Page last updated: 2024-10-16

aminolevulinic acid and Acute Disease

aminolevulinic acid has been researched along with Acute Disease in 84 studies

Aminolevulinic Acid: A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS.
5-aminolevulinic acid : The simplest delta-amino acid in which the hydrogens at the gamma position are replaced by an oxo group. It is metabolised to protoporphyrin IX, a photoactive compound which accumulates in the skin. Used (in the form of the hydrochloride salt)in combination with blue light illumination for the treatment of minimally to moderately thick actinic keratosis of the face or scalp.

Acute Disease: Disease having a short and relatively severe course.

Research Excerpts

ExcerptRelevanceReference
"A 43-yr-old man with abdominal fullness was treated with oral cimetidine during remission of acute intermittent porphyria."7.67Clinical usefulness of cimetidine for the treatment of acute intermittent porphyria--a preliminary report. ( Hirayama, C; Horie, Y; Udagawa, M, 1987)
"The nonerythropoietic component of early labeled bilirubin in plasma and bile was studied in 7 patients with acute infectious hepatitis during the late convalescent stage, in 13 patients with Laennec-type liver cirrhosis, and in 7 control subjects after intravenous injection of a tracer dose (2."7.65The effects of acute infectious hepatitis and cirrhosis of the liver on the nonerythropoietic component of early bilirubin. ( Endo, O; Fukushima, K; Kamiyo, A; Tarao, K, 1976)
"The effects of dietary manipulations on excretion of the porphyrin precursors, delta-aminolevulinic acid (ALA), and porphobilinogen (PBG) were studied in eight patients with acute intermittent porphyria."7.65Comparative effects of glycerol and dextrose on porphyrin precursor excretion in acute intermittent porphyria. ( Bonkowsky, HL; Collins, AR; Doherty, JM; Hess, RA; Magnussen, CR; Tschudy, DP, 1976)
"Porphyria has been associated with an increase in plasma levels of 5-aminolevulinic acid and porphobilinogen."5.29Altered 5-aminolevulinic acid metabolism leading to pseudoporphyria in hemodialysed patients. ( Del C Batlle, AM; Guolo, M; Melito, V; Parera, V; Stella, AM, 1996)
"In acute infectious hepatitis patients, the mean cumulative radioactivity readings for both plasma and bile in 4 hours were approximately twice that found in control subjects."5.26The effects of acute infectious hepatitis and cirrhosis of the liver on the nonerythropoietic component of early bilirubin. ( Endo, O; Fukushima, K; Kamiyo, A; Tarao, K, 1976)
"Porphyrias are a group of eight rare inherited metabolic disorders of heme biosynthesis pathway."4.86Porphyrias at a glance: diagnosis and treatment. ( Brancaleoni, V; Cappellini, MD; Di Pierro, E; Graziadei, G; Tavazzi, D, 2010)
"We report two cases of acute urinary retention (AUR) occurred after intra-urethral aminolevulinic acid (ALA)-mediated photodynamic therapy (PDT) in elderly females (>66 years old) with urethral condylomas."3.79Acute urinary retention in elderly female patients after photodynamic therapy of urethral condyloma--report of two cases. ( Huang, Z; Song, XD; Wang, HW; Wang, XL; Zhang, LL, 2013)
"Results of NTBC therapy used in three infants with type I tyrosinemia who presented with acute liver failure are reported."3.70[Favorable outcome of treatment with NTBC of acute liver insufficiency disclosing hereditary tyrosinemia type I]. ( Barkaoui, E; Bernard, O; Debray, D; Habès, D; Ogier, H, 1999)
