Compounds > aminoimidazole carboxamide
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aminoimidazole carboxamide and Cardiovascular Stroke

aminoimidazole carboxamide has been researched along with Cardiovascular Stroke in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (52.38)18.2507
2000's3 (14.29)29.6817
2010's6 (28.57)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Iso, T; Kawakami, R; Koitabashi, N; Kurabayashi, M; Matsui, H; Murakami, M; Obokata, M; Sunaga, H; Yokoyama, T1
Fukushima, A; Furihata, T; Handa, H; Kakutani, N; Kinugawa, S; Maekawa, S; Matsumoto, J; Mizushima, W; Nakano, I; Nambu, H; Sabe, H; Takada, S; Tanaka, S; Yokota, T1
Cieslik, KA; Crawford, JR; Entman, ML; Mejia Osuna, P; Taffet, GE; Trial, J1
Beauloye, C; Bertrand, L; Daskalopoulos, EP; Dufeys, C; Horman, S1
Bøtker, HE; Jessen, N; Kristiansen, SB; Lund, S; Løfgren, B; Nielsen, TT; Nielsen-Kudsk, JE; Schmitz, O; Solskov, L1
Hale, SL; Kloner, RA1
Fisslthaler, B; Fleming, I; Kehl, F; Lange, M; Lotz, C; Pociej, J; Redel, A; Roewer, N; Smul, TM; Stumpner, J1
McGaffin, KR; McTiernan, CF; O'Doherty, RM; O'Donnell, CP; Romano, LC; Witham, WG; Yester, KA1
Dietzel, C; Mangano, DT; Miao, Y; Tudor, IC1
Kloner, RA1
Davies, MK; Flameng, W; Jamieson, WR; Menasché, P1
Bullough, D; Mullane, K1
Burckhartt, B; Cohen, MV; Downey, JM; Mullane, KM; Tsuchida, A; Yang, XM2
Alkhulaifi, AM; Pugsley, WB1
Hudspeth, DA; McGee, DS; Sato, H; Van Wylen, DG; Vinten-Johansen, J; Williams, MW; Zhao, ZQ1
Kingma, JG; Rouleau, JR; Simard, D1
Downey, JM; Liu, GS; Mullane, K; Tsuchida, A1
Aggarwal, A; Comunale, ME; Ghoshal, S; Hollenberg, M; Jain, U; Laflamme, CJ; Mangano, DT; Ngo, L; Ramsay, JG; Ziola, K1
Dorion, M; Kingma, JG; Rouleau, J1

Reviews

2 review(s) available for aminoimidazole carboxamide and Cardiovascular Stroke

ArticleYear
AMPK in cardiac fibrosis and repair: Actions beyond metabolic regulation.
    Journal of molecular and cellular cardiology, 2016, Volume: 91

    Topics: Aging; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Berberine; Cardiomegaly; Extracellular Matrix Proteins; Fibrosis; Gene Expression Regulation; Humans; Metformin; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Resveratrol; Ribonucleotides; Signal Transduction; Stilbenes; Thiazolidinediones; Wound Healing

2016
Harnessing an endogenous cardioprotective mechanism: cellular sources and sites of action of adenosine.
    Journal of molecular and cellular cardiology, 1995, Volume: 27, Issue:4

    Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Carrier Proteins; Dogs; Endothelium, Vascular; Energy Metabolism; Guinea Pigs; Humans; Myocardial Infarction; Myocardial Ischemia; Myocardium; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rabbits; Rats; Receptors, Purinergic P1; Reperfusion Injury; Ribonucleosides; Signal Transduction

1995

Trials

4 trial(s) available for aminoimidazole carboxamide and Cardiovascular Stroke

ArticleYear
Post-reperfusion myocardial infarction: long-term survival improvement using adenosine regulation with acadesine.
    Journal of the American College of Cardiology, 2006, Jul-04, Volume: 48, Issue:1

    Topics: Adenosine; Aged; Aminoimidazole Carboxamide; Coronary Artery Bypass; Double-Blind Method; Female; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion Injury; Preoperative Care; Ribonucleosides; Risk Factors; Survival Rate

