |
| Kricka, L | 1 |
| Finlay, J | 1 |
| Zhu, T | 1 |
| Dimofte, A | 1 |
| Cengel, KA | 1 |
| Kraft, M | 1 |
| Betz, CS | 1 |
| Leunig, A | 1 |
| Arens, C | 1 |
| Goldberg, LH | 1 |
| Landau, JM | 1 |
| Moody, MN | 1 |
| Marquez, D | 1 |
| Jih, M | 1 |
| Kimyai-Asadi, A | 1 |
| Friedman, PM | 1 |
| Busch, A | 1 |
| Vergilis-Kalner, IJ | 1 |
| Debu, A | 1 |
| Bessis, D | 1 |
| Girard, C | 1 |
| Du Thanh, A | 1 |
| Guillot, B | 1 |
| Dereure, O | 1 |
| Umegaki, N | 1 |
| Moritsugu, R | 1 |
| Katoh, S | 1 |
| Harada, K | 1 |
| Nakano, H | 1 |
| Tamai, K | 1 |
| Hanada, K | 1 |
| Tanaka, M | 1 |
| Lippert, BM | 1 |
| Gross, U | 1 |
| Klein, M | 1 |
| Külkens, C | 1 |
| Klahr, N | 1 |
| Brossmann, P | 1 |
| Teymoortash, A | 1 |
| Ney, M | 1 |
| Doss, MO | 1 |
| Werner, JA | 1 |
| Yang, TH | 1 |
| Chen, CT | 1 |
| Wang, CP | 1 |
| Lou, PJ | 1 |
| Smucler, R | 1 |
| Vlk, M | 1 |
| Svanberg, K | 2 |
| Andersson, T | 1 |
| Killander, D | 1 |
| Wang, I | 2 |
| Stenram, U | 1 |
| Andersson-Engels, S | 1 |
| Berg, R | 1 |
| Johansson, J | 1 |
| Svanberg, S | 2 |
| Dilkes, MG | 1 |
| DeJode, ML | 1 |
| Gardiner, Q | 1 |
| Kenyon, GS | 1 |
| McKelvie, P | 1 |
| Clemente, LP | 1 |
| Pratas, RM | 1 |
| Cardoso, E | 1 |
| Clemente, MP | 1 |
| Montán, S | 1 |
| Allman, R | 1 |
| Cowburn, P | 1 |
| Mason, M | 1 |
| Morton, CA | 1 |
| Burden, AD | 1 |
2 reviews available for aminolevulinic acid and Cancer of Head
| Article | Year |
|---|---|
Photodynamic treatment outcomes of potentially-malignant lesions and malignancies of the head and neck region: A systematic review.
Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Chlorophyllides; Databases, Factual; Dihematoporphyri | 2018 |
Value of fluorescence endoscopy for the early diagnosis of laryngeal cancer and its precursor lesions.
Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Early Detection of Cancer; Endoscopy; Fluorescence; H | 2011 |
5 trials available for aminolevulinic acid and Cancer of Head
| Article | Year |
|---|---|
Toxicities and early outcomes in a phase 1 trial of photodynamic therapy for premalignant and early stage head and neck tumors.
Topics: Aged; Aminolevulinic Acid; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Male; | 2016 |
Skin cancer: preventive photodynamic therapy in patients with face and scalp cancerization. A randomized placebo-controlled study.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Facia | 2010 |
Interference with the Jaffé method for creatinine following 5-aminolevulinic acid administration.
Topics: Aminolevulinic Acid; Creatinine; Head and Neck Neoplasms; Humans; Kidney Function Tests; Photochemot | 2010 |
Excretion measurement of porphyrins and their precursors after topical administration of 5-aminolaevulinic acid for fluorescence endoscopy in head and neck cancer.
Topics: Administration, Topical; Aged; Aminolevulinic Acid; Carcinoma in Situ; Carcinoma, Squamous Cell; Fec | 2003 |
Combination of Er:YAG laser and photodynamic therapy in the treatment of nodular basal cell carcinoma.
Topics: Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Combined Modality Therapy; Follow-Up Studies; Head | 2008 |
23 other studies available for aminolevulinic acid and Cancer of Head
| Article | Year |
|---|---|
Chitosan-tripolyphosphate nanoparticles-mediated co-delivery of MTHFD1L shRNA and 5-aminolevulinic acid for combination photodynamic-gene therapy in oral cancer.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Chitosan; Genetic Therapy; | 2021 |
Surgery sequential with 5-Aminolevulinic acid photodynamic therapy for lip squamous cell carcinoma: Two cases reports.
Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Lip; Photochemothera | 2020 |
Co-delivery of chitosan nanoparticles of 5-aminolevulinic acid and shGBAS for improving photodynamic therapy efficacy in oral squamous cell carcinomas.
Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Cell Line, Tumor; Chitosan; Head and Neck Ne | 2021 |
5-Aminolevulinic acid photodynamic therapy for early-stage lip squamous cell carcinoma.
Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; China; Head and Neck Neoplasms; Humans; Lip; Neoplasm | 2021 |
Combined carbon dioxide laser with photodynamic therapy for nodular and superficial basal cell carcinoma.
Topics: Aged; Aminolevulinic Acid; Carcinoma, Basal Cell; Combined Modality Therapy; Female; Follow-Up Studi | 2014 |
Cisplatin enhances the efficacy of 5-aminolevulinic acid mediated photodynamic therapy in human head and neck squamous cell carcinoma.
Topics: Aminolevulinic Acid; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line, Tumor; Cel | 2014 |
Photodynamic therapy with 5-aminolevulinic acid (ALA) impairs tumor initiating and chemo-resistance property in head and neck cancer-derived cancer stem cells.
Topics: Aldehyde Dehydrogenase 1 Family; Aminolevulinic Acid; Biomarkers, Tumor; Cell Line, Tumor; Cell Tran | 2014 |
Development of squamous cell carcinoma after photodynamic therapy with methyl aminoleuvulinate.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Squamous Cell; Female; Head and Neck Neopla | 2014 |
Successful treatment of extramammary Paget's disease of the scalp with photodynamic therapy.
Topics: Aged, 80 and over; Aminolevulinic Acid; Head and Neck Neoplasms; Humans; Male; Paget Disease, Extram | 2016 |
ALA-PDT inhibits proliferation and promotes apoptosis of SCC cells through STAT3 signal pathway.
Topics: Aminolevulinic Acid; Apoptosis; Cell Line, Tumor; Cell Proliferation; Head and Neck Neoplasms; Human | 2016 |
Factors predicting pain and effect of oral analgesia in topical photodynamic therapy.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Analgesics; Bowen's Disea | 2017 |
Warty and clear-cell Bowen's disease successfully treated with photodynamic treatment.
Topics: Administration, Topical; Aged; Aminolevulinic Acid; Bowen's Disease; Head and Neck Neoplasms; Humans | 2010 |
[Fluorescence diagnostics of skin tumors using 5-aminolevulinic acid and its methyl ester].
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Carcinoma, Squamous Cell | 2009 |
Photodynamic therapy for basal cell carcinoma: clinical and pathological determinants of response.
Topics: Age Factors; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Extremities; Femal | 2011 |
Evaluation of the chemopreventative effects of ALA PDT in patients with multiple actinic keratoses and a history of skin cancer.
Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Facial Neoplasms; Female; Follow-Up Studies; He | 2012 |
Photodynamic therapy with methyl aminolaevulinate for cervical and/or facial lesions of folliculotropic mycosis fungoides: interest and limits.
Topics: Aged; Aminolevulinic Acid; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Mycosis Fungo | 2013 |
Photodynamic therapy may be useful in debulking cutaneous lymphoma prior to radiotherapy.
Topics: Administration, Topical; Aged; Aminolevulinic Acid; Combined Modality Therapy; Female; Head and Neck | 2004 |
Photodynamic therapy suppresses the migration and invasion of head and neck cancer cells in vitro.
Topics: Aminolevulinic Acid; Cell Line, Tumor; Cell Movement; Cell Survival; Collagen; Drug Combinations; Ex | 2007 |
Photodynamic therapy of non-melanoma malignant tumours of the skin using topical delta-amino levulinic acid sensitization and laser irradiation.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Arm; Bowen's Disease; | 1994 |
Treatment of head and neck cancer with photodynamic therapy: results after one year.
Topics: Aminolevulinic Acid; Antineoplastic Agents; Head and Neck Neoplasms; Hematoporphyrin Derivative; Hum | 1995 |
Fluorescence diagnostics and kinetic studies in the head and neck region utilizing low-dose delta-aminolevulinic acid sensitization.
Topics: Administration, Oral; Adult; Aged; Aminolevulinic Acid; Dose-Response Relationship, Drug; Endoscopy; | 1999 |
Effect of photodynamic therapy in combination with ionizing radiation on human squamous cell carcinoma cell lines of the head and neck.
Topics: Aminolevulinic Acid; Carcinoma, Squamous Cell; Cell Cycle; Cell Survival; Combined Modality Therapy; | 2000 |
Treatment of multiple scalp basal cell carcinomas by photodynamic therapy.
Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Female; Follow-Up Studies; Head and Neck Neoplasms; Hu | 2001 |