aminoglutethimide has been researched along with Pregnancy in 74 studies
Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The hypothalamic-pituitary-adrenal axis is hyporesponsive to stress in late pregnancy, exemplified as reduced adrenocorticotropic hormone (ACTH) and corticosterone responses to restraint, but the mechanisms are unknown." | 3.70 | Attenuation of hypothalamic-pituitary-adrenal axis stress responses in late pregnancy: changes in feedforward and feedback mechanisms. ( Douglas, AJ; Johnstone, HA; Landgraf, R; Neumann, ID; Russell, JA; Seckl, JR; Wigger, A, 2000) |
| "Administration of aminoglutethimide (AG) at a daily sc dose of 20 mg/kg to rats from the 10th to 20th days of pregnancy resulted in fetal wastage, increased placental weights, and decreased placental alkaline phosphatase." | 3.67 | Effects of aminoglutethimide on cervical dilatability and serum immunoreactive relaxin in pregnant rats. ( Butler, MC; Munigle, J; O'Byrne, EM; Sawyer, WK; Steele, RE; Steinetz, BG, 1985) |
| " Blood pressure was normal during treatment with spironolactone and during pregnancy, when the action of aldosterone and other similar steroids was presumably blocked by an increased production of progesterone; this suggests that the hypertension is dependent upon sodium-retaining steroids such as aldosterone." | 3.66 | Overproduction of sodium-retaining steroids by the zona glomerulosa is adrenocorticotropin-dependent and mediates hypertension in dexamethasone-suppressible aldosteronism. ( Bartter, FC; Gill, JR, 1981) |
| "The inhibitory effect of d,l-aminoglutethimide (AG) on the synthesis of progesterone and estradiol in early human pregnancy (8th-12th week of gestation) was investigated in volunteers; control group (n = 11), AG group [1000 mg AG orally at test begin (n = 6)]." | 3.66 | Inhibition of human placental progesterone and estrogen synthesis in early human gestation by aminoglutethimide in vivo. ( Franke, C; Mösch, R; Nobakht, N; Rabe, T; Runnebaum, B, 1983) |
| "The ability of cultured midpregnancy mouse ovarian cells to synthesize progesterone de novo and from oxogenous pregnenolone has been assessed." | 3.65 | Gonadotrophin stimulation of progesterone synthesis by midpregnancy mouse ovarian cells in vitro. ( Salomon, DS; Sherman, MI, 1976) |
| " On days 7 to 9 of pregnancy, Wistar-strain pregnant rats were injected with either prostaglandin F2alpha (PGF2alpha), aminoglutethimide or clomiphene citrate (clomid)." | 3.65 | [Studies on the activities of steroidogenic enzymes in corpora lutea of early pregnant rats treated with abortifacient drugs (author's transl)]. ( Okazaki, T, 1975) |
| "These findings suggest that in molar pregnancy the decreased capacity of trophoblast tissue for the formation of estrogen could increase the testosterone concentration inside the molar vesicle, which, in turn, as we previously reported, inhibits progesterone formation." | 1.29 | Low aromatase activity in microsomes from complete hydatidiform mole. ( Alvarez, CI; Flury, A; Genti-Raimondi, S; Patrito, LC, 1993) |
