Page last updated: 2024-08-21

aminoimidazole carboxamide and Inflammation

aminoimidazole carboxamide has been researched along with Inflammation in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (5.41)	18.2507
2000's	5 (13.51)	29.6817
2010's	27 (72.97)	24.3611
2020's	3 (8.11)	2.80

Authors

Authors	Studies
Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J	1
Chen, B; Chen, J; Duan, F; Pan, Z; Wang, X; Wang, Y; Wu, M; Zhang, L; Zhang, Y; Zhu, X	1
Duan, X; Gao, Z; Wu, Y; Xue, F; Yang, N	1
Fu, CN; Gao, WS; Qu, YJ; Song, SS; Wei, H; Yue, SW	1
Cieslik, KA; Entman, ML; Trial, J	1
Hosaka, T; Ishida, H; Kitahara, A; Kondo, T; Morita, N; Murashima, T; Onuma, H; Sumitani, Y; Takahashi, K; Tanaka, T	1
Bedard, N; Di Marco, S; Ford, RJ; Gallouzi, IE; Griss, T; Hall, DT; Jones, RG; Ma, JF; Mubaid, S; Omer, A; Pause, A; Sadek, J; Sanchez, BJ; Steinberg, GR; Tremblay, AMK; Wing, SS	1
Hu, L; Hu, XF; Li, HP; Li, M; Lin, LX; Liu, WT; Pan, HL; Shu, Y; Xiang, HC; Zhang, RY; Zhao, YL; Zhu, H	1
Dai, J; Peng, XW; Zhang, L; Zhou, HH	1
Geisslinger, G; Martin, LM; Möller, M; Niederberger, E; Pierre, S; Russe, OQ; Scholich, K; Weiss, U	1
Barroso, E; Coll, T; Gómez-Foix, AM; Palomer, X; Salmerón, E; Salvadó, L; Vázquez-Carrera, M	1
Brüne, B; Kemmerer, M; Namgaladze, D; von Knethen, A	1
Geisslinger, G; King, TS; Kynast, KL; Möser, CV; Niederberger, E; Russe, OQ; Stephan, H	1
Beauloye, C; Bertrand, L; Bouleti, C; Castanares-Zapatero, D; Communi, D; Foretz, M; Gerber, B; Germain, S; Horckmans, M; Horman, S; Laterre, PF; Lecut, C; Mathivet, T; Oury, C; Sommereyns, C; Vanoverschelde, JL; Viollet, B	1
Amrutkar, M; Cansby, E; Durán, EN; Mahlapuu, M; Nerstedt, A; Smith, U	1
Kamoshita, M; Kubota, S; Miyake, S; Nagai, N; Ozawa, Y; Shimmura, S; Tsubota, K; Tsuda, C; Umezawa, K; Yuki, K	1
Botero-Quintero, AM; Darwiche, S; Escobar, DA; Gomez, H; Kautza, BC; Loughran, P; Luciano, J; Rosengart, MR; Zuckerbraun, BS	1
Chen, W; Huang, F; Kou, J; Li, J; Liu, B; Liu, K; Ma, XN; Qi, LW; Wang, Y; Wen, X	1
Coppa, GF; Khan, MM; Marambaud, P; Mulchandani, N; Nicastro, J; Wang, P; Yang, WL; Zhang, F	1
Chen, CC; Chen, HM; Chen, PK; Cheng, YF; Jang, HH; Kao, SH; Kuo, CY; Liang, YJ; Lin, JT; Nong, JY; Young, GH	1
Ai, Q; Dai, J; Ge, P; Lin, L; Zhang, L; Zhou, D	1
Chen, J; Li, XG; Wang, W; Xu, J	1
Cheng, XY; Huang, C; Li, J; Li, YY; Yao, HW	1
Abraham, E; Liu, G; Lorne, E; Park, YJ; Tsuruta, Y; Zhao, X; Zmijewski, JW	1
Andris, F; Baus, E; Denanglaire, S; Flavell, RA; Leo, O; Rongvaux, A; Steuve, J	1
Qiu, J; Wang, X; Xia, M; Zhang, Y	1
Ishida, S; Kubota, S; Kurihara, T; Miyake, S; Noda, K; Ozawa, Y; Sasaki, M; Tsubota, K; Yuki, K	1
Atkins, AR; Coulter, S; Downes, M; Evans, RM; Liddle, C; Rao, R; Sherman, MH; Subramaniam, N; Wilson, C	1
He, Y; Qi, L; Shi, H; Wang, X; Xue, B; Yang, Z; Yu, L	1
Cheng, S; Hao, J; Ji, G; Jiang, Z; Yang, Q; Zhang, Y; Zhao, X	1
Coughlan, K; Moriasi, C; Viollet, B; Wang, Q; Xing, J; Zou, MH	1
Giri, S; Nath, N; Singh, AK; Singh, I; Smith, B; Viollet, B	1
Chang, MY; Ho, FM; Kuo, CL; Lin, WW; Prakash, E	1
Cronstein, BN; Naime, D; Ostad, E	2
Davis, KA; Fabian, TC; Proctor, KG; Ragsdale, DN; Trenthem, LL	1
Croce, MA; Davis, KA; Fabian, TC; Proctor, KG; Ragsdale, DN; Trenthem, LL	1

Reviews

1 review(s) available for aminoimidazole carboxamide and Inflammation

Article	Year
[Advances on the anti-inflammatory and protective effect of AMPK activators]. Sheng li xue bao : [Acta physiologica Sinica], 2019, Apr-25, Volume: 71, Issue:2 Topics: Adiponectin; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Biphenyl Compounds; Enzyme Activation; Inflammation; Metformin; Pyrones; Thiophenes	2019

