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aminolevulinic acid and Barrett Epithelium

aminolevulinic acid has been researched along with Barrett Epithelium in 61 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Research Excerpts

ExcerptRelevanceReference
"The percentage regression of Barrett esophagus, as well as the recurrence rate of HGD/EC, was calculated."5.33Poor results of 5-aminolevulinic acid-photodynamic therapy for residual high-grade dysplasia and early cancer in barrett esophagus after endoscopic resection. ( Aalders, M; Bergman, J; Fockens, P; Kara, M; Krishnadath, K; Peters, F; Rosmolen, W; Ten Kate, F; van Lanschot, J, 2005)
"All patients had residual Barrett esophagus after PDT; the median regression percentage was 50 % (IQR 25 - 70 %)."5.33Poor results of 5-aminolevulinic acid-photodynamic therapy for residual high-grade dysplasia and early cancer in barrett esophagus after endoscopic resection. ( Aalders, M; Bergman, J; Fockens, P; Kara, M; Krishnadath, K; Peters, F; Rosmolen, W; Ten Kate, F; van Lanschot, J, 2005)
"Surveillance of patients with Barrett's esophagus or ulcerative colitis for dysplasia is confined to biopsy specimens taken randomly during endoscopy because dysplasia remains undetectable by visual inspection."5.30Endoscopic fluorescence detection of dysplasia in patients with Barrett's esophagus, ulcerative colitis, or adenomatous polyps after 5-aminolevulinic acid-induced protoporphyrin IX sensitization. ( Bäumler, W; Holstege, A; Knüchel, R; Messmann, H; Schölmerich, J, 1999)
"Eleven patients with high-grade mucosal dysplasia in a columnar-lined oesophagus and 2 patients with a squamous carcinoma (uT1) underwent photodynamic therapy (PDT) and argon-plasma coagulation (APC)."3.70[Photodynamic ablation and argon-plasma coagulation of premalignant and early-stage malignant lesions of the oesophagus--an alternative to surgery?]. ( Beger, HG; Orth, K; Rück, A; Russ, D; Stanescu, A, 1999)
" The aim of this study was to establish the optimum dosage regime for ALA-PDT for Barrett's esophagus."2.71Comparison of high- vs low-dose 5-aminolevulinic acid for photodynamic therapy of Barrett's esophagus. ( Ackroyd, R; Brown, NJ; Brown, SB; Kelty, CJ; Reed, MW, 2004)
" There was no significant difference in response between dosing 4 or 6 h prior to PDT."2.71Comparison of high- vs low-dose 5-aminolevulinic acid for photodynamic therapy of Barrett's esophagus. ( Ackroyd, R; Brown, NJ; Brown, SB; Kelty, CJ; Reed, MW, 2004)
"Twenty-five patients with Barrett's esophagus were randomized to receive 30 (low-dose) or 60 (high-dose) mg/kg oral ALA at 4 or 6 h or 30 mg/kg in two fractions 4 and 6 h before PDT."2.71Comparison of high- vs low-dose 5-aminolevulinic acid for photodynamic therapy of Barrett's esophagus. ( Ackroyd, R; Brown, NJ; Brown, SB; Kelty, CJ; Reed, MW, 2004)
"Barrett's esophagus is the major risk factor for esophageal adenocarcinoma, the incidence of which is increasing rapidly in the Western world."2.71Comparison of high- vs low-dose 5-aminolevulinic acid for photodynamic therapy of Barrett's esophagus. ( Ackroyd, R; Brown, NJ; Brown, SB; Kelty, CJ; Reed, MW, 2004)
" This study demonstrates that ALA-induced PDT provides safe and effective ablation therapy for Barrett's esophagus and is particularly useful against dysplasia."2.69Aminolevulinic acid-induced photodynamic therapy: safe and effective ablation of dysplasia in Barrett's esophagus. ( Ackroyd, R; Brown, NJ; Davis, MF; Reed, MW; Stephenson, TJ; Stoddard, CJ, 2000)
"Forty patients with dysplastic Barrett's esophagus were given aminolevulinic acid (ALA) 30 mg/kg orally followed 4 h later by laser endoscopy."2.69Aminolevulinic acid-induced photodynamic therapy: safe and effective ablation of dysplasia in Barrett's esophagus. ( Ackroyd, R; Brown, NJ; Davis, MF; Reed, MW; Stephenson, TJ; Stoddard, CJ, 2000)
"Surveillance of Barrett's esophagus is routinely undertaken to detect early malignant transformation."2.425-Aminolaevulinic acid-induced photodynamic therapy and photodetection in Barrett's esophagus. ( Ackroyd, R; Claydon, PE, 2004)