" A provisional diagnosis of acute intermittent porphyria was made and was confirmed by the increased levels of urinary delta-aminolevulinic acid (ALA) and porphobilinogen (PBG)."3.68Acute intermittent porphyria. A perplexing case. ( Arena, A; Russo, P; Scuderi, D, 1992)
"A simple qualitative procedure for demonstrating increased delta-aminolevulinic acid (ALA) in urine is needed to identify individuals with an inherited deficiency of the enzyme ALA dehydratase, a newly described porphyria-like syndrome."3.67Simple screening test for qualitative detection of increased delta-aminolevulinic acid in urine. ( Tishler, PV; Winston, SH, 1984)
"A 43-yr-old man with abdominal fullness was treated with oral cimetidine during remission of acute intermittent porphyria."3.67Clinical usefulness of cimetidine for the treatment of acute intermittent porphyria--a preliminary report. ( Hirayama, C; Horie, Y; Udagawa, M, 1987)
" These findings cast doubt on the possibility that ALA or porphobilinogen is responsible for the production of the neural manifestations of acute porphyria."3.65Prophyrin precursors in blood, urine and cerebrospinal fluid in acute porphyria. ( Percy, VA; Shanley, BC, 1977)
"The nonerythropoietic component of early labeled bilirubin in plasma and bile was studied in 7 patients with acute infectious hepatitis during the late convalescent stage, in 13 patients with Laennec-type liver cirrhosis, and in 7 control subjects after intravenous injection of a tracer dose (2."3.65The effects of acute infectious hepatitis and cirrhosis of the liver on the nonerythropoietic component of early bilirubin. ( Endo, O; Fukushima, K; Kamiyo, A; Tarao, K, 1976)
"The effects of dietary manipulations on excretion of the porphyrin precursors, delta-aminolevulinic acid (ALA), and porphobilinogen (PBG) were studied in eight patients with acute intermittent porphyria."3.65Comparative effects of glycerol and dextrose on porphyrin precursor excretion in acute intermittent porphyria. ( Bonkowsky, HL; Collins, AR; Doherty, JM; Hess, RA; Magnussen, CR; Tschudy, DP, 1976)
"Porphyrias are a group of eight rare inherited metabolic disorders of heme biosynthesis pathway."2.46Porphyrias at a glance: diagnosis and treatment. ( Brancaleoni, V; Cappellini, MD; Di Pierro, E; Graziadei, G; Tavazzi, D, 2010)
"Acute porphyrias are inherited disorders caused by partial deficiency of specific heme biosynthesis enzymes."1.30Motor neuropathy in porphobilinogen deaminase-deficient mice imitates the peripheral neuropathy of human acute porphyria. ( Baumgartner, M; Borg, J; Erne, B; Lindberg, RL; Martini, R; Meyer, UA; Ricker, K; Steck, A; Toyka, KV; Zielasek, J, 1999)
"Patients with acute hepatic porphyria are denied essential operations because of concern that general anaesthesia and surgery will precipitate a life threatening porphyric crisis."1.29Safety of general anaesthesia and surgery in acute hepatic porphyria. ( Dover, SB; McColl, KE; Moore, MR; Plenderleith, L, 1994)
"Porphyria has been associated with an increase in plasma levels of 5-aminolevulinic acid and porphobilinogen."1.29Altered 5-aminolevulinic acid metabolism leading to pseudoporphyria in hemodialysed patients. ( Del C Batlle, AM; Guolo, M; Melito, V; Parera, V; Stella, AM, 1996)
"In acute infectious hepatitis patients, the mean cumulative radioactivity readings for both plasma and bile in 4 hours were approximately twice that found in control subjects."1.26The effects of acute infectious hepatitis and cirrhosis of the liver on the nonerythropoietic component of early bilirubin. ( Endo, O; Fukushima, K; Kamiyo, A; Tarao, K, 1976)

