aminoimidazole carboxamide has been researched along with Myocardial Ischemia in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 16 (64.00) | 18.2507 |
| 2000's | 4 (16.00) | 29.6817 |
| 2010's | 5 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liang, GY; Liu, DX; Wang, F; Yu, J; Zhang, DS | 1 |
| Jovanović, A; Jovanović, S; Mohammed Abdul, KS | 1 |
| Hale, SL; Kloner, RA | 1 |
| McGaffin, KR; McTiernan, CF; O'Doherty, RM; O'Donnell, CP; Romano, LC; Witham, WG; Yester, KA | 1 |
| Cao, Y; Gao, E; Lau, WB; Lian, K; Liu, S; Liu, Y; Lu, X; Ma, Y; Pei, H; Qu, Y; Sun, L; Tao, L; Wang, H; Wang, R; Xia, C; Yang, L; Yin, T | 1 |
| Hardie, DG | 1 |
| Baron, SJ; Hurley, RL; Li, J; Miller, EJ; Neumann, D; Russell, RR; Tuerk, R; Wallimann, T; Witters, LA; Young, LH | 1 |
| Li, J; Miller, EJ; Ninomiya-Tsuji, J; Russell, RR; Young, LH | 1 |
| Capano, M; Crompton, M | 1 |
| Bullough, D; Mullane, K | 1 |
| Bullough, D; Galiñanes, M; Hearse, DJ; Mullane, KM; Zhai, X | 1 |
| Burckhartt, B; Cohen, MV; Downey, JM; Mullane, KM; Tsuchida, A; Yang, XM | 2 |
| Alkhulaifi, AM; Pugsley, WB | 1 |
| Barash, P; Curling, P; Hollenberg, M; Leung, JM; Mangano, DT; Mathew, J; Reves, JG; Salmenpera, M; Stanley, T | 1 |
| Fox, KM; Holdright, DR; Sparrow, JL; Steiner, J; Wright, CL | 1 |
| Hori, M; Inoue, M; Kamada, T; Kitakaze, M; Komamura, K; Minamino, T; Morioka, T; Node, K; Sato, H; Takashima, S | 1 |
| Downey, JM; Liu, GS; Mullane, K; Tsuchida, A | 1 |
| Hoshi, K; Ichihara, K; Kano, S; Nakai, T; Satoh, K | 1 |
| Buggé, CJ; Bullough, DA; Kurz, MA; Mullane, KM; Young, MA | 1 |
| de Jong, JW; de Jonge, R; Friedman, J; Macleod, DC; Serruys, PW; Suryapranata, H; van Es, GA | 1 |
| Hill, GE | 1 |
| Bache, RJ; Duncker, DJ; Ishibashi, Y; Klassen, C; Quebbeman, BB | 1 |
| Richardt, G; Schreieck, J | 1 |
| Hori, M; Kitakaze, M; Kuzuya, T; Minamino, T; Mori, H; Node, K; Shinozaki, Y; Takashima, S | 1 |
3 review(s) available for aminoimidazole carboxamide and Myocardial Ischemia
| Article | Year |
|---|---|
AMP-activated protein kinase: the guardian of cardiac energy status.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Apoptosis; Energy Metabolism; Enzyme Activation; Humans; Models, Biological; Multienzyme Complexes; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Necrosis; Protein Serine-Threonine Kinases; Ribonucleosides; Trans-Activators | 2004 |
Harnessing an endogenous cardioprotective mechanism: cellular sources and sites of action of adenosine.
Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Carrier Proteins; Dogs; Endothelium, Vascular; Energy Metabolism; Guinea Pigs; Humans; Myocardial Infarction; Myocardial Ischemia; Myocardium; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rabbits; Rats; Receptors, Purinergic P1; Reperfusion Injury; Ribonucleosides; Signal Transduction | 1995 |
Cardiopulmonary bypass-induced inflammation: is it important?