"Barrett's esophagus is a precursor of adenocarcinoma of the esophagus."2.425-Aminolaevulinic acid-induced photodynamic therapy and photodetection in Barrett's esophagus. ( Ackroyd, R; Claydon, PE, 2004)
"Barrett's esophagus is the major risk factor for the development of esophageal adenocarcinoma, which is increasing in incidence faster than any other cancer in the Western world."2.41Photodynamic therapy for Barrett's esophagus: a review. ( Ackroyd, R; Kelty, CJ; Marcus, SL, 2002)
"Barrett's esophagus has previously been considered an irreversible lesion that required life-long surveillance to detect malignant transformation."2.41Photodynamic therapy for Barrett's esophagus: a review. ( Ackroyd, R; Kelty, CJ; Marcus, SL, 2002)
"Barrett's esophagus has been identified as the premalignant precursor of esophageal adenocarcinoma."2.41Barrett's esophagus: treatment with 5-aminolevulinic acid photodynamic therapy. ( Barr, H, 2000)
"The percentage regression of Barrett esophagus, as well as the recurrence rate of HGD/EC, was calculated."1.33Poor results of 5-aminolevulinic acid-photodynamic therapy for residual high-grade dysplasia and early cancer in barrett esophagus after endoscopic resection. ( Aalders, M; Bergman, J; Fockens, P; Kara, M; Krishnadath, K; Peters, F; Rosmolen, W; Ten Kate, F; van Lanschot, J, 2005)
"All patients had residual Barrett esophagus after PDT; the median regression percentage was 50 % (IQR 25 - 70 %)."1.33Poor results of 5-aminolevulinic acid-photodynamic therapy for residual high-grade dysplasia and early cancer in barrett esophagus after endoscopic resection. ( Aalders, M; Bergman, J; Fockens, P; Kara, M; Krishnadath, K; Peters, F; Rosmolen, W; Ten Kate, F; van Lanschot, J, 2005)
"Barrett's esophagus is strongly associated with adenocarcinoma."1.32Endoscopic fluorescence detection of intraepithelial neoplasia in Barrett's esophagus after oral administration of aminolevulinic acid. ( Dorta, G; Felley, C; Fontolliet, C; Gabrecht, T; Grosjean, P; Jornod, P; Lange, N; Monnier, P; Stepinac, T; van den Bergh, H; vanMelle, G; Wagnières, G, 2003)
"14 patients with histologically proven Barrett's esophagus, seven of whom had evidence of low-grade dysplasia, underwent endoscopic treatment with topical delta-ALA."1.31Is topical delta-aminolevulinic acid adequate for photodynamic therapy in Barrett's esophagus? A pilot study. ( Dietel, M; Ebert, B; Fleige, B; Liebetruth, J; Lochs, H; Ortner, M-; Zumbusch, K, 2002)
"Barrett's esophagus is a complication of gastroesophageal reflux disease (GERD) characterized by specialized columnar epithelium that contains goblet cells and replaces the squamous epithelium of the distal esophagus."1.31[Endoscopic fluorescence diagnosis of esophageal carcinoma after sensitization with 5-aminolevulinic acid]. ( Endlicher, E; Fürst, A; Knüchel, R; Messmann, H; Schölmerich, J, 2001)
"Eight patients with Barrett's esophagus and/or early cancer were treated."1.31[Photodynamic therapy of dysplasias and early carcinomas in Barrett esophagus with a diode laser system--a pilot study]. ( Apel, D; Arnold, JC; Jakobs, R; Riemann, JF; Rosenbaum, A; Zöpf, T, 2001)
"Surveillance of patients with Barrett's esophagus or ulcerative colitis for dysplasia is confined to biopsy specimens taken randomly during endoscopy because dysplasia remains undetectable by visual inspection."1.30Endoscopic fluorescence detection of dysplasia in patients with Barrett's esophagus, ulcerative colitis, or adenomatous polyps after 5-aminolevulinic acid-induced protoporphyrin IX sensitization. ( Bäumler, W; Holstege, A; Knüchel, R; Messmann, H; Schölmerich, J, 1999)
"PDT of Barrett's esophagus with severe dysplasia, or of mucosal carcinomas and superficial squamous-cell cancer of the esophagus, requires light application devices allowing homogeneous illumination of the tissue surface in spite of esophageal motility and respiratory movement."1.30A new long-range through-the-scope balloon applicator for photodynamic therapy in the esophagus and cardia. ( Ell, C; Gossner, L; May, A; Sroka, R, 1999)

