Compounds > aminoimidazole carboxamide
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aminoimidazole carboxamide and Breast Neoplasms

aminoimidazole carboxamide has been researched along with Breast Neoplasms in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (11.11)18.2507
2000's3 (16.67)29.6817
2010's13 (72.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brown, BL; Dobson, PRM; El-Masry, OS1
Bizjak, M; Dolinar, K; Malavašič, P; Pavlin, M; Pirkmajer, S; Pohar, J1
Jiang, W; Liu, S; Tang, Y; Yan, M1
Cheng, XL; Li, B; Li, L; Li, MY; Li, ZQ; Lu, W; Zhou, TY1
Buac, D; Dou, QP; Kona, FR; Seth, AK1
Chen, H; Santen, RJ; Wang, JP; Yue, W1
Gabrielson, E; Jhaveri, TZ; Park, BH; Shang, X; Woo, J1
Chung, FF; Hii, LW; Ho, GF; Leong, CO; Malik, RA; Ng, CH; See, MH; Soo, JS; Taib, NA; Tan, BS; Tan, SH; Teh, YC; Teo, SH; Yip, CH1
Kim, HI; Kim, HS; Kim, JH; Kim, N; Kim, SJ; Lee, HJ; Lee, JO; Lee, YW; Park, SH1
Abdul-Rahman, O; Bai, P; Dér, Á; Fodor, T; Kiss, B; Nagy, L; Szántó, M1
Xie, CW; Xiong, JP; Yang, SX; Zou, YF1
Deng, SS; Huang, XJ; Li, J; Qian, M; Wu, L; Yang, CH; Zang, Y1
Cha, EY; Chang, ES; Kim, JR; Lee, JS; Lee, MS; Thuong, PT; Youn, SH1
Beckers, A; Brusselmans, K; De Schrijver, E; Deboel, L; Derua, R; Foufelle, F; Noël, A; Organe, S; Segers, J; Swinnen, JV; Timmermans, L; Van de Sande, T; Vanderhoydonc, F; Verhoeven, G; Waelkens, E1
Beckers, A; Brusselmans, K; Deboel, L; Derua, R; Organe, S; Swinnen, JV; Timmermans, L; Vanderhoydonc, F; Verhoeven, G; Waelkens, E1
Bullinger, D; Fehm, T; Gleiter, CH; Kammerer, B; Laufer, S; Neubauer, H1
Herenyiova, M; Weber, G; Yeh, YA1
Cerar, O; Cervek, J; Cufer, T; Kolaric, K1

Other Studies

18 other study(ies) available for aminoimidazole carboxamide and Breast Neoplasms

ArticleYear
AMPK Activation of Apoptotic Markers in Human Breast Cancer Cell Lines with Different p53 Backgrounds: MCF-7, MDA-MB-231 and T47D Cells.
    Asian Pacific journal of cancer prevention : APJCP, 2019, Dec-01, Volume: 20, Issue:12

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Cell Cycle; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoglycemic Agents; Poly (ADP-Ribose) Polymerase-1; Receptors, Estrogen; Ribonucleotides; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2019
Combined treatment with Metformin and 2-deoxy glucose induces detachment of viable MDA-MB-231 breast cancer cells in vitro.
    Scientific reports, 2017, 05-11, Volume: 7, Issue:1

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Biphenyl Compounds; Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxyglucose; Enzyme Activation; Female; Humans; Metformin; Pyrones; Ribonucleotides; Thiophenes

2017
PIK3CA mutation sensitizes breast cancer cells to synergistic therapy of PI3K inhibition and AMPK activation.
    Investigational new drugs, 2018, Volume: 36, Issue:5

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Class I Phosphatidylinositol 3-Kinases; Drug Synergism; Humans; Indazoles; Mice, Inbred BALB C; Mice, Nude; Mutation; Protein Kinase Inhibitors; Ribonucleotides; Sulfonamides

2018
Methotrexate and 5-aminoimidazole-4-carboxamide riboside exert synergistic anticancer action against human breast cancer and hepatocellular carcinoma.
    Acta pharmacologica Sinica, 2013, Volume: 34, Issue:7

    Topics: Aminoimidazole Carboxamide; Animals; Apoptosis; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Proliferation; Drug Synergism; Female; Hep G2 Cells; Humans; Liver Neoplasms, Experimental; MCF-7 Cells; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Xenograft Model Antitumor Assays

2013
Regulation of metformin response by breast cancer associated gene 2.
    Neoplasia (New York, N.Y.), 2013, Volume: 15, Issue:12

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Enzyme Activation; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Metformin; Phosphatidylinositol 3-Kinases; Phosphorylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Ribonucleotides; Ubiquitin-Protein Ligases

2013
Adenosine monophosphate activated protein kinase (AMPK), a mediator of estradiol-induced apoptosis in long-term estrogen deprived breast cancer cells.
    Apoptosis : an international journal on programmed cell death, 2015, Volume: 20, Issue:6

    Topics: Aminoimidazole Carboxamide; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Breast Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Estradiol; Estrogens; Fas Ligand Protein; Female; Forkhead Box Protein O3; Forkhead Transcription Factors; Humans; Hypoglycemic Agents; Membrane Proteins; Nuclear Proteins; Proto-Oncogene Proteins; Ribonucleotides

2015
AMP-activated kinase (AMPK) regulates activity of HER2 and EGFR in breast cancer.
    Oncotarget, 2015, Jun-20, Volume: 6, Issue:17

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Blotting, Western; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Survival; ErbB Receptors; Humans; MCF-7 Cells; Mice, Inbred NOD; Mice, SCID; Receptor, ErbB-2; Ribonucleotides; RNA Interference; Xenograft Model Antitumor Assays