2006
Acadesine: a new drug that may improve myocardial protection in coronary artery bypass grafting. Results of the first international multicenter study. Multinational Acadesine Study Group.
    The Journal of thoracic and cardiovascular surgery, 1995, Volume: 110, Issue:4 Pt 1

    Topics: Aminoimidazole Carboxamide; Cause of Death; Coronary Artery Bypass; Coronary Disease; Double-Blind Method; Female; Humans; Male; Middle Aged; Myocardial Infarction; Prospective Studies; Regression Analysis; Ribonucleosides; Risk Factors; Treatment Outcome

1995
Effects of acadesine on the incidence of myocardial infarction and adverse cardiac outcomes after coronary artery bypass graft surgery. Multicenter Study of Perioperative Ischemia (McSPI) Research Group.
    Anesthesiology, 1995, Volume: 83, Issue:4

    Topics: Adenosine; Aged; Aminoimidazole Carboxamide; Coronary Artery Bypass; Double-Blind Method; Female; Hemodynamics; Humans; Incidence; Male; Middle Aged; Myocardial Infarction; Ribonucleosides; Ventricular Function, Left

1995
Electrocardiographic and hemodynamic changes and their association with myocardial infarction during coronary artery bypass surgery. A multicenter study. Multicenter Study of Perioperative Ischemia (McSPI) Research Group.
    Anesthesiology, 1997, Volume: 86, Issue:3

    Topics: Aged; Aminoimidazole Carboxamide; Coronary Artery Bypass; Creatine Kinase; Electrocardiography; Female; Hemodynamics; Humans; Male; Middle Aged; Myocardial Infarction; Myocardium; Predictive Value of Tests; Ribonucleosides; Stroke Volume; Ventricular Function, Left

1997

Other Studies

15 other study(ies) available for aminoimidazole carboxamide and Cardiovascular Stroke

ArticleYear
Activation of cardiac AMPK-FGF21 feed-forward loop in acute myocardial infarction: Role of adrenergic overdrive and lipolysis byproducts.
    Scientific reports, 2019, 08-14, Volume: 9, Issue:1

    Topics: Adrenergic Agents; Aged; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Angina Pectoris; Animals; Catecholamines; Disease Models, Animal; Fatty Acid-Binding Proteins; Fatty Acids; Female; Fibroblast Growth Factors; Humans; Lipolysis; Male; Multivariate Analysis; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Recombinant Proteins; Ribonucleotides; Time Factors; Troponin T

2019
Brain-Derived Neurotrophic Factor Improves Impaired Fatty Acid Oxidation Via the Activation of Adenosine Monophosphate-Activated Protein Kinase-ɑ - Proliferator-Activated Receptor-r Coactivator-1ɑ Signaling in Skeletal Muscle of Mice With Heart Failure.
    Circulation. Heart failure, 2021, Volume: 14, Issue:1

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Brain-Derived Neurotrophic Factor; Exercise Tolerance; Fatty Acids; Heart Failure; Humans; Male; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Mitochondria; Muscle, Skeletal; Myocardial Infarction; Oxidation-Reduction; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Recombinant Proteins; Ribonucleosides

2021
AICAR-dependent AMPK activation improves scar formation in the aged heart in a murine model of reperfused myocardial infarction.
    Journal of molecular and cellular cardiology, 2013, Volume: 63

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Cicatrix; Disease Models, Animal; Enzyme Activation; Fibroblasts; Male; Mice; Myocardial Infarction; Myocardial Reperfusion Injury; Myofibroblasts; Phosphorylation; Ribonucleotides; Ventricular Remodeling; Wound Healing

2013
5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases myocardial glucose uptake during reperfusion and induces late pre-conditioning: potential role of AMP-activated protein kinase.
    Basic & clinical pharmacology & toxicology, 2009, Volume: 105, Issue:1

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Blood Glucose; Glucose; Glucose Transporter Type 4; Glycogen; Heart; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Physical Exertion; Protective Agents; Random Allocation; Rats; Rats, Wistar; Ribonucleotides; Ventricular Pressure