Research

Studies (61)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's16 (26.23)18.2507
2000's37 (60.66)29.6817
2010's7 (11.48)24.3611
2020's1 (1.64)2.80

Authors

AuthorsStudies
Grosenick, D1
Bremer, C1
Kohoutova, D1
Haidry, R2
Banks, M1
Butt, MA1
Dunn, J2
Thorpe, S2
Lovat, L2
Yeh, SC2
Ling, CS1
Andrews, DW2
Patterson, MS2
Diamond, KR1
Hayward, JE1
Armstrong, D2
Fang, Q2
Sahli, S1
Provias, J1
Holz, JA1
Boerwinkel, DF1
Meijer, SL1
Visser, M1
van Leeuwen, TG1
Bergman, JJ1
Aalders, MC2
Mackenzie, GD3
Dunn, JM2
Selvasekar, CR1
Mosse, CA3
Thorpe, SM2
Novelli, MR3
Bown, SG3
Lovat, LB3
Gross, SA1
Wolfsen, HC2
Davila, ML1
Banks, MR1
Green, S1
Rodriguez-Justo, M1
Winstanley, A1
Ortner, M-1
Zumbusch, K2
Liebetruth, J1
Ebert, B2
Fleige, B2
Dietel, M2
Lochs, H3
Hinnen, P4
de Rooij, FW5
Hop, WC1
Edixhoven, A4
van Dekken, H3
Wilson, JH4
Siersema, PD8
Kelty, CJ5
Marcus, SL2
Ackroyd, R9
Brand, S1
Wang, TD1
Schomacker, KT1
Poneros, JM1
Lauwers, GY1
Compton, CC1
Pedrosa, MC1
Nishioka, NS1
van Veen, RL2
Pasma, KL1
Haringsma, J2
van de Vrie, W2
Gabeler, EE1
Robinson, DJ1
Sterenborg, HJ2
Ortner, MA1
Hein, E1
Nolte, D1
Sukowski, U1
Weber-Eibel, J1
Stolte, M3
Oberhuber, G1
Porschen, R1
Klump, B1
Hörtnagl, H1
Rinneberg, H1
Brown, NJ6
Stephenson, TJ4
Stoddard, CJ4
Reed, MW6
Stepinac, T1
Felley, C1
Jornod, P1
Lange, N2
Gabrecht, T1
Fontolliet, C1
Grosjean, P1
vanMelle, G1
van den Bergh, H1
Monnier, P1
Wagnières, G1
Dorta, G1
Prosst, RL1
Gahlen, J1
Brown, SB1
Van Laethem, JL2
Devière, J1
Hage, M1
Steyerberg, EW1
Grool, TE1
Kuipers, EJ1
Claydon, PE1
Sylantiev, C1
Schoenfeld, N1
Mamet, R1
Groozman, GB1
Drory, VE1
Peters, F1
Kara, M1
Rosmolen, W1
Aalders, M1
Ten Kate, F1
Krishnadath, K1
van Lanschot, J1
Fockens, P1
Bergman, J1
Pech, O2
Gossner, L4
May, A4
Rabenstein, T1
Vieth, M1
Berres, M1
Ell, C4
Abbas, G1
Pennathur, A1
Keeley, SB1
Landreneau, RJ1
Luketich, JD1
Globe, J1
Smythe, A1
Jamieson, NF1
Clark, BR1
Collaud, S1
Warloe, T1
Jordan, O1
Gurny, R1
Kelley, DJ1
Shah, JP1
Barr, H2
Shepherd, NA1
Dix, A1
Roberts, DJ1
Tan, WC1
Krasner, N1
Heller, SJ1
Van Dam, J1
Vonarx, V1
Eleouet, S1
Carre, J1
Ioss, P1
Gouyette, A1
Leray, AM1
Merle, C1
Lajat, Y2
Patrice, T2
Sroka, R2
Rick, K1
Hahn, EG1
Ortner, M1
Messmann, H5
Knüchel, R3
Endlicher, E3
Hauser, T2
Szeimies, RM2
Kullmann, F1
Bäumler, W2
Schölmerich, J4
van Velthuysen, ML1
van Hillegersberg, R4
Tilanus, HW2
Holstege, A1
van den Boogert, J2
Houtsmuller, AB1
de Bruin, RW2
Wang, KK2
Fennerty, MB1
Orth, K1
Stanescu, A1
Rück, A1
Russ, D1
Beger, HG1
Keller, R1
Fischbach, W1
Brown, N1
Vernon, D1
Roberts, D1
Stephenson, T1
Marcus, S1
Stoddard, C1
Reed, M1
Terlouw, EM1
Davis, MF2
Johnson, AG1
Knuechel, R1
Fürst, A1
Zöpf, T1
Rosenbaum, A1
Apel, D1
Jakobs, R1
Arnold, JC1
Riemann, JF1
van Staveren, HJ1
Eisendrath, P1
Bourre, L1
Thibaut, S1
Briffaud, A1
Nagy, CD1