| " If correct, two clinically available aromatase inhibitors, aminoglutethimide (AG) and testololactone (TL) could potentially be given together at lower than usual dosage with reduction of patient side effects and preservation of aromatase inhibition." | 1.27 | Additive effects of aminoglutethimide, testololactone, and 4-hydroxyandrostenedione as inhibitors of aromatase. ( Osawa, Y; Rosen, H; Santen, RJ; Santner, SJ, 1984) |
| " Progesterone decreased the secretion of hCG in a dose-response manner (r = -0." | 1.26 | Suppression of human chorionic gonadotropin by progestational steroids. ( Dickson, LR; Jawad, MJ; Wilson, EA, 1980) |
| "Aminoglutethimide (AG) is an inhibitor of P-450 linked steroid hydroxylation reactions including the cholesterol side chain cleavage, which is the rate-limiting step by which the synthesis of pregnenolone and also progesterone can be controlled." | 1.26 | Inhibition of human placental progesterone synthesis by aminoglutethimide in vitro. ( Rabe, D; Rabe, T; Runnebaum, B; Weidenhammer, K, 1982) |
| "In aminoglutethimide-treated rats, the activities of G6PDH and malic enzyme decreased, while 20alpha-HSD activity was maintained at a very low level." | 1.26 | An enzymologic study of corpora lutea in early pregnant rats treated with abortifacient agents. ( Morikawa, H; Motohashi, T; Okamura, H; Okazaki, T; Yogo, I, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 55 (74.32) | 18.7374 |
| 1990's | 13 (17.57) | 18.2507 |
| 2000's | 6 (8.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bayer, H | 1 |
| Batzl, C | 2 |
| Hartmann, RW | 2 |
| Mannschreck, A | 1 |
| Rowlands, MG | 2 |
| Bunnett, MA | 1 |
| Foster, AB | 2 |
| Jarman, M | 2 |
| Stanek, J | 1 |
| Schweizer, E | 1 |
| Leung, CS | 1 |
| Taylor, GN | 1 |
| Vinh, TK | 1 |
| Ahmadi, M | 1 |
| Delgado, PO | 1 |
| Perez, SF | 1 |
| Walters, HM | 1 |
| Smith, HJ | 1 |
| Nicholls, PJ | 1 |
| Simons, C | 1 |
| Lee, D | 1 |
| Bhat, KP | 1 |
| Fong, HH | 1 |
| Farnsworth, NR | 1 |
| Pezzuto, JM | 1 |
| Kinghorn, AD | 1 |
| Pouget, C | 1 |
| Fagnere, C | 1 |
| Basly, JP | 1 |
| Habrioux, G | 1 |
| Chulia, AJ | 1 |
| Neves, MA | 1 |
| Dinis, TC | 1 |
| Colombo, G | 1 |
| Sá e Melo, ML | 1 |
| Wilson, EA | 1 |
| Jawad, MJ | 1 |
| Dickson, LR | 1 |
| Gill, JR | 1 |
| Bartter, FC | 1 |
| Evans, CA | 1 |
| Kennedy, TG | 1 |
| Kellis, JT | 1 |
| Vickery, LE | 2 |
| Matt, DW | 1 |
| MacDonald, GJ | 1 |
| Santner, SJ | 1 |
| Rosen, H | 1 |
| Osawa, Y | 1 |
| Santen, RJ | 1 |
| Rabe, T | 3 |
| Mösch, R | 1 |
| Franke, C | 1 |
| Nobakht, N | 1 |
| Runnebaum, B | 3 |
| Graves, PE | 2 |
| Uzgiris, VI | 1 |
| Salhanick, HA | 3 |
| Inaba, T | 1 |
| Wiest, WG | 1 |
| Rabe, D | 2 |
| Weidenhammer, K | 1 |
| Lemon, M | 1 |
| Mauléon, P | 1 |
| Brodie, AM | 2 |
| Sheets, JJ | 1 |
| Simpson, ER | 2 |
| Burkhart, MF | 1 |
| Abul-Hajj, YJ | 1 |
| Sawada, M | 1 |
| Kitamura, R | 1 |
| Norose, T | 1 |
| Kitada, M | 1 |
| Itahashi, K | 1 |
| Kamataki, T | 1 |
| Genti-Raimondi, S | 1 |
| Alvarez, CI | 1 |
| Patrito, LC | 1 |
| Flury, A | 1 |
| Duan, WR | 1 |
| Parmer, TG | 1 |
| Albarracin, CT | 1 |
| Zhong, L | 1 |
