aminolevulinic acid has been researched along with Arachnoidal Cerebellar Sarcoma, Circumscribed in 9 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Cellular uptake and photodynamic inactivation after incubation with this photosensitizer have neither been examined in medulloblastoma cells in vitro, nor compared with 5-aminolevulinic acid-derived protoporphyrin IX (5-ALA-derived PpIX)." | 7.78 | In vitro comparison of hypericin and 5-aminolevulinic acid-derived protoporphyrin IX for photodynamic inactivation of medulloblastoma cells. ( Dietz, K; Noell, S; Ritz, R; Roser, F; Scheidle, C; Schenk, M; Strauss, WS, 2012) |
| "Hypericin (HYP) is a naturally occurring photosensitizer." | 5.38 | In vitro comparison of hypericin and 5-aminolevulinic acid-derived protoporphyrin IX for photodynamic inactivation of medulloblastoma cells. ( Dietz, K; Noell, S; Ritz, R; Roser, F; Scheidle, C; Schenk, M; Strauss, WS, 2012) |
| "5-aminolevulinic acid (5-ALA) has been used for the last 5 years to increase the extent of resection in adult brain tumors, mostly glioblastomas, but it is not approved yet as standard adjuvant treatment in the pediatric population." | 4.90 | 5-ALA fluorescence-assisted surgery in pediatric brain tumors: report of three cases and review of the literature. ( Albanese, V; Barbagallo, GM; Certo, F; Heiss, K, 2014) |
| " Cellular uptake and photodynamic inactivation after incubation with this photosensitizer have neither been examined in medulloblastoma cells in vitro, nor compared with 5-aminolevulinic acid-derived protoporphyrin IX (5-ALA-derived PpIX)." | 3.78 | In vitro comparison of hypericin and 5-aminolevulinic acid-derived protoporphyrin IX for photodynamic inactivation of medulloblastoma cells. ( Dietz, K; Noell, S; Ritz, R; Roser, F; Scheidle, C; Schenk, M; Strauss, WS, 2012) |
| "5-aminolevulinic acid (5-ALA) has been used for the last 5 years to increase the extent of resection in adult brain tumors, mostly glioblastomas, but it is not approved yet as standard adjuvant treatment in the pediatric population." | 2.50 | 5-ALA fluorescence-assisted surgery in pediatric brain tumors: report of three cases and review of the literature. ( Albanese, V; Barbagallo, GM; Certo, F; Heiss, K, 2014) |
| "Medulloblastoma is the most common malignant brain tumor in childhood." | 1.42 | The use of 5-ALA to assist complete removal of residual non-enhancing part of childhood medulloblastoma: a case report. ( Broholm, H; Bøgeskov, L; Klausen, C; Nysom, K; Sehested, A; Skjøth-Rasmussen, J, 2015) |
| "Histology revealed pilocytic astrocytoma (n = 7), classical medulloblastoma (n = 4), anaplastic astrocytoma (n = 1), glioblastoma (n = 3) and anaplastic ependymoma (n = 1)." | 1.40 | Fluorescence-guided surgery with 5-aminolevulinic acid for resection of brain tumors in children--a technical report. ( Beez, T; Hänggi, D; Sarikaya-Seiwert, S; Steiger, HJ, 2014) |
| "Hypericin (HYP) is a naturally occurring photosensitizer." | 1.38 | In vitro comparison of hypericin and 5-aminolevulinic acid-derived protoporphyrin IX for photodynamic inactivation of medulloblastoma cells. ( Dietz, K; Noell, S; Ritz, R; Roser, F; Scheidle, C; Schenk, M; Strauss, WS, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (88.89) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Labuschagne, JJ | 1 |
| Briel-Pump, A | 1 |
| Beez, T | 2 |
| Ebbert, L | 1 |
| Remke, M | 1 |
| Weinhold, S | 1 |
| Sabel, MC | 1 |