Reviews

12 reviews available for aminolevulinic acid and Barrett Epithelium

ArticleYear
Fluorescence Imaging of Breast Tumors and Gastrointestinal Cancer.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 2020, Volume: 216

    Topics: Aminolevulinic Acid; Barrett Esophagus; Breast Neoplasms; Female; Fluorescence; Gastrointestinal Neo

2020
The role of photodynamic therapy in the esophagus.
    Gastrointestinal endoscopy clinics of North America, 2010, Volume: 20, Issue:1

    Topics: Adenocarcinoma; Aminolevulinic Acid; Barrett Esophagus; Dihematoporphyrin Ether; Esophageal Neoplasm

2010
Photodynamic therapy.
    Gastrointestinal endoscopy clinics of North America, 2011, Volume: 21, Issue:1

    Topics: Adenocarcinoma; Aminolevulinic Acid; Barrett Esophagus; Dihematoporphyrin Ether; Esophageal Neoplasm

2011
Photodynamic therapy for Barrett's esophagus: a review.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2002, Volume: 15, Issue:2

    Topics: Aminolevulinic Acid; Antineoplastic Agents; Barrett Esophagus; Dihematoporphyrin Ether; Hematoporphy

2002
Photodynamic therapy for esophageal diseases: a clinical update.
    Endoscopy, 2003, Volume: 35, Issue:12

    Topics: Adenocarcinoma; Aminolevulinic Acid; Barrett Esophagus; Dihematoporphyrin Ether; Endosonography; Eso

2003
5-Aminolaevulinic acid-induced photodynamic therapy and photodetection in Barrett's esophagus.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2004, Volume: 17, Issue:3

    Topics: Adenocarcinoma; Aminolevulinic Acid; Barrett Esophagus; Clinical Trials as Topic; Esophageal Neoplas

2004
Laser ablation therapies for Barrett's esophagus.
    Seminars in thoracic and cardiovascular surgery, 2005,Winter, Volume: 17, Issue:4

    Topics: Aminolevulinic Acid; Argon; Barrett Esophagus; Dihematoporphyrin Ether; Humans; Laser Therapy; Photo

2005
Photodynamic therapy using 5-aminolaevulinic acid for the treatment of dysplasia in Barrett's oesophagus.
    Expert opinion on pharmacotherapy, 2008, Volume: 9, Issue:5

    Topics: Administration, Oral; Aminolevulinic Acid; Animals; Barrett Esophagus; Controlled Clinical Trials as

2008
Current status of photodynamic therapy of Barrett's esophagus.
    Gastrointestinal endoscopy, 1999, Volume: 49, Issue:3 Pt 2

    Topics: Aminolevulinic Acid; Barrett Esophagus; Dihematoporphyrin Ether; Epithelium; Esophageal Neoplasms; H