Research

Studies (84)

TimeframeStudies, this research(%)All Research%
pre-199055 (65.48)18.7374
1990's18 (21.43)18.2507
2000's7 (8.33)29.6817
2010's4 (4.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Storjord, E1
Dahl, JA1
Landsem, A1
Ludviksen, JK1
Karlsen, MB1
Karlsen, BO1
Brekke, OL1
Wang, HW1
Zhang, LL1
Song, XD1
Huang, Z1
Wang, XL1
Patel, D1
Alhawaj, R1
Wolin, MS1
Sardh, E1
Harper, P1
Andersson, DE1
Floderus, Y2
Mikler, J1
Banovcin, P1
Jesenak, M1
Hamzikova, J1
Statelova, D1
Cappellini, MD1
Brancaleoni, V1
Graziadei, G1
Tavazzi, D1
Di Pierro, E1
Fargion, S1
Fracanzani, AL1
Valenti, L1
Sylantiev, C1
Schoenfeld, N2
Mamet, R2
Groozman, GB1
Drory, VE1
Wilson, GN1
Bloomer, JR1
McGuire, BM1
McColl, KE5
Goldberg, A5
Laiwah, AC2
Junor, B1
MacPhee, GJ1
Thompson, GG1
Arsov, Ts1
Ivanov, E1
Gekova, K1
Knosała, P1
Petelenz, T1
Zuk-Popiołek, I1
Tishler, PV1
Winston, SH1
Bissell, DM2
Bonkowsky, HL2
Schady, W1
Moore, MR7
Graham, DJ2
O'Connor, LJ1
Stewart, PM1
Hensley, WJ1
Romeo, G1
Waldenström, J1
Day, RS1
Eales, L1
Ganda, C1
Joshi, P1
Kramer, S2
Kreimer-Birnbaum, M1
Bannerman, RM1
El-Khatib, M1
Franco-Saenz, R1
Wider de Xifra, EA1
Batlle, AM1
Stella, AM2
Malamud, S1
Doss, M6
von Tiepermann, R1
Schneider, J1
Horie, Y2
Norimoto, M1
Tajima, F1
Sasaki, H1
Nanba, E1
Kawasaki, H1
Dover, SB1
Plenderleith, L1
Gullotti, D1
Schillaci, L1
Amato, S1
Salerno, L1
Guolo, M1
Melito, V1
Parera, V1
Del C Batlle, AM1
Dal Zotto, R1
Discalzi, G1
Scansetti, G1
Messmann, H1
Kullmann, F1
Wild, T1
Knüchel-Clarke, R1
Rüschoff, J1
Gross, V1
Schölmerich, J1
Holstege, A1
Lindberg, RL2
Martini, R1
Baumgartner, M1
Erne, B1
Borg, J1
Zielasek, J1
Ricker, K1
Steck, A1
Toyka, KV1
Meyer, UA2
Barkaoui, E1
Debray, D1
Habès, D1
Ogier, H2
Bernard, O1
Schuurmans, MM1
Hoffmann, F1
Petryka, ZJ1
Lamon, JM1
Frykholm, BC1
Bennett, M1
Tschudy, DP3
Thompson, GT1
Brodie, MJ1
Stutzer, H1
Becker, DM1
Monsalve, V1
Wolff, C1
Gómez, R1
Armas Merino, R1
Canals, C1
Lithner, F1
Wambach, G1
Helber, A1
Caesar, K1
Iffland, R1
Shanley, BC2
Percy, VA2
Neethling, AC1
Beal, MF1
Atuk, NO1
Westfall, TC1
Turner, SM1
Wichmann, T1
Freye, HA1
Peterson, A1
Bossenmaier, I1
Cardinal, R1
Watson, CJ1
Mees, DE1
Frederickson, EL1
Grandchamp, B2
Grelier, M1
Nordmann, Y2
Hofmann, U1
Segewitz, G1
Tarao, K1
Fukushima, K1
Endo, O1
Kamiyo, A1
Mühler, E1
Magnussen, CR2
Collins, AR1
Doherty, JM2
Hess, RA1
Isenschmid, M1
König, C1
Fässli, C1
Haenel, A1
Hänggi, W1
Schneider, H1
Akagi, R1
Prchal, JT1
Eberhart, CE1
Sassa, S1
Thunell, S1
Henrichson, A1
Meissner, P1
Sinclair, J1
Arena, A1
Russo, P1
Scuderi, D1
Bonkovsky, HL1
Healey, JF1
Lourie, AN1
Gerron, GG1
Sieg, I1
Beckh, K1
Kersten, U1
Doss, MO1
Mevasser, R1
Atsmon, A1
Mitchell, G1
Larochelle, J1
Lambert, M1
Michaud, J1
Grenier, A1
Gauthier, M1
Lacroix, J1
Vanasse, M1
Larbrisseau, A1
Beukeveld, GJ1
Wolthers, BG1
Deybach, JC1
Wadman, SK1
Hift, R1
Sohnius, U1
Meissner, PN1
Szabóová, E1
Gajdosík, D1
Yeung Laiwah, AC1
Wehmeier, A1
Fischer, JT1
Goerz, G1
Schneider, W1
Udagawa, M1
Hirayama, C1
Olmos, S1
Abuaud Abo-Mohor, MC1
Liberman, C1
Kaada, B1
Romslo, I1
Sixel-Dietrich, F1
Verspohl, F1
Desaga, U1
Leonhardt, KF1
Frahm, H1
Mustajoki, P1
Tenhunen, R1
Zakhariia, EA1
Temnik, IV1
Romanishin, IaN1
Oey, PL1
Fleury, P1
Hische, EA1
Zuyderhoudt, FM1
Pfändler, U1
Levine, JB1
Cheesman, JO1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Dental Health, Diet, Inflammation and Biomarkers in Patients With Acute Intermittent Porphyria(AIP)[NCT01617642]100 participants (Actual)Observational2012-07-01Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

9 reviews available for aminolevulinic acid and Acute Disease

ArticleYear
Porphyrias at a glance: diagnosis and treatment.
    Internal and emergency medicine, 2010, Volume: 5 Suppl 1

    Topics: Acute Disease; Aminolevulinic Acid; Chronic Disease; Genetic Testing; Heme; Humans; Porphobilinogen;

2010
Treatment choices for people infected with HCV.
    The Journal of antimicrobial chemotherapy, 2004, Volume: 53, Issue:5