| Gibori, G | 2 |
| Omigbodun, A | 1 |
| Ziolkiewicz, P | 1 |
| Tessler, C | 1 |
| Hoyer, JR | 1 |
| Coutifaris, C | 1 |
| Shanker, YG | 1 |
| Shetty, UP | 1 |
| Rao, AJ | 1 |
| Yamada, K | 1 |
| Sugawara, S | 1 |
| Ohmori, K | 1 |
| Ohta, A | 1 |
| Johnstone, HA | 1 |
| Wigger, A | 1 |
| Douglas, AJ | 1 |
| Neumann, ID | 1 |
| Landgraf, R | 1 |
| Seckl, JR | 1 |
| Russell, JA | 1 |
| Cheng, KW | 1 |
| Cheng, CK | 1 |
| Leung, PC | 1 |
| Kawai, M | 1 |
| Swan, KF | 1 |
| Green, AE | 1 |
| Edwards, DE | 1 |
| Anderson, MB | 1 |
| Henson, MC | 1 |
| McLaren, EH | 1 |
| Alexander, WD | 1 |
| George, FW | 1 |
| Milewich, L | 1 |
| Wilson, JD | 1 |
| Rodway, RG | 1 |
| Kuhn, NJ | 2 |
| Steinetz, BG | 3 |
| Niemann, WH | 1 |
| Giannina, T | 2 |
| Duncan, D | 1 |
| Chart, JJ | 1 |
| Brinkmann, AO | 1 |
| Salomon, DS | 1 |
| Sherman, MI | 1 |
| Okazaki, T | 3 |
| Okamura, H | 2 |
| Motohashi, T | 2 |
| Morikawa, H | 2 |
| Yogo, I | 1 |
| Butler, MC | 2 |
| Sawyer, WK | 2 |
| O'Byrne, EM | 2 |
| Smith, DH | 1 |
| Yoshida, Y | 1 |
| Sheridan, PJ | 1 |
| Phillips, JL | 1 |
| Simmons, KR | 1 |
| Caffrey, JL | 1 |
| Abel, JH | 1 |
| Niswender, GD | 1 |
| Torres, CA | 1 |
| First, NL | 1 |
| Tsutsui, K | 1 |
| Newton, CJ | 1 |
| Mehta, A | 1 |
| Dowsett, M | 1 |
| Zhou, DJ | 2 |
| Korzekwa, KR | 1 |
| Poulos, T | 1 |
| Chen, SA | 2 |
| Pompon, D | 1 |
| Puryear, TK | 1 |
| McLean, MP | 1 |
| Khan, I | 1 |
| Ullmann, MB | 1 |
| Reimers, TJ | 1 |
| Sasaki, J | 1 |
| Yamamoto, T | 2 |
| Okada, H | 2 |
| Rose, JC | 1 |
| Turner, CS | 1 |
| Ray, D | 1 |
| Rawashdeh, N | 1 |
| Volkenandt, M | 1 |
| Büchner, T | 1 |
| Hiddemann, W | 1 |
| Van de Loo, J | 1 |
| Pasanen, M | 1 |
| Taskinen, T | 1 |
| Sotaniemi, EA | 1 |
| Kairaluoma, M | 1 |
| Pelkonen, O | 1 |
| Urabe, M | 1 |
| Wing, LY | 1 |
| Garrett, WM | 1 |
| Munigle, J | 1 |
| Steele, RE | 1 |
| Leung, P | 1 |
| Gidari, AS | 1 |
| Marek, J | 1 |
| Horký, K | 1 |
| Purvis, JL | 1 |
| Canick, JA | 1 |
| Rosenbaum, JH | 1 |
| Hologgitas, J | 1 |
| Latif, SA | 1 |
| Janne, O | 1 |
| Pastore, U | 1 |
| Timonen, H | 1 |
| Vihko, R | 1 |
| Thompson, EA | 1 |
| Siiteri, PK | 1 |
| Eversole, WJ | 1 |
| Thompson, DJ | 1 |
| Hanson, TJ | 1 |
| Ballonoff, LB | 1 |
| Northcutt, RC | 2 |
| Drost, M | 1 |
| Kumagai, LF | 1 |
| Guzman, M | 1 |
| Jost, A | 1 |
| Glasser, SR | 1 |
| Chytil, F | 1 |
| Strott, CA | 1 |
| LeMaire, WJ | 1 |
| Cleveland, WW | 1 |
| Bejar, RL | 1 |
| Marsh, JM | 1 |
| Fishman, L | 1 |
| Goldman, AS | 2 |
2 reviews available for aminoglutethimide and Pregnancy
| Article | Year |
|---|---|
Goitrogens.
Topics: Adult; Aminoglutethimide; Animals; Antithyroid Agents; Carbimazole; Cobalt; Ethionamide; Female; Fet | 1979 |
Use of androgen antagonists and antiandrogens in studies on sex differentiation.
Topics: Abnormalities, Drug-Induced; Aminoglutethimide; Androgen Antagonists; Androstenes; Animals; Cattle; | 1971 |
72 other studies available for aminoglutethimide and Pregnancy
| Article | Year |
|---|---|
New aromatase inhibitors. Synthesis and biological activity of pyridyl-substituted tetralone derivatives.
