Page last updated: 2024-10-16

aminolevulinic acid and Blood Pressure, High

aminolevulinic acid has been researched along with Blood Pressure, High in 14 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Research Excerpts

ExcerptRelevanceReference
"These findings suggest that 5-ALA-HCl does not affect the antihypertensive agents-induced hypotensive effect, but enhances the bupivacaine-induced hypotensive effect, especially in SHRs, indicating that 5-ALA may contribute to anesthesia-induced hypotension via suppression of sympathetic nerve activity in patients with hypertension."8.315-Aminolevulinic acid hydrochloride enhances bupivacaine-induced hypotension in spontaneously hypertensive rats. ( Abe, M; Fukuda, N; Hara, T; Ishizuka, M; Ito, H; Katakawa, M; Otsuka, N, 2023)
"The acute hepatic porphyrias (AHP) are rare, inborn errors of heme-metabolism and include acute intermittent porphyria, hereditary coproporphyria, variegate porphyria, and porphyria due to severe deficiency of 5-aminolevulinic acid dehydratase."5.41AGA Clinical Practice Update on Diagnosis and Management of Acute Hepatic Porphyrias: Expert Review. ( Balwani, M; Bonkovsky, HL; Lim, JK; Wang, B, 2023)
"Arterial hypertension was defined as the blood pressure over 140/90 and/or early diagnosed hypertension."5.31[Influence of lead exposure on arterial hypertension]. ( Birkner, E; Dziwisz, M; Kasperczyk, A; Kasperczyk, S, 2002)
"These findings suggest that 5-ALA-HCl does not affect the antihypertensive agents-induced hypotensive effect, but enhances the bupivacaine-induced hypotensive effect, especially in SHRs, indicating that 5-ALA may contribute to anesthesia-induced hypotension via suppression of sympathetic nerve activity in patients with hypertension."4.315-Aminolevulinic acid hydrochloride enhances bupivacaine-induced hypotension in spontaneously hypertensive rats. ( Abe, M; Fukuda, N; Hara, T; Ishizuka, M; Ito, H; Katakawa, M; Otsuka, N, 2023)
"5-aminolevulinic acid hydrochloride is a highly effective drug in reducing tumor residuals in transurethral resection of the bladder tumors; however, hypotension is a serious side effect that causes clinical problems."4.31[Effectiveness of Pharmaceutical Intervention While Administering 5-Aminolevulinic Acid Hydrochloride through a Collaboration of Physicians and Pharmacists]. ( Aoyama, S; Kasahara, S; Komeda, H; Mizui, T; Tachi, T; Takai, A; Tanaka, K; Yasuda, M, 2023)
"However, pain and hypertension are important side effects of conventional PDT (c-PDT)."3.11Hemodynamic changes during conventional and daylight photodynamic therapy of actinic keratoses - a randomized controlled trial. ( Enk, A; Gholam, P; Hartmann, J; Keller, A, 2022)
"Pain was quantified using a visual analog scale."3.11Hemodynamic changes during conventional and daylight photodynamic therapy of actinic keratoses - a randomized controlled trial. ( Enk, A; Gholam, P; Hartmann, J; Keller, A, 2022)
"Acute intermittent porphyria is the most common type of AHP, with an estimated prevalence of patients with symptoms of approximately 1 in 100,000."3.01AGA Clinical Practice Update on Diagnosis and Management of Acute Hepatic Porphyrias: Expert Review. ( Balwani, M; Bonkovsky, HL; Lim, JK; Wang, B, 2023)
"The acute hepatic porphyrias (AHP) are rare, inborn errors of heme-metabolism and include acute intermittent porphyria, hereditary coproporphyria, variegate porphyria, and porphyria due to severe deficiency of 5-aminolevulinic acid dehydratase."3.01AGA Clinical Practice Update on Diagnosis and Management of Acute Hepatic Porphyrias: Expert Review. ( Balwani, M; Bonkovsky, HL; Lim, JK; Wang, B, 2023)
"Headache is common in PRES, though headache associated with PRES was not identified as a separate entity in the 2018 International Classification of Headache Disorders."2.72Posterior Reversible Encephalopathy Syndrome. ( Gao, V; Gewirtz, AN; Parauda, SC; Robbins, MS, 2021)
"Associations with PRES include renal failure, preeclampsia and eclampsia, autoimmune conditions, and immunosuppression."2.72Posterior Reversible Encephalopathy Syndrome. ( Gao, V; Gewirtz, AN; Parauda, SC; Robbins, MS, 2021)
"5-aminolevulinic acid hydrochloride is a highly effective drug in reducing tumor residuals in transurethral resection of the bladder tumors; however, hypotension is a serious side effect that causes clinical problems."1.91[Effectiveness of Pharmaceutical Intervention While Administering 5-Aminolevulinic Acid Hydrochloride through a Collaboration of Physicians and Pharmacists]. ( Aoyama, S; Kasahara, S; Komeda, H; Mizui, T; Tachi, T; Takai, A; Tanaka, K; Yasuda, M, 2023)
"Arterial hypertension was defined as the blood pressure over 140/90 and/or early diagnosed hypertension."1.31[Influence of lead exposure on arterial hypertension]. ( Birkner, E; Dziwisz, M; Kasperczyk, A; Kasperczyk, S, 2002)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's0 (0.00)18.2507
2000's3 (21.43)29.6817
2010's3 (21.43)24.3611
2020's6 (42.86)2.80

