aminolevulinic acid has been researched along with Adenoma in 13 studies
Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.
Adenoma: A benign epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Incomplete resection of pituitary adenomas may result in recurrence." | 5.43 | Efficacy of 5-aminolevulinic acid based photodynamic therapy in pituitary adenomas-experimental study on rat and human cell cultures. ( Beseoglu, K; Cornelius, JF; Hänggi, D; Kamp, MA; Neumann, LM; Senger, B; Slotty, PJ; Steiger, HJ, 2016) |
| "In Group II human pituitary adenoma cell cultures were obtained from surgically resected adenoma tissue (n=15)." | 5.43 | Efficacy of 5-aminolevulinic acid based photodynamic therapy in pituitary adenomas-experimental study on rat and human cell cultures. ( Beseoglu, K; Cornelius, JF; Hänggi, D; Kamp, MA; Neumann, LM; Senger, B; Slotty, PJ; Steiger, HJ, 2016) |
| "Human pituitary adenoma cells could also be killed by 5-ALA PDT, however this required higher 5-ALA concentrations." | 5.43 | Efficacy of 5-aminolevulinic acid based photodynamic therapy in pituitary adenomas-experimental study on rat and human cell cultures. ( Beseoglu, K; Cornelius, JF; Hänggi, D; Kamp, MA; Neumann, LM; Senger, B; Slotty, PJ; Steiger, HJ, 2016) |
| "From 2004 to 2007, 25 patients suffering from primary and secondary hyperparathyroidism underwent minimally invasive videoscopic-assisted parathyroidectomy after oral photosensitization with aminolevulinic acid (ALA)." | 3.76 | Fluorescence-guided minimally invasive parathyroidectomy: clinical experience with a novel intraoperative detection technique for parathyroid glands. ( Hupp, L; Post, S; Prosst, RL; Weiss, J; Willeke, F, 2010) |
| "A 72-year-old man with primary hyperparathyroidism underwent minimally invasive videoscopically assisted parathyroidectomy after photosensitization with aminolevulinic acid." | 3.73 | Fluorescence-guided minimally invasive parathyroidectomy: a novel detection technique for parathyroid glands. ( Gahlen, J; Post, S; Prosst, RL; Schroeter, L; Willeke, F, 2006) |
| "Four patients with known gastric adenoma (n = 1), macroscopically undetected but histologically proven esophageal squamous cell cancer (n = 1), suspected early cancer of the esophagus (n = 1), and multiple duodenal adenomas (n = 1) were sensitized with 5-aminolevulinic acid administered orally (15 mg/kg body weight)." | 3.70 | Endoscopic photodynamic diagnosis: oral aminolevulinic acid is a marker of GI cancer and dysplastic lesions. ( Hahn, EG; Hochberger, J; Mayinger, B; Reh, H, 1999) |
| "A total of 39 patients with pituitary adenomas were enrolled between June 2015 and January 2018 in 2, sequential, IRB-approved studies." | 1.48 | Intraoperative near-infrared imaging with receptor-specific versus passive delivery of fluorescent agents in pituitary adenomas. ( Buch, L; Cho, SS; Grady, MS; Jeon, J; Lee, JYK; Low, PS; Nag, S; Nasrallah, M; Singhal, S, 2018) |
| "Incomplete resection of pituitary adenomas may result in recurrence." | 1.43 | Efficacy of 5-aminolevulinic acid based photodynamic therapy in pituitary adenomas-experimental study on rat and human cell cultures. ( Beseoglu, K; Cornelius, JF; Hänggi, D; Kamp, MA; Neumann, LM; Senger, B; Slotty, PJ; Steiger, HJ, 2016) |