Topics: Animals; Aromatase Inhibitors; Chromatography, High Pressure Liquid; Female; Humans; Lyases; Magneti | 1991 |
Analogues of aminoglutethimide based on 1-phenyl-3-azabicyclo[3.1.0]hexane-2,4-dione: selective inhibition of aromatase activity.
Topics: Aminoglutethimide; Aromatase; Aromatase Inhibitors; Bridged Bicyclo Compounds; Bridged Bicyclo Compo | 1988 |
Aromatase inhibitors. Synthesis and evaluation of mammary tumor inhibiting activity of 3-alkylated 3-(4-aminophenyl)piperidine-2,6-diones.
Topics: Adrenal Glands; Alkylation; Animals; Aromatase Inhibitors; Cattle; Crystallization; Estrogens; Femal | 1986 |
Analogues of aminoglutethimide: selective inhibition of cholesterol side-chain cleavage.
Topics: Aminoglutethimide; Animals; Aromatase Inhibitors; Cattle; Chemical Phenomena; Chemistry; Cholesterol | 1983 |
1-[(Benzofuran-2-yl)phenylmethyl]-triazoles and -tetrazoles - potent competitive inhibitors of aromatase.
Topics: Aminoglutethimide; Androstenedione; Aromatase; Aromatase Inhibitors; Benzofurans; Enzyme Inhibitors; | 1999 |
Aromatase inhibitors from Broussonetia papyrifera.
Topics: Algorithms; Anticarcinogenic Agents; Aromatase; Aromatase Inhibitors; Benzofurans; Chalcone; Chalcon | 2001 |
Design, synthesis and evaluation of 4-imidazolylflavans as new leads for aromatase inhibition.
Topics: Aromatase; Aromatase Inhibitors; Drug Design; Enzyme Inhibitors; Female; Flavonoids; Humans; Imidazo | 2002 |
An efficient steroid pharmacophore-based strategy to identify new aromatase inhibitors.
Topics: Androstenedione; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; | 2009 |
Suppression of human chorionic gonadotropin by progestational steroids.
Topics: Aminoglutethimide; Androgens; Androstanols; Bucladesine; Chorionic Gonadotropin; Dihydrotestosterone | 1980 |
Overproduction of sodium-retaining steroids by the zona glomerulosa is adrenocorticotropin-dependent and mediates hypertension in dexamethasone-suppressible aldosteronism.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Aldosterone; Aminoglutethimide; Child, Preschool | 1981 |
Blastocyst implantation in ovariectomized, adrenalectomized hamsters treated with inhibitors of steroidogenesis during the pre-implantation period.
Topics: Adrenalectomy; Aminoglutethimide; Animals; Blastocyst; Castration; Cricetinae; Cyanoketone; Embryo I | 1980 |
Inhibition of estrogen synthetase (aromatase) by 4-cyclohexylaniline.
Topics: Aminoglutethimide; Aniline Compounds; Animals; Aromatase Inhibitors; Cell Fractionation; Estradiol; | 1984 |
In vitro progesterone and testosterone production by the rat placenta during pregnancy.
Topics: Aminoglutethimide; Animals; Cyanoketone; Dose-Response Relationship, Drug; Female; In Vitro Techniqu | 1984 |
Additive effects of aminoglutethimide, testololactone, and 4-hydroxyandrostenedione as inhibitors of aromatase.
Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Female; Humans; Kinetics; Microsomes; Oxid | 1984 |
Inhibition of human placental progesterone and estrogen synthesis in early human gestation by aminoglutethimide in vivo.
Topics: Aminoglutethimide; Estradiol; Estrogens; Female; Humans; Kinetics; Placenta; Pregnancy; Pregnancy Tr | 1983 |
Modification of enzymatic activity and difference spectra of cytochrome P-450 from various sources by cholesterol side chain cleavage inhibitors.
Topics: Adrenal Cortex; Aminoglutethimide; Aniline Compounds; Animals; Cattle; Cholesterol Side-Chain Cleava | 1980 |
Inhibitory effects of aminoglutethimide and isoxazole on progesterone production and deciduoma formation in rats.
Topics: 3-Hydroxysteroid Dehydrogenases; Aminoglutethimide; Animals; Decidua; Female; Isoxazoles; Kinetics; | 1980 |
Inhibition of human placental progesterone synthesis by aminoglutethimide in vitro.
Topics: 20-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Aminoglutethimide; Female; Humans | 1982 |
Interaction between two luteal cell types from the corpus luteum of the sow in progesterone synthesis in vitro.