Topics: Aminoimidazole Carboxamide; Anti-Inflammatory Agents; Cardiopulmonary Bypass; Cell Adhesion; Child; Cytokines; Down-Regulation; Endothelium, Vascular; Endotoxins; Hemofiltration; Humans; Inflammation Mediators; Intercellular Adhesion Molecule-1; Interleukin-1; Interleukin-6; Macrophage-1 Antigen; Myocardial Ischemia; Myocardial Reperfusion Injury; Neutrophils; Nitric Oxide; Nitric Oxide Synthase; Platelet Activation; Ribonucleosides; Serine Proteinase Inhibitors; Systemic Inflammatory Response Syndrome; Tumor Necrosis Factor-alpha; Up-Regulation; Ventricular Dysfunction, Left | 1998 |
3 trial(s) available for aminoimidazole carboxamide and Myocardial Ischemia
| Article | Year |
|---|---|
An initial multicenter, randomized controlled trial on the safety and efficacy of acadesine in patients undergoing coronary artery bypass graft surgery. SPI Research Group.
Topics: Aged; Aminoimidazole Carboxamide; Coronary Artery Bypass; Double-Blind Method; Elective Surgical Procedures; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Ischemia; Ribonucleosides; Safety | 1994 |
Effect of acadesine, a new metabolic agent, on exercise-induced myocardial ischemia in chronic stable angina.
Topics: Aged; Aminoimidazole Carboxamide; Angina Pectoris; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Exercise Test; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Ischemia; Placebos; Ribonucleosides; Time Factors | 1994 |
Effect of acadesine on myocardial ischaemia in patients with coronary artery disease.
Topics: Adult; Aged; Aminoimidazole Carboxamide; Cardiac Catheterization; Coronary Disease; Female; Hemodynamics; Humans; Lactic Acid; Male; Middle Aged; Myocardial Ischemia; Ribonucleosides; Ventricular Function, Left | 1997 |
19 other study(ies) available for aminoimidazole carboxamide and Myocardial Ischemia
| Article | Year |
|---|---|
Role of Phosphorylated AMP-Activated Protein Kinase (AMPK) in Myocardial Insulin Resistance After Myocardial Ischemia-Reperfusion During Cardiopulmonary Bypass Surgery in Dogs.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Cardioplegic Solutions; Cardiopulmonary Bypass; China; Coronary Artery Disease; Dogs; Female; Glucose; Glucose Transporter Type 4; Heart Ventricles; Insulin Resistance; Ischemia; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Phosphorylation; Pyrazoles; Pyrimidines; Ribonucleotides | 2019 |
Exposure to 15% oxygen in vivo up-regulates cardioprotective SUR2A without affecting ERK1/2 and AKT: a crucial role for AMPK.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinase Kinases; Animals; Cardiotonic Agents; Humans; Hypoxia; KATP Channels; MAP Kinase Signaling System; Mice; Myocardial Ischemia; Myocardium; Myocytes, Cardiac; Oxygen; Phosphorylation; Protein Kinases; Proto-Oncogene Proteins c-akt; Ribonucleotides; Signal Transduction; Sulfonylurea Receptors | 2017 |
Cardioprotection with adenosine-regulating agent, GP531: effects on no-reflow, infarct size, and blood flow following ischemia/ reperfusion in the rabbit.
Topics: Adenosine; Aminoimidazole Carboxamide; Analysis of Variance; Animals; Deoxyribonucleosides; Disease Models, Animal; Hemodynamics; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Rabbits; Random Allocation | 2010 |
Cardiac-specific leptin receptor deletion exacerbates ischaemic heart failure in mice.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Enzyme Activation; Glycolysis; Heart Failure; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Cardiovascular; Myocardial Infarction; Myocardial Ischemia; Myocytes, Cardiac; Ribonucleotides; Signal Transduction; STAT3 Transcription Factor; Tamoxifen | 2011 |
Dynamic alteration of adiponectin/adiponectin receptor expression and its impact on myocardial ischemia/reperfusion in type 1 diabetic mice.