Other Studies

36 other study(ies) available for aminoimidazole carboxamide and Inflammation

Article	Year
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening. Current protocols in cytometry, 2010, Volume: Chapter 13 Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature	2010
Acadesine alleviates acute pancreatitis-related lung injury by mediating the barrier protective function of pulmonary microvascular endothelial cells. International immunopharmacology, 2022, Volume: 111 Topics: Acute Disease; Acute Lung Injury; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Antioxidants; Endothelial Cells; Humans; Inflammation; Mice; NF-E2-Related Factor 2; Pancreatitis; Ribonucleosides; Signal Transduction	2022
AICAR attenuates postoperative abdominal adhesion formation by inhibiting oxidative stress and promoting mesothelial cell repair. PloS one, 2022, Volume: 17, Issue:9 Topics: Aminoimidazole Carboxamide; Animals; Cadherins; Catalase; Hyaluronic Acid; Inflammation; NF-E2-Related Factor 2; Oxidative Stress; Rats; Reactive Oxygen Species; Ribonucleosides; Ribonucleotides; RNA, Messenger; Superoxide Dismutase; Tissue Adhesions; Transforming Growth Factor beta1; Vimentin	2022
Obesity increases neuropathic pain via the AMPK-ERK-NOX4 pathway in rats. Aging, 2021, 07-29, Volume: 13, Issue:14 Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Apoptosis; Butadienes; Diet, High-Fat; Disease Models, Animal; Enzyme Inhibitors; Ganglia, Spinal; Hypoglycemic Agents; Inflammation; Male; MAP Kinase Signaling System; Metformin; NADPH Oxidase 4; Neuralgia; Nitriles; Obesity; Oxidative Stress; Pain Threshold; Phosphorylation; Rats, Wistar; Ribonucleotides; Spinal Cord	2021
Aicar treatment reduces interstitial fibrosis in aging mice: Suppression of the inflammatory fibroblast. Journal of molecular and cellular cardiology, 2017, Volume: 111 Topics: Aging; Aminoimidazole Carboxamide; Animals; Biomarkers; Cell Count; Fibroblasts; Fibrosis; Inflammation; Male; Mice, Inbred C57BL; Myocardium; Ribonucleotides	2017
Novel Mechanisms Modulating Palmitate-Induced Inflammatory Factors in Hypertrophied 3T3-L1 Adipocytes by AMPK. Journal of diabetes research, 2018, Volume: 2018 Topics: 3T3-L1 Cells; Adenylate Kinase; Adipocytes; Aminoimidazole Carboxamide; Animals; Chemokine CCL2; Inflammation; Metformin; Mice; NF-kappa B; Palmitic Acid; Phosphorylation; Ribonucleotides; Signal Transduction; Triglycerides	2018
The AMPK agonist 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation-associated cachectic muscle wasting. EMBO molecular medicine, 2018, Volume: 10, Issue:7 Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinase Kinases; Animals; Cachexia; Cell Line; Enzyme Activation; Inflammation; Interferon-gamma; Male; Metformin; Mice, Inbred BALB C; Mitochondria; Muscle, Skeletal; Neoplasms, Experimental; Nitric Oxide Synthase Type II; Protein Kinases; Ribonucleotides; Shock, Septic; Tumor Necrosis Factor-alpha	2018
AMPK activation attenuates inflammatory pain through inhibiting NF-κB activation and IL-1β expression. Journal of neuroinflammation, 2019, Feb-12, Volume: 16, Issue:1 Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Antigens, CD; Antigens, Differentiation, Myelomonocytic; CX3C Chemokine Receptor 1; Disease Models, Animal; Enzyme Activation; Freund's Adjuvant; Gene Expression Regulation; Hypoglycemic Agents; Inflammation; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; NF-kappa B; Pain; Pain Threshold; Ribonucleotides; RNA, Small Interfering; Skin	2019