Topics: Abortifacient Agents, Steroidal; Aminoglutethimide; Animals; Cells, Cultured; Cholesterol; Corpus Lu | 1982 |
Overview of recent development of aromatase inhibitors.
Topics: Aminoglutethimide; Androstatrienes; Androstenedione; Animals; Aromatase Inhibitors; Breast Neoplasms | 1982 |
Basic studies on aminoglutethimide.
Topics: Adrenalectomy; Aminoglutethimide; Aromatase Inhibitors; Breast Neoplasms; Castration; Cholesterol; C | 1982 |
New aromatase assay and its application for inhibitory studies of aminoglutethimide on microsomes of human term placenta.
Topics: Aminoglutethimide; Androstenedione; Aromatase; Female; Humans; Kinetics; Microsomes; Oxidoreductases | 1982 |
Effects of aminoglutethiumide and its metabolite, N-acetylaminoglutethimide, on bovine adrenocortical and human placental cytochromes P-450scc.
Topics: Adrenal Cortex; Aminoglutethimide; Animals; Cattle; Cholesterol; Cytochrome P-450 Enzyme Inhibitors; | 1982 |
Regulation of cholesterol metabolism by human choriocarcinoma cells in culture: effect of lipoproteins and progesterone on cholesteryl ester synthesis.
Topics: Aminoglutethimide; Cells, Cultured; Chloroquine; Cholesterol; Cholesterol Esters; Choriocarcinoma; F | 1980 |
Inhibition of androgen aromatization in human breast cancer.
Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Breast Neoplasms; Carbon Radioisotopes; Es | 1980 |
Metabolic activation of aflatoxin B1 by human placental microsomes.
Topics: Aflatoxin B1; Aminoglutethimide; Benzoflavones; beta-Naphthoflavone; Biotransformation; Cytochrome P | 1993 |
Low aromatase activity in microsomes from complete hydatidiform mole.
Topics: Abortion, Therapeutic; Aminoglutethimide; Aromatase; Female; Humans; Hydatidiform Mole; Kinetics; Mi | 1993 |
PRAP, a prolactin receptor associated protein: its gene expression and regulation in the corpus luteum.
Topics: Aminoglutethimide; Animals; Aromatase Inhibitors; Blotting, Northern; Blotting, Western; Calcium-Bin | 1997 |
Progesterone regulates osteopontin expression in human trophoblasts: a model of paracrine control in the placenta?
Topics: Aminoglutethimide; Blotting, Northern; Cell Communication; Cell Differentiation; Cells, Cultured; Ch | 1997 |
Regulation of low density lipoprotein receptor mRNA levels by estradiol 17beta and chorionic gonadotropin in human placenta.
Topics: Aminoglutethimide; Androstatrienes; Aromatase Inhibitors; Blotting, Northern; Cholesterol; Chorionic | 1998 |
Effect of 3,6-dimethylpyrazine-2-thiol on androstenedione-induced increase of uterine weight in female rats.
Topics: Aminoglutethimide; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Drug Interactions; Enz | 1999 |
Attenuation of hypothalamic-pituitary-adrenal axis stress responses in late pregnancy: changes in feedforward and feedback mechanisms.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutet | 2000 |
Differential role of PR-A and -B isoforms in transcription regulation of human GnRH receptor gene.
Topics: Aminoglutethimide; Animals; Blotting, Western; Dexamethasone; Enzyme Inhibitors; Female; Gene Expres | 2001 |
Placental endocrine disruption induced by cadmium: effects on P450 cholesterol side-chain cleavage and 3beta-hydroxysteroid dehydrogenase enzymes in cultured human trophoblasts.
Topics: 3-Hydroxysteroid Dehydrogenases; 8-Bromo Cyclic Adenosine Monophosphate; Aminoglutethimide; Cadmium; | 2002 |
Stereoselective inhibition of aromatase by enantiomers of aminoglutethimide.
Topics: Aminoglutethimide; Aromatase Inhibitors; Cytochrome P-450 Enzyme System; Female; Humans; Kinetics; M | 1979 |
Studies on the regulation of the onset of steroid hormone biosynthesis in fetal rabbit gonads.
Topics: Aminoglutethimide; Androgens; Animals; Estradiol; Female; Fetus; Gestational Age; Male; Ovary; Pregn | 1979 |
Hormonal control of Luteal 20alpha-Hydroxy steroid dehydrogenase and delta5-3beta-hydroxy steroid dehydrogenase during luteolysis in the pregnant rat.