2015
Metformin synergizes 5-fluorouracil, epirubicin, and cyclophosphamide (FEC) combination therapy through impairing intracellular ATP production and DNA repair in breast cancer stem cells.
    Apoptosis : an international journal on programmed cell death, 2015, Volume: 20, Issue:10

    Topics: Adenosine Triphosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Antineoplastic Agents; Apoptosis; Biphenyl Compounds; Breast Neoplasms; Cyclophosphamide; DNA Damage; DNA Repair; Drug Combinations; Drug Synergism; Embryonic Stem Cells; Epirubicin; Female; Fibroblasts; Fluorouracil; Glucose; Humans; Hypoglycemic Agents; Lactic Acid; Lung; Metformin; Neoplastic Stem Cells; Pyrones; Ribonucleotides; Thiophenes

2015
Paclitaxel suppresses the viability of breast tumor MCF7 cells through the regulation of EF1α and FOXO3a by AMPK signaling.
    International journal of oncology, 2015, Volume: 47, Issue:5

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Breast Neoplasms; Cell Survival; Female; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Paclitaxel; Peptide Elongation Factor 1; Signal Transduction

2015
Combined Treatment of MCF-7 Cells with AICAR and Methotrexate, Arrests Cell Cycle and Reverses Warburg Metabolism through AMP-Activated Protein Kinase (AMPK) and FOXO1.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Breast Neoplasms; Cell Cycle; Cell Division; Cell Line, Tumor; Cytostatic Agents; Drug Screening Assays, Antitumor; Drug Synergism; Energy Metabolism; Enzyme Induction; Female; Forkhead Box Protein O1; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Glycolysis; Humans; Lactates; MCF-7 Cells; Membrane Potential, Mitochondrial; Methotrexate; Molecular Targeted Therapy; Neoplasm Proteins; Osteosarcoma; Ribonucleotides; RNA Interference; Transcription Factors

2016
AMPK activators suppress breast cancer cell growth by inhibiting DVL3-facilitated Wnt/β-catenin signaling pathway activity.
    Molecular medicine reports, 2017, Volume: 15, Issue:2

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Breast; Breast Neoplasms; Calcimycin; Cell Line, Tumor; Cell Proliferation; Dishevelled Proteins; Enzyme Activation; Female; Humans; Ribonucleotides; Wnt Signaling Pathway

2017
5'-AMP-activated protein kinase (AMPK) regulates progesterone receptor transcriptional activity in breast cancer cells.
    Biochemical and biophysical research communications, 2011, Dec-09, Volume: 416, Issue:1-2

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Breast Neoplasms; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Humans; Metformin; Receptors, Progesterone; Ribonucleotides; RNA, Small Interfering; Transcription, Genetic

2011
Anticancer properties of pomolic acid-induced AMP-activated protein kinase activation in MCF7 human breast cancer cells.
    Biological & pharmaceutical bulletin, 2012, Volume: 35, Issue:1

    Topics: Acetyl-CoA Carboxylase; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Caspase 3; Caspase 9; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Activation; Fatty Acid Synthases; Fatty Acids; Female; G1 Phase; Gene Expression; Genes, p53; Humans; Oleanolic Acid; Phytotherapy; Plant Extracts; Poly(ADP-ribose) Polymerases; Protein Biosynthesis; Ribonucleotides; RNA, Messenger

2012
Mimicry of a cellular low energy status blocks tumor cell anabolism and suppresses the malignant phenotype.
    Cancer research, 2005, Mar-15, Volume: 65, Issue:6

    Topics: Adenosine Monophosphate; Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Biomimetic Materials; Breast Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cell Movement; Cell Survival; Energy Metabolism; Female; Humans; Male; Mice; Mice, Nude; Prostatic Neoplasms; Ribonucleosides; Ribonucleotides; Xenograft Model Antitumor Assays

2005
Methotrexate enhances the antianabolic and antiproliferative effects of 5-aminoimidazole-4-carboxamide riboside.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:9

    Topics: Adenosine Triphosphate; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Line, Tumor; DNA, Neoplasm; Drug Synergism; Enzyme Activation; Humans; Lipids; Methotrexate; Multienzyme Complexes; Nucleotide Deaminases; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Phosphoribosylglycinamide Formyltransferase; Protein Serine-Threonine Kinases; Purines; Ribonucleosides; Ribonucleotides; RNA Interference

2006
Metabolic signature of breast cancer cell line MCF-7: profiling of modified nucleosides via LC-IT MS coupling.
    BMC biochemistry, 2007, Nov-29, Volume: 8

    Topics: Adenosine; Aminoimidazole Carboxamide; Biomarkers, Tumor; Breast Neoplasms; Cell Line; Cell Line, Tumor; Epithelial Cells; Female; Guanosine; Humans; Imidazoles; Ions; Mammary Glands, Human; Metabolic Networks and Pathways; Ribonucleosides; Ribose; S-Adenosylmethionine; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Uridine

2007
Quercetin: synergistic action with carboxyamidotriazole in human breast carcinoma cells.
    Life sciences, 1995, Volume: 57, Issue:13

    Topics: Aminoimidazole Carboxamide; Antineoplastic Agents; Breast Neoplasms; Cell Division; Cell Survival; Drug Synergism; Female; Humans; Quercetin; Signal Transduction; Triazoles; Tumor Cells, Cultured

1995
Combination of 5-fluorouracil, imidazole carboxamide, BCNU and prednisolone (FIB-P) as a salvage chemotherapy in heavily pretreated breast cancer patients.
    Tumori, 1992, Feb-29, Volume: 78, Issue:1

    Topics: Aminoimidazole Carboxamide; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carmustine; Drug Evaluation; Female; Fluorouracil; Humans; Prednisolone; Remission Induction; Retrospective Studies; Salvage Therapy; Time Factors

1992