    Topics: Acute Disease; Aminolevulinic Acid; Antiviral Agents; Hepacivirus; Hepatitis C; Humans; Liver; Liver

2004
Laboratory evaluation in porphyria.
    Seminars in liver disease, 1982, Volume: 2, Issue:2

    Topics: Acute Disease; Aminolevulinic Acid; Animals; Carrier State; Chemistry, Clinical; Diagnosis, Differen

1982
Neurologic manifestations of acute porphyria.
    Seminars in liver disease, 1982, Volume: 2, Issue:2

    Topics: Acute Disease; Aminolevulinic Acid; Animals; Central Nervous System; Depression; Electrophysiology;

1982
The hepatic porphyrias.
    Progress in medical genetics, 1980, Volume: 4

    Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adolescent; Adult; Aminolevulinic Acid; Chemical Phenom

1980
The porphyrias--a review.
    Haematologia, 1981, Volume: 14, Issue:3

    Topics: Acute Disease; Aged; Alcoholism; Aminolevulinic Acid; Feces; Female; Heme; Humans; Iron; Liver Disea

1981
The neurological manifestations of porphyria: a review.
    Medicine, 1977, Volume: 56, Issue:5

    Topics: Acute Disease; Aminolevulinic Acid; Animals; Heme; Humans; Liver; Liver Diseases; Nervous System; Ne

1977
[Pathobiochemistry of porphyrias].
    Medizinische Klinik, 1977, Sep-23, Volume: 72, Issue:38

    Topics: Acute Disease; Aminolevulinic Acid; Catalase; Chronic Disease; Cytochrome P-450 Enzyme System; Heme;

1977
Pathogenesis of acute porphyria.
    The Quarterly journal of medicine, 1987, Volume: 63, Issue:241

    Topics: Acute Disease; Aminolevulinic Acid; Animals; Heme; Humans; Nervous System; Porphobilinogen; Porphyri

1987

Trials

1 trial available for aminolevulinic acid and Acute Disease

ArticleYear
Plasma porphobilinogen as a sensitive biomarker to monitor the clinical and therapeutic course of acute intermittent porphyria attacks.
    European journal of internal medicine, 2009, Volume: 20, Issue:2

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Arginine; Biomarkers; Chromatography, Ion Exchange; Drug

2009

Other Studies

74 other studies available for aminolevulinic acid and Acute Disease

ArticleYear
Lifestyle factors including diet and biochemical biomarkers in acute intermittent porphyria: Results from a case-control study in northern Norway.
    Molecular genetics and metabolism, 2019, Volume: 128, Issue:3

    Topics: Acute Disease; Adult; Aged; Aminolevulinic Acid; Biomarkers; Case-Control Studies; Cross-Sectional S

2019
Acute urinary retention in elderly female patients after photodynamic therapy of urethral condyloma--report of two cases.
    Photodiagnosis and photodynamic therapy, 2013, Volume: 10, Issue:2

    Topics: Acute Disease; Aged; Aminolevulinic Acid; Buschke-Lowenstein Tumor; Female; Humans; Photochemotherap

2013
Exposure of mice to chronic hypoxia attenuates pulmonary arterial contractile responses to acute hypoxia by increases in extracellular hydrogen peroxide.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2014, Aug-15, Volume: 307, Issue:4

    Topics: Acute Disease; Aminolevulinic Acid; Animals; Antihypertensive Agents; Aorta; Cell Adhesion Molecules

2014
Successful treatment of extreme acute lead intoxication.
    Toxicology and industrial health, 2009, Volume: 25, Issue:2

    Topics: Acute Disease; Adolescent; Aminolevulinic Acid; Antidotes; Charcoal; Chelating Agents; Edetic Acid;

2009
Acute neuropathy mimicking porphyria induced by aminolevulinic acid during photodynamic therapy.
    Muscle & nerve, 2005, Volume: 31, Issue:3

    Topics: Acute Disease; Aged; Aged, 80 and over; Aminolevulinic Acid; Barrett Esophagus; Diagnosis, Different

2005
Tales from the neural genome: the lessons of homozygous porphyria.
    Archives of neurology, 2004, Volume: 61, Issue:11

    Topics: Acute Disease; Aminolevulinic Acid; Humans; Mental Disorders; Porphyrias; Proteomics

2004
Intermittent unexplained abdominal pain: is it porphyria?
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2007, Volume: 5, Issue:11

    Topics: Abdominal Pain; Acute Disease; Adult; Aminolevulinic Acid; Anti-Infective Agents; Cimetidine; Contra

2007
The biochemical basis of the acute porphyrias.
    Biochemical Society transactions, 1983, Volume: 11, Issue:6

    Topics: Acute Disease; Aminolevulinic Acid; Heme; Humans; Nervous System Diseases; Porphyrias; Porphyrins