Authors

AuthorsStudies
Keller, A2
Hartmann, J2
Enk, A2
Gholam, P2
Wang, B1
Bonkovsky, HL1
Lim, JK1
Balwani, M1
Fukuda, N1
Katakawa, M1
Ito, H1
Hara, T1
Otsuka, N1
Ishizuka, M1
Abe, M1
Tanaka, K1
Tachi, T1
Takai, A1
Aoyama, S1
Yasuda, M1
Kasahara, S1
Komeda, H1
Mizui, T1
Gewirtz, AN1
Gao, V1
Parauda, SC1
Robbins, MS1
Borroni, RG1
Carugno, A1
Rivetti, N1
Arbustini, E1
Brazzelli, V1
Pallet, N1
Mami, I1
Schmitt, C1
Karim, Z1
François, A1
Rabant, M1
Nochy, D1
Gouya, L1
Deybach, JC1
Xu-Dubois, Y1
Thervet, E1
Puy, H1
Karras, A1
Bourque, SL1
Benjamin, CD1
Adams, MA1
Nakatsu, K1
Nomiyama, K1
Nomiyama, H1
Liu, SJ1
Tao, YX1
Nomiyama, T1
Omae, K1
Kasperczyk, S2
Dziwisz, M1
Kasperczyk, A2
Birkner, E2
Kasperczyk, J1
Boscolo, P1
Galli, G1
Iannaccone, A1
Martino, F1
Porcelli, G1
Troncone, L1
Carvalho, L1
Soares, MA1
da Costa, JN1

Reviews

2 reviews available for aminolevulinic acid and Blood Pressure, High

ArticleYear
AGA Clinical Practice Update on Diagnosis and Management of Acute Hepatic Porphyrias: Expert Review.
    Gastroenterology, 2023, Volume: 164, Issue:3

    Topics: Abdominal Pain; Aminolevulinic Acid; Antiemetics; Carcinoma, Hepatocellular; Creatinine; Female; Hem

2023
Posterior Reversible Encephalopathy Syndrome.
    Current pain and headache reports, 2021, Feb-25, Volume: 25, Issue:3

    Topics: Acute Chest Syndrome; Aminolevulinic Acid; Anemia, Sickle Cell; Autoimmune Diseases; Blood-Brain Bar

2021

Trials

1 trial available for aminolevulinic acid and Blood Pressure, High

ArticleYear
Hemodynamic changes during conventional and daylight photodynamic therapy of actinic keratoses - a randomized controlled trial.
    The Journal of dermatological treatment, 2022, Volume: 33, Issue:7