| Sorg, RV | 1 |
| Della Puppa, A | 1 |
| Gioffrè, G | 1 |
| Gardiman, MP | 1 |
| Frasson, C | 1 |
| Cecchin, D | 1 |
| Scienza, R | 1 |
| Persano, L | 1 |
| Sarikaya-Seiwert, S | 2 |
| Steiger, HJ | 2 |
| Hänggi, D | 1 |
| Schwake, M | 1 |
| Günes, D | 1 |
| Köchling, M | 1 |
| Brentrup, A | 1 |
| Schroeteler, J | 1 |
| Hotfilder, M | 1 |
| Fruehwald, MC | 1 |
| Stummer, W | 2 |
| Ewelt, C | 1 |
| Barbagallo, GM | 1 |
| Certo, F | 1 |
| Heiss, K | 1 |
| Albanese, V | 1 |
| Skjøth-Rasmussen, J | 1 |
| Bøgeskov, L | 1 |
| Sehested, A | 1 |
| Klausen, C | 1 |
| Broholm, H | 1 |
| Nysom, K | 1 |
| Eicker, S | 1 |
| Borkhardt, A | 1 |
| Gierga, K | 1 |
| Turowski, B | 1 |
| Heiroth, HJ | 1 |
| Ritz, R | 1 |
| Scheidle, C | 1 |
| Noell, S | 1 |
| Roser, F | 1 |
| Schenk, M | 1 |
| Dietz, K | 1 |
| Strauss, WS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| 5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas[NCT05850377] | 90 participants (Anticipated) | Observational | 2023-06-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for aminolevulinic acid and Arachnoidal Cerebellar Sarcoma, Circumscribed
| Article | Year |
|---|---|
5-ALA fluorescence-assisted surgery in pediatric brain tumors: report of three cases and review of the literature.
Topics: Adolescent; Aminolevulinic Acid; Brain Neoplasms; Child; Female; Fluorescence; Glioblastoma; Humans; | 2014 |
8 other studies available for aminolevulinic acid and Arachnoidal Cerebellar Sarcoma, Circumscribed
| Article | Year |
|---|---|
The Use of 5-Aminolevulinic Acid to Assist Gross Total Resection of Paediatric Posterior Fossa Tumours.
Topics: Administration, Oral; Aminolevulinic Acid; Child; Child, Preschool; Ependymoma; Female; Humans; Infr | 2020 |
Accumulation of protoporphyrin IX in medulloblastoma cell lines and sensitivity to subsequent photodynamic treatment.
Topics: Aminolevulinic Acid; ATP Binding Cassette Transporter, Subfamily G, Member 2; Cell Line, Tumor; Ferr | 2018 |
Intra-operative 5-aminolevulinic acid (ALA)-induced fluorescence of medulloblastoma: phenotypic variability and CD133(+) expression according to different fluorescence patterns.
Topics: AC133 Antigen; Aminolevulinic Acid; Antigens, CD; Cerebellar Neoplasms; Fluorescent Dyes; Glycoprote | 2014 |
Fluorescence-guided surgery with 5-aminolevulinic acid for resection of brain tumors in children--a technical report.
Topics: Adolescent; Aminolevulinic Acid; Astrocytoma; Brain Neoplasms; Child; Child, Preschool; Feasibility | 2014 |
Kinetics of porphyrin fluorescence accumulation in pediatric brain tumor cells incubated in 5-aminolevulinic acid.
Topics: Aminolevulinic Acid; Brain Neoplasms; Cell Line, Tumor; Child; Ependymoma; Fluorescence; Humans; Med | 2014 |
The use of 5-ALA to assist complete removal of residual non-enhancing part of childhood medulloblastoma: a case report.
Topics: Aminolevulinic Acid; Cerebellar Neoplasms; Child; Combined Modality Therapy; Follow-Up Studies; Huma | 2015 |
ALA-induced porphyrin accumulation in medulloblastoma and its use for fluorescence-guided surgery.
Topics: Adolescent; Aminolevulinic Acid; Anti-Inflammatory Agents; Brain Neoplasms; Dexamethasone; Evoked Po | 2011 |
In vitro comparison of hypericin and 5-aminolevulinic acid-derived protoporphyrin IX for photodynamic inactivation of medulloblastoma cells.
Topics: Aminolevulinic Acid; Anthracenes; Cell Line, Tumor; Cerebellar Neoplasms; Humans; Medulloblastoma; M | 2012 |