1983
Charcoal haemoperfusion and haemodialysis in acute intermittent porphyria.
    British medical journal (Clinical research ed.), 1983, Dec-10, Volume: 287, Issue:6407

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Charcoal; Female; Hemoperfusion; Humans; Porphobilinogen;

1983
[Urinary and fecal excretion of porphyrins and their precursors in leukemia patients].
    Vutreshni bolesti, 1983, Volume: 22, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Aminolevulinic Acid; Coproporphyrins; Feces; Female; Humans;

1983
[A case of acute hepatic porphyria].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1983, Nov-15, Volume: 36, Issue:22

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Coproporphyrins; Humans; Liver Diseases; Male; Porphobili

1983
Simple screening test for qualitative detection of increased delta-aminolevulinic acid in urine.
    Clinical chemistry, 1984, Volume: 30, Issue:8

    Topics: Acute Disease; Aminolevulinic Acid; Benzaldehydes; Colorimetry; Humans; Levulinic Acids; Porphobilin

1984
Pathogenesis and treatment of acute intermittent porphyria: discussion paper.
    Journal of the Royal Society of Medicine, 1983, Volume: 76, Issue:5

    Topics: Acute Disease; Aminolevulinic Acid; Blood-Brain Barrier; Heme; Humans; Liver Diseases; Porphobilinog

1983
Monopyrroles in porphyria, psychosis and lead exposure.
    The International journal of biochemistry, 1980, Volume: 12, Issue:5-6

    Topics: 5-Aminolevulinate Synthetase; Acute Disease; Aminolevulinic Acid; Animals; Heme Oxygenase (Decyclizi

1980
Acute intermittent porphyria.
    The American journal of nursing, 1981, Volume: 81, Issue:6

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Female; Humans; Male; Porphobilinogen; Porphyrias; Seizur

1981
An acute attack of variegate porphyria complicated by severe autonomic neuropathy.
    Australian and New Zealand journal of medicine, 1981, Volume: 11, Issue:1

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Autonomic Nervous System Diseases; Female; Humans; Porpho

1981
Acute intermittent porphyria.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1982, Feb-20, Volume: 61, Issue:8

    Topics: Acute Disease; Aminolevulinic Acid; Humans; Levulinic Acids; Liver Diseases; Porphobilinogen; Porphy

1982
Intermittent acute porphyria.
    Archives of internal medicine, 1982, Volume: 142, Issue:8

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Female; Humans; Porphobilinogen; Porphyrias; Porphyrins

1982
Acute intermittent porphyria. A case report.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1981, Nov-14, Volume: 60, Issue:20

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Coproporphyrins; Feces; Female; Humans; Male; Porphobilin

1981
Afro-Americans and acute intermittent porphyria (AIP).
    The International journal of biochemistry, 1980, Volume: 12, Issue:5-6

    Topics: Acute Disease; Adolescent; Adult; Africa; Aminolevulinic Acid; Black People; Child; Child, Preschool

1980
Acute intermittent porphyria--another approach to therapy.
    The International journal of biochemistry, 1980, Volume: 12, Issue:5-6

    Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adult; Aminolevulinic Acid; Ammonia-Lyases; Female; Fol

1980
Acute hepatic porphyria syndrome with porphobilinogen synthase defect.
    The International journal of biochemistry, 1980, Volume: 12, Issue:5-6

    Topics: Acute Disease; Adult; Amino Acids; Aminolevulinic Acid; Erythrocytes; Feces; Female; Humans; Lead; L

1980
Clinical usefulness of cimetidine treatment for acute relapse in intermittent porphyria.
    Clinica chimica acta; international journal of clinical chemistry, 1995, Jan-31, Volume: 234, Issue:1-2

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Blood Glucose; Cimetidine; Coproporphyrins; Feces; Humans

1995
Safety of general anaesthesia and surgery in acute hepatic porphyria.
    Gut, 1994, Volume: 35, Issue:8

    Topics: Acute Disease; Adult; Aged; Aminolevulinic Acid; Anesthesia, General; Child, Preschool; Contraindica

1994
[Clinical and laboratory findings concerning at first dietary and afterwards cimetidine treatment of acute intermittent porphyria].
    La Clinica terapeutica, 1994, Volume: 145, Issue:8

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Cimetidine; Coproporphyrins; Female; Humans; Middle Aged;

1994
Altered 5-aminolevulinic acid metabolism leading to pseudoporphyria in hemodialysed patients.
    The international journal of biochemistry & cell biology, 1996, Volume: 28, Issue:3