5-Amino-1-β-D-Ribofuranosyl-Imidazole-4-Carboxamide (AICAR) Reduces Peripheral Inflammation by Macrophage Phenotype Shift. International journal of molecular sciences, 2019, Jul-02, Volume: 20, Issue:13 Topics: Aminoimidazole Carboxamide; Animals; Anti-Inflammatory Agents; Cells, Cultured; Edema; Hyperalgesia; Inflammation; Macrophages; Male; Mice, Inbred C57BL; Ribonucleotides	2019
Oleate prevents saturated-fatty-acid-induced ER stress, inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism. Diabetologia, 2013, Volume: 56, Issue:6 Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Biphenyl Compounds; Cell Line; Cell Nucleus; Chromatography, High Pressure Liquid; Endoplasmic Reticulum; Humans; Inflammation; Insulin Resistance; Lipids; Mice; Muscle Cells; Muscle, Skeletal; NF-kappa B; Oleic Acid; Palmitic Acid; Pyrones; Ribonucleotides; Signal Transduction; Thiophenes	2013
AICAR inhibits PPARγ during monocyte differentiation to attenuate inflammatory responses to atherogenic lipids. Cardiovascular research, 2013, Jun-01, Volume: 98, Issue:3 Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Anti-Inflammatory Agents; Atherosclerosis; Cell Differentiation; Cell Line, Tumor; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Enzyme Activation; Enzyme Activators; Gene Expression Regulation; Humans; Inflammation; Interleukin-4; JNK Mitogen-Activated Protein Kinases; Lipoproteins, LDL; Macrophages; Monocytes; Palmitic Acid; Phenotype; PPAR gamma; Ribonucleotides; RNA Interference; RNA, Messenger; Transfection	2013
Activation of the AMP-activated protein kinase reduces inflammatory nociception. The journal of pain, 2013, Volume: 14, Issue:11 Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Behavior, Animal; Enzyme Activation; Hyperalgesia; Inflammation; Male; Metformin; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Skills; Nociception; Pain Measurement; Ribonucleotides; Rotarod Performance Test	2013
Connection between cardiac vascular permeability, myocardial edema, and inflammation during sepsis: role of the α1AMP-activated protein kinase isoform. Critical care medicine, 2013, Volume: 41, Issue:12 Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Capillary Permeability; Cells, Cultured; Coloring Agents; Cytokines; Echocardiography; Edema; Endothelial Cells; Endotoxemia; Evans Blue; Gene Silencing; Heart Diseases; Heart Ventricles; Humans; Inflammation; Lipopolysaccharides; Lung; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peroxidase; Ribonucleosides; Tight Junctions	2013
Partial hepatic resistance to IL-6-induced inflammation develops in type 2 diabetic mice, while the anti-inflammatory effect of AMPK is maintained. Molecular and cellular endocrinology, 2014, Aug-05, Volume: 393, Issue:1-2 Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Blood Glucose; Blotting, Western; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Inflammation; Interleukin-6; Liver; Male; Metformin; Mice; Mice, Inbred C57BL; Real-Time Polymerase Chain Reaction; Ribonucleotides	2014
AMPK-NF-κB axis in the photoreceptor disorder during retinal inflammation. PloS one, 2014, Volume: 9, Issue:7 Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Electroretinography; Inflammation; Male; Mice; NF-kappa B; Photoreceptor Cells; Retinal Diseases; Rhodopsin; Ribonucleotides; Signal Transduction	2014