1999
[Fluorescence endoscopy in gastroenterology].
    Zeitschrift fur Gastroenterologie, 2000, Volume: 38, Issue:1

    Topics: Aminolevulinic Acid; Barrett Esophagus; Colitis, Ulcerative; Colonic Neoplasms; Endoscopy, Gastroint

2000
Barrett's esophagus: treatment with 5-aminolevulinic acid photodynamic therapy.
    Gastrointestinal endoscopy clinics of North America, 2000, Volume: 10, Issue:3

    Topics: Aminolevulinic Acid; Barrett Esophagus; Esophagoscopy; Humans; Injections, Intravenous; Intestinal M

2000
Photodynamic therapy of Barrett's esophagus.
    Gastrointestinal endoscopy clinics of North America, 2000, Volume: 10, Issue:3

    Topics: Aminolevulinic Acid; Barrett Esophagus; Esophagoscopy; Fiber Optic Technology; Hematoporphyrin Deriv

2000

Trials

12 trials available for aminolevulinic acid and Barrett Epithelium

ArticleYear
Long-term outcomes of the randomized controlled trial comparing 5-aminolaevulinic acid and Photofrin photodynamic therapy for Barrett's oesophagus related neoplasia.
    Scandinavian journal of gastroenterology, 2018, Volume: 53, Issue:5

    Topics: Adenocarcinoma; Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Catheter Ablation; Dihematoporp

2018
Optimal conditions for successful ablation of high-grade dysplasia in Barrett's oesophagus using aminolaevulinic acid photodynamic therapy.
    Lasers in medical science, 2009, Volume: 24, Issue:5

    Topics: Aminolevulinic Acid; Barrett Esophagus; Esophagus; Humans; Kaplan-Meier Estimate; Lasers; Optical Ph

2009
A randomised controlled trial of ALA vs. Photofrin photodynamic therapy for high-grade dysplasia arising in Barrett's oesophagus.
    Lasers in medical science, 2013, Volume: 28, Issue:3

    Topics: Adenocarcinoma; Aged; Aminolevulinic Acid; Barrett Esophagus; Dihematoporphyrin Ether; Disease Progr

2013
Timing of 5-aminolaevulinic acid-induced photodynamic therapy for the treatment of patients with Barrett's oesophagus.
    Journal of photochemistry and photobiology. B, Biology, 2002, Volume: 68, Issue:1

    Topics: Administration, Oral; Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Biopsy; Endoscopy; Female

2002
In situ light dosimetry during photodynamic therapy of Barrett's esophagus with 5-aminolevulinic acid.
    Lasers in surgery and medicine, 2002, Volume: 31, Issue:5

    Topics: Aminolevulinic Acid; Barrett Esophagus; Esophagus; Humans; Light; Photochemotherapy; Photosensitizin

2002
Comparison of high- vs low-dose 5-aminolevulinic acid for photodynamic therapy of Barrett's esophagus.
    Surgical endoscopy, 2004, Volume: 18, Issue:3

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Cohort

2004
5-aminolevulinic acid photodynamic therapy versus argon plasma coagulation for ablation of Barrett's oesophagus: a randomised trial.
    Gut, 2004, Volume: 53, Issue:6

    Topics: Aged; Aminolevulinic Acid; Barrett Esophagus; Esophagoscopy; Female; Follow-Up Studies; Humans; Lase

2004
Endoscopic ablation of Barrett's oesophagus: a randomized-controlled trial of photodynamic therapy vs. argon plasma coagulation.
    Alimentary pharmacology & therapeutics, 2004, Volume: 20, Issue:11-12

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Esophagoscopy; Female; Follo

2004
Clinical evaluation of bioadhesive hydrogels for topical delivery of hexylaminolevulinate to Barrett's esophagus.
    Journal of controlled release : official journal of the Controlled Release Society, 2007, Nov-20, Volume: 123, Issue:3

    Topics: Acrylic Resins; Adhesiveness; Administration, Oral; Administration, Topical; Adult; Aminolevulinic A

2007
5-Aminolevulinic acid photosensitization of dysplastic Barrett's esophagus: a pharmacokinetic study.
    Photochemistry and photobiology, 1999, Volume: 70, Issue:4

    Topics: Aminolevulinic Acid; Barrett Esophagus; Humans; Photochemotherapy; Photosensitizing Agents; Protopor