    Topics: Acute Disease; Adult; Aged; Aminolevulinic Acid; Case-Control Studies; Female; Hot Temperature; Huma

1996
[The problem of lead exposure in the Piedmont: from the workplace to the general environment].
    Annali dell'Istituto superiore di sanita, 1998, Volume: 34, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Alcohol Drinking; Aminolevulinic Acid; Child; Child, Prescho

1998
Detection of dysplastic lesions by fluorescence in a model of colitis in rats after previous photosensitization with 5-aminolaevulinic acid.
    Endoscopy, 1998, Volume: 30, Issue:4

    Topics: Acute Disease; Aminolevulinic Acid; Animals; Chi-Square Distribution; Chronic Disease; Colitis; Colo

1998
Motor neuropathy in porphobilinogen deaminase-deficient mice imitates the peripheral neuropathy of human acute porphyria.
    The Journal of clinical investigation, 1999, Volume: 103, Issue:8

    Topics: Acute Disease; Aminolevulinic Acid; Animals; Disease Models, Animal; Electrophysiology; Femoral Nerv

1999
[Favorable outcome of treatment with NTBC of acute liver insufficiency disclosing hereditary tyrosinemia type I].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 1999, Volume: 6, Issue:5

    Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Acute Disease; Amino Acid Metabolism, Inborn Errors; Aminolevul

1999
Zinc mesoporphyrin represses induced hepatic 5-aminolevulinic acid synthase and reduces heme oxygenase activity in a mouse model of acute hepatic porphyria.
    Hepatology (Baltimore, Md.), 2001, Volume: 33, Issue:5

    Topics: 5-Aminolevulinate Synthetase; Acute Disease; Aminolevulinic Acid; Animals; Arginine; Cytosol; Drug C

2001
Enzyme abnormalities in the porphyrias.
    Lancet (London, England), 1977, Nov-12, Volume: 2, Issue:8046

    Topics: Acute Disease; Aminolevulinic Acid; Chronic Disease; Humans; Hydroxymethylbilane Synthase; Porphyria

1977
Prevention of acute porphyric attacks by intravenous haematin.
    Lancet (London, England), 1978, Sep-02, Volume: 2, Issue:8088

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Blood Pressure; Circadian Rhythm; Drug Evaluation; Female

1978
Haematin therapy and leucocyte delta-aminolevulinic-acid-synthase activity in prolonged attack of acute porphyria.
    Lancet (London, England), 1979, Jan-20, Volume: 1, Issue:8108

    Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adult; Aminolevulinic Acid; Drug Administration Schedul

1979
Quantitation of 3-ethyl-5-hydroxy-4,5-dimethyl-delta 3-pyrrolin-2-one in the urine of patients with acute intermittent porphyria.
    European journal of clinical investigation, 1979, Volume: 9, Issue:1

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Chromatography, Gas; Female; Heme; Humans; Porphobilinoge

1979
[Letter: Comments and conclusion to H. Stutzer: Typical and atypical roentgen pictures in the acute porphyria. Fortschr. Röntgenstr. 123,6 (1975) 588-590].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1976, Volume: 125, Issue:1

    Topics: Abdomen, Acute; Acute Disease; Aminolevulinic Acid; Diagnosis, Differential; Female; Humans; Middle

1976
[Effect of hematin in acute porphyric relapse].
    Revista medica de Chile, 1979, Volume: 107, Issue:1

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Coproporphyrins; Heme; Hemin; Humans; Male; Porphobilinog

1979
[Acute intermittent porphyria--a clinical review].
    Lakartidningen, 1979, Dec-26, Volume: 76, Issue:52

    Topics: Acute Disease; Aminolevulinic Acid; Diagnosis, Differential; Heme; Humans; Porphobilinogen; Porphyri

1979
Relationships between acute hepatic porphyrias due to genetic variability of primary enzyme defects and limiting function of uroporphyrinogen synthase.
    The International journal of biochemistry, 1978, Volume: 9, Issue:12

    Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adolescent; Adult; Aged; Aminolevulinic Acid; Ammonia-L

1978
[Controlled therapy of lead poisoning].
    Die Medizinische Welt, 1976, Feb-06, Volume: 27, Issue:6

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Edetic Acid; Humans; Lead; Lead Poisoning; Male

1976
Pathogenesis of neural manifestations in acute porphyria.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1977, Apr-02, Volume: 51, Issue:14

    Topics: 5-Aminolevulinate Synthetase; Acute Disease; Aminolevulinic Acid; Animals; Anura; Brain; Heme; Human

1977
Prophyrin precursors in blood, urine and cerebrospinal fluid in acute porphyria.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1977, Jul-30, Volume: 52, Issue:6