Adenosine monophosphate-activated protein kinase activation protects against sepsis-induced organ injury and inflammation. The Journal of surgical research, 2015, Volume: 194, Issue:1 Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Autophagy; Cell Adhesion; Cells, Cultured; Cytokines; Endothelial Cells; Inflammation; Leukocytes; Male; Mice; Mice, Inbred C57BL; Multiple Organ Failure; Ribonucleotides; Sepsis	2015
Pharmacological activation of AMPK prevents Drp1-mediated mitochondrial fission and alleviates endoplasmic reticulum stress-associated endothelial dysfunction. Journal of molecular and cellular cardiology, 2015, Volume: 86 Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Carrier Proteins; Caspase 1; Cell Cycle Proteins; Dynamins; Endoplasmic Reticulum Stress; Endothelium, Vascular; Gene Expression Regulation; Humans; Inflammation; Interleukin-1beta; Mitochondrial Dynamics; Rats; Ribonucleotides; Salicylates; Vasodilation	2015
Stimulation of Brain AMP-Activated Protein Kinase Attenuates Inflammation and Acute Lung Injury in Sepsis. Molecular medicine (Cambridge, Mass.), 2015, Jul-30, Volume: 21 Topics: Acute Lung Injury; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Brain; Cell Survival; Energy Metabolism; Gene Expression Regulation; Humans; Inflammation; Male; Mice; Phosphorylation; Ribonucleotides; Sepsis	2015
Activation of AMP-Activated Protein Kinase by Adenine Alleviates TNF-Alpha-Induced Inflammation in Human Umbilical Vein Endothelial Cells. PloS one, 2015, Volume: 10, Issue:11 Topics: Adenine; Adenine Phosphoribosyltransferase; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Cell Adhesion; Cells, Cultured; Enzyme Activation; Gene Expression; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Monocytes; NF-kappa B; Phosphorylation; Protein Transport; Ribonucleotides; RNA, Small Interfering; Tumor Necrosis Factor-alpha	2015
[AMPK activator down-regulates the expression of tissue factor in fulminant hepatitis mice]. Sheng li xue bao : [Acta physiologica Sinica], 2016, Feb-25, Volume: 68, Issue:1 Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Down-Regulation; Erythropoietin; Hepatitis; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Lipopolysaccharides; Male; Mice; NF-kappa B; Thromboplastin; Up-Regulation	2016
Anti-inflammatory activities of fenoterol through β-arrestin-2 and inhibition of AMPK and NF-κB activation in AICAR-induced THP-1 cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 84 Topics: Adrenergic beta-2 Receptor Agonists; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Anti-Inflammatory Agents; beta-Arrestin 2; Cell Line, Tumor; Enzyme Activation; Fenoterol; Humans; Inflammation; Inflammation Mediators; Monocytes; NF-kappa B; Phosphorylation; Protein Kinase Inhibitors; Ribonucleotides; RNA Interference; Signal Transduction; Transfection; Tumor Necrosis Factor-alpha	2016
AMP-activated protein kinase reduces inflammatory responses and cellular senescence in pulmonary emphysema. Oncotarget, 2017, Apr-04, Volume: 8, Issue:14 Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Cell Line; Cellular Senescence; Energy Metabolism; Female; Humans; Inflammation; Lipid Metabolism; Lung; Male; Mice; Mice, Inbred C57BL; Pancreatic Elastase; Pulmonary Disease, Chronic Obstructive; Pulmonary Emphysema; Pyrazoles; Pyrimidines; Respiratory Mucosa; Ribonucleotides; Smoking	2017
Activation of AMPK attenuates neutrophil proinflammatory activity and decreases the severity of acute lung injury. American journal of physiology. Lung cellular and molecular physiology, 2008, Volume: 295, Issue:3 Topics: Acute Disease; Aminoimidazole Carboxamide; Animals; Cyclic AMP-Dependent Protein Kinases; Cytokines; Enzyme Activation; Inflammation; Lipopolysaccharides; Lung; Lung Injury; Male; Mice; Mice, Inbred C57BL; Neutrophils; NF-kappa B; Ribonucleotides; Toll-Like Receptor 4	2008
