aminolevulinic acid has been researched along with Alopecia Circumscripta in 8 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Photodynamic therapy (PDT) with aminolevulinic acid or methyl 5-aminolevulinic acid (MAL) has been tried for the treatment of alopecia areata (AA)." | 3.76 | Photodynamic therapy with methyl 5-aminolevulinate acid might be ineffective in recalcitrant alopecia totalis regardless of using a microneedle roller to increase skin penetration. ( Kim, BJ; Kim, MN; Lee, JW; Li, K; Yoo, KH, 2010) |
| " The main adverse effects in ALA-PDT treatment were mild edema and tolerable pain, and no adverse effect was observed in red-light treatment." | 3.01 | Treatment of androgenetic alopecia with 5-aminolevulinic acid photodynamic therapy: A randomized, placebo-controlled, split-scalp study of efficacy and safety. ( Cao, Z; Hu, W; Liu, X; Wang, P; Wang, X; Zhang, G; Zhang, L; Zhang, Y; Zhou, Z, 2021) |
| " The adverse effects of ALA-PDT were mild, which indicated safety and tolerability of this treatment." | 3.01 | Treatment of androgenetic alopecia with 5-aminolevulinic acid photodynamic therapy: A randomized, placebo-controlled, split-scalp study of efficacy and safety. ( Cao, Z; Hu, W; Liu, X; Wang, P; Wang, X; Zhang, G; Zhang, L; Zhang, Y; Zhou, Z, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 3 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| Linares-González, L | 1 |
| Ródenas-Herranz, T | 1 |
| Sáenz-Guirado, S | 1 |
| Ruiz-Villaverde, R | 1 |
| Cao, Z | 1 |
| Liu, X | 1 |
| Zhang, L | 1 |
| Zhang, Y | 1 |
| Zhou, Z | 1 |
| Zhang, G | 1 |
| Wang, P | 1 |
| Hu, W | 1 |
| Wang, X | 1 |
| Giuffrida, R | 1 |
| Borgia, F | 1 |
| Marafioti, I | 1 |
| Riso, G | 1 |
| Cannavò, SP | 1 |
| Lee, JW | 2 |
| Yoo, KH | 2 |
| Kim, BJ | 2 |
| Kim, MN | 2 |
| Li, K | 1 |
| Fernández-Guarino, M | 1 |
| Harto, A | 1 |
| García-Morales, I | 1 |
| Pérez-García, B | 1 |
| Arrazola, JM | 1 |
| Jaén, P | 1 |
| Bissonnette, R | 1 |
| Shapiro, J | 1 |
| Zeng, H | 1 |
| McLean, DI | 1 |
| Lui, H | 1 |
| Giorgio, CM | 1 |
| Babino, G | 1 |
| Caccavale, S | 1 |
| Russo, T | 1 |
| De Rosa, AB | 1 |
| Alfano, R | 1 |
| Fulgione, E | 1 |
| Argenziano, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of Hair Transplantation Compared With Hypodermic Needle Irritation in Alopecia Areata[NCT01385839] | 4 participants (Actual) | Interventional | 2009-10-31 | Terminated (stopped due to low enrollment) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for aminolevulinic acid and Alopecia Circumscripta
| Article | Year |
|---|---|
Treatment of androgenetic alopecia with 5-aminolevulinic acid photodynamic therapy: A randomized, placebo-controlled, split-scalp study of efficacy and safety.
Topics: Alopecia Areata; Aminolevulinic Acid; Humans; Photochemotherapy; Photosensitizing Agents; Scalp; Tre | 2021 |
Topical photodynamic therapy with 5-aminolaevulinic acid does not induce hair regrowth in patients with extensive alopecia areata.
Topics: Adult; Alopecia Areata; Aminolevulinic Acid; Dose-Response Relationship, Drug; Female; Hair; Humans; | 2000 |
6 other studies available for aminolevulinic acid and Alopecia Circumscripta
| Article | Year |
|---|---|
Successful response to photodynamic therapy with 5-aminolevulinic acid nanoemulsified gel in a patient with universal alopecia areata refractory to conventional treatment.
Topics: Alopecia Areata; Aminolevulinic Acid; Humans; Photochemotherapy | 2020 |
Combination of tacalcitol ointment and photodynamic therapy for the treatment of follicular mucinosis of the scalp.
Topics: Alopecia Areata; Aminolevulinic Acid; Dermatologic Agents; Dihydroxycholecalciferols; Drug Therapy, | 2019 |
Photodynamic therapy with methyl 5-aminolevulinate acid combined with microneedle treatment in patients with extensive alopecia areata.
Topics: Adult; Alopecia Areata; Aminolevulinic Acid; Female; Humans; Injections, Intradermal; Male; Needles; | 2010 |
Photodynamic therapy with methyl 5-aminolevulinate acid might be ineffective in recalcitrant alopecia totalis regardless of using a microneedle roller to increase skin penetration.
Topics: Adult; Alopecia Areata; Aminolevulinic Acid; Biopsy; Drug Delivery Systems; Equipment Design; Female | 2010 |
Failure to treat alopecia areata with photodynamic therapy.
Topics: Adult; Aged; Alopecia Areata; Aminolevulinic Acid; Face; Female; Hair; Humans; Male; Middle Aged; Ph | 2008 |
Combination of photodynamic therapy with 5-aminolaevulinic acid and microneedling in the treatment of alopecia areata resistant to conventional therapies: our experience with 41 patients.
Topics: Adult; Alopecia Areata; Aminolevulinic Acid; Combined Modality Therapy; Dry Needling; Female; Humans | 2020 |