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aminolevulinic acid and Cancer of Gastrointestinal Tract

aminolevulinic acid has been researched along with Cancer of Gastrointestinal Tract in 18 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (44.44)18.2507
2000's5 (27.78)29.6817
2010's4 (22.22)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Grosenick, D1
Bremer, C1
Kawai, N1
Hirohashi, Y1
Ebihara, Y1
Saito, T2
Murai, A1
Shirosaki, T1
Kubo, T1
Nakatsugawa, M1
Kanaseki, T1
Tsukahara, T1
Shichinohe, T1
Li, L1
Hirano, S1
Torigoe, T1
Ramonaite, R1
Petrolis, R1
Unay, S1
Kiudelis, G1
Skieceviciene, J1
Kupcinskas, L1
Bilgin, MD1
Krisciukaitis, A1
Matsusaka, S1
Kozuka, M1
Takagi, H1
Ito, H1
Minowa, S1
Hirai, M1
Hatake, K1
Isomoto, H1
Nanashima, A1
Senoo, T1
Ogiwara, K1
Hashisako, M1
Ohnita, K1
Yamaguchi, N1
Kunizaki, M1
Hidaka, S1
Fukuda, H1
Ishii, H1
Matsushima, K1
Minami, H1
Akazawa, Y1
Takeshima, F1
Fukuoka, J1
Nagayasu, T1
Nakao, K1
Endlicher, E2
Messmann, H6
Mĺkvy, P2
Regula, J2
Conio, M2
Pauer, M2
Millson, CE2
MacRobert, AJ2
Bown, SG2
Gossner, L2
Sroka, R1
Hahn, EG1
Ell, C2
Webber, J2
Kessel, D2
Fromm, D2
Marcus, SL1
Sobel, RS1
Golub, AL1
Carroll, RL1
Lundahl, S1
Shulman, DG1
Knüchel, R1
Hauser, T1
Szeimies, RM1
Kullmann, F1
Bäumler, W1
Schölmerich, J1
Gahlen, J1
Stern, J1
Laubach, HH1
Pietschmann, M1
Herfarth, C1
Orth, K1
Russ, D1
Steiner, R1
Beger, HG1
May, A1

Reviews

5 reviews available for aminolevulinic acid and Cancer of Gastrointestinal Tract

ArticleYear
Fluorescence Imaging of Breast Tumors and Gastrointestinal Cancer.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 2020, Volume: 216

    Topics: Aminolevulinic Acid; Barrett Esophagus; Breast Neoplasms; Female; Fluorescence; Gastrointestinal Neo

2020
Photodynamic diagnosis in the gastrointestinal tract.
    Gastrointestinal endoscopy clinics of North America, 2004, Volume: 14, Issue:3

    Topics: Aminolevulinic Acid; Endoscopy, Gastrointestinal; Fluorescence; Gastrointestinal Neoplasms; Humans;

2004
Photodynamic therapy (PDT) and photodiagnosis (PD) using endogenous photosensitization induced by 5-aminolevulinic acid (ALA): current clinical and development status.
    Journal of clinical laser medicine & surgery, 1996, Volume: 14, Issue:2

    Topics: Aminolevulinic Acid; Animals; Endometrium; Female; Gastrointestinal Neoplasms; Humans; Laser Therapy

1996
[Fluorescence endoscopy in gastroenterology].
    Zeitschrift fur Gastroenterologie, 2000, Volume: 38, Issue:1

    Topics: Aminolevulinic Acid; Barrett Esophagus; Colitis, Ulcerative; Colonic Neoplasms; Endoscopy, Gastroint

2000
5-Aminolevulinic acid-induced protoporphyrin IX for the detection of gastrointestinal dysplasia.
    Gastrointestinal endoscopy clinics of North America, 2000, Volume: 10, Issue:3

    Topics: Aminolevulinic Acid; Animals; Endoscopy, Gastrointestinal; Gastrointestinal Neoplasms; Humans; Intes

2000

Trials

3 trials available for aminolevulinic acid and Cancer of Gastrointestinal Tract

ArticleYear
Sensitization and photodynamic therapy (PDT) of gastrointestinal tumors with 5-aminolaevulinic acid (ALA) induced protoporphyrin IX (PPIX). A pilot study.
    Neoplasma, 1995, Volume: 42, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Biotransformation; Female