Metabolic stress boosts humoral responses in vivo independently of inflammasome and inflammatory reaction. Journal of immunology (Baltimore, Md. : 1950), 2011, Feb-15, Volume: 186, Issue:4 Topics: Adenosine Triphosphate; Adjuvants, Immunologic; Aminoimidazole Carboxamide; Animals; Carrier Proteins; Cells, Cultured; Immunoglobulin G; Inflammasomes; Inflammation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; NLR Family, Pyrin Domain-Containing 3 Protein; Oligomycins; Ribonucleotides; Stress, Physiological; Up-Regulation	2011
AMP-activated protein kinase suppresses endothelial cell inflammation through phosphorylation of transcriptional coactivator p300. Arteriosclerosis, thrombosis, and vascular biology, 2011, Volume: 31, Issue:12 Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Aorta; Cell Adhesion; Cells, Cultured; E1A-Associated p300 Protein; Endothelium, Vascular; Gene Expression Regulation; Histone Acetyltransferases; Humans; Inflammation; Monocytes; NF-kappa B; Phosphorylation; Protein Kinase C; Ribonucleotides; Vascular Cell Adhesion Molecule-1	2011
Roles of AMP-activated protein kinase in diabetes-induced retinal inflammation. Investigative ophthalmology & visual science, 2011, Nov-25, Volume: 52, Issue:12 Topics: Administration, Oral; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Blotting, Western; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Inflammation; Injections, Intraperitoneal; Intercellular Adhesion Molecule-1; Mice; Mice, Inbred C57BL; Phosphorylation; Resveratrol; Retinitis; Ribonucleotides; Sirtuin 1; Stilbenes; Transcription Factor RelA; Vascular Endothelial Growth Factor A	2011
Metformin-mediated Bambi expression in hepatic stellate cells induces prosurvival Wnt/β-catenin signaling. Cancer prevention research (Philadelphia, Pa.), 2012, Volume: 5, Issue:4 Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Apoptosis; beta Catenin; Hepatic Stellate Cells; Humans; Hypoglycemic Agents; Inflammation; Lipopolysaccharides; Male; Membrane Proteins; Metformin; Rats; Rats, Sprague-Dawley; Ribonucleotides; Signal Transduction; Wnt Proteins	2012
The full capacity of AICAR to reduce obesity-induced inflammation and insulin resistance requires myeloid SIRT1. PloS one, 2012, Volume: 7, Issue:11 Topics: Aminoimidazole Carboxamide; Animals; Diet, High-Fat; Glucose; Humans; Inflammation; Insulin; Insulin Resistance; Macrophage-1 Antigen; Mice; Mice, Knockout; Muscle, Skeletal; Myeloid Cells; Obesity; Ribonucleotides; Signal Transduction; Sirtuin 1	2012
Genistein suppresses LPS-induced inflammatory response through inhibiting NF-κB following AMP kinase activation in RAW 264.7 macrophages. PloS one, 2012, Volume: 7, Issue:12 Topics: Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Cell Line; Dose-Response Relationship, Drug; Genistein; Inflammation; Interleukin-6; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Phosphorylation; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Ribonucleotides; Signal Transduction; Tumor Necrosis Factor-alpha	2012