2009
Cardioprotection with adenosine-regulating agent, GP531: effects on no-reflow, infarct size, and blood flow following ischemia/ reperfusion in the rabbit.
    Journal of cardiovascular pharmacology and therapeutics, 2010, Volume: 15, Issue:1

    Topics: Adenosine; Aminoimidazole Carboxamide; Analysis of Variance; Animals; Deoxyribonucleosides; Disease Models, Animal; Hemodynamics; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Rabbits; Random Allocation

2010
Activation of adenosine-monophosphate-activated protein kinase abolishes desflurane-induced preconditioning against myocardial infarction in vivo.
    Journal of cardiothoracic and vascular anesthesia, 2011, Volume: 25, Issue:1

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Anesthetics, Inhalation; Animals; Body Temperature; Cardiotonic Agents; Desflurane; Electrocardiography; Enzyme Activation; Glycogen; Hemodynamics; Hypoglycemic Agents; Immunoprecipitation; Ischemic Preconditioning, Myocardial; Isoflurane; Male; Myocardial Infarction; Myocardium; Rabbits; Ribonucleotides

2011
Cardiac-specific leptin receptor deletion exacerbates ischaemic heart failure in mice.
    Cardiovascular research, 2011, Jan-01, Volume: 89, Issue:1

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Enzyme Activation; Glycolysis; Heart Failure; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Cardiovascular; Myocardial Infarction; Myocardial Ischemia; Myocytes, Cardiac; Ribonucleotides; Signal Transduction; STAT3 Transcription Factor; Tamoxifen

2011
Moving preconditioning from bench to bedside.
    Journal of the American College of Cardiology, 2006, Jul-04, Volume: 48, Issue:1

    Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Coronary Artery Bypass; Humans; Ischemic Preconditioning, Myocardial; Myocardial Infarction; Myocardial Reperfusion Injury; Ribonucleosides; Survival Rate

2006
Acadesine extends the window of protection afforded by ischaemic preconditioning in conscious rabbits.
    Cardiovascular research, 1995, Volume: 29, Issue:5

    Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Disease Models, Animal; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rabbits; Ribonucleosides; Time Factors; Ventricular Fibrillation

1995
Role of acadesine in clinical myocardial protection.
    British heart journal, 1995, Volume: 73, Issue:4

    Topics: Aminoimidazole Carboxamide; Clinical Trials as Topic; Humans; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Ribonucleosides

1995
Acadesine reduces myocardial infarct size by an adenosine mediated mechanism.
    Cardiovascular research, 1995, Volume: 29, Issue:4

    Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Coronary Circulation; Extracellular Space; In Vitro Techniques; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Rabbits; Receptors, Purinergic P1; Regional Blood Flow; Ribonucleosides; Theophylline

1995
Timely administration of AICA riboside reduces reperfusion injury in rabbits.
    Cardiovascular research, 1994, Volume: 28, Issue:7

    Topics: Aminoimidazole Carboxamide; Animals; Autoradiography; Disease Models, Animal; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Rabbits; Ribonucleosides; Tetrazolium Salts

1994
Acadesine extends the window of protection afforded by ischaemic preconditioning.
    Cardiovascular research, 1994, Volume: 28, Issue:3

    Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Female; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Rabbits; Ribonucleosides; Theophylline; Time Factors

1994
Acadesine lowers temporal threshold for the myocardial infarct size limiting effect of preconditioning.
    Cardiovascular research, 1993, Volume: 27, Issue:1

    Topics: Adenosine; Aminoimidazole Carboxamide; Animals; Female; Male; Myocardial Infarction; Myocardial Ischemia; Myocardium; Rabbits; Receptors, Purinergic; Ribonucleosides; Time Factors

1993
Failure of AICA riboside to limit infarct size during acute myocardial infarction in rabbits.
    Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:1

    Topics: Aminoimidazole Carboxamide; Animals; Arrhythmias, Cardiac; Autoradiography; Blood Pressure; Coronary Circulation; Coronary Disease; Heart Rate; Heart Ventricles; Male; Myocardial Infarction; Myocardial Reperfusion; Necrosis; Rabbits; Ribonucleotides; Staining and Labeling; Ventricular Fibrillation

1992