Topics: Adenylate Kinase; Adiponectin; Aminoimidazole Carboxamide; Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Mice; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Receptors, Adiponectin; Ribonucleotides | 2011 |
Dual mechanisms regulating AMPK kinase action in the ischemic heart.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Infusions, Intravenous; Male; Multienzyme Complexes; Myocardial Ischemia; Myocardium; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Ribonucleotides | 2005 |
AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Anisomycin; Cell Hypoxia; Enzyme Activation; Glucose; Glucose Transporter Type 4; Intracellular Signaling Peptides and Proteins; Male; MAP Kinase Kinase 3; Mice; Mice, Inbred C57BL; Mice, Transgenic; Multienzyme Complexes; Myocardial Ischemia; p38 Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Protein Transport; Rats; Rats, Sprague-Dawley; Ribonucleotides | 2005 |
Bax translocates to mitochondria of heart cells during simulated ischaemia: involvement of AMP-activated and p38 mitogen-activated protein kinases.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; bcl-2-Associated X Protein; Cells, Cultured; Cytosol; Green Fluorescent Proteins; Metformin; Mitochondria, Heart; Multienzyme Complexes; Myocardial Ischemia; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Protein Transport; Rats; Rats, Sprague-Dawley; Ribonucleotides | 2006 |
Protection against injury during ischemia and reperfusion by acadesine derivatives GP-1-468 and GP-1-668. Studies in the transplanted rat heart.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Aminoimidazole Carboxamide; Animals; Coronary Circulation; Heart Transplantation; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Rats; Rats, Inbred Lew; Ribonucleosides; Ribonucleotides; Ventricular Pressure | 1995 |
Acadesine extends the window of protection afforded by ischaemic preconditioning in conscious rabbits.
Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Disease Models, Animal; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rabbits; Ribonucleosides; Time Factors; Ventricular Fibrillation | 1995 |
Role of acadesine in clinical myocardial protection.
Topics: Aminoimidazole Carboxamide; Clinical Trials as Topic; Humans; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Ribonucleosides | 1995 |
AICA riboside improves myocardial ischemia in coronary microembolization in dogs.
Topics: 5'-Nucleotidase; Adenine Nucleotides; Adenosine; Aminoimidazole Carboxamide; Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Cytosol; Dogs; Energy Metabolism; Myocardial Ischemia; Myocardium; Oxygen Consumption; Ribonucleosides; Thromboembolism | 1994 |
Acadesine extends the window of protection afforded by ischaemic preconditioning.
Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Female; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rabbits; Ribonucleosides; Theophylline; Time Factors | 1994 |
Acadesine lowers temporal threshold for the myocardial infarct size limiting effect of preconditioning.
Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Female; Male; Myocardial Infarction; Myocardial Ischemia; Myocardium; Rabbits; Receptors, Purinergic; Ribonucleosides; Time Factors | 1993 |
Effects of adenine nucleotide analogues on myocardial dysfunction during reperfusion after ischemia in dogs.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenine Nucleotides; Adenosine Monophosphate; Aminoimidazole Carboxamide; Animals; Carbohydrate Metabolism; Cardiomyopathies; Coronary Circulation; Dogs; Female; Hemodynamics; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Ribonucleotides | 1996 |
Cardioprotection with a novel adenosine regulating agent mediated by intravascular adenosine.
Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Cardiotonic Agents; Deoxyribonucleosides; Female; Hemodynamics; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Swine; Swine, Miniature | 1997 |
Acadesine increases blood flow in the collateralized heart during exercise.
Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Collateral Circulation; Coronary Circulation; Dogs; Female; Heart; Hemodynamics; Infusions, Intravenous; Male; Myocardial Ischemia; Physical Conditioning, Animal; Ribonucleosides | 1998 |
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart.
Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiography; Enzyme Inhibitors; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Myocardium; Perfusion; Rats; Rats, Wistar; Reperfusion Injury; Ribonucleosides; Theophylline; Thioinosine; Thiophenes; Time Factors; Ventricular Fibrillation; Xanthines | 1999 |
Improvement by 5-amino-4-imidazole carboxamide riboside of the contractile dysfunction that follows brief periods of ischemia through increases in ecto-5-nucleotidase activity and adenosine release in canine hearts.
Topics: 5'-Nucleotidase; Adenosine; Aminoimidazole Carboxamide; Animals; Dogs; Hemodynamics; Myocardial Contraction; Myocardial Ischemia; Myocardium; Purinergic P1 Receptor Antagonists; Reperfusion; Ribonucleosides | 1999 |