| "In Group II human pituitary adenoma cell cultures were obtained from surgically resected adenoma tissue (n=15)." | 1.43 | Efficacy of 5-aminolevulinic acid based photodynamic therapy in pituitary adenomas-experimental study on rat and human cell cultures. ( Beseoglu, K; Cornelius, JF; Hänggi, D; Kamp, MA; Neumann, LM; Senger, B; Slotty, PJ; Steiger, HJ, 2016) |
| "Human pituitary adenoma cells could also be killed by 5-ALA PDT, however this required higher 5-ALA concentrations." | 1.43 | Efficacy of 5-aminolevulinic acid based photodynamic therapy in pituitary adenomas-experimental study on rat and human cell cultures. ( Beseoglu, K; Cornelius, JF; Hänggi, D; Kamp, MA; Neumann, LM; Senger, B; Slotty, PJ; Steiger, HJ, 2016) |
| "But, the role of PDT for unresectable pituitary adenomas deserves further investigations." | 1.43 | 5-ALA Fluorescence in Native Pituitary Adenoma Cell Lines: Resection Control and Basis for Photodynamic Therapy (PDT)? ( Ewelt, C; Fortmann, T; Greve, B; Nemes, A; Poeschke, S; Prevedello, D; Santacroce, A; Senner, V; Stummer, W, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, X | 1 |
| Zheng, M | 1 |
| Zou, Y | 1 |
| Wang, J | 1 |
| Zhang, L | 1 |
| Yin, R | 1 |
| Chang, SW | 1 |
| Donoho, DA | 1 |
| Zada, G | 1 |
| Cho, SS | 1 |
| Jeon, J | 1 |
| Buch, L | 1 |
| Nag, S | 1 |
| Nasrallah, M | 1 |
| Low, PS | 1 |
| Grady, MS | 1 |
| Singhal, S | 1 |
| Lee, JYK | 1 |
| Neumann, LM | 1 |
| Beseoglu, K | 1 |
| Slotty, PJ | 1 |
| Senger, B | 1 |
| Kamp, MA | 1 |
| Hänggi, D | 1 |
| Steiger, HJ | 1 |
| Cornelius, JF | 1 |
| Nemes, A | 1 |
| Fortmann, T | 1 |
| Poeschke, S | 1 |
| Greve, B | 1 |
| Prevedello, D | 1 |
| Santacroce, A | 1 |
| Stummer, W | 1 |
| Senner, V | 1 |
| Ewelt, C | 1 |
| Eljamel, MS | 1 |
| Leese, G | 1 |
| Moseley, H | 1 |
| Prosst, RL | 2 |
| Weiss, J | 1 |
| Hupp, L | 1 |
| Willeke, F | 2 |
| Post, S | 2 |
| Endlicher, E | 2 |
| Gelbmann, CM | 1 |
| Knüchel, R | 2 |
| Fürst, A | 1 |
| Szeimies, RM | 2 |
| Gölder, SK | 1 |
| Schölmerich, J | 2 |
| Lottner, C | 1 |
| Messmann, H | 2 |
| Schroeter, L | 1 |
| Gahlen, J | 1 |
| Campbell, DL | 1 |
| Gudgin-Dickson, EF | 1 |
| Forkert, PG | 1 |
| Pottier, RH | 1 |
| Kennedy, JC | 1 |
| Hauser, T | 1 |
| Kullmann, F | 1 |
| Bäumler, W | 1 |
| Eker, C | 1 |
| Montán, S | 1 |
| Jaramillo, E | 1 |
| Koizumi, K | 1 |
| Rubio, C | 1 |
| Andersson-Engels, S | 1 |
| Svanberg, K | 1 |
| Svanberg, S | 1 |
| Slezak, P | 1 |
| Mayinger, B | 1 |
| Reh, H | 1 |
| Hochberger, J | 1 |
| Hahn, EG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Correlation of Surgical Colorectal Cancer Specimen Pathology With the Fluorescence of Photodynamic Diagnostics (PDD): a Clinical Pilot Study[NCT03272659] | Phase 2 | 0 participants (Actual) | Interventional | 2018-04-01 | Withdrawn (stopped due to Long process and due to strict deadline, project was stopped.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for aminolevulinic acid and Adenoma
| Article | Year |
|---|---|
Use of optical fluorescence agents during surgery for pituitary adenomas: current state of the field.
