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aminolevulinic acid and Benign Cerebellar Neoplasms

aminolevulinic acid has been researched along with Benign Cerebellar Neoplasms in 6 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Research Excerpts

ExcerptRelevanceReference
" Cellular uptake and photodynamic inactivation after incubation with this photosensitizer have neither been examined in medulloblastoma cells in vitro, nor compared with 5-aminolevulinic acid-derived protoporphyrin IX (5-ALA-derived PpIX)."7.78In vitro comparison of hypericin and 5-aminolevulinic acid-derived protoporphyrin IX for photodynamic inactivation of medulloblastoma cells. ( Dietz, K; Noell, S; Ritz, R; Roser, F; Scheidle, C; Schenk, M; Strauss, WS, 2012)
"Hypericin (HYP) is a naturally occurring photosensitizer."5.38In vitro comparison of hypericin and 5-aminolevulinic acid-derived protoporphyrin IX for photodynamic inactivation of medulloblastoma cells. ( Dietz, K; Noell, S; Ritz, R; Roser, F; Scheidle, C; Schenk, M; Strauss, WS, 2012)
"Fluorescence-guided surgery applying 5-aminolevulinic acid (5-ALA) in high-grade gliomas is an established method in adults."4.315-ALA fluorescence in randomly selected pediatric brain tumors assessed by spectroscopy and surgical microscope. ( Haj-Hosseini, N; Hillman, J; Milos, P; Wårdell, K, 2023)
" Cellular uptake and photodynamic inactivation after incubation with this photosensitizer have neither been examined in medulloblastoma cells in vitro, nor compared with 5-aminolevulinic acid-derived protoporphyrin IX (5-ALA-derived PpIX)."3.78In vitro comparison of hypericin and 5-aminolevulinic acid-derived protoporphyrin IX for photodynamic inactivation of medulloblastoma cells. ( Dietz, K; Noell, S; Ritz, R; Roser, F; Scheidle, C; Schenk, M; Strauss, WS, 2012)
"Medulloblastoma is the most common malignant brain tumor in childhood."1.42The use of 5-ALA to assist complete removal of residual non-enhancing part of childhood medulloblastoma: a case report. ( Broholm, H; Bøgeskov, L; Klausen, C; Nysom, K; Sehested, A; Skjøth-Rasmussen, J, 2015)
"Hypericin (HYP) is a naturally occurring photosensitizer."1.38In vitro comparison of hypericin and 5-aminolevulinic acid-derived protoporphyrin IX for photodynamic inactivation of medulloblastoma cells. ( Dietz, K; Noell, S; Ritz, R; Roser, F; Scheidle, C; Schenk, M; Strauss, WS, 2012)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's4 (66.67)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Milos, P1
Haj-Hosseini, N1
Hillman, J1
Wårdell, K1
Della Puppa, A1
Gioffrè, G1
Gardiman, MP1
Frasson, C1
Cecchin, D1
Scienza, R1
Persano, L1
Skjøth-Rasmussen, J1
Bøgeskov, L1
Sehested, A1
Klausen, C1
Broholm, H1
Nysom, K1
Utsuki, S1
Oka, H1
Sato, K1
Shimizu, S1
Suzuki, S1
Fujii, K1
Ritz, R1
Scheidle, C1
Noell, S1
Roser, F1
Schenk, M1
Dietz, K1
Strauss, WS1
Luckers, O1
James, S1
Ghassempour, K1
Maertens de Noordhout, A1
Born, JD1

Other Studies

6 other studies available for aminolevulinic acid and Benign Cerebellar Neoplasms

ArticleYear
5-ALA fluorescence in randomly selected pediatric brain tumors assessed by spectroscopy and surgical microscope.
    Acta neurochirurgica, 2023, Volume: 165, Issue:1

    Topics: Adolescent; Aminolevulinic Acid; Brain Neoplasms; Cerebellar Neoplasms; Child; Child, Preschool; Gli

2023
Intra-operative 5-aminolevulinic acid (ALA)-induced fluorescence of medulloblastoma: phenotypic variability and CD133(+) expression according to different fluorescence patterns.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2014, Volume: 35, Issue:1

    Topics: AC133 Antigen; Aminolevulinic Acid; Antigens, CD; Cerebellar Neoplasms; Fluorescent Dyes; Glycoprote

2014
The use of 5-ALA to assist complete removal of residual non-enhancing part of childhood medulloblastoma: a case report.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2015, Volume: 31, Issue:11

    Topics: Aminolevulinic Acid; Cerebellar Neoplasms; Child; Combined Modality Therapy; Follow-Up Studies; Huma

2015
Fluorescence diagnosis of tumor cells in hemangioblastoma cysts with 5-aminolevulinic acid.
    Journal of neurosurgery, 2010, Volume: 112, Issue:1

    Topics: Adult; Aminolevulinic Acid; Central Nervous System Cysts; Cerebellar Neoplasms; Female; Fluorescence

2010
In vitro comparison of hypericin and 5-aminolevulinic acid-derived protoporphyrin IX for photodynamic inactivation of medulloblastoma cells.
    PloS one, 2012, Volume: 7, Issue:12

    Topics: Aminolevulinic Acid; Anthracenes; Cell Line, Tumor; Cerebellar Neoplasms; Humans; Medulloblastoma; M

2012
[Image of the month. 5-aminolevulinic acid (5-ALA) in the guided treatment of malignant brain tumors].
    Revue medicale de Liege, 2008, Volume: 63, Issue:1

    Topics: Aged; Aminolevulinic Acid; Cerebellar Neoplasms; Fluorescent Dyes; Glioblastoma; Humans; Male; Neuro

2008