1999
Aminolevulinic acid-induced photodynamic therapy: safe and effective ablation of dysplasia in Barrett's esophagus.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2000, Volume: 13, Issue:1

    Topics: Aminolevulinic Acid; Barrett Esophagus; Follow-Up Studies; Humans; Photochemotherapy; Photosensitizi

2000
Photodynamic therapy for dysplastic Barrett's oesophagus: a prospective, double blind, randomised, placebo controlled trial.
    Gut, 2000, Volume: 47, Issue:5

    Topics: Adult; Aged; Aminolevulinic Acid; Anti-Ulcer Agents; Barrett Esophagus; Double-Blind Method; Drug Th

2000

Other Studies

37 other studies available for aminolevulinic acid and Barrett Epithelium

ArticleYear
5-aminolevulinic acid for quantitative seek-and-treat of high-grade dysplasia in Barrett's esophagus cellular models.
    Journal of biomedical optics, 2015, Volume: 20, Issue:2

    Topics: Aminolevulinic Acid; Barrett Esophagus; Cell Line, Tumor; Cell Survival; Humans; Intracellular Space

2015
5-Aminolevulinic acid induced protoporphyrin IX as a fluorescence marker for quantitative image analysis of high-grade dysplasia in Barrett's esophagus cellular models.
    Journal of biomedical optics, 2015, Volume: 20, Issue:3

    Topics: Adenocarcinoma; Algorithms; Aminolevulinic Acid; Barrett Esophagus; Biomarkers; Esophageal Neoplasms

2015
Fluorescence characteristics of human Barrett tissue specimens grafted on chick chorioallantoic membrane.
    Lasers in medical science, 2016, Volume: 31, Issue:1

    Topics: Aminolevulinic Acid; Animals; Barrett Esophagus; Biopsy; Chickens; Chorioallantoic Membrane; Humans;

2016
Is topical delta-aminolevulinic acid adequate for photodynamic therapy in Barrett's esophagus? A pilot study.
    Endoscopy, 2002, Volume: 34, Issue:8

    Topics: Aminolevulinic Acid; Barrett Esophagus; Esophageal Neoplasms; Female; Humans; Male; Middle Aged; Pho

2002
Detection of high-grade dysplasia in Barrett's esophagus by spectroscopy measurement of 5-aminolevulinic acid-induced protoporphyrin IX fluorescence.
    Gastrointestinal endoscopy, 2002, Volume: 56, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Esophageal Neoplasms; Esopha

2002
Time gated fluorescence spectroscopy in Barrett's oesophagus.
    Gut, 2003, Volume: 52, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Biomarkers,

2003
Two course illuminating scheme improves aminolevulinic acid photodynamic therapy in cell cultures.
    Cellular and molecular biology (Noisy-le-Grand, France), 2002, Volume: 48, Issue:8

    Topics: Aminolevulinic Acid; Barrett Esophagus; Cell Line, Transformed; Cells, Cultured; Ferrochelatase; Hum

2002
Eradication of dysplastic Barrett's oesophagus using photodynamic therapy: long-term follow-up.
    Endoscopy, 2003, Volume: 35, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Anti-Ulcer Agents; Barrett Esophagus; Esophagos

2003
Endoscopic fluorescence detection of intraepithelial neoplasia in Barrett's esophagus after oral administration of aminolevulinic acid.
    Endoscopy, 2003, Volume: 35, Issue:8

    Topics: Administration, Oral; Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Carcinoma in Situ; Esopha

2003
Endoscopic therapy of Barrett's: what more do we need to know?
    Gut, 2004, Volume: 53, Issue:6

    Topics: Aminolevulinic Acid; Barrett Esophagus; Esophagoscopy; Humans; Photochemotherapy; Photosensitizing A

2004
Acute neuropathy mimicking porphyria induced by aminolevulinic acid during photodynamic therapy.
    Muscle & nerve, 2005, Volume: 31, Issue:3

    Topics: Acute Disease; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Diagnosis, Different

2005
Poor results of 5-aminolevulinic acid-photodynamic therapy for residual high-grade dysplasia and early cancer in barrett esophagus after endoscopic resection.
    Endoscopy, 2005, Volume: 37, Issue:5

