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aminolevulinic acid and Cancer, Radiation-Induced

aminolevulinic acid has been researched along with Cancer, Radiation-Induced in 17 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Research Excerpts

ExcerptRelevanceReference
"Photodynamic therapy (PDT) with topical application of delta-aminolevulinic acid (ALA) followed by irradiation with visible light (ALA-PDT) is a relatively new and promising experimental treatment of superficial premalignant and malignant skin neoplasms."3.69Photodynamic therapy with topical delta-aminolevulinic acid delays UV photocarcinogenesis in hairless mice. ( Bech-Thomsen, N; Poulsen, T; Stender, IM; Wulf, HC, 1997)
"The concept of skin cancer prevention with photodynamic therapy has evolved over the past few years to include large surface application of aminolevulinic acid or methyl aminolevulinate followed by light exposure to prevent the development of new lesions."1.34Chemopreventative thoughts for photodynamic therapy. ( Bissonnette, R, 2007)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (23.53)18.2507
2000's9 (52.94)29.6817
2010's4 (23.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, H1
Li, J1
Lv, T1
Tu, Q1
Huang, Z1
Wang, X1
Fargnoli, MC1
Kostaki, D1
Piccioni, A1
Di Stefani, A1
Peris, K1
Togsverd-Bo, K1
Lerche, CM1
Poulsen, T2
Wulf, HC2
Haedersdal, M1
García Martín, E1
Fernández Tirado, FJ1
Sharfaei, S1
Juzenas, P1
Moan, J1
Bissonnette, R3
van den Akker, JT2
Holroyd, JA1
Vernon, DI1
Sterenborg, HJ2
Brown, SB2
Podda, M1
Takahashi, H1
Nakajima, S1
Sakata, I1
Ishida-Yamamoto, A1
Iizuka, H1
Caty, V1
Liu, Y1
Viau, G1
Henderson, BW1
Vaughan, L1
Bellnier, DA1
van Leengoed, H1
Johnson, PG1
Oseroff, AR1
Lang, S1
Baumgartner, R1
Struck, R1
Leunig, A1
Gutmann, R1
Feyh, J1
Stender, IM1
Bech-Thomsen, N1
Robinson, DJ1
de Bruijn, HS2
van der Veen, N1
Stringer, MR1
Star, WM2
Beijersbergen van Henegouwen, GM1
Morton, CA1

Reviews

1 review available for aminolevulinic acid and Cancer, Radiation-Induced

ArticleYear
Photodynamic therapy for the treatment of microinvasive squamous cell carcinoma of the lower lip: a case report.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2015, Volume: 150, Issue:3

    Topics: Aged; Aminolevulinic Acid; Carcinoma, Squamous Cell; Cheilitis; Dermoscopy; Humans; Lip Neoplasms; M

2015

Other Studies

16 other studies available for aminolevulinic acid and Cancer, Radiation-Induced

ArticleYear
Therapeutic and immune effects of 5-aminolevulinic acid photodynamic therapy on UVB-induced squamous cell carcinomas in hairless mice.
    Experimental dermatology, 2013, Volume: 22, Issue:5

    Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Mice; Mice, Hairless; Neoplasms, Radiation-I

2013
Photodynamic therapy with topical methyl- and hexylaminolevulinate for prophylaxis and treatment of UV-induced SCC in hairless mice.
    Experimental dermatology, 2010, Volume: 19, Issue:8

    Topics: Administration, Topical; Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Disease Models, Ani

2010
[Periocular basal cell carcinoma treatment tendencies].
    Archivos de la Sociedad Espanola de Oftalmologia, 2010, Volume: 85, Issue:8

    Topics: Aminolevulinic Acid; Aminoquinolines; Antineoplastic Agents; Carcinoma, Basal Cell; Conjunctival Neo

2010
Weekly topical application of methyl aminolevulinate followed by light exposure delays the appearance of UV-induced skin tumours in mice.
    Archives of dermatological research, 2002, Volume: 294, Issue:5

    Topics: Administration, Cutaneous; Aminolevulinic Acid; Animals; Drug Administration Schedule; Mice; Mice, H