1995
Side effects and photosensitization of human tissues after aminolevulinic acid.
    The Journal of surgical research, 1997, Feb-15, Volume: 68, Issue:1

    Topics: Adenocarcinoma; Administration, Oral; Aminolevulinic Acid; Female; Gastrointestinal Neoplasms; Human

1997
Photodynamic therapy for gastrointestinal tumors using three photosensitizers--ALA induced PPIX, Photofrin and MTHPC. A pilot study.
    Neoplasma, 1998, Volume: 45, Issue:3

    Topics: Adult; Aged; Aminolevulinic Acid; Dihematoporphyrin Ether; Duodenal Neoplasms; Esophageal Neoplasms;

1998

Other Studies

10 other studies available for aminolevulinic acid and Cancer of Gastrointestinal Tract

ArticleYear
ABCG2 expression is related to low 5-ALA photodynamic diagnosis (PDD) efficacy and cancer stem cell phenotype, and suppression of ABCG2 improves the efficacy of PDD.
    PloS one, 2019, Volume: 14, Issue:5

    Topics: Aminolevulinic Acid; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; Cell Line, Tu

2019
Mathematical morphology-based imaging of gastrointestinal cancer cell motility and 5-aminolevulinic acid-induced fluorescence.
    Biomedizinische Technik. Biomedical engineering, 2019, Dec-18, Volume: 64, Issue:6

    Topics: Aminolevulinic Acid; Cell Movement; Fluorescence; Gastrointestinal Neoplasms; Humans; Levulinic Acid

2019
A novel detection strategy for living circulating tumor cells using 5-aminolevulinic acid.
    Cancer letters, 2014, Dec-01, Volume: 355, Issue:1

    Topics: Aminolevulinic Acid; Cell Line, Tumor; Cell Separation; Cell Survival; Filtration; Gastrointestinal

2014
In vivo fluorescence navigation of gastric and upper gastrointestinal tumors by 5-aminolevulinic acid mediated photodynamic diagnosis with a laser-equipped video image endoscope.
    Photodiagnosis and photodynamic therapy, 2015, Volume: 12, Issue:2

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Signet Ring Cell; En

2015
Photodynamic therapy: successful destruction of gastrointestinal cancer after oral administration of aminolevulinic acid.
    Gastrointestinal endoscopy, 1995, Volume: 41, Issue:1

    Topics: Adenocarcinoma; Administration, Oral; Aged; Aged, 80 and over; Aminolevulinic Acid; Esophageal Neopl

1995
On-line fluorescence of human tissues after oral administration of 5-aminolevulinic acid.
    Journal of photochemistry and photobiology. B, Biology, 1997, Volume: 38, Issue:2-3

    Topics: Administration, Oral; Aminolevulinic Acid; Drug Administration Schedule; Gastrointestinal Neoplasms;

1997
[Photodynamic diagnosis of gastrointestinal precancerous lesions after sensitization with 5-aminolevulinic acid. A pilot study].
    Deutsche medizinische Wochenschrift (1946), 1998, Apr-24, Volume: 123, Issue:17

    Topics: Adenoma; Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Colitis, Ulcerative; Colorectal Neopla

1998
Improving diagnostic staging laparoscopy using intraperitoneal lavage of delta-aminolevulinic acid (ALA) for laparoscopic fluorescence diagnosis.
    Surgery, 1999, Volume: 126, Issue:3

    Topics: Aminolevulinic Acid; Animals; Colonic Neoplasms; Fluorescence; Gastrointestinal Neoplasms; Humans; L

1999
Fluorescence detection of small gastrointestinal tumours: principles, technique, first clinical experience.
    Langenbeck's archives of surgery, 2000, Volume: 385, Issue:7

    Topics: Aminolevulinic Acid; Endoscopy; Fluorescence; Gastrointestinal Neoplasms; Humans; Laparoscopy; Perit

2000
[Early detection of gastrointestinal tumors. Guided biopsy with fluorescence].
    MMW Fortschritte der Medizin, 2002, Mar-28, Volume: 144, Issue:13

    Topics: Aminolevulinic Acid; Biopsy; Diagnosis, Differential; Endoscopy, Gastrointestinal; Gastric Mucosa; G

2002