    Topics: Aged; Aminolevulinic Acid; Barrett Esophagus; Chemotherapy, Adjuvant; Cohort Studies; Esophagoscopy;

2005
Long-term results of photodynamic therapy with 5-aminolevulinic acid for superficial Barrett's cancer and high-grade intraepithelial neoplasia.
    Gastrointestinal endoscopy, 2005, Volume: 62, Issue:1

    Topics: Adenocarcinoma; Aged; Aminolevulinic Acid; Barrett Esophagus; Disease-Free Survival; Esophageal Neop

2005
The effect of photodynamic therapy (PDT) on oesophageal motility and acid clearance in patients with Barrett's oesophagus.
    Journal of photochemistry and photobiology. B, Biology, 2006, Oct-02, Volume: 85, Issue:1

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Female; Gastric Acid; Humans; Hydro

2006
How light dosimetry influences the efficacy of photodynamic therapy with 5-aminolaevulinic acid for ablation of high-grade dysplasia in Barrett's esophagus.
    Lasers in medical science, 2008, Volume: 23, Issue:2

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Dose-Response Relationship, Radiati

2008
Management of Barrett's oesophagus.
    Lancet (London, England), 1996, Aug-31, Volume: 348, Issue:9027

    Topics: Aminolevulinic Acid; Barrett Esophagus; Humans; Photochemotherapy; Proton Pump Inhibitors

1996
Eradication of high-grade dysplasia in columnar-lined (Barrett's) oesophagus by photodynamic therapy with endogenously generated protoporphyrin IX.
    Lancet (London, England), 1996, Aug-31, Volume: 348, Issue:9027

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Humans; Male; Middle Aged; Photoche

1996
Eradication of high-grade dysplasia using 5-ALA and acid suppression: a (photo)dynamic duo.
    Gastroenterology, 1997, Volume: 112, Issue:6

    Topics: Aminolevulinic Acid; Barrett Esophagus; Gastric Acid; Humans

1997
Potential efficacy of a delta 5-aminolevulinic acid bioadhesive gel formulation for the photodynamic treatment of lesions of the gastrointestinal tract in mice.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:7

    Topics: Aminolevulinic Acid; Animals; Barrett Esophagus; Biocompatible Materials; Disease Models, Animal; Fi

1997
Photodynamic ablation of high-grade dysplasia and early cancer in Barrett's esophagus by means of 5-aminolevulinic acid.
    Gastroenterology, 1998, Volume: 114, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Esophageal Neoplasms; Female

1998
[Eradication of high-grade dysplasia in Barrett esophagus by photodynamic therapy with endogenously generated protoporphyrin IX].
    Zeitschrift fur Gastroenterologie, 1998, Volume: 36, Issue:1

    Topics: Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Esophageal Neoplasms; Esophagus; Fe

1998
[Photodynamic diagnosis of gastrointestinal precancerous lesions after sensitization with 5-aminolevulinic acid. A pilot study].
    Deutsche medizinische Wochenschrift (1946), 1998, Apr-24, Volume: 123, Issue:17

    Topics: Adenoma; Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Colitis, Ulcerative; Colorectal Neopla

1998
Biochemical basis of 5-aminolaevulinic acid-induced protoporphyrin IX accumulation: a study in patients with (pre)malignant lesions of the oesophagus.
    British journal of cancer, 1998, Volume: 78, Issue:5

    Topics: Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Esophageal Neoplasms; Esophagus; Female; Ferroc

1998
Endoscopic fluorescence detection of dysplasia in patients with Barrett's esophagus, ulcerative colitis, or adenomatous polyps after 5-aminolevulinic acid-induced protoporphyrin IX sensitization.
    Gastrointestinal endoscopy, 1999, Volume: 49, Issue:1

    Topics: Adenomatous Polyps; Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Biopsy; Colitis, Ulcerative

1999
Kinetics, localization, and mechanism of 5-aminolevulinic acid-induced porphyrin accumulation in normal and Barrett's-like rat esophagus.
    Lasers in surgery and medicine, 1999, Volume: 24, Issue:1

    Topics: Administration, Oral; Aminolevulinic Acid; Animals; Barrett Esophagus; Disease Models, Animal; Esoph