Topics: Adenoma; Aminolevulinic Acid; Fluorescent Dyes; Humans; Optical Imaging; Pituitary Neoplasms; Surger | 2019 |
1 trial available for aminolevulinic acid and Adenoma
| Article | Year |
|---|---|
Intraoperative optical identification of pituitary adenomas.
Topics: Adenoma; Aminolevulinic Acid; Diagnostic Imaging; False Negative Reactions; False Positive Reactions | 2009 |
11 other studies available for aminolevulinic acid and Adenoma
| Article | Year |
|---|---|
5-Aminolevulinic acid induced photodynamic therapy (ALA-PDT) for erosive adenomatosis of the nipple: A case report.
Topics: Adenoma; Adult; Aminolevulinic Acid; Breast Neoplasms; Female; Humans; Nipples; Papilloma; Photochem | 2021 |
Intraoperative near-infrared imaging with receptor-specific versus passive delivery of fluorescent agents in pituitary adenomas.
Topics: Adenoma; Adult; Aged; Aminolevulinic Acid; Drug Delivery Systems; Female; Fluorescent Dyes; Folate R | 2018 |
Efficacy of 5-aminolevulinic acid based photodynamic therapy in pituitary adenomas-experimental study on rat and human cell cultures.
Topics: Adenoma; Aminolevulinic Acid; Animals; Biological Assay; Cell Line, Tumor; Cell Survival; Colorimetr | 2016 |
5-ALA Fluorescence in Native Pituitary Adenoma Cell Lines: Resection Control and Basis for Photodynamic Therapy (PDT)?
Topics: Adenoma; Aminolevulinic Acid; Cell Line, Tumor; Flow Cytometry; Fluorescence; Humans; Photochemother | 2016 |
Fluorescence-guided minimally invasive parathyroidectomy: clinical experience with a novel intraoperative detection technique for parathyroid glands.
Topics: Adenoma; Adult; Aged; Aminolevulinic Acid; Feasibility Studies; Female; Humans; Hyperparathyroidism; | 2010 |
Hexaminolevulinate-induced fluorescence endoscopy in patients with rectal adenoma and cancer: a pilot study.
Topics: Adenoma; Aged; Aged, 80 and over; Aminolevulinic Acid; Biopsy; Carcinoma in Situ; Cell Transformatio | 2004 |
Fluorescence-guided minimally invasive parathyroidectomy: a novel detection technique for parathyroid glands.
Topics: Adenoma; Aged; Aminolevulinic Acid; Atrophy; Fluorescence; Humans; Hyperparathyroidism; Male; Minima | 2006 |
Detection of early stages of carcinogenesis in adenomas of murine lung by 5-aminolevulinic acid-induced protoporphyrin IX fluorescence.
Topics: Adenoma; Aminolevulinic Acid; Animals; Bronchoscopy; Fluorescence; Fluorometry; Lung; Lung Neoplasms | 1996 |
[Photodynamic diagnosis of gastrointestinal precancerous lesions after sensitization with 5-aminolevulinic acid. A pilot study].
Topics: Adenoma; Adult; Aged; Aminolevulinic Acid; Barrett Esophagus; Colitis, Ulcerative; Colorectal Neopla | 1998 |
Clinical spectral characterisation of colonic mucosal lesions using autofluorescence and delta aminolevulinic acid sensitisation.
Topics: Adenoma; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Colon; Colonic Neoplasms; Colonoscopy; | 1999 |
Endoscopic photodynamic diagnosis: oral aminolevulinic acid is a marker of GI cancer and dysplastic lesions.
Topics: Adenoma; Adult; Aged; Aged, 80 and over; Aminolevulinic Acid; Duodenal Neoplasms; Endoscopy, Digesti | 1999 |