Inhibition of AMP-activated protein kinase accentuates lipopolysaccharide-induced lung endothelial barrier dysfunction and lung injury in vivo. The American journal of pathology, 2013, Volume: 182, Issue:3 Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Antigens, CD; Blood Vessels; Cadherins; Cattle; cdc42 GTP-Binding Protein; Cell Membrane Permeability; Cells, Cultured; Endothelial Cells; Enzyme Activation; Humans; Inflammation; Lipopolysaccharides; Lung; Lung Injury; Mice; Mice, Inbred C57BL; Myosin Light Chains; p21-Activated Kinases; Phosphoprotein Phosphatases; Phosphorylation; Phosphothreonine; Protein Phosphatase 2C; Protein Serine-Threonine Kinases; rac1 GTP-Binding Protein; Ribonucleotides; Signal Transduction	2013
5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside inhibits proinflammatory response in glial cells: a possible role of AMP-activated protein kinase. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Jan-14, Volume: 24, Issue:2 Topics: Active Transport, Cell Nucleus; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Brain; Cell Nucleus; Cells, Cultured; Cytokines; Inflammation; Lipopolysaccharides; Macrophages, Peritoneal; Multienzyme Complexes; Neuroglia; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Ribonucleotides; Transcription Factors	2004
Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 gene expression by 5-aminoimidazole-4-carboxamide riboside is independent of AMP-activated protein kinase. Journal of cellular biochemistry, 2008, Feb-15, Volume: 103, Issue:3 Topics: Adenosine Kinase; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Anti-Inflammatory Agents; Cyclooxygenase 2; Electrophoretic Mobility Shift Assay; Enzyme Activation; Gene Expression; Genes, Reporter; Inflammation; Lipopolysaccharides; Macrophages; Mice; Microglia; Multienzyme Complexes; Nitric Oxide Synthase Type II; Protein Binding; Protein Serine-Threonine Kinases; Ribonucleosides; RNA, Messenger; Signal Transduction; Transcription Factors; Transcription, Genetic	2008
The antiinflammatory effects of methotrexate are mediated by adenosine. Advances in experimental medicine and biology, 1994, Volume: 370 Topics: Acyltransferases; Adenosine; Adenosine Deaminase; Aminoimidazole Carboxamide; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Hydroxymethyl and Formyl Transferases; Inflammation; Kinetics; Leukocytes; Methotrexate; Mice; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Purinergic P1 Receptor Antagonists; Ribonucleotides; Theobromine; Xanthines	1994
The antiinflammatory mechanism of methotrexate. Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation. The Journal of clinical investigation, 1993, Volume: 92, Issue:6 Topics: Adenosine; Adenosine Deaminase; Aminoimidazole Carboxamide; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Disease Models, Animal; Female; Inflammation; Kinetics; Leukocytes; Methotrexate; Mice; Mice, Inbred BALB C; Purinergic P1 Receptor Antagonists; Ribonucleotides; Spleen; Theobromine; Time Factors	1993
Endogenous adenosine and secondary injury after chest trauma. The Journal of trauma, 2000, Volume: 49, Issue:5 Topics: Acidosis; Adenosine; Aminoimidazole Carboxamide; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Drug Evaluation, Preclinical; Hemodynamics; Hypercapnia; Inflammation; Leukocyte Count; Peroxidase; Ribonucleosides; Survival Analysis; Swine; Thoracic Injuries; Wounds, Nonpenetrating	2000
Combination therapy that targets secondary pulmonary changes after abdominal trauma. Shock (Augusta, Ga.), 2001, Volume: 15, Issue:6 Topics: Abdominal Abscess; Abdominal Injuries; Aminoimidazole Carboxamide; Animals; Anti-Inflammatory Agents; Blood Pressure; Capillaries; Disease Models, Animal; Hemodynamics; Inflammation; Lactates; Lung; Lung Injury; Neutrophils; Pulmonary Alveoli; Pulmonary Artery; Resuscitation; Ribonucleotides; Shock, Hemorrhagic; Steroids; Swine	2001