1999
Perspectives on endoscopic eradication of Barrett's esophagus: who are appropriate candidates and what is the best method?
    Gastrointestinal endoscopy, 1999, Volume: 49, Issue:3 Pt 2

    Topics: Aminolevulinic Acid; Barrett Esophagus; Biopsy; Electrocoagulation; Endoscopy; Endoscopy, Gastrointe

1999
[Photodynamic ablation and argon-plasma coagulation of premalignant and early-stage malignant lesions of the oesophagus--an alternative to surgery?].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1999, Volume: 70, Issue:4

    Topics: Aged; Aminolevulinic Acid; Argon; Barrett Esophagus; Carcinoma; Esophageal Neoplasms; Female; Humans

1999
A new long-range through-the-scope balloon applicator for photodynamic therapy in the esophagus and cardia.
    Endoscopy, 1999, Volume: 31, Issue:5

    Topics: Adenocarcinoma; Aged; Aminolevulinic Acid; Barrett Esophagus; Biopsy; Carcinoma, Squamous Cell; Card

1999
[Endoscopic fluorescence detection of dysplasia in patients with Barrett's esophagus, ulcerative colitis or colorectal adenomas].
    Zeitschrift fur Gastroenterologie, 1999, Volume: 37, Issue:8

    Topics: Adenomatous Polyps; Aminolevulinic Acid; Barrett Esophagus; Biopsy; Colitis, Ulcerative; Colorectal

1999
Porphyrin biosynthesis in human Barrett's oesophagus and adenocarcinoma after ingestion of 5-aminolaevulinic acid.
    British journal of cancer, 2000, Volume: 83, Issue:4

    Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett E

2000
Endoscopic fluorescence detection of low and high grade dysplasia in Barrett's oesophagus using systemic or local 5-aminolaevulinic acid sensitisation.
    Gut, 2001, Volume: 48, Issue:3

    Topics: Administration, Oral; Administration, Topical; Aminolevulinic Acid; Barrett Esophagus; Biopsy; Esoph

2001
[Endoscopic fluorescence diagnosis of esophageal carcinoma after sensitization with 5-aminolevulinic acid].
    Medizinische Klinik (Munich, Germany : 1983), 2001, Mar-15, Volume: 96, Issue:3

    Topics: Adenocarcinoma; Aminolevulinic Acid; Barrett Esophagus; Diagnosis, Differential; Esophageal Neoplasm

2001
[Photodynamic therapy of dysplasias and early carcinomas in Barrett esophagus with a diode laser system--a pilot study].
    Medizinische Klinik (Munich, Germany : 1983), 2001, Apr-15, Volume: 96, Issue:4

    Topics: Adenocarcinoma; Aged; Aminolevulinic Acid; Barrett Esophagus; Cell Transformation, Neoplastic; Esoph

2001
Fractionated illumination for oesophageal ALA-PDT: effect on blood flow and PpIX formation.
    Lasers in medical science, 2001, Volume: 16, Issue:1

    Topics: Aminolevulinic Acid; Animals; Barrett Esophagus; Esophagus; Male; Photochemotherapy; Protoporphyrins

2001
Endoscopic fluorescence detection of low and high grade dysplasia in Barrett's oesophagus using systemic or local 5-aminolaevulinic acid sensitization.
    Gastrointestinal endoscopy, 2002, Volume: 55, Issue:2

    Topics: Administration, Oral; Administration, Topical; Aminolevulinic Acid; Barrett Esophagus; Cell Transfor

2002
Potential efficacy of a delta 5-aminolevulinic acid thermosetting gel formulation for use in photodynamic therapy of lesions of the gastrointestinal tract.
    Pharmacological research, 2002, Volume: 45, Issue:2

    Topics: Aminolevulinic Acid; Animals; Barrett Esophagus; Drug Stability; Gastric Mucosa; Gels; Male; Mice; M

2002
Photodynamic therapy of human Barrett's cancer using 5-aminolaevulinic acid-induced protoporphyrin IX: an in-vivo dosimetry study in athymic nude mice.
    European journal of gastroenterology & hepatology, 2002, Volume: 14, Issue:6

    Topics: Adenocarcinoma; Aminolevulinic Acid; Animals; Barrett Esophagus; Esophageal Neoplasms; Humans; Mice;

2002