    Topics: Aminolevulinic Acid; Hemodynamics; Humans; Hypertension; Keratosis, Actinic; Pain; Photochemotherapy

2022

Other Studies

11 other studies available for aminolevulinic acid and Blood Pressure, High

ArticleYear
Pulse rate and blood pressure changes during low-irradiance PDT compared with conventional PDT in the treatment of facial actinic keratoses: A retrospective study.
    Photodermatology, photoimmunology & photomedicine, 2022, Volume: 38, Issue:5

    Topics: Aminolevulinic Acid; Blood Pressure; Heart Rate; Humans; Hypertension; Keratosis, Actinic; Pain; Pho

2022
5-Aminolevulinic acid hydrochloride enhances bupivacaine-induced hypotension in spontaneously hypertensive rats.
    Journal of pharmacological sciences, 2023, Volume: 152, Issue:1

    Topics: Aminolevulinic Acid; Amlodipine; Animals; Antihypertensive Agents; Blood Pressure; Bupivacaine; Hype

2023
[Effectiveness of Pharmaceutical Intervention While Administering 5-Aminolevulinic Acid Hydrochloride through a Collaboration of Physicians and Pharmacists].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2023, Volume: 50, Issue:11

    Topics: Aminolevulinic Acid; Antihypertensive Agents; Humans; Hypertension; Hypotension; Pharmaceutical Prep

2023
Risk of acute postoperative hypertension after topical photodynamic therapy for non-melanoma skin cancer.
    Photodermatology, photoimmunology & photomedicine, 2013, Volume: 29, Issue:2

    Topics: Age Factors; Aged; Aged, 80 and over; Aminolevulinic Acid; Blood Pressure; Bowen's Disease; Carcinom

2013
High prevalence of and potential mechanisms for chronic kidney disease in patients with acute intermittent porphyria.
    Kidney international, 2015, Volume: 88, Issue:2

    Topics: Aged; Aminolevulinic Acid; Apoptosis; Cells, Cultured; Endoplasmic Reticulum Stress; Epithelial Cell

2015
Lack of hemodynamic effects after extended heme synthesis inhibition by succinylacetone in rats.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 333, Issue:1

    Topics: Aminolevulinic Acid; Animals; Blood Pressure; Guanylate Cyclase; Heme; Hemodynamics; Heptanoates; Hy

2010
Lead induced increase of blood pressure in female lead workers.
    Occupational and environmental medicine, 2002, Volume: 59, Issue:11

    Topics: Adolescent; Adult; Aminolevulinic Acid; Blood Pressure; Confounding Factors, Epidemiologic; Dose-Res

2002
[Influence of lead exposure on arterial hypertension].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 2002, Volume: 55 Suppl 1

    Topics: Adult; Age Factors; Air Pollutants, Occupational; Aminolevulinic Acid; Blood Pressure; Body Mass Ind

2002
Lipids, lipid peroxidation and 7-ketocholesterol in workers exposed to lead.
    Human & experimental toxicology, 2005, Volume: 24, Issue:6

    Topics: Adult; Aminolevulinic Acid; Erythrocytes; Humans; Hypertension; Industry; Ketocholesterols; Lead Poi

2005
Plasma renin activity and urinary kallikrein excretion in lead-exposed workers as related to hypertension and nephropathy.
    Life sciences, 1981, Jan-12, Volume: 28, Issue:2

    Topics: Adult; Aging; Aminolevulinic Acid; Creatinine; Humans; Hypertension; Kallikreins; Kidney Diseases; L

1981
[Lead reassessed as an etiological factor in arterial hypertension].
    Acta medica portuguesa, 1985, Volume: 6, Issue:5

    Topics: Adult; Aminolevulinic Acid; Edetic Acid; Humans; Hypertension; Lead; Lead Poisoning; Male; Middle Ag

1985