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Female; Humans; Middle Aged; Porphobilinogen; Porphyrias;

1977
Catecholamine uptake, accumulation, and release in acute porphyria.
    The Journal of clinical investigation, 1977, Volume: 60, Issue:5

    Topics: Acute Disease; Adolescent; Adult; Aminolevulinic Acid; Animals; Blood Platelets; Catecholamines; Ery

1977
[Pathophysiology and diagnosis of acute intermittent porphyria].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1977, Jun-15, Volume: 32, Issue:12

    Topics: Acute Disease; Aminolevulinic Acid; Erythrocytes; Humans; Hydroxymethylbilane Synthase; Porphobilino

1977
Hematin treatment of acute porphyria. Early remission of an almost fatal relapse.
    JAMA, 1976, Feb-02, Volume: 235, Issue:5

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Female; Follow-Up Studies; Heme; Hemin; Humans; Infusions

1976
Anesthesia and the porphyrias.
    Southern medical journal, 1975, Volume: 68, Issue:1

    Topics: 5-Aminolevulinate Synthetase; Acute Disease; Aminolevulinic Acid; Ammonia-Lyases; Anesthesia; Anesth

1975
[Acute intermittent porphyria. Detection of asymptomatic carriers of the genetic defect].
    La Nouvelle presse medicale, 1975, Jun-14, Volume: 4, Issue:24

    Topics: Acute Disease; Adolescent; Adult; Aged; Aminolevulinic Acid; Ammonia-Lyases; Child; Child, Preschool

1975
Influence of chelation therapy on acute lead intoxication in rats.
    Archives of toxicology, 1975, Nov-20, Volume: 34, Issue:3

    Topics: Acute Disease; Aminolevulinic Acid; Animals; Body Weight; Bone and Bones; Chelating Agents; Dimercap

1975
The effects of acute infectious hepatitis and cirrhosis of the liver on the nonerythropoietic component of early bilirubin.
    The Journal of laboratory and clinical medicine, 1976, Volume: 87, Issue:2

    Topics: Acute Disease; Adult; Aged; Aminolevulinic Acid; Bile; Bilirubin; Erythropoiesis; Female; Hepatitis

1976
[Diagnostic and therapeutic problems in acute intermittent porphyria].
    Der Nervenarzt, 1976, Volume: 47, Issue:2

    Topics: Acute Disease; Adrenal Cortex Hormones; Adult; Aminolevulinic Acid; Analgesics; Colic; Color; Diagno

1976
Comparative effects of glycerol and dextrose on porphyrin precursor excretion in acute intermittent porphyria.
    Metabolism: clinical and experimental, 1976, Volume: 25, Issue:4

    Topics: Acute Disease; Adolescent; Adult; Aged; Aminolevulinic Acid; Dietary Carbohydrates; Dietary Fats; Fe

1976
[Acute intermittent porphyria in pregnancy: glucose or hematin therapy?].
    Schweizerische medizinische Wochenschrift, 1992, Nov-14, Volume: 122, Issue:46

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Drug Therapy, Combination; Female; Glucose Solution, Hype

1992
An acquired acute hepatic porphyria: a novel type of delta-aminolevulinate dehydratase inhibition.
    Clinica chimica acta; international journal of clinical chemistry, 1992, Nov-16, Volume: 212, Issue:1-2

    Topics: Acute Disease; Aminolevulinic Acid; Blotting, Western; Colorimetry; Dithiothreitol; Humans; Male; Mi

1992
Alcoholic beverages in acute porphyria.
    Journal of studies on alcohol, 1992, Volume: 53, Issue:3

    Topics: Acute Disease; Alcoholic Beverages; Aminolevulinic Acid; Dose-Response Relationship, Drug; Genetic C

1992
Acute intermittent porphyria. A perplexing case.
    Italian journal of neurological sciences, 1992, Volume: 13, Issue:4

    Topics: Acute Disease; Aminolevulinic Acid; Female; Humans; Middle Aged; Nervous System Diseases; Pain; Porp

1992
Intravenous heme-albumin in acute intermittent porphyria: evidence for repletion of hepatic hemoproteins and regulatory heme pools.
    The American journal of gastroenterology, 1991, Volume: 86, Issue:8

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Analysis of Variance; Cytochrome P-450 Enzyme System; Fem

1991
Manifestation of acute intermittent porphyria in patients with chronic inflammatory bowel disease.
    Zeitschrift fur Gastroenterologie, 1991, Volume: 29, Issue:11

    Topics: Acute Disease; Adolescent; Adult; Aminolevulinic Acid; Colitis, Ulcerative; Crohn Disease; Humans; P

