aminoglutethimide has been researched along with Melanoma in 3 studies
Aminoglutethimide: An aromatase inhibitor that is used in the treatment of advanced BREAST CANCER.
aminoglutethimide : A dicarboximide that is a six-membered cyclic compound having ethyl and 4-aminophenyl substituents at the 3-position.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The role of steroid hormones has been suggested in the growth of malignant melanoma, and since aromatase activity has been found in melanoma tissue, we carried out a phase II study of aminoglutethimide, an aromatase inhibitor in malignant melanoma patients." | 9.07 | Aminoglutethimide in malignant melanoma. A phase II study. ( Adenis, A; Block, S; Bonneterre, J; Demaille, A; Pion, JM, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Block, S | 1 |
| Bonneterre, J | 1 |
| Adenis, A | 1 |
| Pion, JM | 1 |
| Demaille, A | 1 |
| Santen, RJ | 1 |
| Santner, SJ | 1 |
| Harvey, HA | 1 |
| Lipton, A | 1 |
| Simmonds, M | 1 |
| Feil, PD | 1 |
| Manders, E | 1 |
| Davis, TS | 1 |
| Carey, RM | 1 |
| Orth, DN | 1 |
| Hartmann, WH | 1 |
1 trial available for aminoglutethimide and Melanoma
| Article | Year |
|---|---|
Aminoglutethimide in malignant melanoma. A phase II study.
Topics: Adult; Aged; Aminoglutethimide; Aromatase Inhibitors; Drug Evaluation; Humans; Melanoma; Middle Aged | 1992 |
2 other studies available for aminoglutethimide and Melanoma
| Article | Year |
|---|---|
Marked heterogeneity of aromatase activity in human malignant melanoma tissue.
Topics: Adult; Aged; Aminoglutethimide; Aromatase; Aromatase Inhibitors; Biomarkers, Tumor; Estradiol; Estro | 1988 |
Malignant melanoma with ectopic production of adrenocorticotropic hormone. Palliative treatment with inhibitors of adrenal steroid biosynthesis.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocortical Hyperfunction; Adrenocorticotropic Hormon | 1973 |