aminolevulinic acid has been researched along with Brain Edema in 6 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The optimization of fluorescence imaging of brain tumors differentiated from brain edema is possible in the case of 5-ALA within 6h, and also possible in the case of talaporfin sodium beyond 12h." | 7.75 | The optimization of fluorescence imaging of brain tumor tissue differentiated from brain edema--in vivo kinetic study of 5-aminolevulinic acid and talaporfin sodium. ( Matsuda, M; Matsumura, A; Nakai, K; Shirakawa, M; Tsurubuchi, T; Yamamoto, T; Yoshida, F; Zaboronok, A, 2009) |
| "Accumulation of protoporphyrin IX (PPIX) in malignant gliomas is induced by 5-aminolevulinic acid (5-ALA)." | 7.71 | Photoirradiation therapy of experimental malignant glioma with 5-aminolevulinic acid. ( Bise, K; Hundt, CS; Olzowy, B; Reulen, HJ; Stocker, S; Stummer, W, 2002) |
| "The optimization of fluorescence imaging of brain tumors differentiated from brain edema is possible in the case of 5-ALA within 6h, and also possible in the case of talaporfin sodium beyond 12h." | 3.75 | The optimization of fluorescence imaging of brain tumor tissue differentiated from brain edema--in vivo kinetic study of 5-aminolevulinic acid and talaporfin sodium. ( Matsuda, M; Matsumura, A; Nakai, K; Shirakawa, M; Tsurubuchi, T; Yamamoto, T; Yoshida, F; Zaboronok, A, 2009) |
| "Five-aminolevulinic acid (5-ALA) induces the specific accumulation of photosensitising porphyrins in malignant gliomas and has been explored for photo-irradiation therapy of these tumours." | 3.73 | Oedema formation in experimental photo-irradiation therapy of brain tumours using 5-ALA. ( Ito, S; Rachinger, W; Reulen, HJ; Stepp, H; Stummer, W, 2005) |
| "Accumulation of protoporphyrin IX (PPIX) in malignant gliomas is induced by 5-aminolevulinic acid (5-ALA)." | 3.71 | Photoirradiation therapy of experimental malignant glioma with 5-aminolevulinic acid. ( Bise, K; Hundt, CS; Olzowy, B; Reulen, HJ; Stocker, S; Stummer, W, 2002) |
| "Headache is common in PRES, though headache associated with PRES was not identified as a separate entity in the 2018 International Classification of Headache Disorders." | 2.72 | Posterior Reversible Encephalopathy Syndrome. ( Gao, V; Gewirtz, AN; Parauda, SC; Robbins, MS, 2021) |
| "Associations with PRES include renal failure, preeclampsia and eclampsia, autoimmune conditions, and immunosuppression." | 2.72 | Posterior Reversible Encephalopathy Syndrome. ( Gao, V; Gewirtz, AN; Parauda, SC; Robbins, MS, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Gewirtz, AN | 1 |
| Gao, V | 1 |
| Parauda, SC | 1 |
| Robbins, MS | 1 |
| Tsurubuchi, T | 1 |
| Zaboronok, A | 1 |
| Yamamoto, T | 1 |
| Nakai, K | 1 |
| Yoshida, F | 1 |
| Shirakawa, M | 1 |
| Matsuda, M | 1 |
| Matsumura, A | 1 |
| Reulen, HJ | 3 |
| Olzowy, B | 1 |
| Hundt, CS | 1 |
| Stocker, S | 1 |
| Bise, K | 1 |
| Stummer, W | 2 |
| Ito, S | 1 |
| Rachinger, W | 1 |
| Stepp, H | 1 |
| Goldstein, GW | 1 |
| Diamond, I | 1 |
1 review available for aminolevulinic acid and Brain Edema
| Article | Year |
|---|---|
Posterior Reversible Encephalopathy Syndrome.
Topics: Acute Chest Syndrome; Aminolevulinic Acid; Anemia, Sickle Cell; Autoimmune Diseases; Blood-Brain Bar | 2021 |
5 other studies available for aminolevulinic acid and Brain Edema
| Article | Year |
|---|---|
The optimization of fluorescence imaging of brain tumor tissue differentiated from brain edema--in vivo kinetic study of 5-aminolevulinic acid and talaporfin sodium.
Topics: Aminolevulinic Acid; Animals; Brain; Brain Edema; Brain Neoplasms; Diagnosis, Differential; Image En | 2009 |
Bulk flow and diffusion revisited, and clinical applications.
Topics: Aminolevulinic Acid; Animals; Brain Edema; Brain Neoplasms; Capillaries; Cerebrovascular Circulation | 2010 |
Photoirradiation therapy of experimental malignant glioma with 5-aminolevulinic acid.
Topics: Aminolevulinic Acid; Animals; Antineoplastic Agents; Brain; Brain Edema; Brain Neoplasms; Dihematopo | 2002 |
Oedema formation in experimental photo-irradiation therapy of brain tumours using 5-ALA.
Topics: Aminolevulinic Acid; Animals; Brain Edema; Brain Neoplasms; Dexamethasone; Disease Models, Animal; G | 2005 |
Metabolic basis of lead encephalopathy.
Topics: Adenosine Triphosphatases; Aminolevulinic Acid; Animals; Brain; Brain Diseases; Brain Edema; Cerebel | 1974 |