Topics: Aminoglutethimide; Animals; Chorionic Gonadotropin; Corpus Luteum; Estrogens; Female; Fetus; Gonadot | 1975 |
Effect of aminoglutethimide on serum progesterone and estrogen in the pregnant baboon (Papio SP).
Topics: Abortion, Spontaneous; Aminoglutethimide; Animals; Estrogens; Female; Haplorhini; Papio; Pregnancy; | 1975 |
Testosterone synthesis in vitro by the fetal testis of the guinea pig.
Topics: Aminoglutethimide; Animals; Female; Gestational Age; Guinea Pigs; Male; Organ Culture Techniques; Pr | 1977 |
Gonadotrophin stimulation of progesterone synthesis by midpregnancy mouse ovarian cells in vitro.
Topics: Aminoglutethimide; Animals; Cells, Cultured; Chorionic Gonadotropin; Female; Kinetics; Male; Mice; M | 1976 |
An enzymologic study of corpora lutea in early pregnant rats treated with abortifacient agents.
Topics: Abortifacient Agents; Aminoglutethimide; Animals; ATP Citrate (pro-S)-Lyase; Clomiphene; Corpus Lute | 1976 |
Post-implantation termination of pregnancy in rats.
Topics: Abortifacient Agents; Alkaline Phosphatase; Aminoglutethimide; Animals; Cyclofenil; Diethylstilbestr | 1976 |
A proposed sequence of hormones controlling the induction of luteal 20alpha-hydroxy steroid dehydrogenase and progesterone withdrawal in the late-pregnant rat.
Topics: Aminoglutethimide; Animals; Corpus Luteum; Enzyme Induction; Female; Gonadotropins; Hydroxysteroid D | 1976 |
Effect of aminoglutethimide on corpora lutea of pregnant rats.
Topics: Aminoglutethimide; Animals; Corpus Luteum; Female; Histocytochemistry; Microscopy, Electron; Pregnan | 1976 |
Modulation of the uptake and retention of estradiol-17beta in the ovine corpus luteum by luteinizing hormone.
Topics: Aminoglutethimide; Animals; Cell Survival; Corpus Luteum; Estradiol; Estriol; Estrone; Estrus; Femal | 1975 |
[Studies on the activities of steroidogenic enzymes in corpora lutea of early pregnant rats treated with abortifacient drugs (author's transl)].
Topics: Abortifacient Agents; Alcohol Oxidoreductases; Aminoglutethimide; Animals; Clomiphene; Corpus Luteum | 1975 |
Gestation length in rabbits-effect of aminoglutethimide phosphate, dexamethasone, pregnenolone and progesterone.
Topics: Adrenal Glands; Aminoglutethimide; Animals; Animals, Newborn; Corpus Luteum; Dexamethasone; Female; | 1976 |
Inhibitory role of sex steroid in the regulation of ovarian follicle-stimulating hormone receptors during pregnancy.
Topics: Aminoglutethimide; Animals; Female; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Male; Ov | 1992 |
The effect of the aromatase inhibitor, rogletimide (pyridoglutethimide), on guinea pig adrenal cell steroidogenesis and placental microsomal aromatase activity: comparison with aminoglutethimide and CGS 16949A.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Aromatase; Aromatase Inhibi | 1991 |
A site-directed mutagenesis study of human placental aromatase.
Topics: Aminoglutethimide; Animals; Aromatase; Aromatase Inhibitors; Base Sequence; Binding Sites; Chromatog | 1992 |
Stable expression of human aromatase complementary DNA in mammalian cells: a useful system for aromatase inhibitor screening.
Topics: Aminoglutethimide; Androstenedione; Animals; Aromatase; Aromatase Inhibitors; Base Sequence; Blottin | 1990 |
Mechanism for control of hydroxymethylglutaryl-coenzyme A reductase and cytochrome P-450 side chain cleavage message and enzyme in the corpus luteum.
Topics: Adenine; Aminoglutethimide; Animals; Anticholesteremic Agents; Cholesterol; Cholesterol Esters; Chol | 1990 |
Progesterone production by binucleate trophoblastic cells of cows.
Topics: Aminoglutethimide; Animals; Calcimycin; Calcium; Calmodulin; Cattle; Cells, Cultured; Cholesterol, H | 1989 |
[The synergistic abortive effect of anti-progestogen RU 38486 and aromatase inhibitors for pregnant rat].