2002
[An unsurpassed duo in control of skin cancer. Metvix and Aktilite].
    Krankenpflege Journal, 2003, Volume: 41, Issue:1-3

    Topics: Administration, Topical; Aminolevulinic Acid; Carcinoma, Basal Cell; Cell Survival; Hematoporphyrin

2003
Chronic UVB exposure enhances in vitro percutaneous penetration of 5-aminulevulinic acid in hairless mouse skin.
    Lasers in surgery and medicine, 2004, Volume: 34, Issue:2

    Topics: Aminolevulinic Acid; Animals; Disease Models, Animal; Female; In Vitro Techniques; Mice; Mice, Hairl

2004
[Eliminating light-induced skin cancer without operation].
    Krankenpflege Journal, 2004, Volume: 42, Issue:3-4

    Topics: Administration, Topical; Aminolevulinic Acid; Carcinoma, Basal Cell; Hematoporphyrin Photoradiation;

2004
Photodynamic therapy using a novel photosensitizer, ATX-S10(Na): comparative effect with 5-aminolevulinic acid on squamous cell carcinoma cell line, SCC15, ultraviolet B-induced skin tumor, and phorbol ester-induced hyperproliferative skin.
    Archives of dermatological research, 2005, Volume: 296, Issue:10

    Topics: Aminolevulinic Acid; Animals; Cell Line; Cell Line, Tumor; Mice; Neoplasms, Radiation-Induced; Neopl

2005
Multiple large surface photodynamic therapy sessions with topical methylaminolaevulinate in PTCH heterozygous mice.
    The British journal of dermatology, 2006, Volume: 154, Issue:4

    Topics: Aminolevulinic Acid; Animals; Carcinoma, Basal Cell; Female; Genetic Predisposition to Disease; Hete

2006
Chemopreventative thoughts for photodynamic therapy.
    Dermatologic clinics, 2007, Volume: 25, Issue:1

    Topics: Aminolevulinic Acid; Animals; Carcinoma, Squamous Cell; Humans; Keratosis; Mice; Neoplasms, Radiatio

2007
Photosensitization of murine tumor, vasculature and skin by 5-aminolevulinic acid-induced porphyrin.
    Photochemistry and photobiology, 1995, Volume: 62, Issue:4

    Topics: Administration, Topical; Aminolevulinic Acid; Animals; Colonic Neoplasms; Coproporphyrins; Fibrosarc

1995
[Photodynamic diagnosis and therapy of neoplasms of the facial skin after topical administration of 5-aminolevulinic acid].
    Laryngo- rhino- otologie, 1995, Volume: 74, Issue:2

    Topics: Administration, Topical; Aged; Aged, 80 and over; Aminolevulinic Acid; Carcinoma, Basal Cell; Facial

1995
Photodynamic therapy with topical delta-aminolevulinic acid delays UV photocarcinogenesis in hairless mice.
    Photochemistry and photobiology, 1997, Volume: 66, Issue:4

    Topics: Administration, Topical; Aminolevulinic Acid; Animals; Female; Mice; Mice, Hairless; Neoplasms, Radi

1997
Protoporphyrin IX fluorescence photobleaching during ALA-mediated photodynamic therapy of UVB-induced tumors in hairless mouse skin.
    Photochemistry and photobiology, 1999, Volume: 69, Issue:1

    Topics: Aminolevulinic Acid; Animals; Female; Fluorescence; Male; Mice; Mice, Hairless; Neoplasms, Radiation

1999
Protoporphyrin IX fluorescence kinetics and localization after topical application of ALA pentyl ester and ALA on hairless mouse skin with UVB-induced early skin cancer.
    Photochemistry and photobiology, 2000, Volume: 72, Issue:3

    Topics: Administration, Topical; Aminolevulinic Acid; Animals; Fluorescence; Mice; Mice, Hairless; Neoplasms

2000
Topical photodynamic therapy in dermatology.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2001, Volume: 91, Issue:8

    Topics: Administration, Topical; Aminolevulinic Acid; Facial Neoplasms; Hematoporphyrin Photoradiation; Huma

2001