1991
Experimental latent and acute porphyria in the non-fasted rat; preventive effect of propranolol.
    Scandinavian journal of clinical and laboratory investigation, 1991, Volume: 51, Issue:8

    Topics: Acute Disease; Allylisopropylacetamide; Aminolevulinic Acid; Animals; Coproporphyrins; Dicarbethoxyd

1991
Neurologic crises in hereditary tyrosinemia.
    The New England journal of medicine, 1990, Feb-15, Volume: 322, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Aminolevulinic Acid; Child;

1990
A retrospective study of a patient with homozygous form of acute intermittent porphyria.
    Journal of inherited metabolic disease, 1990, Volume: 13, Issue:5

    Topics: Acute Disease; Aminolevulinic Acid; Child, Preschool; Chromatography, High Pressure Liquid; Erythroc

1990
Safety of vancomycin in acute porphyria.
    British journal of clinical pharmacology, 1990, Volume: 29, Issue:2

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Erythrocytes; Female; Humans; Hydroxymethylbilane Synthas

1990
[Determination of delta aminolevulinic acid in the urine of cows in acute mass lead poisoning].
    Veterinarni medicina, 1987, Volume: 32, Issue:5

    Topics: Acute Disease; Aminolevulinic Acid; Animal Feed; Animals; Cattle; Cattle Diseases; Food Contaminatio

1987
Treatment of acute hepatic porphyria with hematin.
    Journal of hepatology, 1988, Volume: 6, Issue:1

    Topics: Acute Disease; Adult; Aged; Aminolevulinic Acid; Female; Heme; Hemin; Humans; Liver Diseases; Male;

1988
Polychemotherapy of acute myelogenous leukemia in a patient with acute intermittent porphyria.
    Klinische Wochenschrift, 1987, Apr-01, Volume: 65, Issue:7

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Antineoplastic Combined Chemotherapy Protocols; Chemical

1987
Clinical usefulness of cimetidine for the treatment of acute intermittent porphyria--a preliminary report.
    Clinica chimica acta; international journal of clinical chemistry, 1987, Aug-31, Volume: 167, Issue:3

    Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adult; Aminolevulinic Acid; Cimetidine; Humans; Liver D

1987
[Acute porphyria: 2 clinical cases].
    Revista medica de Chile, 1985, Volume: 113, Issue:9

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Female; Humans; Liver; Porphobilinogen; Porphyrias; Porph

1985
Use of transcutaneous nerve stimulation in the attacks of acute intermittent porphyria.
    The International journal of biochemistry, 1985, Volume: 17, Issue:2

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Electric Stimulation Therapy; Female; Humans; Porphobilin

1985
Hyperinsulinemia in acute intermittent porphyria.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1985, Volume: 17, Issue:7

    Topics: Acute Disease; Adolescent; Adult; Aminolevulinic Acid; Female; Glucose Tolerance Test; Humans; Hyper

1985
Clinical and experimental investigations of vasopressin secretion in acute porphyrias.
    Experimental and clinical endocrinology, 1985, Volume: 86, Issue:1

    Topics: Acute Disease; Aminolevulinic Acid; Animals; Arginine Vasopressin; Humans; Hypothalamo-Hypophyseal S

1985
Variant of acute intermittent porphyria with normal erythrocyte uroporphyrinogen-I-synthase activity.
    European journal of clinical investigation, 1985, Volume: 15, Issue:5

    Topics: Acute Disease; Adult; Aminolevulinic Acid; Ammonia-Lyases; Erythrocytes; Humans; Hydroxymethylbilane

1985
[Clinical manifestations of acute intermittent porphyria (review of the literature)].
    Vrachebnoe delo, 1986, Issue:1

    Topics: Acute Disease; Adolescent; Aminolevulinic Acid; Diagnosis, Differential; Diagnostic Errors; Female;

1986
[Acute intermittent porphyria with clinical symptoms of an atypical polyradiculoneuropathy].
    Nederlands tijdschrift voor geneeskunde, 1985, Feb-02, Volume: 129, Issue:5

    Topics: Acute Disease; Adolescent; Aminolevulinic Acid; Diagnosis, Differential; Female; Humans; Menstruatio

1985
[Genetic prognosis of a mother with acute intermittent porphyria (hepatic form)].
    Journal de genetique humaine, 1974, Volume: 22, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aminolevulinic Acid; Female; Genes, Dominant; Genetic Counseling;

1974
A red cell enzyme method for the diagnosis of acute intermittent porphyria.
    Blood, 1974, Volume: 44, Issue:6

    Topics: Acute Disease; Aminolevulinic Acid; Ammonia-Lyases; Erythrocytes; Freezing; Hemolysis; Hot Temperatu

1974