Topics: Abortifacient Agents; Abortifacient Agents, Steroidal; Aminoglutethimide; Animals; Aromatase; Estren | 1989 |
Evidence that cortisol inhibits basal adrenocorticotropin secretion in the sheep fetus by 0.70 gestation.
Topics: Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Carbon Dioxide; Female; Fetal Blood; Fetus; | 1988 |
Acute leukaemia during pregnancy.
Topics: Adult; Aminoglutethimide; Antineoplastic Combined Chemotherapy Protocols; Danazol; Female; Humans; I | 1987 |
Inhibitor panel studies of human hepatic and placental cytochrome P-450-associated monooxygenase activities.
Topics: Aminoglutethimide; Animals; Benzoflavones; Cimetidine; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enz | 1988 |
[The inhibitory effect of miconazole on aromatase activity for androstenedione in human placental and ovarian preparations].
Topics: Aminoglutethimide; Androstenedione; Aromatase Inhibitors; Female; Humans; In Vitro Techniques; Micon | 1987 |
Effects of aromatase inhibitors, aminoglutethimide, and 4-hydroxyandrostenedione on cyclic rats and rats with 7,12-dimethylbenz(a)anthracene-induced mammary tumors.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoglutethimide; Androstenedione; Animals; Aromatase Inhibitors; | 1985 |
Effects of aminoglutethimide on cervical dilatability and serum immunoreactive relaxin in pregnant rats.
Topics: Aminoglutethimide; Animals; Cervix Uteri; Estradiol; Female; Pregnancy; Pregnancy, Animal; Progester | 1985 |
Effect of aminoglutethimide on murine fetal hepatic erythroid colony formation.
Topics: Aminoglutethimide; Animals; Erythrocytes; Erythropoietin; Female; Hematopoietic Stem Cells; Liver; M | 1985 |
Aminoglutethimide administration in pregnancy.
Topics: Adrenal Glands; Adult; Aldosterone; Aminoglutethimide; Aniline Compounds; Animals; Anticonvulsants; | 1970 |
Control of cytochrome P-450 in rat testis mitochondria by human chorionic gonadotrophin.
Topics: Aminoglutethimide; Animals; Chorionic Gonadotropin; Cytochrome c Group; Cytochrome P-450 Enzyme Syst | 1973 |
Plasma and urinary steroids in pregnant women during p-aminoglutethimide treatment.
Topics: 17-Ketosteroids; Abortion, Induced; Adrenal Cortex Hormones; Aminoglutethimide; Androstenols; Andros | 1974 |
The involvement of human placental microsomal cytochrome P-450 in aromatization.
Topics: Aminoglutethimide; Androstenedione; Animals; Binding Sites; Binding, Competitive; Carbon Monoxide; C | 1974 |
Effect of aminoglutethimide on reproductive processes in female rats.
Topics: Aminoglutethimide; Animals; Animals, Newborn; Ataxia; Estrus; Female; Fertility; Injections, Subcuta | 1974 |
Letter: Amino-glutethimide and pregnancy.
Topics: Adult; Aminoglutethimide; Cushing Syndrome; Female; Fetus; Gestational Age; Humans; Infant, Newborn; | 1974 |
Sequential foetal-maternal plasma cortisol levels in sheep.
Topics: Adrenal Glands; Aminoglutethimide; Animals; Female; Fetus; Fluorometry; Gestational Age; Hydrocortis | 1973 |
The influence of an anti-steroidogenic drug (aminoglutethimide phosphate) on pregnancy maintenance.
Topics: Abortion, Induced; Aminoglutethimide; Aniline Compounds; Animals; Anticonvulsants; Biotransformation | 1972 |
Aminoglutethimide: a possible cause of pseudohermaphroiditism in females.
Topics: Adult; Aminoglutethimide; Aniline Compounds; Animals; Anticonvulsants; Child, Preschool; Disorders o | 1972 |
Production of congenital lipoid adrenal hyperplasia in rats and inhibition of cholesterol side-chain cleavage.
Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Aminoglutethimide; Aniline Compounds; Animals; Anti | 1970 |
Experimental congenital lipoid adrenal hyperplasia: prevention of anatomic defects produced by aminoglutethimide.
Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Aminoglutethimide; Aniline Compounds; Animals; Anti | 1970 |